subject:(Small cells)

Queens University

1. Qutqut, Mahmoud. Mobile Small cells in Cellular Heterogeneous Networks .

Degree: Computing, 2014, Queens University

URL: http://hdl.handle.net/1974/12538

► The unprecedented soaring demand for capacity and coverage on cellular networks is challenging and straining operators. The current improvements in cellular standards are significantly behind… (more)

▼ The unprecedented soaring demand for capacity and coverage on cellular networks is challenging and straining operators. The current improvements in cellular standards are significantly behind the exponential growth in requirements. Cellular operators are currently shifting towards Heterogeneous Networks (HetNets) as the most promis- ing solution to meet user demands; by using a mix of Macro Base Stations (MBSs) and Small Base Stations (SBSs). Recently, several cellular operators have started outdoor deployments of small cells to enhance service in high-dense areas (e.g., downtown areas). In this the- sis we assess and propose HetNet solutions that capitalize on SBS deployments to boost capacity and coverage under varying scenarios. Initially we investigate the core challenge of SBS placement in high-demand outdoor zones. We propose dynamic placement strategies (DPS) for SBSs, and present two models that optimize placement while minimizing service delivery cost when feasibility is the core challenge, and minimizing macrocells utilization as their deployment, compared to small cells, pose a constant challenges. Both problems are formulated as Mixed Integer Linear Pro- grams (MILPs). These solutions are contrasted to two greedy schemes which we have presented and evaluated over extensive simulations. Our simulation results demonstrate that our proposed DPS achieve significant reductions of service delivery cost and MBSs utilization. Realizing that a significant cant amount of cellular demand is generated on the go and suffers deteriorating quality, recent research efforts proposed deploying SBSs onboard public transit vehicles to enhance cellular coverage. We investigate the potential performance gains of using mobile SBSs (mobSBSs). We assess and quantify the impact of utilizing mobSBSs which are deployed in vehicles to aggregate traffic and backhaul it to MBS. In our evaluation we study two important indicators to assess the Quality of Service (QoS) received by mobile users, and the ensuing network performance. Namely, we investigate Pairwise Error Probability (PEP) and Outage Probability (OP) for mobile users. Finally, we propose a novel mobile data offloading framework which capitalizes on mobile small cells and urban Wireless Fidelity (WiFi) zones to alleviate the data tra c load generated onboard on MBSs. We incorporate dedicated and adaptive offloading mechanisms that take into account mobile user service profiles (history) and WiFi coverage maps to improve the e efficiency of the offloading framework. We conduct extensive simulation experiments to evaluate the performance of the mobile offloading framework and contrast results to a benchmark.

Subjects/Keywords: Heterogeneous Networks ; Small Cells

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APA (6^th Edition):

Qutqut, M. (2014). Mobile Small cells in Cellular Heterogeneous Networks . (Thesis). Queens University. Retrieved from http://hdl.handle.net/1974/12538

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Qutqut, Mahmoud. “Mobile Small cells in Cellular Heterogeneous Networks .” 2014. Thesis, Queens University. Accessed April 11, 2021. http://hdl.handle.net/1974/12538.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Qutqut, Mahmoud. “Mobile Small cells in Cellular Heterogeneous Networks .” 2014. Web. 11 Apr 2021.

Vancouver:

Qutqut M. Mobile Small cells in Cellular Heterogeneous Networks . [Internet] [Thesis]. Queens University; 2014. [cited 2021 Apr 11]. Available from: http://hdl.handle.net/1974/12538.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Qutqut M. Mobile Small cells in Cellular Heterogeneous Networks . [Thesis]. Queens University; 2014. Available from: http://hdl.handle.net/1974/12538

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Virginia Tech

2. Reynolds, Krista Lynn. Effects of high incubation temperature on the developing small intestine and yolk sac of broiler chicks with insight into goblet cell development in the small intestine early posthatch.

Degree: MS, Animal and Poultry Sciences, 2019, Virginia Tech

URL: http://hdl.handle.net/10919/102122

► The incubation period is crucial for development and overall quality of a chick. The selection for fast growing broilers has allowed the birds to reach… (more)

▼ The incubation period is crucial for development and overall quality of a chick. The selection for fast growing broilers has allowed the birds to reach market weight at a faster rate making the incubation period a larger portion of a broiler's life. A faster growth rate can lead to the release of more metabolic heat inside of the egg toward the second half of incubation because the embryo shifts to a homeothermic state. More heat being released into the incubator can cause the incubation temperature to rise if the incubator is not electronically regulated or cannot be ventilated properly due to malfunction. A high incubation temperature can impact the hatchability, growth, and development of the chick. This thesis provides a more in-depth analysis of the effects of high incubation temperature (37.5°C versus 39.5°C) on the developing small intestine and yolk sac, which provide the chick with nutrients posthatch and during embryogenesis. Studying these organs and mechanisms occurring during this time could potentially indicate why chicks from eggs subjected to a higher incubation temperature are not developing and growing properly. Chicks from eggs incubated at a higher temperature had lower body weights, lower hatchability and lower villus height in the duodenum, jejunum, and ileum. There were also differences seen in the depth of the crypt, which is the site for stem cells. Chicks from eggs incubated at a higher temperature had a lower crypt depth in the duodenum and jejunum. There was no difference in the expression of the intestinal stem cell marker olfactomedin 4 (Olfm4) and mucin 2, which is secreted by goblet cells and forms mucus. In the yolk sac, heat shock proteins (HSP) 70 and 90 were elevated at embryonic day 15, and HSP90 still remained elevated at embryonic day 17. Chicks from eggs incubated at a higher temperature showed greater expression of peptide transporter 1 and avian beta-defensin 10 mRNA at embryonic day 13. Even though small intestinal morphology was impacted early posthatch and expression of genes in the yolk sac were elevated at embryonic day 13, there does not seem to be a long-lasting effect on the development of the small intestine or the yolk sac. It is still important to study the impact of the incubation environment to understand the development and growth of the chicks and how different incubation factors can impact the overall hatchability and health of the chick. Advisors/Committee Members: Wong, Eric A. (committeechair), Dalloul, Rami A. (committee member), Gilbert, Elizabeth Ruth (committee member).

Subjects/Keywords: Incubation temperature; Broiler; Small Intestine; Yolk sac; Stem cells; Goblet cells; In situ hybridization; qPCR

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APA (6^th Edition):

Reynolds, K. L. (2019). Effects of high incubation temperature on the developing small intestine and yolk sac of broiler chicks with insight into goblet cell development in the small intestine early posthatch. (Masters Thesis). Virginia Tech. Retrieved from http://hdl.handle.net/10919/102122

Chicago Manual of Style (16^th Edition):

Reynolds, Krista Lynn. “Effects of high incubation temperature on the developing small intestine and yolk sac of broiler chicks with insight into goblet cell development in the small intestine early posthatch.” 2019. Masters Thesis, Virginia Tech. Accessed April 11, 2021. http://hdl.handle.net/10919/102122.

MLA Handbook (7^th Edition):

Reynolds, Krista Lynn. “Effects of high incubation temperature on the developing small intestine and yolk sac of broiler chicks with insight into goblet cell development in the small intestine early posthatch.” 2019. Web. 11 Apr 2021.

Vancouver:

Reynolds KL. Effects of high incubation temperature on the developing small intestine and yolk sac of broiler chicks with insight into goblet cell development in the small intestine early posthatch. [Internet] [Masters thesis]. Virginia Tech; 2019. [cited 2021 Apr 11]. Available from: http://hdl.handle.net/10919/102122.

Council of Science Editors:

Reynolds KL. Effects of high incubation temperature on the developing small intestine and yolk sac of broiler chicks with insight into goblet cell development in the small intestine early posthatch. [Masters Thesis]. Virginia Tech; 2019. Available from: http://hdl.handle.net/10919/102122

3. 山岡, 真美. PI3K regulates endocytosis after insulin secretion by mediating signaling crosstalk between Arf6 and Rab27a.

Degree: 博士(医学), 2017, Oita University / 大分大学

URL: http://hdl.handle.net/10559/15698

► In secretory cells, endocytosis is coupled to exocytosis to enable proper secretion. Although endocytosis is crucial to maintain cellular homeostasis before and after secretion, knowledge… (more)

Subjects/Keywords: Endocytosis; Small GTPase; Insulin; Membrane trafficking; Diabetes; Pancreatic β-cells

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APA (6^th Edition):

山岡, �. (2017). PI3K regulates endocytosis after insulin secretion by mediating signaling crosstalk between Arf6 and Rab27a. (Thesis). Oita University / 大分大学. Retrieved from http://hdl.handle.net/10559/15698

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

山岡, 真美. “PI3K regulates endocytosis after insulin secretion by mediating signaling crosstalk between Arf6 and Rab27a.” 2017. Thesis, Oita University / 大分大学. Accessed April 11, 2021. http://hdl.handle.net/10559/15698.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

山岡, 真美. “PI3K regulates endocytosis after insulin secretion by mediating signaling crosstalk between Arf6 and Rab27a.” 2017. Web. 11 Apr 2021.

Vancouver:

山岡 �. PI3K regulates endocytosis after insulin secretion by mediating signaling crosstalk between Arf6 and Rab27a. [Internet] [Thesis]. Oita University / 大分大学; 2017. [cited 2021 Apr 11]. Available from: http://hdl.handle.net/10559/15698.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

山岡 �. PI3K regulates endocytosis after insulin secretion by mediating signaling crosstalk between Arf6 and Rab27a. [Thesis]. Oita University / 大分大学; 2017. Available from: http://hdl.handle.net/10559/15698

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Utah

4. Pallavicini, Maria Georgina. In vivo effects of ftorafur and fluorouracil on mammary tumors and small intestine in mice.

Degree: PhD, Pharmacology & Toxicology;, 1997, University of Utah

URL: http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/1082/rec/629

► The in vivo effects of Ftorafur (FT) and 5-fluorouracil (FU) were evaluated at several different organizational levels within the same animal model. On a molar… (more)

▼ The in vivo effects of Ftorafur (FT) and 5-fluorouracil (FU) were evaluated at several different organizational levels within the same animal model. On a molar basis, FU was found to be two to three times more potent than FT with respect to growth inhibition of murine mammary adenocarcinomas. However, administration of FT produced less host toxicity at a dose level which resulted in similar antitumor activity. Drug-induced perturbations in cell cycle phase distributions were analyzed by the flow cytometer (FCM). Although FCM analysis is limited by lack of information on the extent of dead and dying cells, data obtained with both drugs were consistent with the possibility of S phase cytotoxicity and drug-induce G1/S block or delay. Changes in the age distribution of perturbed tumor cells, is detected by FCM analysis, correlated with 3H-TdR autoradiography and with 32P incorporation into DNA but not with 3H-deoxyuridine incorporation into DNA. Both drugs depressed 3H-deosyuridine incorporation into DNA; however, incorporation in both the tumor and small intestine returned to control levels earlier with FT than with an equimolar dose of FU. However, both drugs produced similar patters of 3H-deoxyuridine incorporation when FT was administered at three times the molar equivalent dose of FU. The results of these studies also suggest that deoxyuridine incorporation primarily reflects drug effects on thymidylate synthetase and not necessarily the overall rate of DNA synthesis. This study also involved the development of techniques for the dispersal of solid tumors and intestinal lining epithelium into single cell suspensions for FCM analysis. Tetraphenylboron (TPB) was utilized as an aid to solid tumor dispersal. TPB-dispersed tumors yield DNA distributions with minimal cell clumping and low levels of cellular debris. Fluorescent enzyme histochemistry with subsequent FCM analysis was utilized to separate dispersed epithelial cells of the small intestine into crypt and villus subpopulations. When fully optimized, the epithelial cell separation should offer a rapid method by which perturbations in the age distribution of crypt cells can easily be evaluated by FCM.

Subjects/Keywords: Intestine, Small; Cells, Cultured

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APA (6^th Edition):

Pallavicini, M. G. (1997). In vivo effects of ftorafur and fluorouracil on mammary tumors and small intestine in mice. (Doctoral Dissertation). University of Utah. Retrieved from http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/1082/rec/629

Chicago Manual of Style (16^th Edition):

Pallavicini, Maria Georgina. “In vivo effects of ftorafur and fluorouracil on mammary tumors and small intestine in mice.” 1997. Doctoral Dissertation, University of Utah. Accessed April 11, 2021. http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/1082/rec/629.

