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University of Cincinnati

1. Chiu, Shih-Feng. The Effect of Changing Batch Frequency, Lead Time and Installing an I.V. Workflow Management System on Intravenous Admixture Operations in a Pediatric Hospital.

Degree: PhD, Pharmacy: Pharmaceutical Sciences/Biopharmaceutics, 2014, University of Cincinnati

PURPOSE: The purpose of this dissertation was to study the effect of changing the i.v. batch schedule (changing i.v. batch frequency and changing preparation lead time) and installing the new i.v. workflow management system: DoseEdge® system with the current CCHMC i.v. operations. The hospital database analysis, mathematical model and computer simulation model were applied as study research tools. The final goal was to determine the two i.v. batch schedules that would offer the maximum savings of monthly wasted cost. One of the i.v. batch schedules for the pharmacy i.v. operation was without the DoseEdge® system, and the other i.v. batch schedule for the pharmacy i.v. operation was with the DoseEdge® system. OBJECTIVES: The objectives were: (1) to estimate the number of wasted i.v. doses, cost of wasted i.v. doses and the number of extra i.v. dose errors in the existing CCHMC i.v. operations, (2) to estimate the effect of changing i.v. batch frequency and lead time on the number of wasted i.v. doses, cost of wasted i.v. doses and the number of extra i.v. dose errors, (3) to estimate the effect of installing the DoseEdge® System with various combinations of batch frequency and lead time on completion rate of i.v. batch schedule, utilization rate of hoods, utilization rate of pharmacists and utilization rate of technicians, and (4) to determine the optimal i.v. batch schedule (combination of i.v. batch frequency and lead time) with or without the DoseEdge® System for the CCHMC i.v. operations. RESULTS: The study site is Cincinnati Children’s Hospital Medical Center (CCHMC), which is a 512-bed pediatric hospital located in Cincinnati, Ohio. The CCHMC i.v. room is located in the main pharmacy at the Division of Pharmacy. The DoseEdge® i.v. workflow management system was installed in 2011. The database analysis results of the current CCHMC i.v. operation from October 2011 to March 2012 showed that the monthly number of i.v. wasted doses was 8,599, the monthly cost of i.v. wasted doses was $109,271, and the monthly extra dose error rate was 0.13%. For the CCHMC i.v. operation, the i.v. batch schedule without the DoseEdge® system was determined to be three batches per day with two hours lead time. The cost of wasted i.v. doses was reduced by 84.4% to $17,033 per month, and the potential number of extra i.v. dose errors was reduced by 84.8% to 1.7 doses per month. For the CCHMC i.v. operation, the i.v. batch schedule with the DoseEdge® system was determined to be three batches per day with three hours lead time. The cost of wasted i.v. doses was decreased by 81.8% to $19,910 per month, and the potential number of extra i.v. dose errors was reduced 82.1% to 2.0 doses per month. CONCLUSIONS: The study proved that changing the batch frequencies and lead time can reduce the i.v. wastes and potential extra i.v. dose errors significantly and installing the DoseEdge® system can change the utilization rates of hoods and staff, without changing the staff numbers in the i.v. operation. Advisors/Committee Members: Lin, Alex (Committee Chair).

Subjects/Keywords: Pharmaceuticals; i v batch frequency; Preparation lead time; system; Wasted cost; Extra dose error; Optimal Batch Schedule

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Chiu, S. (2014). The Effect of Changing Batch Frequency, Lead Time and Installing an I.V. Workflow Management System on Intravenous Admixture Operations in a Pediatric Hospital. (Doctoral Dissertation). University of Cincinnati. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=ucin1397736409

Chicago Manual of Style (16th Edition):

Chiu, Shih-Feng. “The Effect of Changing Batch Frequency, Lead Time and Installing an I.V. Workflow Management System on Intravenous Admixture Operations in a Pediatric Hospital.” 2014. Doctoral Dissertation, University of Cincinnati. Accessed September 17, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1397736409.

MLA Handbook (7th Edition):

Chiu, Shih-Feng. “The Effect of Changing Batch Frequency, Lead Time and Installing an I.V. Workflow Management System on Intravenous Admixture Operations in a Pediatric Hospital.” 2014. Web. 17 Sep 2019.

Vancouver:

Chiu S. The Effect of Changing Batch Frequency, Lead Time and Installing an I.V. Workflow Management System on Intravenous Admixture Operations in a Pediatric Hospital. [Internet] [Doctoral dissertation]. University of Cincinnati; 2014. [cited 2019 Sep 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=ucin1397736409.

Council of Science Editors:

Chiu S. The Effect of Changing Batch Frequency, Lead Time and Installing an I.V. Workflow Management System on Intravenous Admixture Operations in a Pediatric Hospital. [Doctoral Dissertation]. University of Cincinnati; 2014. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=ucin1397736409

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