You searched for subject:(Polydopamine).
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University of Waterloo
1.
Yang, Fut.
Self-polymerized Dopamine Thin Film as Bioadhesive.
Degree: 2012, University of Waterloo
URL: http://hdl.handle.net/10012/6531 
► Dopamine is an interesting biomolecule that functions as a neurotransmitter in the brain. It has been found able to stick to almost all surfaces due…
(more)
▼ Dopamine is an interesting biomolecule that functions as a neurotransmitter in the brain. It has been found able to stick to almost all surfaces due to its unique catecholamine structure. Under alkaline conditions, the catechol functional group oxidizes to quinone allowing dopamine to self-polymerize and form thin films on support surfaces. The facts that dopamine can be coated to virtually any materials and the amine and catechol functional groups support a variety of reactions with organic species make polydopamine an attractive multifunctional bioadhesive/coating. To date, most of research on polydopamine has been focusing on its applications as thin films and little attention has been paid to the adhesion aspect of the material.
In the study, we evaluated the properties of self-polymerized dopamine thin films as a bioadhesive. The thesis consists of three consecutive studies: (i) characterization of the adhesion properties of polydopamine thin films; (ii) investigation of the mechanical properties of polydopamine thin films; and (iii) exploration of the potential of polydopamine thin films as a wet adhesive. Fundamental insights on the wettability, adhesion behaviours, and mechanical properties of polydopamine thin films for both wet and dry conditions were derived through sets of well-designed contact angle, contact adhesion, and contact deformation experiments. It was found that dopamine is able to coat plastic, ceramic and metal surfaces, and join or bond rigid substrates but might not be suitable for joining soft or flexible parts as polydopamine is fairly rigid and the bonding might be too slow and too rigid for practical applications if polydopamine is directly used as an adhesive. Based on the understanding, a new strategy for fabricating underwater adhesive was proposed and tested. In the strategy, polydopamine with ferric ion as the oxidant was utilized as a cross-linker to alginate solution, effectively turning the solution into a wet adhesive, which demonstrated better practical performances than other studies; the adhesive was able to produce a permanent tensile adhesive strength of 80 kPa joining aluminum and glass with macroscopic roughness at the interface within 2 hours of curing time.
Inspired by the results from the contact deformation experiments, we were able to extend the JKR theory with the well-known plate theory to accommodate the deformation of nanometer thin films, obtaining their elasticity. We termed this extended theory the “thin film contact mechanics” and validated the theory against gold thin films and found it predicted the mechanical behaviours of the thin films fairly well.
Subjects/Keywords: wet adhesive; polydopamine
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APA (6th Edition):
Yang, F. (2012). Self-polymerized Dopamine Thin Film as Bioadhesive. (Thesis). University of Waterloo. Retrieved from http://hdl.handle.net/10012/6531
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Yang, Fut. “Self-polymerized Dopamine Thin Film as Bioadhesive.” 2012. Thesis, University of Waterloo. Accessed February 28, 2021.
http://hdl.handle.net/10012/6531.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Yang, Fut. “Self-polymerized Dopamine Thin Film as Bioadhesive.” 2012. Web. 28 Feb 2021.
Vancouver:
Yang F. Self-polymerized Dopamine Thin Film as Bioadhesive. [Internet] [Thesis]. University of Waterloo; 2012. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/10012/6531.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Yang F. Self-polymerized Dopamine Thin Film as Bioadhesive. [Thesis]. University of Waterloo; 2012. Available from: http://hdl.handle.net/10012/6531
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
NSYSU
2.
Peng, Shi-wei.
Investigation of Bio-Inspired Polydopamine Using Atomic Force Microscopy.
Degree: Master, Chemistry, 2015, NSYSU
URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0621115-154800
► Dopamine solution will conduct autoxidation and self-polymerization to form polydopamine particles in alkaline tris-(hydroxymethyl)aminomethane (Tris) buffer solution. At the same time, the ploydopamine deposition onto…
(more)
▼ Dopamine solution will conduct autoxidation and self-polymerization to form
polydopamine particles in alkaline tris-(hydroxymethyl)aminomethane (Tris) buffer solution. At the same time, the ploydopamine deposition onto various substrates via
covalent bond or non-covalent bond such as hydrogen bond, electrostatic interaction, Ï-Ï interaction, van der waal interaction. In this study, we used atomically flat mica to investigate the growth mode and the growth mechanism of
polydopamine by atomic force microscopy (AFM), x-ray photoelectron spectroscopy (XPS), and contact angle measurment. On the other hand, we also used
polydopamine-modified AFM tip to
detect the interaction with various substrates and designed surface patterning on polydimethylsiloxane (PDMS). The results show that the monolayer of
polydopamine film is completed within 300 sec and the roughness had significantly changed compared with bare mica. The
polydopamine-modified AFM tip had the strongest interaction with
Highly Oriented Pyrolytic Graphite (HOPG) due to the strong Ï-Ï interaction between the aromatic rings structure on
polydopamine and the planar structure of sp2 orbital on HOPG. Finally, the surface patterning on PDMS by
polydopamine successfully modified Au nanoparticles and Ag nanoparticles on specific area.
Advisors/Committee Members: Shang-Wu Ding (chair), Shuchen Hsieh (committee member), Huey-Shan Hung (chair).
Subjects/Keywords: patterning; AFM; polydopamine; polydimethylsiloxane; adhesion
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APA (6th Edition):
Peng, S. (2015). Investigation of Bio-Inspired Polydopamine Using Atomic Force Microscopy. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0621115-154800
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Peng, Shi-wei. “Investigation of Bio-Inspired Polydopamine Using Atomic Force Microscopy.” 2015. Thesis, NSYSU. Accessed February 28, 2021.
http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0621115-154800.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Peng, Shi-wei. “Investigation of Bio-Inspired Polydopamine Using Atomic Force Microscopy.” 2015. Web. 28 Feb 2021.
Vancouver:
Peng S. Investigation of Bio-Inspired Polydopamine Using Atomic Force Microscopy. [Internet] [Thesis]. NSYSU; 2015. [cited 2021 Feb 28].
Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0621115-154800.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Peng S. Investigation of Bio-Inspired Polydopamine Using Atomic Force Microscopy. [Thesis]. NSYSU; 2015. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0621115-154800
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Carnegie Mellon University
3.
Klosterman, Luke J.
Deposition, Oxidation, and Adhesion Mechanisms of Conformal Polydopamine Films.
Degree: 2016, Carnegie Mellon University
URL: http://repository.cmu.edu/dissertations/702
► The oxidation of dopamine in aqueous solutions deposits thin conformal films on a wide variety of material surfaces. These films consist of a material known…
(more)
▼ The oxidation of dopamine in aqueous solutions deposits thin conformal films on a wide variety of material surfaces. These films consist of a material known as polydopamine (PDA), and they exhibit chemical and structural similarities to melanin pigments and adhesive proteins secreted by mussels. The facile synthesis and versatile adhesion of PDA enable the functional modification of numerous material surfaces for applications in biomedical devices, energy storage, and water purification. This thesis details fundamental investigations into the deposition, oxidation, and adhesive mechanisms of PDA films. Depositing PDA films on substrates with different controlled chemistries revealed the importance of solution pH and initial deposition rates on the morphology of the films. The deposition of PDA molecules with increasing pH depends on two competing factors: increased generation rate of PDA molecules versus increased solubility due to catechol ionization. The areal density and coverage of three-dimensional PDA islands is influenced by the surface charge and hydrophobicity of the substrate in aqueous solutions. Spectroscopic and electrochemical characterization of PDA films revealed that redox-inactive metal cations can accelerate the oxidation of PDA. The generation of radicals of 5,6-dihydroxyindole were monitored in situ via ultraviolet-visible spectroscopy as a function of cation concentration and pH. The extent of oxidation was quantified by cyclic voltammetry. The resulting oxidation modifies the metal sorption properties of PDA by generating more carboxylic acid groups and enhancing the iron chelation of the films. The adhesive stability of PDA films was characterized by delamination kinetics of films on SiO2 and indium tin oxide (ITO). PDA film adhesion is a substrate, salt, and oxidation-dependent phenomenon. Long-term adhesive stability of PDA films can be promoted by use of higher dopamine concentrations during synthesis, incorporation of multivalent cations, and avoiding alkaline conditions and strongly oxidizing electrical bias. Elastic moduli of PDA films were quantified by compressive thin film wrinkling, and the measured value of 2.0 ± 0.9 GPA agrees with simulations of PDA based on an oligomeric aggregate model. This thesis helps develop a framework for understanding the synthesis, composition, microstructure, and stability of PDA films.
Subjects/Keywords: melanin; polydopamine; thin film
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APA (6th Edition):
Klosterman, L. J. (2016). Deposition, Oxidation, and Adhesion Mechanisms of Conformal Polydopamine Films. (Thesis). Carnegie Mellon University. Retrieved from http://repository.cmu.edu/dissertations/702
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Klosterman, Luke J. “Deposition, Oxidation, and Adhesion Mechanisms of Conformal Polydopamine Films.” 2016. Thesis, Carnegie Mellon University. Accessed February 28, 2021.
http://repository.cmu.edu/dissertations/702.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Klosterman, Luke J. “Deposition, Oxidation, and Adhesion Mechanisms of Conformal Polydopamine Films.” 2016. Web. 28 Feb 2021.
Vancouver:
Klosterman LJ. Deposition, Oxidation, and Adhesion Mechanisms of Conformal Polydopamine Films. [Internet] [Thesis]. Carnegie Mellon University; 2016. [cited 2021 Feb 28].
Available from: http://repository.cmu.edu/dissertations/702.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Klosterman LJ. Deposition, Oxidation, and Adhesion Mechanisms of Conformal Polydopamine Films. [Thesis]. Carnegie Mellon University; 2016. Available from: http://repository.cmu.edu/dissertations/702
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Ottawa
4.
Steeves, Alexander.
Physicochemical and Cellular Analysis of Polydopamine for Use as an Orthopaedic Bioadhesive
.
Degree: 2018, University of Ottawa
URL: http://hdl.handle.net/10393/38032
► Polydopamine (PDA), a unique bioinspired polymer, has been a subject of interest in fields including orthopedic biomaterials and antibacterial surfaces. Its osteogenic effects and ability…
(more)
▼ Polydopamine (PDA), a unique bioinspired polymer, has been a subject of interest in fields including orthopedic biomaterials and antibacterial surfaces. Its osteogenic effects and ability to control surface traits through precise variables (e.g., pH, temperature) have led to its use as a coating in the enhancement of a wide range of materials, including metals and ceramics. In this Thesis, two studies were carried out to better understand the capability and mechanism of PDA-mediated bioactivity. In the first study, we investigated whether PDA coatings can further enhance the bioactivity of nanoporous Titanium (NPTi). While physicochemical traits were in line with literature, PDA was effective in enhancing cell proliferation, beyond NPTi, as early as 8 hours with enhancement in cell spreading and focal adhesion prevalence as early as 1 hour. No changes in adsorptive capacity were found, suggesting a serum-independent component (SIC) of the surface. The second study was focused on (1) determining how treatment parameters influence the physiochemical makeup of PDA surfaces, (2) assessing how PDA surfaces influence stem cell behavior and (3) confirming and investigating the SIC of PDA effect. Results confirm that there is indeed a SIC of PDA coatings with enhancement in cell spreading that improves with the increased size and density of PDA particles. Our findings show that the SIC works in concert with circulating sera to elicit the bioactive effects of PDA. The novel rPDA surface, obtained by adding rotation during the coating deposition, is also shown to elevate bioactivity during normal culturing, beyond classical coatings, with ongoing work suggesting enhancement in the osteogenic differentiation of hMSCs. Taken together, this work has demonstrated novel aspects underlying the potential and mechanism of action for the bioactivity of PDA, ultimately providing new evidence supporting the use of PDA as a biomedical material.
Subjects/Keywords: biomaterial;
polydopamine;
stem cell;
titanium
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APA (6th Edition):
Steeves, A. (2018). Physicochemical and Cellular Analysis of Polydopamine for Use as an Orthopaedic Bioadhesive
. (Thesis). University of Ottawa. Retrieved from http://hdl.handle.net/10393/38032
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Steeves, Alexander. “Physicochemical and Cellular Analysis of Polydopamine for Use as an Orthopaedic Bioadhesive
.” 2018. Thesis, University of Ottawa. Accessed February 28, 2021.
http://hdl.handle.net/10393/38032.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Steeves, Alexander. “Physicochemical and Cellular Analysis of Polydopamine for Use as an Orthopaedic Bioadhesive
.” 2018. Web. 28 Feb 2021.
Vancouver:
Steeves A. Physicochemical and Cellular Analysis of Polydopamine for Use as an Orthopaedic Bioadhesive
. [Internet] [Thesis]. University of Ottawa; 2018. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/10393/38032.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Steeves A. Physicochemical and Cellular Analysis of Polydopamine for Use as an Orthopaedic Bioadhesive
. [Thesis]. University of Ottawa; 2018. Available from: http://hdl.handle.net/10393/38032
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
5.
Hertault, Adrien.
Conception et évaluation d’un stent actif pro-cicatrisant basé sur la polydopamine, un polymère biocompatible et bioinspiré : Design and evaluation of a pro-healing drug-eluting stent functionalized with polydopamine, a bioinspired and biocompatible polymer.