MLA Handbook (7^th Edition):

Pallavicini, Maria Georgina. “In vivo effects of ftorafur and fluorouracil on mammary tumors and small intestine in mice.” 1997. Web. 11 Apr 2021.

Vancouver:

Pallavicini MG. In vivo effects of ftorafur and fluorouracil on mammary tumors and small intestine in mice. [Internet] [Doctoral dissertation]. University of Utah; 1997. [cited 2021 Apr 11]. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/1082/rec/629.

Council of Science Editors:

Pallavicini MG. In vivo effects of ftorafur and fluorouracil on mammary tumors and small intestine in mice. [Doctoral Dissertation]. University of Utah; 1997. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/1082/rec/629

NSYSU

5. Li, Wei-Luen. A Mathematical Model for Power Consumption in Small-Cell Embedded Macro Cell Networks.

Degree: Master, Communications Engineering, 2018, NSYSU

URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0030118-111600

► In this thesis, we propose a double cell embedded macro cell (DCEMC) networks architecture. We consider the coverage of small cells may overlap in a… (more)

Subjects/Keywords: Overlapping Small Cells; Power Consumption; Mobility; Mathematical Model; Macro Cell

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APA (6^th Edition):

Li, W. (2018). A Mathematical Model for Power Consumption in Small-Cell Embedded Macro Cell Networks. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0030118-111600

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Li, Wei-Luen. “A Mathematical Model for Power Consumption in Small-Cell Embedded Macro Cell Networks.” 2018. Thesis, NSYSU. Accessed April 11, 2021. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0030118-111600.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Li, Wei-Luen. “A Mathematical Model for Power Consumption in Small-Cell Embedded Macro Cell Networks.” 2018. Web. 11 Apr 2021.

Vancouver:

Li W. A Mathematical Model for Power Consumption in Small-Cell Embedded Macro Cell Networks. [Internet] [Thesis]. NSYSU; 2018. [cited 2021 Apr 11]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0030118-111600.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Li W. A Mathematical Model for Power Consumption in Small-Cell Embedded Macro Cell Networks. [Thesis]. NSYSU; 2018. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0030118-111600

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Edith Cowan University

6. Spencer, Isaac. Characterising PD-L1 expression in circulating melanoma and non-small cell lung cancer cells.

Degree: 2020, Edith Cowan University

URL: https://ro.ecu.edu.au/theses/2318

► Incidence rates for both melanoma and non-small cell lung cancer (NSCLC) have risen in recent decades. While advanced cases of both diseases have previously demonstrated… (more)

▼ Incidence rates for both melanoma and non-small cell lung cancer (NSCLC) have risen in recent decades. While advanced cases of both diseases have previously demonstrated low survivability, novel therapies such as immune checkpoint inhibitors, have significantly improved the outcome of patients suffering from these cancers. Recent clinical trials have led to the United States Food and Drug Administration (FDA) approving the use of antibodies targeting the PD-1 immune checkpoint for both melanoma and NSCLC. Anti-PD-1 antibodies have been seen to illicit responses in up to 40% of patients, however, particularly for melanoma, there is a lack of biomarkers to select for patients likely to respond. PD-L1 expression in tumour tissue is the most studied biomarker of response to anti-PD-1 therapy in melanoma patients and is also the biomarker currently in use as a companion diagnostic test for NSCLC patients. It is believed that circulating tumour cells (CTCs) that break away from the tumour and enter the bloodstream, would share the same immune escape mechanisms as the parent tumour, and so would express PD-L1 in the same way as the tumour. Therefore, we postulate that these cells provide an accessible tumour sample for analysis of PD-L1 expression. A previous study by our group used multi-marker flow cytometry to evaluated PD-L1 expression on CTCs from melanoma patients commencing anti-PD-L1 therapy. Here, the PDL1 expression on CTC from the latter study was compared to PD-L1 expression in matched tumour tissues. Moreover, this study describes the establishment of methodologies for immunocytochemistry analysis and scoring of PD-L1 expression on melanoma CTCs and on carcinomas CTCs, including NSCLC. Cell lines representing negative, low and high PD-L1 expression were identified to serve as controls, again for both melanoma and carcinomas. To further evaluate our methods, CTCs were extracted from the blood samples of patients with melanoma and NSCLC using microfluidic devices and immunostained to investigate the expression of PD-L1. Finally, comparison between CTC and tumour tissue PD-L1 expression was carried out in a small number of cases. Overall, this study successfully developed immunocytochemistry protocols to effectively identify and score PD-L1 expression on both melanoma and carcinoma CTCs, thus providing a basis for further work to evaluate the clinical potential of CTCs.

Subjects/Keywords: circulating melanoma; non-small cell lung cancer cells; Cancer Biology

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APA (6^th Edition):

Spencer, I. (2020). Characterising PD-L1 expression in circulating melanoma and non-small cell lung cancer cells. (Thesis). Edith Cowan University. Retrieved from https://ro.ecu.edu.au/theses/2318

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Spencer, Isaac. “Characterising PD-L1 expression in circulating melanoma and non-small cell lung cancer cells.” 2020. Thesis, Edith Cowan University. Accessed April 11, 2021. https://ro.ecu.edu.au/theses/2318.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Spencer, Isaac. “Characterising PD-L1 expression in circulating melanoma and non-small cell lung cancer cells.” 2020. Web. 11 Apr 2021.

Vancouver:

Spencer I. Characterising PD-L1 expression in circulating melanoma and non-small cell lung cancer cells. [Internet] [Thesis]. Edith Cowan University; 2020. [cited 2021 Apr 11]. Available from: https://ro.ecu.edu.au/theses/2318.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Spencer I. Characterising PD-L1 expression in circulating melanoma and non-small cell lung cancer cells. [Thesis]. Edith Cowan University; 2020. Available from: https://ro.ecu.edu.au/theses/2318

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Toronto

7. Zaviehgard, Ramin Hamedi. Power Level Control in High-Density Cellular Communication Systems: a Deep Learning Based Approach.

Degree: 2018, University of Toronto

URL: http://hdl.handle.net/1807/95616

►

Effective power control, while essential for the operation of cellular communication systems, is most challenging in high-density cellular systems as the computational complexity for determining… (more)

Subjects/Keywords: Cellular; Deep Learning; Interference; Machine Learning; MIMO; Small Cells; 0459

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APA (6^th Edition):

Zaviehgard, R. H. (2018). Power Level Control in High-Density Cellular Communication Systems: a Deep Learning Based Approach. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/95616

Chicago Manual of Style (16^th Edition):

Zaviehgard, Ramin Hamedi. “Power Level Control in High-Density Cellular Communication Systems: a Deep Learning Based Approach.” 2018. Masters Thesis, University of Toronto. Accessed April 11, 2021. http://hdl.handle.net/1807/95616.

MLA Handbook (7^th Edition):

Zaviehgard, Ramin Hamedi. “Power Level Control in High-Density Cellular Communication Systems: a Deep Learning Based Approach.” 2018. Web. 11 Apr 2021.

Vancouver:

Zaviehgard RH. Power Level Control in High-Density Cellular Communication Systems: a Deep Learning Based Approach. [Internet] [Masters thesis]. University of Toronto; 2018. [cited 2021 Apr 11]. Available from: http://hdl.handle.net/1807/95616.

Council of Science Editors:

Zaviehgard RH. Power Level Control in High-Density Cellular Communication Systems: a Deep Learning Based Approach. [Masters Thesis]. University of Toronto; 2018. Available from: http://hdl.handle.net/1807/95616

University of Manitoba

8. Semasinghe, Lakshika. Distributed resource allocation for self-organizing small cell networks: a game theoretic approach.

Degree: Electrical and Computer Engineering, 2016, University of Manitoba

URL: http://hdl.handle.net/1993/31665

► Future wireless networks are expected to be highly heterogeneous and ultra dense with different types of small cells underlaid with traditional macro cells. In the… (more)

▼ Future wireless networks are expected to be highly heterogeneous and ultra dense with different types of small cells underlaid with traditional macro cells. In the presence of hundreds of different types of small cells, centralized control and manual intervention in network management will be inefficient and expensive. In this case, self-organization has been proposed as a key feature in future wireless networks. In a self-organizing network, the nodes are expected to take individual decisions on their behavior. Therefore, individual decision making in resource allocation (i.e., Distributed Resource Allocation) is of vital important. The objective of this thesis is to develop a distributed resource allocation framework for self-organizing small cell networks. Game theory is a powerful mathematical tool which can model and analyze interactive decision making problems of the agents with conflicting interests. Therefore, it is a well-appropriate tool for modeling the distributed resource allocation problem of small cell networks. In this thesis, I consider three different scenarios of distributed resource allocation in self-organizing small cell networks i.e., i). Distributed downlink power and spectrum allocation to ensure fairness for a small cell network of base stations with bounded rationality, ii). Distributed downlink power control for an ultra dense small cell network of base stations with energy constraints, iii). Distributed joint uplink-downlink power control for a small cell network of possibly deceitful nodes with full-duplexing capabilities. Specifically, I utilize evolutionary games, mean field games, and repeated games to model and analyze the three aforementioned scenarios. I also use stochastic geometry, which is a very powerful mathematical tool that can model the characteristics of the networks with random topologies, to design the payoff functions for the formulated evolutionary game and the mean field game. Advisors/Committee Members: Hossain, Ekram (Electrical and Computer Engineering) (supervisor), Sherif, Sherif (Electrical and Computer Engineering).

Subjects/Keywords: Distributed resource allocation; Game Theory; self-organizing small cells; Wireless Communications

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APA (6^th Edition):

Semasinghe, L. (2016). Distributed resource allocation for self-organizing small cell networks: a game theoretic approach. (Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/31665

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Semasinghe, Lakshika. “Distributed resource allocation for self-organizing small cell networks: a game theoretic approach.” 2016. Thesis, University of Manitoba. Accessed April 11, 2021. http://hdl.handle.net/1993/31665.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Semasinghe, Lakshika. “Distributed resource allocation for self-organizing small cell networks: a game theoretic approach.” 2016. Web. 11 Apr 2021.

Vancouver:

Semasinghe L. Distributed resource allocation for self-organizing small cell networks: a game theoretic approach. [Internet] [Thesis]. University of Manitoba; 2016. [cited 2021 Apr 11]. Available from: http://hdl.handle.net/1993/31665.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Semasinghe L. Distributed resource allocation for self-organizing small cell networks: a game theoretic approach. [Thesis]. University of Manitoba; 2016. Available from: http://hdl.handle.net/1993/31665

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

George Mason University

9. Hamer, Sarah G. The S-nitrosylation of Peroxiredoxin 1 during Bacillus anthracis Infection in Human Small Airway Epithelial Cells .

Degree: 2012, George Mason University

URL: http://hdl.handle.net/1920/7977

► Bacillus anthracis, a Gram-positive soil bacterium, is the causative agent of anthrax. B. anthracis is classified as a “Category A” agent by the Centers for… (more)

Subjects/Keywords: S-nitrosylation; peroxiredoxin 1; human small airway epithelial cells; bacillus anthracis

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APA (6^th Edition):

Hamer, S. G. (2012). The S-nitrosylation of Peroxiredoxin 1 during Bacillus anthracis Infection in Human Small Airway Epithelial Cells . (Thesis). George Mason University. Retrieved from http://hdl.handle.net/1920/7977

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Hamer, Sarah G. “The S-nitrosylation of Peroxiredoxin 1 during Bacillus anthracis Infection in Human Small Airway Epithelial Cells .” 2012. Thesis, George Mason University. Accessed April 11, 2021. http://hdl.handle.net/1920/7977.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Hamer, Sarah G. “The S-nitrosylation of Peroxiredoxin 1 during Bacillus anthracis Infection in Human Small Airway Epithelial Cells .” 2012. Web. 11 Apr 2021.

