subject:(Scientific Imaging)

Case Western Reserve University

1. Fennimore, Todd F. Understanding change in medicine and the biomedical sciences: Modeling change as interactions among flows with arrow diagrams.

Degree: MA, Cognitive Linguistics, 2011, Case Western Reserve University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=case1307626543

► Building on Aristotle’s analysis, this thesis starts with a definition of change as the result of a network of influences operating to shape a particular… (more)

Subjects/Keywords: Scientific Imaging; Systems Science; scientific reasoning; explanation; diagramming; cognitive science; modeling of change

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Fennimore, T. F. (2011). Understanding change in medicine and the biomedical sciences: Modeling change as interactions among flows with arrow diagrams. (Masters Thesis). Case Western Reserve University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=case1307626543

Chicago Manual of Style (16^th Edition):

Fennimore, Todd F. “Understanding change in medicine and the biomedical sciences: Modeling change as interactions among flows with arrow diagrams.” 2011. Masters Thesis, Case Western Reserve University. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1307626543.

MLA Handbook (7^th Edition):

Fennimore, Todd F. “Understanding change in medicine and the biomedical sciences: Modeling change as interactions among flows with arrow diagrams.” 2011. Web. 17 Aug 2019.

Vancouver:

Fennimore TF. Understanding change in medicine and the biomedical sciences: Modeling change as interactions among flows with arrow diagrams. [Internet] [Masters thesis]. Case Western Reserve University; 2011. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1307626543.

Council of Science Editors:

Fennimore TF. Understanding change in medicine and the biomedical sciences: Modeling change as interactions among flows with arrow diagrams. [Masters Thesis]. Case Western Reserve University; 2011. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1307626543

The Ohio State University

2. Wavreille, Vincent Alain. Correlation Between Histopathologic, Arthroscopic and Magnetic Resonance Imaging Findings in Dogs with Medial Coronoid Disease.

Degree: MS, Comparative and Veterinary Medicine, 2014, The Ohio State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1397060501

► Medial coronoid disease (MCD), a component of canine elbow dysplasia, is the most common cause of thoracic limb lameness in juvenile medium- to large-breed dogs.… (more)

▼ Medial coronoid disease (MCD), a component of canine elbow dysplasia, is the most common cause of thoracic limb lameness in juvenile medium- to large-breed dogs. The goal of this study is to describe the magnetic resonance imaging (MRI), arthroscopic and histopathological changes in dogs with medial coronoid disease and to identify potential relationships between these findings. Twenty-five diseased medial coronoid processes (MCP) were collected from 19 dogs with a confirmed diagnosis of medial coronoid disease that underwent surgical management with subtotal coronoid ostectomy. A reference group of normal MCPs was harvested from 9 dogs that were euthanatized for reasons unrelated to elbow disease. MCP specimens were evaluated by magnetic resonance imaging (MRI) using a novel grading scheme (all dogs), arthroscopy using a modified Outerbridge scheme (affected dogs only) and histopathology (all dogs). The common histopathologic findings were subchondral microfractures, subchondral microfractures continuous with cartilaginous fissures, moderate to severe hypercellularity of the marrow space, trabecular bone necrosis and articular cartilage degeneration. The severity of cartilage disease in the MCP was moderate to severe in most of the specimens, even in cases with minimal arthroscopic pathology. Three distinct patterns of bone marrow lesion (BML) were identified adjacent to the MCP, but there was no correlation between BML pattern and either histopathological or arthroscopic findings. There was moderate correlation between modified Outerbridge scores and MRI scores. No correlation was identified between the histopathological changes and either MRI or arthroscopic scores. There was no significant correlation between the clinical scores and histopathological changes. Ongoing improvements in the resolution of noninvasive imaging techniques will likely improve description and understanding of the MCP disease in dogs. Advisors/Committee Members: Allen, Matthew (Advisor).

Subjects/Keywords: Scientific Imaging; Veterinary Services; Surgery; Canine Elbow Dysplasia, MRI, Arthroscopy, Histopathology

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Wavreille, V. A. (2014). Correlation Between Histopathologic, Arthroscopic and Magnetic Resonance Imaging Findings in Dogs with Medial Coronoid Disease. (Masters Thesis). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1397060501

Chicago Manual of Style (16^th Edition):

Wavreille, Vincent Alain. “Correlation Between Histopathologic, Arthroscopic and Magnetic Resonance Imaging Findings in Dogs with Medial Coronoid Disease.” 2014. Masters Thesis, The Ohio State University. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1397060501.

MLA Handbook (7^th Edition):

Wavreille, Vincent Alain. “Correlation Between Histopathologic, Arthroscopic and Magnetic Resonance Imaging Findings in Dogs with Medial Coronoid Disease.” 2014. Web. 17 Aug 2019.

Vancouver:

Wavreille VA. Correlation Between Histopathologic, Arthroscopic and Magnetic Resonance Imaging Findings in Dogs with Medial Coronoid Disease. [Internet] [Masters thesis]. The Ohio State University; 2014. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1397060501.

Council of Science Editors:

Wavreille VA. Correlation Between Histopathologic, Arthroscopic and Magnetic Resonance Imaging Findings in Dogs with Medial Coronoid Disease. [Masters Thesis]. The Ohio State University; 2014. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1397060501

The Ohio State University

3. Hwangbo, Ju Won. Integration of Orbital and Ground Imagery for Automation of Rover Localization.

Degree: PhD, Geodetic Science and Surveying, 2010, The Ohio State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1276835399

► Rover localization is essential to the exploration of space. The availability of sub-meter resolution satellite imagery, especially High Resolution Imaging Science Experiment (HiRISE) onboard the… (more)

▼ Rover localization is essential to the exploration of space. The availability of sub-meter resolution satellite imagery, especially High Resolution Imaging Science Experiment (HiRISE) onboard the Mars Reconnaissance Orbiter (MRO), has opened the possibility of computing rover locations at higher accuracy by making use of detailed features seen in the satellite orbital images. This dissertation describes a new development towards automation of the rover localization process, using orbital and ground image networks.A HiRISE orbital image network on Mars is constructed based on a rigorous sensor model, bundle adjustment of HiRISE stereo images and absolute positioning using Mars Orbiter Laser Altimeter (MOLA) data. The unique HiRISE sensor configuration consists of 14 CCDs fixed to a focal plane. Due to the complexity of its sensor geometry, two technical issues need to be resolved in HiRISE stereo processing for precision topographic mapping. These technical issues are achieving coherence in the exterior orientation parameters between stereos as well as overlapping CCDs, and accurate geopositioning of HiRISE data without ground-control points. In this research, bundle adjustment strategies based on polynomial function models are applied to improve the exterior-orientation parameters. Disagreement between HiRISE CCDs is handled by the bundle adjustment, using inter-CCD tie points. HiRISE DTM was matched with MOLA DTM and points data to obtain the absolute position of the stereo model. Performance analysis of this new experiment will be given. A ground image network is also constructed using matching of Mars Exploration Rover (MER) stereo images. Rocks detected from both orbital and ground imagery serve as tie points for rover localization. From orbital images, rocks are extracted based on brightness values and the shape of dark spots. Rocks in ground images are extracted through dense stereo matching, rock peak and surface point extraction, and rock modeling. To narrow down a precise rover position, terrain matching is performed using DTMs generated from orbital and ground imagery. Finally, distribution pattern matching is implemented for rocks detected from orbital and ground imagery. The rover position is adjusted based on a 2-D affine transformation obtained from rock pattern matching. The proposed method has been tested for the Spirit rover traverse. Selection of optimal parameter values and quality control is discussed. Experimental results show that the orbital/ground rock matching approach has performed successfully for MER rover localization. Advisors/Committee Members: Saalfeld, Alan (Committee Chair), Li, Rongxing (Advisor).

Subjects/Keywords: Engineering; Robots; Scientific Imaging; Technology; Photogrammetry; image processing; rover localization

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hwangbo, J. W. (2010). Integration of Orbital and Ground Imagery for Automation of Rover Localization. (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1276835399

Chicago Manual of Style (16^th Edition):

Hwangbo, Ju Won. “Integration of Orbital and Ground Imagery for Automation of Rover Localization.” 2010. Doctoral Dissertation, The Ohio State University. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1276835399.

MLA Handbook (7^th Edition):

Hwangbo, Ju Won. “Integration of Orbital and Ground Imagery for Automation of Rover Localization.” 2010. Web. 17 Aug 2019.

Vancouver:

Hwangbo JW. Integration of Orbital and Ground Imagery for Automation of Rover Localization. [Internet] [Doctoral dissertation]. The Ohio State University; 2010. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1276835399.

Council of Science Editors:

Hwangbo JW. Integration of Orbital and Ground Imagery for Automation of Rover Localization. [Doctoral Dissertation]. The Ohio State University; 2010. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1276835399

The Ohio State University

4. Vogt, Keith M. Optimization of physiologic noise correction in functional magnetic resonance imaging.

Degree: PhD, Biomedical Engineering, 2009, The Ohio State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1243544877

► Though in widespread clinical and research use as a tool to evaluate brain function, functional magnetic resonance imaging (FMRI) data is severely contaminated by… (more)

▼ Though in widespread clinical and research use as a tool to evaluate brain function, functional magnetic resonance imaging (FMRI) data is severely contaminated by noise, due in large part to physiologic noise caused by respiratory and cardiac variations over time. This dissertation attempts to better characterize several physiologic noise correction techniques applied to pain FMRI data. Three studies are described that collectively work toward determining an optimal physiologic noise correction algorithm to be used in future pain FMRI studies. First, a novel algorithm, RetroSLICE, is described that uses linear regression to correct acquired images for signal intensity fluctuations correlated to measured respiratory, cardiac, and capnometry variations. The impact of this technique was assessed for a 1.5 T pain FMRI experiment. Each physiologic noise regressor used as a part of the RetroSLICE algorithm independently resulted in a decrease in timecourse variance and an improvement in model fit. Combined correction for the instantaneous effects of respiratory and cardiac variations caused a 5.4% decrease in signal variance and increased model fit (mean R²_a) by 65%. The addition of ETCO₂ correction as part of the general linear model led to 39% further improvement in model fit. Each of these corrections also caused changes in the group activation map. Next, an optimal transfer function between ETCO₂ level and BOLD signal changes was empirically determined using FMRI data in which paced breathing forced a 35% decrease in ETCO₂. ETCO₂ data convolved with this optimized response function was compared to another measure, the respiratory volume over time (RVT) convolved with an optimized respiration response function. When regressed against FMRI data collected during a breathing modulation task, ETCO₂ was more strongly and diffusely correlated to the data than RVT. Conversely, when the same comparative analysis was performed on pain FMRI data, RVT was more strongly correlated than ETCO₂. In both cases, allowing ± 2 s flexibility in the response function peak times did not change the relative correlation to the MR data of the ETCO₂ compared to the RVT timecourses. Finally, the well-known physiologic noise correction algorithm, RETROICOR, was implemented on pain FMRI data collected at 1.5 and 3.0 T. Respiratory and cardiac correction with Fourier series phase fitting caused an 8.2% decrease in signal variance and a 227% increase in model fit at 1.5 T, indicating performance superior to RetroSLICE. At 3.0 T, significantly greater improvements were seen: a 10.4% decrease in signal noise and 240% increase in mean R2a. ETCO₂ correction applied with the optimized response function previously determined caused insignificant changes in noise reduction and model fit. Further exploration of the properties of the RETROICOR algorithm showed no difference in impact when applied with physiologic input data… Advisors/Committee Members: Small, Robert (Committee Chair), Schmalbrock, Petra (Advisor).

