subject:(SONNENATMOSPH RE ASTRONOMIE )

Ruhr Universität Bochum

1. Dörr, Mathias. Star formation in RCW38.

Degree: 2012, Ruhr Universität Bochum

URL: http://nbn-resolving.de/urn/resolver.pl?urn=urn:nbn:de:hbz:294-35683

► Untersuchung des Sternentstehungsgebietes RCW38 über 3 Monate in J,H und K mit dem IRIS-Teleskop der Universitätssternwarte Bochum in Chile. Gewinnung von 40 Datenpunkten, mittels derer… (more)

Subjects/Keywords: Astronomie; Stern; Infrarot; Variabilität; Molekülwolke

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APA (6^th Edition):

Dörr, M. (2012). Star formation in RCW38. (Thesis). Ruhr Universität Bochum. Retrieved from http://nbn-resolving.de/urn/resolver.pl?urn=urn:nbn:de:hbz:294-35683

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Dörr, Mathias. “Star formation in RCW38.” 2012. Thesis, Ruhr Universität Bochum. Accessed December 06, 2019. http://nbn-resolving.de/urn/resolver.pl?urn=urn:nbn:de:hbz:294-35683.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Dörr, Mathias. “Star formation in RCW38.” 2012. Web. 06 Dec 2019.

Vancouver:

Dörr M. Star formation in RCW38. [Internet] [Thesis]. Ruhr Universität Bochum; 2012. [cited 2019 Dec 06]. Available from: http://nbn-resolving.de/urn/resolver.pl?urn=urn:nbn:de:hbz:294-35683.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Dörr M. Star formation in RCW38. [Thesis]. Ruhr Universität Bochum; 2012. Available from: http://nbn-resolving.de/urn/resolver.pl?urn=urn:nbn:de:hbz:294-35683

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

City University London

2. Filippaki, Evangelia. Glistenings in intraocular lenses and their effect on forward light scatter : an in vitro study.

Degree: PhD, 2015, City University London

URL: http://openaccess.city.ac.uk/13594/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.681379

► Introduction. Glistenings are fluid-filled inclusions in the polymer matrix of an intraocular lens (IOL). Acting as refractile particles they may contribute to a reported high… (more)

▼ Introduction. Glistenings are fluid-filled inclusions in the polymer matrix of an intraocular lens (IOL). Acting as refractile particles they may contribute to a reported high level of forward light scatter. However, several studies have reported that there is no significant correlation with a number of measures of visual function. The purpose of the work reported in this thesis was to test if there was an association between in vitro forward light scatter and grade of glistenings. The in vitro approach allows measurement of forward light scatter without the confounding effects of other structures in the eye and subjective responses. Methods. Intraocular lenses were placed at the centre of rotation of a detector stage. The detector measured the forward scattered light in star space at 37 angles covering ±18 degrees. Measurements were made for each of the test lenses at 3mm, 4mm and 5mm pupil sizes. Forward light scatter was quantified by calculating the straylight (volume under the scatter function) for the large angle domain (> 1 deg.). Images of the intraocular lenses were captured with a digital Nikon FS-2 photo slit-lamp. Having developed a Glistenings Detection Programme (GDP) in collaboration with external computer scientists, images were analysed. Results of glistening detection, which included their number, size, density and distribution, were correlated with in vitro forward light scatter measurements. Results. A statistically significant correlation was found between forward light scatter and the number, size and density of glistenings. Comparing our scatter results with the CIE standards, suggests that only high glistenings severity could have an impact on visual function. In addition, results were inversely proportional to pupil size due to the non-uniform distribution of glistenings. The shape of glistenings was shown to be predominantly ellipsoidal rather than spherical. Size and number of glistenings varies in the hydrophobic acrylic materials. Despite the production of new glistenings-free materials, development of glistenings may still exist with cases of high severity giving straylight parameter values greater than those for a cortical cataract subject. A statistically significant difference in MTF and Resolution limit was found in IOLs, pre and post thermal treatment. Finally, a correlation between IOL dioptric power and severity of glistenings was found. Conclusion. Subjective methods for grading intraocular lens glistenings poorly describe the significance of increased light scattering. Image processing software can provide objective data on glistenings density, size and morphology, factors which are important in light scatter modelling. The impact of glistenings on visual function needs further clinical investigation.

Subjects/Keywords: RE Ophthalmology

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APA (6^th Edition):

Filippaki, E. (2015). Glistenings in intraocular lenses and their effect on forward light scatter : an in vitro study. (Doctoral Dissertation). City University London. Retrieved from http://openaccess.city.ac.uk/13594/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.681379

Chicago Manual of Style (16^th Edition):

Filippaki, Evangelia. “Glistenings in intraocular lenses and their effect on forward light scatter : an in vitro study.” 2015. Doctoral Dissertation, City University London. Accessed December 06, 2019. http://openaccess.city.ac.uk/13594/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.681379.

MLA Handbook (7^th Edition):

Filippaki, Evangelia. “Glistenings in intraocular lenses and their effect on forward light scatter : an in vitro study.” 2015. Web. 06 Dec 2019.

Vancouver:

Filippaki E. Glistenings in intraocular lenses and their effect on forward light scatter : an in vitro study. [Internet] [Doctoral dissertation]. City University London; 2015. [cited 2019 Dec 06]. Available from: http://openaccess.city.ac.uk/13594/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.681379.

Council of Science Editors:

Filippaki E. Glistenings in intraocular lenses and their effect on forward light scatter : an in vitro study. [Doctoral Dissertation]. City University London; 2015. Available from: http://openaccess.city.ac.uk/13594/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.681379

City University London

3. Koller, Anton W. The friction coefficient of soft contact lens surfaces in relation to comfort and performance.

Degree: PhD, 2014, City University London

URL: http://openaccess.city.ac.uk/13791/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.681366

► The soft contact lenses of today are made from a variety of hydrogel materials. These materials have different properties in terms of water content, monomers,… (more)

▼ The soft contact lenses of today are made from a variety of hydrogel materials. These materials have different properties in terms of water content, monomers, hardness and other tensile characteristics. It is likely that the frictional properties also vary between materials. It is known that constituents of the tear film interact with contact lens materials to form a biofilm on the lens surface. The hypothesis of this research is that although the frictional properties of lens materials may vary these properties do not affect the comfort and performance of the lenses in vivo. A tribometer is a device to measure the coefficient of friction of materials. There was no commercially available tribometer designed specifically for use with contact lens materials, so one was constructed and validated against standard solid materials. The same equipment was used to determine the friction coefficients of five contemporary soft lens materials under different conditions of lubrication but, unlike other tribometers, this unique design simulated human blinking as far as possible. The experimental friction coefficients varied widely from 0.27 to 5.89 under different conditions of lubrication. The largest variation between materials was seen using the most viscous lubricant. For the in vivo studies the author coordinated the manufacture of 250 contact lenses, which were lathe cut and polished to a standard design, achieving exceptionally tight tolerances, using the same five materials. This rigourous process was carried out to minimise variations in the geometry of each contact lens. Subjects were screened to minimise ocular heterogeneities between subjects. Clinical performance of each lens was assessed using comfort, contrast sensitivity, visual acuity, entoptic phenomena, non-invasive tear break-up time and lens movement on the eye. In a clinical environment none of these parameters showed any associations with the coefficients of friction found in vitro, apart from a moderate correlation (rho = 0.5) between lens movement and the coefficient of friction under borderline friction conditions. In conclusion, the findings of this research support the hypothesis that frictional properties of soft lenses do not affect comfort and performance in vivo.

Subjects/Keywords: RE Ophthalmology

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APA (6^th Edition):

Koller, A. W. (2014). The friction coefficient of soft contact lens surfaces in relation to comfort and performance. (Doctoral Dissertation). City University London. Retrieved from http://openaccess.city.ac.uk/13791/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.681366

Chicago Manual of Style (16^th Edition):

Koller, Anton W. “The friction coefficient of soft contact lens surfaces in relation to comfort and performance.” 2014. Doctoral Dissertation, City University London. Accessed December 06, 2019. http://openaccess.city.ac.uk/13791/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.681366.

MLA Handbook (7^th Edition):

Koller, Anton W. “The friction coefficient of soft contact lens surfaces in relation to comfort and performance.” 2014. Web. 06 Dec 2019.

Vancouver:

Koller AW. The friction coefficient of soft contact lens surfaces in relation to comfort and performance. [Internet] [Doctoral dissertation]. City University London; 2014. [cited 2019 Dec 06]. Available from: http://openaccess.city.ac.uk/13791/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.681366.

Council of Science Editors:

Koller AW. The friction coefficient of soft contact lens surfaces in relation to comfort and performance. [Doctoral Dissertation]. City University London; 2014. Available from: http://openaccess.city.ac.uk/13791/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.681366

Cardiff University

4. Hiscox, Rachel Joy. The retina in cystic fibrosis.

Degree: PhD, 2013, Cardiff University

URL: http://orca.cf.ac.uk/59738/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610988

► Cystic fibrosis (CF) is caused by defective function of CF Transmembrane Conductance Regulator (CFTR), an epithelial ion channel that facilitates chloride secretion. Previous research has… (more)

Subjects/Keywords: RE Ophthalmology

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APA (6^th Edition):

Hiscox, R. J. (2013). The retina in cystic fibrosis. (Doctoral Dissertation). Cardiff University. Retrieved from http://orca.cf.ac.uk/59738/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610988

Chicago Manual of Style (16^th Edition):

Hiscox, Rachel Joy. “The retina in cystic fibrosis.” 2013. Doctoral Dissertation, Cardiff University. Accessed December 06, 2019. http://orca.cf.ac.uk/59738/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610988.

MLA Handbook (7^th Edition):

Hiscox, Rachel Joy. “The retina in cystic fibrosis.” 2013. Web. 06 Dec 2019.

Vancouver:

Hiscox RJ. The retina in cystic fibrosis. [Internet] [Doctoral dissertation]. Cardiff University; 2013. [cited 2019 Dec 06]. Available from: http://orca.cf.ac.uk/59738/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610988.

