You searched for subject:(Propri t s des cosyst mes)
.
Showing records 1 – 30 of
40163 total matches.
◁ [1] [2] [3] [4] [5] … [1339] ▶

University of Georgia
1.
Morrell, Geoff.
Language of the non-speaking: structure as biophilic voice and source of hope in T.S. Eliot’s The waste land.
Degree: MA, English, 2007, University of Georgia
URL: http://purl.galileo.usg.edu/uga_etd/morrell_geoff_m_200712_ma
► The fact that T. S. Eliot’s The Waste Land presents an ecologically and culturally destitute world would appear to make the poem an obvious focus…
(more)
▼ The fact that
T.
S. Eliot’
s The Waste Land presents an ecologically and culturally destitute world would appear to make the poem an obvious focus of attention for ecocritics, especially given our current growing environmental problems. This has not been the case, however. I argue that by using the principles of ecology and biophilia, it becomes possible to read the structure of The Waste Land as being a voice in and of itself, a long neglected voice that speaks to the potential redemption of civilization through the recognition of the integral interconnectedness of all things. The structure of The Waste Land is a very intricate web of fragments that mimic the interconnections that form a healthy ecosystem. This structure is in direct contrast to the emptiness and desolation of the poem’
s content, reflecting the effects that human conceit has on civilization when a civilization regards itself as being separate from the rest of the natural world.
Advisors/Committee Members: Carl Rapp.
Subjects/Keywords: T. S. Eliot
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Morrell, G. (2007). Language of the non-speaking: structure as biophilic voice and source of hope in T.S. Eliot’s The waste land. (Masters Thesis). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/morrell_geoff_m_200712_ma
Chicago Manual of Style (16th Edition):
Morrell, Geoff. “Language of the non-speaking: structure as biophilic voice and source of hope in T.S. Eliot’s The waste land.” 2007. Masters Thesis, University of Georgia. Accessed December 07, 2019.
http://purl.galileo.usg.edu/uga_etd/morrell_geoff_m_200712_ma.
MLA Handbook (7th Edition):
Morrell, Geoff. “Language of the non-speaking: structure as biophilic voice and source of hope in T.S. Eliot’s The waste land.” 2007. Web. 07 Dec 2019.
Vancouver:
Morrell G. Language of the non-speaking: structure as biophilic voice and source of hope in T.S. Eliot’s The waste land. [Internet] [Masters thesis]. University of Georgia; 2007. [cited 2019 Dec 07].
Available from: http://purl.galileo.usg.edu/uga_etd/morrell_geoff_m_200712_ma.
Council of Science Editors:
Morrell G. Language of the non-speaking: structure as biophilic voice and source of hope in T.S. Eliot’s The waste land. [Masters Thesis]. University of Georgia; 2007. Available from: http://purl.galileo.usg.edu/uga_etd/morrell_geoff_m_200712_ma
2.
Héritier, Laurent.
Changements environnementaux et menaces sur la biodiversité des écosystèmes aquatiques : Environmental changes and threats on freshwater ecosystems and biodiversity.
Degree: Docteur es, Biologie, 2016, Perpignan
URL: http://www.theses.fr/2016PERP0034
► L’empreinte humaine sur Terre est si profonde qu’elle entraine des changements environnementaux qui affectent et modifient le fonctionnement des écosystèmes. Parmi tous les biotopes, les…
(more)
▼ L’empreinte humaine sur Terre est si profonde qu’elle entraine des changements environnementaux qui affectent et modifient le fonctionnement des écosystèmes. Parmi tous les biotopes, les écosystèmes aquatiques continentaux sont des habitats remarquables qui abritent une grande biodiversité, mais qui sont aussi les plus menacés par les activitéshumaines. Les principales causes de la perte de qualité de l'eau et de la perturbation des ces écosystèmes comprennent la pollution des eaux et l'introduction d'espèces exotiques. La partie première partie de ce travail de thèse a montré des invasions parasitaires sur les populations de tortues d'eau douce indigènes, transmis par des espèces de tortues introduites. De plus, la nécessité d'étudier et de décrire les nouvelles espèces de parasites invasives avec des techniques plus performantes a été soulignée. La deuxième partie de cette thèse a consisté en l'élaboration d'un outil pour évaluer l'état de la santé des populations de tortues d'eau douce sauvages, ce qui reflète également le niveau de contamination des cours d'eau.
Human imprint on Earth is actually so profound leading global environmental changes that affects and modifies the functioning of ecosystems. Among the natural biomes, freshwater ecosystems are remarkable habitats that comprise great species biodiversity but are also the most threatened by human activities. The main causes of the loss of water quality anddisruption of freshwater ecosystems includes water pollution and the introduction of alien species. The fisrt part of this thesis showed invasion of parasites on native freshwater turtle populations, carried by introduced turtle species. Furthermore, it highlighted the necessary to study and describe the new invasive parasite species with more performant technics. The second part of this thesis consisted in the development of a tool to evaluate the status of thehealth of wild freshwater turtle populations, allowed also the level of contamination of the watercourses.
Advisors/Committee Members: Verneau, Olivier (thesis director), Meistertzheim, Anne-Leila (thesis director), Du Preez, Louis (thesis director).
Subjects/Keywords: Invasions biologiques; Pollution des eaux; Glyphosate; E. orbicularis; M. leprosa; T. s. elegans; Biological invasions; Water pollution; 570
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Héritier, L. (2016). Changements environnementaux et menaces sur la biodiversité des écosystèmes aquatiques : Environmental changes and threats on freshwater ecosystems and biodiversity. (Doctoral Dissertation). Perpignan. Retrieved from http://www.theses.fr/2016PERP0034
Chicago Manual of Style (16th Edition):
Héritier, Laurent. “Changements environnementaux et menaces sur la biodiversité des écosystèmes aquatiques : Environmental changes and threats on freshwater ecosystems and biodiversity.” 2016. Doctoral Dissertation, Perpignan. Accessed December 07, 2019.
http://www.theses.fr/2016PERP0034.
MLA Handbook (7th Edition):
Héritier, Laurent. “Changements environnementaux et menaces sur la biodiversité des écosystèmes aquatiques : Environmental changes and threats on freshwater ecosystems and biodiversity.” 2016. Web. 07 Dec 2019.
Vancouver:
Héritier L. Changements environnementaux et menaces sur la biodiversité des écosystèmes aquatiques : Environmental changes and threats on freshwater ecosystems and biodiversity. [Internet] [Doctoral dissertation]. Perpignan; 2016. [cited 2019 Dec 07].
Available from: http://www.theses.fr/2016PERP0034.
Council of Science Editors:
Héritier L. Changements environnementaux et menaces sur la biodiversité des écosystèmes aquatiques : Environmental changes and threats on freshwater ecosystems and biodiversity. [Doctoral Dissertation]. Perpignan; 2016. Available from: http://www.theses.fr/2016PERP0034

Cornell University
3.
Mihara, Yoshiaki.
Reading T. S. Eliot Reading Spinoza
.
Degree: 2013, Cornell University
URL: http://hdl.handle.net/1813/33962
► "[The ordinary man] falls in love, or reads Spinoza, and these two experiences have nothing to do with each other" - a good reader of…
(more)
▼ "[The ordinary man] falls in love, or reads Spinoza, and these two experiences have nothing to do with each other" - a good reader of
T.
S. Eliot'
s criticism probably knows this famous passage; a good researcher on Eliot'
s apprenticeship in philosophy perhaps knows that he did actually read Spinoza; and yet, in the current Eliot studies, reading Eliot and reading Spinoza seem to have nothing to do with each other. In this dissertation, I attempt to reconstruct Eliot'
s reading of Spinoza as faithfully and comprehensively as possible, by closely analyzing the marginalia in Eliot'
s copy of Spinoza'
s Opera, housed in the Archive Centre of King'
s College, Cambridge. At the same time, the Spinozist context for Eliot'
s apprenticeship at Harvard and Oxford (with the intermission of "a romantic year" in Paris) is also to be presented, which is, in fact, a glaring absence in the philosophical branch of Eliot studies. In addition to these positivistic contributions, I also take a theoretical approach so as to demonstrate how illuminative Eliot'
s reading of Spinoza can be for understanding the characteristic style (or "ethology") of Eliot'
s reading in general (i.e., Theory), by way of extensively analyzing the unpublished as well as published materials of Eliot'
s "academic philosophizing" that culminated in his doctoral dissertation on F. H. Bradley. Furthermore, theories of reading are to be provided mainly by the (New) Spinozist tradition, e.g., Deleuzean "double reading" and Althusserian "symptomatic reading". With these theoretical weapons in hand, I examine the ways in which Eliot'
s repression, or symptomatic oversights, of the Ontological question in his "systematic reading" of Spinoza (hence his Theory in general) is dogged by the return of the repressed "affective reading", while his evasion of the Ontological question leads to an epistemological deadlock over the issue of solipsism, which is only to be resolved, rather violently, by a "leap" at an imagined commonality based on "essential kinship" that Eliot has contrived for himself - in sharp contrast to the idea of an "inessential commonality" that Agamben derives from Spinozian "common notions". Finally, the political afterlives of Eliot'
s Theory are problematized through the analysis of several uncanny mis/readings, or appropriations, of Eliot'
s celebrated essay, "Tradition and the Individual Talent". Those politicized mis/readings by Nishida Kitarō (arguably the greatest philosopher of Imperial Japan) and Ch'oe Chaesŏ (a most prominent "pro-Japanese" intellectual in Colonial Korea) as well as that by the later Eliot himself will, in turn, illuminate the idea of Empire and its logic that are latent in Eliot'
s ostensibly "purely literary" theory of "Tradition".
Advisors/Committee Members: Melas, Natalie Anne-Marie (committeeMember), Waite, Geoffrey Carter W (committeeMember), Mao, Douglas (committeeMember), Sakai, Naoki (committeeMember).
Subjects/Keywords: T. S. Eliot;
Spinoza;
Empire
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mihara, Y. (2013). Reading T. S. Eliot Reading Spinoza
. (Thesis). Cornell University. Retrieved from http://hdl.handle.net/1813/33962
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Mihara, Yoshiaki. “Reading T. S. Eliot Reading Spinoza
.” 2013. Thesis, Cornell University. Accessed December 07, 2019.
http://hdl.handle.net/1813/33962.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Mihara, Yoshiaki. “Reading T. S. Eliot Reading Spinoza
.” 2013. Web. 07 Dec 2019.
Vancouver:
Mihara Y. Reading T. S. Eliot Reading Spinoza
. [Internet] [Thesis]. Cornell University; 2013. [cited 2019 Dec 07].
Available from: http://hdl.handle.net/1813/33962.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Mihara Y. Reading T. S. Eliot Reading Spinoza
. [Thesis]. Cornell University; 2013. Available from: http://hdl.handle.net/1813/33962
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
4.
Ben Khedher, Anis.
Amélioration de la qualité des données produits échangées entre l'ingénierie et la production à travers l'intégration de systèmes d'information dédiés : Quality Improvement of product data exchanged between engineering and production through the integration of dedicated information systems.
Degree: Docteur es, Informatique, 2012, Université Lumière – Lyon II
URL: http://www.theses.fr/2012LYO20012
► Le travail présenté dans ce mémoire de thèse apporte sa contribution à l'amélioration de la qualité des données échangées entre la production et les services…
(more)
▼ Le travail présenté dans ce mémoire de thèse apporte sa contribution à l'amélioration de la qualité des données échangées entre la production et les services d'ingénierie dédiés à la conception du produit et du système de production associé. Cette amélioration de la qualité des données passe par l'étude des interactions entre la gestion du cycle de vie du produit et la gestion de la production.Ces deux concepts étant supportés, tout ou partie, par des systèmes d'information industriels, l'étude de leurs interactions a ensuite conduit à l'intégration de ces systèmes d'information (PLM, ERP et MES). Dans un contexte de forte concurrence et de mondialisation, les entreprises sont obligées d'innover et de minimiser les coûts, notamment ceux de production. Face à ces enjeux, le volume des données de production et leur fréquence de modification ne cessent d'augmenter en raison de la réduction constante de la durée de vie et de mise sur le marché des produits, de la personnalisation accrue des produits et en n de la généralisation des démarches d'amélioration continue en production. La conséquence directe est alors la nécessité de formaliser et de gérer l'ensemble des données de production devant être fournies aux opérateurs de production et aux machines. Suite à une analyse du point de vue de la qualité des données pour chaque architecture existante démontrant ainsi leur incapacité à répondre à cette problématique, une architecture basée sur l'intégration des trois systèmes d'information directement impliqués dans la production (PLM, ERP et MES) a été proposée. Cette architecture nous a menés à deux sous-problématiques complémentaires qui sont respectivement la construction d'une architecture basée sur des Web Services permettant d'améliorer l'accessibilité, la sécurité et la complétude des données échangées, et la construction d'une architecture d'intégration, basée sur les ontologies, permettant d'offrir des mécanismes d'intégration basés sur la sémantique dans le but d'assurer la bonne interprétation des données échangées.Enfin, la maquette de l'outil logiciel supportant la solution proposée et permettant d'assurer l'intégration des données échangées entre ingénierie et production a été réalisée.
The research work contributes to improve the quality of data exchanged between the production and the engineering units which dedicated to product design and production system design. This improvement is qualified by studying the interactions between the product life cycle management and the production management. These two concepts are supported, wholly or partly by industrial information systems, the study of the interactions then lead to the integration of information systems (PLM, ERP and MES).In a highly competitive environment and globalization, companies are forced to innovate and reduce costs, especially the production costs. Facing with these challenges, the volume and frequency change of production data are increasing due to the steady reduction of the lifetime and the products marketing, the increasing of product…
Advisors/Committee Members: Bouras, Abdelaziz (thesis director).
