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University of Delaware
1.
Caccese, Jaclyn B.
Head acceleration across youth, high school, and collegiate soccer players.
Degree: PhD, 2016, University of Delaware
URL: http://udspace.udel.edu/handle/19716/23614
► Soccer is the most popular sport worldwide with over 265 million active players. Soccer is unique in that you can use your head to advance…
(more)
▼ Soccer is the most popular sport worldwide with over 265 million active players. Soccer is unique in that you can use your
head to advance the ball and purposeful heading is an integral part of the game. However, some have suggested that repeated heading of the soccer ball is associated with neurological deficits, though others have claimed that deficits are related to multiple
head injuries. Still others have observed no neurological deficits. Ultimately, these studies are limited in that they often examine small, homogenous populations. With over 3 million youth soccer players and nearly 1 million high school soccer players competing across the United States each year, more research is needed to determine the risk associated with repeated purposeful heading, particularly among youth and high school athletes. Thus, the purpose of this study was to compare
head acceleration during purposeful soccer heading across age and gender, determine what factors predict higher
head acceleration values, and investigate acute changes in vestibular/ocular function and postural control with purposeful soccer heading. At the collegiate and high school levels, female soccer players exhibited higher
head accelerations than their male counterparts, suggesting that if female soccer players experience a similar number of headers as their male counterparts, females may be exposed to greater cumulative
head accelerations from repeated heading of a soccer ball over a career of soccer. Greater neck girth,
head-neck segment mass, and neck strength predicted lower peak linear and rotational acceleration and may have contributed to the observed gender differences. On average, soccer players presented with higher sway velocity post-heading compared to control participants, but no other group deficits in postural control or vestibular/ocular function were observed.
Advisors/Committee Members: Kaminski, Thomas W..
Subjects/Keywords: Biological sciences; Concussion; Heading; Neck strength; Postural control; Repetitive head impacts; Soccer; Sub-concussion
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APA (6th Edition):
Caccese, J. B. (2016). Head acceleration across youth, high school, and collegiate soccer players. (Doctoral Dissertation). University of Delaware. Retrieved from http://udspace.udel.edu/handle/19716/23614
Chicago Manual of Style (16th Edition):
Caccese, Jaclyn B. “Head acceleration across youth, high school, and collegiate soccer players.” 2016. Doctoral Dissertation, University of Delaware. Accessed January 16, 2021.
http://udspace.udel.edu/handle/19716/23614.
MLA Handbook (7th Edition):
Caccese, Jaclyn B. “Head acceleration across youth, high school, and collegiate soccer players.” 2016. Web. 16 Jan 2021.
Vancouver:
Caccese JB. Head acceleration across youth, high school, and collegiate soccer players. [Internet] [Doctoral dissertation]. University of Delaware; 2016. [cited 2021 Jan 16].
Available from: http://udspace.udel.edu/handle/19716/23614.
Council of Science Editors:
Caccese JB. Head acceleration across youth, high school, and collegiate soccer players. [Doctoral Dissertation]. University of Delaware; 2016. Available from: http://udspace.udel.edu/handle/19716/23614

Boston University
2.
DeVoid, Andrew.
Distinguishing early stage chronic traumatic encephalopathy from persistent post-concussion syndrome.
Degree: MS, Physician Assistant Program, 2017, Boston University
URL: http://hdl.handle.net/2144/26608
► BACKGROUND: Sports-related head trauma has become a major public health concern with significant consequences including persistent post-concussion syndrome (pPCS) and chronic traumatic encephalopathy (CTE). pPCS…
(more)
▼ BACKGROUND: Sports-related head trauma has become a major public health concern with significant consequences including persistent post-concussion syndrome (pPCS) and chronic traumatic encephalopathy (CTE). pPCS is a condition where symptoms of single concussion persist years beyond the initial injury. CTE has been characterized as a condition with insidious onset following a latent period after substantial exposure to repetitive head impacts (RHI). Timing of symptom onset usually distinguishes these conditions, however in certain clinical situations a definitive diagnosis is not always clear. For these situations, a measurable distinguishing variable is necessary.
LITERATURE REVIEW: Concussions are the most common form of traumatic brain injury (TBI) and are associated with a variety of neurological symptoms that usually resolve within weeks. Post-concussion syndrome (PCS) refers to cases where symptoms continue months beyond this window, and pPCS is defined as symptoms continuing over years. These conditions are temporally related single concussive events. CTE is the hallmark condition related to RHI and remains difficult to fully characterize as it currently can only be diagnosed post-mortem. Clinical features of CTE are similar to those of pPCS with notable behavioral/mood symptoms in its earliest stages, and progression to severe cognitive decline over time. Current research has shown executive dysfunction to be a common impairment among these conditions. The difference in level of dysfunction between them, if one exists, is yet to be measured.