Council of Science Editors:

Hiscox RJ. The retina in cystic fibrosis. [Doctoral Dissertation]. Cardiff University; 2013. Available from: http://orca.cf.ac.uk/59738/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610988

City University London

5. Ctori, I. Ethnic differences in the spatial distribution of macular pigment and its association with foveal anatomy.

Degree: PhD, 2016, City University London

URL: http://openaccess.city.ac.uk/14612/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.685584

► Macular pigment (MP) at the centre of the retina is thought to serve a protective function shielding the photoreceptors from damaging effects of blue light.… (more)

▼ Macular pigment (MP) at the centre of the retina is thought to serve a protective function shielding the photoreceptors from damaging effects of blue light. The amount of MP and its spatial density distribution across the macula i.e. its spatial profile varies among individuals. Lower levels of MP and certain MP spatial profile phenotypes are believed to be associated with increased risk of age-related macular degeneration (AMD). There is suggestion that MP spatial profiles differ between ethnicities, with non-exponential profiles occurring more frequently in non-whites. This may explain some of the ethnic variations seen in AMD prevalence. However, previous investigations have used several methodologies to measure MP. In addition, inconsistent MP spatial profile definitions have been used; thus comparing data between studies is difficult. Nevertheless, it has been hypothesised that variations in MP spatial distribution could be due to differences in foveal architecture, in particular at the foveal centre where MP levels peak. A study was designed to investigate the effect of ethnicity on MP spatial density distribution and its relation to foveal architecture. The influence of known risk factors for AMD was also considered. Young (18 to 39 years), healthy volunteers of white (n = 76), South Asian (n = 80) and black (n = 70) ethnic origin were recruited to take part. MP measurements were obtained using a method based on heterochromatic flicker photometry (HFP) and foveal morphology measurements were taken from optical coherence tomography (OCT) scans. The coefficients of repeatability of each of these were confirmed in a sub-study. A systematic objective MP spatial profile classification technique was implemented throughout. The feasibility of applying this to MP measurements obtained with different techniques such as HFP and fundus autofluorescence (FAF) was also explored in a sub-study. The results showed that measures of MP optical density (MPOD) over the central retinal area were statistically significantly increased in South Asian and black compared to white subjects, whereby ethnicity explained around 10% of the variation (P < 0.0005). Non-exponential MP spatial profiles (ring-like and central dip respectively) were significantly more prevalent in South Asian and black compared with white subjects (χ2 (4, n = 226) = 13.4, P = 0.009). Integrated MPOD up to 1.8º was significantly increased in ring-like and central dip compared to exponential profiles (P < 0.0005) irrespective of ethnicity. South Asian and black individuals presented thinner central retinas and wider foveas compared to white individuals (P < 0.0005). However, while accounting for these ethnic variations, foveal architecture provided no predictive values for the MP spatial profile phenotype.

Subjects/Keywords: RE Ophthalmology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ctori, I. (2016). Ethnic differences in the spatial distribution of macular pigment and its association with foveal anatomy. (Doctoral Dissertation). City University London. Retrieved from http://openaccess.city.ac.uk/14612/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.685584

Chicago Manual of Style (16^th Edition):

Ctori, I. “Ethnic differences in the spatial distribution of macular pigment and its association with foveal anatomy.” 2016. Doctoral Dissertation, City University London. Accessed December 06, 2019. http://openaccess.city.ac.uk/14612/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.685584.

MLA Handbook (7^th Edition):

Ctori, I. “Ethnic differences in the spatial distribution of macular pigment and its association with foveal anatomy.” 2016. Web. 06 Dec 2019.

Vancouver:

Ctori I. Ethnic differences in the spatial distribution of macular pigment and its association with foveal anatomy. [Internet] [Doctoral dissertation]. City University London; 2016. [cited 2019 Dec 06]. Available from: http://openaccess.city.ac.uk/14612/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.685584.

Council of Science Editors:

Ctori I. Ethnic differences in the spatial distribution of macular pigment and its association with foveal anatomy. [Doctoral Dissertation]. City University London; 2016. Available from: http://openaccess.city.ac.uk/14612/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.685584

City University London

6. Dabasia, Priya. A study of the role of advanced technologies in glaucoma case-finding.

Degree: PhD, 2014, City University London

URL: http://openaccess.city.ac.uk/12364/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.659282

► In the UK, 11,000 new cases of open angle glaucoma (OAG) are diagnosed annually in people aged 40 to 70 years. However, two-thirds of UK… (more)

▼ In the UK, 11,000 new cases of open angle glaucoma (OAG) are diagnosed annually in people aged 40 to 70 years. However, two-thirds of UK OAG cases may remain undiagnosed, highlighting the need for improved detection. UK optometrists generate more than 95% of referrals for suspected glaucoma and ocular hypertension. Case-detection of glaucoma may be improved by using screening tests with better diagnostic accuracy, but standardised protocols for advanced technologies used alone, or in combination, to detect glaucoma are lacking. Chapter 2 reports on two cross-sectional surveys of UK community optometrists, determining the equipment and information technology (IT) used in optometric practice, and exploring the rationale behind the uptake of ophthalmic equipment and IT. UK optometrists are increasingly investing in new ophthalmic equipment and IT, including the latest technology. Longitudinal comparisons with previous surveys revealed an increase in use of Optical coherence tomography (OCT), Goldmann/Perkins tonometry and pachymetry. Variations in responses reflected differences in General Ophthalmic Services provision across the UK and involvement in community enhanced services. There was general agreement that specialised equipment enhances clinical care and permits increased involvement in enhanced services, but initial costs and ongoing maintenance can be a financial burden. Chapter 3 summarises a prospective cross-sectional study investigating the diagnostic accuracy of four advanced technologies for detecting POAG, used alone and in combination, in a representative sample (N=505) of the UK primary care population aged ≥60 years, and compared to a reference standard ophthalmic examination. Structural imaging using the iVue SD-OCT provided better discrimination between POAG and non-POAG/non-OHT subjects than either visual function test (Frequency Doubling Technology or Moorfields Motion Displacement Threshold). The low specificity of visual function tests precludes their use in isolation, but their use together with objective evaluation of optic nerve head structure by SD-OCT should improve case-detection of glaucoma. Chapter 4 describes a case-control study (N=78) evaluating the diagnostic effectiveness of two slit-lamp based techniques (van Herick and Smith’s) and imaging-based systems (Pentacam and Visante OCT) when compared to the reference standard gonioscopic observation, to screen for individuals at-risk of angle closure glaucoma (ACG). Overall, the van Herick test and Visante OCT, used either alone or in combination, showed best discrimination between narrow and open angles. Recording of either the temporal or nasal van Herick grade would be sufficient for case-finding in at-risk individuals. Chapter 5 summarises preceding chapters and details recommendations for future research.

Subjects/Keywords: RE Ophthalmology

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APA (6^th Edition):

Dabasia, P. (2014). A study of the role of advanced technologies in glaucoma case-finding. (Doctoral Dissertation). City University London. Retrieved from http://openaccess.city.ac.uk/12364/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.659282

Chicago Manual of Style (16^th Edition):

Dabasia, Priya. “A study of the role of advanced technologies in glaucoma case-finding.” 2014. Doctoral Dissertation, City University London. Accessed December 06, 2019. http://openaccess.city.ac.uk/12364/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.659282.

MLA Handbook (7^th Edition):

Dabasia, Priya. “A study of the role of advanced technologies in glaucoma case-finding.” 2014. Web. 06 Dec 2019.

Vancouver:

Dabasia P. A study of the role of advanced technologies in glaucoma case-finding. [Internet] [Doctoral dissertation]. City University London; 2014. [cited 2019 Dec 06]. Available from: http://openaccess.city.ac.uk/12364/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.659282.

Council of Science Editors:

Dabasia P. A study of the role of advanced technologies in glaucoma case-finding. [Doctoral Dissertation]. City University London; 2014. Available from: http://openaccess.city.ac.uk/12364/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.659282

City University London

7. Turola, Massimo. Investigation of plenoptic imaging systems : a wave optics approach.

Degree: PhD, 2016, City University London

URL: http://openaccess.city.ac.uk/15183/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.690989

► Conventional imaging devices only capture a part of the total information carried by the light. A new generation of imaging devices, plenoptic systems, use an… (more)

▼ Conventional imaging devices only capture a part of the total information carried by the light. A new generation of imaging devices, plenoptic systems, use an array of micro lenses to codify the light coming from an object into a four dimensional function called the light field. The final image is then obtained after post processing computations on the light field. In this work plenoptic imaging devices are analysed using a wave optics approach. A platform to simulate light propagating under the Fresnel approximation in a generic optical system was developed in MATLAB. An optical system can be modelled as the composition of two basic operators: the free space propagation and the lens. The first one was implemented developing an original method derived from the angular spectrum of plane waves theory of propagation. The second was implemented using a phase mask. The code was developed to optimize the signal to noise ratio and the computational time. Two different configurations of plenoptic imaging systems were simulated. The first is the plenoptic 1.0 configuration. The general theory of plenoptic 1.0 and the post processing algorithms presented in the literature were verified using the simulation platform. The effects of diffraction were also evaluated and an original refocusing method is presented. For the second configuration, plenoptic 2.0, a full study of the optical resolution has been made and a detailed analysis of the effects of diffraction is presented. The results achieved with the simulations have been used to design a working prototype of a plenoptic microscope. This novel wave optics approach enables us to quantify for the first time in the literature the effects of diffraction on this class of devices. In plenoptic 1.0 diffraction is a source of noise due to the crosstalk between neighbouring lenslets. In plenoptic 2.0 systems the optical resolution is directly proportional to the magnification of the lenslet array. A small magnification leads to a high directional sampling but at the same time to a loss of optical resolution. The finite dimensions of the lenslets together with the wave nature of light produce a physical limit to the amount of information that can be achieved sampling the optical fields with those kind of devices.

Subjects/Keywords: RE Ophthalmology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Turola, M. (2016). Investigation of plenoptic imaging systems : a wave optics approach. (Doctoral Dissertation). City University London. Retrieved from http://openaccess.city.ac.uk/15183/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.690989

Chicago Manual of Style (16^th Edition):

Turola, Massimo. “Investigation of plenoptic imaging systems : a wave optics approach.” 2016. Doctoral Dissertation, City University London. Accessed December 06, 2019. http://openaccess.city.ac.uk/15183/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.690989.

MLA Handbook (7^th Edition):

Turola, Massimo. “Investigation of plenoptic imaging systems : a wave optics approach.” 2016. Web. 06 Dec 2019.

Vancouver:

Turola M. Investigation of plenoptic imaging systems : a wave optics approach. [Internet] [Doctoral dissertation]. City University London; 2016. [cited 2019 Dec 06]. Available from: http://openaccess.city.ac.uk/15183/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.690989.