Vancouver:

Hamer SG. The S-nitrosylation of Peroxiredoxin 1 during Bacillus anthracis Infection in Human Small Airway Epithelial Cells . [Internet] [Thesis]. George Mason University; 2012. [cited 2021 Apr 11]. Available from: http://hdl.handle.net/1920/7977.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Hamer SG. The S-nitrosylation of Peroxiredoxin 1 during Bacillus anthracis Infection in Human Small Airway Epithelial Cells . [Thesis]. George Mason University; 2012. Available from: http://hdl.handle.net/1920/7977

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Rice University

10. Naribole, Sharan. Small Cells and Mobile Clients: a Measurement Study of an Operational Network.

Degree: MS, Engineering, 2014, Rice University

URL: http://hdl.handle.net/1911/88374

► Small cells address the increasing traffic demands from mobile users and target improved coverage and capacity and better quality of experience to users. This thesis… (more)

Subjects/Keywords: small cells; handovers; service quality management; cellular networks

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APA (6^th Edition):

Naribole, S. (2014). Small Cells and Mobile Clients: a Measurement Study of an Operational Network. (Masters Thesis). Rice University. Retrieved from http://hdl.handle.net/1911/88374

Chicago Manual of Style (16^th Edition):

Naribole, Sharan. “Small Cells and Mobile Clients: a Measurement Study of an Operational Network.” 2014. Masters Thesis, Rice University. Accessed April 11, 2021. http://hdl.handle.net/1911/88374.

MLA Handbook (7^th Edition):

Naribole, Sharan. “Small Cells and Mobile Clients: a Measurement Study of an Operational Network.” 2014. Web. 11 Apr 2021.

Vancouver:

Naribole S. Small Cells and Mobile Clients: a Measurement Study of an Operational Network. [Internet] [Masters thesis]. Rice University; 2014. [cited 2021 Apr 11]. Available from: http://hdl.handle.net/1911/88374.

Council of Science Editors:

Naribole S. Small Cells and Mobile Clients: a Measurement Study of an Operational Network. [Masters Thesis]. Rice University; 2014. Available from: http://hdl.handle.net/1911/88374

University of Melbourne

11. Bellmaine, Stephanie Frances. Controlling stem cell fate via chemical inhibition of DYRK kinases.

Degree: 2015, University of Melbourne

URL: http://hdl.handle.net/11343/91430

► A high-throughput screen for small molecules that can enhance the self-renewal of embryonic stem (ES) cells led to the discovery of ID-8, an indole derivative… (more)

Subjects/Keywords: DYRK; human embryonic stem cells; neural differentiation; small molecules; kinase inhibitor

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APA (6^th Edition):

Bellmaine, S. F. (2015). Controlling stem cell fate via chemical inhibition of DYRK kinases. (Doctoral Dissertation). University of Melbourne. Retrieved from http://hdl.handle.net/11343/91430

Chicago Manual of Style (16^th Edition):

Bellmaine, Stephanie Frances. “Controlling stem cell fate via chemical inhibition of DYRK kinases.” 2015. Doctoral Dissertation, University of Melbourne. Accessed April 11, 2021. http://hdl.handle.net/11343/91430.

MLA Handbook (7^th Edition):

Bellmaine, Stephanie Frances. “Controlling stem cell fate via chemical inhibition of DYRK kinases.” 2015. Web. 11 Apr 2021.

Vancouver:

Bellmaine SF. Controlling stem cell fate via chemical inhibition of DYRK kinases. [Internet] [Doctoral dissertation]. University of Melbourne; 2015. [cited 2021 Apr 11]. Available from: http://hdl.handle.net/11343/91430.

Council of Science Editors:

Bellmaine SF. Controlling stem cell fate via chemical inhibition of DYRK kinases. [Doctoral Dissertation]. University of Melbourne; 2015. Available from: http://hdl.handle.net/11343/91430

University of Southern California

12. Rogalin, Ryan. Enabling massive distributed MIMO for small cell networks.

Degree: PhD, Electrical Engineering, 2015, University of Southern California

URL: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/561566/rec/2333

► According to the Cisco Visual Networking Index, the demand for wireless data traffic is expected to increase at an exponential rate for the foreseeable future.… (more)

▼ According to the Cisco Visual Networking Index, the demand for wireless data traffic is expected to increase at an exponential rate for the foreseeable future. This demand is largely driven by the success of smartphones and their de facto killer‐app, mobile video. However, current generation mobile networks are ill‐equipped to meet this demand in very dense user environments such as airports, campuses, conference halls, and stadiums. This problem is fundamentally limited by the quantity of available wireless spectrum, and the efficiency with which this spectrum is used. A novel network architecture known as large‐scale distributed Multiuser MIMO has the potential to solve this impending spectrum crunch. ❧ Large‐scale distributed MU-MIMO unifies two recent trends in wireless research: "massive MIMO" and "small cells." It consists of several Access Points (APs) connected to a central server via a wired backhaul network and which act as a large distributed antenna system. This dissertation presents scalable solutions to the two primary implementation challenges of Distributed MIMO: AP synchronization and uplink/downlink reciprocity calibration. AP synchronization refers to the act of forcing each AP's inexpensive crystal oscillator to operate on the same frequency, as well as the act of forcing each AP to transmit at the same time. Reciprocity calibration refers to the ability to infer downlink (AP to user) channel conditions based on uplink (user to AP) transmissions. The focus of this work is on the downlink, which is both more demanding in terms of traffic and more challenging in terms of implementation than the uplink. All of the proposed synchronization and calibration protocols utilize over‐the‐air signaling, which allows for reduced hardware requirements and for algorithms which scale well with the size of the network. The proposed schemes can be applied to networks formed by a large number of APs, each of which is driven by an inexpensive 802.11-grade clock and has a standard RF front‐end, not explicitly designed to be reciprocal. ❧ In addition to novel synchronization and calibration algorithms, this work presents a number of system‐level optimizations which are needed in practical networks. Experimental and simulation‐based results indicate that a realistic distributed MIMO system is capable of delivering the data rates required by next generation networks. Advisors/Committee Members: Caire, Giuseppe (Committee Chair), Psounis, Konstantinos (Committee Member), Govindan, Ramesh (Committee Member).

Subjects/Keywords: small cells; massive MIMO; multi-user MIMO; basestation cooperation

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APA (6^th Edition):

Rogalin, R. (2015). Enabling massive distributed MIMO for small cell networks. (Doctoral Dissertation). University of Southern California. Retrieved from http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/561566/rec/2333

Chicago Manual of Style (16^th Edition):

Rogalin, Ryan. “Enabling massive distributed MIMO for small cell networks.” 2015. Doctoral Dissertation, University of Southern California. Accessed April 11, 2021. http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/561566/rec/2333.

MLA Handbook (7^th Edition):

Rogalin, Ryan. “Enabling massive distributed MIMO for small cell networks.” 2015. Web. 11 Apr 2021.

Vancouver:

Rogalin R. Enabling massive distributed MIMO for small cell networks. [Internet] [Doctoral dissertation]. University of Southern California; 2015. [cited 2021 Apr 11]. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/561566/rec/2333.

Council of Science Editors:

Rogalin R. Enabling massive distributed MIMO for small cell networks. [Doctoral Dissertation]. University of Southern California; 2015. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/561566/rec/2333

Michigan State University

13. Olds, Daniel P. Refinement of simulated polymer-fullerene photovoltaic devices through small angle scattering and dynamic Monte Carlo.

Degree: 2013, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:505

►

Thesis Ph. D. Michigan State University. Physics 2013.

In order to better understand the effects of morphology on polymer-fullerene based organic photovoltaic devices (OPV), analysis… (more)

Subjects/Keywords: Morphology; Monte Carlo method; Fullerenes; Photovoltaic cells; Small-angle scattering; Physics

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APA (6^th Edition):

Olds, D. P. (2013). Refinement of simulated polymer-fullerene photovoltaic devices through small angle scattering and dynamic Monte Carlo. (Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:505

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Olds, Daniel P. “Refinement of simulated polymer-fullerene photovoltaic devices through small angle scattering and dynamic Monte Carlo.” 2013. Thesis, Michigan State University. Accessed April 11, 2021. http://etd.lib.msu.edu/islandora/object/etd:505.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Olds, Daniel P. “Refinement of simulated polymer-fullerene photovoltaic devices through small angle scattering and dynamic Monte Carlo.” 2013. Web. 11 Apr 2021.

Vancouver:

Olds DP. Refinement of simulated polymer-fullerene photovoltaic devices through small angle scattering and dynamic Monte Carlo. [Internet] [Thesis]. Michigan State University; 2013. [cited 2021 Apr 11]. Available from: http://etd.lib.msu.edu/islandora/object/etd:505.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Olds DP. Refinement of simulated polymer-fullerene photovoltaic devices through small angle scattering and dynamic Monte Carlo. [Thesis]. Michigan State University; 2013. Available from: http://etd.lib.msu.edu/islandora/object/etd:505

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

King Abdullah University of Science and Technology

14. Song, Xin. Performance Evolution of Organic Solar Cells Using Nonfullerene Fused-Ring Electron Acceptors.

Degree: Physical Science and Engineering (PSE) Division, 2019, King Abdullah University of Science and Technology

URL: http://hdl.handle.net/10754/660272

► As one of the most promising solar cell technologies, organic solar cells have unique superiorities distinct from inorganic counterparts, such as semitransparency, flexibility and solution-processability,… (more)

▼ As one of the most promising solar cell technologies, organic solar cells have unique superiorities distinct from inorganic counterparts, such as semitransparency, flexibility and solution-processability, as well as tunable photophysical properties, which originate from the structural verstailities of organic semiconductors. A major breakthrough in OSCs was the exploration of novel non-fullerene electron acceptor (NFAs): In comparison with traditional fullerene derivative acceptors, NFA possesses several advantages, such as low synthesis cost, tunable absorption range and adjustable energetic level, which effectively provides a wide light-harvesting window with low energetic loss. In recent decades, fused-ring electron acceptors (FREAs) have obtained an irreplaceable status in the development of OSCs. However, there are still initial drawbacks to FREA-based devices including: 1: the degree of molecular packing and the corresponding impact on device performance, which has not been studied in depth; 2: the feasibility of approaches for controlling the bulk heterojunction morphology of the film, which also has not been systemic researched; 3: the presence of bulk (geminate and non-geminate) and surface recombination which significantly affects the efficiency and stability of working devices. In this thesis, I took the above three issues as my main doctoral research subjects. In the first part of the thesis, I shine light onto the strength of π-conjugated backbones in FREA molecular structures, which strongly affect the intramolecular interaction. Herein, two FREA with different conjugated framework (IDT core vs IDTT core) are synthesized and employed as electron acceptors in OSCs. A significantly enhanced power conversion efficiency of 11.2% is obtained from IDTTIC-based devices in comparison with that of IDTIC-based devices (5.6%). After considering the electron-donating part in FREA molecules, I also study the effect of the terminal unit, which has a strong relationship with the intramolecular charge transfer effect and intermolecular interactions. Solvent additives are another powerful strategy to further improve the photovoltaic efficiency. 1-chloronaphthalene (CN) was found to be useful in the PTB7-Th:IEICO-4F system, which show a PCE improvement from 9.5% to 12.8%. Furthermore, by utilizing a small molecule donor, BIT-4F-T, as a third component, an optimum PCE of 14.0% is achieved in the devices based on PTB7-Th:IEICO-4F. Advisors/Committee Members: Baran, Derya (advisor), Laquai, Frédéric (committee member), Mohammed, Omar F. (committee member), Yip, Hin-Lap (committee member).

Subjects/Keywords: Organic Solar Cells; fused-ring electron acceptors (FREAs); small molecule

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APA (6^th Edition):

Song, X. (2019). Performance Evolution of Organic Solar Cells Using Nonfullerene Fused-Ring Electron Acceptors. (Thesis). King Abdullah University of Science and Technology. Retrieved from http://hdl.handle.net/10754/660272

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Song, Xin. “Performance Evolution of Organic Solar Cells Using Nonfullerene Fused-Ring Electron Acceptors.” 2019. Thesis, King Abdullah University of Science and Technology. Accessed April 11, 2021. http://hdl.handle.net/10754/660272.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Song, Xin. “Performance Evolution of Organic Solar Cells Using Nonfullerene Fused-Ring Electron Acceptors.” 2019. Web. 11 Apr 2021.

