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You searched for subject:(Post surgical analgesia). Showing records 1 – 3 of 3 total matches.

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Dalhousie University

1. Liu, Jean. Further Studies in Adenosinergic and Monoaminergic Mechanisms of Analgesia by Amitriptyline.

Degree: MS, Department of Pharmacology with Neuroscience, 2012, Dalhousie University

In this thesis, rodent models of chronic pain were used to explore analgesic mechanisms that may potentially be engaged in spinal and peripheral compartments by systemically-administered amitriptyline, a tricyclic antidepressant. The first project (Chapter 2) identified the roles of spinal adenosine A1 and serotonin 5-HT7 receptors, as well as of peripheral adenosine A1 receptors, in the acute antinociceptive effects of amitriptyline in mice. The second project (Chapter 3) examined the potential utility of amitriptyline as a preventive analgesic against persistent post-surgical pain, and involved perioperative administration of amitriptyline after peripheral nerve injury in rats. Changes in post-injury behavioural outcomes, as well as spinal noradrenergic sprouting, were assessed. Overall, spinal serotonergic pathways linked to adenosine A1 receptors, as well as peripheral adenosine A1 receptors, appear to be important in antinociception by amitriptyline. Preventive analgesia by this drug does not appear to result from anatomical changes in spinal noradrenergic pathways. Advisors/Committee Members: Kazue Semba (external-examiner), Eileen Denovan-Wright (graduate-coordinator), Jason McDougall (thesis-reader), Jana Sawynok (thesis-supervisor), Received (ethics-approval), Not Applicable (manuscripts), Not Applicable (copyright-release).

Subjects/Keywords: amitriptyline; persistent post-surgical pain; adenosine A1 receptor; serotonin 5-HT7 receptor; formalin test; antinociception; spared nerve injury; preventive analgesia; antidepressants; pain

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Liu, J. (2012). Further Studies in Adenosinergic and Monoaminergic Mechanisms of Analgesia by Amitriptyline. (Masters Thesis). Dalhousie University. Retrieved from http://hdl.handle.net/10222/15329

Chicago Manual of Style (16th Edition):

Liu, Jean. “Further Studies in Adenosinergic and Monoaminergic Mechanisms of Analgesia by Amitriptyline.” 2012. Masters Thesis, Dalhousie University. Accessed March 07, 2021. http://hdl.handle.net/10222/15329.

MLA Handbook (7th Edition):

Liu, Jean. “Further Studies in Adenosinergic and Monoaminergic Mechanisms of Analgesia by Amitriptyline.” 2012. Web. 07 Mar 2021.

Vancouver:

Liu J. Further Studies in Adenosinergic and Monoaminergic Mechanisms of Analgesia by Amitriptyline. [Internet] [Masters thesis]. Dalhousie University; 2012. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/10222/15329.

Council of Science Editors:

Liu J. Further Studies in Adenosinergic and Monoaminergic Mechanisms of Analgesia by Amitriptyline. [Masters Thesis]. Dalhousie University; 2012. Available from: http://hdl.handle.net/10222/15329


