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University: University of Manchester

You searched for subject:(Protein Engineering). Showing records 1 – 21 of 21 total matches.

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University of Manchester

1. Hulley, Martyn. Engineering of the PETNR active site to accommodate novel α/β substituted enone substrates.

Degree: 2010, University of Manchester

 Experiments facilitating the engineering of the PETNR active site to accommodate a range of non natural enone substrates with substituents localised on the α and… (more)

Subjects/Keywords: Biocatalysis; protein engineering

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APA (6th Edition):

Hulley, M. (2010). Engineering of the PETNR active site to accommodate novel α/β substituted enone substrates. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:96347

Chicago Manual of Style (16th Edition):

Hulley, Martyn. “Engineering of the PETNR active site to accommodate novel α/β substituted enone substrates.” 2010. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:96347.

MLA Handbook (7th Edition):

Hulley, Martyn. “Engineering of the PETNR active site to accommodate novel α/β substituted enone substrates.” 2010. Web. 07 Jul 2020.

Vancouver:

Hulley M. Engineering of the PETNR active site to accommodate novel α/β substituted enone substrates. [Internet] [Doctoral dissertation]. University of Manchester; 2010. [cited 2020 Jul 07]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:96347.

Council of Science Editors:

Hulley M. Engineering of the PETNR active site to accommodate novel α/β substituted enone substrates. [Doctoral Dissertation]. University of Manchester; 2010. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:96347


University of Manchester

2. Hugentobler, Katharina. Development of new biocatalytic routes to pharmaceutical intermediates: a case study on ticagrelor.

Degree: 2014, University of Manchester

The research carried out within this thesis was aimed at the development andimplementation of a biocatalytic route towards Ticagrelor, a platelet-aggregationinhibitor. A bio-retrosynthetic consideration of… (more)

Subjects/Keywords: biocatalysis; protein engineering

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APA (6th Edition):

Hugentobler, K. (2014). Development of new biocatalytic routes to pharmaceutical intermediates: a case study on ticagrelor. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:240647

Chicago Manual of Style (16th Edition):

Hugentobler, Katharina. “Development of new biocatalytic routes to pharmaceutical intermediates: a case study on ticagrelor.” 2014. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:240647.

MLA Handbook (7th Edition):

Hugentobler, Katharina. “Development of new biocatalytic routes to pharmaceutical intermediates: a case study on ticagrelor.” 2014. Web. 07 Jul 2020.

Vancouver:

Hugentobler K. Development of new biocatalytic routes to pharmaceutical intermediates: a case study on ticagrelor. [Internet] [Doctoral dissertation]. University of Manchester; 2014. [cited 2020 Jul 07]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:240647.

Council of Science Editors:

Hugentobler K. Development of new biocatalytic routes to pharmaceutical intermediates: a case study on ticagrelor. [Doctoral Dissertation]. University of Manchester; 2014. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:240647


University of Manchester

3. Hugentobler, Katharina. Development of new biocatalytic routes to pharmaceutical intermediates : a case study on Ticagrelor.

Degree: PhD, 2014, University of Manchester

 The research carried out within this thesis was aimed at the development and implementation of a biocatalytic route towards Ticagrelor, a platelet-aggregation inhibitor. A bio-retrosynthetic… (more)

Subjects/Keywords: 660.6; biocatalysis; protein engineering

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APA (6th Edition):

Hugentobler, K. (2014). Development of new biocatalytic routes to pharmaceutical intermediates : a case study on Ticagrelor. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/development-of-new-biocatalytic-routes-to-pharmaceutical-intermediates-a-case-study-on-ticagrelor(0bda5532-3713-406b-873b-a40ee0d26a33).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.677730

Chicago Manual of Style (16th Edition):

Hugentobler, Katharina. “Development of new biocatalytic routes to pharmaceutical intermediates : a case study on Ticagrelor.” 2014. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. https://www.research.manchester.ac.uk/portal/en/theses/development-of-new-biocatalytic-routes-to-pharmaceutical-intermediates-a-case-study-on-ticagrelor(0bda5532-3713-406b-873b-a40ee0d26a33).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.677730.

MLA Handbook (7th Edition):

Hugentobler, Katharina. “Development of new biocatalytic routes to pharmaceutical intermediates : a case study on Ticagrelor.” 2014. Web. 07 Jul 2020.

Vancouver:

Hugentobler K. Development of new biocatalytic routes to pharmaceutical intermediates : a case study on Ticagrelor. [Internet] [Doctoral dissertation]. University of Manchester; 2014. [cited 2020 Jul 07]. Available from: https://www.research.manchester.ac.uk/portal/en/theses/development-of-new-biocatalytic-routes-to-pharmaceutical-intermediates-a-case-study-on-ticagrelor(0bda5532-3713-406b-873b-a40ee0d26a33).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.677730.