Degree: Docteur es, Pathologie cardiorespiratoire et vasculaire, 2019, Université Lille II – Droit et Santé
URL: http://www.theses.fr/2019LIL2S031
► Introduction : La resténose intra-stent (RIS) est induite par une prolifération incontrôlée des cellules musculaires lisses (CML) après l'implantation d'une stent métallique nu (BMS). Elle…
(more)
▼ Introduction : La resténose intra-stent (RIS) est induite par une prolifération incontrôlée des cellules musculaires lisses (CML) après l'implantation d'une stent métallique nu (BMS). Elle est associée à la récurrence des symptômes et à des coûts de santé supplémentaires. Les stents à élution médicamenteuse, dits « actifs », ont démontré leur efficacité sur la RIS, mais induisent un risque élevé de thrombose aiguë tardive due à une réendothélialisation tardive des mailles. La
polydopamine (PDA), un polymère biocompatible inspiré du mucus secrété par les moules, promouvrait la prolifération de cellules endothéliales (CE) et inhiberait la prolifération des CMV in-vitro, ce qui suggère un effet pro-cicatrisant potentiel sur la paroi vasculaire. De plus, la
polydopamine exprime des fonctions amines, catéchols et quinones à sa surface et peut être utilisée comme ancrage pour un autre agent thérapeutique. Le but de ce travail était 1) d'évaluer l'impact d'un stent enduit de PDA sur la RIS, 2) de concevoir un stent vasculaire à base de PDA délivrant une autre substance pro-cicatrisante, l'hémine.Méthodes : Dans la première partie de cette étude, les revêtements PDA étaient obtenus par immersion de disques de cobalt-chrome ou de stents dans une solution de dopamine. La biocompatibilité et l'hémocompatibilité étaient vérifiées in vitro. Le potentiel pro-cicatrisant était étudié in vitro par culture d'EC et de CML d'origine humaine sur les différents échantillons. L'effet pro-cicatrisant était étudié in-vivo après implantation de stents en position aortique chez le rat. La RIS était évaluée en microscopie optique par quantification du rapport néointima/media (n/m) après coloration éosine/hématoxilline. La qualité de la réendothélialisation des mailles était évaluée par microscopie électronique à transmission (MET). Les voies moléculaires potentiellement impliquées dans un effet pro-cicatrisant étaient étudiées par analyses Western Blot.Dans la deuxième partie de ce travail, les surfaces revêtues de PDA étaient modifiées avec de la polyéthylèneimine (PEI) pour améliorer l'expression des fonctions amines. Ce revêtement modifié était caractérisé et sa cytocompatibilité évaluée in vitro. Cette surface modifiée était ensuite utilisée pour immobiliser l'hémine. Les surfaces fonctionnalisées étaient caractérisées et la quantité d'hémine greffée déterminée. L'effet pro-cicatrisant potentiel du stent à l'hémine était évalué in vitro et in vivo.Résultats : Les surfaces de PDA démontraient un effet pro-cicatrisant in-vitro par rapport au chrome-cobalt nu. Les stents PDA montraient une réduction significative de la RIS par rapport aux stents nu (rapport n/m = 0,48 (+/- 0,26) contre 0,83 (+/- 0,42), p<0,001) dans le modèle de rat. Les analyses en TEM confirmaient la réendothélialisation des mailles dans chaque groupe et révélaient une couche de néointima plus mince dans le groupe PDA que dans le groupe BMS. Les analyses Western blot permettaient d'identifier une tendance à une activation accrue de la phosphorylation de la MAPK p38 et de…
Advisors/Committee Members: Sobocinski, Jonathan (thesis director).
Subjects/Keywords: Vasculaire; Hémine; Stent actif; Polydopamine; Drug-eluting stent; Vascular; Polydopamine; Hemin
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APA ·
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APA (6th Edition):
Hertault, A. (2019). Conception et évaluation d’un stent actif pro-cicatrisant basé sur la polydopamine, un polymère biocompatible et bioinspiré : Design and evaluation of a pro-healing drug-eluting stent functionalized with polydopamine, a bioinspired and biocompatible polymer. (Doctoral Dissertation). Université Lille II – Droit et Santé. Retrieved from http://www.theses.fr/2019LIL2S031
Chicago Manual of Style (16th Edition):
Hertault, Adrien. “Conception et évaluation d’un stent actif pro-cicatrisant basé sur la polydopamine, un polymère biocompatible et bioinspiré : Design and evaluation of a pro-healing drug-eluting stent functionalized with polydopamine, a bioinspired and biocompatible polymer.” 2019. Doctoral Dissertation, Université Lille II – Droit et Santé. Accessed February 28, 2021.
http://www.theses.fr/2019LIL2S031.
MLA Handbook (7th Edition):
Hertault, Adrien. “Conception et évaluation d’un stent actif pro-cicatrisant basé sur la polydopamine, un polymère biocompatible et bioinspiré : Design and evaluation of a pro-healing drug-eluting stent functionalized with polydopamine, a bioinspired and biocompatible polymer.” 2019. Web. 28 Feb 2021.
Vancouver:
Hertault A. Conception et évaluation d’un stent actif pro-cicatrisant basé sur la polydopamine, un polymère biocompatible et bioinspiré : Design and evaluation of a pro-healing drug-eluting stent functionalized with polydopamine, a bioinspired and biocompatible polymer. [Internet] [Doctoral dissertation]. Université Lille II – Droit et Santé 2019. [cited 2021 Feb 28].
Available from: http://www.theses.fr/2019LIL2S031.
Council of Science Editors:
Hertault A. Conception et évaluation d’un stent actif pro-cicatrisant basé sur la polydopamine, un polymère biocompatible et bioinspiré : Design and evaluation of a pro-healing drug-eluting stent functionalized with polydopamine, a bioinspired and biocompatible polymer. [Doctoral Dissertation]. Université Lille II – Droit et Santé 2019. Available from: http://www.theses.fr/2019LIL2S031
NSYSU
6.
He, Gong-chun.
In situ monitoring of the photocatalytic degradation of Methyleneblue on a Ag/PDA/[email protected] SERS substrate.
Degree: Master, Chemistry, 2016, NSYSU
URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0708116-172523
► Glass microfibers decorated with silver/
polydopamine/copper-oxide films(Ag/PDA/
[email protected]) were fabricated by a simple preparation method and their effectiveness as surface-enhanced Raman scattering (SERS) substrates evaluated using the…
(more)
▼ Glass microfibers decorated with silver/
polydopamine/copper-oxide films(Ag/PDA/
[email protected]) were fabricated by a simple preparation method and their effectiveness as surface-enhanced Raman scattering (SERS) substrates evaluated using the probe molecule Methylene Blue. Electron transfer from silver nanoparticles to CuO through the PDA film is proposed as a possible mechanism to account for the strong enhancement of SERS intensity. An enhancement value of 6.84 Ã 108 was observed, which is suitable for single molecule detection. Furthermore Ag/PDA/
[email protected] was found to degrade methylene blue in the presence of sunlight and the band gap was 2.7 eV. This confirms that Ag/PDA/
[email protected] can be excited by visible light. We used Raman spectroscopy to analyze the photocatalytic degradation reaction and further analyze the reaction intermediates and bond breaking mechanism. Our results demonstrate that Ag/PDA/
[email protected] exhibits a strong SERS enhancement during photocatalytic degradation of Methylene Blue and is a promising candidate as a more general SERS substrate.
Advisors/Committee Members: Shu-chen Hsieh (committee member), Shu-Ling Hsieh (chair), Shangwu (Sam) Ding (chair).
Subjects/Keywords: photocatalytic degradation; SERS; Glass Microfiber; Polydopamine
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APA ·
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MLA ·
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APA (6th Edition):
He, G. (2016). In situ monitoring of the photocatalytic degradation of Methyleneblue on a Ag/PDA/[email protected] SERS substrate. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0708116-172523
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
He, Gong-chun. “In situ monitoring of the photocatalytic degradation of Methyleneblue on a Ag/PDA/[email protected] SERS substrate.” 2016. Thesis, NSYSU. Accessed February 28, 2021.
http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0708116-172523.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
He, Gong-chun. “In situ monitoring of the photocatalytic degradation of Methyleneblue on a Ag/PDA/[email protected] SERS substrate.” 2016. Web. 28 Feb 2021.
Vancouver:
He G. In situ monitoring of the photocatalytic degradation of Methyleneblue on a Ag/PDA/[email protected] SERS substrate. [Internet] [Thesis]. NSYSU; 2016. [cited 2021 Feb 28].
Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0708116-172523.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
He G. In situ monitoring of the photocatalytic degradation of Methyleneblue on a Ag/PDA/[email protected] SERS substrate. [Thesis]. NSYSU; 2016. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0708116-172523
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Manitoba
7.
Zhang, Xingying.
Conductive materials for tissue engineering and health monitoring systems.
Degree: Mechanical Engineering, 2020, University of Manitoba
URL: http://hdl.handle.net/1993/34681
► Two strategies were used in this thesis to repair muscle tissues that require electrical stimulus: replacing the 3D polymeric scaffold with a novel conductive material—a…
(more)
▼ Two strategies were used in this thesis to repair muscle tissues that require electrical stimulus: replacing the 3D polymeric scaffold with a novel conductive material—a reduced rGO aerogel modified by PTA coating and PDA coating; and coating the non-conductive polymeric scaffold with conductive coating—ppy. To fabricate an ultra-soft, ultra-thin, multifunctional, and yet
subject to large scalability health monitoring system, a “masked spin coating” process was used. The as-fabricated patterned GO/rGO structure can work as not only MHMS but also a humidity responsive actuator.
Advisors/Committee Members: Xing, Malcolm (Mechanical Engineering) (supervisor), Deng, Chuang (Mechanical Engineering).
Subjects/Keywords: tissue engineering; sensor; aerogel; graphene; polypyrrole; polydopamine
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APA (6th Edition):
Zhang, X. (2020). Conductive materials for tissue engineering and health monitoring systems. (Masters Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/34681
Chicago Manual of Style (16th Edition):
Zhang, Xingying. “Conductive materials for tissue engineering and health monitoring systems.” 2020. Masters Thesis, University of Manitoba. Accessed February 28, 2021.
http://hdl.handle.net/1993/34681.
MLA Handbook (7th Edition):
Zhang, Xingying. “Conductive materials for tissue engineering and health monitoring systems.” 2020. Web. 28 Feb 2021.
Vancouver:
Zhang X. Conductive materials for tissue engineering and health monitoring systems. [Internet] [Masters thesis]. University of Manitoba; 2020. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/1993/34681.
Council of Science Editors:
Zhang X. Conductive materials for tissue engineering and health monitoring systems. [Masters Thesis]. University of Manitoba; 2020. Available from: http://hdl.handle.net/1993/34681
University of Texas – Austin
8.
Miller, Daniel Joseph Lang.
Assessment of fouling in native and surface-modified water purification membranes.
Degree: PhD, Chemical Engineering, 2013, University of Texas – Austin
URL: http://hdl.handle.net/2152/25182
► Fouling is a major obstacle to the implementation of membranes in water purification applications. Hydrophilization of the membrane surface tends to mitigate fouling because hydrophobic…
(more)
▼ Fouling is a major obstacle to the implementation of membranes in water purification applications. Hydrophilization of the membrane surface tends to mitigate fouling because hydrophobic interactions between foulants and the membrane are reduced.
Polydopamine was deposited onto membranes to render their surfaces hydrophilic. The chemical structure of
polydopamine, which was previously ambiguous, was investigated by many spectroscopic techniques. While previously thought to consist of covalently-linked monomers,
polydopamine was found to be an aggregate of partly-oxidized dopamine units linked by strong, non-covalent secondary interactions.
Polydopamine was also used as a platform for the molecular conjugation of other anti-fouling materials, such as poly(ethylene glycol), to the membrane surface. Membrane fouling was assessed by constant permeate flux crossflow filtration with an oil/water emulsion feed. The threshold flux – the flux at which the rate of fouling significantly increases – was determined by a well-established flux stepping technique. Membrane resistance evolution during fouling was compared for constant flux and constant transmembrane pressure operation using unmodified membranes. Below the threshold flux (slow fouling), good agreement in resistance evolution was found between the two operational modes; above the threshold flux, significant deviation was observed. The effect of
polydopamine and
polydopamine-g-poly(ethylene glycol) surface modifications was studied under constant flux crossflow fouling conditions. The surface modifications were found to increase the membrane resistance, resulting in higher transmembrane pressures in the modified membranes than in the unmodified membranes at fluxes below the threshold flux. Modified membranes were also compared to unmodified membranes with the same pure water permeance (same initial resistance). In this case, the modified membranes had lower transmembrane pressures during fouling than the unmodified membranes, suggesting that a preferred method of membrane surface modification is to begin with a membrane of higher permeance than required, and then surface-modify it to achieve the desired permeance. The efficacy of
polydopamine and
polydopamine-g-poly(ethylene glycol) surface modifications in reducing biofouling was also evaluated. Modified membranes showed reduced protein and bacterial adhesion in short-term tests, which are commonly used to assess biofouling propensity. However, long-term operation under hydrodynamic conditions mimicking those of an industrial module showed no benefit of the hydrophilic coatings in limiting biofouling.
Advisors/Committee Members: Freeman, B. D. (Benny D.) (advisor), Paul, Donald R. (advisor).
Subjects/Keywords: Membrane; Fouling; Polydopamine; Water purification; Ultrafiltration
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APA (6th Edition):
Miller, D. J. L. (2013). Assessment of fouling in native and surface-modified water purification membranes. (Doctoral Dissertation). University of Texas – Austin. Retrieved from http://hdl.handle.net/2152/25182
Chicago Manual of Style (16th Edition):
Miller, Daniel Joseph Lang. “Assessment of fouling in native and surface-modified water purification membranes.” 2013. Doctoral Dissertation, University of Texas – Austin. Accessed February 28, 2021.
http://hdl.handle.net/2152/25182.
MLA Handbook (7th Edition):
Miller, Daniel Joseph Lang. “Assessment of fouling in native and surface-modified water purification membranes.” 2013. Web. 28 Feb 2021.
Vancouver:
Miller DJL. Assessment of fouling in native and surface-modified water purification membranes. [Internet] [Doctoral dissertation]. University of Texas – Austin; 2013. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/2152/25182.
Council of Science Editors:
Miller DJL. Assessment of fouling in native and surface-modified water purification membranes. [Doctoral Dissertation]. University of Texas – Austin; 2013. Available from: http://hdl.handle.net/2152/25182
9.
Ponzio, Florian.
Synthesis at different interfaces of bio-inspired films from mussels' byssus : influence of the oxidant nature at the solid/liquid interface and the addition of polymer at the air/water interface : Synthèse à différentes interfaces de films bio-inspirés du byssus de la moule : Influence de la nature de l'oxydant à l'interface solide-liquide et d'ajout de polymères à l'interface air-eau.
Degree: Docteur es, Chimie physique, 2016, Université de Strasbourg
URL: http://www.theses.fr/2016STRAE041
► Les matériaux à base de polydopamine (PDA) s’inspirent de la forte adhésion du byssus de la moule sous l’eau. L’oligomérisation de la dopamine dans un…
(more)
▼ Les matériaux à base de polydopamine (PDA) s’inspirent de la forte adhésion du byssus de la moule sous l’eau. L’oligomérisation de la dopamine dans un milieu basique permet la formation de revêtement de PDA sur n’importe quel matériau. En plus de la simplicité du procédé celui-ci est vert et versatile. La PDA a des propriétés similaires aux mélanines, d’où son utilisation dans le domaine des phénomènes de conversion d’énergie, de l’environnement et du biomédical. Cependant la structure de la PDA étant inconnue, l’élaboration de matériaux basés sur la relation structure propriétés est difficile. L’un des buts de cette thèse a été de comprendre cette relation pour élaborer de nouveaux matériaux de PDA. En choisissant l’oxydant adéquat nous avons déposé un film épais, superhydrophile et biocompatible sur n’importe quels substrats. De plus nous avons découverts la possibilité de former des films de PDA à l’interface air/eau. L’étude de ce phénomène a permis de former des membranes autosupportées et stimuli responsives.