Council of Science Editors:

Turola M. Investigation of plenoptic imaging systems : a wave optics approach. [Doctoral Dissertation]. City University London; 2016. Available from: http://openaccess.city.ac.uk/15183/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.690989

Cardiff University

8. Garcia Sanchez, Yaiza. Analysis of retinal image quality for peripheral vision in humans and pigeons (Columba livia).

Degree: PhD, 2012, Cardiff University

URL: http://orca.cf.ac.uk/41966/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567444

► Retinal image quality for peripheral as well as central visual field locations has been investigated in humans and an animal model (Columba livia) with wide-… (more)

▼ Retinal image quality for peripheral as well as central visual field locations has been investigated in humans and an animal model (Columba livia) with wide- angle, panoramic vision because of its laterally oriented eyes. The goal was to determine whether the retinal image is maintained at a higher quality away from the fovea in pigeons as compared to humans. In this thesis, the HSWFS (Hart- mann Shack Wavefront Sensor) has been implemented with the correspondent validation and application for measuring ocular aberrations in the human and avian eye. Using a modified HSWFS, the refractive error and total amount of ocular aberra- tions were measured for 20 pigeons along the horizontal meridian and for another 8 pigeons in the vertical meridian at three positions along the horizontal meridian. The HOA( High order aberrations) of 10 humans were measured at peripheral locations (±35 ◦) in the upper visual field and along the horizontal meridian. The anaesthetized animal’s head position was controlled by a stereotaxic head holder capable of horizontal and vertical rotation. Measured eccentricities were(±60◦) from the fovea in the horizontal meridian and +35 ◦ and -25 ◦ along each of the three vertical meridians. In pigeons, the LOA (astigmatism) on the horizontal meridian increase slightly from the center towards the far periphery but are relatively constant for ±20◦ around the fovea, whereas defocus remains almost constant. Vertical meridian measurements are consistent with the previously reported myopia in the lower visual field. Compared with measurements in human subjects, the overall values of RMS are much lower in the pigeon at all corresponding eccentricities. Off-axis vision is generally dominated by defocus and astigmatism. In pigeons, however, defocus along the horizontal meridian does not change dramatically whereas, along the vertical meridian, the presence of a lower field myopia is confirmed. Astigmatism of the eye for increasing eccentricity (horizontally and vertically) is consistently lower then expected theoretically and when compared with humans. This demonstrates that the visual optics of the pigeon are more fully corrected for peripheral vision than in humans.

Subjects/Keywords: RE Ophthalmology

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APA (6^th Edition):

Garcia Sanchez, Y. (2012). Analysis of retinal image quality for peripheral vision in humans and pigeons (Columba livia). (Doctoral Dissertation). Cardiff University. Retrieved from http://orca.cf.ac.uk/41966/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567444

Chicago Manual of Style (16^th Edition):

Garcia Sanchez, Yaiza. “Analysis of retinal image quality for peripheral vision in humans and pigeons (Columba livia).” 2012. Doctoral Dissertation, Cardiff University. Accessed December 06, 2019. http://orca.cf.ac.uk/41966/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567444.

MLA Handbook (7^th Edition):

Garcia Sanchez, Yaiza. “Analysis of retinal image quality for peripheral vision in humans and pigeons (Columba livia).” 2012. Web. 06 Dec 2019.

Vancouver:

Garcia Sanchez Y. Analysis of retinal image quality for peripheral vision in humans and pigeons (Columba livia). [Internet] [Doctoral dissertation]. Cardiff University; 2012. [cited 2019 Dec 06]. Available from: http://orca.cf.ac.uk/41966/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567444.

Council of Science Editors:

Garcia Sanchez Y. Analysis of retinal image quality for peripheral vision in humans and pigeons (Columba livia). [Doctoral Dissertation]. Cardiff University; 2012. Available from: http://orca.cf.ac.uk/41966/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567444

Cardiff University

9. Mohamad Shahimin, Mizhanim. Development and validation of a digital quantitative orthoptics workstation.

Degree: PhD, 2012, Cardiff University

URL: http://orca.cf.ac.uk/31283/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567310

► The objective of the research is to provide the clinician with a simple system for making quantitative measurements that is comparable to the services of… (more)

▼ The objective of the research is to provide the clinician with a simple system for making quantitative measurements that is comparable to the services of a skilled orthoptist. As many optometrists do not possess the necessary equipment for making such assessments, this technology would significantly enhance their referral capabilities. Reviews of the tests involved and instruments available are detailed in Chapter II and III. Chapter IV presents the various validation experiments carried out on the Tobii X120 eye tracker, concentrating on technical specifications such as, linearity range, optimum measurement distance and setup (with and without chin rest). We also investigated the effect of wearing different types of lens materials and pupil size measurements on the eye tracker system. We established the inter-examiner agreement of cover test measurements on groups of non-strabismic and strabismic subjects. This study, as detailed in Chapter V, involved collaboration with two clinical orthoptists. We found a good inter-examiner agreement for both the non-strabismic and strabismic cover tests. We further investigated the use of the eye tracker in providing more reliable findings for cover test measurements as compared to the conventional cover test (Chapter VI). Finally we extended the investigation to a number of different clinical subjects attending the Bristol Eye Hospital (Chapter VII) in order to evaluate our purpose-developed monocular calibration routine. Performing quantitative eye movement analysis will provide valuable additional information in any clinical investigation of patients with ophthalmological and/or neurological disorders, leading to greater precision in diagnosis. Traditional methods for the evaluation of oculomotor disorders rely on the diagnostic and therapeutic judgements by the examining clinicians and subjective responses from the patient. However, the use of currently available eye movement recording system will provide valuable alternatives for obtaining more objective and quantitative measurements.

Subjects/Keywords: RE Ophthalmology

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APA (6^th Edition):

Mohamad Shahimin, M. (2012). Development and validation of a digital quantitative orthoptics workstation. (Doctoral Dissertation). Cardiff University. Retrieved from http://orca.cf.ac.uk/31283/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567310

Chicago Manual of Style (16^th Edition):

Mohamad Shahimin, Mizhanim. “Development and validation of a digital quantitative orthoptics workstation.” 2012. Doctoral Dissertation, Cardiff University. Accessed December 06, 2019. http://orca.cf.ac.uk/31283/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567310.

MLA Handbook (7^th Edition):

Mohamad Shahimin, Mizhanim. “Development and validation of a digital quantitative orthoptics workstation.” 2012. Web. 06 Dec 2019.

Vancouver:

Mohamad Shahimin M. Development and validation of a digital quantitative orthoptics workstation. [Internet] [Doctoral dissertation]. Cardiff University; 2012. [cited 2019 Dec 06]. Available from: http://orca.cf.ac.uk/31283/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567310.

Council of Science Editors:

Mohamad Shahimin M. Development and validation of a digital quantitative orthoptics workstation. [Doctoral Dissertation]. Cardiff University; 2012. Available from: http://orca.cf.ac.uk/31283/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567310

Cardiff University

10. Dillingham, Christopher Mark. An anatomical and functional characterisation of the avian centrifugal visual system : a feedback pathway from the brain to the retina.

Degree: 2012, Cardiff University

URL: http://orca.cf.ac.uk/41964/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567443

► The centrifugal visual system (CVS) is a feedback pathway of predominantly visual information from the brain to both eyes, but principally to the contralateral retina.… (more)

▼ The centrifugal visual system (CVS) is a feedback pathway of predominantly visual information from the brain to both eyes, but principally to the contralateral retina. The CVS is often considered to be something of a peculiarity, regarded as being specific to birds (Aves). Indeed, so-called ‘higher’ vertebrate species are assumed not to even possess such a centrifugal pathway when, in fact, an efferent projection to the retina has been conclusively demonstrated in all vertebrate groups (including humans). Perhaps this point of view reflects the lack of progress made in the elucidation of function in the bird, the dominant model for CVS research in the 120 years since being first described. In the series of experiments presented here, I have begun to investigate the role of the CVS in the modulation of eye growth. In addition, I have addressed a number of unknowns that exist regarding the midbrain connectivity of the CVS. In a series of four parallel lesion experiments, the centrifugal efferent pathway to the retina was unilaterally disrupted in post hatch chicks, raised under different developmental conditions. Under normal visual conditions but in the absence of centrifugal efferents, eyes contralateral to the lesion developed shorter eyes and moderate, relative hyperopia (long-sightedness). In contrast, under constant light conditions, ipsilateral eyes became significantly shorter than fellow (i.e. contralateral) eyes. Compensation for, and recovery from, plus and minus lens-imposed defocus in contralateral eyes was largely unaffected. Centrifugal efferents emanate from two distinct midbrain populations: the isthmo-optic nucleus (ION) and the surrounding scattered cells within the ectopic area (EA). From experiments using pathway tracing techniques, I have demonstrated that, unlike cells of the ION, EA cells do not receive input from primary visual areas. In addition I present evidence for a possible ‘cross-talk’ pathway between centrifugal cells on either side of the midbrain, and discuss its potential involvement in the normally symmetrical eye growth.

Subjects/Keywords: RE Ophthalmology

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APA (6^th Edition):

Dillingham, C. M. (2012). An anatomical and functional characterisation of the avian centrifugal visual system : a feedback pathway from the brain to the retina. (Doctoral Dissertation). Cardiff University. Retrieved from http://orca.cf.ac.uk/41964/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567443

Chicago Manual of Style (16^th Edition):

Dillingham, Christopher Mark. “An anatomical and functional characterisation of the avian centrifugal visual system : a feedback pathway from the brain to the retina.” 2012. Doctoral Dissertation, Cardiff University. Accessed December 06, 2019. http://orca.cf.ac.uk/41964/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567443.

MLA Handbook (7^th Edition):

Dillingham, Christopher Mark. “An anatomical and functional characterisation of the avian centrifugal visual system : a feedback pathway from the brain to the retina.” 2012. Web. 06 Dec 2019.

Vancouver:

Dillingham CM. An anatomical and functional characterisation of the avian centrifugal visual system : a feedback pathway from the brain to the retina. [Internet] [Doctoral dissertation]. Cardiff University; 2012. [cited 2019 Dec 06]. Available from: http://orca.cf.ac.uk/41964/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567443.