PROPOSED PROJECT: A cross-sectional analysis of executive function in four groups. A control without history of mTBI or football exposure (Non-Football – pPCS), a second control of asymptomatic subjects with football exposure (Football – pPCS), a group of pPCS patients with non-athletic mTBI history (Non-Football + pPCS), and a group of pPCS patients with football exposure (Football + pPCS). Executive functioning will be evaluated using the BRIEF-A assessment. Results will be compared to determine if significant differences in executive functioning exist between the groups.
CONCLUSIONS: With previous studies showing a correlation between CTE pathological stage, worsening executive function, and increased RHI exposure, further investigation into using executive function as a distinguishing variable between early stage CTE and pPCS is warranted.
SIGNIFICANCE: Results of this study, if significant, could be applied clinically to assess risk of early stage CTE in athletes with prolonged post-concussion symptoms. If results are not significant, they may still be utilized for a better understanding of the effects of isolated mTBIs and RHI on executive functioning, and provide valuable information for ongoing longitudinal studies.
Subjects/Keywords: Medicine; Chronic traumatic encephalopathy; Concussion; CTE; Post concussion syndrome; Repetitive head impacts; Subconcussion
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APA ·
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MLA ·
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APA (6th Edition):
DeVoid, A. (2017). Distinguishing early stage chronic traumatic encephalopathy from persistent post-concussion syndrome. (Masters Thesis). Boston University. Retrieved from http://hdl.handle.net/2144/26608
Chicago Manual of Style (16th Edition):
DeVoid, Andrew. “Distinguishing early stage chronic traumatic encephalopathy from persistent post-concussion syndrome.” 2017. Masters Thesis, Boston University. Accessed January 16, 2021.
http://hdl.handle.net/2144/26608.
MLA Handbook (7th Edition):
DeVoid, Andrew. “Distinguishing early stage chronic traumatic encephalopathy from persistent post-concussion syndrome.” 2017. Web. 16 Jan 2021.
Vancouver:
DeVoid A. Distinguishing early stage chronic traumatic encephalopathy from persistent post-concussion syndrome. [Internet] [Masters thesis]. Boston University; 2017. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/2144/26608.
Council of Science Editors:
DeVoid A. Distinguishing early stage chronic traumatic encephalopathy from persistent post-concussion syndrome. [Masters Thesis]. Boston University; 2017. Available from: http://hdl.handle.net/2144/26608

Boston University
3.
Duncan, Kristen Marie.
Characterizing the incidence of sleep disorders in a cohort of former college football players.
Degree: MS, Medical Sciences, 2020, Boston University
URL: http://hdl.handle.net/2144/41216
► CTE is a progressive neurodegenerative disease defined by p-tau lesions in characteristic locations of the brain, leading to cognitive impairment as well as mood and…
(more)
▼ CTE is a progressive neurodegenerative disease defined by p-tau lesions in characteristic locations of the brain, leading to cognitive impairment as well as mood and behavioral dysfunction. Exposure to
repetitive head impacts is a major risk factor for developing CTE; however, additional risk factors and secondary modulating factors, which may expand available treatment and prevention options, are still being elucidated. Studies into the glymphatic system, a system of waste clearance in the brain thought to be activated during sleep, have implicated glymphatic dysfunction in the clearance of toxic proteins like amyloid-beta and hyperphosphorylated tau, as well as in cognitive decline in neurodegenerative disorders like Alzheimer’s Disease, bringing into question whether sleep, through impacting glymphatic clearance, may act as a modulating factor in the development of CTE. In the present study, we began to characterize the presence of sleep disorders and their co-morbid conditions in a cohort of former college football players to gain better insight into their prevalence and the health outcomes of those with sleep conditions. Our results found higher rates of sleep apnea in the study sample, as well as an association between diagnosis with sleep apnea and diagnosis with dementia, AD, MCI, CTE, and similar disorders. Sleep apnea was significantly associated with depression, anxiety, high cholesterol, and diabetes. Further research into whether sleep disorders exacerbate CTE pathology or clinical symptoms, and whether treatment of sleep symptoms leads to better outcomes for patients with CTE, is necessary to further elucidate a potential connection.
Advisors/Committee Members: Stern, Robert A. (advisor), Alosco, Michael (advisor).
