Advanced search options

Advanced Search Options 🞨

Browse by author name (“Author name starts with…”).

Find ETDs with:

in
/  
in
/  
in
/  
in

Written in Published in Earliest date Latest date

Sorted by

Results per page:

Sorted by: relevance · author · university · dateNew search

You searched for subject:(Pseudo rotaxane). Showing records 1 – 2 of 2 total matches.

Search Limiters

Last 2 Years | English Only

No search limiters apply to these results.

▼ Search Limiters


University of Melbourne

1. Ren, Jing Ming. Novel polymeric architectures through controlled/living polymerization, click chemistry and supramolecular interactions.

Degree: 2013, University of Melbourne

The properties and functions of polymeric materials are not only dictated by their composition but also their structural arrangement (i.e., architecture or topology). Exploration of polymers with novel molecular architectures has become a practical strategy for developing advanced soft nanomaterials essential to emerging nanotechnologies. Utilizing a combination of modern synthetic chemistries including controlled/living polymerization, click chemistry and supramolecular interactions, this body of research resulted in the development of facile, versatile and highly efficient synthetic pathways for the preparation of a fascinating array of unprecedented macro(supra)molecular architectures. A scaffold approach that provides access to a library of highly functionalized core cross-linked star (CCS) polymers was developed. Novel functional star macromolecular architectures including fluorescent, saccharide and amphiphilic polyester-based CCS polymers were synthesized by grafting a polyalkyne CCS polymer scaffold with the corresponding azido functional compounds through click chemistry. Factors affecting the grafting efficiency (i.e., click efficiency) of the azido compounds onto the CCS scaffolds were identified. This study not only introduces a versatile and efficient synthetic route towards highly functionalized CCS polymers, but also provides a valuable reference source for the high density functionalization of complex 3-D nanostructures. The near-quantitative synthesis of polyester-based CCS polymers was demonstrated through organic catalyst-mediated ring opening polymerization. Using this innovative approach, novel benzyl and alkyne end-functional polyester-based CCS polymers were conveniently synthesized in high yields (90 - 96%) at ambient temperatures. Side-reactions that are responsible for trace amounts of low molecular weight impurities in the resulting polymers were identified. The established high-yielding system, which involves no toxic metal catalysts or additives and operates under mild reaction conditions with fast reaction rates, represents a powerful synthetic tool for building new functional star macromolecular architectures. In addition to CCS polymers, other functional supra(macro)molecular polymers were also explored. Poly(pseudo)rotaxanes with star and bottlebrush supramolecular structures were constructed via self-assembly of the corresponding guest macromolecules with α-cyclodextrin (CD) through inclusion complexation. The α-CD inclusion complexation was found to be a useful functionalization strategy for the polyester-based (i.e., poly(ε-caprolactone)) guest macromolecules through non-covalent interactions. Such modification not only alters the inherent chemical and physical properties of the guest polymeric materials but also, surprisingly, affects their molecular size and conformation. Lastly, the synthesis of a…

Subjects/Keywords: controlled/living polymerization; click chemistry; supramolecular assembly; polymeric architectures; stereospecific polymerization; stereocomplexes; poly(pseudo)rotaxane; core cross-linked star polymer; cyclic polymer; bottlebrush polymer

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Ren, J. M. (2013). Novel polymeric architectures through controlled/living polymerization, click chemistry and supramolecular interactions. (Doctoral Dissertation). University of Melbourne. Retrieved from http://hdl.handle.net/11343/38668

Chicago Manual of Style (16th Edition):

Ren, Jing Ming. “Novel polymeric architectures through controlled/living polymerization, click chemistry and supramolecular interactions.” 2013. Doctoral Dissertation, University of Melbourne. Accessed July 21, 2019. http://hdl.handle.net/11343/38668.

MLA Handbook (7th Edition):

Ren, Jing Ming. “Novel polymeric architectures through controlled/living polymerization, click chemistry and supramolecular interactions.” 2013. Web. 21 Jul 2019.

Vancouver:

Ren JM. Novel polymeric architectures through controlled/living polymerization, click chemistry and supramolecular interactions. [Internet] [Doctoral dissertation]. University of Melbourne; 2013. [cited 2019 Jul 21]. Available from: http://hdl.handle.net/11343/38668.

Council of Science Editors:

Ren JM. Novel polymeric architectures through controlled/living polymerization, click chemistry and supramolecular interactions. [Doctoral Dissertation]. University of Melbourne; 2013. Available from: http://hdl.handle.net/11343/38668

2. Wang, Xiang. Orchestration de l'auto-assemblage et des mouvements moléculaires de pseudo-rotaxanes helicoïdaux : Orchestration of the self-assembly and molecular motion of helical pseudorotaxanes.

