subject:(Polyacetal)

University of Texas – Austin

1. Adams, Jacob Robert. Organic materials development for advanced lithographic applications.

Degree: PhD, Chemistry, 2009, University of Texas – Austin

URL: http://hdl.handle.net/2152/ETD-UT-2009-08-209

► The microelectronics industry strives for continued reduction in feature sizes to allow increased computing speed and power. This calls for continuous development of new materials.… (more)

Subjects/Keywords: Microelectronics; Lithography; 157 nm photolithography; Polyacetal

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APA (6^th Edition):

Adams, J. R. (2009). Organic materials development for advanced lithographic applications. (Doctoral Dissertation). University of Texas – Austin. Retrieved from http://hdl.handle.net/2152/ETD-UT-2009-08-209

Chicago Manual of Style (16^th Edition):

Adams, Jacob Robert. “Organic materials development for advanced lithographic applications.” 2009. Doctoral Dissertation, University of Texas – Austin. Accessed January 16, 2021. http://hdl.handle.net/2152/ETD-UT-2009-08-209.

MLA Handbook (7^th Edition):

Adams, Jacob Robert. “Organic materials development for advanced lithographic applications.” 2009. Web. 16 Jan 2021.

Vancouver:

Adams JR. Organic materials development for advanced lithographic applications. [Internet] [Doctoral dissertation]. University of Texas – Austin; 2009. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/2152/ETD-UT-2009-08-209.

Council of Science Editors:

Adams JR. Organic materials development for advanced lithographic applications. [Doctoral Dissertation]. University of Texas – Austin; 2009. Available from: http://hdl.handle.net/2152/ETD-UT-2009-08-209

Université de Bordeaux I

2. Liu, Na. Nouveaux polymères issus de la polymérisation par étapes organocatalysée de monomères aldéhydiques : polyaldols et polybenzoïnes linéaires et polyacétals hyperramifiés : New polymers synthesis by organocatalyzed step-growth polymerization of aldehydic monomers : polyaldols, linear polybenzoin and hyperbranched polyacetals.

Degree: Docteur es, Polymères, 2013, Université de Bordeaux I

URL: http://www.theses.fr/2013BOR15265

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A partir des mêmes briques élémentaires portant des fonctions aldéhydes et mettant en jeu des catalyseurs différents, trois types de nouveaux polymères ont été synthétisés… (more)

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A partir des mêmes briques élémentaires portant des fonctions aldéhydes et mettant en jeu des catalyseurs différents, trois types de nouveaux polymères ont été synthétisés par la polymérisation par étape dans ce travail. Dans la première partie, bis-cétone et bis-aldéhyde monomères ont directement polymérisé dans des conditions stoechiométriques par ce processus offrant polyaldols. Divers catalyseurs et des effets de la nature du solvant ont ensuite été étudiés. Dans la deuxième partie, nous avons travaillé sur la polymérisation organo-catalysée de monomères bis-aldéhydes par des précurseurs de carbènes N-hétérocycliques chiraux et achiraux pour synthétiser les polymères chiraux. Enfin, la directe polymérisation des monomères de type AB2 avec une fonction aldéhyde fournit une facile synthétique approche à polyacétals hyperbrramifiés portant nombreux périphéries aldehyiques. Ces polyacétals hyperramifiés sans défauts structuraux ont ensuit été introduirsé par des chaines de PEO par réaction de « PEGylation ». L’utilisation de la postpolymymérisation permet d’offre un large varité de la propriété du polymère, à l’aide ces périphéries aldéhydiques. Enplus, les polyacétals hyperramifiés sont dégradables, et facilement hydrolysés en milieu acide.

Using the same building blocks carrying aldehyde function with different catalysts, three types of new polymers were synthesized by step-growth polymerization in this work. In the fist part, bis-ketone and bis-aldehyde monomers have been directly polymerized under stoichiometric conditions by this process affording polyaldols. The effects of different catalysts and solvent nature have also been studied. In the second part, we have studied the organo-catalyzed polymerization of bis-aldehyde monomers by precursors of chiral and achiral N-heterocyclic carbene for synthesis of chiral polymer. Finally, polymerization of AB2-type monomers with one function of aldehyde provides a facile synthetic approach to hyperbranched polyacetals carrying numerous peripheral aldehydes. These defect free hyperbranched polyacetals have been introduced PEO chains by "PEGylation" reaction. A wide variety of other functional moieties could be introduced by postpolymerization with peripheral aldehydes. Besides, the hyperbranched polyacetals are degradable in essence, being readily hydrolyzed under acidic condition.