Council of Science Editors:

Hugentobler K. Development of new biocatalytic routes to pharmaceutical intermediates : a case study on Ticagrelor. [Doctoral Dissertation]. University of Manchester; 2014. Available from: https://www.research.manchester.ac.uk/portal/en/theses/development-of-new-biocatalytic-routes-to-pharmaceutical-intermediates-a-case-study-on-ticagrelor(0bda5532-3713-406b-873b-a40ee0d26a33).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.677730


University of Manchester

4. Aleku, Godwin Abazho. Development of Imine Reductases and Reductive Aminases for Chiral Amine Synthesis.

Degree: 2017, University of Manchester

 Novel biocatalysts for the enantioselective reduction of imines and reductive amination of a broad range of carbonyl compounds have been developed. Unlike other imine reductases… (more)

Subjects/Keywords: Imine reductases, reductive aminases, biocatalysis, biotransformation; protein engineering, catalysis, kinetic resolution

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APA (6th Edition):

Aleku, G. A. (2017). Development of Imine Reductases and Reductive Aminases for Chiral Amine Synthesis. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:308486

Chicago Manual of Style (16th Edition):

Aleku, Godwin Abazho. “Development of Imine Reductases and Reductive Aminases for Chiral Amine Synthesis.” 2017. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:308486.

MLA Handbook (7th Edition):

Aleku, Godwin Abazho. “Development of Imine Reductases and Reductive Aminases for Chiral Amine Synthesis.” 2017. Web. 07 Jul 2020.

Vancouver:

Aleku GA. Development of Imine Reductases and Reductive Aminases for Chiral Amine Synthesis. [Internet] [Doctoral dissertation]. University of Manchester; 2017. [cited 2020 Jul 07]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:308486.

Council of Science Editors:

Aleku GA. Development of Imine Reductases and Reductive Aminases for Chiral Amine Synthesis. [Doctoral Dissertation]. University of Manchester; 2017. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:308486


University of Manchester

5. Craddock, Russell James. Structural Characterisation of Aggrecan in Cartilaginous Tissues and Tissue Engineered Constructs.

Degree: 2017, University of Manchester

 Collagen II and the proteoglycan aggrecan are key extracellular matrix (ECM) proteins in cartilaginous tissues such as the intervertebral disc (IVD). Given the functional role… (more)

Subjects/Keywords: Aggrecan; Protein characterisation; Atomic force microscopy; mechanics; tissue engineering

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APA (6th Edition):

Craddock, R. J. (2017). Structural Characterisation of Aggrecan in Cartilaginous Tissues and Tissue Engineered Constructs. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:312557

Chicago Manual of Style (16th Edition):

Craddock, Russell James. “Structural Characterisation of Aggrecan in Cartilaginous Tissues and Tissue Engineered Constructs.” 2017. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:312557.

MLA Handbook (7th Edition):

Craddock, Russell James. “Structural Characterisation of Aggrecan in Cartilaginous Tissues and Tissue Engineered Constructs.” 2017. Web. 07 Jul 2020.

Vancouver:

Craddock RJ. Structural Characterisation of Aggrecan in Cartilaginous Tissues and Tissue Engineered Constructs. [Internet] [Doctoral dissertation]. University of Manchester; 2017. [cited 2020 Jul 07]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:312557.

Council of Science Editors:

Craddock RJ. Structural Characterisation of Aggrecan in Cartilaginous Tissues and Tissue Engineered Constructs. [Doctoral Dissertation]. University of Manchester; 2017. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:312557


University of Manchester

6. Povsic, Manca. Rational redesign of cytochrome P450 BM3 (CYP102A1) towards industrially relevant drug metabolites.

Degree: 2015, University of Manchester

 The University of ManchesterManca PovsicRational redesign of cytochrome P450 BM3 (CYP102A1) towards industrially relevant drug metabolitesSeptember 2015Human drug metabolites are frequently biologically active, with many… (more)

Subjects/Keywords: cytochrome P450; P450 BM3; drug metabolites; protein engineering; biotechnology

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APA (6th Edition):

Povsic, M. (2015). Rational redesign of cytochrome P450 BM3 (CYP102A1) towards industrially relevant drug metabolites. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:293526

Chicago Manual of Style (16th Edition):

Povsic, Manca. “Rational redesign of cytochrome P450 BM3 (CYP102A1) towards industrially relevant drug metabolites.” 2015. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:293526.

MLA Handbook (7th Edition):

Povsic, Manca. “Rational redesign of cytochrome P450 BM3 (CYP102A1) towards industrially relevant drug metabolites.” 2015. Web. 07 Jul 2020.

Vancouver:

Povsic M. Rational redesign of cytochrome P450 BM3 (CYP102A1) towards industrially relevant drug metabolites. [Internet] [Doctoral dissertation]. University of Manchester; 2015. [cited 2020 Jul 07]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:293526.

Council of Science Editors:

Povsic M. Rational redesign of cytochrome P450 BM3 (CYP102A1) towards industrially relevant drug metabolites. [Doctoral Dissertation]. University of Manchester; 2015. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:293526


University of Manchester

7. Hulley, Martyn. Engineering of the PETNR active site to accommodate novel α/β substituted enone substrates.

Degree: PhD, 2010, University of Manchester

 Experiments facilitating the engineering of the PETNR active site to accommodate a range of non natural enone substrates with substituents localised on the α and… (more)

Subjects/Keywords: 572.8; Biocatalysis; protein engineering

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Hulley, M. (2010). Engineering of the PETNR active site to accommodate novel α/β substituted enone substrates. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/engineering-of-the-petnr-active-site-to-accommodate-novel-alpha-substituted-enone-substrates(31c4828a-4f90-495a-8ab5-afbcb0482baf).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.529217

Chicago Manual of Style (16th Edition):

Hulley, Martyn. “Engineering of the PETNR active site to accommodate novel α/β substituted enone substrates.” 2010. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. https://www.research.manchester.ac.uk/portal/en/theses/engineering-of-the-petnr-active-site-to-accommodate-novel-alpha-substituted-enone-substrates(31c4828a-4f90-495a-8ab5-afbcb0482baf).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.529217.