Vancouver:

Song X. Performance Evolution of Organic Solar Cells Using Nonfullerene Fused-Ring Electron Acceptors. [Internet] [Thesis]. King Abdullah University of Science and Technology; 2019. [cited 2021 Apr 11]. Available from: http://hdl.handle.net/10754/660272.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Song X. Performance Evolution of Organic Solar Cells Using Nonfullerene Fused-Ring Electron Acceptors. [Thesis]. King Abdullah University of Science and Technology; 2019. Available from: http://hdl.handle.net/10754/660272

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Illinois – Urbana-Champaign

15. Yen, Jonathan. Materials and biological approach to gene delivery in human embryonic stem cells.

Degree: MS, 0408, 2013, University of Illinois – Urbana-Champaign

URL: http://hdl.handle.net/2142/44809

► Gene delivery is an important tool to study and manipulate human pluripotent stem cells for regenerative medicine purposes. Yet current methods of transient gene delivery… (more)

Subjects/Keywords: Stem Cells; gene delivery; human embryonic stem cells; pluripotent stem cells; peptides; helical peptides; fibroblasts; small molecule

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APA (6^th Edition):

Yen, J. (2013). Materials and biological approach to gene delivery in human embryonic stem cells. (Thesis). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/44809

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Yen, Jonathan. “Materials and biological approach to gene delivery in human embryonic stem cells.” 2013. Thesis, University of Illinois – Urbana-Champaign. Accessed April 11, 2021. http://hdl.handle.net/2142/44809.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Yen, Jonathan. “Materials and biological approach to gene delivery in human embryonic stem cells.” 2013. Web. 11 Apr 2021.

Vancouver:

Yen J. Materials and biological approach to gene delivery in human embryonic stem cells. [Internet] [Thesis]. University of Illinois – Urbana-Champaign; 2013. [cited 2021 Apr 11]. Available from: http://hdl.handle.net/2142/44809.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Yen J. Materials and biological approach to gene delivery in human embryonic stem cells. [Thesis]. University of Illinois – Urbana-Champaign; 2013. Available from: http://hdl.handle.net/2142/44809

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Cambridge

16. Billing, Lawrence. Characterisation of L-cell secretory mechanisms and colonic enteroendocrine cell subpopulations.

Degree: PhD, 2019, University of Cambridge

URL: https://www.repository.cam.ac.uk/handle/1810/290641

► Enteroendocrine cells (EECs) are chemosensitive cells of the gastrointestinal epithelium that exert a wide range of physiological effects via production and secretion of hormones in… (more)

▼ Enteroendocrine cells (EECs) are chemosensitive cells of the gastrointestinal epithelium that exert a wide range of physiological effects via production and secretion of hormones in response to ingested nutrients, bacterial metabolites and systemic signals. Glucagon-like peptide-1 (GLP-1) is one such hormone secreted from so-called L-cells found in both the small and large intestines. GLP-1 exerts an anorexigenic effect and together with glucose- dependent insulinotropic polypeptide (GIP), restores postprandial normoglycaemia through the incretin effect. These effects are exploited by GLP-1 analogues in the treatment of type 2 diabetes. GLP-1 may also contribute to weight-loss and remission of type 2 diabetes following bariatric surgery which increases postprandial GLP-1 excursions. Here we investigated stimulus secretion coupling in L-cells. A novel 2D culture system from murine small intestinal organoids was established as an in vitro model. This was used to characterise synergistic stimulation of GLP-1 secretion in response to concomitant stimulation by bile acids through the Gs-protein coupled receptor GPBAR1 and free fatty acids through the Gq-coupled receptor FFAR1. Roughly half of colonic, but not small intestinal, L-cells co-produce the orexigenic peptide insulin-like peptide 5 (INSL5). This hitherto poorly examined subpopulation of L-cells was characterised through transcriptomic analysis, intracellular calcium imaging (using a novel GCaMP6F-based transgenic mouse model), LC/MS peptide quantification and 3D super resolution microscopy (3D-SIM). Based on the observed prevalent co-storage of GLP-1 and INSL5 in secretory vesicles and similar secretory responses of both hormones to a range of different stimuli strengths (including short chain fatty acids, angiotensin II and arginine vasopressin (AVP)) it was concluded that GLP-1 and INSL5 are co-secreted, rather than being selectively recruited by different stimuli. To further characterise the diversity of colonic EECs, single cell RNA-sequencing (scRNA-seq) was performed on cells isolated from mice with a pan-EEC fluorescent marker (NeuroD1- Cre:Rosa26-EYFP). This illustrated that INSL5-producing L-cells form one of two transcriptomically distinct subpopulations of L-cells in the murine colon, with the other distinguished by expression of neurotensin (Nts). Another major EEC subpopulation, enterochromaffin (EC) cells could be split into three groups, mechanosensitive and pro- inflammatory EC cells distinguished by Piezo2 and Tac1 expression, respectively and a third Sct-expressing group. Immunofluorescent labelling and RT-qPCR analysis revealed that the Nts-expressing and Insl5-expressing L-cell subpopulations are proximally and distally enriched in the murine colon, respectively. In primary cultures, angiotensin II and AVP stimulated INSL5, GLP-1 and PYY but not NTS secretion, correlating with selective expression profiles of the cognate receptors in the L-cell subpopulations. In summary, the work presented suggests that different L-cell subpopulations…

Subjects/Keywords: INSL5; GLP-1; Enteroendocrine cells; Intestinal Organoids; scRNA-seq; L-cells; Gut peptides; Diabetes; Obesity; Colon; Small intestine; Neurotensin

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APA (6^th Edition):

Billing, L. (2019). Characterisation of L-cell secretory mechanisms and colonic enteroendocrine cell subpopulations. (Doctoral Dissertation). University of Cambridge. Retrieved from https://www.repository.cam.ac.uk/handle/1810/290641

Chicago Manual of Style (16^th Edition):

Billing, Lawrence. “Characterisation of L-cell secretory mechanisms and colonic enteroendocrine cell subpopulations.” 2019. Doctoral Dissertation, University of Cambridge. Accessed April 11, 2021. https://www.repository.cam.ac.uk/handle/1810/290641.

MLA Handbook (7^th Edition):

Billing, Lawrence. “Characterisation of L-cell secretory mechanisms and colonic enteroendocrine cell subpopulations.” 2019. Web. 11 Apr 2021.

Vancouver:

Billing L. Characterisation of L-cell secretory mechanisms and colonic enteroendocrine cell subpopulations. [Internet] [Doctoral dissertation]. University of Cambridge; 2019. [cited 2021 Apr 11]. Available from: https://www.repository.cam.ac.uk/handle/1810/290641.

Council of Science Editors:

Billing L. Characterisation of L-cell secretory mechanisms and colonic enteroendocrine cell subpopulations. [Doctoral Dissertation]. University of Cambridge; 2019. Available from: https://www.repository.cam.ac.uk/handle/1810/290641

University of Edinburgh

17. Fakidis, Ioannis. Optical wireless energy transfer for self-sufficient small cells.

Degree: PhD, 2017, University of Edinburgh

URL: http://hdl.handle.net/1842/28946

► Wireless backhaul communication and power transfer can make the deployment of outdoor small cells (SCs) more cost effective; thus, their rapid densification can be enabled.… (more)

▼ Wireless backhaul communication and power transfer can make the deployment of outdoor small cells (SCs) more cost effective; thus, their rapid densification can be enabled. For the first time, solar cells can be leveraged for the two-fold function of energy harvesting (EH) and high speed optical wireless communication. In this thesis, two complementary concepts for power provision to SCs are researched using solar cells – the optical wireless power transfer (OWPT) in the nighttime and solar EH during daytime. A harvested power of 1W is considered to be required for an autonomous SC operation. The conditions of darkness – worst case scenario – are initially selected, because the SC needs to harvest power in the absence of ambient light. The best case scenario of daytime SC EH from sunlight is then explored to determine the required battery size and the additional power from optical sources. As a first approach, an indoor 5m experimental link is created using a white light-emitting diode for OWPT to an amorphous silicon (Si) solar panel. Despite the use of a large mirror for collimation, the harvested power and energy efficiency of the link are measured to be only 18:3mW and 0:1%, respectively. Up to five red laser diodes (LDs) with lenses and crystalline Si (c-Si) cells are used in a follow-up study to increase the link efficiency. A maximum power efficiency of 3:2% is measured for a link comprising two LDs and a mono-c-Si cell, and the efficiency of all of its components is determined. Also, the laser system is shown to achieve an improvement of the energy efficiency by 2:7 times compared with a state-of-the-art inductive power transfer system with dipole coils. Since the harvested power is only 25:7mW, an analytical model for an elliptical Gaussian beam is developed to determine the required number of LDs for harvesting 1W; this shows an estimated number of 61 red LDs with 50mW of output optical power per device. However, a beam enclosure of the developed Class 3B laser system of up to a 3:6m distance is required for eye safety. A simulation study is conducted in Zemax for the design of an outdoor 100m infrared wireless link able to harvest 1W under clear weather conditions. Harvesting 1:2W and meeting eye safety regulations for Class 1 are shown to be feasible by a 1550 nm laser link. The required number of laser power converters is estimated to be 47 with an area of 5 5mm2 per device. Also, the dimensions of the transmitter and receiver are considered to be acceptable for the practical application of SC EH. In the last part of this thesis, two multi-c-Si solar panels are initially used for EH in an outdoor environment during daytime. The power supply of at least 1W is shown to be achievable during hour periods under sunny and cloudy conditions. A maximum average power of 4:1W is measured in the partial presence of clouds using a 10W solar panel. Since the variability of weather conditions induces the harvested power to fluctuate with values of mW, the use of optical sources is required in periods of insufficient…

Subjects/Keywords: small cells; energy harvesting; wireless power transfer; silicon solar cells; laser diodes; laser power converters; Zemax

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APA (6^th Edition):

Fakidis, I. (2017). Optical wireless energy transfer for self-sufficient small cells. (Doctoral Dissertation). University of Edinburgh. Retrieved from http://hdl.handle.net/1842/28946

Chicago Manual of Style (16^th Edition):

Fakidis, Ioannis. “Optical wireless energy transfer for self-sufficient small cells.” 2017. Doctoral Dissertation, University of Edinburgh. Accessed April 11, 2021. http://hdl.handle.net/1842/28946.

MLA Handbook (7^th Edition):

Fakidis, Ioannis. “Optical wireless energy transfer for self-sufficient small cells.” 2017. Web. 11 Apr 2021.

Vancouver:

Fakidis I. Optical wireless energy transfer for self-sufficient small cells. [Internet] [Doctoral dissertation]. University of Edinburgh; 2017. [cited 2021 Apr 11]. Available from: http://hdl.handle.net/1842/28946.

Council of Science Editors:

Fakidis I. Optical wireless energy transfer for self-sufficient small cells. [Doctoral Dissertation]. University of Edinburgh; 2017. Available from: http://hdl.handle.net/1842/28946

University of Florida

18. Fitzpatrick, Daniel M. Escape from Short-Interfering RNA-Induced Silencing in an Orthobunyavirus, Tensaw Virus.

Degree: MS, Entomology and Nematology, 2013, University of Florida

URL: https://ufdc.ufl.edu/UFE0045564

► Ribonucleic acid interference (RNAi) is a major component of antiviral immunity in dipteran insects, including mosquitoes. Virus-specific short-interfering RNA (siRNA) are being considered as a… (more)

Subjects/Keywords: Antivirals; Cell growth; Hela cells; Infections; Nonsense; RNA; RNA interference; Small interfering RNA; Vero cells; Viruses; arbovirus – entomology – mosquito – rnai – virus

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APA (6^th Edition):

Fitzpatrick, D. M. (2013). Escape from Short-Interfering RNA-Induced Silencing in an Orthobunyavirus, Tensaw Virus. (Masters Thesis). University of Florida. Retrieved from https://ufdc.ufl.edu/UFE0045564

Chicago Manual of Style (16^th Edition):

Fitzpatrick, Daniel M. “Escape from Short-Interfering RNA-Induced Silencing in an Orthobunyavirus, Tensaw Virus.” 2013. Masters Thesis, University of Florida. Accessed April 11, 2021. https://ufdc.ufl.edu/UFE0045564.

MLA Handbook (7^th Edition):

Fitzpatrick, Daniel M. “Escape from Short-Interfering RNA-Induced Silencing in an Orthobunyavirus, Tensaw Virus.” 2013. Web. 11 Apr 2021.

Vancouver:

Fitzpatrick DM. Escape from Short-Interfering RNA-Induced Silencing in an Orthobunyavirus, Tensaw Virus. [Internet] [Masters thesis]. University of Florida; 2013. [cited 2021 Apr 11]. Available from: https://ufdc.ufl.edu/UFE0045564.

Council of Science Editors:

Fitzpatrick DM. Escape from Short-Interfering RNA-Induced Silencing in an Orthobunyavirus, Tensaw Virus. [Masters Thesis]. University of Florida; 2013. Available from: https://ufdc.ufl.edu/UFE0045564

University of Hong Kong

19. Chen, Chun-hang. The role of miR-101 and miR-135a in reprogramming of somatic cells into induced pluripotent stem cells.