Advisors/Committee Members: Cramail, Henri (thesis director), Taton, Daniel (thesis director).

Subjects/Keywords: Polymérisation par étape; Organocatalyse; Monomères aldéhydiques; Polyaldols; Polybenzoïnes linéaires; Carbènes N-hétérocycliques; Polyacétals hyperramifiés; Dégradable par voie acide; Step-growth polymerization; Organocatalysis; Aldehydic monomer; Polyaldol; Linear polybenzoin; N-heterocyclic carbenes; Hyperbranched polyacetal; Acid degradable

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Liu, N. (2013). Nouveaux polymères issus de la polymérisation par étapes organocatalysée de monomères aldéhydiques : polyaldols et polybenzoïnes linéaires et polyacétals hyperramifiés : New polymers synthesis by organocatalyzed step-growth polymerization of aldehydic monomers : polyaldols, linear polybenzoin and hyperbranched polyacetals. (Doctoral Dissertation). Université de Bordeaux I. Retrieved from http://www.theses.fr/2013BOR15265

Chicago Manual of Style (16^th Edition):

Liu, Na. “Nouveaux polymères issus de la polymérisation par étapes organocatalysée de monomères aldéhydiques : polyaldols et polybenzoïnes linéaires et polyacétals hyperramifiés : New polymers synthesis by organocatalyzed step-growth polymerization of aldehydic monomers : polyaldols, linear polybenzoin and hyperbranched polyacetals.” 2013. Doctoral Dissertation, Université de Bordeaux I. Accessed January 16, 2021. http://www.theses.fr/2013BOR15265.

MLA Handbook (7^th Edition):

Liu, Na. “Nouveaux polymères issus de la polymérisation par étapes organocatalysée de monomères aldéhydiques : polyaldols et polybenzoïnes linéaires et polyacétals hyperramifiés : New polymers synthesis by organocatalyzed step-growth polymerization of aldehydic monomers : polyaldols, linear polybenzoin and hyperbranched polyacetals.” 2013. Web. 16 Jan 2021.

Vancouver:

Liu N. Nouveaux polymères issus de la polymérisation par étapes organocatalysée de monomères aldéhydiques : polyaldols et polybenzoïnes linéaires et polyacétals hyperramifiés : New polymers synthesis by organocatalyzed step-growth polymerization of aldehydic monomers : polyaldols, linear polybenzoin and hyperbranched polyacetals. [Internet] [Doctoral dissertation]. Université de Bordeaux I; 2013. [cited 2021 Jan 16]. Available from: http://www.theses.fr/2013BOR15265.

Council of Science Editors:

Liu N. Nouveaux polymères issus de la polymérisation par étapes organocatalysée de monomères aldéhydiques : polyaldols et polybenzoïnes linéaires et polyacétals hyperramifiés : New polymers synthesis by organocatalyzed step-growth polymerization of aldehydic monomers : polyaldols, linear polybenzoin and hyperbranched polyacetals. [Doctoral Dissertation]. Université de Bordeaux I; 2013. Available from: http://www.theses.fr/2013BOR15265

University of Florida

3. Pemba, Alexander Grey. Polyacetals from Bioderived Starting Materials as Potential Replacements for Commodity Packaging Plastics.

Degree: PhD, Chemistry, 2014, University of Florida

URL: https://ufdc.ufl.edu/UFE0046304

Subjects/Keywords: Acetals; Carbon; Flasks; Molecular weight; Monomers; Nitrogen; Polymerization; Polymers; Solvents; X ray spectrum; biorenewable; degradable; degradation; polyacetal; spiroacetal

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Pemba, A. G. (2014). Polyacetals from Bioderived Starting Materials as Potential Replacements for Commodity Packaging Plastics. (Doctoral Dissertation). University of Florida. Retrieved from https://ufdc.ufl.edu/UFE0046304

Chicago Manual of Style (16^th Edition):

Pemba, Alexander Grey. “Polyacetals from Bioderived Starting Materials as Potential Replacements for Commodity Packaging Plastics.” 2014. Doctoral Dissertation, University of Florida. Accessed January 16, 2021. https://ufdc.ufl.edu/UFE0046304.

MLA Handbook (7^th Edition):

Pemba, Alexander Grey. “Polyacetals from Bioderived Starting Materials as Potential Replacements for Commodity Packaging Plastics.” 2014. Web. 16 Jan 2021.