Subjects/Keywords: Neurosciences; Chronic traumatic encephalopathy; CTE; Dementia; Insomnia; Repetitive head impacts; Sleep disorders
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Duncan, K. M. (2020). Characterizing the incidence of sleep disorders in a cohort of former college football players. (Masters Thesis). Boston University. Retrieved from http://hdl.handle.net/2144/41216
Chicago Manual of Style (16th Edition):
Duncan, Kristen Marie. “Characterizing the incidence of sleep disorders in a cohort of former college football players.” 2020. Masters Thesis, Boston University. Accessed January 16, 2021.
http://hdl.handle.net/2144/41216.
MLA Handbook (7th Edition):
Duncan, Kristen Marie. “Characterizing the incidence of sleep disorders in a cohort of former college football players.” 2020. Web. 16 Jan 2021.
Vancouver:
Duncan KM. Characterizing the incidence of sleep disorders in a cohort of former college football players. [Internet] [Masters thesis]. Boston University; 2020. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/2144/41216.
Council of Science Editors:
Duncan KM. Characterizing the incidence of sleep disorders in a cohort of former college football players. [Masters Thesis]. Boston University; 2020. Available from: http://hdl.handle.net/2144/41216
4.
Forlivio, Steven Joseph.
The effects of repetitive head impacts on neuroimaging and biomarkers in college athletes.
Degree: MS, Physician Assistant Program, 2016, Boston University
URL: http://hdl.handle.net/2144/19183
► Football safety has increased over time, in part due to improvements in equipment and body mechanics, but there are still inherent risks involved, including exposure…
(more)
▼ Football safety has increased over time, in part due to improvements in equipment and body mechanics, but there are still inherent risks involved, including exposure to repetitive head impacts (RHI). Significant head impacts can result in a constellation of symptoms including nausea, vomiting, headache, dizziness, and amnesia, which typically assist in the diagnosis of concussion. However, it has been shown that subconcussive impacts may result in microstructural changes and physiological alterations in the brain. This is particularly concerning because athletes may be undergoing changes in the brain in the absence of outwardly visible symptoms. Poorer neurologic outcomes later in life have been associated with cumulative exposure rather than number of diagnosed concussions. Accelerometers installed in helmets have shown that college football players may receive up to 1,850 head impacts throughout the course of one season. The concussion rate is obviously much lower, indicating there are a high number of head impacts per diagnosed concussion. Axons are especially susceptible to damage from RHI because of their extension throughout the nervous system. The subtle changes thought to result from RHI are not easy to measure, but several modalities have been proposed. These include diffusion tensor imaging (DTI), plasma tau protein, and King-Devick testing. The proposed study will look to quantify cumulative head impact exposure in college football players prior to the start of a season and see if this has any impact on the variables. They will then participate in one season of football wearing helmet accelerometers to measure the number of head impacts sustained. Changes in the variables will be compared to non-contact sport college athletes. Data will be analyzed to determine if number of head impacts correlates with changes in variables and if prior head impact exposure has any effect on these changes. Data obtained from this study will have significant implications in the field of head injury. It may strengthen the use of several markers of brain injury that could be utilized in the future. Additionally, the effects of cumulative head impact exposure and one season of head impacts will be thoroughly examined. This information can be provided to trainers, coaches, and athletes to further improve football safety.
Subjects/Keywords: Neurosciences; Accelerometer; Chronic traumatic encephalopathy; Concussion; Repetitive head impacts; Traumatic brain injury; Tau protein
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Davenport and colleagues conducted a study with many similarities to the…
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Forlivio, S. J. (2016). The effects of repetitive head impacts on neuroimaging and biomarkers in college athletes. (Masters Thesis). Boston University. Retrieved from http://hdl.handle.net/2144/19183
Chicago Manual of Style (16th Edition):
Forlivio, Steven Joseph. “The effects of repetitive head impacts on neuroimaging and biomarkers in college athletes.” 2016. Masters Thesis, Boston University. Accessed January 16, 2021.
http://hdl.handle.net/2144/19183.
MLA Handbook (7th Edition):
Forlivio, Steven Joseph. “The effects of repetitive head impacts on neuroimaging and biomarkers in college athletes.” 2016. Web. 16 Jan 2021.
Vancouver:
Forlivio SJ. The effects of repetitive head impacts on neuroimaging and biomarkers in college athletes. [Internet] [Masters thesis]. Boston University; 2016. [cited 2021 Jan 16].
Available from: http://hdl.handle.net/2144/19183.