Subjects/Keywords: Qualité des données; Ingénierie; Production; Système d'information industriel; PLM; ERP; MES; Intégration; Ontologies; Web services; Data Quality; Engineering; Production; Industrial Information System; PLM; ERP; MES; Integration; Ontologies; Web services
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ben Khedher, A. (2012). Amélioration de la qualité des données produits échangées entre l'ingénierie et la production à travers l'intégration de systèmes d'information dédiés : Quality Improvement of product data exchanged between engineering and production through the integration of dedicated information systems. (Doctoral Dissertation). Université Lumière – Lyon II. Retrieved from http://www.theses.fr/2012LYO20012
Chicago Manual of Style (16th Edition):
Ben Khedher, Anis. “Amélioration de la qualité des données produits échangées entre l'ingénierie et la production à travers l'intégration de systèmes d'information dédiés : Quality Improvement of product data exchanged between engineering and production through the integration of dedicated information systems.” 2012. Doctoral Dissertation, Université Lumière – Lyon II. Accessed December 07, 2019.
http://www.theses.fr/2012LYO20012.
MLA Handbook (7th Edition):
Ben Khedher, Anis. “Amélioration de la qualité des données produits échangées entre l'ingénierie et la production à travers l'intégration de systèmes d'information dédiés : Quality Improvement of product data exchanged between engineering and production through the integration of dedicated information systems.” 2012. Web. 07 Dec 2019.
Vancouver:
Ben Khedher A. Amélioration de la qualité des données produits échangées entre l'ingénierie et la production à travers l'intégration de systèmes d'information dédiés : Quality Improvement of product data exchanged between engineering and production through the integration of dedicated information systems. [Internet] [Doctoral dissertation]. Université Lumière – Lyon II; 2012. [cited 2019 Dec 07].
Available from: http://www.theses.fr/2012LYO20012.
Council of Science Editors:
Ben Khedher A. Amélioration de la qualité des données produits échangées entre l'ingénierie et la production à travers l'intégration de systèmes d'information dédiés : Quality Improvement of product data exchanged between engineering and production through the integration of dedicated information systems. [Doctoral Dissertation]. Université Lumière – Lyon II; 2012. Available from: http://www.theses.fr/2012LYO20012
5.
Oluwafisoye, Opeyemi.
Business Ethics and Corporate Social Responsibility” THE PERCEPTION OF EMPLOYEES ON BUSINESS ETHICS IN AN ORGANIZATION.
Degree: 2013, , School of Management
URL: http://urn.kb.se/resolve?urn=urn:nbn:se:bth-3743
► Global organizations are fast-changing in technological, legal, economic, social, and political structures with competing stakeholders as well as power claims. They are embedded in…
(more)
▼ Global organizations are fast-changing in technological, legal, economic, social, and political structures with competing stakeholders as well as power claims. They are embedded in and interact with multiple changing local, national, and international environments. These environments call for business ethics in many situations for proper interrelation and interactions among businesses and economies. Organizations are starting to adopt ethics programs as a response to the negative publicity associated with interactions with different environments. Maintaining public trust is essential for organizations to receive continued support from suppliers, customers, as well as other stakeholders. Ethics plays an important role in the development of a strategic plan. However, understandably stakeholders are naturally pre-occupied with profitability often completely disregarding the role of ethics and corporate social responsibility, considering the fact that companies in a bid to render agreed returns to their stakeholders are mostly concerned with marketing campaigns and sales advertisement and all other antics to dislodge competitors and meet assigned budget targets. Therefore, it is essential to examine the perceptions of employees on business ethics within the organization in order to properly develop ethics programs. This study attempts to examine the relationship of business ethics with the position, years of experience, and gender in order to develop some ethics program which can match the perceptions of employees on ethics.
+1 773 733 6415; +234 812 246 6674
Subjects/Keywords: M; A; S; T; E; R
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Oluwafisoye, O. (2013). Business Ethics and Corporate Social Responsibility” THE PERCEPTION OF EMPLOYEES ON BUSINESS ETHICS IN AN ORGANIZATION. (Thesis). , School of Management. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:bth-3743
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Oluwafisoye, Opeyemi. “Business Ethics and Corporate Social Responsibility” THE PERCEPTION OF EMPLOYEES ON BUSINESS ETHICS IN AN ORGANIZATION.” 2013. Thesis, , School of Management. Accessed December 07, 2019.
http://urn.kb.se/resolve?urn=urn:nbn:se:bth-3743.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Oluwafisoye, Opeyemi. “Business Ethics and Corporate Social Responsibility” THE PERCEPTION OF EMPLOYEES ON BUSINESS ETHICS IN AN ORGANIZATION.” 2013. Web. 07 Dec 2019.
Vancouver:
Oluwafisoye O. Business Ethics and Corporate Social Responsibility” THE PERCEPTION OF EMPLOYEES ON BUSINESS ETHICS IN AN ORGANIZATION. [Internet] [Thesis]. , School of Management; 2013. [cited 2019 Dec 07].
Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:bth-3743.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Oluwafisoye O. Business Ethics and Corporate Social Responsibility” THE PERCEPTION OF EMPLOYEES ON BUSINESS ETHICS IN AN ORGANIZATION. [Thesis]. , School of Management; 2013. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:bth-3743
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade Presbiteriana Mackenzie
6.
Tania de Fátima da Silva.
A intertextualidade do mito pagão e cristâo em The Waste Land, de T. S. Eliot.
Degree: 2006, Universidade Presbiteriana Mackenzie
URL: http://tede.mackenzie.com.br//tde_busca/arquivo.php?codArquivo=95
► This work aims at analysing the Anglo-American poet and essayist Thomas Stearns Eliots use of intertextuality in his poem The Waste Land, published in 1922.Our…
(more)
▼ This work aims at analysing the Anglo-American poet and essayist Thomas Stearns Eliots use of intertextuality in his poem The Waste Land, published in 1922.Our analysis focuses on myth and its function within the poem. We have chosen four myths, three of them Pagan (Sibila, Tiresias and The Fisher King) and one Christian (The Holy Grail). The latter has a deep relationship to The Fisher King myth. We will mention theoretical concepts referring to intertextuality and myth and will present a survey of the poem as a whole. We will also report form briefly on the political-social situation of Europe at the time in which the poem was written, and the poets main achievements in his career. Our next focus will be the analysis of the above mentioned myths as well as their function and relevance within the context of the poem.
O presente trabalho tem por objetivo analisar a intertextualidade no poema The Waste Land, do poeta e ensaísta anglo-americano Thomas Stearns Eliot, publicado em 1922. Focaliza o mito e sua função dentro do poema. Foram escolhidos particularmente quatro mitos, três pagãos (Sibila, Tirésias e Rei Pescador) e um cristão (Santo Graal), sendo que este último tem uma relação estreita com o mito do Rei Pescador. Examinar-se-ão postulados teóricos sobre o mito, a intertextualidade e a situação político-social da Europa, na época em que Eliot compôs o poema, bem como da trajetória do poeta.
Advisors/Committee Members: Elaine Cristina Prado dos Santos, Lílian Lopondo.
Subjects/Keywords: LITERATURA COMPARADA; mito; intertextualidade; T. S. Eliot; myth; intertextuality; T. S. Eliot
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Silva, T. d. F. d. (2006). A intertextualidade do mito pagão e cristâo em The Waste Land, de T. S. Eliot. (Thesis). Universidade Presbiteriana Mackenzie. Retrieved from http://tede.mackenzie.com.br//tde_busca/arquivo.php?codArquivo=95
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Silva, Tania de Fátima da. “A intertextualidade do mito pagão e cristâo em The Waste Land, de T. S. Eliot.” 2006. Thesis, Universidade Presbiteriana Mackenzie. Accessed December 07, 2019.
http://tede.mackenzie.com.br//tde_busca/arquivo.php?codArquivo=95.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Silva, Tania de Fátima da. “A intertextualidade do mito pagão e cristâo em The Waste Land, de T. S. Eliot.” 2006. Web. 07 Dec 2019.
Vancouver:
Silva TdFd. A intertextualidade do mito pagão e cristâo em The Waste Land, de T. S. Eliot. [Internet] [Thesis]. Universidade Presbiteriana Mackenzie; 2006. [cited 2019 Dec 07].
Available from: http://tede.mackenzie.com.br//tde_busca/arquivo.php?codArquivo=95.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Silva TdFd. A intertextualidade do mito pagão e cristâo em The Waste Land, de T. S. Eliot. [Thesis]. Universidade Presbiteriana Mackenzie; 2006. Available from: http://tede.mackenzie.com.br//tde_busca/arquivo.php?codArquivo=95
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Kaunas University of Medicine
7.
Ražanauskaitė,
Rūta.
S-E-T koncepcija pagrįstos kineziterapijos
efektyvumas pacientams, turintiems juosmens tarpslankstelinio disko
išvaržą.
Degree: Master, Nursing, 2009, Kaunas University of Medicine
URL: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2009~D_20090617_163318-30372
;
► Tyrimo tikslas: įvertinti S-E-T koncepcija pagrįstos kineziterapijos efektyvumą gydant pacientus, turinčius juosmens tarpslankstelinio disko išvaržą. Tyrimo uždaviniai: 1.) įvertinti tiriamosios ir kontrolinės grupės pacientų griaučių-raumenų…
(more)
▼ Tyrimo tikslas: įvertinti S-E-T koncepcija
pagrįstos kineziterapijos efektyvumą gydant pacientus, turinčius
juosmens tarpslankstelinio disko išvaržą. Tyrimo uždaviniai: 1.)
įvertinti tiriamosios ir kontrolinės grupės pacientų
griaučių-raumenų sistemos funkcinę būklę prieš ir po gydymo; 2.)
atlikti tiriamosios ir kontrolinės grupės pacientų kompleksinę
skausmo analizę prieš ir po gydymo; 3.) nustatyti tiriamosios ir
kontrolinės grupės pacientų negalios lygį prieš ir po gydymo; 4.)
apibendrinti ir palyginti gautus tyrimo duomenis įvertinant S-E-T
koncepcija pagrįstos kineziterapijos efektyvumą. Tyrimo metodai:
Tyrime dalyvavo 30 pacientų, kuriems buvo diagnozuota juosmens
tarpslankstelinio disko išvarža. Visi tiriamieji buvo suskirstyti į
tiriamąją (20 pacientų) ir kontrolę (10 pacientų) grupes.
Tiriamosios grupės pacientai, atsižvelgiant į skausmo lokalizaciją,
buvo suskirstyti į du pogrupius, kurių kiekviename buvo po 10
pacientų. Visiems pacientams buvo atlikta po 14 individualių
kineziterapijos procedūrų. Gydymo pradžioje ir po gydymo visiems
pacientams buvo vertinama funkcinė būklė, atliekama kompleksinė
skausmo analizė ir nustatomas negalios lygis. Išvados: 1.) A. Po
kineziterapijos pagal S-E-T koncepciją stebėtas nervo jautrumo
sumažėjimas, judesių amplitudės, atlikties judesių, siekimo su
apkrova ir pilvo raumenų ištvermės pagerėjimas (p<0,05). B. Po
įprastinės kineziterapijos pagerėjo tik abipusio šoninio lenkimo
judesių amplitudė (p<0,05). 2.) A. Po kienziterpaijos... [toliau
žr. visą tekstą]
The purpose of the work: to evaluate
efficiency of physiotherapy, based on S-E-T concept, for patients
with lumbar intervertebral disc herniation. Goals: 1.) to evaluate
the functional state of patients of test and control groups before
and after treatment; 2.) to accomplish the comprehensive analysis
of the pain of patients of test and control groups before and after
treatment; 3.) to determine the disability level of patients of
test and control groups before and after treatment; 4.) to
summarize and compare the received data of study in justice to
efficiency of the physiotherapy based on S-E-T concept. Methods:
Study included 30 patients with lumbar intevertebral disc
herniation. All the test were divided into intervention group (20
patients) and control group (10 patients). The patients of
intervention group depending on location of pain were divided into
two subgroups. It was performed 14 procedures of individual
physiotherapy for all patients. At the beginning and the end of
treatment the functional condition was evaluated, the comprehensive
analysis of the pain was accomplished and the level of disability
was determined for all patients. Conclusions: 1.) A. After
physiotherapy according to S-E-T concept noticed the reduction of
nerve sensitivity, improvement of range of motion, movements of
performance, reaching towards with load and abdominal muscle static
strength (p<0,05). B. After the usual physiotherapy improved
only bilateral bending range of motion (p<0,05). 2.)... [to full
text]
Advisors/Committee Members: Zaveckas, Vidmantas (Master’s thesis supervisor), Šakalienė, Rasa (Master’s thesis reviewer), Kimtys, Algimantas (Master’s degree committee member), Rimdeikienė, Inesa (Master’s degree committee member), Šakalienė, Rasa (Master’s degree committee member), Milinavičienė, Eglė (Master’s degree committee member), Vainoras, Alfonsas (Master’s degree committee member), Kriščiūnas, Aleksandras (Master’s degree committee chair).
Subjects/Keywords: S-E-T
koncepcija; Dinaminė
stabilizacija; Trakcija; S-E-T concept; Dynamic
stabilization; Traction
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ražanauskaitė,
Rūta. (2009). S-E-T koncepcija pagrįstos kineziterapijos
efektyvumas pacientams, turintiems juosmens tarpslankstelinio disko
išvaržą. (Masters Thesis). Kaunas University of Medicine. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2009~D_20090617_163318-30372 ;
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Chicago Manual of Style (16th Edition):
Ražanauskaitė,
Rūta. “S-E-T koncepcija pagrįstos kineziterapijos
efektyvumas pacientams, turintiems juosmens tarpslankstelinio disko
išvaržą.” 2009. Masters Thesis, Kaunas University of Medicine. Accessed December 07, 2019.
http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2009~D_20090617_163318-30372 ;.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
MLA Handbook (7th Edition):
Ražanauskaitė,
Rūta. “S-E-T koncepcija pagrįstos kineziterapijos
efektyvumas pacientams, turintiems juosmens tarpslankstelinio disko
išvaržą.” 2009. Web. 07 Dec 2019.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Vancouver:
Ražanauskaitė,
Rūta. S-E-T koncepcija pagrįstos kineziterapijos
efektyvumas pacientams, turintiems juosmens tarpslankstelinio disko
išvaržą. [Internet] [Masters thesis]. Kaunas University of Medicine; 2009. [cited 2019 Dec 07].
Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2009~D_20090617_163318-30372 ;.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Council of Science Editors:
Ražanauskaitė,
Rūta. S-E-T koncepcija pagrįstos kineziterapijos
efektyvumas pacientams, turintiems juosmens tarpslankstelinio disko
išvaržą. [Masters Thesis]. Kaunas University of Medicine; 2009. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2009~D_20090617_163318-30372 ;
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
8.
Younis, Vincent.
Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius.
Degree: Care and Social Welfare, 2017, Mälardalen University
URL: http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412
► Studien undersöker invånare och verksammas upplevelser av ett, enligt en rapport frånunderrättelseenheten, utsatt bostadsområde i Västerås. För att besvara frågeställningen har vigenomfört 14 intervjuer…
(more)
▼ Studien undersöker invånare och verksammas upplevelser av ett, enligt en rapport frånunderrättelseenheten, utsatt bostadsområde i Västerås. För att besvara frågeställningen har vigenomfört 14 intervjuer varav 5 var semistrukturerade och resterande var ostrukturerade. Vihar även genomfört 6 observationer, där samtliga var icke deltagande observationer. Dåmålsättningen var att undersöka så förutsättningslöst som möjligt har vi använt oss av BarneyGlasers variant av grundad teori som metodologiskt angreppssätt. Tidigare forskning som vibelyser är delade i tre teman: Segregation, familjestrukturer och sysselsättning. En teorisom är grundad i data presenteras i resultatdelen och beskriver det som sker i Bäckby.Studiens teoretiska referensramar är Erving Goffmans teori om stigma, Howard. S. Beckersteori om avvikande samt Giorgio Agambens teori om undantag och belägring som fungerarsom en komplettering till förståelsen av hur det är i ett utsatt bostadsområde. Slutsatsernavisar att det är en handfull ungdomar som står för oron som sker i Bäckby och dess handlingarmöjliggörs på grund av misslyckade strukturella åtgärder. De förhållanden vi har funnitavgörande för trygghets upplevelse i Bäckby är inte endast att ungdomar behöversysselsättning, utan det behövs även en spridning av människor med utländsk bakgrund blandetniska svenskar och förebyggande åtgärder från externa aktörer.
Subjects/Keywords: u n g d o m a r; b o s t a d s o m r å d e; s y s s e l s ä t t n i n g; s p r i d n i n g; b r o t t; t r y g g h e t; Social Sciences; Samhällsvetenskap
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Younis, V. (2017). Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius. (Thesis). Mälardalen University. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Younis, Vincent. “Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius.” 2017. Thesis, Mälardalen University. Accessed December 07, 2019.
http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Younis, Vincent. “Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius.” 2017. Web. 07 Dec 2019.
Vancouver:
Younis V. Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius. [Internet] [Thesis]. Mälardalen University; 2017. [cited 2019 Dec 07].
Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Younis V. Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius. [Thesis]. Mälardalen University; 2017. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

NSYSU
9.
Chang, Hsiang-Chih.
Utilizing Theory of Constraints to Improve the Implementation of Manufacturing Executive Systemï¼A Case Study for T Company.
Degree: Master, Information Management, 2018, NSYSU
URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0316118-170838
► Manufacturing Exective Systems (MES) has been developed for many years. Enterprises think that can improve the efficiency of production operations by implementation MES and then…
(more)
▼ Manufacturing Exective Systems (
MES) has been developed for many years. Enterprises think that can improve the efficiency of production operations by implementation
MES and then seek outsourced resources for implementation. Previously, case studies pointed out that each enterprise culture is different and faces varied problems in system implementation among them, people problem is the biggest especially. Theory of constraint creator Goldratt mentioned the goal of factory is to make money, the effective output can make companies continue to profitability, whether the effective output depends on the bottleneck, if the existing operating processes before the implementation of new system has not changed, it will not improve the performance of factory operations, and make it less competitive. After introducing the system into the factory, the senior manager can not feel the benefits after the introduction. The reason is that there is a new bottleneck. Therefore, this study explores the process by which a case company implement into the manufacturing execution system by using the theory of constraint tool to find out the system restrictions, to find out the main reasons for the situation, but these problems are not unsolvable, but because of conflicts and obstacles, still need to consider the hidden risks. In this study, past case information is provided to improve the case. The method of implementation is not perfect, but suitable. The research reference to the relevant literature, the inductive case company research results are as follows, to provide a reference for the future enterprise implement system:
(A) Human error can only be reduced, but can not be avoided, mode of operation should be changed.
(B) Outsourcing choose industry-experienced software vendors, after the ability to consider its own development.
(C) Before the introduction of enterprises to establish internal
MES system awareness, manufacturers should learn the relevant industry knowledge.
(D) To formulate short-term and long-term measures to reduce the dependence on the old system.
Advisors/Committee Members: Jen-Jsung Huang (chair), Pin-Yang Liu (committee member), William S. Chao (chair).
Subjects/Keywords: TOC; MES; CSF
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Chang, H. (2018). Utilizing Theory of Constraints to Improve the Implementation of Manufacturing Executive Systemï¼A Case Study for T Company. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0316118-170838
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Chang, Hsiang-Chih. “Utilizing Theory of Constraints to Improve the Implementation of Manufacturing Executive Systemï¼A Case Study for T Company.” 2018. Thesis, NSYSU. Accessed December 07, 2019.
http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0316118-170838.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Chang, Hsiang-Chih. “Utilizing Theory of Constraints to Improve the Implementation of Manufacturing Executive Systemï¼A Case Study for T Company.” 2018. Web. 07 Dec 2019.
Vancouver:
Chang H. Utilizing Theory of Constraints to Improve the Implementation of Manufacturing Executive Systemï¼A Case Study for T Company. [Internet] [Thesis]. NSYSU; 2018. [cited 2019 Dec 07].
Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0316118-170838.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Chang H. Utilizing Theory of Constraints to Improve the Implementation of Manufacturing Executive Systemï¼A Case Study for T Company. [Thesis]. NSYSU; 2018. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0316118-170838
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
10.
Benoit, Sylvain.
Three Essays on Systemic Risk : Trois essais sur le risque systémique.
Degree: Docteur es, Sciences économiques, 2014, Université d'Orléans
URL: http://www.theses.fr/2014ORLE0508
► Le risque systémique a joué un rôle clé dans la propagation de la dernière crise financière mondiale.Un grand nombre de mesures de ce risque ont…
(more)
▼ Le risque systémique a joué un rôle clé dans la propagation de la dernière crise financière mondiale.Un grand nombre de mesures de ce risque ont été développées pour évaluer la contribution d’une institutionfinancière au risque de l’ensemble du système. Toutefois, de nombreuses questions concernantles capacités de ces mesures à identifier les institutions financières d’importance systémique (SIFIs) ontété soulevées puisque le risque systémique possède de multiples facettes et certaines d’entre elles sontdifficiles identifier, telles que les similitudes entre institutions financières.L’objectif général de cette thèse en finance est donc (i) de proposer une solution empirique pour identifierles SIFIs au niveau nationale, (ii) de comparer théoriquement et empiriquement différentes mesures durisque systémique et (iii) de mesurer les changements d’expositions au risque des banques.Tout d’abord, le chapitre 1 propose un ajustement de trois mesures de risque systémique basées sur desdonnées de marchés et conçues dans un cadre international, afin d’identifier les SIFIs au niveau national.Ensuite, le chapitre 2 introduit un modèle commun dans lequel plusieurs mesures du risque systémiquesont exprimées et comparées. Il y est théoriquement établi que ces mesures de risque systémique peuventêtre exprimées en fonction de mesures traditionnelles de risque. L’application empirique confirme cesrésultats et montre que ces mesures ne sont pas capables de saisir la nature multidimensionnelle durisque systémique. Enfin, le chapitre 3 présente la méthodologie appelée Factor Implied Risk Exposures(FIRE) permettant de décomposer une variation de la mesure de risque d’une banque en deux éléments,le premier représentant la volatilité de marché et le second correspondant à l’exposition au risque de labanque. Ce chapitre illustre empiriquement que les changements d’expositions au risque sont corréléspositivement entre les banques, ce qui est cohérent avec le fait que les banques présentent des similitudesdans leurs prises de positions sur le marché.
Systemic risk has played a key role in the propagation of the last global financial crisis. A large number ofsystemic risk measures have been developed to quantify the contribution of a financial institution to thesystem-wide risk. However, numerous questions about their abilities to identify Systemically ImportantFinancial Institutions (SIFIs) have been raised since systemic risk has multiple facets, and some of themare difficult to gauge, such as the commonalities across financial institutions.The main goal of this dissertation in finance is thus (i) to propose an empirical solution to identifydomestic SIFIs, (ii) to compare theoretically and empirically different systemic risk measures, and (iii)to measure changes in banks’ risk exposures.First, chapter 1 offers an adjustment of three market-based systemic risk measures, designed in a globalframework, to identify domestic SIFIs. Second, chapter 2 introduces a common framework in whichseveral systemic risk measures are expressed and compared.…
Advisors/Committee Members: Hurlin, Christophe (thesis director), Pérignon, Christophe (thesis director).
Subjects/Keywords: Risque systémique; Régulation bancaire; Institutions financières d’importance systémique; MES; SRISK; CoVaR; Divulgation des risqueDisclosures; VaR; Capital Réglementaire; Systemic Risk; Banking Regulation; Systemically Important Financial Institutions,; MES; SRISK; CoVaR; Risk Disclosure; VaR; Regulatory Capital; 330
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Benoit, S. (2014). Three Essays on Systemic Risk : Trois essais sur le risque systémique. (Doctoral Dissertation). Université d'Orléans. Retrieved from http://www.theses.fr/2014ORLE0508
Chicago Manual of Style (16th Edition):
Benoit, Sylvain. “Three Essays on Systemic Risk : Trois essais sur le risque systémique.” 2014. Doctoral Dissertation, Université d'Orléans. Accessed December 07, 2019.
http://www.theses.fr/2014ORLE0508.
MLA Handbook (7th Edition):
Benoit, Sylvain. “Three Essays on Systemic Risk : Trois essais sur le risque systémique.” 2014. Web. 07 Dec 2019.
Vancouver:
Benoit S. Three Essays on Systemic Risk : Trois essais sur le risque systémique. [Internet] [Doctoral dissertation]. Université d'Orléans; 2014. [cited 2019 Dec 07].
Available from: http://www.theses.fr/2014ORLE0508.
Council of Science Editors:
Benoit S. Three Essays on Systemic Risk : Trois essais sur le risque systémique. [Doctoral Dissertation]. Université d'Orléans; 2014. Available from: http://www.theses.fr/2014ORLE0508

Université de Montréal
11.
Leignadier, Julie.
Étude de l’implication de la force du signal transmis par le récepteur des cellules T dans le développement et la survie des lymphocytes T mémoires
.
Degree: 2010, Université de Montréal
URL: http://hdl.handle.net/1866/4140
► Suite à la rencontre d’un antigène (Ag) présenté à la surface des cellules présentatrice de l’Ag (CPA), les lymphocytes T naïfs, ayant un récepteur des…
(more)
▼ Suite à la rencontre d’un antigène (Ag) présenté à la surface
des cellules présentatrice de l’Ag (CPA), les lymphocytes
T naïfs, ayant un récepteur
des cellules
T (RCT) spécifique de l’Ag, vont proliférer et se différencier en LT effecteurs (1). Suite à l’élimination de l’Ag la majorité
des LTe vont mourir par apoptose alors que les restants vont se différencier en LT mémoire (LTm) protégeant l’organisme à long terme. Les mécanismes qui permettent la différenciation
des LTe en LTm sont encore inconnus.
Pour comprendre comment les LTm CD8+ sont généré
s à partir
des LTe, nous avons émis l’hypothèse que la densité de l’Ag présenté par les CPA peut avoir un impact sur la sélection
des LT CD8+ répondant l’Ag à se différencier en LTm. De manière intéressante, nos résultats montrent qu’une immunisation avec
des cellules dendritiques (DCs) exprimant un haut niveau de complexe CMH/peptide à sa surface permet le développement de LTm. À l’inverse, le développement
des LTm est fortement réduit (10-20X) lorsque les souris sont immunisées avec
des DCs exprimant un niveau faible de complexes CMH/peptide à leur surface. De plus, la quantité d’Ag n’a aucune influence ni sur l’expansion
des LT CD8+ ni sur l’acquisition de leurs fonctions effectrices, mais affecte de manière critique la génération
des LTm. Nos résultats suggèrent que le nombre de RCT engagé lors de la reconnaissance de l’Ag est important pour la formation
des LTm. Pour cela nous avons observé par vidéo-microscopie le temps d’interaction entre
des LTn et
des DCs. Nos résultats montrent que le temps et la qualité de l’interaction sont dépendants de la densité d’Ag présenté par les DCs. Effectivement, nous observons une diminution dans le pourcentage de LT faisant une interaction prolongée avec les DCs quand le niveau d’Ag est faible. De plus, nous observons
des variations de l’expression
des facteurs de transcription clefs impliqué
s dans la différenciation
des LTm tels qu’Eomes, Bcl-6 et Blimp-1. Par ailleurs, la densité d’Ag fait varier l’expression du Neuron-derived orphan nuclear receptor 1 (Nor-1). Nor-1 est impliqué dans la conversion de Bcl-2 en molécule pro-apoptotique et contribue à la mort par apoptose
des LTe pendant la phase de contraction. Notre modèle propose que la densité de l’épitope contrôle la génération
des CD8+ LTm. Une meilleure compréhension
des mécanismes impliqué
s dans la génération
des LTm permettra le développement de meilleures stratégies pour la génération de vaccin.