Council of Science Editors:

Dillingham CM. An anatomical and functional characterisation of the avian centrifugal visual system : a feedback pathway from the brain to the retina. [Doctoral Dissertation]. Cardiff University; 2012. Available from: http://orca.cf.ac.uk/41964/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567443

Cardiff University

11. Gaffney, Allannah J. Characterising adaptational dysfunction in age-related macular degeneration.

Degree: 2012, Cardiff University

URL: http://orca.cf.ac.uk/41072/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567427

► Age-related macular degeneration (AMD) is the leading cause of visual impairment in the developed world. The prevalence of this disease will continue to increase over… (more)

▼ Age-related macular degeneration (AMD) is the leading cause of visual impairment in the developed world. The prevalence of this disease will continue to increase over the coming decades as the average age of the global population rises. There is consequently an urgent need to develop tests that are sensitive to early visual dysfunction, in order to identify individuals that have a high risk of developing AMD, to identify patients that would benefit from treatment, to assess the outcomes of that treatment and to evaluate emerging treatment strategies. An emerging body of evidence suggests that dark adaptation is a sensitive biomarker for early AMD. Cone dark adaptation is of particular interest to clinicians, as it can identify patients with early AMD in a relatively short recording period. Consequently, this thesis aimed to optimise psychophysical and electrophysiological techniques for the assessment of cone dark adaptation in early AMD, in order to maximise its diagnostic potential. A range of psychophysical methods were shown to be capable of monitoring the rapid changes in threshold that occur during cone dark adaptation. An optimal psychophysical protocol for the assessment of cone dark adaptation in early AMD was developed based on the results of a systematic evaluation of the effect of stimulus parameters and pre-adapting light intensity on the diagnostic potential of cone dark adaptation in early AMD. When compared to the focal cone ERG photostress test, both techniques were shown to be similarly diagnostic for early AMD. In addition, the time constant of cone recovery was shown to be significantly correlated with age, hence the sensitivity and specificity of cone dark adaptation as a biomarker for early macular disease may be further improved by considering these age-related changes. In conclusion, this thesis has confirmed that cone dark adaptation is a sensitive functional biomarker for early AMD. However, as cross-sectional studies are unable to determine the true diagnostic potential of a biomarker, longitudinal investigations are needed to explore the long-term potential of cone dark adaptation and other visual functions as biomarkers for early AMD.

Subjects/Keywords: RE Ophthalmology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Gaffney, A. J. (2012). Characterising adaptational dysfunction in age-related macular degeneration. (Doctoral Dissertation). Cardiff University. Retrieved from http://orca.cf.ac.uk/41072/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567427

Chicago Manual of Style (16^th Edition):

Gaffney, Allannah J. “Characterising adaptational dysfunction in age-related macular degeneration.” 2012. Doctoral Dissertation, Cardiff University. Accessed December 06, 2019. http://orca.cf.ac.uk/41072/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567427.

MLA Handbook (7^th Edition):

Gaffney, Allannah J. “Characterising adaptational dysfunction in age-related macular degeneration.” 2012. Web. 06 Dec 2019.

Vancouver:

Gaffney AJ. Characterising adaptational dysfunction in age-related macular degeneration. [Internet] [Doctoral dissertation]. Cardiff University; 2012. [cited 2019 Dec 06]. Available from: http://orca.cf.ac.uk/41072/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567427.

Council of Science Editors:

Gaffney AJ. Characterising adaptational dysfunction in age-related macular degeneration. [Doctoral Dissertation]. Cardiff University; 2012. Available from: http://orca.cf.ac.uk/41072/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567427

Cardiff University

12. Mishor, Gabriel. Higher order aberrations and age-related cataract : a pre- and post- operative study.

Degree: 2012, Cardiff University

URL: http://orca.cf.ac.uk/39687/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567412

► The outcome of higher order aberrations (HOAs) prior to, and following, age-related cataract extraction and intra-ocular lens (IOL) implantation was explored using placido disc skiaoscopy… (more)

▼ The outcome of higher order aberrations (HOAs) prior to, and following, age-related cataract extraction and intra-ocular lens (IOL) implantation was explored using placido disc skiaoscopy aberrometry. Ninety-nine individuals (median age 73.0, IQR 67.0, 80.5) underwent comprehensive ophthalmic examination including contrast sensitivity, endothelial cell imaging and aberrometry (Nidek OPD ARK-10000) at approximately 4 weeks pre-operatively (median 3.9, IQR 2.9, 4.8) 10 weeks (median 7.1, IQR 5.64, 11.71) (67 individuals) and 80 weeks (median 85.1, IQR 80.0, 89.6) (41 individuals) post-operatively. Linear relationships between thirteen demographical, functional and structural variables and each of three components, Total (TC), Corneal (CC) and Internal (IC), for each of eight HOAs, were separately explored, using Analysis of Variance, for each examination and for the pre- and post-operative differences, respectively. The TC and IC of all HOAs decreased post-operatively (p≤68%). Preoperatively, the TC and IC of the Total HOA decreased as the spherical equivalent (SE) became less negative (both p<0.001, R2=0.56 and 0.53). Both components of the Total HOA also decreased as the difference in SE between baseline and each follow-up became less negative (all p≤0.008, R2=0.45-0.61); the magnitude of the reduction varied between IOL type (p≤0.008). The IC of the Tilt, T.Sph and HiAstig HOAs increased with increase in severity of posterior subcapsular (p=0.018), of cortical (p=0.013) and of combined nuclear colour and cortical cataract (p=0.003), respectively. The relationship between cataract type and severity and reduction in post-operative HOA was not statistically significant at either follow-up examination. Slight associations, presumably due to post-operative corneal oedema, were present between increase in CCs of five HOAs and decreasing endothelial cell density at the first follow-up, only, (all p≤0.030, R2=0.09-0.14). Pre-operative TCs and ICs were larger, respectively, than those of 22 individuals with ‘less severe’ cataract and post-operatively than those of 49 individuals with clear media, obtained from retrospective data.

Subjects/Keywords: RE Ophthalmology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Mishor, G. (2012). Higher order aberrations and age-related cataract : a pre- and post- operative study. (Doctoral Dissertation). Cardiff University. Retrieved from http://orca.cf.ac.uk/39687/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567412

Chicago Manual of Style (16^th Edition):

Mishor, Gabriel. “Higher order aberrations and age-related cataract : a pre- and post- operative study.” 2012. Doctoral Dissertation, Cardiff University. Accessed December 06, 2019. http://orca.cf.ac.uk/39687/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567412.

MLA Handbook (7^th Edition):

Mishor, Gabriel. “Higher order aberrations and age-related cataract : a pre- and post- operative study.” 2012. Web. 06 Dec 2019.

Vancouver:

Mishor G. Higher order aberrations and age-related cataract : a pre- and post- operative study. [Internet] [Doctoral dissertation]. Cardiff University; 2012. [cited 2019 Dec 06]. Available from: http://orca.cf.ac.uk/39687/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567412.

Council of Science Editors:

Mishor G. Higher order aberrations and age-related cataract : a pre- and post- operative study. [Doctoral Dissertation]. Cardiff University; 2012. Available from: http://orca.cf.ac.uk/39687/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567412

Cardiff University

13. Luraas, Knut. Clinical aspects of Critical Flicker Fusion perimetry : an in-depth analysis.

Degree: 2012, Cardiff University

URL: http://orca.cf.ac.uk/39684/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567411

► The thesis evaluated, in three studies, the clinical potential of Critical Flicker Fusion perimetry (CFFP) undertaken using the Octopus 311 perimeter. The influence of the… (more)

Subjects/Keywords: RE Ophthalmology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Luraas, K. (2012). Clinical aspects of Critical Flicker Fusion perimetry : an in-depth analysis. (Doctoral Dissertation). Cardiff University. Retrieved from http://orca.cf.ac.uk/39684/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567411

Chicago Manual of Style (16^th Edition):

Luraas, Knut. “Clinical aspects of Critical Flicker Fusion perimetry : an in-depth analysis.” 2012. Doctoral Dissertation, Cardiff University. Accessed December 06, 2019. http://orca.cf.ac.uk/39684/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567411.

MLA Handbook (7^th Edition):

Luraas, Knut. “Clinical aspects of Critical Flicker Fusion perimetry : an in-depth analysis.” 2012. Web. 06 Dec 2019.

Vancouver:

Luraas K. Clinical aspects of Critical Flicker Fusion perimetry : an in-depth analysis. [Internet] [Doctoral dissertation]. Cardiff University; 2012. [cited 2019 Dec 06]. Available from: http://orca.cf.ac.uk/39684/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567411.

Council of Science Editors:

Luraas K. Clinical aspects of Critical Flicker Fusion perimetry : an in-depth analysis. [Doctoral Dissertation]. Cardiff University; 2012. Available from: http://orca.cf.ac.uk/39684/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567411

Cardiff University

14. Robinson, David. Low-level night-time light therapy for age-related macular degeneration.

Degree: PhD, 2017, Cardiff University

URL: http://orca.cf.ac.uk/108368/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732286

► Age-related macular degeneration (AMD) is the leading cause of visual impairment in the developed world (Wong et al., 2014). The exact causes of AMD are… (more)

Subjects/Keywords: RE Ophthalmology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Robinson, D. (2017). Low-level night-time light therapy for age-related macular degeneration. (Doctoral Dissertation). Cardiff University. Retrieved from http://orca.cf.ac.uk/108368/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732286

Chicago Manual of Style (16^th Edition):

Robinson, David. “Low-level night-time light therapy for age-related macular degeneration.” 2017. Doctoral Dissertation, Cardiff University. Accessed December 06, 2019. http://orca.cf.ac.uk/108368/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732286.

MLA Handbook (7^th Edition):

Robinson, David. “Low-level night-time light therapy for age-related macular degeneration.” 2017. Web. 06 Dec 2019.

Vancouver:

Robinson D. Low-level night-time light therapy for age-related macular degeneration. [Internet] [Doctoral dissertation]. Cardiff University; 2017. [cited 2019 Dec 06]. Available from: http://orca.cf.ac.uk/108368/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732286.