Council of Science Editors:
Forlivio SJ. The effects of repetitive head impacts on neuroimaging and biomarkers in college athletes. [Masters Thesis]. Boston University; 2016. Available from: http://hdl.handle.net/2144/19183
5.
Grimes, Katelyn E.
The Effect of Repetitive Head Impacts on Postural Control Over the Course of a Single Season.
Degree: MSin Kinesiology (M.S.), Department of Health and Kinesiology, 2017, Georgia Southern University
URL: https://digitalcommons.georgiasouthern.edu/etd/1563
► INTRODUCTION: Recently neurocognitive dysfunction has been linked to poor postural control in concussed athletes. While the detrimental effect of repetitive head impacts on cognitive…
(more)
▼ INTRODUCTION: Recently neurocognitive dysfunction has been linked to poor postural control in concussed athletes. While the detrimental effect of
repetitive head impacts on cognitive function have been shown to mirror the effects of concussive injury, very little research has investigated the physical consequences of
repetitive head impacts. PURPOSE: To observe the effects of RHI on postural control, both static and dynamic, in NCAA Division I athletes over the course of a single season. METHODS: 9 NCAA Division I football athletes (CON) were recruited from a single university as the experimental group, as well as 9 NCAA Division I baseball players (NON) from the same university to serve as non-contact control group. Subjects’ postural control, measured via a force platform, was tested before and after their fall competitive season using a static postural control assessment and dynamic postural control assessment. The static postural control assessment consisted of eyes open (EO) and eyes closed (EC) quiet standing, while the dynamic postural control assessment consisted of the Wii Fit Soccer Heading Game (WiiSoccer), a sport relevant goal-oriented task. Center of pressure data was used to observed peak excursion velocity (PEV) in the medial-lateral (ML) and anterior-posterior (AP) direction, 95% confidence ellipse (CE), and sample entropy (SampEn) in the ML and AP direction.
Repetitive head impacts were quantified in the CON group using the
Head Impact Telemetry (HIT) System, which is a six-single axis accelerometer helmet unit that was used to record peak linear accelerations. The HIT System was used to quantify the cumulative impact burden (CIB) and average impact magnitude (AIM) among the CON group. RESULTS: Subjects in the CON group experienced a CIB of 1,234.2 g ± 1,0098 g and AIM of 30.7 g ± 6.8 g over the course of 52 practice sessions and 19 game/scrimmage sessions. Repeated measures ANOVA’s revealed a significant difference (p=0.003) in EO SampEn ML between pre (CON: 0.544, NON: 0.548) and post-season testing (CON: 0.433, NON: 0.515). There was also a significant difference (p< 0.001) between pre (CON: 0.657, NON: 0.565) and post-season (CON: 0.548, NON: 0.549). Finally, there was a significant effect (p=0.003) of time by groups in SampEn AP; the CON group had a significantly greater decline between pre (0.657) and post-season (0.548) compared to NON group (0.565 vs. 0.544 respectively). No significant difference was found in the EC or WiiSoccer condition. CONCLUSION: These results suggest that athletic participation does influence static postural control. Nonlinear force plate variables may be the only metrics capable to detecting subtle changes that occur throughout the season. Finally, these results suggest that there was a significant difference between CON and NON during EO condition. This may indicate a deficiency in appropriate integration of visual information, and inability of effective communication between postural control systems during simple tasks in the CON group due to increased exposure…
Advisors/Committee Members: Tamerah Hunt, Barry Munkasy.
Subjects/Keywords: Postural control; repetitive head impacts; Sub-concussive impacts; balance; Biomechanics; Motor Control; Sports Sciences; Jack N. Averitt College of Graduate Studies, Electronic Theses & Dissertations, ETDs, Student Research
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Repetitive head impacts (… …of multiple less severe impacts. The neurocognitive effects of repetitive
head impacts… …frequency of impacts to the top and front of the head during a football season had significantly…
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Grimes, K. E. (2017). The Effect of Repetitive Head Impacts on Postural Control Over the Course of a Single Season. (Masters Thesis). Georgia Southern University. Retrieved from https://digitalcommons.georgiasouthern.edu/etd/1563
Chicago Manual of Style (16th Edition):
Grimes, Katelyn E. “The Effect of Repetitive Head Impacts on Postural Control Over the Course of a Single Season.” 2017. Masters Thesis, Georgia Southern University. Accessed January 16, 2021.
https://digitalcommons.georgiasouthern.edu/etd/1563.