Subjects/Keywords: Engineering; Radiology; Scientific Imaging; functional MRI; brain; pain; physiologic noise correction; RETROICOR; RetroSLICE; ETCO2

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Vogt, K. M. (2009). Optimization of physiologic noise correction in functional magnetic resonance imaging. (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1243544877

Chicago Manual of Style (16^th Edition):

Vogt, Keith M. “Optimization of physiologic noise correction in functional magnetic resonance imaging.” 2009. Doctoral Dissertation, The Ohio State University. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1243544877.

MLA Handbook (7^th Edition):

Vogt, Keith M. “Optimization of physiologic noise correction in functional magnetic resonance imaging.” 2009. Web. 17 Aug 2019.

Vancouver:

Vogt KM. Optimization of physiologic noise correction in functional magnetic resonance imaging. [Internet] [Doctoral dissertation]. The Ohio State University; 2009. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1243544877.

Council of Science Editors:

Vogt KM. Optimization of physiologic noise correction in functional magnetic resonance imaging. [Doctoral Dissertation]. The Ohio State University; 2009. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1243544877

Cornell University

5. Lieber, Danielle. Pyspectrum: An Open Source Software For Hyperspectral Analysis .

Degree: 2016, Cornell University

URL: http://hdl.handle.net/1813/45167

Subjects/Keywords: hyperspectral imaging; Raman spectroscopy; scientific programming

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lieber, D. (2016). Pyspectrum: An Open Source Software For Hyperspectral Analysis . (Thesis). Cornell University. Retrieved from http://hdl.handle.net/1813/45167

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Lieber, Danielle. “Pyspectrum: An Open Source Software For Hyperspectral Analysis .” 2016. Thesis, Cornell University. Accessed August 17, 2019. http://hdl.handle.net/1813/45167.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Lieber, Danielle. “Pyspectrum: An Open Source Software For Hyperspectral Analysis .” 2016. Web. 17 Aug 2019.

Vancouver:

Lieber D. Pyspectrum: An Open Source Software For Hyperspectral Analysis . [Internet] [Thesis]. Cornell University; 2016. [cited 2019 Aug 17]. Available from: http://hdl.handle.net/1813/45167.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Lieber D. Pyspectrum: An Open Source Software For Hyperspectral Analysis . [Thesis]. Cornell University; 2016. Available from: http://hdl.handle.net/1813/45167

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Case Western Reserve University

6. Wang, Fangjing. Biomedical Imaging of Stem Cells Using Reporter Genes.

Degree: PhD, Biomedical Engineering, 2010, Case Western Reserve University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=case1261441999

► Mesenchymal stem cells (MSCs), derived from nearly all adult organs, can differentiate into multiple lineages including osteoblasts, chondrocytes and adipocytes under different local micro-environments… (more)

▼ Mesenchymal stem cells (MSCs), derived from nearly all adult organs, can differentiate into multiple lineages including osteoblasts, chondrocytes and adipocytes under different local micro-environments for tissue repair. MSCs have also shown to ameliorate graft versus host disease (GVHD) caused by allogeneic hematopoietic stem cell transplantation, via suppressing the activation and proliferation of the alloreactive lymphocytes. Therefore, MSCs have great potential in bone tissue regeneration and stem cell-based therapies. However, previous techniques to track stem cells in vivo are usually associated with frequent animal sacrifice followed by subsequent histology analysis or RT-PCR verification. A continuous, non-invasive, real time and longitudinal imaging technique is lacking. In this study, we aimed to establish such a platform technology to image stem cell biodistribution in a disease model (GVHD) in vivo. A triple-reporter gene containing luc-mrfp–ttk was incorporated into hMSCs via lentiviral transduction. The gene of luc was imaged with BLI and ttk imaged with PET. The proliferation rate of the transduced stem cells was reduced compared to the wild type cells although the stem cell differentiation potential was reserved. The transcriptional changes between transduced and wild-type stem cells were examined via gene microarrays to identify the key genes related to proliferation and mesenchymal differentiation to determine the transduction effect. Stem cells that were loaded into ceramic cubes and implanted into NOD/SCID mice s.c. were longitudinally imaged in vivo by BLI for more than 3 months. PET was also capable of imaging the implanted stem cells in the ceramic cubes. Histology studies confirmed the formation of bone from the transduced hMSCs in vivo. These indicate that the imaging template was successfully developed. In an animal model of GVHD developed in mice, hMSCs were injected intravenously for the treatment of this disease. It was shown that hMSCs enhanced the survival of the GVHD mice compared to the untreated mice. BLI results showed primary entrapment of hMSCs in lung, while only a small fraction of cells transiently migrated to the intestine. Cells in the mice were undetectable 7 days after their transplantation. Although arterial injection led to enhanced cell distribution into different organs such as intestines, and prolonged hMSC retention in allogeneic mice, no efficacy was observed compared with the control group possibly due to the injury associated with the surgery procedure that allowed arterial injection. These data suggest that timely cell injection and repeated injection may be necessary to effectively prevent or alleviate this disease. In summary, this imaging technology plays an important role in tracking stem cells, in revealing disease development mechanisms, as well as in optimizing stem cell treatment strategy. Advisors/Committee Members: Saidel, Gerald (Committee Chair), Lee, Zhenghong (Advisor).

Subjects/Keywords: Biomedical Research; Engineering; Scientific Imaging; Imaging; BLI; PET; GVHD; mesenchymal stem cells; reporter gene; non-invasive; repeated

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Wang, F. (2010). Biomedical Imaging of Stem Cells Using Reporter Genes. (Doctoral Dissertation). Case Western Reserve University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=case1261441999

Chicago Manual of Style (16^th Edition):

Wang, Fangjing. “Biomedical Imaging of Stem Cells Using Reporter Genes.” 2010. Doctoral Dissertation, Case Western Reserve University. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1261441999.

MLA Handbook (7^th Edition):

Wang, Fangjing. “Biomedical Imaging of Stem Cells Using Reporter Genes.” 2010. Web. 17 Aug 2019.

Vancouver:

Wang F. Biomedical Imaging of Stem Cells Using Reporter Genes. [Internet] [Doctoral dissertation]. Case Western Reserve University; 2010. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1261441999.

Council of Science Editors:

Wang F. Biomedical Imaging of Stem Cells Using Reporter Genes. [Doctoral Dissertation]. Case Western Reserve University; 2010. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1261441999

Case Western Reserve University

7. Fleming, Christine P. Characterization of Cardiac Tissue Using Optical Coherence Tomography.

Degree: PhD, Biomedical Engineering, 2010, Case Western Reserve University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=case1270718628

► Radiofrequency ablation (RFA) therapy is the standard of care for the treatment of cardiac arrhythmias. Current techniques to guide ablation therapy utilize low resolution two… (more)

▼ Radiofrequency ablation (RFA) therapy is the standard of care for the treatment of cardiac arrhythmias. Current techniques to guide ablation therapy utilize low resolution two dimensional fluoroscopic images and functional measurements from the RFA catheter, temperature, impedance and electrograms. High resolution, depth resolved imaging is needed to characterize early structural changes in the myocardium due to disease and therapy. Optical coherence tomography (OCT) is a noninvasive imaging modality that provides high resolution, depth resolved imaging of tissue microstructure in real time. OCT provides subsurface imaging of depths 1-2 mm in cardiac tissue with high spatial resolution (~10 µm) in three dimensions and high sensitivity in vivo. An automated algorithm for fiber orientation quantification in the plane parallel to the wall surface was developed. The algorithm was applied to volumetric image sets of wild type mouse ventricles, and normal and infarctions within rabbit ventricles. Using an ex vivo wedge swine model, we demonstrated that OCT can distinguish necrotic ablation lesions from untreated tissue and identify precursors to overtreatment. OCT image features were observed that clearly distinguish untreated myocardium, ablation lesions, epicardial fat, and coronary vessels and assess tissue contact with catheter based imaging, potential critical structures for real-time guidance of epicardial RFA therapy. A forward scanning OCT catheter was prototyped that provides contact, cone scanning with no metal was used to visualization of real time increase in intensity and decrease in gradient strength and imaging ex vivo of the endocardial surface of the right ventricle submerged in heparinized blood, where an image of the myocardium was obtained when the catheter was in direct contact with the tissue, displacing the blood. Using the forward imaging probe, we demonstrated the first use of OCT to image the endocaridum and visualize dynamics due to RF energy delivery in a living animal. OCT can provide real-time direct visualization of RFA treatment to confirm energy delivery and visualize lesion formation, image in the presence of blood, visualize critical structures and potentially identify arrhythmogenic substrates. This feedback may increase RFA therapy procedural success, reduce procedural time, and reduce complication rates. Advisors/Committee Members: Rollins, Andrew (Advisor).

Subjects/Keywords: Biomedical Research; Engineering; Optics; Scientific Imaging; optical coherence tomography; biomedical optics; image processing; cardiac imaging; radiofrequency ablation

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Fleming, C. P. (2010). Characterization of Cardiac Tissue Using Optical Coherence Tomography. (Doctoral Dissertation). Case Western Reserve University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=case1270718628

Chicago Manual of Style (16^th Edition):

Fleming, Christine P. “Characterization of Cardiac Tissue Using Optical Coherence Tomography.” 2010. Doctoral Dissertation, Case Western Reserve University. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1270718628.

MLA Handbook (7^th Edition):

Fleming, Christine P. “Characterization of Cardiac Tissue Using Optical Coherence Tomography.” 2010. Web. 17 Aug 2019.

Vancouver:

Fleming CP. Characterization of Cardiac Tissue Using Optical Coherence Tomography. [Internet] [Doctoral dissertation]. Case Western Reserve University; 2010. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1270718628.