Dans un second temps, nous avons évalué le rôle du signal RCT dans l’homéostasie
des LTm. Pour ce faire, nous avons utilisé un modèle de souris transgénique pour le RCT dont son expression peut être modulée par un traitement à la tétracycline. Ce système nous a permis d’abolir l’expression du RCT à la surface
des LTm. De manière intéressante, en absence de RCT exprimé, les LTm CD8+ peuvent survivre à long terme dans l’organisme et rester fonctionnels. De plus, une sous population
des LTm CD4+ a la capacité de survivre sans RCT exprimé dans un hôte lymphopénique alors que…
Advisors/Committee Members: Labrecque, Nathalie (advisor).
Subjects/Keywords: Lymphocyte T;
Récepteur spécifique des cellules T;
Mémoire immunologique;
Densité d’antigène;
T lymphocyte;
T cell receptor;
Immunological memory;
Density of antigen
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Leignadier, J. (2010). Étude de l’implication de la force du signal transmis par le récepteur des cellules T dans le développement et la survie des lymphocytes T mémoires
. (Thesis). Université de Montréal. Retrieved from http://hdl.handle.net/1866/4140
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Leignadier, Julie. “Étude de l’implication de la force du signal transmis par le récepteur des cellules T dans le développement et la survie des lymphocytes T mémoires
.” 2010. Thesis, Université de Montréal. Accessed December 07, 2019.
http://hdl.handle.net/1866/4140.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Leignadier, Julie. “Étude de l’implication de la force du signal transmis par le récepteur des cellules T dans le développement et la survie des lymphocytes T mémoires
.” 2010. Web. 07 Dec 2019.
Vancouver:
Leignadier J. Étude de l’implication de la force du signal transmis par le récepteur des cellules T dans le développement et la survie des lymphocytes T mémoires
. [Internet] [Thesis]. Université de Montréal; 2010. [cited 2019 Dec 07].
Available from: http://hdl.handle.net/1866/4140.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Leignadier J. Étude de l’implication de la force du signal transmis par le récepteur des cellules T dans le développement et la survie des lymphocytes T mémoires
. [Thesis]. Université de Montréal; 2010. Available from: http://hdl.handle.net/1866/4140
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade de Brasília
12.
Nancy Aparecida Campos Nuniz.
O CNPq e sua trajetória de planejamento e gestão em C&T: histórias para não dormir, contadas pelos seus técnicos (1975-1995).
Degree: 2008, Universidade de Brasília
URL: http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4437
► O objeto de estudo desta tese é a construção da história do planejamento em ciência e tecnologia no CNPq, a partir das representações de seus…
(more)
▼ O objeto de estudo desta tese é a construção da história do planejamento em ciência e tecnologia no CNPq, a partir das representações de seus técnicos, no período compreendido entre 1975-1995. A pesquisa tem por objetivo analisar as representações dos técnicos do CNPq, enquanto formuladores de políticas públicas de ciência e tecnologia, mediante a construção de uma história do planejamento da instituição que a partir de 1974 passa por momentos de inflexão. O estudo se desenvolve através da construção de dois cenários históricos constituídos a partir dos períodos 1975-84, período da ditadura militar e 1985-95, período dos governos civis. Através da comparação entre os cenários, a trajetória do técnico em planejamento do CNPq foi sendo reconstruída, iluminando a história do campo de C&T no Brasil que se entremeia com a história do próprio CNPq. O delineamento dessa trajetória permite a identificação das transformações ocorridas nas representações da importância das atividades de planejamento no setor de C&T bem como nas representações dos técnicos sobre si mesmos e sobre o próprio CNPq. Foram realizadas trinta entrevistas com os sujeitos, a partir da metodologia de história oral que possibilitou a emergência dos seguintes subtemas da pesquisa: tecnocracia, CNPq e comunidade cientifica, espírito de corpo, liberdade de expressão, status e competência técnica, e saber técnico institucional. Assim, a pesquisa procurou identificar as representações dos técnicos segundo as temáticas mais exploradas nas falas, expressas nos subtemas, por meio da análise de discurso. Através do enfoque da história cultural, procuramos demonstrar como uma rede de significados vai sendo construída e desconstruída através da força performática dos discursos governamentais e institucionais, estabelecendo inscrições e apagamentos. Com ancoragem na história do tempo presente e na história cultural, nosso referencial teórico principal é constituído a partir de diálogos com Roger Chartier, Pierre Bourdieu, Le Goff, De Certeau e Castoriadis.
The objective of this thesis is to study the construction of the history of planning in science and technology in CNPq, from the representations of its technicians in the period between 1975 and 1995. The research aims to analyze the representations of CNPq technicians, as formulators of public policies in science and technology, in the face of the construction of a history of planning at the institution which starts going through moments of inflection in 1974. Being based on the history of the present time and also on cultural history, our main theoretical reference is made from dialogues with Roger Chartier, Bourdieu, Le Goff, De Certeau and Castoriadis. The study is developed through the construction of two historical scenarios made up of the periods 1975-84, a period of military dictatorship and 1985-95, a period of civilian governments. By comparing the scenarios, the trajectory of the technician in planning at the CNPq has been being rebuilt, lighting the history of the field of science and technology in…
Advisors/Committee Members: Marcia de Melo Martins Kuyumjian, Ronaldo Conde Aguiar, Fernando Antônio Faria, Francisco Fernando Monteoliva Doratioto, Ubiratan D Ambrósio.
Subjects/Keywords: C&T; técnico; planejamento; representações; HISTORIA; CNPq; technician; planning; representations; CNPq; S&T
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Nuniz, N. A. C. (2008). O CNPq e sua trajetória de planejamento e gestão em C&T: histórias para não dormir, contadas pelos seus técnicos (1975-1995). (Thesis). Universidade de Brasília. Retrieved from http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4437
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Nuniz, Nancy Aparecida Campos. “O CNPq e sua trajetória de planejamento e gestão em C&T: histórias para não dormir, contadas pelos seus técnicos (1975-1995).” 2008. Thesis, Universidade de Brasília. Accessed December 07, 2019.
http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4437.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Nuniz, Nancy Aparecida Campos. “O CNPq e sua trajetória de planejamento e gestão em C&T: histórias para não dormir, contadas pelos seus técnicos (1975-1995).” 2008. Web. 07 Dec 2019.
Vancouver:
Nuniz NAC. O CNPq e sua trajetória de planejamento e gestão em C&T: histórias para não dormir, contadas pelos seus técnicos (1975-1995). [Internet] [Thesis]. Universidade de Brasília; 2008. [cited 2019 Dec 07].
Available from: http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4437.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Nuniz NAC. O CNPq e sua trajetória de planejamento e gestão em C&T: histórias para não dormir, contadas pelos seus técnicos (1975-1995). [Thesis]. Universidade de Brasília; 2008. Available from: http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4437
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
13.
Santos, Tanila Wood dos.
Análise da resposta celular induzida no pulmão pela imunização de camundongos com vacinas pneumocócicas híbridas PspA-PLY.
Degree: Mestrado, Biotecnologia, 2014, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/87/87131/tde-10122014-103341/
;
► Streptococcus pneumoniae é responsável por milhões de mortes anuais no mundo todo. As vacinas atuais são baseadas em polissacarídeos capsulares e apresentam cobertura limitada. Assim,…
(more)
▼ Streptococcus pneumoniae é responsável por milhões de mortes anuais no mundo todo. As vacinas atuais são baseadas em polissacarídeos capsulares e apresentam cobertura limitada. Assim, diversas proteínas tem sido estudadas como alternativas vacinais, dentre as quais se destacam PspA e PLY. Os objetivos deste estudo foram caracterizar produção de anticorpos e a resposta celular induzida pela imunização com vacinas híbridas PspA-PLY em modelo de pneumonia. Os anticorpos apresentaram elevada capacidade de ligação a pneumococos expressando PspAs de família 2, bem como um aumento na deposição de complemento nestes isolados. A imunização com as proteínas híbridas protegeu os camundongos do desafio sistêmico com pneumococo contendo PspA de família 2. Foi desenvolvido um modelo de pneumonia lobar em camundongos, onde a imunização com PspA-PLY induziu um aumento de IL-6 e TNF nos pulmões após o desafio, levando a uma redução no número de bactérias nos pulmões dos animais. Os dados sugerem que a fusão de PspA à PLY é capaz de ampliar a cobertura protetora a isolados expressando PspAs distintas, e que essa mesma vacina á capaz de proteger os animais contra pneumonia, pela indução precoce de citocinas como IL-6 e TNF-a nos pulmões.
Streptococcus pneumoniae is responsible for millions of deaths annually around the globe. The current vaccines are based on capsular polysaccharides, and have limited coverage. Thus, several proteins have been investigated as alternative vaccines, including PspA and PLY. The present study aimed at characterizing the antibody production and cellular immune response induced by mouse immunization with PspA-PLY hybrid vaccines in a pneumonia model. The induced antibodies demonstrated a strong recognition of pneumococci expressing family 2 PspA molecules, as well as an enhancement in complement deposition in their surface. Immunization with the fusion protein protected mice from systemic challenge with a pneumococcal isolate bearing a family 2 PspA. A model of lobar pneumonia was developed in BALB/c mice, where the immunization with the PspA-PLY fusion induced an increase in IL-6 and TNF-a production in the lungs after pneumococcal challenge, leading to a reduction on bacteria load in the lungs of immunized mice. The data suggests that fusion of PspA to PLY is capable of increasing vaccine coverage aginst pneumococcal infection with isolates bearing family 2 PspAs, and confer protection in mice against pneumonia, by the early production of IL-6 and TNF-a in the lungs.
Advisors/Committee Members: Bertoncini, Michelle Darrieux Sampaio.
Subjects/Keywords: S. Pneumoniae; S. pneumoniae; Células T; Citocinas; Cytokines; Pneumococcus; Pneumococo; Pneumolisina; Pneumolysin; PspA; PspA; T cells
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Santos, T. W. d. (2014). Análise da resposta celular induzida no pulmão pela imunização de camundongos com vacinas pneumocócicas híbridas PspA-PLY. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/87/87131/tde-10122014-103341/ ;
Chicago Manual of Style (16th Edition):
Santos, Tanila Wood dos. “Análise da resposta celular induzida no pulmão pela imunização de camundongos com vacinas pneumocócicas híbridas PspA-PLY.” 2014. Masters Thesis, University of São Paulo. Accessed December 07, 2019.
http://www.teses.usp.br/teses/disponiveis/87/87131/tde-10122014-103341/ ;.
MLA Handbook (7th Edition):
Santos, Tanila Wood dos. “Análise da resposta celular induzida no pulmão pela imunização de camundongos com vacinas pneumocócicas híbridas PspA-PLY.” 2014. Web. 07 Dec 2019.
Vancouver:
Santos TWd. Análise da resposta celular induzida no pulmão pela imunização de camundongos com vacinas pneumocócicas híbridas PspA-PLY. [Internet] [Masters thesis]. University of São Paulo; 2014. [cited 2019 Dec 07].
Available from: http://www.teses.usp.br/teses/disponiveis/87/87131/tde-10122014-103341/ ;.
Council of Science Editors:
Santos TWd. Análise da resposta celular induzida no pulmão pela imunização de camundongos com vacinas pneumocócicas híbridas PspA-PLY. [Masters Thesis]. University of São Paulo; 2014. Available from: http://www.teses.usp.br/teses/disponiveis/87/87131/tde-10122014-103341/ ;

Universidade do Rio Grande do Norte
14.
Asth, Laila da Silva.
Avaliação dos efeitos do biperideno, diazepam e neuropeptídeos S sobre a memória e a ansiedade na tarefa do labirinto em T elevado em camundongos
.
Degree: 2012, Universidade do Rio Grande do Norte
URL: http://repositorio.ufrn.br/handle/123456789/17330
► Anxiety is an emotional phenomenon, and normally it is interpreted as an adaptative behavior front to adversities. In its pathological form, anxiety can severely affect…
(more)
▼ Anxiety is an emotional phenomenon, and normally it is interpreted as an adaptative behavior front to adversities. In its pathological form, anxiety can severely affect aspects related to the personal and professional life. Studies have shown a close relationship between anxiety disorders and aversive
memory processing. Considering that the pharmacotherapy of anxiety disorders is still limited, innovative anxiolytic agents are needed. In this regard, neuropeptides systems are interesting therapeutic targets to the treatment of psychopathologies. Neuropeptide
S (NPS), a 20-aminoacid peptide, is the
endogenous ligand of a G-protein coupled receptor (NPSR), which has been reported to evoke hyperlocomotion, awakefull states, besides anxiolysis and memory improvements in rodents. This study aimed to investigate the effects of biperiden (BPR; an amnesic drug), diazepam (DZP; an anxiolytic drug) and
NPS at three distinct times: pre-training, post-training, and pre-test, in order to assess anxiety and memory process in the same animal model. The elevated Tmaze (ETM) is an apparatus derived from the elevated plus-maze test, which consists of one enclosed and two open arms. The procedure is based on the
avoidance of open spaces learned during training session, in which mice were exposed to the enclosed arm as many times as needed to stay 300
s. In the test session, memory is assessed by re-exposing the mouse to the enclosed arm and the latency to enter an open arm was recorded. When injected pre-training,
BPR (1 mg/kg) impaired learning and memory processing; DZP (1 and 2 mg/kg) evoked anxiolysis, but only at the dose of 2 mg/kg impaired memory; and NPS 0.1 nmol induced anxiolysis without affecting memory. Post-training injection of DZP (2 mg/kg) or BPR (1 and 3 mg/kg) did not affect memory consolidation,
while the post-trainning administration of NPS 1 nmol, but not 0.1 nmol, improved memory in mice. Indeed, pre-trainning administration of NPS 1 nmol did not prevent memory impairment elicited by BPR (2 mg/kg, injected before training). In the open field test, BPR 1 mg/kg and NPS 1 nmol induced hyperlocomotion in mice. In conclusion, the proposed ETM task is practical for
the detection of the anxiolytic and amnesic effects of drugs. The anxiolytic and memory enhancement effects of NPS were detected in the ETM task, and reinforce the role of NPS system as an interesting therapeutic target to the treatment of anxiety disorders
Advisors/Committee Members: Gavioli, Elaine Cristina (advisor), CPF:97013390968 (advisor).