Degree: 2012, University of Hong Kong

URL: http://hdl.handle.net/10722/193063

► The groundbreaking use of transcription factors (Oct4, Sox2, Klf4, c-Myc) in reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) provides novel ways in… (more)

▼ The groundbreaking use of transcription factors (Oct4, Sox2, Klf4, c-Myc) in reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) provides novel ways in regenerative medicine and disease modeling. The reprogramming process is a stepwise process involving global epigenetic remodeling. In recent years, small molecules like DNA methyltransferase inhibitor that alter the epigenetic status of cells were shown to enhance the reprogramming efficiency. It was postulated that chromatin modifying enzymes played an important role during the reprogramming process, and microRNAs (miRNAs) were the upstream regulators. The objectives of this study involve the identification of potential miRNAs regulating the expression of chromatin modifying enzymes and the study of their roles during reprogramming. Primary mouse embryonic fibroblasts (1o MEFs) were used for the establishment of a reprogramming system, where the delivery of transcription factors Oct4, Sox2, klf4 and cMyc was mediated by lentivirus. Another established secondary MEFs (2o MEFs) reprogramming system was also included in the study. Mouse iPSCs (miPSCs) derived from both systems were shown to express pluripotent markers. In-silico analysis predicted a set of miRNAs (miR-101, miR-135a, miR-148a and miR-148b) commonly targeted the chromatin modifying enzymes in mouse genome. Among them, miR-101 and miR-135a overexpression were found to inhibit the reprogramming efficiency significantly in both 1o and 2o MEFs. Conversely, the inhibition of miR-135a but not miR-101 expression significantly enhanced the reprogramming efficiency in both systems. In this study, it was postulated that miR-101 regulated enhancer of zeste homolog 2 (Ezh2) during reprogramming. Ezh2 was confirmed to be negatively regulated by miR-101 at protein level. The expression of Ezh2 was high in mouse embryonic stem cells (mESCs) but time dependently depressed during mESC differentiation, while its expression was increased during reprogramming of MEFs. Ezh2 expression was found to negatively correlate with miR-101 expression in these conditions. In addition, the knockdown of Ezh2 mimicked the inhibitory effect of miR-101 overexpression on reprogramming efficiency. The inhibitory role of miR-135a on reprogramming was linked to its potential target, Sirtuin 1 (Sirt1). Sirt1 was negatively regulated by miR-135a. The expression of miR-135a was upregulated upon mESC differentiation and decreased during reprogramming. Together with the previous finding in this laboratory, miR-135a expression was negatively correlated with Sirt1. Furthermore, miR-135a inhibition increased the proliferation rate of MEFs. More importantly, miPSCs reprogrammed from miR-135a knockdown MEFs maintained the pluripotent state. To further analyze the pluripotency of the miPSCs, the tetraploid complementation assay was established. Preliminary studies were performed to optimize the conditions for electrofusion. Although single electrofusion with a lower field strength (1000V/cm) resulted in lower fusion…

Subjects/Keywords: Somatic cells; Stem cells; Small interfering RNA

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APA (6^th Edition):

Chen, C. (2012). The role of miR-101 and miR-135a in reprogramming of somatic cells into induced pluripotent stem cells. (Thesis). University of Hong Kong. Retrieved from http://hdl.handle.net/10722/193063

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Chen, Chun-hang. “The role of miR-101 and miR-135a in reprogramming of somatic cells into induced pluripotent stem cells.” 2012. Thesis, University of Hong Kong. Accessed April 11, 2021. http://hdl.handle.net/10722/193063.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Chen, Chun-hang. “The role of miR-101 and miR-135a in reprogramming of somatic cells into induced pluripotent stem cells.” 2012. Web. 11 Apr 2021.

Vancouver:

Chen C. The role of miR-101 and miR-135a in reprogramming of somatic cells into induced pluripotent stem cells. [Internet] [Thesis]. University of Hong Kong; 2012. [cited 2021 Apr 11]. Available from: http://hdl.handle.net/10722/193063.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Chen C. The role of miR-101 and miR-135a in reprogramming of somatic cells into induced pluripotent stem cells. [Thesis]. University of Hong Kong; 2012. Available from: http://hdl.handle.net/10722/193063

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Cambridge

20. Billing, Lawrence. Characterisation of L-cell secretory mechanisms and colonic enteroendocrine cell subpopulations.

Degree: PhD, 2019, University of Cambridge

URL: https://doi.org/10.17863/CAM.37850 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.774620

► Enteroendocrine cells (EECs) are chemosensitive cells of the gastrointestinal epithelium that exert a wide range of physiological effects via production and secretion of hormones in… (more)

▼ Enteroendocrine cells (EECs) are chemosensitive cells of the gastrointestinal epithelium that exert a wide range of physiological effects via production and secretion of hormones in response to ingested nutrients, bacterial metabolites and systemic signals. Glucagon-like peptide-1 (GLP-1) is one such hormone secreted from so-called L-cells found in both the small and large intestines. GLP-1 exerts an anorexigenic effect and together with glucose- dependent insulinotropic polypeptide (GIP), restores postprandial normoglycaemia through the incretin effect. These effects are exploited by GLP-1 analogues in the treatment of type 2 diabetes. GLP-1 may also contribute to weight-loss and remission of type 2 diabetes following bariatric surgery which increases postprandial GLP-1 excursions. Here we investigated stimulus secretion coupling in L-cells. A novel 2D culture system from murine small intestinal organoids was established as an in vitro model. This was used to characterise synergistic stimulation of GLP-1 secretion in response to concomitant stimulation by bile acids through the Gs-protein coupled receptor GPBAR1 and free fatty acids through the Gq-coupled receptor FFAR1. Roughly half of colonic, but not small intestinal, L-cells co-produce the orexigenic peptide insulin-like peptide 5 (INSL5). This hitherto poorly examined subpopulation of L-cells was characterised through transcriptomic analysis, intracellular calcium imaging (using a novel GCaMP6F-based transgenic mouse model), LC/MS peptide quantification and 3D super resolution microscopy (3D-SIM). Based on the observed prevalent co-storage of GLP-1 and INSL5 in secretory vesicles and similar secretory responses of both hormones to a range of different stimuli strengths (including short chain fatty acids, angiotensin II and arginine vasopressin (AVP)) it was concluded that GLP-1 and INSL5 are co-secreted, rather than being selectively recruited by different stimuli. To further characterise the diversity of colonic EECs, single cell RNA-sequencing (scRNA-seq) was performed on cells isolated from mice with a pan-EEC fluorescent marker (NeuroD1- Cre:Rosa26-EYFP). This illustrated that INSL5-producing L-cells form one of two transcriptomically distinct subpopulations of L-cells in the murine colon, with the other distinguished by expression of neurotensin (Nts). Another major EEC subpopulation, enterochromaffin (EC) cells could be split into three groups, mechanosensitive and pro- inflammatory EC cells distinguished by Piezo2 and Tac1 expression, respectively and a third Sct-expressing group. Immunofluorescent labelling and RT-qPCR analysis revealed that the Nts-expressing and Insl5-expressing L-cell subpopulations are proximally and distally enriched in the murine colon, respectively. In primary cultures, angiotensin II and AVP stimulated INSL5, GLP-1 and PYY but not NTS secretion, correlating with selective expression profiles of the cognate receptors in the L-cell subpopulations. In summary, the work presented suggests that different L-cell subpopulations exist…

Subjects/Keywords: INSL5; GLP-1; Enteroendocrine cells; Intestinal Organoids; scRNA-seq; L-cells; Gut peptides; Diabetes; Obesity; Colon; Small intestine; Neurotensin

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APA (6^th Edition):

Billing, L. (2019). Characterisation of L-cell secretory mechanisms and colonic enteroendocrine cell subpopulations. (Doctoral Dissertation). University of Cambridge. Retrieved from https://doi.org/10.17863/CAM.37850 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.774620

Chicago Manual of Style (16^th Edition):

Billing, Lawrence. “Characterisation of L-cell secretory mechanisms and colonic enteroendocrine cell subpopulations.” 2019. Doctoral Dissertation, University of Cambridge. Accessed April 11, 2021. https://doi.org/10.17863/CAM.37850 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.774620.

MLA Handbook (7^th Edition):

Billing, Lawrence. “Characterisation of L-cell secretory mechanisms and colonic enteroendocrine cell subpopulations.” 2019. Web. 11 Apr 2021.

Vancouver:

Billing L. Characterisation of L-cell secretory mechanisms and colonic enteroendocrine cell subpopulations. [Internet] [Doctoral dissertation]. University of Cambridge; 2019. [cited 2021 Apr 11]. Available from: https://doi.org/10.17863/CAM.37850 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.774620.

Council of Science Editors:

Billing L. Characterisation of L-cell secretory mechanisms and colonic enteroendocrine cell subpopulations. [Doctoral Dissertation]. University of Cambridge; 2019. Available from: https://doi.org/10.17863/CAM.37850 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.774620

UCLA

21. Richard, Eric Thomas. Design and Synthesis of Conjugated Polymers and Small Molecules Based on Thiophene-Substituted Isoindigo, 5-acetyl-4H- cyclopenta[c]thiophene-4,6(5H)-dione, and Diketopyrrolopyrrole Electron-Deficient Units.

Degree: Materials Science and Engineering, 2014, UCLA

URL: http://www.escholarship.org/uc/item/503427m3

► Pi-Conjugated polymers and small molecules are useful for their semiconductor properties in organic electronic devices such as organic photovoltaics, light emitting diodes, and thin film… (more)

Subjects/Keywords: Materials Science; Chemistry; Alternative energy; Conjugated Polymers; Organic Electronics; Organic Photovoltaics; Small Molecules; Solar Cells

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APA (6^th Edition):

Richard, E. T. (2014). Design and Synthesis of Conjugated Polymers and Small Molecules Based on Thiophene-Substituted Isoindigo, 5-acetyl-4H- cyclopenta[c]thiophene-4,6(5H)-dione, and Diketopyrrolopyrrole Electron-Deficient Units. (Thesis). UCLA. Retrieved from http://www.escholarship.org/uc/item/503427m3

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Richard, Eric Thomas. “Design and Synthesis of Conjugated Polymers and Small Molecules Based on Thiophene-Substituted Isoindigo, 5-acetyl-4H- cyclopenta[c]thiophene-4,6(5H)-dione, and Diketopyrrolopyrrole Electron-Deficient Units.” 2014. Thesis, UCLA. Accessed April 11, 2021. http://www.escholarship.org/uc/item/503427m3.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Richard, Eric Thomas. “Design and Synthesis of Conjugated Polymers and Small Molecules Based on Thiophene-Substituted Isoindigo, 5-acetyl-4H- cyclopenta[c]thiophene-4,6(5H)-dione, and Diketopyrrolopyrrole Electron-Deficient Units.” 2014. Web. 11 Apr 2021.

Vancouver:

Richard ET. Design and Synthesis of Conjugated Polymers and Small Molecules Based on Thiophene-Substituted Isoindigo, 5-acetyl-4H- cyclopenta[c]thiophene-4,6(5H)-dione, and Diketopyrrolopyrrole Electron-Deficient Units. [Internet] [Thesis]. UCLA; 2014. [cited 2021 Apr 11]. Available from: http://www.escholarship.org/uc/item/503427m3.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Richard ET. Design and Synthesis of Conjugated Polymers and Small Molecules Based on Thiophene-Substituted Isoindigo, 5-acetyl-4H- cyclopenta[c]thiophene-4,6(5H)-dione, and Diketopyrrolopyrrole Electron-Deficient Units. [Thesis]. UCLA; 2014. Available from: http://www.escholarship.org/uc/item/503427m3

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Wolverhampton

22. Butcher, Kate. In vitro and in vivo investigation of the anticancer activity and molecular mechanisms of disulfiram in non-small cell lung cancer.