Council of Science Editors:

Fleming CP. Characterization of Cardiac Tissue Using Optical Coherence Tomography. [Doctoral Dissertation]. Case Western Reserve University; 2010. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1270718628

Case Western Reserve University

8. Young, Elizabeth Ann. Axonal Na/K ATPase: Localization, Loss, and Lessons Learned.

Degree: PhD, Neurosciences, 2010, Case Western Reserve University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=case1278699912

► Degeneration of chronically demyelinated axons is the leading causative factor in the progression of symptoms experienced by patients with multiple sclerosis (MS), despite the fact… (more)

▼ Degeneration of chronically demyelinated axons is the leading causative factor in the progression of symptoms experienced by patients with multiple sclerosis (MS), despite the fact that MS has defied classification as a primary neurodegenerative disease. While there are many potential causes of neuronal damage immediately following demyelination, it is within the context of chronic demyelination that the fundamental and intrinsic mechanisms of axonal function can, themselves, become detrimental to axonal integrity. In the wake of demyelination, extensive submembranous cytoskeletal derangement occurs, allowing the once-nodal voltage-gated sodium channels (NaV) to diffuse along the denuded length of the axon. The immediate impact on the axon is two-fold; first is a spatially unrestricted influx of sodium and an associated increase in axoplasmic sodium ([Na]i), second is abrogation of saltatory conduction, which relies on focal sodium influx. In response to a global increase in [Na]i, typically caused by an action potential, the sodium/potassium adenosine triphosphatase (Na/K ATPase), or the sodium pump, hydrolyzes ATP to power the active transport of three intracellular sodium ions for two extracellular potassium ions and, thereby, repolarization of the cell. The cell is driven into an energy debt, causing stress to mitochondria and, thereby, decreasingATP production. Without sufficient axonal ATP, the Na/K ATPase cannot transport ions across the axolemma. With the Na/K ATPases unable to transport additional sodium across the axolemma, [Na]i increases and the sodium/calcium exchanger (NCX) is driven to reverse its function and exchange intracellular sodium for extracellular calcium. An unchecked rise in axoplasmic calcium can lead to the induction of many deleterious calcium-dependent degradative pathways and the eventual degeneration of the demyelinated axon. In these studies, the “secondary neurodegeneration” of MS is explored; specifically, how the energetic properties of the chronically demyelinated axon lead to a series of events, beginning, most notably, with the loss of the Na/K ATPase, that lead to a run-down of the axolemmal membrane potential and, eventually, axonal degeneration. Advisors/Committee Members: Miller, Robert (Committee Chair), Trapp, Bruce (Advisor).

Subjects/Keywords: Anatomy and Physiology; Biology; Biomedical Research; Neurology; Pharmaceuticals; Scientific Imaging; Axonal Degeneration; Neurodegeneration; multiple sclerosis; MRI; MTR; T1; imaging

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Young, E. A. (2010). Axonal Na/K ATPase: Localization, Loss, and Lessons Learned. (Doctoral Dissertation). Case Western Reserve University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=case1278699912

Chicago Manual of Style (16^th Edition):

Young, Elizabeth Ann. “Axonal Na/K ATPase: Localization, Loss, and Lessons Learned.” 2010. Doctoral Dissertation, Case Western Reserve University. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1278699912.

MLA Handbook (7^th Edition):

Young, Elizabeth Ann. “Axonal Na/K ATPase: Localization, Loss, and Lessons Learned.” 2010. Web. 17 Aug 2019.

Vancouver:

Young EA. Axonal Na/K ATPase: Localization, Loss, and Lessons Learned. [Internet] [Doctoral dissertation]. Case Western Reserve University; 2010. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1278699912.

Council of Science Editors:

Young EA. Axonal Na/K ATPase: Localization, Loss, and Lessons Learned. [Doctoral Dissertation]. Case Western Reserve University; 2010. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1278699912

Miami University

9. Taulbee, Anita R. Terahertz Time-Domain Spectroscopy and Imaging of Biological Compounds and Tissues.

Degree: PhD, Chemistry, 2009, Miami University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=miami1249412289

► This dissertation consists of four chapters detailing terahertz time-domain spectroscopy (THz-TDS) and the application thereof to the investigation of biological samples and related analytes.… (more)

▼ This dissertation consists of four chapters detailing terahertz time-domain spectroscopy (THz-TDS) and the application thereof to the investigation of biological samples and related analytes. Chapter 1 provides a background of the evolution of THz-TDS from a historical and physics/engineering perspective followed by an extensive section from a chemistry perspective dedicated to the interaction of THz radiation with matter. A variety of measurement techniques are discussed, culminating in a literature review. Chapter 2 focuses on the investigation of the 20 essential amino acids as crystalline solids using THz spectroscopy, in which absorbance of THz frequencies by crystal lattice phonon propagation is documented. A study dedicated to qualitative analysis of L-alanine introduces a novel approach for the spectral assignment of the observed THz absorbance frequencies to the crystal structure of the analyte. Chapter 3 presents the study of five types of excised human breast tissue – normal, benign, lobular carcinoma, ductal carcinoma in situ and invasive ductal carcinoma – using THz pulsed imaging, which consists of successive THz-TDS measurements over a two-dimensional space. The presentation and evaluation of the tissue images are supplemented with the examination of frequency-domain reflectance spectra of selected tissue areas. The results of the studies presented herein are followed by detailed guidelines for the maximization of the efficiency and benefit of continued pursuits in this field. Chapter 4 investigates the potential of reflectance-mode THz-TDS as a method for the non-destructive determination of the gel-point of sol-gel monoliths. Results are used to compare the gel point properties of sol-gels with and without a stabilizing dendrimer. The conclusions are found to support a particular theory concerning the stabilization mechanism of the dendrimer in the sol-gel process. Advisors/Committee Members: Cox, James (Committee Chair), Pacey, Gilbert (Advisor).

Subjects/Keywords: Analytical Chemistry; Biomedical Research; Chemistry; Experiments; Molecules; Radiation; Scientific Imaging; Statistics; terahertz; spectroscopy; imaging; cancer; amino acid; L-alanine; statistics

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Taulbee, A. R. (2009). Terahertz Time-Domain Spectroscopy and Imaging of Biological Compounds and Tissues. (Doctoral Dissertation). Miami University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=miami1249412289

Chicago Manual of Style (16^th Edition):

Taulbee, Anita R. “Terahertz Time-Domain Spectroscopy and Imaging of Biological Compounds and Tissues.” 2009. Doctoral Dissertation, Miami University. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=miami1249412289.

MLA Handbook (7^th Edition):

Taulbee, Anita R. “Terahertz Time-Domain Spectroscopy and Imaging of Biological Compounds and Tissues.” 2009. Web. 17 Aug 2019.

Vancouver:

Taulbee AR. Terahertz Time-Domain Spectroscopy and Imaging of Biological Compounds and Tissues. [Internet] [Doctoral dissertation]. Miami University; 2009. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=miami1249412289.

Council of Science Editors:

Taulbee AR. Terahertz Time-Domain Spectroscopy and Imaging of Biological Compounds and Tissues. [Doctoral Dissertation]. Miami University; 2009. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=miami1249412289

Florida International University

10. Villacob, Raul A. Development of a Primary Ion Column for Mass Spectrometry-Based Surface Analysis.

Degree: MS, Chemistry, 2016, Florida International University

URL: http://digitalcommons.fiu.edu/etd/2561 ; 10.25148/etd.FIDC000761 ; FIDC000761

► Secondary Ion Mass Spectrometry (SIMS) is a powerful technique for high spatial resolution chemical mapping and characterization of native surfaces. The use of massive… (more)

Subjects/Keywords: Mass Spectrometry; Analytical Chemistry; Scientific Instrumentation Development; Focused Ion Beams; Surface Analysis; Mass Spectrometry Imaging; Nanoscale Imaging; Analytical Chemistry

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Villacob, R. A. (2016). Development of a Primary Ion Column for Mass Spectrometry-Based Surface Analysis. (Thesis). Florida International University. Retrieved from http://digitalcommons.fiu.edu/etd/2561 ; 10.25148/etd.FIDC000761 ; FIDC000761

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Villacob, Raul A. “Development of a Primary Ion Column for Mass Spectrometry-Based Surface Analysis.” 2016. Thesis, Florida International University. Accessed August 17, 2019. http://digitalcommons.fiu.edu/etd/2561 ; 10.25148/etd.FIDC000761 ; FIDC000761.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Villacob, Raul A. “Development of a Primary Ion Column for Mass Spectrometry-Based Surface Analysis.” 2016. Web. 17 Aug 2019.

Vancouver:

Villacob RA. Development of a Primary Ion Column for Mass Spectrometry-Based Surface Analysis. [Internet] [Thesis]. Florida International University; 2016. [cited 2019 Aug 17]. Available from: http://digitalcommons.fiu.edu/etd/2561 ; 10.25148/etd.FIDC000761 ; FIDC000761.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Villacob RA. Development of a Primary Ion Column for Mass Spectrometry-Based Surface Analysis. [Thesis]. Florida International University; 2016. Available from: http://digitalcommons.fiu.edu/etd/2561 ; 10.25148/etd.FIDC000761 ; FIDC000761

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Akron

11. Narayan, Chaya. Polarimetric Stokes Imaging for the Detection of Tumor Margins and Segmentation.

Degree: MSin Engineering, Electrical Engineering, 2013, University of Akron

URL: http://rave.ohiolink.edu/etdc/view?acc_num=akron1386785379

► Cancer is the second most common cause of death in the US and is responsible for about 25% of the deaths according to the American… (more)

▼ Cancer is the second most common cause of death in the US and is responsible for about 25% of the deaths according to the American Cancer Society. There is a need for quick and accurate detection of tumors in a real time automated environment without the delays associated with laboratory procedures. There is also a need to identify the exact location and extent of the tumor tissues so that surgeries would not only be more effective but also as minimally invasive as possible. The purpose of this study was to distinguish the margins between healthy and cancerous tissues on slides containing samples of mice brain tumor through the use of polarimetric stokes imaging techniques. Comparison between the cancerous and healthy tissue portions from polarimetric imaging was expected to provide better distinction of the two areas and the margin between them.The experiments were conducted with a broadband white light source and the data was recorded using a circular polarized rotating retarder system in transmission mode. The samples used were unstained sliced sections of mice brain prepared using standard procedures. The images were saved with an optical camera that was impartial to color or fluorescence properties of the samples. The Stokes parameter images of the samples were computed through the Fourier analysis method. The images for Degree of Polarization (DOP), Degree of Linear Polarization (DOLP) and Degree of Circular Polarization (DOCP) were also computed. The images thus generated were segmented and post-processed to analyze properties such as texture and tissue density. Additionally, small selections of tumor and healthy tissue having the same pixel area were chosen from the Stokes images for further statistical analyses.The statistical findings from this study showed that image features of tumor tissue had lower variance values to the various degrees of polarization when compared to that of normal tissue. This meant that the surface of tumors were more densely packed and more uniform than healthy tissue thus enabling successful segmentation, thereby proving the expectation that polarimetric stokes imaging was an efficient and robust tool in the detection of margins. Advisors/Committee Members: Giakos, George C. (Advisor).