Degree: Docteur es, Chimie organique, 2016, Bordeaux

L’orchestration des mouvements directionnels d’architectures supramoléculaires s’avère cruciale pour la préparation de machines moléculaires artificielles. Les oligomères d’amides aromatiques (i.e. foldamères) peuvent adopter des conformations stables capables de se complexer à des tiges moléculaires pour former des (pseudo)-rotaxanes. Un contrôle fin des cinétiques d’association et de dissociation de l’hélice autour de la tige permet à l’oligomère hélicoïdal de glisser le long de celle-ci sans dissociation. Des études RMN et cristallographiques ont montré que des tiges moléculaires possédant plusieurs sites de reconnaissance pour des hélices permettaient l’élaboration d’architectures supramoléculaires hélicoïdales chirales avec une haute-fidélité. Chaque station possédant une longueur et une chiralité définie peut induire la complexation de foldamères de taille et d’hélicité concordante. Le glissement directionnel d’une double hélice le long d’une tige possédant plusieurs stations a également été investigué. Insérer un espaceur encombrant (i.e. plus large que la cavité de l’hélice) sur le chemin du foldamère le force à se déplier et se replier pour atteindre le site le plus favorable thermodynamiquement. Un oligomère asymétrique montrant de hautes affinités et de fortes sélectivités pour des tiges asymétriques a été préparé. L’enfilement de cet oligomère sur des tiges asymétriques a été étudié. Des données cinétiques (RMN) indiquent que l’enfilement de celui-ci s’effectue de façon polarisée en fonction de la nature de la tige.

The directional motion orchestration of supramolecular architectures is crucial for the construction of artificial molecular machines. Aromatic amide oligomers (i.e. foldamers) can adopt stable helical conformations able to wind around dumbbell-like guests to form (pseudo)-rotaxanes. A fine control of the association-dissociation kinetics allows the oligomers to slide along the rods without dissociation. In this thesis, based on the segregation of the kinetics of association-dissociation and sliding, helical oligomer motions were orchestrated to form complex self-assemblies and to perform directional motion. NMR and crystallographic studies showed that multistation rod guests can template the formation of well-defined multi-helical supramolecular polymers with high fidelity. Each station possessing a defined length and chirality can induce the complexation of oligomers presenting matching length and chirality. Directional sliding of a double helical oligomer along linear multistation rod guests was investigated. Placing a bulky spacer on the rod prohibits the sliding process, forcing the oligomer to dissociate and reassociate onto the thermodynamically favored station. An asymmetrical oligomer was prepared showing highly selective binding toward asymmetrical rod guests. The threading of this oligomer onto linear asymmetrical guests was investigated. Kinetic data indicated that the threading orientation of this asymmetrical oligomer was polarized by its passage along guest molecules.

Advisors/Committee Members: Huc, Ivan (thesis director), Ferrand, Yann (thesis director).

Subjects/Keywords: Foldamère; Hélice; Pseudo-rotaxane; Auto-assemblage; Mouvement directionnel; Chimie hôte-invité; Reconnaissance moléculaire; Machine moléculaire; Cristallographie; RMN; Foldamer; Helix; Pseudorotaxane; Self-assembly; Directional motion; Host-guest chemistry; Molecular recognition; Molecular machine; Crystallography; NMR

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Wang, X. (2016). Orchestration de l'auto-assemblage et des mouvements moléculaires de pseudo-rotaxanes helicoïdaux : Orchestration of the self-assembly and molecular motion of helical pseudorotaxanes. (Doctoral Dissertation). Bordeaux. Retrieved from http://www.theses.fr/2016BORD0076

Chicago Manual of Style (16th Edition):

Wang, Xiang. “Orchestration de l'auto-assemblage et des mouvements moléculaires de pseudo-rotaxanes helicoïdaux : Orchestration of the self-assembly and molecular motion of helical pseudorotaxanes.” 2016. Doctoral Dissertation, Bordeaux. Accessed July 21, 2019. http://www.theses.fr/2016BORD0076.

MLA Handbook (7th Edition):

Wang, Xiang. “Orchestration de l'auto-assemblage et des mouvements moléculaires de pseudo-rotaxanes helicoïdaux : Orchestration of the self-assembly and molecular motion of helical pseudorotaxanes.” 2016. Web. 21 Jul 2019.

Vancouver:

Wang X. Orchestration de l'auto-assemblage et des mouvements moléculaires de pseudo-rotaxanes helicoïdaux : Orchestration of the self-assembly and molecular motion of helical pseudorotaxanes. [Internet] [Doctoral dissertation]. Bordeaux; 2016. [cited 2019 Jul 21]. Available from: http://www.theses.fr/2016BORD0076.

Council of Science Editors:

Wang X. Orchestration de l'auto-assemblage et des mouvements moléculaires de pseudo-rotaxanes helicoïdaux : Orchestration of the self-assembly and molecular motion of helical pseudorotaxanes. [Doctoral Dissertation]. Bordeaux; 2016. Available from: http://www.theses.fr/2016BORD0076

.