Polydopamine (PDA) materials are inspired from mussels’ byssus strong adhesion underwater. The oligomerization of dopamine in a basic medium allows forming a PDA coating on virtually any materials. In addition to the simplicity, ecofriendly and versatility of the deposition method, PDA has properties similar to those of melanin pigments and displays many outstanding properties. Thus PDAis widely used in energy, environmental and biomedical sciences. However design of PDA based new materials with tailored properties is a challenge since its structure is still unknown. In that sense one of the aims of this thesis is to gain knowledge in PDA structure-property relationship in order to design PDA materials with new properties. By choosing the appropriate oxidant we deposited thick and superhydrophylic films on any materials for the elaboration of low fouling and biocompatible surfaces. Additionally we discovered the possibility to form PDA films at the air/water interface. The investigation of this phenomenon led to the formation of stimuli responsive free standing membranes.
Advisors/Committee Members: Ball, Vincent (thesis director).
Subjects/Keywords: Polydopamine; Films minces; Mécanisme réactionel; Superhydrophilie; Biomimétisme; Matériaux stimuli responsifs; Polydopamine; Thin films; Reaction mechanism; Superhydrophilicity; Biomimetism; Stimuli responsive materials; 541.3
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APA (6th Edition):
Ponzio, F. (2016). Synthesis at different interfaces of bio-inspired films from mussels' byssus : influence of the oxidant nature at the solid/liquid interface and the addition of polymer at the air/water interface : Synthèse à différentes interfaces de films bio-inspirés du byssus de la moule : Influence de la nature de l'oxydant à l'interface solide-liquide et d'ajout de polymères à l'interface air-eau. (Doctoral Dissertation). Université de Strasbourg. Retrieved from http://www.theses.fr/2016STRAE041
Chicago Manual of Style (16th Edition):
Ponzio, Florian. “Synthesis at different interfaces of bio-inspired films from mussels' byssus : influence of the oxidant nature at the solid/liquid interface and the addition of polymer at the air/water interface : Synthèse à différentes interfaces de films bio-inspirés du byssus de la moule : Influence de la nature de l'oxydant à l'interface solide-liquide et d'ajout de polymères à l'interface air-eau.” 2016. Doctoral Dissertation, Université de Strasbourg. Accessed February 28, 2021.
http://www.theses.fr/2016STRAE041.
MLA Handbook (7th Edition):
Ponzio, Florian. “Synthesis at different interfaces of bio-inspired films from mussels' byssus : influence of the oxidant nature at the solid/liquid interface and the addition of polymer at the air/water interface : Synthèse à différentes interfaces de films bio-inspirés du byssus de la moule : Influence de la nature de l'oxydant à l'interface solide-liquide et d'ajout de polymères à l'interface air-eau.” 2016. Web. 28 Feb 2021.
Vancouver:
Ponzio F. Synthesis at different interfaces of bio-inspired films from mussels' byssus : influence of the oxidant nature at the solid/liquid interface and the addition of polymer at the air/water interface : Synthèse à différentes interfaces de films bio-inspirés du byssus de la moule : Influence de la nature de l'oxydant à l'interface solide-liquide et d'ajout de polymères à l'interface air-eau. [Internet] [Doctoral dissertation]. Université de Strasbourg; 2016. [cited 2021 Feb 28].
Available from: http://www.theses.fr/2016STRAE041.
Council of Science Editors:
Ponzio F. Synthesis at different interfaces of bio-inspired films from mussels' byssus : influence of the oxidant nature at the solid/liquid interface and the addition of polymer at the air/water interface : Synthèse à différentes interfaces de films bio-inspirés du byssus de la moule : Influence de la nature de l'oxydant à l'interface solide-liquide et d'ajout de polymères à l'interface air-eau. [Doctoral Dissertation]. Université de Strasbourg; 2016. Available from: http://www.theses.fr/2016STRAE041
10.
Lefebvre, Louis.
Développement et caractérisation de mousses cellulaires élastomères pour l’intensification des procédés : Development and characterization of Open Cell Polyurethane Foam for process intensification.
Degree: Docteur es, Génie des procédés, 2019, Lyon
URL: http://www.theses.fr/2019LYSE1028
► Les mousses solides, en polyuréthane, sont connues pour avoir des propriétés de transports intéressantes telles que des faibles pertes de charges engendrées ou une grande…
(more)
▼ Les mousses solides, en polyuréthane, sont connues pour avoir des propriétés de transports intéressantes telles que des faibles pertes de charges engendrées ou une grande surface spécifique développée permettant une bonne évacuation de la chaleur. Cependant, elles ne sont pas utilisées en tant que support catalytique à cause des méthodes de déposition actuelles qui provoquent une altération de leurs propriétés mécaniques. Nous avons tout d’abord utilisé une nouvelle méthode de déposition basée sur la polydopamine(PDA), un polymère aux propriétés intéressantes, d’adhésion et de réduction. La PDA va venir recouvrir de manière homogène notre support puis va servir d’intermédiaire pour le dépôt de différentes phases active, qu’elles soient commerciales ou synthétisées in-situ. Par la suite, nos supports ont été employés dans plusieurs réactions, qu’elles soient monophasiques (liquide) ou bi-phasiques (gaz/liquide), afin de mettre en avant l’efficacité et la stabilité du dépôt de nos phases actives. De plus, il nous a été possible de déposer une phase active intéressante pour la production d’hydrogène. L’étude cinétique de cette réaction à basse température a été réalisée et a montré des résultats prometteurs pour le domaine des énergies renouvelables. Enfin, la dernière partie est consacrée à la mise en place de notre support structuré au sein d’un réacteur innovant, permettant d’utiliser les propriétés mécaniques du dit support afin d’améliorer les propriétés de transfert de matière
Solid foams, made with polyurethane, are well known for their interesting transport properties such as low pressure drop or high specific surface area. However, there are not used as catalytic support due to actual deposition method which causes an alteration of their mechanical properties. First, we used a new deposition method using polydopamine (PDA), a polymer with interesting adhesive and reducing properties. The PDA layer will cover homogenously our support then will act as intermediary for active phase deposition, whether they are commercially available or synthetized in-situ. Afterward, our supports were tested for several catalytic reactions, whether monophasic (liquid phase) or biphasic (gas/liquid) to show the active phase efficiency and stability. Furthermore, we successfully deposited a good active phase (cobalt) for hydrogen production. Kinetic study at low temperature were done and shown promising results for sustainable energy production. Finally, the last part was devoted to the use of our soft structured catalytic support within a new reactor, allowing to use its mechanical properties to improve mass transfer
Advisors/Committee Members: Edouard, David (thesis director), Tayakout, Mélaz (thesis director).
Subjects/Keywords: Mousse de polyuréthane; Polydopamine; Fonctionnalisation; Support catalytique structuré souple; Polyurethane foam; Polydopamine; Functionalization; Soft Structured Catalytic Support (S2CS); 660
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APA (6th Edition):
Lefebvre, L. (2019). Développement et caractérisation de mousses cellulaires élastomères pour l’intensification des procédés : Development and characterization of Open Cell Polyurethane Foam for process intensification. (Doctoral Dissertation). Lyon. Retrieved from http://www.theses.fr/2019LYSE1028
Chicago Manual of Style (16th Edition):
Lefebvre, Louis. “Développement et caractérisation de mousses cellulaires élastomères pour l’intensification des procédés : Development and characterization of Open Cell Polyurethane Foam for process intensification.” 2019. Doctoral Dissertation, Lyon. Accessed February 28, 2021.
http://www.theses.fr/2019LYSE1028.
MLA Handbook (7th Edition):
Lefebvre, Louis. “Développement et caractérisation de mousses cellulaires élastomères pour l’intensification des procédés : Development and characterization of Open Cell Polyurethane Foam for process intensification.” 2019. Web. 28 Feb 2021.
Vancouver:
Lefebvre L. Développement et caractérisation de mousses cellulaires élastomères pour l’intensification des procédés : Development and characterization of Open Cell Polyurethane Foam for process intensification. [Internet] [Doctoral dissertation]. Lyon; 2019. [cited 2021 Feb 28].
Available from: http://www.theses.fr/2019LYSE1028.
Council of Science Editors:
Lefebvre L. Développement et caractérisation de mousses cellulaires élastomères pour l’intensification des procédés : Development and characterization of Open Cell Polyurethane Foam for process intensification. [Doctoral Dissertation]. Lyon; 2019. Available from: http://www.theses.fr/2019LYSE1028
11.
Lacreuse, Isabelle.
Contributions à l’amélioration et l’élaboration de biomateriaux dédiés à la hernie diaphragmatique congénitale : Contributions to the improvement and elaboration of biomaterials dedicated to the congenital diaphragmatic hernia.
Degree: Docteur es, Chimie physique, 2019, Université de Strasbourg
URL: http://www.theses.fr/2019STRAE014
► La hernie diaphragmatique congénitale se définit par la présence d’un défect postérolatéral du muscle diaphragmatique. Sa prise en charge est chirurgicale par interposition d’une prothèse…
(more)
▼ La hernie diaphragmatique congénitale se définit par la présence d’un défect postérolatéral du muscle diaphragmatique. Sa prise en charge est chirurgicale par interposition d’une prothèse dans les formes les plus graves. La prothèse idéale n’existe pas et nous l’avons prouvé par l’analyse d’explants montrant une colonisation non satisfaisante. De même les tests mécaniques réalisés sur les prothèses les plus couramment utilisées montrent des propriétés inadaptées dans cette indication. Nous avons pu développer deux axes prometteurs :- La fonctionnalisation par la polydopamine du Tétrafluoroethylène expansé améliore les propriétés biologiques de la prothèse sans altérer sa structure.- Nous avons su développer un matériau innovant, biface dont les propriétés mécaniques répondent au cahier des charges d’une prothèse diaphragmatique implantée en période néonatale par une meilleure élasticité. Par ailleurs, les premiers tests in vitro montrent une colonisation importante du matériau in vitro avec une meilleure adhésion cellulaire au sein de sa trame. Ces éléments nous poussent à poursuivre les investigations vers des tests complémentaires pour aller vers un matériau brevetable.
Congenital diaphragmatic hernia is defined by the presence of posterolateral dysfunction of the diaphragmatic muscle. Its management is surgical by interposition of a prosthesis in the most serious forms. The ideal prosthesis does not exist and we have proved it by explant analysis showing unsatisfactory colonization. Similarly, the mechanical tests performed on the most commonly used prostheses show properties that are unsuitable for this indication. We have been able to develop two promising areas : the functionalization with polydopamine of expanded tetrafluoroethylene improves the biological properties of the prosthesis without altering its structure. We have developed an innovative material, whose mechanical properties meet the specifications of a diaphragmatic prosthesis implanted in the neonatal period by a better elasticity. In addition, the first in vitro tests show a significant colonization of the material in vitro with better cell adhesion within its frame. These elements push us to continue the investigations towards additional tests to go towards a patentable material.
Advisors/Committee Members: Hemmerlé, Joseph (thesis director), Frisch, Benoît (thesis director).
Subjects/Keywords: Hernie diaphragmatique congénitale; E-PTFE; Polydopamine; TPU; Prothèse; Diaphragmatic hernia; E-PTFE; Polydopamine; TPU; 617.547; 571.43
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APA ·
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APA (6th Edition):
Lacreuse, I. (2019). Contributions à l’amélioration et l’élaboration de biomateriaux dédiés à la hernie diaphragmatique congénitale : Contributions to the improvement and elaboration of biomaterials dedicated to the congenital diaphragmatic hernia. (Doctoral Dissertation). Université de Strasbourg. Retrieved from http://www.theses.fr/2019STRAE014
Chicago Manual of Style (16th Edition):
Lacreuse, Isabelle. “Contributions à l’amélioration et l’élaboration de biomateriaux dédiés à la hernie diaphragmatique congénitale : Contributions to the improvement and elaboration of biomaterials dedicated to the congenital diaphragmatic hernia.” 2019. Doctoral Dissertation, Université de Strasbourg. Accessed February 28, 2021.
http://www.theses.fr/2019STRAE014.
MLA Handbook (7th Edition):
Lacreuse, Isabelle. “Contributions à l’amélioration et l’élaboration de biomateriaux dédiés à la hernie diaphragmatique congénitale : Contributions to the improvement and elaboration of biomaterials dedicated to the congenital diaphragmatic hernia.” 2019. Web. 28 Feb 2021.
Vancouver:
Lacreuse I. Contributions à l’amélioration et l’élaboration de biomateriaux dédiés à la hernie diaphragmatique congénitale : Contributions to the improvement and elaboration of biomaterials dedicated to the congenital diaphragmatic hernia. [Internet] [Doctoral dissertation]. Université de Strasbourg; 2019. [cited 2021 Feb 28].
Available from: http://www.theses.fr/2019STRAE014.
Council of Science Editors:
Lacreuse I. Contributions à l’amélioration et l’élaboration de biomateriaux dédiés à la hernie diaphragmatique congénitale : Contributions to the improvement and elaboration of biomaterials dedicated to the congenital diaphragmatic hernia. [Doctoral Dissertation]. Université de Strasbourg; 2019. Available from: http://www.theses.fr/2019STRAE014
NSYSU
12.
Chen, Jyun-de.
Fabrication of metal-semiconductor materials by polydopamine and its application in SERS.
Degree: Master, Chemistry, 2016, NSYSU
URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0704116-111522
► Surface-Enhanced Raman Spectroscopy ( SERS ) has broad applications in the fields of biology, medicine and chemistry due to high sensitivity, high resolution and high…
(more)
▼ Surface-Enhanced Raman Spectroscopy ( SERS ) has broad applications in the fields of biology, medicine and chemistry due to high sensitivity, high resolution and high selectivity to the adsorbate. In recent years, it was reported that materials combining metal and semiconductor can greatly increase the SERS enhancement effect. In this experiment, we synthesized Ag/PDA/
[email protected] which combined metal and semiconductor using
polydopamine, and had the benefits of being environmentally friendly, exhibiting good adsorption, and being a strong reductant. We applied the material to SERS and found that the SERS enhancement effect increased significantly, making it an attractive SERS substrate. We observed that the material exhibited the rod-stacking structure by SEM. We performed qualitative and quantitative analysis of the material by XRD, EDS and ICP-MS. From the results of XPS, we observed the charge transfer effect between the silver nanoparticles and zinc oxide, which explains the increased SERS enhancement effect. By tuning the deposition time of the silver nanoparticles, we tested the detection limit of Rhodamine B and monitored the photocatalytic degradation. We found that the best condition of deposition time was 8hr, and the photocatalytic degradation was first-order reaction. Because the material possessed both high sensitivity of SERS and catalytic activity of reaction, we repeated the experiment in five times on the substrate of best condition. We found that the substrate could maintain considerable catalytic activity, appropriate for serving as recyclable sensing material. It would have good prospect to apply to the trace sensing of organic pollutants and fabricating the SERS substrate which could be the catalyst.