Subjects/Keywords: Biology; Biomedical Engineering; Biomedical Research; Electrical Engineering; Engineering; Experiments; Health; Health Care; Health Sciences; Optics; Pathology; Scientific Imaging; Technology; Polarimetry, Stokes Imaging, Cancer margins, Segmentation, Polarimetric Imaging

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Narayan, C. (2013). Polarimetric Stokes Imaging for the Detection of Tumor Margins and Segmentation. (Masters Thesis). University of Akron. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=akron1386785379

Chicago Manual of Style (16^th Edition):

Narayan, Chaya. “Polarimetric Stokes Imaging for the Detection of Tumor Margins and Segmentation.” 2013. Masters Thesis, University of Akron. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=akron1386785379.

MLA Handbook (7^th Edition):

Narayan, Chaya. “Polarimetric Stokes Imaging for the Detection of Tumor Margins and Segmentation.” 2013. Web. 17 Aug 2019.

Vancouver:

Narayan C. Polarimetric Stokes Imaging for the Detection of Tumor Margins and Segmentation. [Internet] [Masters thesis]. University of Akron; 2013. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=akron1386785379.

Council of Science Editors:

Narayan C. Polarimetric Stokes Imaging for the Detection of Tumor Margins and Segmentation. [Masters Thesis]. University of Akron; 2013. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=akron1386785379

University of Akron

12. Ravi, Anandh. Efficacy of a Multi-Channel Array Coil for Pediatric Cardiac Magnetic Resonance Imaging.

Degree: MSin Engineering, Biomedical Engineering, 2008, University of Akron

URL: http://rave.ohiolink.edu/etdc/view?acc_num=akron1226615129

► Pediatric MR imaging currently uses adult RF coils which reduces the quality of pediatric images considering the large field of view and low signal to… (more)

Subjects/Keywords: Biomedical Research; Engineering; Health Care; Radiology; Scientific Imaging; RF coil; MRI; Cardiac; Infant cardiac imaging; Radiology; Magnetic Resonance Imaging; Infant cadiac array

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ravi, A. (2008). Efficacy of a Multi-Channel Array Coil for Pediatric Cardiac Magnetic Resonance Imaging. (Masters Thesis). University of Akron. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=akron1226615129

Chicago Manual of Style (16^th Edition):

Ravi, Anandh. “Efficacy of a Multi-Channel Array Coil for Pediatric Cardiac Magnetic Resonance Imaging.” 2008. Masters Thesis, University of Akron. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=akron1226615129.

MLA Handbook (7^th Edition):

Ravi, Anandh. “Efficacy of a Multi-Channel Array Coil for Pediatric Cardiac Magnetic Resonance Imaging.” 2008. Web. 17 Aug 2019.

Vancouver:

Ravi A. Efficacy of a Multi-Channel Array Coil for Pediatric Cardiac Magnetic Resonance Imaging. [Internet] [Masters thesis]. University of Akron; 2008. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=akron1226615129.

Council of Science Editors:

Ravi A. Efficacy of a Multi-Channel Array Coil for Pediatric Cardiac Magnetic Resonance Imaging. [Masters Thesis]. University of Akron; 2008. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=akron1226615129

Case Western Reserve University

13. Heise, Erich A. Development and Commercialization of Functional, Non-Invasive Retinal Imaging Device Utilizing Quantification of Flavoprotein Fluorescence for the Diagnosis and Monitoring of Retinal Disease.

Degree: MSs, Biology, 2016, Case Western Reserve University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=case1458921113

► Diabetes and its related complications are becoming increasingly more prevalent in the United States and other developed countries. Additionally, an increasingly earlier age of onset… (more)

Subjects/Keywords: Scientific Imaging; Biochemistry; Biology; Biomedical Engineering; Biophysics; Cellular Biology; Entrepreneurship; Health; Medical Imaging; Ophthalmology; flavoprotein fluorescence; retinal metabolic analysis; OcuSciences; functional retinal imager; biotechnology; retinal imaging; FPF

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Heise, E. A. (2016). Development and Commercialization of Functional, Non-Invasive Retinal Imaging Device Utilizing Quantification of Flavoprotein Fluorescence for the Diagnosis and Monitoring of Retinal Disease. (Masters Thesis). Case Western Reserve University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=case1458921113

Chicago Manual of Style (16^th Edition):

Heise, Erich A. “Development and Commercialization of Functional, Non-Invasive Retinal Imaging Device Utilizing Quantification of Flavoprotein Fluorescence for the Diagnosis and Monitoring of Retinal Disease.” 2016. Masters Thesis, Case Western Reserve University. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1458921113.

MLA Handbook (7^th Edition):

Heise, Erich A. “Development and Commercialization of Functional, Non-Invasive Retinal Imaging Device Utilizing Quantification of Flavoprotein Fluorescence for the Diagnosis and Monitoring of Retinal Disease.” 2016. Web. 17 Aug 2019.

Vancouver:

Heise EA. Development and Commercialization of Functional, Non-Invasive Retinal Imaging Device Utilizing Quantification of Flavoprotein Fluorescence for the Diagnosis and Monitoring of Retinal Disease. [Internet] [Masters thesis]. Case Western Reserve University; 2016. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1458921113.

Council of Science Editors:

Heise EA. Development and Commercialization of Functional, Non-Invasive Retinal Imaging Device Utilizing Quantification of Flavoprotein Fluorescence for the Diagnosis and Monitoring of Retinal Disease. [Masters Thesis]. Case Western Reserve University; 2016. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1458921113

Cleveland State University

14. Ergin, Leanna N. ENHANCED DATA REDUCTION, SEGMENTATION, AND SPATIAL MULTIPLEXING METHODS FOR HYPERSPECTRAL IMAGING.

Degree: PhD, College of Sciences and Health Professions, 2017, Cleveland State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=csu1501871494997272

► A hyperspectral image is a dataset consisting of both spectra and spatial information. It can be thought of either as a full spectrum taken at… (more)

▼ A hyperspectral image is a dataset consisting of both spectra and spatial information. It can be thought of either as a full spectrum taken at many pixel locations on a sample or many images of the same sample, each at a different wavelength. In recent decades, hyperspectral imaging has become a routine analytical method due to rapid advances in instrumentation and technique. Advances such as the speed of data acquisition, improved signal-to-noise-ratio, improved spatial resolution, and miniaturization of the instrumentation have all occurred, making chemical imaging methods more robust and more widely used. The work presented here deals with three issues in the field of hyperspectral imaging: unassisted data processing that is chemically meaningful and allows for subsequent chemometric analyses, visualization of the data that utilizes the full colorspace of modern red, green, blue (RGB) displays, and data collection with improved signal-to-noise ratios and comparably short acquisition times. Hyperspectral image data processing is a fundamental challenge in the field. There is a need for reliable processing techniques that can operate on the large amount of data in a hyperspectral image dataset. Because of the large quantity of data, currently-used methods for data processing are problematic because of how time-consuming and calculation-intensive they are or because of increased error that is observed in the less-intensive methods. The work presented here includes a user-unassisted method for rapidly generating chemical-based image contrast from hyperspectral image data. Our method, reduction of spectral images (ROSI), is an effective hyperspectral image processing method. A full theoretical description of the method is given along with performance metrics. The description has been generalized to work with any number of wavelength dimensions and spectra. A concise protocol is put forth that will enable other researchers to utilize this method by following a short, simple list of steps. ROSI can also be used as a data reduction method, as it achieves a threshold information density in the spectral dimension for all image pixels. ROSI results are suitable for subsequent data analysis enabling ROSI to be performed alone or as a preprocessing data reduction step. This research also improves upon a spatially-multiplexed Raman imaging system based on the digital micromirror device (DMD). The system provides signal-to-noise ratio enhancement while maintaining laser powers below the damage threshold of the sample and comparably short acquisition times. In the work presented here, the spatial resolution of the DMD imager has been improved such that features with a width of 2.19µm could be resolved, whereas the previous limit was 7.81µm. Advisors/Committee Members: Turner, John (Advisor).

Subjects/Keywords: Chemistry; Analytical Chemistry; Scientific Imaging; hyperspectral imaging; chemical imaging; data reduction; image segmentation; direction cosine; principal component analysis; PCA; reduction of spectral angle; ROSI; digital micromirror device; spatial multiplexing

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ergin, L. N. (2017). ENHANCED DATA REDUCTION, SEGMENTATION, AND SPATIAL MULTIPLEXING METHODS FOR HYPERSPECTRAL IMAGING. (Doctoral Dissertation). Cleveland State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=csu1501871494997272

Chicago Manual of Style (16^th Edition):

Ergin, Leanna N. “ENHANCED DATA REDUCTION, SEGMENTATION, AND SPATIAL MULTIPLEXING METHODS FOR HYPERSPECTRAL IMAGING.” 2017. Doctoral Dissertation, Cleveland State University. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=csu1501871494997272.

MLA Handbook (7^th Edition):

Ergin, Leanna N. “ENHANCED DATA REDUCTION, SEGMENTATION, AND SPATIAL MULTIPLEXING METHODS FOR HYPERSPECTRAL IMAGING.” 2017. Web. 17 Aug 2019.

Vancouver:

Ergin LN. ENHANCED DATA REDUCTION, SEGMENTATION, AND SPATIAL MULTIPLEXING METHODS FOR HYPERSPECTRAL IMAGING. [Internet] [Doctoral dissertation]. Cleveland State University; 2017. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=csu1501871494997272.