Subjects/Keywords: Ansiedade;
Memória;
Neuropeptídeo S;
Labirinto em T
elevado;
Camundongo;
Anxiety;
Memory;
Neuropeptide S;
Elevated T maze;
Mouse
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Asth, L. d. S. (2012). Avaliação dos efeitos do biperideno, diazepam e neuropeptídeos S sobre a memória e a ansiedade na tarefa do labirinto em T elevado em camundongos
. (Masters Thesis). Universidade do Rio Grande do Norte. Retrieved from http://repositorio.ufrn.br/handle/123456789/17330
Chicago Manual of Style (16th Edition):
Asth, Laila da Silva. “Avaliação dos efeitos do biperideno, diazepam e neuropeptídeos S sobre a memória e a ansiedade na tarefa do labirinto em T elevado em camundongos
.” 2012. Masters Thesis, Universidade do Rio Grande do Norte. Accessed December 07, 2019.
http://repositorio.ufrn.br/handle/123456789/17330.
MLA Handbook (7th Edition):
Asth, Laila da Silva. “Avaliação dos efeitos do biperideno, diazepam e neuropeptídeos S sobre a memória e a ansiedade na tarefa do labirinto em T elevado em camundongos
.” 2012. Web. 07 Dec 2019.
Vancouver:
Asth LdS. Avaliação dos efeitos do biperideno, diazepam e neuropeptídeos S sobre a memória e a ansiedade na tarefa do labirinto em T elevado em camundongos
. [Internet] [Masters thesis]. Universidade do Rio Grande do Norte; 2012. [cited 2019 Dec 07].
Available from: http://repositorio.ufrn.br/handle/123456789/17330.
Council of Science Editors:
Asth LdS. Avaliação dos efeitos do biperideno, diazepam e neuropeptídeos S sobre a memória e a ansiedade na tarefa do labirinto em T elevado em camundongos
. [Masters Thesis]. Universidade do Rio Grande do Norte; 2012. Available from: http://repositorio.ufrn.br/handle/123456789/17330

Universidade do Rio Grande do Norte
15.
Asth, Laila da Silva.
Avaliação dos efeitos do biperideno, diazepam e neuropeptídeos S sobre a memória e a ansiedade na tarefa do labirinto em T elevado em camundongos
.
Degree: 2012, Universidade do Rio Grande do Norte
URL: http://repositorio.ufrn.br/handle/123456789/17330
► Anxiety is an emotional phenomenon, and normally it is interpreted as an adaptative behavior front to adversities. In its pathological form, anxiety can severely affect…
(more)
▼ Anxiety is an emotional phenomenon, and normally it is interpreted as an adaptative behavior front to adversities. In its pathological form, anxiety can severely affect aspects related to the personal and professional life. Studies have shown a close relationship between anxiety disorders and aversive
memory processing. Considering that the pharmacotherapy of anxiety disorders is still limited, innovative anxiolytic agents are needed. In this regard, neuropeptides systems are interesting therapeutic targets to the treatment of psychopathologies. Neuropeptide
S (NPS), a 20-aminoacid peptide, is the
endogenous ligand of a G-protein coupled receptor (NPSR), which has been reported to evoke hyperlocomotion, awakefull states, besides anxiolysis and memory improvements in rodents. This study aimed to investigate the effects of biperiden (BPR; an amnesic drug), diazepam (DZP; an anxiolytic drug) and
NPS at three distinct times: pre-training, post-training, and pre-test, in order to assess anxiety and memory process in the same animal model. The elevated Tmaze (ETM) is an apparatus derived from the elevated plus-maze test, which consists of one enclosed and two open arms. The procedure is based on the
avoidance of open spaces learned during training session, in which mice were exposed to the enclosed arm as many times as needed to stay 300
s. In the test session, memory is assessed by re-exposing the mouse to the enclosed arm and the latency to enter an open arm was recorded. When injected pre-training,
BPR (1 mg/kg) impaired learning and memory processing; DZP (1 and 2 mg/kg) evoked anxiolysis, but only at the dose of 2 mg/kg impaired memory; and NPS 0.1 nmol induced anxiolysis without affecting memory. Post-training injection of DZP (2 mg/kg) or BPR (1 and 3 mg/kg) did not affect memory consolidation,
while the post-trainning administration of NPS 1 nmol, but not 0.1 nmol, improved memory in mice. Indeed, pre-trainning administration of NPS 1 nmol did not prevent memory impairment elicited by BPR (2 mg/kg, injected before training). In the open field test, BPR 1 mg/kg and NPS 1 nmol induced hyperlocomotion in mice. In conclusion, the proposed ETM task is practical for
the detection of the anxiolytic and amnesic effects of drugs. The anxiolytic and memory enhancement effects of NPS were detected in the ETM task, and reinforce the role of NPS system as an interesting therapeutic target to the treatment of anxiety disorders
Advisors/Committee Members: Gavioli, Elaine Cristina (advisor), CPF:97013390968 (advisor).
Subjects/Keywords: Ansiedade;
Memória;
Neuropeptídeo S;
Labirinto em T
elevado;
Camundongo;
Anxiety;
Memory;
Neuropeptide S;
Elevated T maze;
Mouse
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Asth, L. d. S. (2012). Avaliação dos efeitos do biperideno, diazepam e neuropeptídeos S sobre a memória e a ansiedade na tarefa do labirinto em T elevado em camundongos
. (Thesis). Universidade do Rio Grande do Norte. Retrieved from http://repositorio.ufrn.br/handle/123456789/17330
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Asth, Laila da Silva. “Avaliação dos efeitos do biperideno, diazepam e neuropeptídeos S sobre a memória e a ansiedade na tarefa do labirinto em T elevado em camundongos
.” 2012. Thesis, Universidade do Rio Grande do Norte. Accessed December 07, 2019.
http://repositorio.ufrn.br/handle/123456789/17330.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Asth, Laila da Silva. “Avaliação dos efeitos do biperideno, diazepam e neuropeptídeos S sobre a memória e a ansiedade na tarefa do labirinto em T elevado em camundongos
.” 2012. Web. 07 Dec 2019.
Vancouver:
Asth LdS. Avaliação dos efeitos do biperideno, diazepam e neuropeptídeos S sobre a memória e a ansiedade na tarefa do labirinto em T elevado em camundongos
. [Internet] [Thesis]. Universidade do Rio Grande do Norte; 2012. [cited 2019 Dec 07].
Available from: http://repositorio.ufrn.br/handle/123456789/17330.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Asth LdS. Avaliação dos efeitos do biperideno, diazepam e neuropeptídeos S sobre a memória e a ansiedade na tarefa do labirinto em T elevado em camundongos
. [Thesis]. Universidade do Rio Grande do Norte; 2012. Available from: http://repositorio.ufrn.br/handle/123456789/17330
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
16.
Masi, Brice.
Identification de biomarqueurs de l'hépatopathie bilharzienne par imagerie de résonnance magnétique : Biomarkers identification of hepatosplenic schistosomiasis using magnetic resonance imaging.
Degree: Docteur es, Pathologie humaine. Maladies infectieuses, 2018, Aix Marseille Université
URL: http://www.theses.fr/2018AIXM0741
► Seconde affection parasitaire dans le monde derrière la malaria, la bilharziose ou schistosomiase demeure une maladie infectieuse tropicale négligée. L'espèce Schistosoma mansoni est la principale…
(more)
▼ Seconde affection parasitaire dans le monde derrière la malaria, la bilharziose ou schistosomiase demeure une maladie infectieuse tropicale négligée. L'espèce Schistosoma mansoni est la principale responsable de la forme digestive de la bilharziose humaine pouvant évoluer vers une pathologie chronique grave chez 5 à 10 % des individus infectés. Plusieurs années après l’infection, une fibrose hépatique importante se développe dans le foie et la paroi de l’intestin. La fibrose peut entraîner une hypertension portale et des varices gastro-oesophagiennes dont la rupture est potentiellement létale. Cette complication hépatosplénique est souvent associée à une hépatomégalie et une splénomégalie. L’objectif de ce travail était de fournir la première caractérisation longitudinale par IRM in vivo du modèle murin de schistosomiase digestive obtenu par infection de souris CBA/J avec Schistosoma mansoni. Le second objectif était la mise au point d’une technique quantitative ou semi-quantitative permettant d’évaluer la fibrose hépatique dans ce modèle. Nos données d’imagerie anatomique avec et sans agent de contraste (Gd-DOTA) et de relaxométrie (cartographies par mesure des temps de relaxation T2 et T2*) ont permis de confirmer les points communs entre le modèle murin de schistosomiase et la maladie humaine en termes d’organomégalie, d’inflammation granulomateuse, de fibrose et d’atteinte du système porte. Nos résultats suggèrent que le paramètre T2 pourrait être un biomarqueur non invasif et semi-quantitatif de la fibrose hépatique bilharzienne qui pourrait être utile dans le diagnostic et le suivi de la complication hépatosplénique et dans l’évaluation de nouvelles thérapies.
The second parasitic disease in the world behind malaria, bilharzia or schistosomiasis remains a neglected tropical infectious disease. Schistosoma mansoni is the main cause of the digestive form of human schistosomiasis that can progress to a severe chronic pathology in 5 to 10% of infected individuals. Several years after infection, significant hepatic fibrosis develops around parasite eggs in the liver and intestinal wall. Fibrosis can lead to portal hypertension and gastroesophageal varices, the rupture of which is potentially lethal. This hepato-splenic complication of digestive schistosomiasis is often associated with hepatomegaly and splenomegaly. The standard technique for the diagnosis of liver fibrosis is biopsy. The classical non-invasive evaluation of liver fibrosis is done by ultrasound imaging using an international classification scale (Niamey scale). Echography allows the assessment of portal hypertension by measuring the diameter of the portal vein and enables the detection of portal varices. The aim of this work was to provide the first in vivo longitudinal MRI characterization of the murine model of digestive schistosomiasis obtained by infection of CBA/J mice with Schistosoma mansoni. The second objective was to develop a quantitative or semi-quantitative method to evaluate liver fibrosis in this model. Our anatomical and volumetric…
Advisors/Committee Members: Viola, Angèle (thesis director), Bernard, Monique (thesis director).
Subjects/Keywords: Schistosomiase; S. mansoni; Organomégalie; Fibrose; Hépatique; Irm; Relaxométrie; T 2; Schistosomiasis; S. mansoni; Organomegaly; Fibrosis; Hepatic; Mri; Relaxometry; T 2
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Masi, B. (2018). Identification de biomarqueurs de l'hépatopathie bilharzienne par imagerie de résonnance magnétique : Biomarkers identification of hepatosplenic schistosomiasis using magnetic resonance imaging. (Doctoral Dissertation). Aix Marseille Université. Retrieved from http://www.theses.fr/2018AIXM0741
Chicago Manual of Style (16th Edition):
Masi, Brice. “Identification de biomarqueurs de l'hépatopathie bilharzienne par imagerie de résonnance magnétique : Biomarkers identification of hepatosplenic schistosomiasis using magnetic resonance imaging.” 2018. Doctoral Dissertation, Aix Marseille Université. Accessed December 07, 2019.
http://www.theses.fr/2018AIXM0741.
MLA Handbook (7th Edition):
Masi, Brice. “Identification de biomarqueurs de l'hépatopathie bilharzienne par imagerie de résonnance magnétique : Biomarkers identification of hepatosplenic schistosomiasis using magnetic resonance imaging.” 2018. Web. 07 Dec 2019.
Vancouver:
Masi B. Identification de biomarqueurs de l'hépatopathie bilharzienne par imagerie de résonnance magnétique : Biomarkers identification of hepatosplenic schistosomiasis using magnetic resonance imaging. [Internet] [Doctoral dissertation]. Aix Marseille Université 2018. [cited 2019 Dec 07].
Available from: http://www.theses.fr/2018AIXM0741.
Council of Science Editors:
Masi B. Identification de biomarqueurs de l'hépatopathie bilharzienne par imagerie de résonnance magnétique : Biomarkers identification of hepatosplenic schistosomiasis using magnetic resonance imaging. [Doctoral Dissertation]. Aix Marseille Université 2018. Available from: http://www.theses.fr/2018AIXM0741

Mahatma Gandhi University
17.
Cheriyan, Leena B.
The synergy of the Aesthetics of Rasa and Aucitya as
manifested in the drama of T S Eliot; -.
Degree: English Literature, 2013, Mahatma Gandhi University
URL: http://shodhganga.inflibnet.ac.in/handle/10603/7283
None
Bibliography p.253-268
Advisors/Committee Members: Abraham, M Y.
Subjects/Keywords: Aucitya; Rasa; T S Eliot
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Cheriyan, L. B. (2013). The synergy of the Aesthetics of Rasa and Aucitya as
manifested in the drama of T S Eliot; -. (Thesis). Mahatma Gandhi University. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/7283
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Cheriyan, Leena B. “The synergy of the Aesthetics of Rasa and Aucitya as
manifested in the drama of T S Eliot; -.” 2013. Thesis, Mahatma Gandhi University. Accessed December 07, 2019.
http://shodhganga.inflibnet.ac.in/handle/10603/7283.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Cheriyan, Leena B. “The synergy of the Aesthetics of Rasa and Aucitya as
manifested in the drama of T S Eliot; -.” 2013. Web. 07 Dec 2019.