MLA Handbook (7th Edition):

Hulley, Martyn. “Engineering of the PETNR active site to accommodate novel α/β substituted enone substrates.” 2010. Web. 07 Jul 2020.

Vancouver:

Hulley M. Engineering of the PETNR active site to accommodate novel α/β substituted enone substrates. [Internet] [Doctoral dissertation]. University of Manchester; 2010. [cited 2020 Jul 07]. Available from: https://www.research.manchester.ac.uk/portal/en/theses/engineering-of-the-petnr-active-site-to-accommodate-novel-alpha-substituted-enone-substrates(31c4828a-4f90-495a-8ab5-afbcb0482baf).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.529217.

Council of Science Editors:

Hulley M. Engineering of the PETNR active site to accommodate novel α/β substituted enone substrates. [Doctoral Dissertation]. University of Manchester; 2010. Available from: https://www.research.manchester.ac.uk/portal/en/theses/engineering-of-the-petnr-active-site-to-accommodate-novel-alpha-substituted-enone-substrates(31c4828a-4f90-495a-8ab5-afbcb0482baf).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.529217


University of Manchester

8. Povsic, Manca. Rational redesign of cytochrome P450 BM3 (CYP102A1) towards industrially relevant drug metabolites.

Degree: PhD, 2016, University of Manchester

 Human drug metabolites are frequently biologically active, with many implications for human health. Pharmaceutical companies have become increasingly aware of the need to identify and… (more)

Subjects/Keywords: cytochrome P450; P450 BM3; drug metabolites; protein engineering; biotechnology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Povsic, M. (2016). Rational redesign of cytochrome P450 BM3 (CYP102A1) towards industrially relevant drug metabolites. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/rational-redesign-of-cytochrome-p450-bm3-cyp102a1-towards-industrially-relevant-drug-metabolites(1e9b4e44-0211-4ffc-8684-7db1c9a21791).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.764467

Chicago Manual of Style (16th Edition):

Povsic, Manca. “Rational redesign of cytochrome P450 BM3 (CYP102A1) towards industrially relevant drug metabolites.” 2016. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. https://www.research.manchester.ac.uk/portal/en/theses/rational-redesign-of-cytochrome-p450-bm3-cyp102a1-towards-industrially-relevant-drug-metabolites(1e9b4e44-0211-4ffc-8684-7db1c9a21791).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.764467.

MLA Handbook (7th Edition):

Povsic, Manca. “Rational redesign of cytochrome P450 BM3 (CYP102A1) towards industrially relevant drug metabolites.” 2016. Web. 07 Jul 2020.

Vancouver:

Povsic M. Rational redesign of cytochrome P450 BM3 (CYP102A1) towards industrially relevant drug metabolites. [Internet] [Doctoral dissertation]. University of Manchester; 2016. [cited 2020 Jul 07]. Available from: https://www.research.manchester.ac.uk/portal/en/theses/rational-redesign-of-cytochrome-p450-bm3-cyp102a1-towards-industrially-relevant-drug-metabolites(1e9b4e44-0211-4ffc-8684-7db1c9a21791).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.764467.

Council of Science Editors:

Povsic M. Rational redesign of cytochrome P450 BM3 (CYP102A1) towards industrially relevant drug metabolites. [Doctoral Dissertation]. University of Manchester; 2016. Available from: https://www.research.manchester.ac.uk/portal/en/theses/rational-redesign-of-cytochrome-p450-bm3-cyp102a1-towards-industrially-relevant-drug-metabolites(1e9b4e44-0211-4ffc-8684-7db1c9a21791).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.764467


University of Manchester

9. Menon, Navya. Kinetics and structure-guided characterisation and engineering of Aldehyde deformylating oxygenase (ADO) for a renewable microbial biofuel platform.

Degree: 2015, University of Manchester

 The increased demand for an alternative form of fuel has raised a great interest towards exploring various metabolic pathways and enzymes in several microbial species… (more)

Subjects/Keywords: Biofuels, Aldehyde deformylating oxygenase (ADO), Enzymes,; Clostridial butanol pathway, Propane, Direct-fuel, Protein engineering

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APA (6th Edition):

Menon, N. (2015). Kinetics and structure-guided characterisation and engineering of Aldehyde deformylating oxygenase (ADO) for a renewable microbial biofuel platform. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:266312

Chicago Manual of Style (16th Edition):

Menon, Navya. “Kinetics and structure-guided characterisation and engineering of Aldehyde deformylating oxygenase (ADO) for a renewable microbial biofuel platform.” 2015. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:266312.

MLA Handbook (7th Edition):

Menon, Navya. “Kinetics and structure-guided characterisation and engineering of Aldehyde deformylating oxygenase (ADO) for a renewable microbial biofuel platform.” 2015. Web. 07 Jul 2020.

Vancouver:

Menon N. Kinetics and structure-guided characterisation and engineering of Aldehyde deformylating oxygenase (ADO) for a renewable microbial biofuel platform. [Internet] [Doctoral dissertation]. University of Manchester; 2015. [cited 2020 Jul 07]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:266312.