Vancouver:

Pemba AG. Polyacetals from Bioderived Starting Materials as Potential Replacements for Commodity Packaging Plastics. [Internet] [Doctoral dissertation]. University of Florida; 2014. [cited 2021 Jan 16]. Available from: https://ufdc.ufl.edu/UFE0046304.

Council of Science Editors:

Pemba AG. Polyacetals from Bioderived Starting Materials as Potential Replacements for Commodity Packaging Plastics. [Doctoral Dissertation]. University of Florida; 2014. Available from: https://ufdc.ufl.edu/UFE0046304

4. Heffernan, Michael John. Biodegradable polymeric delivery systems for protein subunit vaccines.

Degree: PhD, Biomedical Engineering, 2008, Georgia Tech

URL: http://hdl.handle.net/1853/24787

► The prevention and treatment of cancer and infectious diseases requires vaccines that can mediate cytotoxic T lymphocyte-based immunity. A promising strategy is protein subunit vaccines… (more)

▼ The prevention and treatment of cancer and infectious diseases requires vaccines that can mediate cytotoxic T lymphocyte-based immunity. A promising strategy is protein subunit vaccines composed of purified protein antigens and immunostimulatory adjuvants, such as Toll-like receptor (TLR) agonists. In this research, we developed two new biodegradable polymeric delivery vehicles for protein antigens and TLR agonists, as model vaccine delivery systems. This work was guided by the central hypothesis that an effective vaccine delivery system would have stimulus-responsive degradation and release, biodegradability into excretable non-acidic degradation products, and the ability to incorporate various TLR-inducing adjuvants. The first vaccine delivery system is a cross-linked polyion complex micelle which efficiently encapsulates proteins, DNA, and RNA. The micelle-based delivery system consists of a block copolymer of poly(ethylene glycol) (PEG) and poly(L-lysine), cross-linked by dithiopyridyl side groups to provide transport stability and intracellular release. The second delivery system consists of solid biodegradable microparticles encapsulating proteins, nucleic acids, and hydrophobic compounds. The microparticles are composed of pH-sensitive polyketals, which are a new family of hydrophobic, linear polymers containing backbone ketal linkages. Polyketals are synthesized via a new polymerization method based on the acetal exchange reaction and degrade into non-acidic, excretable degradation products. In addition, the technique of hydrophobic ion pairing was utilized to enhance the encapsulation of ovalbumin, DNA, and RNA in polyketal microparticles via a single emulsion method. Using in vitro and in vivo immunological models, we demonstrated that the micelle- and polyketal-based vaccine delivery systems enhanced the cross-priming of cytotoxic T lymphocytes. The model vaccines were composed of ovalbumin antigen and various TLR-inducing adjuvants including CpG-DNA, monophosphoryl lipid A, and dsRNA. The results demonstrate that the cross-linked micelles and polyketal microparticles have considerable potential as delivery systems for protein-based vaccines. Advisors/Committee Members: Dr. Niren Murthy (Committee Chair), Dr. Carson Meredith (Committee Member), Dr. Julia Babensee (Committee Member), Dr. Mark Prausnitz (Committee Member), Dr. Ravi Bellamkonda (Committee Member).

Subjects/Keywords: Vaccine delivery; Drug delivery; Microencapsulation; Nanospheres; Microspheres; Nanoparticles; Polyacetal; PH-responsive; TLR ligands; Poly(I)-poly(C); Acid-degradable; Vaccines; Polymeric drug delivery systems; Biodegradable plastics

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Heffernan, M. J. (2008). Biodegradable polymeric delivery systems for protein subunit vaccines. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/24787

Chicago Manual of Style (16^th Edition):

Heffernan, Michael John. “Biodegradable polymeric delivery systems for protein subunit vaccines.” 2008. Doctoral Dissertation, Georgia Tech. Accessed January 16, 2021. http://hdl.handle.net/1853/24787.

MLA Handbook (7^th Edition):

Heffernan, Michael John. “Biodegradable polymeric delivery systems for protein subunit vaccines.” 2008. Web. 16 Jan 2021.

Vancouver:

Heffernan MJ. Biodegradable polymeric delivery systems for protein subunit vaccines. [Internet] [Doctoral dissertation]. Georgia Tech; 2008. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1853/24787.

Council of Science Editors:

Heffernan MJ. Biodegradable polymeric delivery systems for protein subunit vaccines. [Doctoral Dissertation]. Georgia Tech; 2008. Available from: http://hdl.handle.net/1853/24787

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