Council of Science Editors:

Robinson D. Low-level night-time light therapy for age-related macular degeneration. [Doctoral Dissertation]. Cardiff University; 2017. Available from: http://orca.cf.ac.uk/108368/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732286

Cardiff University

15. Terry, Louise. An in vivo investigation of choroidal vasculature in age-related macular degeneration.

Degree: PhD, 2017, Cardiff University

URL: http://orca.cf.ac.uk/107459/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732243

► Age-related macular degeneration (AMD) is the leading cause of visual impairment in the developed world. Whilst the pathogenesis is complex and not fully understood, changes… (more)

▼ Age-related macular degeneration (AMD) is the leading cause of visual impairment in the developed world. Whilst the pathogenesis is complex and not fully understood, changes to the choroidal vasculature in AMD have been demonstrated using histology. Advances in imaging technology, particularly long-wavelength optical coherence tomography (OCT), allow in vivo visualisation and investigation of this structure. The aim of this work is to determine whether changes to the choroidal vasculature are detectable in AMD using in vivo imaging. This was achieved through the evaluation of parameters for quantifying the structure, and the application of a machine learning approach to automated disease severity classification, based on choroidal appearance. Participants with early AMD (n=25), neovascular AMD (nAMD; n=25), and healthy controls (n=25) underwent imaging with a non-commercial long-wavelength (λc=1040 nm) OCT device. Subfoveal choroidal thickness, choroidal area, and luminal area were significantly lower in the nAMD group than the healthy and early AMD groups, whilst vessel ratio was significantly greater (P < 0.05 in all cases). There was no significant difference in visible vessel diameter, choroidal vascularity index, luminal area ratio, or luminal perimeter ratio between the groups. No significant differences were found between the healthy and early AMD groups for any of the eight vascular parameters assessed. Classification of the disease groups based on choroidal OCT images was demonstrated using machine learning techniques. Textural features within the images were extracted using Gabor filters, and K-nearest neighbour, support vector machine, and random forest classifiers were assessed for this classification task. Textural changes were most pronounced in late-stage disease, although attribution to pathology or pharmacological intervention (anti-VEGF treatment) was not possible. Changes were also discernible in the early AMD group, suggesting sensitivity of this approach to detecting vascular involvement in early disease. In conclusion, structural changes to the choroidal vasculature in AMD are detectable in vivo using OCT imaging, demonstrated with both manual and automated analysis techniques. Whilst changes were most prominent in late-stage disease, subtle structural changes in early AMD were identified with texture analysis, warranting further investigation to improve our understanding of choroidal involvement in the pathogenesis of early AMD.

Subjects/Keywords: RE Ophthalmology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Terry, L. (2017). An in vivo investigation of choroidal vasculature in age-related macular degeneration. (Doctoral Dissertation). Cardiff University. Retrieved from http://orca.cf.ac.uk/107459/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732243

Chicago Manual of Style (16^th Edition):

Terry, Louise. “An in vivo investigation of choroidal vasculature in age-related macular degeneration.” 2017. Doctoral Dissertation, Cardiff University. Accessed December 06, 2019. http://orca.cf.ac.uk/107459/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732243.

MLA Handbook (7^th Edition):

Terry, Louise. “An in vivo investigation of choroidal vasculature in age-related macular degeneration.” 2017. Web. 06 Dec 2019.

Vancouver:

Terry L. An in vivo investigation of choroidal vasculature in age-related macular degeneration. [Internet] [Doctoral dissertation]. Cardiff University; 2017. [cited 2019 Dec 06]. Available from: http://orca.cf.ac.uk/107459/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732243.

Council of Science Editors:

Terry L. An in vivo investigation of choroidal vasculature in age-related macular degeneration. [Doctoral Dissertation]. Cardiff University; 2017. Available from: http://orca.cf.ac.uk/107459/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732243

Cardiff University

16. Van Tilborg, Maria. The role of primary healthcare in the management of work-related DED in the Netherlands.

Degree: PhD, 2017, Cardiff University

URL: http://orca.cf.ac.uk/107038/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732229

► Dry eye disease (DED), and especially work-related dry eye, has an increasing incidence, and is expected to become a significant public health problem, with the… (more)

Subjects/Keywords: RE Ophthalmology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Van Tilborg, M. (2017). The role of primary healthcare in the management of work-related DED in the Netherlands. (Doctoral Dissertation). Cardiff University. Retrieved from http://orca.cf.ac.uk/107038/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732229

Chicago Manual of Style (16^th Edition):

Van Tilborg, Maria. “The role of primary healthcare in the management of work-related DED in the Netherlands.” 2017. Doctoral Dissertation, Cardiff University. Accessed December 06, 2019. http://orca.cf.ac.uk/107038/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732229.

MLA Handbook (7^th Edition):

Van Tilborg, Maria. “The role of primary healthcare in the management of work-related DED in the Netherlands.” 2017. Web. 06 Dec 2019.

Vancouver:

Van Tilborg M. The role of primary healthcare in the management of work-related DED in the Netherlands. [Internet] [Doctoral dissertation]. Cardiff University; 2017. [cited 2019 Dec 06]. Available from: http://orca.cf.ac.uk/107038/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732229.

Council of Science Editors:

Van Tilborg M. The role of primary healthcare in the management of work-related DED in the Netherlands. [Doctoral Dissertation]. Cardiff University; 2017. Available from: http://orca.cf.ac.uk/107038/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732229

Cardiff University

17. Chandrinos, Aristeidis. Aspects of a perimetric learning index.

Degree: PhD, 2017, Cardiff University

URL: http://orca.cf.ac.uk/107979/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732271

► The purpose of this thesis was to develop further the Learning Index in perimetry and examine how it performs in different groups, with different algorithms… (more)

Subjects/Keywords: RE Ophthalmology

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APA (6^th Edition):

Chandrinos, A. (2017). Aspects of a perimetric learning index. (Doctoral Dissertation). Cardiff University. Retrieved from http://orca.cf.ac.uk/107979/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732271

Chicago Manual of Style (16^th Edition):

Chandrinos, Aristeidis. “Aspects of a perimetric learning index.” 2017. Doctoral Dissertation, Cardiff University. Accessed December 06, 2019. http://orca.cf.ac.uk/107979/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732271.

MLA Handbook (7^th Edition):

Chandrinos, Aristeidis. “Aspects of a perimetric learning index.” 2017. Web. 06 Dec 2019.

Vancouver:

Chandrinos A. Aspects of a perimetric learning index. [Internet] [Doctoral dissertation]. Cardiff University; 2017. [cited 2019 Dec 06]. Available from: http://orca.cf.ac.uk/107979/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732271.

Council of Science Editors:

Chandrinos A. Aspects of a perimetric learning index. [Doctoral Dissertation]. Cardiff University; 2017. Available from: http://orca.cf.ac.uk/107979/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.732271

Cardiff University

18. Robinson, David Grant. Low-level night-time light therapy for age-related macular degeneration.

Degree: PhD, 2017, Cardiff University

URL: http://orca.cf.ac.uk/108368/

► Age-related macular degeneration (AMD) is the leading cause of visual impairment in the developed world (Wong et al., 2014). The exact causes of AMD are… (more)

Subjects/Keywords: RE Ophthalmology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Robinson, D. G. (2017). Low-level night-time light therapy for age-related macular degeneration. (Doctoral Dissertation). Cardiff University. Retrieved from http://orca.cf.ac.uk/108368/

Chicago Manual of Style (16^th Edition):

Robinson, David Grant. “Low-level night-time light therapy for age-related macular degeneration.” 2017. Doctoral Dissertation, Cardiff University. Accessed December 06, 2019. http://orca.cf.ac.uk/108368/.

MLA Handbook (7^th Edition):

Robinson, David Grant. “Low-level night-time light therapy for age-related macular degeneration.” 2017. Web. 06 Dec 2019.

Vancouver:

Robinson DG. Low-level night-time light therapy for age-related macular degeneration. [Internet] [Doctoral dissertation]. Cardiff University; 2017. [cited 2019 Dec 06]. Available from: http://orca.cf.ac.uk/108368/.

Council of Science Editors:

Robinson DG. Low-level night-time light therapy for age-related macular degeneration. [Doctoral Dissertation]. Cardiff University; 2017. Available from: http://orca.cf.ac.uk/108368/

Cardiff University

19. Cassels, Nicola. Quality-of-life and clinical outcomes in age-related macular degeneration.

Degree: PhD, 2017, Cardiff University

URL: http://orca.cf.ac.uk/109189/

► Age-related macular degeneration (AMD) is of increasing concern given the ageing population, and the associated economic and social burdens. Vision-related quality-of-life (QoL) is arguably one… (more)

Subjects/Keywords: RE Ophthalmology

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APA (6^th Edition):

Cassels, N. (2017). Quality-of-life and clinical outcomes in age-related macular degeneration. (Doctoral Dissertation). Cardiff University. Retrieved from http://orca.cf.ac.uk/109189/

Chicago Manual of Style (16^th Edition):

Cassels, Nicola. “Quality-of-life and clinical outcomes in age-related macular degeneration.” 2017. Doctoral Dissertation, Cardiff University. Accessed December 06, 2019. http://orca.cf.ac.uk/109189/.

MLA Handbook (7^th Edition):

Cassels, Nicola. “Quality-of-life and clinical outcomes in age-related macular degeneration.” 2017. Web. 06 Dec 2019.

Vancouver:

Cassels N. Quality-of-life and clinical outcomes in age-related macular degeneration. [Internet] [Doctoral dissertation]. Cardiff University; 2017. [cited 2019 Dec 06]. Available from: http://orca.cf.ac.uk/109189/.

Council of Science Editors:

Cassels N. Quality-of-life and clinical outcomes in age-related macular degeneration. [Doctoral Dissertation]. Cardiff University; 2017. Available from: http://orca.cf.ac.uk/109189/

Cardiff University

20. Beirne, Kathy. Exploring the potential of red light therapy as a treatment for retinal ganglion cell degeneration.

Degree: PhD, 2017, Cardiff University

URL: http://orca.cf.ac.uk/109384/

► Mutations in OPA1 are the leading cause of autosomal dominant optic atrophy, a disease in which a progressive loss of retinal ganglion cells (RGCs) leads… (more)

Subjects/Keywords: RE Ophthalmology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Beirne, K. (2017). Exploring the potential of red light therapy as a treatment for retinal ganglion cell degeneration. (Doctoral Dissertation). Cardiff University. Retrieved from http://orca.cf.ac.uk/109384/

Chicago Manual of Style (16^th Edition):

Beirne, Kathy. “Exploring the potential of red light therapy as a treatment for retinal ganglion cell degeneration.” 2017. Doctoral Dissertation, Cardiff University. Accessed December 06, 2019. http://orca.cf.ac.uk/109384/.

MLA Handbook (7^th Edition):

Beirne, Kathy. “Exploring the potential of red light therapy as a treatment for retinal ganglion cell degeneration.” 2017. Web. 06 Dec 2019.

Vancouver:

Beirne K. Exploring the potential of red light therapy as a treatment for retinal ganglion cell degeneration. [Internet] [Doctoral dissertation]. Cardiff University; 2017. [cited 2019 Dec 06]. Available from: http://orca.cf.ac.uk/109384/.