Advisors/Committee Members: Shu-chen Hsieh (committee member), Shu-chen Hsieh (chair), Shang-Wu Ding (chair), Shu-Ling Hsieh (chair).
Subjects/Keywords: zinc oxide; reductant; polydopamine; silver nanoparticles; Surface-Enhanced Raman Spectroscopy
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APA ·
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APA (6th Edition):
Chen, J. (2016). Fabrication of metal-semiconductor materials by polydopamine and its application in SERS. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0704116-111522
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Chen, Jyun-de. “Fabrication of metal-semiconductor materials by polydopamine and its application in SERS.” 2016. Thesis, NSYSU. Accessed February 28, 2021.
http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0704116-111522.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Chen, Jyun-de. “Fabrication of metal-semiconductor materials by polydopamine and its application in SERS.” 2016. Web. 28 Feb 2021.
Vancouver:
Chen J. Fabrication of metal-semiconductor materials by polydopamine and its application in SERS. [Internet] [Thesis]. NSYSU; 2016. [cited 2021 Feb 28].
Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0704116-111522.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Chen J. Fabrication of metal-semiconductor materials by polydopamine and its application in SERS. [Thesis]. NSYSU; 2016. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0704116-111522
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
NSYSU
13.
Li, Jun-sian.
The preparation of CaO nanoparticles and heavy metals adsorbent using Oyster Shells as green chemical source.
Degree: Master, Chemistry, 2017, NSYSU
URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0607117-160732
► In recent years, concern for the environment and interest in sustainable development has risen dramatically. Modern researchers now attempt to find solutions to difficult technical…
(more)
▼ In recent years, concern for the environment and interest in sustainable development has risen dramatically. Modern researchers now attempt to find solutions to difficult technical challenges using "green chemistry" processes and renewable materials. In this study, we use Oyster shell as a âgreenâ or natural material source to prepare three materials for use in several applications. This study is divided into two parts. In part 1, we prepared spherical calcium oxide nanoparticles (CaO-NPs) by hydrothermal synthesis in a sealed pressure vessel with water as the solvent. X-ray diffraction (XRD) was used to characterize the structure and transmission electron microscopy (TEM) to observe the CaO-NPs morphology. The CaO-NPs were approximately 40 nm in diameter and had a uniform dispersion. Additionally, we prepared silver/
polydopamine/calcium-oxide (Ag/PDA/CaO) samples for use as surface-enhanced Raman scattering (SERS) substrates and evaluated them using the probe molecule 4-aminothiophenil (4-ATP). Ag/PDA/CaO enhanced the 4-ATP signal and increased the detection limit up to 10-8 M. In part 2 of our study, we prepared Vaterite particles from oyster shell and tested their removal efficiency for different heavy metal ions. The results showed the removal efficiency was Pb2+ (99.9%), Cr3+ (99.5%), Fe3+ (99.3%) and Cu2+ (57.1%). We speculate that the ion exchange reaction between calcium ions and metal ions produces recrystallization which further affects the removal efficiency. Furthermore, the BET (Brunauer-Emmett-Teller) model shows that Vaterite particles are a giant pore adsorbent material that can rapidly adsorb large amounts of metal ions. In addition to the high efficiency heavy metal ion removal, the Vaterite particles are cheap and easy to synthesize (69% yield), thus providing a low cost and efficient alternative for industrial wastewater remediation.
Advisors/Committee Members: Chih-chung Wu (chair), Shu-ling Hsieh (chair), Shu-chen Hsieh (committee member).
Subjects/Keywords: CaO-NPs; CaCO3; silver nanoparticles; polydopamine; SERS; Oyster shell
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Li, J. (2017). The preparation of CaO nanoparticles and heavy metals adsorbent using Oyster Shells as green chemical source. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0607117-160732
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Li, Jun-sian. “The preparation of CaO nanoparticles and heavy metals adsorbent using Oyster Shells as green chemical source.” 2017. Thesis, NSYSU. Accessed February 28, 2021.
http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0607117-160732.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Li, Jun-sian. “The preparation of CaO nanoparticles and heavy metals adsorbent using Oyster Shells as green chemical source.” 2017. Web. 28 Feb 2021.
Vancouver:
Li J. The preparation of CaO nanoparticles and heavy metals adsorbent using Oyster Shells as green chemical source. [Internet] [Thesis]. NSYSU; 2017. [cited 2021 Feb 28].
Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0607117-160732.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Li J. The preparation of CaO nanoparticles and heavy metals adsorbent using Oyster Shells as green chemical source. [Thesis]. NSYSU; 2017. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0607117-160732
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of California – San Diego
14.
Huang, Yuran.
Multifunctional Polymeric Materials Programming Interfaces and Designed Artificial Melanosomes.
Degree: Materials Sci and Engineering, 2017, University of California – San Diego
URL: http://www.escholarship.org/uc/item/24n8t5ng
► The interfaces with micro/nanostructures in nature play important roles to bring in specific functions, which inspired and drove the development of novel nanostructures, including inorganic…
(more)
▼ The interfaces with micro/nanostructures in nature play important roles to bring in specific functions, which inspired and drove the development of novel nanostructures, including inorganic nanoparticles and organic nanoparticles. Among them, polymeric nanoparticles have been widely explored to programming interfaces because of the precise controlling in synthesis of polymers. Ring opening metathesis polymerization (ROMP) is a unique polymerization technique, which can incorporate versatile functional groups, tunable composition (hydrophobicity, molecular weight), and stimuli-responsiveness to endow various functionalities for the polymers, which have been explored for different application areas. In our research, we focused on designing and synthesizing multifunctional ROMP-based polymeric materials programming interfaces for different applications. For Chapter 2, we describe amphiphilic tri-block copolymers containing FeIII-catecholate complexes formulated as spherical- or cylindrical-shaped micellar nanoparticles (SMN and CMN respectively) as new T1-weighted agents with high relaxivity, low cytotoxicity, and long-term stability in biological fluids. Relaxivities of both SMN and CMN exceed those of established gadolinium chelates across a wide range of magnetic field strengths. Interestingly, shape-dependent behavior was observed in terms of the particles’ interactions with HeLa cells, with CMN exhibiting enhanced uptake and contrast via magnetic resonance imaging (MRI) compared with SMN. These results suggest that control over soft nanoparticle shape will provide an avenue for optimization of particle based contrast agents as biodiagnostics. We propose those polycatechol nanoparticles as suitable for pre-clinical investigations into their viability as gadolinium-free, safe and effective imaging agents for MRI contrast enhancement. For Chapter 3, we describe a method for the stabilization of low-boiling point (low-bp) perfluorocarbons (PFCs) at physiological temperatures by an amphiphilic triblock copolymer which can emulsify PFCs and be crosslinked. After UV-induced thiol-ene crosslinking, the core of the PFC emulsion remains in liquid form even at temperatures exceeding their boiling points. Critically, the formulation permits vaporization at rarefactional pressures relevant for clinical ultrasound. For Chapter 4, liquid crystals confined within micrometer-scale domains have been explored as the basis of a wide range of field- and stimuli-responsive materials for use in technologies spanning from biological sensors to electro-optical devices. We aim to build up a versatile stimuli-responsive polymeric surfactant to modulate the orientation of liquid crystal microdroplets. By incorporated different types of cleavable linkers into this system, we are able to endow versatile stimuli-responsiveness (UV, Redox, pH, ROS) in order to adapt to different certain circumstances. We proved that those cleavable linker-contained homopolymers were able to emulsify with liquid crystal droplets and generate radial…
Subjects/Keywords: Materials Science; Contrast agents; Imaging; Nanomaterials; polydopamine; Polymer
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APA (6th Edition):
Huang, Y. (2017). Multifunctional Polymeric Materials Programming Interfaces and Designed Artificial Melanosomes. (Thesis). University of California – San Diego. Retrieved from http://www.escholarship.org/uc/item/24n8t5ng
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Huang, Yuran. “Multifunctional Polymeric Materials Programming Interfaces and Designed Artificial Melanosomes.” 2017. Thesis, University of California – San Diego. Accessed February 28, 2021.
http://www.escholarship.org/uc/item/24n8t5ng.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Huang, Yuran. “Multifunctional Polymeric Materials Programming Interfaces and Designed Artificial Melanosomes.” 2017. Web. 28 Feb 2021.
Vancouver:
Huang Y. Multifunctional Polymeric Materials Programming Interfaces and Designed Artificial Melanosomes. [Internet] [Thesis]. University of California – San Diego; 2017. [cited 2021 Feb 28].
Available from: http://www.escholarship.org/uc/item/24n8t5ng.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Huang Y. Multifunctional Polymeric Materials Programming Interfaces and Designed Artificial Melanosomes. [Thesis]. University of California – San Diego; 2017. Available from: http://www.escholarship.org/uc/item/24n8t5ng
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of California – San Diego
15.
Wang, Zhao.
Artificial Melanin: From Synthesis to Chemical Properties and Applications.
Degree: Chemistry, 2018, University of California – San Diego
URL: http://www.escholarship.org/uc/item/0w56j817
► Melanins are a class of naturally occurring pigments found throughout nature. They have gained great attention because it has a unique combination of properties functions…
(more)
▼ Melanins are a class of naturally occurring pigments found throughout nature. They have gained great attention because it has a unique combination of properties functions from metal ion chelation, photoprotection, free radical quenching, and coloration. We apply the synthetic chemistry combined with our increasing understanding of the natural systems to target, control, combine, and enhance the functionality of natural melanin, far beyond their natural capabilities. We term these nanostructures “Artificial Melanin”. Polydopamine (PDA), one type of synthetic melanin, reproduces essential properties of natural melanin. For example, PDA displays a keen ability to chelate various metal ions, making it a promising material for a wide range of applications, including in bioimaging, surface modification, electrocatalysis, batteries, and biosensing. We demonstrate that the introduction of metal to PDA can allow us to understand the effect of the spin centers towards the magnetic relaxation properties of a surrounding medium. These findings offer a guide to design more efficient contrast agents. For Chapter 2, we employ a synthetic method for drastically increasing and controlling the iron loading of artificial melanin particles to perform a quantitative investigation on the structure-property relationship by using a family of Fe(III)-chelated polydopamine nanoparticles doped with a tunable concentration of Fe(III) ions. A comprehensive analysis by magnetometry, electron paramagnetic resonance (EPR), and nuclear magnetic resonance dispersion (NMRD) demonstrates that the population of isolated Fe(III) centers dictates the degree of MRI contrast. These analyses allow prediction of the optimal Fe(III) loading via a quantitative modeling of antiferromagnetic coupling. These conclusions not only offer an intuitive understanding of the atomic origins of MRI contrast in complex polycatechol nanoparticles but also suggest future directions for the development of new enhanced MRI contrast agents. For Chapter 3, we synthesize metal-loaded polydopamine nanoparticles via autoxidation polymerization of dopamine in the presence of metal-dopamine complexes. Various metal ions including Mn(III), Fe(III), Co(II), Ni(II), Cu(II), Zn(II), and Ga(III) ions could be incorporated into these artificial melanin nanoparticles with this strategy. We perform analysis on the doping range and parameters that affect the particles’ morphology. An investigation by magnetometry reveals general electronic structure and interactions for artificial melanin nanoparticles doped with Mn(III), Ni(II) and Co(II) ions. In addition, we compare the magnetic properties of high Mn(III)-loaded nanoparticles with Fe(III)-loaded nanoparticles to assess their potential as MRI contrast agents. For Chapter 4, we report the preparation artificial melanin nanoparticles with tunable Gadolinium loadings. These nanoparticles are analyzed by NMRD and with a 7 T magnetic resonance imaging (MRI) scanner. We observed a relaxivity of 75 mM−1 s −1 and 10.3 mM−1 s −1 at 1.4 T…
Subjects/Keywords: Chemistry; antiferromagnetic coupling; Melanin; Metal Coordination; MRI; Polydopamine; Relaxivity
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APA ·
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APA (6th Edition):
Wang, Z. (2018). Artificial Melanin: From Synthesis to Chemical Properties and Applications. (Thesis). University of California – San Diego. Retrieved from http://www.escholarship.org/uc/item/0w56j817
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Wang, Zhao. “Artificial Melanin: From Synthesis to Chemical Properties and Applications.” 2018. Thesis, University of California – San Diego. Accessed February 28, 2021.
http://www.escholarship.org/uc/item/0w56j817.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Wang, Zhao. “Artificial Melanin: From Synthesis to Chemical Properties and Applications.” 2018. Web. 28 Feb 2021.
Vancouver:
Wang Z. Artificial Melanin: From Synthesis to Chemical Properties and Applications. [Internet] [Thesis]. University of California – San Diego; 2018. [cited 2021 Feb 28].
Available from: http://www.escholarship.org/uc/item/0w56j817.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Wang Z. Artificial Melanin: From Synthesis to Chemical Properties and Applications. [Thesis]. University of California – San Diego; 2018. Available from: http://www.escholarship.org/uc/item/0w56j817
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Connecticut
16.
Russo, Jonathan L.
Inhibition of Urinary Tract Infections and Biofilm Formation on Long-term Indwelling Urethral Catheters through Antibacterial Coatings.
Degree: M. Eng., Biomedical Engineering, 2014, University of Connecticut
URL: https://opencommons.uconn.edu/gs_theses/573
► Indwelling urethral catheters are both important and convenient biomedical devices for many people. They provide incontinent and/or paraplegic patients an involuntary method of emptying…
(more)
▼ Indwelling urethral catheters are both important and convenient biomedical devices for many people. They provide incontinent and/or paraplegic patients an involuntary method of emptying their bladder. The catheters are inserted through the patient’s urethra to the posterior portion of the bladder. A balloon is inflated with water to keep it secure and in place. The tip of the catheter has an eye hole exposing the lumen of the catheter. The urine in the bladder drains through the lumen and out of the body into a collection bag. Catheters can potentially have 2 problems. First, they are prone to calcium/magnesium phosphate buildup on the surface and lumen of the catheter. This could obstruct the flow of urine making emptying the bladder difficult or impossible. Buildup on the surface of the catheter could also make removal of the catheter painful or even impossible without surgery. Secondly, catheters provide bacteria a route to travel to the kidneys to cause urinary tract infections. This could lead to long term problems such as chronic kidney disease.
The primary culprit for these infections is the bacterium
Proteus mirabilis. This bacteria has the ability to swarm on the catheter surface and travel to the bladder. It then secretes an enzyme called urease. This enzyme catalyzes a hydrolysis reaction converting urea into ammonia which eventually leads to nucleation of calcium and magnesium phosphate which can adhere to the catheter. The bacteria then differentiates into a swarmer bacteria and travels along the catheter surface to the kidneys where it causes urinary tract infections. The bacteria can easily adhere to hydrophilic surfaces and express factors to adhere to hydrophobic surfaces.