Technical University of Lisbon

2. Godinho, Ricardo Freire. Analgesia pós-cirúrgica em correcções de deslocamento de abomaso à esquerda.

Degree: 2011, Technical University of Lisbon

Dissertação de Mestrado Integrado em Medicina Veterinária

A identificação da dor animal é um aspecto com cada vez maior importância na produção animal, assim como o é minimizar os processos dolorosos ao longo de todos os procedimentos de produção. Quando não for possível eliminar esses estímulos dolorosos, deve ser dada prioridade à devida analgesia. Um desses procedimentos dolorosos é a cirurgia, neste caso, a cirurgia correctiva de deslocamento de abomaso à esquerda. Como não é possível eliminar os estímulos dolorosos resultantes da cirurgia, o que nos resta é proceder à devida analgesia pós-cirúrgica. O objectivo deste trabalho foi perceber se a administração de carprofeno possui maior duração de analgesia do que a flunixina meglumina no maneio de dor pós-cirúrgico na correcção de Deslocamento de Abomaso à Esquerda (DAE). O carprofeno, tal como a flunixina meglumina, é um anti-inflamatório não esteróide, mas é menos utilizado na analgesia pós-cirúrgica devido ao seu custo, apesar de possuir um tempo de semi-vida superior ao da flunixina meglumina. O estudo foi realizado em 26 vacas de raça Holstein Frísia submetidas a correcção cirúrgica de DAE, que foram divididas em dois grupos: Grupo F (14 animais submetidos à administração de flunixina meglumina) e o Grupo C (12 animais submetidos à administração de carprofeno). A analgesia pós-cirúrgica foi avaliada utilizando parâmetros produtivos (produção leiteira nos 8 dias após a cirurgia) e utilizando parâmetros fisiológicos (corpos cetónicos por mensuração de β-hidroxibutiratos sanguíneos no dia 1, 2 e 4). Concluiu-se que não existem diferenças os entre fármacos na analgesia pós-cirúrgica na correcção de DAE, e que para obter resultados mais fidedignos mais estudo serão necessários no futuro.

ABSTRACT - Post-surgical analgesia adjustments left-side displacement of the abomasum - The identification of animal pain is an aspect with growing importance in animal production, as well as minimize the painful processes across all production procedures. When it´s not possible the elimination of the painful stimuli, the analgesia must be prioritized. One of this painful procedures is surgery, in this case, the corrective surgery of the left displaced abomasums (LDA). It is appropriate to perform postoperative analgesia since the elimination of painful stimuli resulting from surgery cannot be done. The objective of this work was to understand if the administration of carprofen has a longer duration of analgesia than the administration of flunixin meglumine in the management of postoperative pain in surgical correction of LDA. Carprofen, as flunixin meglumine, is an anti-inflammatory non esteriod, but it’s less is used, for postoperative analgesia, because of its cost, despite having a half-life greater than flunixin meglumine. The study was conducted on 26 Holstein Friesian cows undergoing surgical correction of LDA, which were divided into two groups: Group F (submitted to the administration of flunixin meglumine) and Group C (submitted to the administration of…

Advisors/Committee Members: Gomes, Elsa Bastos Carriço Monteiro Grillo, Stilwell, George Thomas.

Subjects/Keywords: Analgesia pós-cirúrgica; Dor; Deslocamento de abomaso à esquerda; Carprofeno; Flunixina Meglumina; Post-surgical analgesia; Pain; Left-side displacement of the abomasum; Carprofen; Flunixin meglumine

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Godinho, R. F. (2011). Analgesia pós-cirúrgica em correcções de deslocamento de abomaso à esquerda. (Thesis). Technical University of Lisbon. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/3579

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Godinho, Ricardo Freire. “Analgesia pós-cirúrgica em correcções de deslocamento de abomaso à esquerda.” 2011. Thesis, Technical University of Lisbon. Accessed March 07, 2021. http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/3579.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Godinho, Ricardo Freire. “Analgesia pós-cirúrgica em correcções de deslocamento de abomaso à esquerda.” 2011. Web. 07 Mar 2021.

Vancouver:

Godinho RF. Analgesia pós-cirúrgica em correcções de deslocamento de abomaso à esquerda. [Internet] [Thesis]. Technical University of Lisbon; 2011. [cited 2021 Mar 07]. Available from: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/3579.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Godinho RF. Analgesia pós-cirúrgica em correcções de deslocamento de abomaso à esquerda. [Thesis]. Technical University of Lisbon; 2011. Available from: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/3579