Council of Science Editors:

Menon N. Kinetics and structure-guided characterisation and engineering of Aldehyde deformylating oxygenase (ADO) for a renewable microbial biofuel platform. [Doctoral Dissertation]. University of Manchester; 2015. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:266312


University of Manchester

10. Menon, Navya. Kinetics and structure-guided characterisation and engineering of aldehyde deformylating oxygenase (ADO) for a renewable microbial biofuel platform.

Degree: PhD, 2015, University of Manchester

 The increased demand for an alternative form of fuel has raised a great interest towards exploring various metabolic pathways and enzymes in several microbial species… (more)

Subjects/Keywords: 579; Clostridial butanol pathway; Propane; Direct-fuel; Protein engineering; Biofuels; Aldehyde deformylating oxygenase (ADO); Enzymes

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Menon, N. (2015). Kinetics and structure-guided characterisation and engineering of aldehyde deformylating oxygenase (ADO) for a renewable microbial biofuel platform. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/kinetics-and-structureguided-characterisation-and-engineering-of-aldehyde-deformylating-oxygenase-ado-for-a-renewable-microbial-biofuel-platform(a1475b84-ae69-4488-bcc4-c840d662af4a).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.719280

Chicago Manual of Style (16th Edition):

Menon, Navya. “Kinetics and structure-guided characterisation and engineering of aldehyde deformylating oxygenase (ADO) for a renewable microbial biofuel platform.” 2015. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. https://www.research.manchester.ac.uk/portal/en/theses/kinetics-and-structureguided-characterisation-and-engineering-of-aldehyde-deformylating-oxygenase-ado-for-a-renewable-microbial-biofuel-platform(a1475b84-ae69-4488-bcc4-c840d662af4a).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.719280.

MLA Handbook (7th Edition):

Menon, Navya. “Kinetics and structure-guided characterisation and engineering of aldehyde deformylating oxygenase (ADO) for a renewable microbial biofuel platform.” 2015. Web. 07 Jul 2020.

Vancouver:

Menon N. Kinetics and structure-guided characterisation and engineering of aldehyde deformylating oxygenase (ADO) for a renewable microbial biofuel platform. [Internet] [Doctoral dissertation]. University of Manchester; 2015. [cited 2020 Jul 07]. Available from: https://www.research.manchester.ac.uk/portal/en/theses/kinetics-and-structureguided-characterisation-and-engineering-of-aldehyde-deformylating-oxygenase-ado-for-a-renewable-microbial-biofuel-platform(a1475b84-ae69-4488-bcc4-c840d662af4a).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.719280.

Council of Science Editors:

Menon N. Kinetics and structure-guided characterisation and engineering of aldehyde deformylating oxygenase (ADO) for a renewable microbial biofuel platform. [Doctoral Dissertation]. University of Manchester; 2015. Available from: https://www.research.manchester.ac.uk/portal/en/theses/kinetics-and-structureguided-characterisation-and-engineering-of-aldehyde-deformylating-oxygenase-ado-for-a-renewable-microbial-biofuel-platform(a1475b84-ae69-4488-bcc4-c840d662af4a).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.719280


University of Manchester

11. Herrera Rodriguez, Leopoldo. Genetic engineering tools for transforming the nucleus and chloroplast of microalgae.

Degree: PhD, 2017, University of Manchester

 Biotechnology of microalgae is a fast-growing field and several species have become targets for transgenic manipulation. Microalgae provide low-cost and scalable production platforms for manufacturing… (more)

Subjects/Keywords: 579.8; chloroplast; transformation; synthetic biology; genetic engineering; protein expression; dunaliella; chlamydomonas; microalgae

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APA (6th Edition):

Herrera Rodriguez, L. (2017). Genetic engineering tools for transforming the nucleus and chloroplast of microalgae. (Doctoral Dissertation). University of Manchester. Retrieved from https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.727988

Chicago Manual of Style (16th Edition):

Herrera Rodriguez, Leopoldo. “Genetic engineering tools for transforming the nucleus and chloroplast of microalgae.” 2017. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.727988.

MLA Handbook (7th Edition):

Herrera Rodriguez, Leopoldo. “Genetic engineering tools for transforming the nucleus and chloroplast of microalgae.” 2017. Web. 07 Jul 2020.

Vancouver:

Herrera Rodriguez L. Genetic engineering tools for transforming the nucleus and chloroplast of microalgae. [Internet] [Doctoral dissertation]. University of Manchester; 2017. [cited 2020 Jul 07]. Available from: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.727988.

Council of Science Editors:

Herrera Rodriguez L. Genetic engineering tools for transforming the nucleus and chloroplast of microalgae. [Doctoral Dissertation]. University of Manchester; 2017. Available from: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.727988


University of Manchester

12. Tavanti, Michele. Discovery, engineering and application of self-sufficient P450s for biocatalysis.

Degree: PhD, 2019, University of Manchester

 Cytochrome P450 monooxygenases (P450s) are a widespread class of enzymes involved in biosynthetic pathways and drug metabolism. They can catalyse a diverse range of challenging… (more)

Subjects/Keywords: C-H activation; Reductive aminases; Crystallography; Alcohol dehydrogenases; Biocatalysis; Protein engineering; P450 monooxygenases; Enzyme cascades

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APA (6th Edition):

Tavanti, M. (2019). Discovery, engineering and application of self-sufficient P450s for biocatalysis. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/discovery-engineering-and-application-of-selfsufficient-p450s-for-biocatalysis(d8dfdcc9-f660-49a8-bc81-2ead4fc1db66).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.799409

Chicago Manual of Style (16th Edition):

Tavanti, Michele. “Discovery, engineering and application of self-sufficient P450s for biocatalysis.” 2019. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. https://www.research.manchester.ac.uk/portal/en/theses/discovery-engineering-and-application-of-selfsufficient-p450s-for-biocatalysis(d8dfdcc9-f660-49a8-bc81-2ead4fc1db66).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.799409.