Council of Science Editors:

Beirne K. Exploring the potential of red light therapy as a treatment for retinal ganglion cell degeneration. [Doctoral Dissertation]. Cardiff University; 2017. Available from: http://orca.cf.ac.uk/109384/

University of Birmingham

21. Denniston, Alastair K O. Regulation of Dendritic cell function by the ocular microenvironment.

Degree: d_ph, College of Medical & Dental Sciences, 2010, University of Birmingham

URL: http://etheses.bham.ac.uk//id/eprint/932/

► The ocular microenvironment is immunosuppressive in animal models of antigen presenting cell function. My hypothesis was that in humans the normal ocular microenvironment maintains an… (more)

Subjects/Keywords: RE Ophthalmology

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APA (6^th Edition):

Denniston, A. K. O. (2010). Regulation of Dendritic cell function by the ocular microenvironment. (Thesis). University of Birmingham. Retrieved from http://etheses.bham.ac.uk//id/eprint/932/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Denniston, Alastair K O. “Regulation of Dendritic cell function by the ocular microenvironment.” 2010. Thesis, University of Birmingham. Accessed December 06, 2019. http://etheses.bham.ac.uk//id/eprint/932/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Denniston, Alastair K O. “Regulation of Dendritic cell function by the ocular microenvironment.” 2010. Web. 06 Dec 2019.

Vancouver:

Denniston AKO. Regulation of Dendritic cell function by the ocular microenvironment. [Internet] [Thesis]. University of Birmingham; 2010. [cited 2019 Dec 06]. Available from: http://etheses.bham.ac.uk//id/eprint/932/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Denniston AKO. Regulation of Dendritic cell function by the ocular microenvironment. [Thesis]. University of Birmingham; 2010. Available from: http://etheses.bham.ac.uk//id/eprint/932/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Birmingham

22. Edmunds, Matthew Ross. Investigation of candidate biomarkers in Graves' disease and thyroid-associated ophthalmopathy.

Degree: d_ph, College of Medical & Dental Sciences, 2016, University of Birmingham

URL: http://etheses.bham.ac.uk//id/eprint/6065/

► Thyroid-Associated Ophthalmopathy (TAO) is a debilitating inflammatory condition of the orbit occurring in 30-50% of Graves' Disease (GD) patients. It is not currently possible to… (more)

Subjects/Keywords: RE Ophthalmology

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APA (6^th Edition):

Edmunds, M. R. (2016). Investigation of candidate biomarkers in Graves' disease and thyroid-associated ophthalmopathy. (Thesis). University of Birmingham. Retrieved from http://etheses.bham.ac.uk//id/eprint/6065/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Edmunds, Matthew Ross. “Investigation of candidate biomarkers in Graves' disease and thyroid-associated ophthalmopathy.” 2016. Thesis, University of Birmingham. Accessed December 06, 2019. http://etheses.bham.ac.uk//id/eprint/6065/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Edmunds, Matthew Ross. “Investigation of candidate biomarkers in Graves' disease and thyroid-associated ophthalmopathy.” 2016. Web. 06 Dec 2019.

Vancouver:

Edmunds MR. Investigation of candidate biomarkers in Graves' disease and thyroid-associated ophthalmopathy. [Internet] [Thesis]. University of Birmingham; 2016. [cited 2019 Dec 06]. Available from: http://etheses.bham.ac.uk//id/eprint/6065/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Edmunds MR. Investigation of candidate biomarkers in Graves' disease and thyroid-associated ophthalmopathy. [Thesis]. University of Birmingham; 2016. Available from: http://etheses.bham.ac.uk//id/eprint/6065/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Birmingham

23. Barry, Robert John. Investigating the immunoregulatory role of betaglycan.

Degree: d_ph, College of Medical & Dental Sciences, 2016, University of Birmingham

URL: http://etheses.bham.ac.uk//id/eprint/6432/

► Betaglycan, also known as TGFβRIII, is a component of the TGFβ receptor, being thought to act as a co-factor in signal transduction. It has proven… (more)

Subjects/Keywords: RE Ophthalmology

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APA (6^th Edition):

Barry, R. J. (2016). Investigating the immunoregulatory role of betaglycan. (Thesis). University of Birmingham. Retrieved from http://etheses.bham.ac.uk//id/eprint/6432/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Barry, Robert John. “Investigating the immunoregulatory role of betaglycan.” 2016. Thesis, University of Birmingham. Accessed December 06, 2019. http://etheses.bham.ac.uk//id/eprint/6432/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Barry, Robert John. “Investigating the immunoregulatory role of betaglycan.” 2016. Web. 06 Dec 2019.

Vancouver:

Barry RJ. Investigating the immunoregulatory role of betaglycan. [Internet] [Thesis]. University of Birmingham; 2016. [cited 2019 Dec 06]. Available from: http://etheses.bham.ac.uk//id/eprint/6432/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Barry RJ. Investigating the immunoregulatory role of betaglycan. [Thesis]. University of Birmingham; 2016. Available from: http://etheses.bham.ac.uk//id/eprint/6432/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Cardiff University

24. Cassels, Nicola. Quality-of-life and clinical outcomes in age-related macular degeneration.

Degree: PhD, 2017, Cardiff University

URL: http://orca.cf.ac.uk/109189/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.738351

► Age-related macular degeneration (AMD) is of increasing concern given the ageing population, and the associated economic and social burdens. Vision-related quality-of-life (QoL) is arguably one… (more)

Subjects/Keywords: RE Ophthalmology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Cassels, N. (2017). Quality-of-life and clinical outcomes in age-related macular degeneration. (Doctoral Dissertation). Cardiff University. Retrieved from http://orca.cf.ac.uk/109189/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.738351

Chicago Manual of Style (16^th Edition):

Cassels, Nicola. “Quality-of-life and clinical outcomes in age-related macular degeneration.” 2017. Doctoral Dissertation, Cardiff University. Accessed December 06, 2019. http://orca.cf.ac.uk/109189/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.738351.

MLA Handbook (7^th Edition):

Cassels, Nicola. “Quality-of-life and clinical outcomes in age-related macular degeneration.” 2017. Web. 06 Dec 2019.

Vancouver:

Cassels N. Quality-of-life and clinical outcomes in age-related macular degeneration. [Internet] [Doctoral dissertation]. Cardiff University; 2017. [cited 2019 Dec 06]. Available from: http://orca.cf.ac.uk/109189/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.738351.

Council of Science Editors:

Cassels N. Quality-of-life and clinical outcomes in age-related macular degeneration. [Doctoral Dissertation]. Cardiff University; 2017. Available from: http://orca.cf.ac.uk/109189/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.738351

University of Glasgow

25. McMenamin, Paul G. The biology of immune cells in the eye: Implications for development, health and disease.

Degree: 2009, University of Glasgow

URL: http://theses.gla.ac.uk/3187/

► The work presented in this thesis is a collection of papers from research spanning over 25 years. The research commenced whilst the candidate was employed… (more)

▼ The work presented in this thesis is a collection of papers from research spanning over 25 years. The research commenced whilst the candidate was employed in the Tennent Institute of Ophthalmology and later the Department of Anatomy at the University of Glasgow and continued in the School of Anatomy & Human Biology, The University of Western Australia. The research focuses on the biology of immune cells, primarily dendritic cells (DC), macrophages and mast cells, in the context of various components of the eye, including the aqueous outflow pathways, iris, cornea, ciliary body, choroid and retina, and the supporting tissues (lids and conjunctiva). The studies are broad in the sense that they deal with the role of these cells in development (such as removing the vascular networks around the developing lens), their normal homeostasis and function (distribution, phenotype, turnover and functional activity) and their role in models of a number of eye diseases. The findings are important in understanding the pathogenesis of diseases including bacterial keratitis, anterior uveitis, autoimmune uveoretinitis (endogenous posterior uveitis), toxoplasmic retinochoroiditis, age-related macular degeneration and ocular allergic responses, namely any ocular disease with an immune-mediated pathology. Many of the findings in the enclosed papers were firsts in the field and have shaped our understanding of ocular inflammatory disease. In part the success of some these studies was due to the novel method of performing immunostaining on tissue wholemounts dissected from small rodent eyes. These preparations provided unique ‘plan’ views of the complex networks of DCs and macrophages in the iris and choroid which previously had not been appreciated. In addition, the wholemount approach used in the characterisation and study of immune cells in delicate eye tissues, were applied to related studies of the meninges and choroid plexus of the brain. These studies were amongst the first to fully characterise distinct DC and macrophage networks in the pia, arachnoid, dura and choroid plexus. The research presented in the more recent publications have utilised a range of transgenic, knock-out, congenic and chimeric mouse models to elucidate the function of immune cells in the eye.

Subjects/Keywords: RE Ophthalmology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

McMenamin, P. G. (2009). The biology of immune cells in the eye: Implications for development, health and disease. (Thesis). University of Glasgow. Retrieved from http://theses.gla.ac.uk/3187/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

McMenamin, Paul G. “The biology of immune cells in the eye: Implications for development, health and disease.” 2009. Thesis, University of Glasgow. Accessed December 06, 2019. http://theses.gla.ac.uk/3187/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

McMenamin, Paul G. “The biology of immune cells in the eye: Implications for development, health and disease.” 2009. Web. 06 Dec 2019.

Vancouver:

McMenamin PG. The biology of immune cells in the eye: Implications for development, health and disease. [Internet] [Thesis]. University of Glasgow; 2009. [cited 2019 Dec 06]. Available from: http://theses.gla.ac.uk/3187/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

McMenamin PG. The biology of immune cells in the eye: Implications for development, health and disease. [Thesis]. University of Glasgow; 2009. Available from: http://theses.gla.ac.uk/3187/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Warwick

26. Al-Athamneh, Nidal. Communicating risk information about diabetic retinopathy to people with type 2 diabetes.

Degree: PhD, 2018, University of Warwick

URL: http://wrap.warwick.ac.uk/103283/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.752492

► A two-stage qualitative research strategy using semi-structured interviews was conducted with a convenience sample of 45 participants who lives with type 2 diabetes. In Stage… (more)

▼ A two-stage qualitative research strategy using semi-structured interviews was conducted with a convenience sample of 45 participants who lives with type 2 diabetes. In Stage One of the research, a qualitative study was conducted using semi-structured interviews with a purposive sample of 25 participants. Of these, 20 participants were diagnosed with type 2 diabetes, two participants were primary care physicians, two were ophthalmologists, and one was a retinal screener. People with diabetes were purposely recruited to fall into four groups with different grades of diabetic retinopathy. The aim of Stage One was to explore how people with type 2 diabetes perceive diabetic retinopathy risk, their understanding of risk information, and to appraise existing risk communication tools that have been used in other clinical settings. The data from Stage One was analysed and used to develop a risk communication tool designed to provide risk information about diabetic retinopathy and diabetic screening results to people with type 2 diabetes, which was then used in Stage Two. In Stage Two of this research, a total of twenty people with type 2 diabetes were recruited. Participants were divided into two groups based on their grade of diabetic retinopathy. Group one: 10 participants with no diabetic retinopathy (R0); Group two: 10 participants who had background diabetic retinopathy (R1). The aim of Stage Two was to i) appraise a newly developed risk communication tool that was developed to communicate risk information about diabetic retinopathy to people with type 2 diabetes, ii) to explore the influence of the new developed risk tool on risk perception and on diabetes self-care management, and iii) to establish a method(s) by which risk information about diabetic retinopathy can be effectively communicated to people with type 2 diabetes. All interviews were audio recorded and transcribed using a digital recording machine. Data was analysed using constructivist grounded theory approach.