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

3. Bjerså, Kristofer. Complementary and Alternative Therapies in Surgical Care.

Degree: 2012, University of Gothenburg / Göteborgs Universitet

International and national use of complementary and alternative medicine (CAM) is high in the general population and among patients. The level of knowledge about CAM among health care professions is low, but an interest in receiving education about this field has been observed. Concerning surgical care, previous studies indicate a wide range of CAM use among patients, but the level of knowledge among health care professions is poorly investigated, both internationally and in Sweden. Concerning CAM therapies in the management of signs and symptoms in surgical care, transcutaneous electric nerve stimulation (TENS) was used with a variety of effectiveness and osteopathic medicine was found to be poorly investigated in this context. The overall objective of this thesis was to investigate CAM in the surgical context with a focus on health care professions’ perceptions and understanding and the usefulness of therapy in symptom management in clinical settings. Both inductive (paper I; semi structured interviews, n=16) and deductive (paper II; questionnaire, n=737) methods were used to investigate perceptions and understanding of CAM among Swedish health care professions in surgical care. TENS as a pain relieving complement during the transition from epidural analgesia (EDA) to general analgesia after major abdominal surgery was investigated in a randomized controlled trial design (paper III; n=20). Osteopathic intervention in management of chronic signs and symptoms after thoracotomy was investigated with a single-subject research design (paper IV; n=8). The results reveal that surgical health care professions understand and perceive CAM as a wide range of therapies, remedies and systems. Their self valued level of knowledge was low, both concerning CAM and CAM research, but a desire was found to gain knowledge about CAM. A majority of the participants would consider learning a CAM therapy. Dialog about and referral to CAM occurred, but to a limited extent. Concerning therapy usability, TENS was not found to significantly relieve pain, promote recovery or reduce consumption of analgesics. In addition, comments from nurses and patients indicated that TENS treatment obstructed postoperative care. A significant improvement was observed in the osteopathic intervention in stiffness and benefits for pain, but not in breathing. The comprehensive conclusion of the thesis is that Swedish health care professions recognise the concept of CAM and some of its therapies, but their knowledge is in general low. Concerning therapy usability and the effectiveness of CAM in surgical care, the context is essential; TENS after major abdominal surgery in EDA elimination is questionable as concerns pain and its clinical application, while osteopathy may be beneficial in the management of chronic signs and symptoms after thoracotomy.

Subjects/Keywords: Complementary Therapies; Komplementära terapier; Complementary medicine; Komplementära metoder; Complementary and Alternative medicine (CAM); Komplementär och alternativmedicin (KAM); Surgery; Kirurgi; Surgical Care; Kirurgisk vård; Transcutaneous electric nerve stimulation (TENS); Osteopathic Medicine; Osteopati; Perceptions; Uppfattningar; Knowledge; Kunskap; Epidural Analgesia; Post-thoracic symptoms

…among Swedish registered professions in surgical care. Complementary Therapies in Clinical… …providers in Swedish surgical care: a national survey among university hospitals. BMC… …from epidural to general analgesia after pancreatic resection. Submitted. IV. Bjerså, K… …1.1.3 Surgical care… …surgical care ................................ 17 1.2 Transcutaneous electrical nerve stimulation… 

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Bjerså, K. (2012). Complementary and Alternative Therapies in Surgical Care. (Thesis). University of Gothenburg / Göteborgs Universitet. Retrieved from http://hdl.handle.net/2077/29720

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Bjerså, Kristofer. “Complementary and Alternative Therapies in Surgical Care.” 2012. Thesis, University of Gothenburg / Göteborgs Universitet. Accessed March 07, 2021. http://hdl.handle.net/2077/29720.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Bjerså, Kristofer. “Complementary and Alternative Therapies in Surgical Care.” 2012. Web. 07 Mar 2021.

Vancouver:

Bjerså K. Complementary and Alternative Therapies in Surgical Care. [Internet] [Thesis]. University of Gothenburg / Göteborgs Universitet; 2012. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/2077/29720.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bjerså K. Complementary and Alternative Therapies in Surgical Care. [Thesis]. University of Gothenburg / Göteborgs Universitet; 2012. Available from: http://hdl.handle.net/2077/29720

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

.