Degree: PhD, 2019, University of Wolverhampton

URL: http://hdl.handle.net/2436/623026

► Background: This study aims to repurpose disulfiram (DS), a drug used to treat alcohol dependence, into an effective treatment for non-small cell lung cancer (NSCLC).… (more)

▼ Background: This study aims to repurpose disulfiram (DS), a drug used to treat alcohol dependence, into an effective treatment for non-small cell lung cancer (NSCLC). Lung cancer is the leading cause of cancer related death worldwide because of early metastasis and chemoresistance. Cancer stem cells (CSCs) play a key role in chemoresistance and metastasis. Our previous studies indicate that tumour hypoxia induced activation of the nuclear factor-κB (NF-κB) pathway; a pivotal regulator of CSCs. Therefore, development of an NF-κB and CSC targeting drug will improve NSCLC therapeutic outcomes. New drug development is an expensive and time-consuming procedure. DS demonstrates excellent in vitro anti-CSC activity in a wide range of cancers. Cytotoxicity of DS is copper (II) (Cu)-dependent. DS/Cu induces reactive oxygen species and inhibits NF-κB activity, leading cancer cells into apoptosis. The clinical application of DS as an anticancer drug is impeded by its very short half-life in the bloodstream (< 2 minutes). To improve the drug delivery efficiency, we developed a poly lactic-co-glycolic formulation of DS (DS-PLGA), which demonstrates strong anti-cancer efficacy in NSCLC xenograft mouse models. Results: Spheroid and hypoxic cultured cells expressed high levels of CSC markers and were resistant to first- and second-line NSCLC anticancer drugs (doxorubicin, oxaliplatin, paclitaxel and gemcitabine). High NF-κB expression was detected in spheroid and hypoxia cultured NSCLC cell lines. After transfection with p65 subunit of NF-κB, A549 cells expressed CSC markers and became resistant to a wide range of anticancer drugs. DS (5-10 nM) supplemented with Cu (10 μM) induced cytotoxicity to hypoxic cultured NSCLC cells, DS (1 μM) in combination with Cu inhibited sphere reformation. DS/Cu effectively inhibited NF-κB activity, abolished the CSC population and was shown to synergistically enhance the cytotoxicity of the above conventional anti-NSCLC drugs with combination index (CI) values less than 1. The study also shows that protection of the thiuram structure of DS is vital for its cytotoxicity and DS-PLGA extends the half-life of free DS in the bloodstream from 2 minutes to 7 hours. Intravenous injection of DS-PLGA in combination with oral Cu can effectively target NSCLC xenografts in orthotopic and subcutaneous mouse models. Conclusion: DS/Cu specifically inhibits NF-κB pathway and targets CSCs in NSCLC cell lines. PLGA encapsulation improves delivery of DS which demonstrated very strong anticancer activity in NSCLC xenografts in vivo.

Subjects/Keywords: disulfiram; non-small cell lung cancer; chemoresistance; cancer stem cells; hypoxia; NF-?B

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APA (6^th Edition):

Butcher, K. (2019). In vitro and in vivo investigation of the anticancer activity and molecular mechanisms of disulfiram in non-small cell lung cancer. (Doctoral Dissertation). University of Wolverhampton. Retrieved from http://hdl.handle.net/2436/623026

Chicago Manual of Style (16^th Edition):

Butcher, Kate. “In vitro and in vivo investigation of the anticancer activity and molecular mechanisms of disulfiram in non-small cell lung cancer.” 2019. Doctoral Dissertation, University of Wolverhampton. Accessed April 11, 2021. http://hdl.handle.net/2436/623026.

MLA Handbook (7^th Edition):

Butcher, Kate. “In vitro and in vivo investigation of the anticancer activity and molecular mechanisms of disulfiram in non-small cell lung cancer.” 2019. Web. 11 Apr 2021.

Vancouver:

Butcher K. In vitro and in vivo investigation of the anticancer activity and molecular mechanisms of disulfiram in non-small cell lung cancer. [Internet] [Doctoral dissertation]. University of Wolverhampton; 2019. [cited 2021 Apr 11]. Available from: http://hdl.handle.net/2436/623026.

Council of Science Editors:

Butcher K. In vitro and in vivo investigation of the anticancer activity and molecular mechanisms of disulfiram in non-small cell lung cancer. [Doctoral Dissertation]. University of Wolverhampton; 2019. Available from: http://hdl.handle.net/2436/623026

Universidade Federal de Viçosa

23. Daniel Raul Santurio Basile. Morfologia, imuno-histoquímica e aspectos ultraestruturais das células imunorreativas à insulina no intestino delgado do gambá Didelphis aurita (Wied-Neuwied, 1826) adulto.

Degree: 2011, Universidade Federal de Viçosa

URL: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=3545

►

Esta pesquisa teve como objetivo geral descrever os aspectos morfológicos, histoquímicos e imuno-histoquímicos do intestino delgado do gambá Didelphis aurita (Wied-Neuwied, 1826) adulto, bem como… (more)

▼

Esta pesquisa teve como objetivo geral descrever os aspectos morfológicos, histoquímicos e imuno-histoquímicos do intestino delgado do gambá Didelphis aurita (Wied-Neuwied, 1826) adulto, bem como as características ultraestruturais dos grânulos secretores de células imunorreativas à insulina nesse animal. A biogênese dos grânulos insulínicos e a sua classificação, bem como a atividade fisiológica em regiões produtoras de insulina, são áreas de investigação contínua no controle do diabetes e outras patologias. O material para estudo consistiu de sete exemplares de gambá Didelphis aurita, machos, com peso médio de 1,03 0,14 kg. O número de células imunorreativas à insulina (IRI) por mm2 no intestino delgado dos gambás D. aurita foi diferente em função do segmento analisado. De acordo com a comparação múltipla de médias ordenadas, o número de células IRI por mm2 no duodeno e no jejuno foi maior do que no íleo (p<0,05). O intestino delgado do gambá adulto D. aurita apresentou diferenças na distribuição das células IRI, sendo elas difusas ao longo do epitélio intestinal e com maior concentração nas criptas e redução nas vilosidades. As células IRI caracterizaram-se pela presença de grânulos secretores, pela morfologia piramidal alongada e pela localização entre diferentes células. Adicionalmente, foi possível afirmar que apresentaram morfologia similar à das células beta do pâncreas, porém com diâmetro e volume granular maiores. Nos gambás Didelphis aurita, foram observados valores entre 2,7 e 3,5 μIU/mL de insulina plasmática, valores esses inferiores aos verificados em outros mamíferos e humanos. Os resultados em relação à insulinemia, nesta espécie, sugerem a manutenção da homeostasia da glicose mediante a atividade secretora insulínica extrapancreática. Nos estudos morfológicos e histoquímicos das células argirófilas e argentafins no intestino delgado, foi demonstrado que as células argirófilas eram mais numerosas em relação às argentafins e que ambas se caracterizavam por terem conformação piramidal e núcleo ovoide, serem do tipo fechado ou aberto, apresentarem aspecto granular e serem mais frequentes nas glândulas intestinais. Foi quantificado maior número de células argirófilas por mm2 do que de argentafins, e o íleo foi o segmento com menor número total de células endócrinas quantificadas. A altura e espessura das vilosidades intestinais, bem como a densidade da área de absorção do epitélio intestinal dos gambás D. aurita adultos, não variaram entre os segmentos. A espessura da camada muscular circular do jejuno foi maior do que a do íleo, e as demais comparações não apresentaram diferenças morfológicas significativas.

This research had as its objective to describe the morphologic, histochemical and immunohistochemical aspects of the small intestine of the opossum Didelphis aurita (Wied-Neuwied, 1826) adult, as well as the ultrastructural characterisitics of the secretory granules of insuline immunoreactive cells in this animal. The biogenesis of insulin granules and its classification, as well as…

Advisors/Committee Members: Cláudio César Fonseca, Sérgio Luis Pinto da Matta, Clóvis Andrade Neves, Tânia Toledo de Oliveira, Sirlene Souza Rodrigues Sartori, Ita de Oliveira e Silva, Carlos Alberto Mourão Júnior.

Subjects/Keywords: BIOLOGIA GERAL; Células imunorreativas; Insulina; Intestino delgado; Gambá; Immunoreactive cells; Insulin; Small intestine; Opossum

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Basile, D. R. S. (2011). Morfologia, imuno-histoquímica e aspectos ultraestruturais das células imunorreativas à insulina no intestino delgado do gambá Didelphis aurita (Wied-Neuwied, 1826) adulto. (Thesis). Universidade Federal de Viçosa. Retrieved from http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=3545

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Basile, Daniel Raul Santurio. “Morfologia, imuno-histoquímica e aspectos ultraestruturais das células imunorreativas à insulina no intestino delgado do gambá Didelphis aurita (Wied-Neuwied, 1826) adulto.” 2011. Thesis, Universidade Federal de Viçosa. Accessed April 11, 2021. http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=3545.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Basile, Daniel Raul Santurio. “Morfologia, imuno-histoquímica e aspectos ultraestruturais das células imunorreativas à insulina no intestino delgado do gambá Didelphis aurita (Wied-Neuwied, 1826) adulto.” 2011. Web. 11 Apr 2021.

Vancouver:

Basile DRS. Morfologia, imuno-histoquímica e aspectos ultraestruturais das células imunorreativas à insulina no intestino delgado do gambá Didelphis aurita (Wied-Neuwied, 1826) adulto. [Internet] [Thesis]. Universidade Federal de Viçosa; 2011. [cited 2021 Apr 11]. Available from: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=3545.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Basile DRS. Morfologia, imuno-histoquímica e aspectos ultraestruturais das células imunorreativas à insulina no intestino delgado do gambá Didelphis aurita (Wied-Neuwied, 1826) adulto. [Thesis]. Universidade Federal de Viçosa; 2011. Available from: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=3545

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

24. Wright, George. Electrophysiology of interstitial cells of Cajal.

Degree: PhD, 2017, McMaster University

URL: http://hdl.handle.net/11375/21233

►

This thesis focuses on elucidating the electrical mechanisms underlying excitation of small intestinal and colonic smooth muscle initiated by interstitial cells of Cajal (ICC). All… (more)

▼

This thesis focuses on elucidating the electrical mechanisms underlying excitation of small intestinal and colonic smooth muscle initiated by interstitial cells of Cajal (ICC). All the ICC subtypes are involved in the orchestration, generation, and/or transmission of electrical signals to smooth muscle to pace gut motor patterns. Some ICC types have intrinsic activity leading to omnipresent rhythmic changes in smooth muscle excitability; others respond to stimuli, inducing pacemaker activity as required. Together they orchestrate motor patterns such as propulsion and segmentation, essential functions of the gut. To study ICC electrophysiology, I utilized patch clamping to record ion channel currents from single intestinal ICC and sharp microelectrodes to record colonic smooth muscle membrane potentials. I have made several discoveries contributing to our understanding of ICC electrophysiology. Firstly, my research increased our understanding of the properties of intrinsic pace-maker activity. I showed that maxi Cl– channels from small intestinal ICC make a significant contribution to slow wave depolarization triggered by intracellular calcium. Secondly, I showed that colonic intramuscular ICC (ICC-IM) selectively express KV7.5 channels, which are suppressed by cholinergic agonists, meaning that excitatory stimuli triggering acetylcholine release deactivate KV7.5 channels, leading to increased excitability. Thirdly, I have shown that the bile acid chenodeoxycholic acid and the nitric oxide donor sodium ni-troprusside both induce pacemaker activity, rhythmic transient depolarisations in mouse colonic muscle, which led to the hypothesis that nitrergic nerves are involved in generating inducible myenteric plexus ICC (ICC-MP) pacemaker activity. It is only when ICC are suitably stimulated by intracellular processes such as rhythmic Ca2+ transients or extracellular signalling from neurotransmitters or small molecules, that ICC produce membrane potential rhythmicity, required for generation of intrinsic slow waves, low-frequency rhythmic transient depolarisations and transmission of excitation into the muscle.

Thesis

Doctor of Philosophy (PhD)

The gut is essential for digestion and absorption of food. The gut has special cells called interstitial cells of Cajal (ICC), which control the contractions of the gut muscle. ICC are pacemaker cells, like those that pace heart beats. To pace gut muscle contractions, ICC generate electrical signals which cause the muscle to contract in an organized rhythmic manner, which promotes mixing or propulsion of gut contents, called motility. I used tiny electrodes to record electrical activity from ICC or gut muscle, to improve our understanding of how ICC pacemaker activity controls motility. My research characterised ion channels, which are microscopic protein pores that allow cells to make electrical currents, that enable generation of pacemaker signals by ICC. I also investigated activation of ICC electrical activity that causes propulsive colonic motility. This will hopefully…

Advisors/Committee Members: Huizinga, Jan, Medical Sciences (Division of Physiology/Pharmacology).