Subjects/Keywords: RE Ophthalmology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Al-Athamneh, N. (2018). Communicating risk information about diabetic retinopathy to people with type 2 diabetes. (Doctoral Dissertation). University of Warwick. Retrieved from http://wrap.warwick.ac.uk/103283/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.752492

Chicago Manual of Style (16^th Edition):

Al-Athamneh, Nidal. “Communicating risk information about diabetic retinopathy to people with type 2 diabetes.” 2018. Doctoral Dissertation, University of Warwick. Accessed December 06, 2019. http://wrap.warwick.ac.uk/103283/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.752492.

MLA Handbook (7^th Edition):

Al-Athamneh, Nidal. “Communicating risk information about diabetic retinopathy to people with type 2 diabetes.” 2018. Web. 06 Dec 2019.

Vancouver:

Al-Athamneh N. Communicating risk information about diabetic retinopathy to people with type 2 diabetes. [Internet] [Doctoral dissertation]. University of Warwick; 2018. [cited 2019 Dec 06]. Available from: http://wrap.warwick.ac.uk/103283/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.752492.

Council of Science Editors:

Al-Athamneh N. Communicating risk information about diabetic retinopathy to people with type 2 diabetes. [Doctoral Dissertation]. University of Warwick; 2018. Available from: http://wrap.warwick.ac.uk/103283/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.752492

Cardiff University

27. Aldahlawi, Nada. Investigations into the potential effectiveness of new and existing corneal cross-linking therapies.

Degree: PhD, 2018, Cardiff University

URL: http://orca.cf.ac.uk/112180/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.753547

► The studies comprising this thesis were conducted to examine the potential of a range of cross-linking therapies; in particular, to investigate the effect of a… (more)

▼ The studies comprising this thesis were conducted to examine the potential of a range of cross-linking therapies; in particular, to investigate the effect of a novel cross-linking therapy (involving a bacteriochlorophyll derivative and near-infra red illumination (WST-D/NIR)) on the structure of the cornea, and to develop a trans-epithelial riboflavin/Ultraviolet-A (UVA) corneal cross-linking protocol that was equally effective to that of the standard protocol (SCXL), without the need for epithelium removal. A number of laboratory techniques were used to investigate changes in the structure of the cornea and its biochemical and biomechanical properties following cross-linking. X-ray scattering and electron microscopy data provided evidence that treatment with WST-D/NIR resulted in no change in corneal collagen organisation and confirmed its potential as an alternative to riboflavin/UVA cross-linking for stiffening diseased or surgically weakened corneas. Enzyme digestion studies and strip extensometry were performed to compare the effectiveness of newly developed riboflavin/UVA protocols to that of the SCXL protocol in terms of their ability to increase the enzymatic resistance and stiffness of the cornea. The studies indicated that the intensity and distribution of cross-links formed within the cornea vary with different protocols, and that the outcome of trans-epithelial riboflavin/UVA cross-linking may be significantly enhanced through the use of higher concentrations of riboflavin, a longer duration of iontophoresis and the use of pulsed and higher energy dose UVA. Although the precise amount of CXL required to prevent the disease progression is still unidentified, the full stromal depth of CXL post SCXL treatment might not be needed, therefore, modified trans-epithelial protocols identified in this thesis may be sufficient to prevent disease progression. Further clinical studies, especially randomized prospective trials, are, however, required to confirm the encouraging results of these modified procedures.

Subjects/Keywords: RE Ophthalmology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Aldahlawi, N. (2018). Investigations into the potential effectiveness of new and existing corneal cross-linking therapies. (Doctoral Dissertation). Cardiff University. Retrieved from http://orca.cf.ac.uk/112180/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.753547

Chicago Manual of Style (16^th Edition):

Aldahlawi, Nada. “Investigations into the potential effectiveness of new and existing corneal cross-linking therapies.” 2018. Doctoral Dissertation, Cardiff University. Accessed December 06, 2019. http://orca.cf.ac.uk/112180/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.753547.

MLA Handbook (7^th Edition):

Aldahlawi, Nada. “Investigations into the potential effectiveness of new and existing corneal cross-linking therapies.” 2018. Web. 06 Dec 2019.

Vancouver:

Aldahlawi N. Investigations into the potential effectiveness of new and existing corneal cross-linking therapies. [Internet] [Doctoral dissertation]. Cardiff University; 2018. [cited 2019 Dec 06]. Available from: http://orca.cf.ac.uk/112180/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.753547.

Council of Science Editors:

Aldahlawi N. Investigations into the potential effectiveness of new and existing corneal cross-linking therapies. [Doctoral Dissertation]. Cardiff University; 2018. Available from: http://orca.cf.ac.uk/112180/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.753547

28. Hristova, Elitsa. Microstructural Macular Changes in Patients with Socially Significant Retinal Diseases /// Микроструктурни характеристики на промените в макулата при заболявания на ретината със социално значение.

Degree: phd, Department of Physiotherapy, Rehabilitation, Thalassotherapy and Occupational Diseases, 2016, Medical University of Varna

URL: http://eprints.mu-varna.bg/235/

► [EN] The main purpose of this study is to perform an assessment of the microstructural macular changes in patients with social retinal diseases. To compare… (more)

▼ [EN] The main purpose of this study is to perform an assessment of the microstructural macular changes in patients with social retinal diseases. To compare the diagnostic means of optical coherence tomography (OCT) and fluorescein angiography (FA) in this patients. The study included 417 eyes of 293 subjects who were divided into two large groups. Group I included 200 healthy eyes of 102 subjects, mean age 44,7±18,5 years (16-82 years); 54 women, 48 men, without systemic or ocular disease, untreated surgically and/or medically, BCVA ? 1.0. All patients in this group were examined by 3D OCT-2000Topcon. The group with pathological retinal changes was divided into following subgroups: group II А – 60 eyes of 50 subjects with dry age-related macular degeneration (AMD); group II B - 55 eyes of 50 subjects with wet AMD; group III – 51 eyes of 50 subjects with retinal vein occlusion (RVO) (42 eyes with branch RVO and 9 eyes with central RVO); group IV – 51 eyes of 41 subjects with central serous chorioretinopathy (CSC). Microstructural images of all subjects were obtained using OCT. With the assistance of optical coherence tomography was measured also macular thickness and volume. The group with pathological retinal changes was examined also with fluorescein angiography (FA). The results these two methods of examination were analyzed qualitatively and quantitatively. There was negative statistically significant correlation between macular retinal thickness and volume in healthy subjects group and age. There was no statistically significant correlation between these parameters and gender. The macular thickness was maximal at age between 30 and 50 years and decrease with age. Macular thickness decreasing was with 0.150 µm per year. There were statistically significant lower macular thickness in inner 3mm ETDRS ring, mean retinal thickness, central point thickness and volume in patients with dry AMD compared to healthy subjects. Statistically significant higher macular thickness in fovea and central point thickness has group with wet AMD compared to healthy subjects. There was statistically significant difference between dry and wet AMD group for fovea, nasal parafoveally and perifoveal zones, central point thickness and volume. There was statistically significant higher macular thickness for all ETDRS zones in patients with BRVO compared to healthy subjects. Similar were results for patients with CRVO compared to healthy subjects except central point thickness. There was statistically significant difference between BRVO and CRVO group but only for inferior parafoveal zone. There were statistically significant higher macular thickness, central point thickness and volume and all ETDRS zones, except inferior and temporal parafoveal zones in patients with CSC compared to group I. There was moderate statistically significant negative correlation between visual acuity in group with dry AMD and OCT changes in IS/OS junction and ELM. The presence of intraretinal cysts in inner retinal layers affects visual acuity in…

Subjects/Keywords: RE Ophthalmology

Record Details Similar Records Cite « Share

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hristova, E. (2016). Microstructural Macular Changes in Patients with Socially Significant Retinal Diseases /// Микроструктурни характеристики на промените в макулата при заболявания на ретината със социално значение. (Doctoral Dissertation). Medical University of Varna. Retrieved from http://eprints.mu-varna.bg/235/

Chicago Manual of Style (16^th Edition):

Hristova, Elitsa. “Microstructural Macular Changes in Patients with Socially Significant Retinal Diseases /// Микроструктурни характеристики на промените в макулата при заболявания на ретината със социално значение.” 2016. Doctoral Dissertation, Medical University of Varna. Accessed December 06, 2019. http://eprints.mu-varna.bg/235/.

MLA Handbook (7^th Edition):

Hristova, Elitsa. “Microstructural Macular Changes in Patients with Socially Significant Retinal Diseases /// Микроструктурни характеристики на промените в макулата при заболявания на ретината със социално значение.” 2016. Web. 06 Dec 2019.

Vancouver:

Hristova E. Microstructural Macular Changes in Patients with Socially Significant Retinal Diseases /// Микроструктурни характеристики на промените в макулата при заболявания на ретината със социално значение. [Internet] [Doctoral dissertation]. Medical University of Varna; 2016. [cited 2019 Dec 06]. Available from: http://eprints.mu-varna.bg/235/.

Council of Science Editors:

Hristova E. Microstructural Macular Changes in Patients with Socially Significant Retinal Diseases /// Микроструктурни характеристики на промените в макулата при заболявания на ретината със социално значение. [Doctoral Dissertation]. Medical University of Varna; 2016. Available from: http://eprints.mu-varna.bg/235/

29. Toshev, Ruslan. Significance of Glaucoma Worldwide and in Bulgaria, Screening Possibilities, Early Detection and Analysis of Microstructural Changes /// Глаукомата – значим проблем в България и света, възможности за скрининг, ранно откриване и анализ на промените на микростуктурно ниво.