MLA Handbook (7th Edition):

Tavanti, Michele. “Discovery, engineering and application of self-sufficient P450s for biocatalysis.” 2019. Web. 07 Jul 2020.

Vancouver:

Tavanti M. Discovery, engineering and application of self-sufficient P450s for biocatalysis. [Internet] [Doctoral dissertation]. University of Manchester; 2019. [cited 2020 Jul 07]. Available from: https://www.research.manchester.ac.uk/portal/en/theses/discovery-engineering-and-application-of-selfsufficient-p450s-for-biocatalysis(d8dfdcc9-f660-49a8-bc81-2ead4fc1db66).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.799409.

Council of Science Editors:

Tavanti M. Discovery, engineering and application of self-sufficient P450s for biocatalysis. [Doctoral Dissertation]. University of Manchester; 2019. Available from: https://www.research.manchester.ac.uk/portal/en/theses/discovery-engineering-and-application-of-selfsufficient-p450s-for-biocatalysis(d8dfdcc9-f660-49a8-bc81-2ead4fc1db66).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.799409


University of Manchester

13. Tavanti, Michele. Discovery, Engineering and Application of Self-Sufficient P450s for Biocatalysis.

Degree: 2019, University of Manchester

 Cytochrome P450 monooxygenases (P450s) are a widespread class of enzymes involved in biosynthetic pathways and drug metabolism. They can catalyse a diverse range of challenging… (more)

Subjects/Keywords: Biocatalysis; C-H activation; P450 monooxygenases; Protein engineering; Enzyme cascades; Alcohol dehydrogenases; Reductive aminases; Crystallography

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Tavanti, M. (2019). Discovery, Engineering and Application of Self-Sufficient P450s for Biocatalysis. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:317920

Chicago Manual of Style (16th Edition):

Tavanti, Michele. “Discovery, Engineering and Application of Self-Sufficient P450s for Biocatalysis.” 2019. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:317920.

MLA Handbook (7th Edition):

Tavanti, Michele. “Discovery, Engineering and Application of Self-Sufficient P450s for Biocatalysis.” 2019. Web. 07 Jul 2020.

Vancouver:

Tavanti M. Discovery, Engineering and Application of Self-Sufficient P450s for Biocatalysis. [Internet] [Doctoral dissertation]. University of Manchester; 2019. [cited 2020 Jul 07]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:317920.

Council of Science Editors:

Tavanti M. Discovery, Engineering and Application of Self-Sufficient P450s for Biocatalysis. [Doctoral Dissertation]. University of Manchester; 2019. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:317920


University of Manchester

14. Ashworth, Mark. Structure-based engineering of CYP105AS1 for the production of high-value molecules.

Degree: PhD, 2018, University of Manchester

 Biocatalysis represents an attractive route to the production of various compounds which are difficult or impossible to synthesise and isolate using traditional chemical synthesis. In… (more)

Subjects/Keywords: 540; Statins; Pravastatin; Biocatalysis; CYP105AS1; Cytochrome P450; Biotechnology; Enzyme engineering; Computational enzyme design; Protein engineering; Synthetic biology; Enantioselectivity

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Ashworth, M. (2018). Structure-based engineering of CYP105AS1 for the production of high-value molecules. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/structurebased-engineering-of-cyp105as1-for-the-production-of-highvalue-molecules(2e7a9ade-a21e-4138-a692-e84541b517ce).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740368

Chicago Manual of Style (16th Edition):

Ashworth, Mark. “Structure-based engineering of CYP105AS1 for the production of high-value molecules.” 2018. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. https://www.research.manchester.ac.uk/portal/en/theses/structurebased-engineering-of-cyp105as1-for-the-production-of-highvalue-molecules(2e7a9ade-a21e-4138-a692-e84541b517ce).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740368.

MLA Handbook (7th Edition):

Ashworth, Mark. “Structure-based engineering of CYP105AS1 for the production of high-value molecules.” 2018. Web. 07 Jul 2020.

Vancouver:

Ashworth M. Structure-based engineering of CYP105AS1 for the production of high-value molecules. [Internet] [Doctoral dissertation]. University of Manchester; 2018. [cited 2020 Jul 07]. Available from: https://www.research.manchester.ac.uk/portal/en/theses/structurebased-engineering-of-cyp105as1-for-the-production-of-highvalue-molecules(2e7a9ade-a21e-4138-a692-e84541b517ce).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740368.