Subjects/Keywords: Electrophysiology; Interstitial cells of Cajal; Patch clamp; Pharmacology; Pacemaker; Small intestine; Colon

10 more images…

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Wright, G. (2017). Electrophysiology of interstitial cells of Cajal. (Doctoral Dissertation). McMaster University. Retrieved from http://hdl.handle.net/11375/21233

Chicago Manual of Style (16^th Edition):

Wright, George. “Electrophysiology of interstitial cells of Cajal.” 2017. Doctoral Dissertation, McMaster University. Accessed April 11, 2021. http://hdl.handle.net/11375/21233.

MLA Handbook (7^th Edition):

Wright, George. “Electrophysiology of interstitial cells of Cajal.” 2017. Web. 11 Apr 2021.

Vancouver:

Wright G. Electrophysiology of interstitial cells of Cajal. [Internet] [Doctoral dissertation]. McMaster University; 2017. [cited 2021 Apr 11]. Available from: http://hdl.handle.net/11375/21233.

Council of Science Editors:

Wright G. Electrophysiology of interstitial cells of Cajal. [Doctoral Dissertation]. McMaster University; 2017. Available from: http://hdl.handle.net/11375/21233

University of Saskatchewan

25. Fries, Patrick Norbert. Distribution and frequency of myeloid and t cell populations in the small intestine of newborn and weaned calves.

Degree: 2011, University of Saskatchewan

URL: http://hdl.handle.net/10388/etd-07282011-105745

► The development of mucosal dendritic cells (DCs) in cattle is poorly understood and an analysis of myeloid cells in the bovine small intestine is required… (more)

▼ The development of mucosal dendritic cells (DCs) in cattle is poorly understood and an analysis of myeloid cells in the bovine small intestine is required to increase our knowledge in this area. The phenotype, frequency and distribution of mucosal myeloid and lymphoid lamina propria leukocytes (LPL) and intraepithelial leukocytes (IEL) in the ileum and jejunum of newborn calves (3-5 weeks old) were analyzed using flow cytometry and immunohistochemistry (IHC). LPL and IEL were isolated through the use of chemical and enzymatic incubations. Costaining with a CD45-specific monoclonal antibody allowed us to exclude all non-leukocytic cells from our analysis of IEL and LPL. The morphology of CD45+CD11c+MHC Class II+ cells isolated from the lamina propria (LP) of ileum and jejunum showed myeloid characteristics, validating the use of CD11c and MHC Class II co-expression to identify myeloid cells. Regional differences in the frequency and number of leukocytes isolated from the IEL and LP compartments of the ileum and jejunum were analyzed in newborn calves. The CD11cHiCD14+ and CD335+ NK cell populations were significantly more abundant in the ileum than the jejunum. IHC was then used to identify the distribution of myeloid cells within the intestine. This analysis confirmed the presence of a variety of myeloid cell populations within the LP. Furthermore, CD11c+ cells were uniquely distributed within the jejunal, but not the ileal IEL compartment. In contrast, CD11b+ cells were present in the ileal, but absent from the jejunal, IEL compartment. A comparison of myeloid cell populations isolated from jejunum and blood dentified distinct mucosal DC populations, such as CD11c+CD13+ cells, which were present in he jejunum but absent from blood. The phenotype, frequency and distribution of IEL and LPL in the ileum and jejunum of weaned calves (6 months old) were then investigated. Significant regional differences were observed when comparing mucosal T cell populations with CD8+ and γδ T cells more abundant in the ileum and CD4+ T cells more abundant in the jejunum. Proportionally, there were no significant differences between the frequency and number of myeloid populations in the two regions. IHC was, once again, used to confirm these unique distributions of cells within each region. CD11b+ cells were present in the LP of both the ileum and jejunum, although a small number of CD11b+ cells were found in the ileal epithelium. CD4+ T cells were restricted to the LP, while CD8+ and γδ T cells were restricted to the IEL compartment. Significant age-related changes were observed when comparing mucosal leukocyte populations in the ileum and jejunum of newborn and 6 month old calves. In the ileum there was an age-related enrichment of CD8+ and γδ T cells, while in the jejunum there was enrichment in CD4+ and CD8+ T cells. In contrast, total myeloid (CD11c+MHC Class II+) cells number remained unchanged but there was a significant age-related enrichment of DC subpopulations (CD13, CD26, CD205). In… Advisors/Committee Members: Griebel, Philip, Hill, Janet, Qualtiere, Lou, van Kessel, Andrew, Gerdts, Volker.

Subjects/Keywords: lamina propria leukocytes; intraepithelial lymphocytes; dendritic cells; cellular immunology; bovine; small intestine; mucosal immunity

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APA (6^th Edition):

Fries, P. N. (2011). Distribution and frequency of myeloid and t cell populations in the small intestine of newborn and weaned calves. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/etd-07282011-105745

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Fries, Patrick Norbert. “Distribution and frequency of myeloid and t cell populations in the small intestine of newborn and weaned calves.” 2011. Thesis, University of Saskatchewan. Accessed April 11, 2021. http://hdl.handle.net/10388/etd-07282011-105745.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Fries, Patrick Norbert. “Distribution and frequency of myeloid and t cell populations in the small intestine of newborn and weaned calves.” 2011. Web. 11 Apr 2021.

Vancouver:

Fries PN. Distribution and frequency of myeloid and t cell populations in the small intestine of newborn and weaned calves. [Internet] [Thesis]. University of Saskatchewan; 2011. [cited 2021 Apr 11]. Available from: http://hdl.handle.net/10388/etd-07282011-105745.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Fries PN. Distribution and frequency of myeloid and t cell populations in the small intestine of newborn and weaned calves. [Thesis]. University of Saskatchewan; 2011. Available from: http://hdl.handle.net/10388/etd-07282011-105745

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Texas Medical Center

26. de la Cruz Bonilla, Marimar. FASTING REDUCES INTESTINAL RADIOTOXICITY ENABLING DOSE-ESCALATED RADIOTHERAPY FOR PANCREATIC CANCER.

Degree: PhD, 2019, Texas Medical Center

URL: https://digitalcommons.library.tmc.edu/utgsbs_dissertations/969

► Surgical resection is the only potentially curative treatment for pancreatic cancer, but only 15-20% of patients have resectable tumors. In unresectable cases, stereotactic body… (more)

▼ Surgical resection is the only potentially curative treatment for pancreatic cancer, but only 15-20% of patients have resectable tumors. In unresectable cases, stereotactic body radiotherapy (SBRT) may be used to give tumor-directed radiotherapy (RT). Unfortunately, this can cause severe gastrointestinal (GI) toxicity due to proximity of the pancreatic head to the duodenum. Protecting the intestine from the toxic side-effects of radiation may enable dose-escalation that could achieve more effective local control of disease. We and others have previously shown that a fast of 24 hours protects mice from lethal doses of the DNA-damaging agent etoposide. In this study, we demonstrate that a 24 hour fast also protects mice from lethal doses of total-abdominal radiation. Histologic analyses using the Withers-Elkind microcolony assay show that fasting protected small intestinal (SI) stem cells from radiation damage and promoted early regeneration. To show a proof-of-principle for the use of this radioporotective maneuver in cancer therapy, we used an orthotopic model of pancreatic cancer using KPC tumor cells syngeneic to C57BL/6. Here, we show that fasting-mediated intestinal protection enabled dose escalated SBRT for treatment of these orthotopic tumors. RT with fasting-mediated radioprotection delayed tumor growth and improved survival compared to controls. Given this robust phenotype, we developed a 3D culture ex vivo assay using intestinal stem cell-enriched epithelial spheroid cultures. We modified these intestinal spheroids with a bioluminescent reporter and used these cells to develop a modified clonogenic assay for 3D culture that can be used to identify novel radioprotectors, such as a fasting mimetic. Taken together, these results suggest that fasting protects small intestinal stem cells, allowing animals to receive potentially curative doses of abdominal radiation that would otherwise be lethal. Future work will aim to identifying the mechanisms by which fasting confers intestinal protection and drug candidates that can be used to mimic this fasting-mediated protection. Advisors/Committee Members: Helen Piwnica-Worms, Cullen M. Taniguchi, Michelle Barton.

Subjects/Keywords: radiation; small intestine; toxicity; pancreas; pdac; stem cells; fasting; Cancer Biology; Radiation Medicine

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

de la Cruz Bonilla, M. (2019). FASTING REDUCES INTESTINAL RADIOTOXICITY ENABLING DOSE-ESCALATED RADIOTHERAPY FOR PANCREATIC CANCER. (Doctoral Dissertation). Texas Medical Center. Retrieved from https://digitalcommons.library.tmc.edu/utgsbs_dissertations/969

Chicago Manual of Style (16^th Edition):

de la Cruz Bonilla, Marimar. “FASTING REDUCES INTESTINAL RADIOTOXICITY ENABLING DOSE-ESCALATED RADIOTHERAPY FOR PANCREATIC CANCER.” 2019. Doctoral Dissertation, Texas Medical Center. Accessed April 11, 2021. https://digitalcommons.library.tmc.edu/utgsbs_dissertations/969.

MLA Handbook (7^th Edition):

de la Cruz Bonilla, Marimar. “FASTING REDUCES INTESTINAL RADIOTOXICITY ENABLING DOSE-ESCALATED RADIOTHERAPY FOR PANCREATIC CANCER.” 2019. Web. 11 Apr 2021.

Vancouver:

de la Cruz Bonilla M. FASTING REDUCES INTESTINAL RADIOTOXICITY ENABLING DOSE-ESCALATED RADIOTHERAPY FOR PANCREATIC CANCER. [Internet] [Doctoral dissertation]. Texas Medical Center; 2019. [cited 2021 Apr 11]. Available from: https://digitalcommons.library.tmc.edu/utgsbs_dissertations/969.

Council of Science Editors:

de la Cruz Bonilla M. FASTING REDUCES INTESTINAL RADIOTOXICITY ENABLING DOSE-ESCALATED RADIOTHERAPY FOR PANCREATIC CANCER. [Doctoral Dissertation]. Texas Medical Center; 2019. Available from: https://digitalcommons.library.tmc.edu/utgsbs_dissertations/969

27. Ota, Masahide; Mochizuki, Satsuki; Shimoda, Masayuki; Abe, Hitoshi; Miyamae, Yuka; Ishii, Ken; Kimura, Hiroshi. ADAM23 is downregulated in side population and suppresses lung metastasis of lung carcinoma cells. : Side populationにおいて発現抑制されているADAM23は肺癌の転移を抑制している.

Degree: 博士（医学）, 2016, Nara Medical University / 奈良県立医科大学

URL: http://hdl.handle.net/10564/3272

►

Cancer cells contain a small population of cancer stem cells or cancer initiating cells, which can be enriched in the side population (SP) after fluorescence… (more)

▼

Cancer cells contain a small population of cancer stem cells or cancer initiating cells, which can be enriched in the side population (SP) after fluorescence activated cell sorting. To examine the members of the ADAM, ADAMTS and MMP gene families related to phenotypes of the SP and the main population (MP), we screened the expression of all the members in the propagated SP and MP of A549 lung adenocarcinoma cells, and found that the relative expression ratio of ADAM23 in the MP to the SP is most highly increased, but none of them are increased in the SP. A similar result on the ADAM23 expression was obtained with another cell line, Calu-3 cells. Overexpression of ADAM23 inhibited colony formation, cell adhesion and migration, and knockdown of ADAM23 by shRNA showed the reverse effects. ADAM23-mediated suppression of colony formation, cell adhesion and migration was greatly reduced by treatment with neutralizing anti-ADAM23 antibody, anti-αvβ3 integrin antibody and/or ADAM23 disintegrin peptide. Expression of cancer stem cell-related genes, including AKRC1/2, TM4SF1 and NR0B1, was increased by knockdown of ADAM23. In addition, lung metastasis of A549 transfectants with different levels of ADAM23 expression was negatively regulated by the ADAM23 expression levels. Our data provide evidence that ADAM23 plays a role in suppression of cancer cell progression through interaction with αvβ3 integrin, and suggest that downregulation of ADAM23 in SP cells may contribute toward providing a cancer stem cell phenotype by facilitating the activity of integrin αvβ3.

博士（医学）・乙第1382号・平成28年9月28日

This is an open access article under the terms of the Creative CommonsAttribution-NonCommercial-NoDerivs License(https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits use and distributionin any medium, provided the original work is properly cited, the use is noncommercialand no modifications or adaptations are made.