Vancouver:
Cheriyan LB. The synergy of the Aesthetics of Rasa and Aucitya as
manifested in the drama of T S Eliot; -. [Internet] [Thesis]. Mahatma Gandhi University; 2013. [cited 2019 Dec 07].
Available from: http://shodhganga.inflibnet.ac.in/handle/10603/7283.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Cheriyan LB. The synergy of the Aesthetics of Rasa and Aucitya as
manifested in the drama of T S Eliot; -. [Thesis]. Mahatma Gandhi University; 2013. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/7283
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Georgia Tech
18.
Sun, Xiaojing.
The role of policy and markets in the development of the solar photovoltaic industry: Evidence from China.
Degree: PhD, Public Policy, 2016, Georgia Tech
URL: http://hdl.handle.net/1853/54948
► This dissertation looks at the technological innovation and market competitiveness of the solar PV industry in China, and examines the role played by policy and…
(more)
▼ This dissertation looks at the technological innovation and market competitiveness of the solar PV industry in China, and examines the role played by policy and markets in the development of the industry. Using solar cell lab efficiency and the quality and quantity of solar PV patents as indicators, this study finds that, unlike what conventional wisdom assumes, China is closing the innovation gap between itself and the world’
s leading innovators. This is mainly due to three reasons: a national strategic vision for innovation, growing public and private R&D investment, and an innovation ecosystem made of government sponsored science and technology programs and technology-specific global innovation networks. Solar PV manufacturing in China thrived on a fully-developed self-sufficient domestic supply chain that features a few highly concentrated industrial clusters, such as the one in the Yangtze River Delta area. The agglomeration economies it created, combined with economies of scale development, commercialization-oriented innovation, and attention to low-cost production are mainly responsible for the competitiveness of the solar PV manufacturing industry in China. However, weakness in tooling and material production due to a lack of advanced scientific knowledge and manufacturing skills constrains the further development of the supply chain. The emphasis on process innovation also renders the industry vulnerable to disruptive technologies.
Moving forward, policymakers should continue to promote global research networks and local production networks, and use innovation as a crosscutting lever to integrate R&D conducted in labs with innovation needed in the manufacturing sector and the supply chain.
Advisors/Committee Members: Brown, Marilyn (advisor), Clark, Jennifer (committee member), Wang, Fei-Ling (committee member), Matisoff, Daniel (committee member), Ball, Jeffrey (committee member).
Subjects/Keywords: Solar; Innovation; Manufacturing; Energy policy; S&T policy; Supply chain; Competitiveness
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Sun, X. (2016). The role of policy and markets in the development of the solar photovoltaic industry: Evidence from China. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/54948
Chicago Manual of Style (16th Edition):
Sun, Xiaojing. “The role of policy and markets in the development of the solar photovoltaic industry: Evidence from China.” 2016. Doctoral Dissertation, Georgia Tech. Accessed December 07, 2019.
http://hdl.handle.net/1853/54948.
MLA Handbook (7th Edition):
Sun, Xiaojing. “The role of policy and markets in the development of the solar photovoltaic industry: Evidence from China.” 2016. Web. 07 Dec 2019.
Vancouver:
Sun X. The role of policy and markets in the development of the solar photovoltaic industry: Evidence from China. [Internet] [Doctoral dissertation]. Georgia Tech; 2016. [cited 2019 Dec 07].
Available from: http://hdl.handle.net/1853/54948.
Council of Science Editors:
Sun X. The role of policy and markets in the development of the solar photovoltaic industry: Evidence from China. [Doctoral Dissertation]. Georgia Tech; 2016. Available from: http://hdl.handle.net/1853/54948

Ohio University
19.
Good, Ashley Clark.
Violent Eaters.
Degree: MA, English (Arts and Sciences), 2009, Ohio University
URL: http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1244214338
► This Thesis includes a collection of original poems with an introduction which attempts to explain some of the authors intent. Most of the poems convey…
(more)
▼ This Thesis includes a collection of original poems
with an introduction which attempts to explain some of the authors
intent. Most of the poems convey a sense of embarrassment through
unsure speakers. These speakers feel confused by the world they are
in and try to come to some understanding of what loneliness,
embarrassment, and stoic behaviors are worth. The moments where the
speaker is sure of himself are few and far between. The inheritance
of bad habits and melancholy are also examined in some of the
poems. All of these poems are about a search for art and love. The
Introduction attempts to show embarrassment in
T.
S. Eliot'
s work
as well as my own, pulling quotes from a book by Christopher Ricks
called, Keats and Embarrassment.
Advisors/Committee Members: Halliday, Mark (Committee Chair).
Subjects/Keywords: American Literature; Poetry; T. S. Eliot; Embarrassment; Music
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Good, A. C. (2009). Violent Eaters. (Masters Thesis). Ohio University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1244214338
Chicago Manual of Style (16th Edition):
Good, Ashley Clark. “Violent Eaters.” 2009. Masters Thesis, Ohio University. Accessed December 07, 2019.
http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1244214338.
MLA Handbook (7th Edition):
Good, Ashley Clark. “Violent Eaters.” 2009. Web. 07 Dec 2019.
Vancouver:
Good AC. Violent Eaters. [Internet] [Masters thesis]. Ohio University; 2009. [cited 2019 Dec 07].
Available from: http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1244214338.
Council of Science Editors:
Good AC. Violent Eaters. [Masters Thesis]. Ohio University; 2009. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1244214338

Massey University
20.
Kennedy, D. J.
A study of The Rock by T.S. Eliot.
Degree: MA, English, 1973, Massey University
URL: http://hdl.handle.net/10179/13874
► Chapter I of this thesis is just a brief account of the genesis of The Rock: brief for fear of reproducing what has already been…
(more)
▼ Chapter I of this thesis is just a brief account of the genesis of The Rock: brief for fear of reproducing what has already been ably said before by Mr E. Martin Browne in his book The Making of T.S. Eliot's Plays. In this section the pageant and music-hall revue, which were the vehicles for this vaguely propagandist work, are treated, and what is so strangely important about the music-hall form of entertainment is that Eliot was very much attracted to it. This chapter, although it just sets the scene, shows the author working at a much more superficial level than ever before. Chapter II deals with the importance of Eliot's socio-religious thinking relative to The Rock in the 1930s. The authoritarian nature and very rigour of his orthodoxy may have been partly the reason why The Rock and After Strange Gods were never republished, but the important point is made clear, through these views on Christian orthodoxy and tradition, that Eliot was to be admired as perhaps the only poet and intellectual of great standing in England in the 1930s who gave his allegiance to something wholly outside himself. In addition, what is made explicit in this chapter, and held implicit throughout, is that Eliot was no turncoat who now gladly and facilely embraced the succour of Mother Church as some critics would have us believe. What is made plain is that this relatively new convert was finding a via media between facile hope and pointless despair - hence the very discipline and rigour of his Anglo-Catholic affirmations. Chapter III is about the requirements of the medium in what was in fact the first time Eliot had moved beyond a coterie audience. The demands and limitations are listed as criteria against which The Rock can only be measured; and although the choruses may be the first bad poetry Eliot had written, it is made clear that he was conscious of the seeming hollowness of ecclesiastical utterances. It may seem paradoxical that Eliot, in this propaganda setting, was actually trying to wring the neck of rhetoric, and the moral is even enforced by his inclusion of a verse-sketch which clearly shows an adulteration through rhetoric. Chapter IV reverberates on the two preceding chapters in its delineation of a return to a purified yet traditional language as well. Although the nobility of language from biblical books is still there, Eliot was for the first time using a democratic, and non-hieratic, language of ordinary man. There is a new distrust of the cunning and rhetorical, as contained in the 'objective correlative' of before, and the author is attempting a personal atone through what seems to be an authenticity and sincerity of tone. The Rock could conceivably exist without the choruses at all but they are important, unlike the prose episodes, because they were written without the various collaborators. Chapter V attempts, very briefly, to establish that The Rock was not a propagandist's hackwork but that the author was consciously groping for new forms of prosody and dramatic techniques preparatory to his later plays and…
Subjects/Keywords: Eliot; T. S. 1888-1965
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kennedy, D. J. (1973). A study of The Rock by T.S. Eliot. (Masters Thesis). Massey University. Retrieved from http://hdl.handle.net/10179/13874
Chicago Manual of Style (16th Edition):
Kennedy, D J. “A study of The Rock by T.S. Eliot.” 1973. Masters Thesis, Massey University. Accessed December 07, 2019.
http://hdl.handle.net/10179/13874.
MLA Handbook (7th Edition):
Kennedy, D J. “A study of The Rock by T.S. Eliot.” 1973. Web. 07 Dec 2019.
Vancouver:
Kennedy DJ. A study of The Rock by T.S. Eliot. [Internet] [Masters thesis]. Massey University; 1973. [cited 2019 Dec 07].
Available from: http://hdl.handle.net/10179/13874.
Council of Science Editors:
Kennedy DJ. A study of The Rock by T.S. Eliot. [Masters Thesis]. Massey University; 1973. Available from: http://hdl.handle.net/10179/13874

University of Johannesburg
21.
Tshomela, Zibonele.
Social and political concerns as addressed by three prominent Xhosa poets.
Degree: 2011, University of Johannesburg
URL: http://hdl.handle.net/10210/4140
► M.A.
This study is a critical assessment and analysis of Xhosa poetry that addresses social and political concerns with particular reference to the poetry of…
(more)
▼ M.A.
This study is a critical assessment and analysis of Xhosa poetry that addresses social and political concerns with particular reference to the poetry of Qangule (1970), Mtuze (1982, 1990) and Xozwa (1994 ). Chapter one introduces the study by presenting its aim, scope, method of research, theory, definition of concepts and significance of the study. Chapter 2 focuses on the theoretical framework of the study. It discusses the theory of Marxism, which is used as a basis of this study, by explaining the concept of Marxism, its historical background, assumptions, methodology and Marxism and poetry. Chapter 3 deals with social concerns that are addressed by Mtuze (1982 and 1990) and Xozwa (1994 ). These social concerns are divorce and alcohol usage. The discussion in this chapter focuses on how divorce affects members of the family concerned, especially children of divorced parents. It also looks at how alcohol is used in society. While the discussion in this chapter acknowledges moderate use of alcohol, it focuses more on how this substance may also be abused. It looks at how alcohol abuse affects individuals and society economically and how dangerous it is to the health and lives of people. Chapter 4 focuses on political concerns as addressed by Qangule (1970) and Mtuze (1982). It assesses and analyses poems that address the oppression of black people during the apartheid regime in South Africa. Concerns like citizenship and deprivation of freedom, labour conditions and language are discussed in this chapter. Chapter 5 is a concluding statement which gives a summary of the study, evaluation of Xhosa poetry with regard to addressing the concerns discussed in the study and recommendations regarding future research.
Subjects/Keywords: Qangule, Z. S.; Xozwa, L. W. M.; Mtuze, P. T.
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Tshomela, Z. (2011). Social and political concerns as addressed by three prominent Xhosa poets. (Thesis). University of Johannesburg. Retrieved from http://hdl.handle.net/10210/4140
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Tshomela, Zibonele. “Social and political concerns as addressed by three prominent Xhosa poets.” 2011. Thesis, University of Johannesburg. Accessed December 07, 2019.
http://hdl.handle.net/10210/4140.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Tshomela, Zibonele. “Social and political concerns as addressed by three prominent Xhosa poets.” 2011. Web. 07 Dec 2019.
Vancouver:
Tshomela Z. Social and political concerns as addressed by three prominent Xhosa poets. [Internet] [Thesis]. University of Johannesburg; 2011. [cited 2019 Dec 07].
Available from: http://hdl.handle.net/10210/4140.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Tshomela Z. Social and political concerns as addressed by three prominent Xhosa poets. [Thesis]. University of Johannesburg; 2011. Available from: http://hdl.handle.net/10210/4140
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Oregon
22.
Lisiecki, Chet.
Lyric Poetry, Conservative Poetics, and the Rise of Fascism.
Degree: 2014, University of Oregon
URL: http://hdl.handle.net/1794/18532
► As fascist movements took hold across Europe in the 1920s and 1930s, there emerged a body of lyric poetry concerned with revolution, authority, heroism, sacrifice,…
(more)
▼ As fascist movements took hold across Europe in the 1920s and 1930s, there emerged a body of lyric poetry concerned with revolution, authority, heroism, sacrifice, community, heritage, and national identity. While the Nazi rise to power saw the deception, persecution, and brutalization of conservatives both in the Reichstag and in the streets, these themes resonated with fascists and conservatives alike, particularly in Germany. Whether they welcomed the new regime out of fear or opportunism, many conservative beneficiaries of National Socialism shared, and celebrated in poetry, the same ideological principles as the fascists.
Such thematic continuities have made it seem as though certain conservative writers, including
T.
S. Eliot, Stefan George, and Hugo von Hofmannsthal, were proto-fascist, their work cohering around criteria consonant with fascist ideology. My dissertation, however, emphasizes the limits of such cohesion, arguing that fascist poetry rejects, whereas conservative poetry affirms, the possibility of indeterminacy and inadequacy. While the fascist poem blindly believes it can effect material political change, the conservative poem affirms the failure of its thematic content to correspond entirely to material political reality. It displays neither pure political commitment nor aesthetic autonomy, suspending these categories in an unresolved tension.
Paul de Man'
s work on allegory hinges on identifying a reading practice that addresses this space between political commitment and aesthetic autonomy. His tendency to forget the immanence of history, however, is problematic in the context of fascism. Considering rhetorical formalism alongside dialectical materialism, in particular Adorno'
s essay "Lyric Poetry and Society," allows for a more rounded and ethical methodological approach. The poetic dramatization of the very indeterminacy that historically constituted conservative politics in late-Weimar Germany both distinguishes the conservative from the fascist poem while also accounting for its complicity. Fascism necessitated widespread and wild enthusiasm, but it also succeeded through the (unintentional) proliferation of political indifference as registered, for example, by the popularity of entertainment literature. While the work of certain conservative high modernists reflected critically on its own failures, such indeterminacy nonetheless resembles the failure to politically commit oneself against institutionalized violence and systematic oppression.