Council of Science Editors:

Ashworth M. Structure-based engineering of CYP105AS1 for the production of high-value molecules. [Doctoral Dissertation]. University of Manchester; 2018. Available from: https://www.research.manchester.ac.uk/portal/en/theses/structurebased-engineering-of-cyp105as1-for-the-production-of-highvalue-molecules(2e7a9ade-a21e-4138-a692-e84541b517ce).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740368

15. Haji Ruslan, Khairunnisa Nabilah. PROTEIN HYDROGELS AS TISSUE ENGINEERING SCAFFOLDS.

Degree: 2015, University of Manchester

 Hydrogels aim to mimic the natural living environment by entrapping large amount of water or biological fluids in their polymeric network. There has been growing… (more)

Subjects/Keywords: Hydrogels; Protein Hydrogels; HEWL; HEWL-PNIPAAm; Tissue Engineering; Scaffolds

Protein Hydrogels as Tissue Engineering Scaffolds”, submitted by Khairunnisa Nabilah Haji Ruslan… …engineering scaffolds. It also considers the formation of protein hydrogels in terms of the gelation… …molecules and the interior of protein patches. 2.3.2.2 Lysozyme hydrogels as a tissue engineering… …30 Figure 2.8 Possible routes to protein-polymer conjugation… …Figure 3.5 Schematic representing the click approach to polymer-protein bioconjugate.... 39… 

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Haji Ruslan, K. N. (2015). PROTEIN HYDROGELS AS TISSUE ENGINEERING SCAFFOLDS. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:262195

Chicago Manual of Style (16th Edition):

Haji Ruslan, Khairunnisa Nabilah. “PROTEIN HYDROGELS AS TISSUE ENGINEERING SCAFFOLDS.” 2015. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:262195.

MLA Handbook (7th Edition):

Haji Ruslan, Khairunnisa Nabilah. “PROTEIN HYDROGELS AS TISSUE ENGINEERING SCAFFOLDS.” 2015. Web. 07 Jul 2020.

Vancouver:

Haji Ruslan KN. PROTEIN HYDROGELS AS TISSUE ENGINEERING SCAFFOLDS. [Internet] [Doctoral dissertation]. University of Manchester; 2015. [cited 2020 Jul 07]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:262195.

Council of Science Editors:

Haji Ruslan KN. PROTEIN HYDROGELS AS TISSUE ENGINEERING SCAFFOLDS. [Doctoral Dissertation]. University of Manchester; 2015. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:262195

16. Craddock, Russell. Structural characterisation of aggrecan in cartilaginous tissues and tissue engineered constructs.

Degree: PhD, 2018, University of Manchester

 Collagen II and the proteoglycan aggrecan are key extracellular matrix (ECM) proteins in cartilaginous tissues such as the intervertebral disc (IVD). Given the functional role… (more)

Subjects/Keywords: Aggrecan; Protein characterisation; Atomic force microscopy; mechanics; tissue engineering

…List of Tables Table 1.1. Summary of intact aggrecan core protein contour length… …Engineering Society Annual Meeting, Manchester Metropolitan University, July 2017 Title… …Growth Factor NP iNP BCP BMP C CCP 1-Bromo-3-chloropropane Bone Morphogenic Protein Carbon… …Complement Regulatory Protein PBS PCR PSR SECMALS CLD COL CS CsCl ECM C-type Lectin Domain… …chain length Keratin Sulfate Lower Back Pain Core protein Length Glycosaminoglycan binding… 

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Craddock, R. (2018). Structural characterisation of aggrecan in cartilaginous tissues and tissue engineered constructs. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/structural-characterisation-of-aggrecan-in-cartilaginous-tissues-and-tissue-engineered-constructs(d1e72d1e-b0ac-4485-9a05-030a5faf8351).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.756905

Chicago Manual of Style (16th Edition):

Craddock, Russell. “Structural characterisation of aggrecan in cartilaginous tissues and tissue engineered constructs.” 2018. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. https://www.research.manchester.ac.uk/portal/en/theses/structural-characterisation-of-aggrecan-in-cartilaginous-tissues-and-tissue-engineered-constructs(d1e72d1e-b0ac-4485-9a05-030a5faf8351).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.756905.

MLA Handbook (7th Edition):

Craddock, Russell. “Structural characterisation of aggrecan in cartilaginous tissues and tissue engineered constructs.” 2018. Web. 07 Jul 2020.

Vancouver:

Craddock R. Structural characterisation of aggrecan in cartilaginous tissues and tissue engineered constructs. [Internet] [Doctoral dissertation]. University of Manchester; 2018. [cited 2020 Jul 07]. Available from: https://www.research.manchester.ac.uk/portal/en/theses/structural-characterisation-of-aggrecan-in-cartilaginous-tissues-and-tissue-engineered-constructs(d1e72d1e-b0ac-4485-9a05-030a5faf8351).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.756905.

Council of Science Editors:

Craddock R. Structural characterisation of aggrecan in cartilaginous tissues and tissue engineered constructs. [Doctoral Dissertation]. University of Manchester; 2018. Available from: https://www.research.manchester.ac.uk/portal/en/theses/structural-characterisation-of-aggrecan-in-cartilaginous-tissues-and-tissue-engineered-constructs(d1e72d1e-b0ac-4485-9a05-030a5faf8351).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.756905

17. Haji Ruslan, Khairunnisa Nabilah. Protein hydrogels as tissue engineering scaffolds.

Degree: PhD, 2015, University of Manchester

 Hydrogels aim to mimic the natural living environment by entrapping large amount of water or biological fluids in their polymeric network. There has been growing… (more)

