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Leiden University

1. Berman-de, Jong E.P. Viral infections in young infants: epidemiologic and diagnostic aspects of ToRCH, enterovirus and human parechovirus.

Degree: 2019, Leiden University

Congenital ‘ToRCH’ infections have a low incidence in The Netherlands but diagnostic testing occurs frequently for a variety of different indications, some of which aren’t necessary. On the contrary, EV- and HPeV infections have a high incidence infants, but are frequently missed due to lack of testing. Furthermore, knowledge about follow-up after a proven infection with EV or HPeV is scarce.The aim of the first part of this thesis (part A) was to investigate the yield of performing diagnostic tests for ‘ToRCH’ infections in newborn infants with lenticulostriate vasculopathy (LSV) or small for gestational age (SGA). In the second part of this thesis (part B) the epidemiology and follow-up of Entero- (EV) and Human Parechovirus (HPeV) induced sepsis-like illness in neonates and young infants was studied.This thesis updates and nuances the indications for testing for both groups of pathogens and provides insight in the follow-up after a proven infection with EV or HPeV. Advisors/Committee Members: Supervisor: Walther F.J., Lopriore E. Co-Supervisor: Brus F..

Subjects/Keywords: Young infants; Sepsis-like illness; ToRCH; Toxoplasmosis; Rubella; Cytomegalovirus; Herpes simplex virus; Enterovirus; Human Parechovirus; Diagnostic testing; Young infants; Sepsis-like illness; ToRCH; Toxoplasmosis; Rubella; Cytomegalovirus; Herpes simplex virus; Enterovirus; Human Parechovirus; Diagnostic testing

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Berman-de, J. E. P. (2019). Viral infections in young infants: epidemiologic and diagnostic aspects of ToRCH, enterovirus and human parechovirus. (Doctoral Dissertation). Leiden University. Retrieved from http://hdl.handle.net/1887/79982

Chicago Manual of Style (16th Edition):

Berman-de, Jong E P. “Viral infections in young infants: epidemiologic and diagnostic aspects of ToRCH, enterovirus and human parechovirus.” 2019. Doctoral Dissertation, Leiden University. Accessed September 24, 2020. http://hdl.handle.net/1887/79982.

MLA Handbook (7th Edition):

Berman-de, Jong E P. “Viral infections in young infants: epidemiologic and diagnostic aspects of ToRCH, enterovirus and human parechovirus.” 2019. Web. 24 Sep 2020.

Vancouver:

Berman-de JEP. Viral infections in young infants: epidemiologic and diagnostic aspects of ToRCH, enterovirus and human parechovirus. [Internet] [Doctoral dissertation]. Leiden University; 2019. [cited 2020 Sep 24]. Available from: http://hdl.handle.net/1887/79982.

Council of Science Editors:

Berman-de JEP. Viral infections in young infants: epidemiologic and diagnostic aspects of ToRCH, enterovirus and human parechovirus. [Doctoral Dissertation]. Leiden University; 2019. Available from: http://hdl.handle.net/1887/79982

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