This research will aim to prevent these problems through the use of antibacterial coatings on the surface and lumen of the catheters. Different techniques were tested such as disrupting the bacterial membrane as well as inhibiting bacterial attachment altogether. These coatings should extend the indwelling time of catheters significantly. By inhibiting the bacteria, urinary tract infections and catheter encrustation will be significantly reduced compared to the current catheter designs. Surface characterization techniques and antibacterial assays were run to test the efficacy of the coatings.
Of six coatings that were tested, two were able to inhibit biofilm formation significantly better than the current commercially used method of silicone according to a crystal violet assay. One of the coatings, 11-mercapto-trimethylamine (11-MTA) was able to permeabalize very well killing over 90% of all bacteria on the surface. These results showed that amphiphillic cationic molecules are lethal to the membranes of gram-negative bacteria. During this research, a long term, and effective method was developed for preventing urinary tract infections and catheters encrustations for patients who use long term urethral catheters.
Advisors/Committee Members: Joerg Graf, Yu Lei, Mei Wei.
Subjects/Keywords: Polydimethylsiloxane; PDMS; catheter; polydopamine; antibacterial; antifouling; surface modification
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APA (6th Edition):
Russo, J. L. (2014). Inhibition of Urinary Tract Infections and Biofilm Formation on Long-term Indwelling Urethral Catheters through Antibacterial Coatings. (Masters Thesis). University of Connecticut. Retrieved from https://opencommons.uconn.edu/gs_theses/573
Chicago Manual of Style (16th Edition):
Russo, Jonathan L. “Inhibition of Urinary Tract Infections and Biofilm Formation on Long-term Indwelling Urethral Catheters through Antibacterial Coatings.” 2014. Masters Thesis, University of Connecticut. Accessed February 28, 2021.
https://opencommons.uconn.edu/gs_theses/573.
MLA Handbook (7th Edition):
Russo, Jonathan L. “Inhibition of Urinary Tract Infections and Biofilm Formation on Long-term Indwelling Urethral Catheters through Antibacterial Coatings.” 2014. Web. 28 Feb 2021.
Vancouver:
Russo JL. Inhibition of Urinary Tract Infections and Biofilm Formation on Long-term Indwelling Urethral Catheters through Antibacterial Coatings. [Internet] [Masters thesis]. University of Connecticut; 2014. [cited 2021 Feb 28].
Available from: https://opencommons.uconn.edu/gs_theses/573.
Council of Science Editors:
Russo JL. Inhibition of Urinary Tract Infections and Biofilm Formation on Long-term Indwelling Urethral Catheters through Antibacterial Coatings. [Masters Thesis]. University of Connecticut; 2014. Available from: https://opencommons.uconn.edu/gs_theses/573
University of Texas – Austin
17.
Kirschner, Alon Yeshayahu.
Membrane fouling : mechanisms, modeling, and mitigation.
Degree: PhD, Chemical Engineering, 2019, University of Texas – Austin
URL: http://dx.doi.org/10.26153/tsw/5872
► Membrane systems are used for water treatment in many industries due to their small footprint, low chemical and energy use, and ease of operation. However,…
(more)
▼ Membrane systems are used for water treatment in many industries due to their small footprint, low chemical and energy use, and ease of operation. However, membrane fouling remains a challenge, especially for highly concentrated feeds. Fouling increases hydraulic resistance, lowers water permeance and increases energy consumption. Fouled membranes require expensive cleaning or replacement, increasing operating costs. This study focuses on understanding fouling mechanisms in constant flux crossflow operation, commonly used in industry, and on development of novel fouling-resistant membrane coatings.
A model combining two accepted fouling mechanisms, intermediate pore blocking and cake filtration, was developed to describe fouling in constant flux crossflow ultrafiltration (UF). The model was fit to experimental fouling results using rigid and deformable particles. Observations of the model’s accuracy at different fluxes shed light on the physical meaning of the threshold flux: the threshold flux is the flux below which cake buildup is negligible and above which cake filtration becomes the dominant fouling mechanism. Further development of the model may enable fouling prediction.
To mitigate fouling in oil-water separations, two novel membrane coatings were developed. The first coating was based on
polydopamine (PDA), a well-established fouling-resistant coating material. Poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC), a polymer zwitterion, was co-deposited with PDA to form a composite coating on polysulfone (PS) UF membranes. Fouling experiments showed that addition of PMPC to PDA significantly improved fouling resistance. The difference in fouling performance is likely due to the strongly hydrophilic surface properties contributed by PMPC. The co-deposition method opens opportunities for expansion of the concept in which PDA acts as a robust platform for the integration of non-fouling co-adsorbates.
The second coating addresses a weakness of PDA coatings – their sensitivity to aqueous chlorine. Chlorine is widely used as a disinfectant in water purification processes. Chlorine oxidation results in rapid removal of PDA coatings from membrane surfaces, rendering them vulnerable to fouling. Poly(N-methylaniline) (PNMA) is a polyaniline derivative which contains a tertiary amine, rather than a secondary amine as in PDA, making PNMA less vulnerable to chlorine oxidation. PNMA-modified membranes were more stable and had higher fouling resistance than PDA-modified membranes after chlorine exposure.
Advisors/Committee Members: Freeman, B. D. (Benny D.) (advisor), Paul, Donald R. (advisor), Field, Robert W (committee member), Sharma, Mukul M (committee member), Lynd, Nathaniel A (committee member).
Subjects/Keywords: Membrane; Antifouling; Chlorine resistance; Polydopamine; Ultrafiltration; Crossflow; Constant flux
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APA ·
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APA (6th Edition):
Kirschner, A. Y. (2019). Membrane fouling : mechanisms, modeling, and mitigation. (Doctoral Dissertation). University of Texas – Austin. Retrieved from http://dx.doi.org/10.26153/tsw/5872
Chicago Manual of Style (16th Edition):
Kirschner, Alon Yeshayahu. “Membrane fouling : mechanisms, modeling, and mitigation.” 2019. Doctoral Dissertation, University of Texas – Austin. Accessed February 28, 2021.
http://dx.doi.org/10.26153/tsw/5872.
MLA Handbook (7th Edition):
Kirschner, Alon Yeshayahu. “Membrane fouling : mechanisms, modeling, and mitigation.” 2019. Web. 28 Feb 2021.
Vancouver:
Kirschner AY. Membrane fouling : mechanisms, modeling, and mitigation. [Internet] [Doctoral dissertation]. University of Texas – Austin; 2019. [cited 2021 Feb 28].
Available from: http://dx.doi.org/10.26153/tsw/5872.
Council of Science Editors:
Kirschner AY. Membrane fouling : mechanisms, modeling, and mitigation. [Doctoral Dissertation]. University of Texas – Austin; 2019. Available from: http://dx.doi.org/10.26153/tsw/5872
King Abdullah University of Science and Technology
18.
Julfakyan, Khachatur.
Hybrid Theranostic Platforms for Cancer Nanomedical Treatment.
Degree: Physical Science and Engineering (PSE) Division, 2015, King Abdullah University of Science and Technology
URL: http://hdl.handle.net/10754/582476
► Cancer is a leading case of mortality worldwide. Governments spent multibillion expenses on treatment and palliative care of diseased people. Despite these generous funding and…
(more)
▼ Cancer is a leading case of mortality worldwide. Governments spent multibillion expenses on treatment and palliative care of diseased people. Despite these generous funding and intensive research with aim to find a cure or efficient treatment for cancer, until now there is a lack in selective cancer management strategies. Conventional treatment strategies for cancer, such as surgery, cytotoxic chemotherapy, radiation therapy, hormone therapy don’t have selectivity toward cancer – the property of discrimination of healthy organs and tissues from the diseased site. Chemotherapy is very challenging as the difference between effective and lethal doses is very minuscule in most cases. Moreover, devastating side effects dramatically changes the quality of life for cancer patients. To address these issues two main strategies are intensively utilized in chemistry: (I) the design and synthesis of novel anticancer organic compounds with higher selectivity and low toxicity profiles and the second, design and preparation of biocompatible nanocarriers for imaging and anticancer compound selective delivery nanomedicine. The following dissertation combines the above two strategies as bellows: First project is related to the design and synthetic route development toward novel nature-inspired group of heterocyclic compounds – iso-Phidianidines. The second project focused on design, preparation and evaluation of hybrid theranostics (therapeutic and diagnostic in a single entity).
Chapter 1 is a general background review of the major topics that will be discussed in this dissertation.
The first efficient and high-yielding synthetic route toward iso-phidianidines, containing regioisomeric form of 1,2,4-oxadiazole linked to the indole via methylene bridge is reported in Chapter 2. In vitro test of the synthesized library of iso-phidianidines revealed micromolar range of cytotoxicity toward human cervical cancer cell line. Structure activity relationship revealed the importance of presence of monosubsituted amine in 3 position of oxadiazole to maintain activity. Moreover, gradual increase of activity was detected in increasing of the length of the diamine. Polyamine (spermidine) side chain demonstrated strongest anticancer activity, identified as lead compound and may be studied further as a good candidate for cervical cancer treatment. Finally, the remaining high activity of amino-terminated iso-phidianidines demonstrated that presence of guanidine group in termini is not necessary for high cytotoxicity.
The second part of this dissertation (Chapter 3) discusses the rational design, wet protocol synthesis and complete characterization of the novel hybrid material –
polydopamine coated iron-cobalt nanocubes (PDFCs). This material was loaded with anticancer model drug doxorubicin in one step procedure (PDFC-DOX) and the resulting drug-delivery vehicle was found to be successfully internalized by cervical cancer cells. The cytotoxicity test demonstrated inhibition of 50% of the cells at the concentration of 30μg/ml for PDFC-DOX.…
Advisors/Committee Members: Khashab, Niveen M. (advisor), Hadjichristidis, Nikos (committee member), Cavallo, Luigi (committee member), Amassian, Aram (committee member), Al Faraj, Achraf (committee member).
Subjects/Keywords: iron-cobalt nanoparticles; polydopamine; Nanomedicine; Theranostics; cancer; one-for-all
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APA (6th Edition):
Julfakyan, K. (2015). Hybrid Theranostic Platforms for Cancer Nanomedical Treatment. (Thesis). King Abdullah University of Science and Technology. Retrieved from http://hdl.handle.net/10754/582476
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Julfakyan, Khachatur. “Hybrid Theranostic Platforms for Cancer Nanomedical Treatment.” 2015. Thesis, King Abdullah University of Science and Technology. Accessed February 28, 2021.
http://hdl.handle.net/10754/582476.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Julfakyan, Khachatur. “Hybrid Theranostic Platforms for Cancer Nanomedical Treatment.” 2015. Web. 28 Feb 2021.
Vancouver:
Julfakyan K. Hybrid Theranostic Platforms for Cancer Nanomedical Treatment. [Internet] [Thesis]. King Abdullah University of Science and Technology; 2015. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/10754/582476.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Julfakyan K. Hybrid Theranostic Platforms for Cancer Nanomedical Treatment. [Thesis]. King Abdullah University of Science and Technology; 2015. Available from: http://hdl.handle.net/10754/582476
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
19.
Masse, Morgane.
Etudes des interactions contenu-contenant avec le polychlorure de vinyle et développement de méthodes de prévention de ces interactions : Studies of content-container interactions with polyvinyl chloride and development of methods to prevent these interactions.
Degree: Docteur es, Pharmacie sciences du médicament et autres produits de santé, 2018, Université Lille II – Droit et Santé
URL: http://www.theses.fr/2018LIL2S044
► Le polychlorure de vinyle (PVC) est un matériau très utilisé dans la fabrication desdispositifs médicaux (DMs) tels que les prolongateurs et les tubulures de perfusion.Cependant,…
(more)
▼ Le polychlorure de vinyle (PVC) est un matériau très utilisé dans la fabrication desdispositifs médicaux (DMs) tels que les prolongateurs et les tubulures de perfusion.Cependant, le PVC est sujet à 2 types d'interactions contenu-contenant. La première est lasorption pouvant conduire à un sous-dosage médicamenteux puisque la dose de principe actifne sera pas totalement administrée, ou conduire à une modification de la formulationgalénique du médicament (en cas de sorption des excipients). La deuxième interaction est lamigration des plastifiants. Les fabricants ajoutent au PVC des plastifiants pour l'assouplir, ilspeuvent être présents jusqu'à 40-50% masse/masse. Certains des plastifiants sontactuellement considérés comme des molécules carcinogènes, mutagènes et reprotoxiques declasse lb. Toutefois, ces plastifiants n'étant pas liés de façon covalente avec le PVC, ceux-cipeuvent migrer et entrer en contact avec le patient.Les objectifs de cette thèse sont :1. De mettre en évidence les phénomènes de sorption avec le PVC au travers de deuxsolutions commerciales d'insuline : l'Umuline rapide® (insuline humaine) et la Novorapid®(insuline asparte).2. D'optimiser une méthode de dosage permettant la caractérisation des sept plastifiantsutilisés dans la fabrication des DMs en PVC grâce à l'utilisation de la dérivée première desspectres UV et d'appliquer cette méthode à des DMs commercialisés.3. De mettre au point un procédé de modification (fonctionnalisation) de la surface duPVC pour limiter ces interactions contenu-contenant. L'idée est de créer une barrière àl'extrême surface (de quelques nanomètres) sans modifier les propriétés en profondeur duPVC et de limiter la sorption des principes actifs (le diazépam, DZP) et la migration desplastifiants. Deux plastifiants sont étudiés, le 1,2-cyclohexane dicarboxylic acid diisononylester (DINCH) et le tri-octyltrimellitate (TOTM) qui sont les plastifiants les plus retrouvés dansces DMs en PVC.Les deux insulines (asparte - Novorapid® et humaine - Umuline rapide®) présentent uneinteraction, lors de la première heure de perfusion, avec le PVC. Après 30 minutes deperfusion, le pourcentage d'insuline humaine recueillie est de 75,7 ± 12,9% et celui d'insulineasparte de 91,2 ± 4,6%. En revanche, les conservateurs qui permettent le maintien del'insuline sous sa conformation la plus stable (forme hexamérique) sont beaucoup plus sujetsà la sorption avec le PVC. Pour l'insuline Novorapid® le pourcentage de perte de métacrésolest de 50,3 ± 12,1% et celui du phénol est de 39,7 ± 19,6% après trente minutes de perfusion.Concernant l'insuline Umuline rapide®, le pourcentage de perte du métacrésol est de 77,5 ±12,5%.La méthode de dosage des plastifiants permet la qualification et la quantification des septplastifiants utilisés dans la fabrication des DMs en PVC. La quantification des plastifiants estcomprise entre 0,3 à 750 pg/mL selon le plastifiant. Les gammes d'étalonnage des plastifiantssont validées par une analyse de la variance. Cette méthode est ensuite utilisée pour le dosagedes…
Advisors/Committee Members: Barthélémy, Christine (thesis director), Blanchemain, Nicolas (thesis director).