MLA Handbook (7th Edition):
Grimes, Katelyn E. “The Effect of Repetitive Head Impacts on Postural Control Over the Course of a Single Season.” 2017. Web. 16 Jan 2021.
Vancouver:
Grimes KE. The Effect of Repetitive Head Impacts on Postural Control Over the Course of a Single Season. [Internet] [Masters thesis]. Georgia Southern University; 2017. [cited 2021 Jan 16].
Available from: https://digitalcommons.georgiasouthern.edu/etd/1563.
Council of Science Editors:
Grimes KE. The Effect of Repetitive Head Impacts on Postural Control Over the Course of a Single Season. [Masters Thesis]. Georgia Southern University; 2017. Available from: https://digitalcommons.georgiasouthern.edu/etd/1563

University of Western Ontario
6.
Harriss, Alexandra.
Cumulative purposeful soccer heading can lead to compensatory changes in brain activity during combined moderate exercise and cognitive load in female youth soccer players.
Degree: 2020, University of Western Ontario
URL: https://ir.lib.uwo.ca/etd/7262
► Head trauma that occurs during sporting events is responsible for an increasing number of emergency department visits in Canada and is associated with an increased…
(more)
▼ Head trauma that occurs during sporting events is responsible for an increasing number of emergency department visits in Canada and is associated with an increased risk of developing neurodegenerative diseases.While head injury in American football has been extensively studied, it cannot be extrapolated to non-helmeted sports. Approximately 265 million people are actively participating in soccer and many are 18 years of age and younger. Soccer is unique in that players use their head to redirect the ball; however, the effects of cumulative purposeful soccer heading on brain health are unknown. Accordingly, the objective of this thesis was to quantify head impact magnitudes that female youth soccer players sustain during games and evaluate their influence on electrophysiological functioning both at rest and exercise. This was achieved through three research projects that studied female youth soccer players for an entire soccer season and investigated repetitive soccer heading using methodological equipment including, game video analysis, headbands instrumented with wireless microsensors, as well as electroencephalogram (EEG) recordings. Results indicated that the median number of headers experienced during a single game was one, while the maximum is nine, and minimum is zero (Chapter 2). Furthermore, player age is positively associated with an increasing number of purposeful soccer headers, but there is no association between head impact location and game scenario (Chapter 2). Chapter 3 reveals that game scenario and head impact location significantly affect both linear head acceleration and rotational head velocity magnitudes. As an initial attempt to detect neurocognitive change (Chapter 4), EEG recordings revealed a statistically significant increase in EEG power during exercise compared to rest at each EEG frequency band (Alpha1, Alpha2, Beta1, Beta2, Theta). These differences were amplified when cumulative number of headers were considered, but only for Alpha1, Alpha2 and Beta2. In conclusion, this thesis shows cumulative soccer heading experienced by female youth soccer players could lead to neurocognitive changes after one season of soccer. Furthermore, exercise may help to reveal sub-clinical brain changes due to cumulative soccer heading that are not shown at rest. These findings can help guide data-driven approaches to improve player safety in youth soccer.
Subjects/Keywords: Adolescent; concussion; head impacts; brain injury; repetitive; girls; Sports Sciences
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Harriss, A. (2020). Cumulative purposeful soccer heading can lead to compensatory changes in brain activity during combined moderate exercise and cognitive load in female youth soccer players. (Thesis). University of Western Ontario. Retrieved from https://ir.lib.uwo.ca/etd/7262
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Harriss, Alexandra. “Cumulative purposeful soccer heading can lead to compensatory changes in brain activity during combined moderate exercise and cognitive load in female youth soccer players.” 2020. Thesis, University of Western Ontario. Accessed January 16, 2021.
https://ir.lib.uwo.ca/etd/7262.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Harriss, Alexandra. “Cumulative purposeful soccer heading can lead to compensatory changes in brain activity during combined moderate exercise and cognitive load in female youth soccer players.” 2020. Web. 16 Jan 2021.
Vancouver:
Harriss A. Cumulative purposeful soccer heading can lead to compensatory changes in brain activity during combined moderate exercise and cognitive load in female youth soccer players. [Internet] [Thesis]. University of Western Ontario; 2020. [cited 2021 Jan 16].
Available from: https://ir.lib.uwo.ca/etd/7262.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Harriss A. Cumulative purposeful soccer heading can lead to compensatory changes in brain activity during combined moderate exercise and cognitive load in female youth soccer players. [Thesis]. University of Western Ontario; 2020. Available from: https://ir.lib.uwo.ca/etd/7262
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
.