Advisors/Committee Members: Librett, Jeffrey S. (advisor).
Subjects/Keywords: Fascism; Modernism; Paul de Man; Poetry; Stefan George; T. S. Eliot
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Lisiecki, C. (2014). Lyric Poetry, Conservative Poetics, and the Rise of Fascism. (Thesis). University of Oregon. Retrieved from http://hdl.handle.net/1794/18532
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Lisiecki, Chet. “Lyric Poetry, Conservative Poetics, and the Rise of Fascism.” 2014. Thesis, University of Oregon. Accessed December 07, 2019.
http://hdl.handle.net/1794/18532.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Lisiecki, Chet. “Lyric Poetry, Conservative Poetics, and the Rise of Fascism.” 2014. Web. 07 Dec 2019.
Vancouver:
Lisiecki C. Lyric Poetry, Conservative Poetics, and the Rise of Fascism. [Internet] [Thesis]. University of Oregon; 2014. [cited 2019 Dec 07].
Available from: http://hdl.handle.net/1794/18532.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Lisiecki C. Lyric Poetry, Conservative Poetics, and the Rise of Fascism. [Thesis]. University of Oregon; 2014. Available from: http://hdl.handle.net/1794/18532
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
24.
Parker, Donald G.
Frustration and Quest in the Poems and Plays of T. S. Eliot.
Degree: 1969, North Texas State University
URL: https://digital.library.unt.edu/ark:/67531/metadc163937/
► A careful examination of the creative writing of T. S. Eliot reveals that his poetry can be divided for purposed of consideration into two phases.…
(more)
▼ A careful examination of the creative writing of
T.
S. Eliot reveals that his poetry can be divided for purposed of consideration into two phases. The first phase refers to those poems written up to and including "The Hollow Men". These early poems can best be grouped together and characterized by the term frustration. The poetry of the second phase, written after "The Hollow Man," is dominated by and best considered in regard to a quest for the ideal.
Advisors/Committee Members: Sampley, Arthur M. (Arthur McCullough), 1903-1975, Coomes, Edward John, Jr..
Subjects/Keywords: Eliot, T. S.; frustration
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share






University of British Columbia
25.
Brooks, Heather Alleyne.
The literary criticism of Matthew Arnold and T.S. Eliot
.
Degree: 1959, University of British Columbia
URL: http://hdl.handle.net/2429/41678
► Matthew Arnold's literary criticism has recently been recognized as exhibiting a "controlled oscillation" between various antithetical points of view. This thesis analyzes these points of…
(more)
▼ Matthew Arnold's literary criticism has recently
been recognized as exhibiting a "controlled oscillation" between
various antithetical points of view. This thesis analyzes these
points of view, shows how Arnold sometimes succeeded in reconciling
these opposites, and then goes on to show that Eliot's
literary criticism can be analyzed in the same way.
Eliot and Arnold are shown to be both classic and
romantic critics; that is, broadly speaking, to judge both by
rules and by individual impressions. These antithetical limits
are partially, but not entirely synthesized. Next, analysis of
Arnold's criticism leads to the conclusion that Arnold usually
judged literature by the moral ideas it expressed, but that
the ideas were inextricably involved with their literary form.
Eliot finds judgment by idea distasteful because of his commitment
to Church of England dogma, but also tends, although
with less success, toward the synthesis achieved by Arnold.
Another set of antithetical viewpoints held by
Arnold and Eliot are those of the disinterested critic vs. the
social advocate. Again, a partial resolution is suggested.
Close similarity between the two critics' views on the tradition
is demonstrated, but an opposing progressive element in both
men's thought is also revealed. However, the two categories
are shown to be not mutually exclusive.
Finally, the style and critical method of Arnold and
Eliot is analyzed and is seen to exhibit antithetical tendencies.
Both critics alternate between tones of persuasiveness and
exhibitions of tactlessness. Both methods reveal a combination
of analysis and dogmatism, although Eliot's dogmatism is always
admitted to be personal opinion. Neither Arnold nor Eliot
attack a critical problem from the same viewpoint at all times;
they are pragmatic critics who will try any method that seems
to work best at the moment.
Subjects/Keywords: Arnold Matthew;
Eliot, T. S.
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Brooks, H. A. (1959). The literary criticism of Matthew Arnold and T.S. Eliot
. (Thesis). University of British Columbia. Retrieved from http://hdl.handle.net/2429/41678
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Brooks, Heather Alleyne. “The literary criticism of Matthew Arnold and T.S. Eliot
.” 1959. Thesis, University of British Columbia. Accessed December 07, 2019.
http://hdl.handle.net/2429/41678.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Brooks, Heather Alleyne. “The literary criticism of Matthew Arnold and T.S. Eliot
.” 1959. Web. 07 Dec 2019.
Vancouver:
Brooks HA. The literary criticism of Matthew Arnold and T.S. Eliot
. [Internet] [Thesis]. University of British Columbia; 1959. [cited 2019 Dec 07].
Available from: http://hdl.handle.net/2429/41678.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Brooks HA. The literary criticism of Matthew Arnold and T.S. Eliot
. [Thesis]. University of British Columbia; 1959. Available from: http://hdl.handle.net/2429/41678
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Windsor
26.
Wilson, Peter Anthony.
T. S. Eliot's 'Ash-Wednesday'.
Degree: MA, English Language, Literature, and Creative Writing, 1963, University of Windsor
URL: https://scholar.uwindsor.ca/etd/6338
Subjects/Keywords: ASH; ELIOT; S; T; WEDNESDAY
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Wilson, P. A. (1963). T. S. Eliot's 'Ash-Wednesday'. (Masters Thesis). University of Windsor. Retrieved from https://scholar.uwindsor.ca/etd/6338
Chicago Manual of Style (16th Edition):
Wilson, Peter Anthony. “T. S. Eliot's 'Ash-Wednesday'.” 1963. Masters Thesis, University of Windsor. Accessed December 07, 2019.
https://scholar.uwindsor.ca/etd/6338.
MLA Handbook (7th Edition):
Wilson, Peter Anthony. “T. S. Eliot's 'Ash-Wednesday'.” 1963. Web. 07 Dec 2019.
Vancouver:
Wilson PA. T. S. Eliot's 'Ash-Wednesday'. [Internet] [Masters thesis]. University of Windsor; 1963. [cited 2019 Dec 07].
Available from: https://scholar.uwindsor.ca/etd/6338.
Council of Science Editors:
Wilson PA. T. S. Eliot's 'Ash-Wednesday'. [Masters Thesis]. University of Windsor; 1963. Available from: https://scholar.uwindsor.ca/etd/6338
27.
Garreau, Anne.
Caractérisation des processus d'ubiquitination régulant la protéine Themis durant le développement des lymphocytes T : T cells, ubiquitylation, T cell signaling, thymic selection.
Degree: Docteur es, Immunologie, 2017, Université Toulouse III – Paul Sabatier
URL: http://www.theses.fr/2017TOU30025
► Themis est une protéine de signalisation des récepteurs des lymphocytes T (TCR) essentielle pour la sélection positive des cellules T. La fonction moléculaire de Themis…
(more)
▼ Themis est une protéine de signalisation des récepteurs des lymphocytes T (TCR) essentielle pour la sélection positive des cellules T. La fonction moléculaire de Themis a été controversée mais de récentes études suggèrent qu'il est un régulateur positif des voies de signalisation des TCR. Nous avons montré dans une étude préliminaire que Themis interagit avec des déubiquitinases et qu'il est ubiquitiné dans les thymocytes. L'objectif de ma thèse était de caractériser les mécanismes moléculaires qui régulent l'ubiquitination de Themis et de déterminer si ces processus affectent la fonction de Themis durant le développement des lymphocytes T. Nous avons montré que si l'expression des ARNm codant pour Themis diminue dans les stades précoces de la sélection positive, son expression protéique est parallèlement augmentée, suggérant une stabilisation de Themis par des modifications post-traductionnelles durant cette étape. Nous avons montré que la déubiquitinase USP9X déubiquitine Themis pour stabiliser son expression durant la stimulation des TCR. L'ensemble de nos résultats proposent qu'USP9X soit activé durant la stimulation des TCR grâce à son recrutement dans les complexes proximaux des TCR par l'intermédiaire de l'adaptateur Grb2 et Themis, entrainant la stabilisation de l'expression de Themis. Nous pensons que ce mécanisme est important pour maintenir l'expression de Themis durant la sélection positive afin de favoriser l'induction d'un signal des TCR soutenu, requis pour l'efficacité de ce processus.
The protein Themis is a new actor of the T cell receptor (TCR) signaling essential for the positive selection of T cells. The molecular function of Themis has been controversial but recent findings suggest that it acts as positive regulator of TCR signaling. We demonstrated in an initial research that Themis interacts with deubiquitylases and is covalently associated to ubiquitin chains in thymocytes. The aim of my PhD project was to characterize the molecular process that regulates the ubiquitination of Themis and to investigate how these post-translational modifications affect Themis function during T cell development. We demonstrated that Themis mRNA expression is progressively decreased after positive selection whereas Themis protein expression is enhanced at the early stages of positive selection, suggesting that Themis is stabilized by post-translational modifications during positive selection. We demonstrated that USP9X allows the deubiquitination of Themis and its stabilization following TCR engagement. Ours results suggest that USP9X is activated during TCR engagement following its recruitment to proximal signaling complexes through Grb2 and Themis, leading to the deubiquitination and stabilization of Themis expression. We believe that this mechanism is important to sustain Themis expression during positive selection and to promote durable TCR signals required for the efficiency of this process.
Advisors/Committee Members: Lesourne, Renaud (thesis director), Saoudi, Abdelhadi (thesis director).
Subjects/Keywords: Lymphocytes T; Ubiquitination; Signalisation des TCR; Sélection thymique; T cells; Ubiquitylation; T cell signaling; Thymic selection
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Garreau, A. (2017). Caractérisation des processus d'ubiquitination régulant la protéine Themis durant le développement des lymphocytes T : T cells, ubiquitylation, T cell signaling, thymic selection. (Doctoral Dissertation). Université Toulouse III – Paul Sabatier. Retrieved from http://www.theses.fr/2017TOU30025
Chicago Manual of Style (16th Edition):
Garreau, Anne. “Caractérisation des processus d'ubiquitination régulant la protéine Themis durant le développement des lymphocytes T : T cells, ubiquitylation, T cell signaling, thymic selection.” 2017. Doctoral Dissertation, Université Toulouse III – Paul Sabatier. Accessed December 07, 2019.
http://www.theses.fr/2017TOU30025.
MLA Handbook (7th Edition):
Garreau, Anne. “Caractérisation des processus d'ubiquitination régulant la protéine Themis durant le développement des lymphocytes T : T cells, ubiquitylation, T cell signaling, thymic selection.” 2017. Web. 07 Dec 2019.
Vancouver:
Garreau A. Caractérisation des processus d'ubiquitination régulant la protéine Themis durant le développement des lymphocytes T : T cells, ubiquitylation, T cell signaling, thymic selection. [Internet] [Doctoral dissertation]. Université Toulouse III – Paul Sabatier; 2017. [cited 2019 Dec 07].
Available from: http://www.theses.fr/2017TOU30025.
Council of Science Editors:
Garreau A. Caractérisation des processus d'ubiquitination régulant la protéine Themis durant le développement des lymphocytes T : T cells, ubiquitylation, T cell signaling, thymic selection. [Doctoral Dissertation]. Université Toulouse III – Paul Sabatier; 2017. Available from: http://www.theses.fr/2017TOU30025

Université Laval
28.
Trépanier, Patrick.
Effets des immunoglobulines intraveineuses sur la
présentation antigénique et développement de substituts
potentiels.
Degree: 2014, Université Laval
URL: http://hdl.handle.net/20.500.11794/24800
► Les immunoglobulines intraveineuses (IgIV) sont utilisées dans le traitement de maladies auto-immunes et inflammatoires depuis le début des années 1980. L’accroissement constant de la consommation…
(more)
▼ Les immunoglobulines intraveineuses (IgIV) sont
utilisées dans le traitement de maladies auto-immunes et
inflammatoires depuis le début des années 1980. L’accroissement
constant de la consommation des IgIV augmente les risques de
pénuries de ce produit pour lequel il n’existe encore aucun
substitut. La compréhension des mécanismes d’action complexes et
controversés de cet agent thérapeutique permettrait de rationaliser
son utilisation et de développer des substituts. Sachant que les
IgIV sont capables d’interférer avec la présentation d’antigène et
la réponse des lymphocytes T CD4, les travaux présentés se sont
intéressés aux caractéristiques physicochimiques responsables de
ces effets, de même qu’à l’élargissement de nos connaissances des
effets des IgIV sur la présentation et la réponse des lymphocytes T
CD8. Ces connaissances permettront d’établir des fondements
scientifiques pour le développement de substituts. Nous avons
montré dans un premier temps qu’une préparation d’IgIV rendue
fortement cationique (cIgIV) était capable d’inhiber la
présentation d’antigènes et la réponse subséquente des lymphocytes
T CD4 in vitro. Ensuite, des essais ont permis de démontrer la
possibilité d’utiliser les cIgIV avec une bio distribution
améliorée dans le foie et la rate chez la souris, mais le potentiel
thérapeutique amélioré dans un modèle de thrombocytopénie passive
n’a pu être démontré. Le deuxième volet de cette thèse a permis de
dévoiler la capacité des IgIV d’inhiber l’activation et l’expansion
des lymphocytes T CD8 in vitro et chez la souris. De plus, nous
avons fait la preuve de la capacité des IgIV d’inhiber la
cytotoxicité en réduisant l’expression de la perforine et en
bloquant certains récepteurs des cellules T. Ces résultats
permettent d’améliorer notre compréhension du rôle des IgIV dans le
traitement des maladies auto immunes grâce à leur interférence avec
la génération et la cytotoxicité effectrice des lymphocytes T
CD8.