Degree: phd, Department of Ophthalmology and Visual Sciences, 2014, Medical University of Varna

URL: http://eprints.mu-varna.bg/259/

► [EN] This study aims to explore optimal algorithm options for screening patients with glaucoma on a regional and national level. The possibilities for measuring intraocular… (more)

▼ [EN] This study aims to explore optimal algorithm options for screening patients with glaucoma on a regional and national level. The possibilities for measuring intraocular pressure and assessment of the optic disc were researched and analysed, including routine mass methods which do not require highly specialized equipment. The experimental part of the study involved attempts to correlate corneal microstructural changes in different types of glaucoma and in the course of disease progression. Last but not least, changes in the quality of life of patients suffering from glaucoma were analysed based on a standardized questionnaire. Objective: The main objective of this study was to implement and analyse various screening methods for early detection of glaucoma, both in clinical and experimental conditions, and to develop algorithms applicable for everyday clinical practice. Eight tasks were designated in view of achieving the above objective. Results: To determine accuracy and precision in measurement of the intraocular pressure and its correction based on corneal thickness, 900 measurements were made by two examiners. The average value of the pressure with Tonopachy was 14.69 ± 2.1 mm / Hg, and the corrected value was higher-15.14 ± 2.64 mm / Hg. Values obtained using a Goldmann tonometer were 13.44 ± 4.42 mm / Hg and 14.1 ± 4.21 mm / Hg respectively. Patients’ evaluation raised a total score of 4.27 for Goldmann tonometer combined with ultrasonic pachimetry (regardless the topical anaesthesia), and 3.2 for the examination with air jet tonopahymetre (Tonopachy). The optic nerve evaluation was based on clinical photography, subjectively graded by two examiners, and included a total of 800 values. Subsequently, horizontal and vertical meridian were accurately measured. In clinical / visual assessment of the disc, repeatability of 53% between the two examiners was achieved. Of the remaining 43% there was a deviation of 0.1 in 28% of cases and 0.2 or more in 15% of cases, mostly in the vertical meridian. The results of the two examiners were much closer when measurement was performed, again in 17% of cases there was a disparity of 0.1, mostly on vertical meridian measurement. In eyes with primary open-angle glaucoma - Group 1 (n = 56), and eyes with pseudoexfoliative glaucoma -group 2 (n = 56) with anterior segment optical coherence tomography, central corneal thickness was measured at 531 ± 91 μm (group 1) and 595 ± 28 μm (group 2). Pseudoexfoliations at the posterior surface were clearly visualised. Assessment of the corneal microstructure was done with the aid of confocal microscopy of 30 patients (58 eyes) with no ocular pathology (control), 26 patients (52 eyes) with open-angle glaucoma, 20 patients (33 eyes) with pseudoexfoliation glaucoma and in both eyes of 16 patients with an acute angle closure glaucoma (first clinical presentation). Quantitative measurement of cell numbers in the normal epithelium, anterior and posterior stroma and endothelium were respectively 55555 ± 194 cells / mm ², 342 ± 21 cells /…

Subjects/Keywords: RE Ophthalmology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Toshev, R. (2014). Significance of Glaucoma Worldwide and in Bulgaria, Screening Possibilities, Early Detection and Analysis of Microstructural Changes /// Глаукомата – значим проблем в България и света, възможности за скрининг, ранно откриване и анализ на промените на микростуктурно ниво. (Doctoral Dissertation). Medical University of Varna. Retrieved from http://eprints.mu-varna.bg/259/

Chicago Manual of Style (16^th Edition):

Toshev, Ruslan. “Significance of Glaucoma Worldwide and in Bulgaria, Screening Possibilities, Early Detection and Analysis of Microstructural Changes /// Глаукомата – значим проблем в България и света, възможности за скрининг, ранно откриване и анализ на промените на микростуктурно ниво.” 2014. Doctoral Dissertation, Medical University of Varna. Accessed December 06, 2019. http://eprints.mu-varna.bg/259/.

MLA Handbook (7^th Edition):

Toshev, Ruslan. “Significance of Glaucoma Worldwide and in Bulgaria, Screening Possibilities, Early Detection and Analysis of Microstructural Changes /// Глаукомата – значим проблем в България и света, възможности за скрининг, ранно откриване и анализ на промените на микростуктурно ниво.” 2014. Web. 06 Dec 2019.

Vancouver:

Toshev R. Significance of Glaucoma Worldwide and in Bulgaria, Screening Possibilities, Early Detection and Analysis of Microstructural Changes /// Глаукомата – значим проблем в България и света, възможности за скрининг, ранно откриване и анализ на промените на микростуктурно ниво. [Internet] [Doctoral dissertation]. Medical University of Varna; 2014. [cited 2019 Dec 06]. Available from: http://eprints.mu-varna.bg/259/.

Council of Science Editors:

Toshev R. Significance of Glaucoma Worldwide and in Bulgaria, Screening Possibilities, Early Detection and Analysis of Microstructural Changes /// Глаукомата – значим проблем в България и света, възможности за скрининг, ранно откриване и анализ на промените на микростуктурно ниво. [Doctoral Dissertation]. Medical University of Varna; 2014. Available from: http://eprints.mu-varna.bg/259/

30. Peeva, Svilena. Morphometric Microstructural Analysis of Cornea within the Norm in and in Somatic and Genetic Diseases //// Морфометричен микроструктурен анализ на роговицата в норма и при соматични и генетични заболявания.

Degree: phd, Department of Ophthalmology and Visual Sciences, 2017, Medical University of Varna

URL: http://eprints.mu-varna.bg/335/http://eprints.mu-varna.bg/335/2/ENGLISH%20Extended%20Abstract%20of%20a%20PhD%20thesis.docx

► [EN] The main purpose of this study is to perform an assessment of the living human cornea in healthy subjects by high-tech methods for tomographic… (more)

▼ [EN] The main purpose of this study is to perform an assessment of the living human cornea in healthy subjects by high-tech methods for tomographic and microstructural analysis of healthy cornea and based on this to evaluate pathological changes of the subjects with diabetes with different stages of diabetic retinopathy. In vivo confocal microscopy was used to estimate corneal thickness applying the first image of the endothelium as a standard based on which to evaluate corneal thickness in different age groups and pathological changes of the subjects with diabetes with different stages of diabetic retinopathy. Methods: The major advantage of laser scanning confocal microscope (Heidelberg Retina Tomography II Rostock Corneal Module (HRTII) (Heidelberg, Germany) is the ability to image thin layers (to 10 ?m) of the cornea. To create standards for in vivo confocal microscopy performed with HRT II corneal module and describe characteristics of normal, healthy, human cornea this prospective study included 60 subjects with total of 120 eyes without eye pathology. The inclusion criteria were: no history of eye disease, no contact lens use, no slit-lamp visible corneal pathology, no systemic disease such as diabetes, no current medical treatment and no any surgical eye treatment. The mean age of the patients was 52± 2,9 years (33 women and 27 men). Group I included 52 healthy eyes of 26 subjects, aged 20-26 years; 13 women, 13 men. Group II included 48 healthy eyes of 24 subjects, aged 26-47 years; 54% women and 46% men. Patients were randomly selected by screening and mandatory purpose is subjects have to be healthy without subjective or objective evidence of diseases. Group III included only 20 healthy eyes of 10 subjects aged 50-65 years; 5 women and 5 men. To assess the cornea in subjects with diabetes the study subjects were divided into three groups. The first group are 60 patients without clinical or laboratory evidence of diabetes (33 women and 27 men with a mean age 52±2,9years, aged 22-70 years). The second group of patients with diabetes more than 5 years but without clinical evidence of diabetic retinopathy and neuropathy- 25 subjects (13 women and 12 men with an average age 43.4 ± 2.1, aged 22-65 years). The third group - diabetic patients with diabetic retinopathy, 25 subjects (10 women, 15 men; with an average age 57.9 ± 2.6 years, aged 32-70 years). Results: Analysis reveals that with age progression the number of cells progressively decreases. The average corneal thickness was 0.532±11?m. There is no statistically significant difference between different groups. The average corneal thickness in female subjects is 0.536 ?m which is with 0.004?m more than the male corneal thickness. Conclusion: The current study established corneal changes in different ages and in subjects with diabetes. This approach assessed qualitative changes in cornea which could be used as an analysis of moment status of the cornea. Calculated cell densities of different corneal layers could be used for comparative analysis…

Subjects/Keywords: RE Ophthalmology

Record Details Similar Records Cite « Share

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Peeva, S. (2017). Morphometric Microstructural Analysis of Cornea within the Norm in and in Somatic and Genetic Diseases //// Морфометричен микроструктурен анализ на роговицата в норма и при соматични и генетични заболявания. (Doctoral Dissertation). Medical University of Varna. Retrieved from http://eprints.mu-varna.bg/335/http://eprints.mu-varna.bg/335/2/ENGLISH%20Extended%20Abstract%20of%20a%20PhD%20thesis.docx

Chicago Manual of Style (16^th Edition):

Peeva, Svilena. “Morphometric Microstructural Analysis of Cornea within the Norm in and in Somatic and Genetic Diseases //// Морфометричен микроструктурен анализ на роговицата в норма и при соматични и генетични заболявания.” 2017. Doctoral Dissertation, Medical University of Varna. Accessed December 06, 2019. http://eprints.mu-varna.bg/335/http://eprints.mu-varna.bg/335/2/ENGLISH%20Extended%20Abstract%20of%20a%20PhD%20thesis.docx.

MLA Handbook (7^th Edition):

Peeva, Svilena. “Morphometric Microstructural Analysis of Cornea within the Norm in and in Somatic and Genetic Diseases //// Морфометричен микроструктурен анализ на роговицата в норма и при соматични и генетични заболявания.” 2017. Web. 06 Dec 2019.

Vancouver:

Peeva S. Morphometric Microstructural Analysis of Cornea within the Norm in and in Somatic and Genetic Diseases //// Морфометричен микроструктурен анализ на роговицата в норма и при соматични и генетични заболявания. [Internet] [Doctoral dissertation]. Medical University of Varna; 2017. [cited 2019 Dec 06]. Available from: http://eprints.mu-varna.bg/335/http://eprints.mu-varna.bg/335/2/ENGLISH%20Extended%20Abstract%20of%20a%20PhD%20thesis.docx.

Council of Science Editors:

Peeva S. Morphometric Microstructural Analysis of Cornea within the Norm in and in Somatic and Genetic Diseases //// Морфометричен микроструктурен анализ на роговицата в норма и при соматични и генетични заболявания. [Doctoral Dissertation]. Medical University of Varna; 2017. Available from: http://eprints.mu-varna.bg/335/http://eprints.mu-varna.bg/335/2/ENGLISH%20Extended%20Abstract%20of%20a%20PhD%20thesis.docx

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