Subjects/Keywords: 610.28; Hydrogels, Protein Hydrogels, HEWL, HEWL-PNIPAAm, Tissue Engineering, Scaffolds

Protein Hydrogels as Tissue Engineering Scaffolds”, submitted by Khairunnisa Nabilah Haji Ruslan… …engineering scaffolds. It also considers the formation of protein hydrogels in terms of the gelation… …molecules and the interior of protein patches. 2.3.2.2 Lysozyme hydrogels as a tissue engineering… …30 Figure 2.8 Possible routes to protein-polymer conjugation… …Figure 3.5 Schematic representing the click approach to polymer-protein bioconjugate.... 39… 

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Haji Ruslan, K. N. (2015). Protein hydrogels as tissue engineering scaffolds. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/protein-hydrogels-as-tissue-engineering-scaffolds(45ff4e72-49ea-46df-9e7b-b9113576c096).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.647403

Chicago Manual of Style (16th Edition):

Haji Ruslan, Khairunnisa Nabilah. “Protein hydrogels as tissue engineering scaffolds.” 2015. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. https://www.research.manchester.ac.uk/portal/en/theses/protein-hydrogels-as-tissue-engineering-scaffolds(45ff4e72-49ea-46df-9e7b-b9113576c096).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.647403.

MLA Handbook (7th Edition):

Haji Ruslan, Khairunnisa Nabilah. “Protein hydrogels as tissue engineering scaffolds.” 2015. Web. 07 Jul 2020.

Vancouver:

Haji Ruslan KN. Protein hydrogels as tissue engineering scaffolds. [Internet] [Doctoral dissertation]. University of Manchester; 2015. [cited 2020 Jul 07]. Available from: https://www.research.manchester.ac.uk/portal/en/theses/protein-hydrogels-as-tissue-engineering-scaffolds(45ff4e72-49ea-46df-9e7b-b9113576c096).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.647403.

Council of Science Editors:

Haji Ruslan KN. Protein hydrogels as tissue engineering scaffolds. [Doctoral Dissertation]. University of Manchester; 2015. Available from: https://www.research.manchester.ac.uk/portal/en/theses/protein-hydrogels-as-tissue-engineering-scaffolds(45ff4e72-49ea-46df-9e7b-b9113576c096).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.647403


University of Manchester

18. Jeffreys, Laura. High-value oxy-pharmaceuticals from P450 BM3 'gatekeeper' mutations.

Degree: PhD, 2019, University of Manchester

 P450 BM3 is a natural fusion protein containing a heme catalytic domain fused to a CPR-like domain that binds two flavin cofactors (FAD and FMN).… (more)

Subjects/Keywords: FDA metabolites; Drug screening; Fibrates; Anti-diabetics; Azoles; Synthetic biology; Protein engineering; FDA-approved; Cytochrome P450; P450 BM3; HDX-MS; Metabolite turnover

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Jeffreys, L. (2019). High-value oxy-pharmaceuticals from P450 BM3 'gatekeeper' mutations. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/highvalue-oxypharmaceuticals-from-p450-bm3-agatekeepera-mutations(882d8dd6-195a-44e4-bacd-2fb7bda8d917).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.799455

Chicago Manual of Style (16th Edition):

Jeffreys, Laura. “High-value oxy-pharmaceuticals from P450 BM3 'gatekeeper' mutations.” 2019. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. https://www.research.manchester.ac.uk/portal/en/theses/highvalue-oxypharmaceuticals-from-p450-bm3-agatekeepera-mutations(882d8dd6-195a-44e4-bacd-2fb7bda8d917).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.799455.

MLA Handbook (7th Edition):

Jeffreys, Laura. “High-value oxy-pharmaceuticals from P450 BM3 'gatekeeper' mutations.” 2019. Web. 07 Jul 2020.

Vancouver:

Jeffreys L. High-value oxy-pharmaceuticals from P450 BM3 'gatekeeper' mutations. [Internet] [Doctoral dissertation]. University of Manchester; 2019. [cited 2020 Jul 07]. Available from: https://www.research.manchester.ac.uk/portal/en/theses/highvalue-oxypharmaceuticals-from-p450-bm3-agatekeepera-mutations(882d8dd6-195a-44e4-bacd-2fb7bda8d917).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.799455.

Council of Science Editors:

Jeffreys L. High-value oxy-pharmaceuticals from P450 BM3 'gatekeeper' mutations. [Doctoral Dissertation]. University of Manchester; 2019. Available from: https://www.research.manchester.ac.uk/portal/en/theses/highvalue-oxypharmaceuticals-from-p450-bm3-agatekeepera-mutations(882d8dd6-195a-44e4-bacd-2fb7bda8d917).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.799455


University of Manchester

19. Jeffreys, Laura. High-value oxy-pharmaceuticals from P450 BM3 ‘gatekeeper’ mutations.

Degree: 2019, University of Manchester

 P450 BM3 is a natural fusion protein containing a heme catalytic domain fused to a CPR-like domain that binds two flavin cofactors (FAD and FMN).… (more)

Subjects/Keywords: P450 BM3; Cytochrome P450; FDA-approved; Protein engineering; Synthetic biology; FDA metabolites; Azoles; Anti-diabetics; Fibrates; Drug screening; HDX-MS; Metabolite turnover

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Jeffreys, L. (2019). High-value oxy-pharmaceuticals from P450 BM3 ‘gatekeeper’ mutations. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:318548

Chicago Manual of Style (16th Edition):

Jeffreys, Laura. “High-value oxy-pharmaceuticals from P450 BM3 ‘gatekeeper’ mutations.” 2019. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:318548.