Subjects/Keywords: ADAM23; colony formation; metastasis; non-small cell lung carcinoma cells; side population

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ota, Masahide; Mochizuki, Satsuki; Shimoda, Masayuki; Abe, Hitoshi; Miyamae, Yuka; Ishii, Ken; Kimura, H. (2016). ADAM23 is downregulated in side population and suppresses lung metastasis of lung carcinoma cells. : Side populationにおいて発現抑制されているADAM23は肺癌の転移を抑制している. (Thesis). Nara Medical University / 奈良県立医科大学. Retrieved from http://hdl.handle.net/10564/3272

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ota, Masahide; Mochizuki, Satsuki; Shimoda, Masayuki; Abe, Hitoshi; Miyamae, Yuka; Ishii, Ken; Kimura, Hiroshi. “ADAM23 is downregulated in side population and suppresses lung metastasis of lung carcinoma cells. : Side populationにおいて発現抑制されているADAM23は肺癌の転移を抑制している.” 2016. Thesis, Nara Medical University / 奈良県立医科大学. Accessed April 11, 2021. http://hdl.handle.net/10564/3272.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ota, Masahide; Mochizuki, Satsuki; Shimoda, Masayuki; Abe, Hitoshi; Miyamae, Yuka; Ishii, Ken; Kimura, Hiroshi. “ADAM23 is downregulated in side population and suppresses lung metastasis of lung carcinoma cells. : Side populationにおいて発現抑制されているADAM23は肺癌の転移を抑制している.” 2016. Web. 11 Apr 2021.

Vancouver:

Ota, Masahide; Mochizuki, Satsuki; Shimoda, Masayuki; Abe, Hitoshi; Miyamae, Yuka; Ishii, Ken; Kimura H. ADAM23 is downregulated in side population and suppresses lung metastasis of lung carcinoma cells. : Side populationにおいて発現抑制されているADAM23は肺癌の転移を抑制している. [Internet] [Thesis]. Nara Medical University / 奈良県立医科大学; 2016. [cited 2021 Apr 11]. Available from: http://hdl.handle.net/10564/3272.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ota, Masahide; Mochizuki, Satsuki; Shimoda, Masayuki; Abe, Hitoshi; Miyamae, Yuka; Ishii, Ken; Kimura H. ADAM23 is downregulated in side population and suppresses lung metastasis of lung carcinoma cells. : Side populationにおいて発現抑制されているADAM23は肺癌の転移を抑制している. [Thesis]. Nara Medical University / 奈良県立医科大学; 2016. Available from: http://hdl.handle.net/10564/3272

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

28. Archet, Florence. Cellules solaires organiques à base de molécules bio-inspirées : Bio-inspired small molecules for organic solar cells.

Degree: Docteur es, Electronique, 2018, Bordeaux

URL: http://www.theses.fr/2018BORD0400

►

Face à la croissance de la demande énergétique, les énergies alternatives, telles que l’énergie photovoltaïque, représentent des solutions réalistes. Cette dernière nécessite des matériaux efficaces… (more)

▼

Face à la croissance de la demande énergétique, les énergies alternatives, telles que l’énergie photovoltaïque, représentent des solutions réalistes. Cette dernière nécessite des matériaux efficaces pour la capture des photons et leur conversion en électricité.Les cellules solaires organiques (CSOs) sont basées sur les propriétés semiconductrices de certaines molécules ou de certains polymères π-conjugués. Dans le domaine des CSOs, les efforts de recherche actuels se concentrent selon trois axes : la réduction des coûts, l’augmentation de la durée de vie des cellules solaires et l’augmentation des rendements de conversion photovoltaïque. Les récentsdéveloppements ont conduit à une complexification des architectures des CSOs ainsi que des semi-conducteurs organiques utilisés, induisant une augmentation des coûts de fabrication. Dans une logique de développement économiquement efficace et écologiquement soutenable, il est nécessaire aujourd’hui de se concentrer sur des semi-conducteurs organiques viables économiquement et dont la synthèse est respectueuse de l’environnement. Ce travail doctoral a pour but de développer de nouveaux matériaux semi-conducteurs organiques bio-inspirés et bas coût. Les molécules étudiées présentent une structure donneur-accepteur-donneur. Leur squelette est celui de la curcumine, molécule qui donne sa couleur au curcuma. Le groupement accepteur est un difluorure de bore. Les groupements donneurs quant à eux varient suivant les semi-conducteurs. Les propriétés optoélectroniques de dix-sept dérivés curcuminoïdes ont été étudiées. Plusieurs d’entre eux se sont démarqués : ceux avec des groupements anthracène, ceux avec des dérivés thiophènes, enfin et impact sur les performances photovoltaïques de la formulation de l’encre utilisée pour le dépôt de la couche a été étudié en détail. Différents matériaux accepteurs ont été testés, de même que l’utilisation de mélanges ternaires. Pour l’un de dérivés curcuminoïde en combinaison avec du PC61BM, des rendements supérieurs à 4 % ont été obtenus avec des tensions de circuit ouvert supérieures à 1,0 V. Au regard de la simplicité structurale de ce semi-conducteur, ces résultats figurent à notre connaissance parmi les meilleurs reportés dans la littérature. Les phénomènes photophysiques ont également été étudiés par spectroscopie d’absorption des espèces transitoires. Enfin, le procédé de fabrication a été rapproché des conditions industrielles en éliminant les solvants halogénés utilisés et en travaillant à l’air ambiant. Finalement, bien qu’intéressantes, les propriétés photovoltaïques restent limitées pour une application industrielle du fait de la faible mobilité des trous de ces matériaux.

To face the growing needs in energy, renewable energies like solar photovoltaic represent realistic solutions. Photovoltaic energy requires efficient materials to absorb photons and to convert them into electricity. Organic solar cells (OSCs) are based on semiconducting π-conjugated polymer or small molecules. Current research in this field focuses on three…

Advisors/Committee Members: Wantz, Guillaume (thesis director), Chambon, Sylvain (thesis director), Abbas, Mamatimin (thesis director).

Subjects/Keywords: Cellules solaires organiques; Curcuminonïde; Petites molécules; Organic solar cells; Curcuminoïd; Small molecules

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❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Archet, F. (2018). Cellules solaires organiques à base de molécules bio-inspirées : Bio-inspired small molecules for organic solar cells. (Doctoral Dissertation). Bordeaux. Retrieved from http://www.theses.fr/2018BORD0400

Chicago Manual of Style (16^th Edition):

Archet, Florence. “Cellules solaires organiques à base de molécules bio-inspirées : Bio-inspired small molecules for organic solar cells.” 2018. Doctoral Dissertation, Bordeaux. Accessed April 11, 2021. http://www.theses.fr/2018BORD0400.

MLA Handbook (7^th Edition):

Archet, Florence. “Cellules solaires organiques à base de molécules bio-inspirées : Bio-inspired small molecules for organic solar cells.” 2018. Web. 11 Apr 2021.

Vancouver:

Archet F. Cellules solaires organiques à base de molécules bio-inspirées : Bio-inspired small molecules for organic solar cells. [Internet] [Doctoral dissertation]. Bordeaux; 2018. [cited 2021 Apr 11]. Available from: http://www.theses.fr/2018BORD0400.

Council of Science Editors:

Archet F. Cellules solaires organiques à base de molécules bio-inspirées : Bio-inspired small molecules for organic solar cells. [Doctoral Dissertation]. Bordeaux; 2018. Available from: http://www.theses.fr/2018BORD0400

Edith Cowan University

29. Khan, Mohammad Arifin Rahman. Mobility management in 5G heterogeneous networks.

Degree: 2019, Edith Cowan University

URL: https://ro.ecu.edu.au/theses/2252

► In recent years, mobile data traffic has increased exponentially as a result of widespread popularity and uptake of portable devices, such as smartphones, tablets and… (more)

Subjects/Keywords: Mobility management; small cells; 5G; Electrical and Computer Engineering; Electrical and Electronics; Engineering

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Khan, M. A. R. (2019). Mobility management in 5G heterogeneous networks. (Thesis). Edith Cowan University. Retrieved from https://ro.ecu.edu.au/theses/2252

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Khan, Mohammad Arifin Rahman. “Mobility management in 5G heterogeneous networks.” 2019. Thesis, Edith Cowan University. Accessed April 11, 2021. https://ro.ecu.edu.au/theses/2252.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Khan, Mohammad Arifin Rahman. “Mobility management in 5G heterogeneous networks.” 2019. Web. 11 Apr 2021.

Vancouver:

Khan MAR. Mobility management in 5G heterogeneous networks. [Internet] [Thesis]. Edith Cowan University; 2019. [cited 2021 Apr 11]. Available from: https://ro.ecu.edu.au/theses/2252.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Khan MAR. Mobility management in 5G heterogeneous networks. [Thesis]. Edith Cowan University; 2019. Available from: https://ro.ecu.edu.au/theses/2252

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

30. van der Poll, Thomas Scott. Design, Synthesis and Theoretical Investigation of Small Molecules for Utility in Organic Semiconducting Devices.

Degree: 2014, University of California – eScholarship, University of California

URL: http://www.escholarship.org/uc/item/5n3063xt

► Solution-processed small molecule bulk-heterojunction solar cells represent a specific subset of organic photovoltaics (OPV). OPV devices rely on materials with appropriately aligned frontier molecular orbitals,… (more)

▼ Solution-processed small molecule bulk-heterojunction solar cells represent a specific subset of organic photovoltaics (OPV). OPV devices rely on materials with appropriately aligned frontier molecular orbitals, bandgaps commensurate with the solar spectrum, and ultimately must self-assemble into a morphology conducive to high device performance. Optical electronic and physical properties in organic materials are highly sensitive to their chemical structure and the conformations of those structures in space. Materials can be engineered to exhibit specific traits; a process referred to as "molecular design." While the molecular design toolbox is ever-expanding, each of these properties requires unique considerations, and indeed vary greatly in the degree of control the synthetic chemist has in producing predictable properties. In order to elucidate the relationship between structure and properties, a class of small molecules was developed adhering to what can be described as a D'ADAD' architecture, where D, D' and A refer to an electron rich core, electron rich end-caps and electron deficient heterocyclic fragments, respectively. These fragments, as well as solubilizing side groups were systematically modified, yielding useful design rules for organic donor materials as well as record breaking small-molecule OPV devices. The top performing material in the group exhibited diminutive performance on the ubiquitous solution deposited substrate PEDOT:PSS due to interfacial chemistry. This led to the development of a new material, p-DTS(FBTTh2)2, which was not susceptible to the interfacial chemistry with PEDOT:PSS, and broke the previous performance record for solution-processed small molecule OPV devices. Four isostructural molecules, including p-DTS(FBTTh2)2 were investigated with single crystal x-ray diffraction. While all four molecules appear topologically equivalent, two types of crystal structure were observed with distinct crystal systems and each with a characteristic molecular geometry. A multi-scale theoretical investigation of simulated isolated molecules and experimentally determined crystal structures offers a clear explanation for the observed lattices, where useful experimental data is unavailable.

Subjects/Keywords: Chemistry; Materials Science; Density Functional Theory; Organic; Small Molecules; Solar Cells; Synthesis

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

van der Poll, T. S. (2014). Design, Synthesis and Theoretical Investigation of Small Molecules for Utility in Organic Semiconducting Devices. (Thesis). University of California – eScholarship, University of California. Retrieved from http://www.escholarship.org/uc/item/5n3063xt

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

van der Poll, Thomas Scott. “Design, Synthesis and Theoretical Investigation of Small Molecules for Utility in Organic Semiconducting Devices.” 2014. Thesis, University of California – eScholarship, University of California. Accessed April 11, 2021. http://www.escholarship.org/uc/item/5n3063xt.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

van der Poll, Thomas Scott. “Design, Synthesis and Theoretical Investigation of Small Molecules for Utility in Organic Semiconducting Devices.” 2014. Web. 11 Apr 2021.

Vancouver:

van der Poll TS. Design, Synthesis and Theoretical Investigation of Small Molecules for Utility in Organic Semiconducting Devices. [Internet] [Thesis]. University of California – eScholarship, University of California; 2014. [cited 2021 Apr 11]. Available from: http://www.escholarship.org/uc/item/5n3063xt.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

van der Poll TS. Design, Synthesis and Theoretical Investigation of Small Molecules for Utility in Organic Semiconducting Devices. [Thesis]. University of California – eScholarship, University of California; 2014. Available from: http://www.escholarship.org/uc/item/5n3063xt

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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Open Access Theses and Dissertations