Subjects/Keywords: Polychlorure de vinyle; Plastifiants; Interactions contenu-contenant; Fonctionnalisation; Plasma froid basse pression; Polydopamine; Polyvinyl chloride; Plasticizers; Content-container interactions; Functionalization; Low pressure cold plasma; Polydopamine
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APA ·
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APA (6th Edition):
Masse, M. (2018). Etudes des interactions contenu-contenant avec le polychlorure de vinyle et développement de méthodes de prévention de ces interactions : Studies of content-container interactions with polyvinyl chloride and development of methods to prevent these interactions. (Doctoral Dissertation). Université Lille II – Droit et Santé. Retrieved from http://www.theses.fr/2018LIL2S044
Chicago Manual of Style (16th Edition):
Masse, Morgane. “Etudes des interactions contenu-contenant avec le polychlorure de vinyle et développement de méthodes de prévention de ces interactions : Studies of content-container interactions with polyvinyl chloride and development of methods to prevent these interactions.” 2018. Doctoral Dissertation, Université Lille II – Droit et Santé. Accessed February 28, 2021.
http://www.theses.fr/2018LIL2S044.
MLA Handbook (7th Edition):
Masse, Morgane. “Etudes des interactions contenu-contenant avec le polychlorure de vinyle et développement de méthodes de prévention de ces interactions : Studies of content-container interactions with polyvinyl chloride and development of methods to prevent these interactions.” 2018. Web. 28 Feb 2021.
Vancouver:
Masse M. Etudes des interactions contenu-contenant avec le polychlorure de vinyle et développement de méthodes de prévention de ces interactions : Studies of content-container interactions with polyvinyl chloride and development of methods to prevent these interactions. [Internet] [Doctoral dissertation]. Université Lille II – Droit et Santé 2018. [cited 2021 Feb 28].
Available from: http://www.theses.fr/2018LIL2S044.
Council of Science Editors:
Masse M. Etudes des interactions contenu-contenant avec le polychlorure de vinyle et développement de méthodes de prévention de ces interactions : Studies of content-container interactions with polyvinyl chloride and development of methods to prevent these interactions. [Doctoral Dissertation]. Université Lille II – Droit et Santé 2018. Available from: http://www.theses.fr/2018LIL2S044
20.
Lutzweiler, Gaëtan.
Porous polyurethane-based materials for tissue engineering : Matériaux poreux à base de polyuréthane pour l’ingénierie tissulaire.
Degree: Docteur es, Biophysique, 2019, Université de Strasbourg
URL: http://www.theses.fr/2019STRAE019
► Les matériaux poreux représentent une solution idéale en ingénierie tissulaire car leur structure peut offrir un environnement tridimensionnel aux cellules similaire à leur matrice extracellulaire…
(more)
▼ Les matériaux poreux représentent une solution idéale en ingénierie tissulaire car leur structure peut offrir un environnement tridimensionnel aux cellules similaire à leur matrice extracellulaire tout en maintenant de bonnes propriétés mécaniques. Une première partie de cette thèse consiste à développer des matériaux poreux en polyuréthane (PU), dont l’architecture est contrôlée pour favoriser au mieux la survie et la croissance des cellules. Ces matériaux sont combinés à des traitements de surface (revêtement de polydopamine (PDA) et traitement plasma) pour augmenter notamment l’adhésion des cellules. Nous avons pu démontrer que le diamètre des interconnexions (i.e. l’ouverture connectant deux pores adjacents) impacte profondément la survie et l’organisation des cellules à long terme dans le matériau. Le revêtement de PDA s’est révélé efficace pour des cellules de type fibroblaste, alors que le traitement plasma favorise la colonisation des cellules souches mésenchymateuses (MSCs). Par ailleurs, nous avons étudié l’influence de la formulation du PU sur les capacités d’adhésion des cellules au matériau. Nous avons démontré que pour un ratio donné entre les réactifs, l’adhésion des cellules peut être exclue ou permise. Finalement, nous avons mis un gel de peptides auto-assemblés dans les pores du matériau pour fournir aux cellules un environnement similaire à leur matrice extracellulaire. Nous avons pu montrer que le gel permet d’augmenter la prolifération des MSCs.
Porous materials are an ideal solution in tissue engineering since they can provide a three-dimensional environment to the cells that is close to their extracellular matrix while keeping suitable mechanical properties. In the first part of this Thesis we develop porous materials made from polyurethane (PU) whose architecture is controlled to allow cells colonisation and growth. These materials are subsequently surface-treated (polydopamine (PDA) coating and plasma treatment) to enhance the adhesion of the cells. We were able to show that the interconnection diameter (i.e. the aperture connecting two adjacent pores) has an important impact on the long-term cell survival and organization in the material. Polydopamine coating was shown to be efficient for fibroblasts, whereas plasma treatment promoted mesenchymal stem cells (MSCs) colonisation. Besides, we also studied the influence of the PU formulation on the adhesion capacity of the cells. We demonstrated that at a given ratio between the reactants, cell adhesion could be allowed or prevented. Finally, we put a hydrogel of self-assembled peptides inside the pores of the material to provide an environment close to the extracellular matrix for the cells. We could show that the gel increases the proliferation ability of MSCs. In summary, this Thesis puts forward the important interplay between material properties and morphology of porous scaffolds.
Advisors/Committee Members: Schaaf, Pierre (thesis director), Drenckhan-Andreatta, Wiebke (thesis director).
Subjects/Keywords: Matériaux poreux; Diamètre d’interconnexion; Revêtement de surface; Polyuréthane; Cellules souches mésenchymateuses; Polydopamine; Porous materials; Interconnection diameter; Surface functionalisation; Polyurethane; Mesenchymal stem cells; Polydopamine; 620.116; 668 423 9; 571.43
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APA (6th Edition):
Lutzweiler, G. (2019). Porous polyurethane-based materials for tissue engineering : Matériaux poreux à base de polyuréthane pour l’ingénierie tissulaire. (Doctoral Dissertation). Université de Strasbourg. Retrieved from http://www.theses.fr/2019STRAE019
Chicago Manual of Style (16th Edition):
Lutzweiler, Gaëtan. “Porous polyurethane-based materials for tissue engineering : Matériaux poreux à base de polyuréthane pour l’ingénierie tissulaire.” 2019. Doctoral Dissertation, Université de Strasbourg. Accessed February 28, 2021.
http://www.theses.fr/2019STRAE019.
MLA Handbook (7th Edition):
Lutzweiler, Gaëtan. “Porous polyurethane-based materials for tissue engineering : Matériaux poreux à base de polyuréthane pour l’ingénierie tissulaire.” 2019. Web. 28 Feb 2021.
Vancouver:
Lutzweiler G. Porous polyurethane-based materials for tissue engineering : Matériaux poreux à base de polyuréthane pour l’ingénierie tissulaire. [Internet] [Doctoral dissertation]. Université de Strasbourg; 2019. [cited 2021 Feb 28].
Available from: http://www.theses.fr/2019STRAE019.
Council of Science Editors:
Lutzweiler G. Porous polyurethane-based materials for tissue engineering : Matériaux poreux à base de polyuréthane pour l’ingénierie tissulaire. [Doctoral Dissertation]. Université de Strasbourg; 2019. Available from: http://www.theses.fr/2019STRAE019
NSYSU
21.
Lin, Jia-hui.
Development of molecular- and nanomaterial-based probes for sensing biomolecules and metal ions.
Degree: PhD, Chemistry, 2015, NSYSU
URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0104115-131206
► The purpose of this thesis is to describe how to develop molecular- and nanomaterial-based biosensor for sensing biomolecules and metal ions. The thesis consists of…
(more)
▼ The purpose of this thesis is to describe how to develop molecular- and nanomaterial-based biosensor for sensing biomolecules and metal ions. The thesis consists of four independent works. (1) A simple and label-free fluorescent method for sensitive and selective detection of adenosine in urine sample was developed based on adenosine-induced inhibition of adenosylhomocysteine hydrolase (SAHH) activity. Without the addition of nucleophile, 2,3-naphthalenedicarboxaldehyde (NDA) was found to selectively react with homocysteine to form fluorescent product. Adenosine is efficient to inhibit the production of homocysteine from the hydrolysis reaction between SAHH and adenosylhomocysteine. Taken together, the fluorescence of NDA-homocysteine derivatives decreased with an increase in the adenosine concentration. As a result, the SAHH-based probe provided high sensitivity (a limit of detection for adenosine of 0.3 μM) and high selectivity (more than 100-fold for andenosine over any adenosine analogs). (2) A set of two-input and three-input DNA logic gates was constructed using non-Waston-Crick base pairing-based molecular beacon (MB). The presence of Hg2+, Ag+, and coralyne promoted the conformational changes of MB via the formation of T-Hg2+-T, C-Ag+-C, and A2-coralyne-A2 coordination, resulting in its fluorescent quenching. It was found that thiols, complexing agents, and polyadenosine can remove Hg2+, Ag+, and coralyne from the hairpin-shaped MB, respectively. Based on these phenomenon, the designed MB generated a series of two-input, three-input, and set-reset logic operation at the molecular level. (3) Laser-induced light scattering technique with the adevantages of high sensitivity, low cost, portability, and miniaturization was applied for sensing three gold nanoparticle-based sensing systems, including salt-, thiol-, and metal ion-induced nanoparticle aggregation. The combination of a miniatuarized spectrometer with a 532-nm laser allows the sensitive detection of Rayleigh scattering from nanoparticles aggregation. As a result, the proposed system provided more than 10-fold sensitivity improvement as compared to colorimetric assay. (4) Fluorescent
polydopamine particles was prepared through hydroxyl-radical degradation of
polydopamine nanoparticles. The production of fluorescent
polydopamine was demonstrated using transmission electron microscope, dark field microscope, and thermogravimetric analyzer. The possible chemical compositions of
polydopamine dots were determined using Fourier transform infrared spectrosmeter and laser desorption/ionization-time-of-flight mass spectrometer. Additionally, fluorescent
polydopamine dots were used for sensitive and selective detection of Fe(III) through coordination between the catechol group of fluorescent
polydopamine dots and Fe(III). This sensing mechanism relied on electron-transfer-induced fluorescence quenching.
Advisors/Committee Members: Po-Chiao Lin (chair), Yang-Hsiang Chan (chair), Shou-Mei Wu (chair), Shiuh-jen Jiang (chair), Wei-Lung Tseng (committee member).
Subjects/Keywords: inhibition; derivatization; molecular logic gates; molecular beacon; gold nanoparticles; light scattering; fluorescent polydopamine
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APA (6th Edition):
Lin, J. (2015). Development of molecular- and nanomaterial-based probes for sensing biomolecules and metal ions. (Doctoral Dissertation). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0104115-131206
Chicago Manual of Style (16th Edition):
Lin, Jia-hui. “Development of molecular- and nanomaterial-based probes for sensing biomolecules and metal ions.” 2015. Doctoral Dissertation, NSYSU. Accessed February 28, 2021.
http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0104115-131206.
MLA Handbook (7th Edition):
Lin, Jia-hui. “Development of molecular- and nanomaterial-based probes for sensing biomolecules and metal ions.” 2015. Web. 28 Feb 2021.
Vancouver:
Lin J. Development of molecular- and nanomaterial-based probes for sensing biomolecules and metal ions. [Internet] [Doctoral dissertation]. NSYSU; 2015. [cited 2021 Feb 28].
Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0104115-131206.
Council of Science Editors:
Lin J. Development of molecular- and nanomaterial-based probes for sensing biomolecules and metal ions. [Doctoral Dissertation]. NSYSU; 2015. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0104115-131206
22.
LYU QINGHUA.
TOWARDS THE DEVELOPMENT OF BIOMIMETIC MATERIALS FOR POTENTIAL BIOMEDICAL APPLICATIONS: AN INVESTIGATION ON CATECHOLAMINES-BASED COATINGS FOR SURFACE FUNCTIONALIZATION.
Degree: 2018, National University of Singapore
URL: https://scholarbank.nus.edu.sg/handle/10635/155544
Subjects/Keywords: surface coatings; biomimetic; catechol; catecholamine; polydopamine
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APA (6th Edition):
QINGHUA, L. (2018). TOWARDS THE DEVELOPMENT OF BIOMIMETIC MATERIALS FOR POTENTIAL BIOMEDICAL APPLICATIONS: AN INVESTIGATION ON CATECHOLAMINES-BASED COATINGS FOR SURFACE FUNCTIONALIZATION. (Thesis). National University of Singapore. Retrieved from https://scholarbank.nus.edu.sg/handle/10635/155544
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
QINGHUA, LYU. “TOWARDS THE DEVELOPMENT OF BIOMIMETIC MATERIALS FOR POTENTIAL BIOMEDICAL APPLICATIONS: AN INVESTIGATION ON CATECHOLAMINES-BASED COATINGS FOR SURFACE FUNCTIONALIZATION.” 2018. Thesis, National University of Singapore. Accessed February 28, 2021.
https://scholarbank.nus.edu.sg/handle/10635/155544.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
QINGHUA, LYU. “TOWARDS THE DEVELOPMENT OF BIOMIMETIC MATERIALS FOR POTENTIAL BIOMEDICAL APPLICATIONS: AN INVESTIGATION ON CATECHOLAMINES-BASED COATINGS FOR SURFACE FUNCTIONALIZATION.” 2018. Web. 28 Feb 2021.
Vancouver:
QINGHUA L. TOWARDS THE DEVELOPMENT OF BIOMIMETIC MATERIALS FOR POTENTIAL BIOMEDICAL APPLICATIONS: AN INVESTIGATION ON CATECHOLAMINES-BASED COATINGS FOR SURFACE FUNCTIONALIZATION. [Internet] [Thesis]. National University of Singapore; 2018. [cited 2021 Feb 28].
Available from: https://scholarbank.nus.edu.sg/handle/10635/155544.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
QINGHUA L. TOWARDS THE DEVELOPMENT OF BIOMIMETIC MATERIALS FOR POTENTIAL BIOMEDICAL APPLICATIONS: AN INVESTIGATION ON CATECHOLAMINES-BASED COATINGS FOR SURFACE FUNCTIONALIZATION. [Thesis]. National University of Singapore; 2018. Available from: https://scholarbank.nus.edu.sg/handle/10635/155544
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Loughborough University
23.
Zhu, Bocheng.
Surface initiated polymerisation for applications in materials science.