Council of Science Editors:

Ergin LN. ENHANCED DATA REDUCTION, SEGMENTATION, AND SPATIAL MULTIPLEXING METHODS FOR HYPERSPECTRAL IMAGING. [Doctoral Dissertation]. Cleveland State University; 2017. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=csu1501871494997272

McMaster University

15. Moghadas, Maryam. Type-Safety for Inverse Imaging Problems.

Degree: MSc, 2012, McMaster University

URL: http://hdl.handle.net/11375/12487

►

This thesis gives a partial answer to the question: “Can type systems detect modeling errors in scientific computing, particularly for inverse problems derived from… (more)

Subjects/Keywords: type-safety; Inverse Imaging Problem; Type Level Programming; Haskell; Regularization; formalization; Numerical Analysis and Scientific Computing; Programming Languages and Compilers; Numerical Analysis and Scientific Computing

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Moghadas, M. (2012). Type-Safety for Inverse Imaging Problems. (Masters Thesis). McMaster University. Retrieved from http://hdl.handle.net/11375/12487

Chicago Manual of Style (16^th Edition):

Moghadas, Maryam. “Type-Safety for Inverse Imaging Problems.” 2012. Masters Thesis, McMaster University. Accessed August 17, 2019. http://hdl.handle.net/11375/12487.

MLA Handbook (7^th Edition):

Moghadas, Maryam. “Type-Safety for Inverse Imaging Problems.” 2012. Web. 17 Aug 2019.

Vancouver:

Moghadas M. Type-Safety for Inverse Imaging Problems. [Internet] [Masters thesis]. McMaster University; 2012. [cited 2019 Aug 17]. Available from: http://hdl.handle.net/11375/12487.

Council of Science Editors:

Moghadas M. Type-Safety for Inverse Imaging Problems. [Masters Thesis]. McMaster University; 2012. Available from: http://hdl.handle.net/11375/12487

Wright State University

16. Schrider, Christina Da-Wann. Histogram-based template matching object detection in images with varying brightness and contrast.

Degree: MSEgr, Biomedical Engineering, 2008, Wright State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=wright1224044521

► Our challenge was to develop a semi-automatic target detection algorithm to aid human operators in locating potential targets within images. In contrast to currently available… (more)

Subjects/Keywords: Biomedical Research; Engineering; Scientific Imaging; object detection; target detection; computer-aided diagnosis; template matching; image contrast

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Schrider, C. D. (2008). Histogram-based template matching object detection in images with varying brightness and contrast. (Masters Thesis). Wright State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=wright1224044521

Chicago Manual of Style (16^th Edition):

Schrider, Christina Da-Wann. “Histogram-based template matching object detection in images with varying brightness and contrast.” 2008. Masters Thesis, Wright State University. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=wright1224044521.

MLA Handbook (7^th Edition):

Schrider, Christina Da-Wann. “Histogram-based template matching object detection in images with varying brightness and contrast.” 2008. Web. 17 Aug 2019.

Vancouver:

Schrider CD. Histogram-based template matching object detection in images with varying brightness and contrast. [Internet] [Masters thesis]. Wright State University; 2008. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=wright1224044521.

Council of Science Editors:

Schrider CD. Histogram-based template matching object detection in images with varying brightness and contrast. [Masters Thesis]. Wright State University; 2008. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=wright1224044521

University of Cincinnati

17. DICK, ERIC TIMOTHY. A Survey of CT Phantom Considerations for the Study of Blooming Artifacts as Observed in CT Coronary Angiography Studies: A Preliminary Study.

Degree: MS, Medicine : Radiology-Radiological Sciences (Medical Physics), 2008, University of Cincinnati

URL: http://rave.ohiolink.edu/etdc/view?acc_num=ucin1205313085

► The presence of image "blooming" artifacts, in particular with respect to highly calcifiedplaques, has been a major impediment to the implementation of Multi-detectorComputed Tomography (MD-CT)… (more)

Subjects/Keywords: Radiation; Radiology; Scientific Imaging; blooming; computed tomography; artifact; CT; beam hardening; partial volume averaging; cone beam

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

DICK, E. T. (2008). A Survey of CT Phantom Considerations for the Study of Blooming Artifacts as Observed in CT Coronary Angiography Studies: A Preliminary Study. (Masters Thesis). University of Cincinnati. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=ucin1205313085

Chicago Manual of Style (16^th Edition):

DICK, ERIC TIMOTHY. “A Survey of CT Phantom Considerations for the Study of Blooming Artifacts as Observed in CT Coronary Angiography Studies: A Preliminary Study.” 2008. Masters Thesis, University of Cincinnati. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1205313085.

MLA Handbook (7^th Edition):

DICK, ERIC TIMOTHY. “A Survey of CT Phantom Considerations for the Study of Blooming Artifacts as Observed in CT Coronary Angiography Studies: A Preliminary Study.” 2008. Web. 17 Aug 2019.

Vancouver:

DICK ET. A Survey of CT Phantom Considerations for the Study of Blooming Artifacts as Observed in CT Coronary Angiography Studies: A Preliminary Study. [Internet] [Masters thesis]. University of Cincinnati; 2008. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=ucin1205313085.

Council of Science Editors:

DICK ET. A Survey of CT Phantom Considerations for the Study of Blooming Artifacts as Observed in CT Coronary Angiography Studies: A Preliminary Study. [Masters Thesis]. University of Cincinnati; 2008. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=ucin1205313085

Case Western Reserve University

18. Mamolen, Megan Christine. DROSOPHILA MELANOGASTER DIS3 IS A DYNAMIC ENDO- AND 3’ to 5’ EXORIBONUCLEASE.

Degree: PhD, Molecular Biology and Microbiology, 2010, Case Western Reserve University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=case1278525341

► Dis3 is an evolutionarily conserved and essential enzyme with functions in mitosis, and RNA processing and turnover. In this work, we employed both in vitro… (more)

Subjects/Keywords: Biochemistry; Biology; Cellular Biology; Experiments; Molecular Biology; Scientific Imaging; Dis3; exosome; endoribonuclease; exoribonuclease; mitochondria; RNA turnover

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Mamolen, M. C. (2010). DROSOPHILA MELANOGASTER DIS3 IS A DYNAMIC ENDO- AND 3’ to 5’ EXORIBONUCLEASE. (Doctoral Dissertation). Case Western Reserve University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=case1278525341

Chicago Manual of Style (16^th Edition):

Mamolen, Megan Christine. “DROSOPHILA MELANOGASTER DIS3 IS A DYNAMIC ENDO- AND 3’ to 5’ EXORIBONUCLEASE.” 2010. Doctoral Dissertation, Case Western Reserve University. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1278525341.

MLA Handbook (7^th Edition):

Mamolen, Megan Christine. “DROSOPHILA MELANOGASTER DIS3 IS A DYNAMIC ENDO- AND 3’ to 5’ EXORIBONUCLEASE.” 2010. Web. 17 Aug 2019.

Vancouver:

Mamolen MC. DROSOPHILA MELANOGASTER DIS3 IS A DYNAMIC ENDO- AND 3’ to 5’ EXORIBONUCLEASE. [Internet] [Doctoral dissertation]. Case Western Reserve University; 2010. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1278525341.

Council of Science Editors:

Mamolen MC. DROSOPHILA MELANOGASTER DIS3 IS A DYNAMIC ENDO- AND 3’ to 5’ EXORIBONUCLEASE. [Doctoral Dissertation]. Case Western Reserve University; 2010. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1278525341

University of Toledo Health Science Campus

19. Zahedi, Shadi. Are Mitochondria a Potential Target for Anti-Cancer Therapy in Carcinoid Tumors?.

Degree: MSBS, College of Medicine, 2010, University of Toledo Health Science Campus

URL: http://rave.ohiolink.edu/etdc/view?acc_num=mco1280427079

► Gastrointestinal (GI) carcinoids are slow growing malignancies of neuroendocrine phenotype that can behave aggressively. To date, there are no effective therapies for metastatic carcinoid cancer.… (more)

Subjects/Keywords: Biomedical Research; Molecular Biology; Scientific Imaging; carcinoid tumors; mitochondrial; calcium signaling; TIRF microscopy; oxidant therapy; vitamin K3; vitamin C

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Zahedi, S. (2010). Are Mitochondria a Potential Target for Anti-Cancer Therapy in Carcinoid Tumors?. (Masters Thesis). University of Toledo Health Science Campus. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=mco1280427079

Chicago Manual of Style (16^th Edition):

Zahedi, Shadi. “Are Mitochondria a Potential Target for Anti-Cancer Therapy in Carcinoid Tumors?.” 2010. Masters Thesis, University of Toledo Health Science Campus. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=mco1280427079.

MLA Handbook (7^th Edition):

Zahedi, Shadi. “Are Mitochondria a Potential Target for Anti-Cancer Therapy in Carcinoid Tumors?.” 2010. Web. 17 Aug 2019.

Vancouver:

Zahedi S. Are Mitochondria a Potential Target for Anti-Cancer Therapy in Carcinoid Tumors?. [Internet] [Masters thesis]. University of Toledo Health Science Campus; 2010. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=mco1280427079.

Council of Science Editors:

Zahedi S. Are Mitochondria a Potential Target for Anti-Cancer Therapy in Carcinoid Tumors?. [Masters Thesis]. University of Toledo Health Science Campus; 2010. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=mco1280427079

20. Lee, Sang Hyeb. Computational Framework for Small Animal SPECT Imaging: Simulation and Reconstruction.

Degree: 2015, University of Tennessee – Knoxville

URL: https://trace.tennessee.edu/utk_graddiss/3346

► Small animal Single Photon Emission Computed Tomography (SPECT) has been an invaluable asset in biomedical science since this non-invasive imaging technique allows the longitudinal studies… (more)

Subjects/Keywords: Medical Imaging; SPECT; Reconstruction; Simulation; Attenuation and Scatter Correction; Computer Engineering; Nuclear; Numerical Analysis and Scientific Computing

10 more images…

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lee, S. H. (2015). Computational Framework for Small Animal SPECT Imaging: Simulation and Reconstruction. (Doctoral Dissertation). University of Tennessee – Knoxville. Retrieved from https://trace.tennessee.edu/utk_graddiss/3346

Chicago Manual of Style (16^th Edition):

Lee, Sang Hyeb. “Computational Framework for Small Animal SPECT Imaging: Simulation and Reconstruction.” 2015. Doctoral Dissertation, University of Tennessee – Knoxville. Accessed August 17, 2019. https://trace.tennessee.edu/utk_graddiss/3346.

MLA Handbook (7^th Edition):

Lee, Sang Hyeb. “Computational Framework for Small Animal SPECT Imaging: Simulation and Reconstruction.” 2015. Web. 17 Aug 2019.

Vancouver:

Lee SH. Computational Framework for Small Animal SPECT Imaging: Simulation and Reconstruction. [Internet] [Doctoral dissertation]. University of Tennessee – Knoxville; 2015. [cited 2019 Aug 17]. Available from: https://trace.tennessee.edu/utk_graddiss/3346.