Intravenous immunoglobulins (IVIg) are used in the
treatment of many inflammatory and autoimmune diseases since the
beginning of the 80s. The constant increase of their use exposes
the users and the providers to important shortage risks. A better
understanding of their complex mechanisms of action would help in
developing potential substitutes. Knowing that IVIg are able to
modulate the immune function of antigen presenting cells and the
resulting CD4 T cell response, work presented here questioned the
physicochemical characteristics of IVIg which could be related to
these effects, as well as to the extension of their effect to the
CD8 T cell compartment. In the first part of this thesis, we showed
that cationized IVIg (cIVIg) was capable to inhibit in vitro
antigen presentation. Next, we showed that cIVIg displayed an
ameliorated bio distribution in mice, although the therapeutic
potential of the preparation could not be demonstrated in a passive
model of throbomcytopenia. The second part of this thesis revealed
a novel capacity of IVIg in inhibiting the activation and expansion
of CD8 T…
Advisors/Committee Members: Bazin, Renée, Darveau, André.
Subjects/Keywords: Immunoglobulines – Emploi en
thérapeutique; Lymphocytes T auxiliaires; Lymphocytes T suppresseurs; Antigènes de différenciation des lymphocytes
T
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Trépanier, P. (2014). Effets des immunoglobulines intraveineuses sur la
présentation antigénique et développement de substituts
potentiels. (Thesis). Université Laval. Retrieved from http://hdl.handle.net/20.500.11794/24800
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Trépanier, Patrick. “Effets des immunoglobulines intraveineuses sur la
présentation antigénique et développement de substituts
potentiels.” 2014. Thesis, Université Laval. Accessed December 07, 2019.
http://hdl.handle.net/20.500.11794/24800.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Trépanier, Patrick. “Effets des immunoglobulines intraveineuses sur la
présentation antigénique et développement de substituts
potentiels.” 2014. Web. 07 Dec 2019.
Vancouver:
Trépanier P. Effets des immunoglobulines intraveineuses sur la
présentation antigénique et développement de substituts
potentiels. [Internet] [Thesis]. Université Laval; 2014. [cited 2019 Dec 07].
Available from: http://hdl.handle.net/20.500.11794/24800.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Trépanier P. Effets des immunoglobulines intraveineuses sur la
présentation antigénique et développement de substituts
potentiels. [Thesis]. Université Laval; 2014. Available from: http://hdl.handle.net/20.500.11794/24800
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
29.
Korhonen, Elina.
FDA-määräysten vaikutus tehdasautomaatioon liittyviin tiedonkeruu- ja tuotannonohjausjärjestelmiin
.
Degree: 2019, Theseus
URL: http://www.theseus.fi/handle/10024/170433
► Opinnäytetyön toimeksiantaja oli Asitek Oy, joka on sähkö- ja automaatioalan suunnittelutoimisto. Työn tarkoituksena oli selvittää, minkälaisia vaikutuksia Yhdysvaltain viranomaistahon FDA:n sääntelyllä on lääketeollisuudelle tehtävien MES-…
(more)
▼ Opinnäytetyön toimeksiantaja oli Asitek Oy, joka on sähkö- ja automaatioalan suunnittelutoimisto. Työn tarkoituksena oli selvittää, minkälaisia vaikutuksia Yhdysvaltain viranomaistahon FDA:n sääntelyllä on lääketeollisuudelle tehtävien MES- ja tiedonkeruujärjestelmien suunnitteluun ja toteuttamiseen. Tavoitteena oli tarjota suunnittelijoille taustatietoa lääketeollisuuden projekteissa sovellettavista työtavoista ja rakennettaville järjestelmille asetettavista reunaehdoista.
Yhtenä aiheena käsiteltiin niitä työtapoja, joita FDA edellyttää käytettävän lääketeollisuudelle tehtävissä projekteissa. Tähän tarkoitukseen on olemassa kansainvälisen ISPE-organisaation laatima GAMP 5 -ohjeistus, jossa on kuvattu yksityiskohtaisesti työtavat, joita projektin eri vaiheissa pitää noudattaa. Tämä ohjeistus velvoittaa sekä loppuasiakasta että järjestelmätoimittajaa.
FDA:n julkaisu 21 CFR osa 11 sisältää velvoittavaa ohjeistusta koskien lääketeollisuuden järjestelmien sähköisiä tallenteita ja sähköisiä allekirjoituksia. Kyseistä julkaisua on käsitelty opinnäytetyössä.
Työssä selvitettiin FDA:n sääntelyn vaikutuksia järjestelmien teknisiin ratkaisuihin ja niiden toteuttamismahdollisuuksiin eri näkökulmista. Tuloksena syntyi selvitys lääketeollisuuden kohteisiin soveltuvista kaupallisista ohjelmistoalustoista, joiden avulla voidaan toteuttaa FDA:n vaatimukset täyttäviä järjestelmiä. Lisäksi työssä pohdittiin mahdollisuuksia toteuttaa FDA-säännelty järjestelmä alusta alkaen omalla kooditoteutuksella ja siihen liittyviä haasteita. Tämä pohdinta kuuluu yrityssalaisuuden piiriin eli ei näin ollen ole opinnäytetyön julkaistavassa versiossa.; The thesis was commissioned by Asitek Oy, an electrical and automation engineering agency. The purpose of this thesis was to investigate the impact of the US authority FDA’s regulation on the design and implementation of MES and data collection systems for the pharmaceutical industry. The aim was to provide designers with background information on the working methods applied in pharmaceutical projects and on the boundary conditions to be set for the systems to be built.
Concerning the working methods in pharmaceutical projects, there is a GAMP 5 guidance prepared by an international ISPE organization. This guidance describes in detail, the working methods to be followed at different stages of the project. FDA recommends both the end customer and the system vendor to apply GAMP 5 guidance.
FDA has issued the binding guidelines regarding electronic recordings and electronic signatures of pharmaceutical systems. This regulation is considered in publication 21 CFR Part 11, which is an important source of information in this thesis.
The work clarified the impact of FDA regulation on the technical solutions of systems and their implementation possibilities from different perspectives. The result was a study of commercial software platforms suitable for pharmaceutical industries. By using those platforms it is possible to implement FDA-compliant systems. The thesis also produced a…
Subjects/Keywords: MES-järjestelmä;
FDA-sääntely
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Korhonen, E. (2019). FDA-määräysten vaikutus tehdasautomaatioon liittyviin tiedonkeruu- ja tuotannonohjausjärjestelmiin
. (Thesis). Theseus. Retrieved from http://www.theseus.fi/handle/10024/170433
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Korhonen, Elina. “FDA-määräysten vaikutus tehdasautomaatioon liittyviin tiedonkeruu- ja tuotannonohjausjärjestelmiin
.” 2019. Thesis, Theseus. Accessed December 07, 2019.
http://www.theseus.fi/handle/10024/170433.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Korhonen, Elina. “FDA-määräysten vaikutus tehdasautomaatioon liittyviin tiedonkeruu- ja tuotannonohjausjärjestelmiin
.” 2019. Web. 07 Dec 2019.
Vancouver:
Korhonen E. FDA-määräysten vaikutus tehdasautomaatioon liittyviin tiedonkeruu- ja tuotannonohjausjärjestelmiin
. [Internet] [Thesis]. Theseus; 2019. [cited 2019 Dec 07].
Available from: http://www.theseus.fi/handle/10024/170433.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Korhonen E. FDA-määräysten vaikutus tehdasautomaatioon liittyviin tiedonkeruu- ja tuotannonohjausjärjestelmiin
. [Thesis]. Theseus; 2019. Available from: http://www.theseus.fi/handle/10024/170433
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
30.
Reimann, Christian.
In-vitro Generation of potent T-lymphoid Progenitors in a feeder-cell-free DL-4 system : Génération des progéniteurs lymphoïdes T ex vivo par exposition brève au ligand de Notch DL-4.
Degree: Docteur es, Immunologie, 2012, Université Paris Descartes – Paris V
URL: http://www.theses.fr/2012PA05T033
► L’allogreffe des cellules souches hématopoïétiques (CSH) dans les situations d’incompatibilité HLA partielle représente une option thérapeutique irremplaçable pour des patients nécessitant une greffe de cellules…
(more)
▼ L’allogreffe
des cellules souches hématopoïétiques (CSH) dans les situations d’incompatibilité HLA partielle représente une option thérapeutique irremplaçable pour
des patients nécessitant une greffe de cellules souches hématopoïétiques, en absence d’un donneur HLA-identique. Toutefois, le retard de la restauration du système immunitaire en particulier dans du compartiment lymphocytaire aprè
s greffe est l'une
des complications majeures. Une nouvelle stratégie pour promouvoir la reprise de la thymopoïèse à partir
des CSH provenant du donneur et d'accélérer la reconstitution cellulaire
T chez
des patients aprè
s greffe de CSH consiste en le transfert adoptif
des progéniteurs
T généré
s in vitro. L’identification de Notch1 comme le régulateur-clé du développement lymphocytaire
T a permis l’établissement de systè
mes de culture à base de ligands de Notch, qui permettent la génération efficace de progéniteurs lymphoï
des T in vitro. L'efficacité
des progeniteurs
T-lymphoï
des murins pour promouvoir la reconstitution
des lymphocytes
T a été bien démontrée dans
des modèles de greffe chez la souris. De même,
des progéniteurs
T-lymphopoïétiques humains généré
s in vitro et greffé
s aux souris humanisées favorisent la reprise de la thymopoïèse. Pourtant, aucune donnée n’a encore démontré leur capacité à donner naissance à un compartiment lymphocytaire
T périphérique. De plus, les systè
mes de co-culture à base de ligand de Notch actuellement utilisé
s consistent en
des lignées stromales murines génétiquement modifiées. Afin d'établir un système cliniquement applicable, il est donc indispensable d’établir
des systè
mes de culture qui soutiennent la génération de progéniteurs
T en absence d’un support
des cellules nourricières. Au cours de mon projet de thèse, j'ai développé un nouveau système de culture pour la génération
des progéniteurs
T-lymphopoïétiques humains
T basé sur l’immobilisation du ligand de Notch Delta-like-4 (DL-4) sous sa forme protéique. La culture
des progéniteurs hématopoïétiques CD34+ issue de sang en présence de DL-4 immobilisé permet la génération d’un grand nombre de cellules ayant un phénotype de progéniteurs thymiques précoces (early thymic progenitor: ETP) et de prothymocytes (proT). Les cellules ETP et ProT ainsi générées expriment à
des niveaux élevé
s des gènes impliqué
s dans le développement lymphocytaire précoce (i.e. pTa, Rag1, IL7Ra et BCL11b). Elles montrent
des signes de réarrangement du récepteur
des cellules
T (TCR) similaires à leurs homologues thymiques. Par
des expériences de dilution limite sur une co-culture OP9/DL-1 secondaire, j’ai pu montrer que les progéniteurs généré
s sur DL-4 possédaient un potentiel lymphoïde
T trè
s augmenté, qui pourrait être entièrement attribué aux sous populations ETP et ProT. Suite à leur transfert dans
des souris NOD/SCID/γc-/-, les progéniteurs lymphoïde
T généré
s par exposition a DL-4 sont capable de migrer dans le thymus, d’y poursuivre
des étapes ultérieures de leur développement et d’accélérer la différentiation
T intra thymique ainsi que l’émergence
des…
Advisors/Committee Members: André-Schmutz, Isabelle (thesis director).
Subjects/Keywords: Développement des lymphocytes T; Progéniteurs lymphoïdes T; Notch1; Ligand de Notch DL-4; Reconstitution immunitaire après greffe des CSH; T cell development; T-lymphoid progenitor cells; Notch1; DL-4 protein; Immunereconstitution after HSCT; T-Zellentwicklung; T-Vorläuferzellen; Notch1; Notchligand DL-4; Immunrekonstitution nach HSZT
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share





❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Reimann, C. (2012). In-vitro Generation of potent T-lymphoid Progenitors in a feeder-cell-free DL-4 system : Génération des progéniteurs lymphoïdes T ex vivo par exposition brève au ligand de Notch DL-4. (Doctoral Dissertation). Université Paris Descartes – Paris V. Retrieved from http://www.theses.fr/2012PA05T033
Chicago Manual of Style (16th Edition):
Reimann, Christian. “In-vitro Generation of potent T-lymphoid Progenitors in a feeder-cell-free DL-4 system : Génération des progéniteurs lymphoïdes T ex vivo par exposition brève au ligand de Notch DL-4.” 2012. Doctoral Dissertation, Université Paris Descartes – Paris V. Accessed December 07, 2019.
http://www.theses.fr/2012PA05T033.
MLA Handbook (7th Edition):
Reimann, Christian. “In-vitro Generation of potent T-lymphoid Progenitors in a feeder-cell-free DL-4 system : Génération des progéniteurs lymphoïdes T ex vivo par exposition brève au ligand de Notch DL-4.” 2012. Web. 07 Dec 2019.
Vancouver:
Reimann C. In-vitro Generation of potent T-lymphoid Progenitors in a feeder-cell-free DL-4 system : Génération des progéniteurs lymphoïdes T ex vivo par exposition brève au ligand de Notch DL-4. [Internet] [Doctoral dissertation]. Université Paris Descartes – Paris V; 2012. [cited 2019 Dec 07].
Available from: http://www.theses.fr/2012PA05T033.
Council of Science Editors:
Reimann C. In-vitro Generation of potent T-lymphoid Progenitors in a feeder-cell-free DL-4 system : Génération des progéniteurs lymphoïdes T ex vivo par exposition brève au ligand de Notch DL-4. [Doctoral Dissertation]. Université Paris Descartes – Paris V; 2012. Available from: http://www.theses.fr/2012PA05T033
◁ [1] [2] [3] [4] [5] … [1339] ▶
.