MLA Handbook (7th Edition):

Jeffreys, Laura. “High-value oxy-pharmaceuticals from P450 BM3 ‘gatekeeper’ mutations.” 2019. Web. 07 Jul 2020.

Vancouver:

Jeffreys L. High-value oxy-pharmaceuticals from P450 BM3 ‘gatekeeper’ mutations. [Internet] [Doctoral dissertation]. University of Manchester; 2019. [cited 2020 Jul 07]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:318548.

Council of Science Editors:

Jeffreys L. High-value oxy-pharmaceuticals from P450 BM3 ‘gatekeeper’ mutations. [Doctoral Dissertation]. University of Manchester; 2019. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:318548

20. Aleku, Godwin. Development of imine reductases and reductive aminases for chiral amine synthesis.

Degree: PhD, 2017, University of Manchester

 Novel biocatalysts for the enantioselective reduction of imines and reductive amination of a broad range of carbonyl compounds have been developed. Unlike other imine reductases… (more)

Subjects/Keywords: 540; imine reductases; reductive aminases; biocatalysis; biotransformation; protein engineering; catalysis; kinetic resolution

…achieved in the field of protein engineering. Several methods of laboratory evolution of enzymes… …quicker to fit enzymes to industrial processes through protein engineering.10 Rational… …simultaneous advances in biocatalysis, protein engineering and high-throughput screening technologies… …application of protein engineering has enabled the development of even more efficient and robust… …regard and protein engineering efforts have demonstrated that biocatalysts can further be… 

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Aleku, G. (2017). Development of imine reductases and reductive aminases for chiral amine synthesis. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/development-of-imine-reductases-and-reductive-aminases-for-chiral-amine-synthesis(6ba24d6a-3f09-467f-aa46-75fc77e142ea).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740315

Chicago Manual of Style (16th Edition):

Aleku, Godwin. “Development of imine reductases and reductive aminases for chiral amine synthesis.” 2017. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. https://www.research.manchester.ac.uk/portal/en/theses/development-of-imine-reductases-and-reductive-aminases-for-chiral-amine-synthesis(6ba24d6a-3f09-467f-aa46-75fc77e142ea).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740315.

MLA Handbook (7th Edition):

Aleku, Godwin. “Development of imine reductases and reductive aminases for chiral amine synthesis.” 2017. Web. 07 Jul 2020.

Vancouver:

Aleku G. Development of imine reductases and reductive aminases for chiral amine synthesis. [Internet] [Doctoral dissertation]. University of Manchester; 2017. [cited 2020 Jul 07]. Available from: https://www.research.manchester.ac.uk/portal/en/theses/development-of-imine-reductases-and-reductive-aminases-for-chiral-amine-synthesis(6ba24d6a-3f09-467f-aa46-75fc77e142ea).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740315.

Council of Science Editors:

Aleku G. Development of imine reductases and reductive aminases for chiral amine synthesis. [Doctoral Dissertation]. University of Manchester; 2017. Available from: https://www.research.manchester.ac.uk/portal/en/theses/development-of-imine-reductases-and-reductive-aminases-for-chiral-amine-synthesis(6ba24d6a-3f09-467f-aa46-75fc77e142ea).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.740315

21. Ashworth, Mark. Structure-Based Engineering of CYP105AS1 for the Production of High-Value Molecules.

Degree: 2018, University of Manchester

 Biocatalysis represents an attractive route to the production of various compounds which are difficult or impossible to synthesise and isolate using traditional chemical synthesis. In… (more)

Subjects/Keywords: Synthetic biology; Protein engineering; Enzyme engineering; Computational enzyme design; Biocatalysis; Enantioselectivity; Biotechnology; Statins; Pravastatin; Cytochrome P450; CYP105AS1

…molecular engineering progress has greatly expanded the toolbox of the practicing protein engineer… …engineering capability. Protein evolution by techniques such as gene shuffling (Stemmer, 1994… …compounded by insufficient fidelity in protein engineering approaches), necessitated… …2002). With the powerful protein engineering tools now available, this paradigm has… …197 4.4.5 Instability of the Putative P450prava-RhFRed Fusion Protein… 

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Ashworth, M. (2018). Structure-Based Engineering of CYP105AS1 for the Production of High-Value Molecules. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:313068

Chicago Manual of Style (16th Edition):

Ashworth, Mark. “Structure-Based Engineering of CYP105AS1 for the Production of High-Value Molecules.” 2018. Doctoral Dissertation, University of Manchester. Accessed July 07, 2020. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:313068.

MLA Handbook (7th Edition):

Ashworth, Mark. “Structure-Based Engineering of CYP105AS1 for the Production of High-Value Molecules.” 2018. Web. 07 Jul 2020.

Vancouver:

Ashworth M. Structure-Based Engineering of CYP105AS1 for the Production of High-Value Molecules. [Internet] [Doctoral dissertation]. University of Manchester; 2018. [cited 2020 Jul 07]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:313068.

Council of Science Editors:

Ashworth M. Structure-Based Engineering of CYP105AS1 for the Production of High-Value Molecules. [Doctoral Dissertation]. University of Manchester; 2018. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:313068

.