Council of Science Editors:

Lee SH. Computational Framework for Small Animal SPECT Imaging: Simulation and Reconstruction. [Doctoral Dissertation]. University of Tennessee – Knoxville; 2015. Available from: https://trace.tennessee.edu/utk_graddiss/3346

University of Manchester

21. Sandoval Olive, Mario. 6DoF Mouse Integration for Scientific and Medical Visualisation.

Degree: 2016, University of Manchester

URL: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:296193

► With advances in medical imaging over the years, medical diagnosis, especially X-ray based examinations and ultrasonography, have become increasingly reliant on a range of 3D… (more)

Subjects/Keywords: Input Devices; 3D Volumetric Visualisation; Degrees of Freedom; Scientific Visualisation; Medical Imaging; Virtual Reality; 6DoF; Visualisation Volume Software

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sandoval Olive, M. (2016). 6DoF Mouse Integration for Scientific and Medical Visualisation. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:296193

Chicago Manual of Style (16^th Edition):

Sandoval Olive, Mario. “6DoF Mouse Integration for Scientific and Medical Visualisation.” 2016. Doctoral Dissertation, University of Manchester. Accessed August 17, 2019. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:296193.

MLA Handbook (7^th Edition):

Sandoval Olive, Mario. “6DoF Mouse Integration for Scientific and Medical Visualisation.” 2016. Web. 17 Aug 2019.

Vancouver:

Sandoval Olive M. 6DoF Mouse Integration for Scientific and Medical Visualisation. [Internet] [Doctoral dissertation]. University of Manchester; 2016. [cited 2019 Aug 17]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:296193.

Council of Science Editors:

Sandoval Olive M. 6DoF Mouse Integration for Scientific and Medical Visualisation. [Doctoral Dissertation]. University of Manchester; 2016. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:296193

22. Gaillard, Maxence. Les images du cerveau : epistémologie de l'usage de l'imagerie cérébrale en sciences cognitives : Images of brain, philosophy of brain imaging in cognitive science.

Degree: Docteur es, Philosophie, 2015, Lyon, École normale supérieure

URL: http://www.theses.fr/2015ENSL1023

►

Cette thèse d’épistémologie et d’histoire des sciences cognitives est consacrée à son niveau le plus général au problème de l’instrument scientifique, parent pauvre de la… (more)

▼

Cette thèse d’épistémologie et d’histoire des sciences cognitives est consacrée à son niveau le plus général au problème de l’instrument scientifique, parent pauvre de la réflexion sur l’investigation scientifique, et se concentre à titre particulier sur le développement des techniques d’imagerie cérébrale fonctionnelle et leur introduction dans le domaine cognitif au cours des années 1980-1990. Un choix motivé notamment par la nouveauté et l’importance de ce nouvel instrument, dont l’émergence est régulièrement comparée à celle du télescope au moment de la Révolution scientifique du XVIIe siècle. La première partie est ainsi consacrée à une analyse générale de l’instrument scientifique et des problèmes essentiels qu’il soulève. Elle propose un certain nombre d’hypothèses en réponse, et en examine les enjeux théoriques. La deuxième partie défend une interprétation historique de l’émergence des deux technologies d’imagerie fonctionnelle que sont la tomographie par émission de positons et l’imagerie par résonance magnétique fonctionnelle. En reprenant dans le détail certains éléments d’invention et de diffusion de ces techniques, elle montre notamment l’intrication des procédures de validation des instruments et des divers mécanismes scientifiques et sociétaux qui poussent à les développer puis à les utiliser. A la lumière des analyses théoriques et générales de la première, et sur la base de l’interprétation historique de la seconde, la troisième partie est dédiée à l’examen des implications de ces nouvelles technologies d’imagerie sur l’évolution du champ des sciences cognitives et de la reprise de leurs résultats dans d’autres domaines, tant scientifiques que technologiques ou pratiques. A ce double égard, elle défend la thèse générale que l’introduction de l’imagerie agit beaucoup moins comme un facteur de résolution de certaines questions que comme un facteur de déplacement de la problématique et de l’impact théorique et sociétal des sciences cognitives.

At a general level, this dissertation in philosophy and history of cognitive science is devoted to the underestimated problem of scientific instruments. It is focused on some functional brain imaging techniques introduced in the field of cognitive studies during the 1980’s and 1990’s, the impact of such new technologies being sometimes compared to an instrumental revolution, in a way similar to the impact of the invention of the telescope on post-Galilean astronomy. The first part consists in a philosophical and historical analysis of the notion of scientific instrument. In this regard, some issues are raises and some hypotheses are formulated. The second part presents an interpretation of the historical emergence of Positron Emission Tomography and functional Magnetic Resonance Imaging. Dealing with details of the invention and circulation of those techniques, it shows in particular the entanglement of the validation procedures of instruments with the various scientific and societal mechanisms driving to their development and use. Taking its roots in the…

Advisors/Committee Members: Roy, Jean-Michel (thesis director).

Subjects/Keywords: Instrument scientifique; Expérimentation; Imagerie cérébrale; Sciences cognitives; Neurosciences; TEP; IRMf; Scientific instruments; Experimentation; Brain imaging; Cognitive science; Neuroscience; PET; FMRI

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Gaillard, M. (2015). Les images du cerveau : epistémologie de l'usage de l'imagerie cérébrale en sciences cognitives : Images of brain, philosophy of brain imaging in cognitive science. (Doctoral Dissertation). Lyon, École normale supérieure. Retrieved from http://www.theses.fr/2015ENSL1023

Chicago Manual of Style (16^th Edition):

Gaillard, Maxence. “Les images du cerveau : epistémologie de l'usage de l'imagerie cérébrale en sciences cognitives : Images of brain, philosophy of brain imaging in cognitive science.” 2015. Doctoral Dissertation, Lyon, École normale supérieure. Accessed August 17, 2019. http://www.theses.fr/2015ENSL1023.

MLA Handbook (7^th Edition):

Gaillard, Maxence. “Les images du cerveau : epistémologie de l'usage de l'imagerie cérébrale en sciences cognitives : Images of brain, philosophy of brain imaging in cognitive science.” 2015. Web. 17 Aug 2019.

Vancouver:

Gaillard M. Les images du cerveau : epistémologie de l'usage de l'imagerie cérébrale en sciences cognitives : Images of brain, philosophy of brain imaging in cognitive science. [Internet] [Doctoral dissertation]. Lyon, École normale supérieure; 2015. [cited 2019 Aug 17]. Available from: http://www.theses.fr/2015ENSL1023.

Council of Science Editors:

Gaillard M. Les images du cerveau : epistémologie de l'usage de l'imagerie cérébrale en sciences cognitives : Images of brain, philosophy of brain imaging in cognitive science. [Doctoral Dissertation]. Lyon, École normale supérieure; 2015. Available from: http://www.theses.fr/2015ENSL1023

Rochester Institute of Technology

23. Park, Sung Ho. Rendering non-pictorial (Scientific) high dynamic range images.

Degree: School of Photographic Arts and Sciences (CIAS), 2004, Rochester Institute of Technology

URL: https://scholarworks.rit.edu/theses/5240

► In recent years, the graphics community is seeing an increasing demand for the capture and usage of high-dynamic-range (HDR) images. Since the production of HDR… (more)

▼ In recent years, the graphics community is seeing an increasing demand for the capture and usage of high-dynamic-range (HDR) images. Since the production of HDR imagery is not solely the domain of the visualization of real life or computer generated scenes, novel techniques are also required for imagery captured from non-visual sources such as remote sensing, medical imaging, astronomical imaging, etc. This research proposes to integrate the techniques used for the display of high-dynamic-range pictorial imagery for the practical visualization of non-pictorial (scientific) imagery for data mining and interpretation. Nine algorithms were utilized to overcome the problem associated with rendering the high-dynamic-range image data to low-dynamic-range display devices, and the results were evaluated using a psychophysical experiment. Two paired-comparison experiments and a target detection experiment were performed. Paired-comparison results indicate that the Zone System performs the best on average and the Local Color Correction method performs the worst. The results show that the performance of different encoding schemes depend on the type of data being visualized. The correlation between the preference and scientific usefulness judgments (R2 = 0.31) demonstrates that observers tend to use different criteria when judging the scientific usefulness versus image preference. The experiment was conducted using observers with expertise (Radiologists) for the Medical image to further elucidate the success of HDR rendering on these data. The results indicated that both Radiologists and Non-radiologists tend to use similar criteria regardless of their experience and expertise when judging the usefulness of rendered images. A target detection experiment was conducted to measure the detectability of an embedded noise target in the Medical image to demonstrate the effect of the tone mapping operators on target detection. The result of the target detection experiment illustrated that the detectability of targets the image is greatly influenced by the rendering algorithm due to the inherent differences in tone mapping among the algorithms. Advisors/Committee Members: Montag, Ethan, Fairchild, Mark.

Subjects/Keywords: High-dynamic-range images; Imaging science; Scientific use

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Park, S. H. (2004). Rendering non-pictorial (Scientific) high dynamic range images. (Thesis). Rochester Institute of Technology. Retrieved from https://scholarworks.rit.edu/theses/5240

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Park, Sung Ho. “Rendering non-pictorial (Scientific) high dynamic range images.” 2004. Thesis, Rochester Institute of Technology. Accessed August 17, 2019. https://scholarworks.rit.edu/theses/5240.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Park, Sung Ho. “Rendering non-pictorial (Scientific) high dynamic range images.” 2004. Web. 17 Aug 2019.

Vancouver:

Park SH. Rendering non-pictorial (Scientific) high dynamic range images. [Internet] [Thesis]. Rochester Institute of Technology; 2004. [cited 2019 Aug 17]. Available from: https://scholarworks.rit.edu/theses/5240.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Park SH. Rendering non-pictorial (Scientific) high dynamic range images. [Thesis]. Rochester Institute of Technology; 2004. Available from: https://scholarworks.rit.edu/theses/5240

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Wright State University

24. Ausdenmoore, Benjamin D. Synaptic contact localization in three dimensional space using a Center Distance Algorithm.

Degree: MS, Physiology and Neuroscience, 2011, Wright State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=wright1320866829

► Spatial distribution of synaptic inputs on the dendritic tree of a neuron can have significant influence on neuronal function. Consequently, accurate anatomical reconstructions of neuron… (more)

Subjects/Keywords: Anatomy and Physiology; Biology; Biomedical Engineering; Biomedical Research; Computer Science; Medical Imaging; Neurobiology; Neurology; Neurosciences; Physiology; Scientific Imaging; Confocal microscopy; Synapse localization; Dendrite; Tracing; Image analysis; Matlab; Skeleton

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ausdenmoore, B. D. (2011). Synaptic contact localization in three dimensional space using a Center Distance Algorithm. (Masters Thesis). Wright State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=wright1320866829

Chicago Manual of Style (16^th Edition):

Ausdenmoore, Benjamin D. “Synaptic contact localization in three dimensional space using a Center Distance Algorithm.” 2011. Masters Thesis, Wright State University. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=wright1320866829.