Degree: PhD, 2012, Loughborough University
URL: http://hdl.handle.net/2134/10858
► A systematic study of the surface-initiated polymerisation kinetics of a relatively new type of atom transfer radical polymerisation (ATRP), activators regenerated by electron transfer (ARGET)…
(more)
▼ A systematic study of the surface-initiated polymerisation kinetics of a relatively new type of atom transfer radical polymerisation (ATRP), activators regenerated by electron transfer (ARGET) ATRP, is first demonstrated in this report. Poly(2-hydroxyethyl methacrylate) (PHEMA) and poly(methyl methacrylate) (PMMA) were successfully grown from silicon surfaces at room temperature by surface-initiated ARGET ATRP using a "3rd generation" cationic macroinitiator. The polymer films were analysed by ellipsometry, X-ray photoelectron spectroscopy (XPS) and Fourier transform infrared spectroscopy (FTIR). With the initial experiment showing that water accelerated conventional ATRP but made it less controlled, the effect of solvent on ARGET ATRP was also evaluated. The living character of ARGET ATRP was demonstrated by successfully reinitiating PHEMA-grafted silicon wafers to grow a second block of PHEMA. Initiator density was shown to have a great effect on the growth rate of PHEMA film thickness on silicon surfaces by comparing the ARGET ATRP growth of PHEMA films using two different initiators, "1st generation" and "3rd generation" cationic macroinitiators, which have different ratios of initiating groups to positive charge. Another type of initiator for ATRP systems, an amide silane, was then investigated as an alternative to polyelectrolyte macroinitiators to avoid degrafting. The effects of solvent, 2, 2′ bipyridyl (bpy) ligand concentration and different types of reducing agent on the growth of PHEMA film from amide-initiator coated silicon wafers by ARGET ATRP were then explored at room temperature. However, it was found that the swings in the uncontrolled laboratory ambient temperature caused inter-sample and inter-experiment variability and so could make the evaluations inaccurate or even wrong. An investigation of temperature on ARGET ATRP showed a dramatic effect on the polymerisation rate. The higher the temperature, the faster the polymerisation proceeded. Therefore, the effects of solvent, ratio of bpy to Cu and reducing agent on the ARGET ATRP growth of PHEMA brushes from amide initiator-coated silicon wafers were re-evaluated at a constant temperature, 30 °C. The development of a polydopamine-based initiator, which was designed to be able to be immobilised on a wide range of surfaces, is then presented in this report. Polydopamine was first shown to be able to deposit on various types of material surfaces by oxidative polymerisation in aqueous solution. Bromoester initiating groups for ATRP systems were incorporated into polydopamine coatings by reacting a fraction of the dopamine monomer with 2-bromoisobutyryl bromide (BIBB) before polymerisation. The modified polydopamine initiator film grew at a comparable rate to unmodified polydopamine, with a 45 nm being grown in 24 hours. Successful incorporation of initiator groups was confirmed by XPS and FTIR, and by the growth of PMMA and PHEMA polymer brushes by ARGET ATRP from the polydopamine initiator coatings. A PMMA brush with a thickness of 239 nm was grown…
Subjects/Keywords: 620.11; Surface-initiated polymerisation; Polymer brushes; Polydopamine; Surface-independent initiator; Interfacial adhesion
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APA ·
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APA (6th Edition):
Zhu, B. (2012). Surface initiated polymerisation for applications in materials science. (Doctoral Dissertation). Loughborough University. Retrieved from http://hdl.handle.net/2134/10858
Chicago Manual of Style (16th Edition):
Zhu, Bocheng. “Surface initiated polymerisation for applications in materials science.” 2012. Doctoral Dissertation, Loughborough University. Accessed February 28, 2021.
http://hdl.handle.net/2134/10858.
MLA Handbook (7th Edition):
Zhu, Bocheng. “Surface initiated polymerisation for applications in materials science.” 2012. Web. 28 Feb 2021.
Vancouver:
Zhu B. Surface initiated polymerisation for applications in materials science. [Internet] [Doctoral dissertation]. Loughborough University; 2012. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/2134/10858.
Council of Science Editors:
Zhu B. Surface initiated polymerisation for applications in materials science. [Doctoral Dissertation]. Loughborough University; 2012. Available from: http://hdl.handle.net/2134/10858
24.
-0558-4880.
Surface modification of water purification membranes to improve fouling resistance in oily water filtration.
Degree: PhD, Chemical engineering, 2015, University of Texas – Austin
URL: http://hdl.handle.net/2152/32918
► One of the biggest challenges in using water purification membranes is fouling. Surface modification using hydrophilic materials can reduce hydrophobic interactions between membrane surface and…
(more)
▼ One of the biggest challenges in using water purification membranes is fouling. Surface modification using hydrophilic materials can reduce hydrophobic interactions between membrane surface and hydrophobic foulants, thereby alleviating fouling. In this Ph.D. research,
polydopamine (PDA), a highly hydrophilic and universal coating agent, was used to surface-modified reverse osmosis (RO) and ultrafiltration (UF) membranes. PDA modification conditions (e.g., dopamine coating solution concentration, coating time, and pH of coating solution) control PDA deposition and can directly influence the modified membrane properties. Thus, the influence of PDA modification conditions on membrane physical, permeation, selective, and fouling properties were investigated systematically. A fundamental understanding relating the physical and permeation properties and the fouling characteristics of PDA-modified membranes was established.
The RO membranes were modified with PDA at various modification conditions. Permeate fluxes during pure water and oil/water emulsion filtrations were studied. The PDA modification increased the permeate fluxes during oil/water emulsion filtration (thus, improved membrane fouling resistance) relative to unmodified membranes regardless of the initial dopamine concentration or deposition time used. However, these changes were only observed for the membranes coated under alkaline conditions, suggesting that the PDA did not deposit well under acidic condition.
For UF membranes, molecular weight cutoff (MWCO) and pure water permeance decreased with increasing initial dopamine concentration or deposition time. A permeability and selectivity tradeoff was also observed. Membrane mean pore size and pore size distribution (modeled using log-normal pore size distribution) were investigated via modelling using a hindered solute transport model, Hagen-Poiseuille equation, and a stagnant film model.
The PDA modification increased UF membrane surface hydrophilicity regardless of the coating conditions used, but it did not clearly change surface roughness or zeta potential (i.e., surface charge). Membrane fouling propensity was characterized using threshold flux. Compared to unmodified membranes, the threshold flux increased at minimal PDA coatings, but decreased at excessive PDA coatings. These threshold flux changes were likely governed by a tradeoff between surface hydrophilicity increase and pure water permeance decrease. Excessive PDA coatings resulted in decreased pure water permeance and possibly, pore blockage and pore size reduction, leading to higher local permeate flux causing severe fouling and decreased threshold flux.
Advisors/Committee Members: Freeman, B. D. (Benny D.) (advisor), Sharma, Mukul M. (advisor), Paul, Donald R (committee member), Sanchez, Isaac C (committee member), Ellison, Christopher J (committee member), Emrick, Todd S (committee member).
Subjects/Keywords: Polydopamine; Fouling; Surface modification; Membranes
…and hydrophobic foulants, thereby alleviating fouling. In this
Ph.D. research, polydopamine… …2
1.4 Membrane Fouling and Polydopamine as a Fouling-Resistant Coating
Material… …12
2.1 Polydopamine for Membrane Surface Modification ..............................12… …2.1.1 Polydopamine Modification to Improve Membrane Fouling
Resistance… …12
2.1.2 Influence of Polydopamine Deposition Conditions on Membrane
Properties…
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APA ·
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APA (6th Edition):
-0558-4880. (2015). Surface modification of water purification membranes to improve fouling resistance in oily water filtration. (Doctoral Dissertation). University of Texas – Austin. Retrieved from http://hdl.handle.net/2152/32918
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Chicago Manual of Style (16th Edition):
-0558-4880. “Surface modification of water purification membranes to improve fouling resistance in oily water filtration.” 2015. Doctoral Dissertation, University of Texas – Austin. Accessed February 28, 2021.
http://hdl.handle.net/2152/32918.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
MLA Handbook (7th Edition):
-0558-4880. “Surface modification of water purification membranes to improve fouling resistance in oily water filtration.” 2015. Web. 28 Feb 2021.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Vancouver:
-0558-4880. Surface modification of water purification membranes to improve fouling resistance in oily water filtration. [Internet] [Doctoral dissertation]. University of Texas – Austin; 2015. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/2152/32918.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Council of Science Editors:
-0558-4880. Surface modification of water purification membranes to improve fouling resistance in oily water filtration. [Doctoral Dissertation]. University of Texas – Austin; 2015. Available from: http://hdl.handle.net/2152/32918
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
University of Manchester
25.
Zeng, Lei.
Fibre Surface Modification with Polydopamine and Graphene
Oxide for Improvement of Interface in Composites.
Degree: 2020, University of Manchester
URL: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:326445
► Carbon and aramid fibre-reinforced composites have been applied in various areas. However, both carbon and aramid fibres have chemically inert surfaces, and the manufactured fibre…
(more)
▼ Carbon and aramid fibre-reinforced composites have
been applied in various areas. However, both carbon and aramid
fibres have chemically inert surfaces, and the manufactured fibre
reinforced composites do not always achieve expectations derived
from the properties of its constituents. This research aims to
improve the bonding between these fibres and epoxy resin system.
Inspired by the composition of adhesive proteins in mussels,
dopamine was self-polymerised onto the fibre surfaces via pi-pi
stacking to form a nano-thin, surface-adherent
polydopamine (PDA)
layer. Graphene oxide (GO) was then grafted on fibres through the
PDA layer to achieve interface improvement in composites. The fibre
surface treatment and modification were performed at ambient
temperature and it is non-destructive to the fibres. The scanning
electron microscope (SEM) and atomic force microscope (AFM) results
indicated that surface roughness was significantly increased after
the surface modification. Microbond tests showed that the
interfacial shear strength between modified fibre and epoxy resin
was improved up to 69.3% and 151.5% for carbon fibre and aramid
fibre, respectively. The tensile strength of modified carbon fibre
was increased up to 82.1%, while for aramid fibre, the tensile
strength was improved up to 24.0%. The X-ray photoelectron
spectroscopy (XPS) results demonstrated that the pi-pi interaction
of the PDA- and GO-PDA treated fibre was increased. The strong
pi-pi bonding results in enhanced interfacial shear strength
between fibre and matrix. The fibre-reinforced composites were
developed with modified carbon and aramid fibres. The interlaminar
shear strength of composites was increased by 18.8% and 6.3% for
GO-PDA modified carbon fibre and aramid fibre composites,
respectively. The research indicated that pi-pi interaction based
fibre modification has the potential to be extended for surface
modification of other chemically inert high-performance fibres.
Moreover, this non-destructive approach can improve the composites
performance and also extend the applications of fibre-reinforced
composites.
Advisors/Committee Members: SOUTIS, CONSTANTINOS C, LIU, XUQING X, Chen, Xiaogang, Soutis, Constantinos, Liu, Xuqing.
Subjects/Keywords: Fibre Surface Modification; pi-pi interaction; Interface Improvement; Polydopamine; Graphene Oxide; Fibre reinforced composites
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APA ·
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APA (6th Edition):
Zeng, L. (2020). Fibre Surface Modification with Polydopamine and Graphene
Oxide for Improvement of Interface in Composites. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:326445
Chicago Manual of Style (16th Edition):
Zeng, Lei. “Fibre Surface Modification with Polydopamine and Graphene
Oxide for Improvement of Interface in Composites.” 2020. Doctoral Dissertation, University of Manchester. Accessed February 28, 2021.
http://www.manchester.ac.uk/escholar/uk-ac-man-scw:326445.
MLA Handbook (7th Edition):
Zeng, Lei. “Fibre Surface Modification with Polydopamine and Graphene
Oxide for Improvement of Interface in Composites.” 2020. Web. 28 Feb 2021.
Vancouver:
Zeng L. Fibre Surface Modification with Polydopamine and Graphene
Oxide for Improvement of Interface in Composites. [Internet] [Doctoral dissertation]. University of Manchester; 2020. [cited 2021 Feb 28].
Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:326445.
Council of Science Editors:
Zeng L. Fibre Surface Modification with Polydopamine and Graphene
Oxide for Improvement of Interface in Composites. [Doctoral Dissertation]. University of Manchester; 2020. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:326445
Université du Québec à Montréal
26.
Nirasay, Souryvanh.
Élaboration de membranes phospholipidiques supportées sur des surfaces nanopatternées en vue d'améliorer le criblage des médicaments.
Degree: 2017, Université du Québec à Montréal
URL: http://archipel.uqam.ca/10485/1/D3279.pdf
► Les bicouches lipidiques supportées sur surface solide (s-SLBs) sont largement utilisées pour mimer les membranes biologiques. Elles consistent en une bicouche lipidique continue déposée directement…
(more)
▼ Les bicouches lipidiques supportées sur surface solide (s-SLBs) sont largement utilisées pour mimer les membranes biologiques. Elles consistent en une bicouche lipidique continue déposée directement sur un support solide. Cependant, l'existence d'interactions lipide-solide entraîne une perte de la mobilité des lipides et une diminution de la fluidité naturelle des membranes. Un modèle satisfaisant devrait inclure un recouvrement de surface par la bicouche sur de larges régions ainsi que le maintien de la mobilité latérale des lipides, d'une importance déterminante pour garantir un modèle pertinent des biomembranes. La première partie de cette recherche visait à résoudre ce problème en élaborant un modèle de bicouche lipidique supportée par un coussin polymère (p-SLB), dans lequel le polymère agirait en tant que couche lubrifiante entre la membrane et le support solide. Le polymère bioinspiré polydopamine (PDA) a été choisi en raison de son aptitude à former facilement des revêtements minces sur une grande variété de surfaces, avec un contrôle de l'épaisseur en fonction du temps d'immersion du substrat. La caractérisation du polymère a été réalisée par des mesures d'angle de contact, spectroscopie photoélectronique par rayons X (XPS), ellipsométrie et microscopie à force atomique (AFM). Une surface de mica modifié avec la PDA a été utilisée pour supporter des bicouches de phospholipides zwitterioniques de dimyristoylphosphatidylcholine (DMPC) ou dioléoylphosphatidylcholine (DOPC) ; la phosphatidylcholine étant le phospholipide le plus abondant dans les membranes des cellules eucaryotes. Cependant, la caractérisation par AFM a révélé la formation de patches lipidiques sur la PDA au lieu d'une bicouche continue. Sur la base de considérations électrostatiques, nous avons incorporé un lipide cationique, le 3ß-[N-(N',N'-diméthylaminoéthane) carbamoyl]cholestérol (DC-Chol) dans la composition liposomale afin d'attirer davantage de vésicules à la surface de PDA chargée négativement et ainsi favoriser les interactions vésicules-polymère au cours du processus de fusion de vésicules. Nous avons de nouveau utilisé l'imagerie d'AFM ainsi que des techniques de caractérisation de surface telles que la résonance des plasmons de surface (SPR) et la Microbalance à cristal de quartz avec Dissipation (QCM-D) pour examiner davantage la formation des membranes à la surface du polymère. La microscopie de fluorescence via des expériences de FRAP a été utilisée pour évaluer la mobilité des phospholipides. Les résultats ont prouvé que notre stratégie permettait l'obtention d'une bicouche continue avec plus de 90 % de la surface polymère recouverte par une membrane de DOPC/DC-Chol (70/30). Le film de PDA s'est également avéré efficace pour maintenir la fluidité des bicouches phospholipidiques, améliorant ainsi cette classe de membrane modèle. Le second objectif de cette recherche fut de développer un modèle amélioré du test Parallel Artificial Membrane Permeability Assay (PAMPA). Les tests PAMPA sont largement utilisés dans l'industrie…
Subjects/Keywords: Membranes lipidiques bimoléculaires; Phospholipides; Polydopamine; Polymères biomimétiques; Nanomatériaux; Parallel Artificial Membrane Permeability Assay (PAMPA); Criblage à haut débit
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APA (6th Edition):
Nirasay, S. (2017). Élaboration de membranes phospholipidiques supportées sur des surfaces nanopatternées en vue d'améliorer le criblage des médicaments. (Thesis). Université du Québec à Montréal. Retrieved from http://archipel.uqam.ca/10485/1/D3279.pdf
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Nirasay, Souryvanh. “Élaboration de membranes phospholipidiques supportées sur des surfaces nanopatternées en vue d'améliorer le criblage des médicaments.” 2017. Thesis, Université du Québec à Montréal. Accessed February 28, 2021.
http://archipel.uqam.ca/10485/1/D3279.pdf.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Nirasay, Souryvanh. “Élaboration de membranes phospholipidiques supportées sur des surfaces nanopatternées en vue d'améliorer le criblage des médicaments.” 2017. Web. 28 Feb 2021.