MLA Handbook (7^th Edition):

Ausdenmoore, Benjamin D. “Synaptic contact localization in three dimensional space using a Center Distance Algorithm.” 2011. Web. 17 Aug 2019.

Vancouver:

Ausdenmoore BD. Synaptic contact localization in three dimensional space using a Center Distance Algorithm. [Internet] [Masters thesis]. Wright State University; 2011. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=wright1320866829.

Council of Science Editors:

Ausdenmoore BD. Synaptic contact localization in three dimensional space using a Center Distance Algorithm. [Masters Thesis]. Wright State University; 2011. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=wright1320866829

Wright State University

25. Karvir, Hrishikesh. Design and Validation of a Sensor Integration and Feature Fusion Test-Bed for Image-Based Pattern Recognition Applications.

Degree: PhD, Engineering PhD, 2010, Wright State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=wright1291753291

► We integrated a sensor hardware test-bed using scientific grade, commercial off-the-shelf (COTS) technology and developed supporting software to enable rapid prototyping. The validity of… (more)

▼ We integrated a sensor hardware test-bed using scientific grade, commercial off-the-shelf (COTS) technology and developed supporting software to enable rapid prototyping. The validity of this test-bed and associated software was demonstrated through the delivery of a ground-based multispectral visual surveillance prototype for improvised explosive devices (IED) detection using electro-optical (EO) and short-wave infrared (SWIR) cameras. Software developed to support the test-bed included modules for image acquisition, preconditioning, segmentation, feature extraction, data regularization and pattern recognition. To provide spatially co-aligned data, we optimized a mutual information-based image registration algorithm to improve its convergence rate and benchmarked it against the established simplex method. For four different multimodal test image sets, our algorithm convergence success improved by 15 to 40% as compared to the downhill simplex method, albeit with an approximately four times higher computational cost. Additional strategies, such as bit-depth reduction, image down-sampling and gradient-based regions of interest (ROI) selection, were systematically evaluated and led to the registration of high resolution images at nearly 60 times faster than the standard approach. To automatically identify IED in the acquired multi-spectral imagery, four different pattern classifiers were tested; Bayes, k-nearest neighbor (knn-NN), support vector machines (SVM) and our novel piece-wise linear convex-hull classifier. Initial tests with the convex-hull classifier using simulated data indicated significant reduction in error rates of up to 89% (p=3e-6) when compared to the Bayes classifier. Subsequently, each of the four classifiers was tested using the IED data set that consisted of 154 different intensity-based and content-based features extracted from the EO and SWIR imagery. Salient features were selected using receiver operating characteristic (ROC) curve analysis and a wrapper-based process that used minimum error rate as the criterion function. A stratified 10-fold cross-validation analysis was used to compare classifier performances using t-tests with a 95% confidence interval. Under different operating conditions (OC), the generalized classification error rate ranged from 13.0% (±1.2) to 29.6% (±2.7). For six of the eight acquired data sets, the convex-hull classifier provided equivalent or lower (as compared to at least one other classifier) generalized error rate, used a lower number of features (at most 3), reduced training time (as compared to the knn-NN and SVM classifiers) and relied on lower function complexity. Concurrently, the class-label assignment time using the convex-hull approach was a factor of 10 lower than the Bayes classifier and a factor of 100 lower than the knn-NN and SVM classifiers. Considering the attributes of a good classifier, the convex-hull approach provided the overall best balance between the different measures of performance. Advisors/Committee Members: Skipper, Julie A. (Advisor).

Subjects/Keywords: Engineering; Remote Sensing; Scientific Imaging; Systems Design; Machine learning; Pattern classification; Target detection; Convex hull; Piecewise linear classifier; Image registration; Systems integration; Multi-sensor fusion; Multi-spectral imaging

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Karvir, H. (2010). Design and Validation of a Sensor Integration and Feature Fusion Test-Bed for Image-Based Pattern Recognition Applications. (Doctoral Dissertation). Wright State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=wright1291753291

Chicago Manual of Style (16^th Edition):

Karvir, Hrishikesh. “Design and Validation of a Sensor Integration and Feature Fusion Test-Bed for Image-Based Pattern Recognition Applications.” 2010. Doctoral Dissertation, Wright State University. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=wright1291753291.

MLA Handbook (7^th Edition):

Karvir, Hrishikesh. “Design and Validation of a Sensor Integration and Feature Fusion Test-Bed for Image-Based Pattern Recognition Applications.” 2010. Web. 17 Aug 2019.

Vancouver:

Karvir H. Design and Validation of a Sensor Integration and Feature Fusion Test-Bed for Image-Based Pattern Recognition Applications. [Internet] [Doctoral dissertation]. Wright State University; 2010. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=wright1291753291.

Council of Science Editors:

Karvir H. Design and Validation of a Sensor Integration and Feature Fusion Test-Bed for Image-Based Pattern Recognition Applications. [Doctoral Dissertation]. Wright State University; 2010. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=wright1291753291

McMaster University

26. Emond, Patrick D. Bone Erosion Measurement in Subjects with Rheumatoid Arthritis Using Magnetic Resonance Imaging.

Degree: PhD, 2012, McMaster University

URL: http://hdl.handle.net/11375/11789

►

Rheumatoid arthritis (RA) is a systemic disease that can affect the nervous system, lungs, heart, skin, reticuloendothelium and joints. Currently, the gold-standard measurement for… (more)

Subjects/Keywords: medical imaging; magnetic resonance imaging; rheumatoid arthritis; bone erosion; segmentation; Graphics and Human Computer Interfaces; Numerical Analysis and Scientific Computing; Other Physics; Radiology; Rheumatology; Graphics and Human Computer Interfaces

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Emond, P. D. (2012). Bone Erosion Measurement in Subjects with Rheumatoid Arthritis Using Magnetic Resonance Imaging. (Doctoral Dissertation). McMaster University. Retrieved from http://hdl.handle.net/11375/11789

Chicago Manual of Style (16^th Edition):

Emond, Patrick D. “Bone Erosion Measurement in Subjects with Rheumatoid Arthritis Using Magnetic Resonance Imaging.” 2012. Doctoral Dissertation, McMaster University. Accessed August 17, 2019. http://hdl.handle.net/11375/11789.

MLA Handbook (7^th Edition):

Emond, Patrick D. “Bone Erosion Measurement in Subjects with Rheumatoid Arthritis Using Magnetic Resonance Imaging.” 2012. Web. 17 Aug 2019.

Vancouver:

Emond PD. Bone Erosion Measurement in Subjects with Rheumatoid Arthritis Using Magnetic Resonance Imaging. [Internet] [Doctoral dissertation]. McMaster University; 2012. [cited 2019 Aug 17]. Available from: http://hdl.handle.net/11375/11789.

Council of Science Editors:

Emond PD. Bone Erosion Measurement in Subjects with Rheumatoid Arthritis Using Magnetic Resonance Imaging. [Doctoral Dissertation]. McMaster University; 2012. Available from: http://hdl.handle.net/11375/11789

Kent State University

27. Shokouhimehr, Mohammadreza. Prussian Blue Nanoparticles and its Analogues as New-Generation T1-Weighted MRI Contrast Agents for Cellular Imaging.

Degree: MS, College of Arts and Sciences / Department of Chemistry, 2010, Kent State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=kent1275612500

► There are insufficient achievements in the field of cancer diagnosis and treatment for new dual agents, which would provide health care specialists the ability… (more)

▼ There are insufficient achievements in the field of cancer diagnosis and treatment for new dual agents, which would provide health care specialists the ability to simultaneously image patients’ cancerous tissues as well as treat the diseases. Prussian blue (ferric hexacyanoferrate) is a nontoxic FDA approved compound used clinically as an antidote for thallium and radioactive cesium poisoning. In this thesis development of simple methods for the synthesis of biocompatible Prussian blue nanoparticles (PBNPs) and its analogues as well as their applications for magnetic resonance imaging (MRI) contrast agents and drug delivery have been studied. The extensive magnetic properties investigations show that Prussian blue nanoparticles and gadolinium doped analogue nanoparticles significantly shorten the T1 relaxation time in aqueous solution and in HeLa cells treated with PBNPs, demonstrating their potential use as MRI contrast agents. Although the relaxivity values of Prussian blue nanoparticles are approximately an order of magnitude lower than the typical commercial Gd3+-based T1 contrast agents but it is found to be comparable to the values obtained for the MnO nanoparticles-based T1 agents. In order to provide high contrast, gadolinium doped Prussian blue nanoparticles (Gd-PBNPs) were prepared. It was also found that the Gd-PBNPs can shorten the T1 relaxation time significantly and provide potential use for clinical applications. In order for Prussian blue and its analogues nanoparticles to be concurrently utilized as drug delivery agents they must be biocompatible and capable of crossing the plasma membrane. Therefore, Prussian blue nanoparticles and related analogues were synthesized and functionalized by carboxylic acids such as citric acid as capping agents to control size distribution. To study the intracellular uptake of Prussian blue and analogue nanoparticles, their surfaces were functionalized separately with the small molecule dyes such as 5-carboxyfluorescein and Alexa Fluor® 350 cadaverine, as well as the anticancer agent. Confocal fluorescence imaging of HeLa cells treated with the functionalized nanoparticles shows fluorescent signals in the cells suggesting intracellular uptake of the Prussian blue and Gd-PB nanoparticles. The HeLa cells internalized Prussian blue nanoparticles and gadolinium-containing Prussian blue nanoparticles could also enhance the T1 MRI contrast. The results clearly show that these nanoparticles can be used as an effective T1 contrast agent for cellular imaging. Functionalized Prussian blue nanoparticles and related analogues with both MRI contrast and drug delivery capabilities may become powerful dual agents for simultaneous cancer treatment and assessment of treatment effectiveness. Advisors/Committee Members: Huang, Songping D. (Advisor).

Subjects/Keywords: Biochemistry; Biology; Biomedical Research; Biophysics; Chemical Engineering; Chemistry; Molecular Biology; Organic Chemistry; Pharmaceuticals; Pharmacology; Polymers; Radiology; Scientific Imaging; Therapy; Prussian blue; coordination polymers; gadolinium; nanoparticles; imaging agents; contrast agents; magnetic resonance imaging; molecular imaging; relaxivity; drug delivery; magnetic properties

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Shokouhimehr, M. (2010). Prussian Blue Nanoparticles and its Analogues as New-Generation T1-Weighted MRI Contrast Agents for Cellular Imaging. (Masters Thesis). Kent State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=kent1275612500

Chicago Manual of Style (16^th Edition):

Shokouhimehr, Mohammadreza. “Prussian Blue Nanoparticles and its Analogues as New-Generation T1-Weighted MRI Contrast Agents for Cellular Imaging.” 2010. Masters Thesis, Kent State University. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=kent1275612500.

MLA Handbook (7^th Edition):

Shokouhimehr, Mohammadreza. “Prussian Blue Nanoparticles and its Analogues as New-Generation T1-Weighted MRI Contrast Agents for Cellular Imaging.” 2010. Web. 17 Aug 2019.

Vancouver:

Shokouhimehr M. Prussian Blue Nanoparticles and its Analogues as New-Generation T1-Weighted MRI Contrast Agents for Cellular Imaging. [Internet] [Masters thesis]. Kent State University; 2010. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=kent1275612500.

Council of Science Editors:

Shokouhimehr M. Prussian Blue Nanoparticles and its Analogues as New-Generation T1-Weighted MRI Contrast Agents for Cellular Imaging. [Masters Thesis]. Kent State University; 2010. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=kent1275612500

Texas Medical Center

28. Ahmad, Moiz. Design and Optimization of Four-dimensional Cone-beam Computed Tomography in Image-guided Radiation Therapy.

Degree: PhD, 2012, Texas Medical Center

URL: http://digitalcommons.library.tmc.edu/utgsbs_dissertations/312

► The influence of respiratory motion on patient anatomy poses a challenge to accurate radiation therapy, especially in lung cancer treatment. Modern radiation therapy planning… (more)

Subjects/Keywords: Medical imaging; lung imaging; radiation therapy; IGRT; image reconstruction; cone-beam CT; 4D imaging; 4D-CBCT; VOI; GSBS; Analytical, Diagnostic and Therapeutic Techniques and Equipment; Medicine and Health Sciences; Numerical Analysis and Scientific Computing; Physics

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ahmad, M. (2012). Design and Optimization of Four-dimensional Cone-beam Computed Tomography in Image-guided Radiation Therapy. (Doctoral Dissertation). Texas Medical Center. Retrieved from http://digitalcommons.library.tmc.edu/utgsbs_dissertations/312

Chicago Manual of Style (16^th Edition):

Ahmad, Moiz. “Design and Optimization of Four-dimensional Cone-beam Computed Tomography in Image-guided Radiation Therapy.” 2012. Doctoral Dissertation, Texas Medical Center. Accessed August 17, 2019. http://digitalcommons.library.tmc.edu/utgsbs_dissertations/312.

MLA Handbook (7^th Edition):

Ahmad, Moiz. “Design and Optimization of Four-dimensional Cone-beam Computed Tomography in Image-guided Radiation Therapy.” 2012. Web. 17 Aug 2019.

Vancouver:

Ahmad M. Design and Optimization of Four-dimensional Cone-beam Computed Tomography in Image-guided Radiation Therapy. [Internet] [Doctoral dissertation]. Texas Medical Center; 2012. [cited 2019 Aug 17]. Available from: http://digitalcommons.library.tmc.edu/utgsbs_dissertations/312.

Council of Science Editors:

Ahmad M. Design and Optimization of Four-dimensional Cone-beam Computed Tomography in Image-guided Radiation Therapy. [Doctoral Dissertation]. Texas Medical Center; 2012. Available from: http://digitalcommons.library.tmc.edu/utgsbs_dissertations/312

Case Western Reserve University

29. Derakhshan, Jamal Jon. Innovations Involving Balanced Steady State Free Precession MRI.

Degree: PhD, Biomedical Engineering, 2009, Case Western Reserve University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=case1247256364

► MRI provides different types of exquisite soft tissue and functional contrast. However, depending on the desired contrast and spatial resolution properties, the acquisition time… (more)

▼ MRI provides different types of exquisite soft tissue and functional contrast. However, depending on the desired contrast and spatial resolution properties, the acquisition time can be quite long. The long-term objective of this work is to improve methods to quickly and accurately diagnose human disease using MRI and provide resources that can be used for image-guided therapy and real-time imaging. Balanced steady state free precession (bSSFP) or True-FISP provides the highest signal-to-noise ratio efficiency of any pulse sequence. However, in bSSFP, contrast is a mixture of T1 and T2 weightings, which is often not desired clinically, and the signal from flowing blood is hyperintense, which can obscure the vessel wall and create artifacts. Also, there are obstructive saturation band artifacts at intersections of rapidly-acquired multiplanar images. The objective of this work was to modify the magnetization preparation and readout properties of the bSSFP sequence to: 1) improve methods that eliminate T1 and isolate T2 contrast, 2) suppress the signal from flowing blood, and 3) characterize and reduce the saturation banding artifacts. A new T-One insensitive Steady State Imaging (TOSSI)-bSSFP combined acquisition technique, Resolution Enhanced TOSSI (RE-TOSSI), has been developed by using a partial Fourier acquisition and eliminating the inversion pulses from TOSSI after the data around the center of k-space is acquired. Results show that TOSSI contrast is maintained, while spatial resolution degradation is reduced. Additional benefits include reduced RF power deposition and faster imaging time. Application to high-resolution, non-subtraction thermal ablation monitoring is demonstrated. An improved dark blood bSSFP pulse sequence (HEFEWEIZEN) has been developed by introducing spatial saturation in True-FISP. This method does not increase the repetition time (TR) or substantially alter stationary tissue contrast and allows for directional suppression of blood flow (e.g. arterial vs. venous). Comparison to diffusion-prepared SSFP in the common carotid artery demonstrated significantly improved vessel wall-lumen contrast-to-noise ratio efficiency (p = 0.02). Intersecting-plane saturation band artifacts were characterized in three common steady-state pulse sequences (FLASH, FISP, and bSSFP). Substantial temporal and pulse sequence dependencies were found. Reverse centric phase encoding is demonstrated to be a simple and effective way of minimizing this artifact. Advisors/Committee Members: Duerk, Jeffrey (Advisor).

Subjects/Keywords: Biomedical Research; Engineering; Health Care; Physics; Radiology; Scientific Imaging; Surgery; Medical Imaging; MRI; bSSFP; TrueFISP; RE-TOSSI; HEFEWEIZEN; Rapid Imaging; Pulse Sequence; T2-weighted; Dark Blood; multiplanar; saturation band; FLASH; Resolution Enhanced TOSSI; Zeugmatographic Encoding; thermal ablation; carotid artery; vessel wall

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Derakhshan, J. J. (2009). Innovations Involving Balanced Steady State Free Precession MRI. (Doctoral Dissertation). Case Western Reserve University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=case1247256364

Chicago Manual of Style (16^th Edition):

Derakhshan, Jamal Jon. “Innovations Involving Balanced Steady State Free Precession MRI.” 2009. Doctoral Dissertation, Case Western Reserve University. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1247256364.

MLA Handbook (7^th Edition):

Derakhshan, Jamal Jon. “Innovations Involving Balanced Steady State Free Precession MRI.” 2009. Web. 17 Aug 2019.

Vancouver:

Derakhshan JJ. Innovations Involving Balanced Steady State Free Precession MRI. [Internet] [Doctoral dissertation]. Case Western Reserve University; 2009. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1247256364.

Council of Science Editors:

Derakhshan JJ. Innovations Involving Balanced Steady State Free Precession MRI. [Doctoral Dissertation]. Case Western Reserve University; 2009. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1247256364

Case Western Reserve University

30. FEI, Baowei. Image Registration for the Prostate.

Degree: PhD, EECS - System and Control Engineering, 2008, Case Western Reserve University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=case1224274091

► The long-term goal of this research is to develop medical image registration techniques that can improve cancer detection, diagnosis, and therapy. Both rigid-body and deformable… (more)

▼ The long-term goal of this research is to develop medical image registration techniques that can improve cancer detection, diagnosis, and therapy. Both rigid-body and deformable image registration methods were developed for human magnetic resonance (MR) images. As reported in Chapter 2, our automatic, three-dimensional (3D), rigid-body registration method has special features that include multi-resolution, multi-similarity, and restarting mechanisms. These features improved the robustness of MR image registration. The automatic registration method has been evaluated for potential applications in prostate MR imaging. However, tissue deformation and patient positions often raise problems for rigid-body registration. In order to improve registration accuracy, 3D thin-plate spline (TPS)-based deformable registration methods were developed and evaluated for pelvic MR images that were acquired at different patient positions/conditions. As described in Chapter 3, our TPS registration methods have several potential applications for image-guided therapy of the prostate. With the recent advancement of small animal imaging technology, MR imaging can provide high-resolution images of a tumor with subtle anatomic details, molecular imaging such as positron emission tomography (PET) can provide functional and metabolic information regarding the tumor. Registration of PET and MR images can combine the strength from the two imaging modalities and thus provides complementary information at the cellular and molecular levels. Chapter 4 proposes and evaluates a finite-element model (FEM)-based registration method for tumor PET and MR images, which can have unique applications in cancer early detection and therapy assessment. Chapter 5 further demonstrates clinical applications of multimodality image registration for prostate cancer patients. Methods were developed for MRI/SPECT registration and CT/SPECT fusion. Finally, Chapter 6 describes the future work of image registration techniques and the conclusion of the research work. Advisors/Committee Members: Loparo, Kenneth (Committee Chair).

Subjects/Keywords: Computer Science; Engineering; Radiology; Scientific Imaging; image registration; deformable registration; non-rigid registration; thin plate spline; finite element model; prostate cancer; image-guided therapy; magnetic resonance imaging (MRI); positron emission tomography (PET); molecular imaging

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

FEI, B. (2008). Image Registration for the Prostate. (Doctoral Dissertation). Case Western Reserve University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=case1224274091

Chicago Manual of Style (16^th Edition):

FEI, Baowei. “Image Registration for the Prostate.” 2008. Doctoral Dissertation, Case Western Reserve University. Accessed August 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1224274091.

MLA Handbook (7^th Edition):

FEI, Baowei. “Image Registration for the Prostate.” 2008. Web. 17 Aug 2019.

Vancouver:

FEI B. Image Registration for the Prostate. [Internet] [Doctoral dissertation]. Case Western Reserve University; 2008. [cited 2019 Aug 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1224274091.

Council of Science Editors:

FEI B. Image Registration for the Prostate. [Doctoral Dissertation]. Case Western Reserve University; 2008. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1224274091

		in
And / Or
		in
And / Or
		in
And / Or
		in

Open Access Theses and Dissertations