Vancouver:
Nirasay S. Élaboration de membranes phospholipidiques supportées sur des surfaces nanopatternées en vue d'améliorer le criblage des médicaments. [Internet] [Thesis]. Université du Québec à Montréal; 2017. [cited 2021 Feb 28].
Available from: http://archipel.uqam.ca/10485/1/D3279.pdf.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Nirasay S. Élaboration de membranes phospholipidiques supportées sur des surfaces nanopatternées en vue d'améliorer le criblage des médicaments. [Thesis]. Université du Québec à Montréal; 2017. Available from: http://archipel.uqam.ca/10485/1/D3279.pdf
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
McMaster University
27.
Truong, Tich.
THE SPICY, THE EVERLASTING AND THE UNEXPECTED: INVESTIGATING THREE COMPOUNDS THAT SUPPRESS MACROPHAGES AND MYOFIBROBLASTS TO REDUCE BIOMATERIAL-INDUCED FIBROSIS.
Degree: MASc, 2017, McMaster University
URL: http://hdl.handle.net/11375/20987
► Capsaicin, prostaglandin E2 (PGE2) and polydopamine (PDA) were used to target macrophage and myofibroblast activity to reduce biomaterial-induced fibrosis. The lifetime and efficacy of implantable…
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▼ Capsaicin, prostaglandin E2 (PGE2) and polydopamine (PDA) were used to target macrophage and myofibroblast activity to reduce biomaterial-induced fibrosis. The lifetime and efficacy of implantable biomedical devices are determined by the foreign body response. Immediately after implantation, proteins nonspecifically adsorb onto the material and initiate inflammation. Macrophages recruited to the site can differentiate into M1 and M2 phenotypes and upregulate inflammation and fibrosis which interferes with the intended function. M1 macrophages secrete pro-inflammatory mediators that induce chronic inflammation and promote myofibroblast differentiation while M2 macrophages are wound healing cells that suppress inflammation and regulate fibroblast activity. The fibrotic tissue is developed by myofibroblasts which produce collagen in an unregulated fashion. Collagen thickening and biomaterial encapsulation decreases efficacy and sensitive of biomedical devices. We investigated the in vitro and in vivo effects of capsaicin, PGE2 and polydopamine surface modification on macrophages and myofibroblasts. Capsaicin and PGE2 reduced poly(lactic-co-glycolic) acid (PLGA)-induced fibrosis by promoting M2 macrophage phenotype to secrete anti-inflammatory IL-10 and suppressing myofibroblast marker α-smooth muscle actin (α-SMA). Capsaicin decreased collagen by 40% and upregulated IL-10 secretion by 35% while PGE2 reduced collagen by 55% after 14 days of implantation and 40% less collagen after 42 days. PDA was used to bind an anti-fibrotic compound to the surface of a poly(dimethyl siloxane) (PDMS-PDA) to reduce fibrosis. However, PDMS-PDA controls gave an unexpected result by reducing fibrosis to the same extent as anti-fibrotic compound bound PDMS-
v
PDA. PDA modification reduced cellularity by 50% and significantly decreased collagen thickness by 30%. Overall, our results showed that biomaterial-induced fibrosis can be reduced by promoting M2 macrophage activity and inhibiting myofibroblast differentiation. This research demonstrates three compounds that have potential to reduce fibrosis and extend the lifetime and efficacy of implantable biomedical devices.
Thesis
Master of Applied Science (MASc)
Capsaicin, prostaglandin E2 (PGE2) and polydopamine were used to reduce scar tissue development around implanted polymers. Biomedical devices implanted in the body can undergo severe scar tissue formation, or fibrosis, and fail. Fibrosis is described by the accumulation of collagen and encapsulation of an implanted polymer. Macrophages regulate fibrosis by secreting pro-fibrotic compounds and myofibroblasts produce unregulated amounts of collagen. In this thesis, capsaicin, PGE2 and polydopamine were incorporated into implants to target macrophage and myofibroblast activity and reduce fibrosis in mice. Capsaicin and PGE2, released from a degradable polymer, altered macrophages to secrete anti-fibrotic compounds and decreased collagen by 40% and 55%, respectively. Polydopamine surface modified implants gave an unexpected result…
Advisors/Committee Members: Jones, Kim, Chemical Engineering.
Subjects/Keywords: capsaicin; macrophage phenotype; fibrosis; poly(lactic-co-glycolic) acid (PLGA); myofibroblast; inflammation; polydimethylsiloxane; polydopamine; fibrinogen; prostaglandin E2 (PGE2)
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APA ·
Chicago ·
MLA ·
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CSE |
Export
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Manager
APA (6th Edition):
Truong, T. (2017). THE SPICY, THE EVERLASTING AND THE UNEXPECTED: INVESTIGATING THREE COMPOUNDS THAT SUPPRESS MACROPHAGES AND MYOFIBROBLASTS TO REDUCE BIOMATERIAL-INDUCED FIBROSIS. (Masters Thesis). McMaster University. Retrieved from http://hdl.handle.net/11375/20987
Chicago Manual of Style (16th Edition):
Truong, Tich. “THE SPICY, THE EVERLASTING AND THE UNEXPECTED: INVESTIGATING THREE COMPOUNDS THAT SUPPRESS MACROPHAGES AND MYOFIBROBLASTS TO REDUCE BIOMATERIAL-INDUCED FIBROSIS.” 2017. Masters Thesis, McMaster University. Accessed February 28, 2021.
http://hdl.handle.net/11375/20987.
MLA Handbook (7th Edition):
Truong, Tich. “THE SPICY, THE EVERLASTING AND THE UNEXPECTED: INVESTIGATING THREE COMPOUNDS THAT SUPPRESS MACROPHAGES AND MYOFIBROBLASTS TO REDUCE BIOMATERIAL-INDUCED FIBROSIS.” 2017. Web. 28 Feb 2021.
Vancouver:
Truong T. THE SPICY, THE EVERLASTING AND THE UNEXPECTED: INVESTIGATING THREE COMPOUNDS THAT SUPPRESS MACROPHAGES AND MYOFIBROBLASTS TO REDUCE BIOMATERIAL-INDUCED FIBROSIS. [Internet] [Masters thesis]. McMaster University; 2017. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/11375/20987.
Council of Science Editors:
Truong T. THE SPICY, THE EVERLASTING AND THE UNEXPECTED: INVESTIGATING THREE COMPOUNDS THAT SUPPRESS MACROPHAGES AND MYOFIBROBLASTS TO REDUCE BIOMATERIAL-INDUCED FIBROSIS. [Masters Thesis]. McMaster University; 2017. Available from: http://hdl.handle.net/11375/20987
28.
LEWIS TAN HARK CHUAN.
SURFACE MODIFICATION OF METALLIC ORTHOPAEDIC IMPLANTS TO ENHANCE ANTI-FIBROTIC AND ANTI-INFLAMMATORY EFFECTS USING BMP-7 DERIVATIVES.
Degree: 2013, National University of Singapore
URL: http://scholarbank.nus.edu.sg/handle/10635/48865
Subjects/Keywords: fibrosis; cobalt-chromium; inflammation; BMP-7; polydopamine; osteogenesis
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APA ·
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Export
to Zotero / EndNote / Reference
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APA (6th Edition):
CHUAN, L. T. H. (2013). SURFACE MODIFICATION OF METALLIC ORTHOPAEDIC IMPLANTS TO ENHANCE ANTI-FIBROTIC AND ANTI-INFLAMMATORY EFFECTS USING BMP-7 DERIVATIVES. (Thesis). National University of Singapore. Retrieved from http://scholarbank.nus.edu.sg/handle/10635/48865
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
CHUAN, LEWIS TAN HARK. “SURFACE MODIFICATION OF METALLIC ORTHOPAEDIC IMPLANTS TO ENHANCE ANTI-FIBROTIC AND ANTI-INFLAMMATORY EFFECTS USING BMP-7 DERIVATIVES.” 2013. Thesis, National University of Singapore. Accessed February 28, 2021.
http://scholarbank.nus.edu.sg/handle/10635/48865.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
CHUAN, LEWIS TAN HARK. “SURFACE MODIFICATION OF METALLIC ORTHOPAEDIC IMPLANTS TO ENHANCE ANTI-FIBROTIC AND ANTI-INFLAMMATORY EFFECTS USING BMP-7 DERIVATIVES.” 2013. Web. 28 Feb 2021.
Vancouver:
CHUAN LTH. SURFACE MODIFICATION OF METALLIC ORTHOPAEDIC IMPLANTS TO ENHANCE ANTI-FIBROTIC AND ANTI-INFLAMMATORY EFFECTS USING BMP-7 DERIVATIVES. [Internet] [Thesis]. National University of Singapore; 2013. [cited 2021 Feb 28].
Available from: http://scholarbank.nus.edu.sg/handle/10635/48865.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
CHUAN LTH. SURFACE MODIFICATION OF METALLIC ORTHOPAEDIC IMPLANTS TO ENHANCE ANTI-FIBROTIC AND ANTI-INFLAMMATORY EFFECTS USING BMP-7 DERIVATIVES. [Thesis]. National University of Singapore; 2013. Available from: http://scholarbank.nus.edu.sg/handle/10635/48865
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
29.
SONG LINA.
ANTI-BIOFOULING PVDF MEMBRANES IMMOBILIZEED WITH TiO2 NANOPARTICLES VIA POLYDOPAMINE.
Degree: 2015, National University of Singapore
URL: http://scholarbank.nus.edu.sg/handle/10635/121990
Subjects/Keywords: PVDF; membrane fouling; biofouling; nanoparticle; titanium dioxide; polydopamine
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
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APA (6th Edition):
LINA, S. (2015). ANTI-BIOFOULING PVDF MEMBRANES IMMOBILIZEED WITH TiO2 NANOPARTICLES VIA POLYDOPAMINE. (Thesis). National University of Singapore. Retrieved from http://scholarbank.nus.edu.sg/handle/10635/121990
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
LINA, SONG. “ANTI-BIOFOULING PVDF MEMBRANES IMMOBILIZEED WITH TiO2 NANOPARTICLES VIA POLYDOPAMINE.” 2015. Thesis, National University of Singapore. Accessed February 28, 2021.
http://scholarbank.nus.edu.sg/handle/10635/121990.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
LINA, SONG. “ANTI-BIOFOULING PVDF MEMBRANES IMMOBILIZEED WITH TiO2 NANOPARTICLES VIA POLYDOPAMINE.” 2015. Web. 28 Feb 2021.
Vancouver:
LINA S. ANTI-BIOFOULING PVDF MEMBRANES IMMOBILIZEED WITH TiO2 NANOPARTICLES VIA POLYDOPAMINE. [Internet] [Thesis]. National University of Singapore; 2015. [cited 2021 Feb 28].
Available from: http://scholarbank.nus.edu.sg/handle/10635/121990.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
LINA S. ANTI-BIOFOULING PVDF MEMBRANES IMMOBILIZEED WITH TiO2 NANOPARTICLES VIA POLYDOPAMINE. [Thesis]. National University of Singapore; 2015. Available from: http://scholarbank.nus.edu.sg/handle/10635/121990
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
30.
BARBARA ELODIE ARIANE POINARD.
POLYDOPAMINE NANOPARTICLES AS A MUCOPENETRATIVE DRUG DELIVERY NANOCARRIER FOR BLADDER CANCER TREATMENT.
Degree: 2018, National University of Singapore
URL: http://scholarbank.nus.edu.sg/handle/10635/150963
Subjects/Keywords: Nanoparticles; Polydopamine; Bladder Cancer; Mucopenetration; Photodynamic therapy; Photothermal therapy
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APA ·
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APA (6th Edition):
POINARD, B. E. A. (2018). POLYDOPAMINE NANOPARTICLES AS A MUCOPENETRATIVE DRUG DELIVERY NANOCARRIER FOR BLADDER CANCER TREATMENT. (Thesis). National University of Singapore. Retrieved from http://scholarbank.nus.edu.sg/handle/10635/150963
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
POINARD, BARBARA ELODIE ARIANE. “POLYDOPAMINE NANOPARTICLES AS A MUCOPENETRATIVE DRUG DELIVERY NANOCARRIER FOR BLADDER CANCER TREATMENT.” 2018. Thesis, National University of Singapore. Accessed February 28, 2021.
http://scholarbank.nus.edu.sg/handle/10635/150963.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
POINARD, BARBARA ELODIE ARIANE. “POLYDOPAMINE NANOPARTICLES AS A MUCOPENETRATIVE DRUG DELIVERY NANOCARRIER FOR BLADDER CANCER TREATMENT.” 2018. Web. 28 Feb 2021.
Vancouver:
POINARD BEA. POLYDOPAMINE NANOPARTICLES AS A MUCOPENETRATIVE DRUG DELIVERY NANOCARRIER FOR BLADDER CANCER TREATMENT. [Internet] [Thesis]. National University of Singapore; 2018. [cited 2021 Feb 28].
Available from: http://scholarbank.nus.edu.sg/handle/10635/150963.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
POINARD BEA. POLYDOPAMINE NANOPARTICLES AS A MUCOPENETRATIVE DRUG DELIVERY NANOCARRIER FOR BLADDER CANCER TREATMENT. [Thesis]. National University of Singapore; 2018. Available from: http://scholarbank.nus.edu.sg/handle/10635/150963
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
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Open Access Theses and Dissertations
