subject:(Poly I poly C )

1. Ladeira costa claudio, Nuno filipe. GADD34 : Lien moléculaire entre la détection des pathogènes et les voies intégrées de réponses au stress : GADD34 : Linking pathogen detection with the integrated stress response pathways.

Degree: Docteur es, Sciences de la vie et de la sante, 2012, Aix Marseille Université

URL: http://www.theses.fr/2012AIXM4025

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Les cellules dendritiques (DCs) sont les plus efficaces cellules présentatrices d'antigène. La détection de motifs pathogènes, tel que lipopolysaccharides bactériens et ARNs double-brins (ARNdb) viraux,… (more)

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Les cellules dendritiques (DCs) sont les plus efficaces cellules présentatrices d'antigène. La détection de motifs pathogènes, tel que lipopolysaccharides bactériens et ARNs double-brins (ARNdb) viraux, par les DCs provoque leur maturation et induit de nombreux changements morphologiques et biochimiques permettant aux DCs d'acquérir leurs puissants fonctions activatrices des cellules T. Dans ce travail, les réponses des DCs à l'ARNdb ont été analysées. Nous avons montré que, en réponse à au poly I:C, un analogue synthétique des ARNdb, les DCs montent une réponse de stress intégré spécifique au cours de laquelle le facteur de transcription ATF4 et le cofacteur de la phosphatase 1, GADD34, sont exprimés. Les DCs activées par le poly I:C présentent un profil de transcrits similaire à ce qui est produit au cours d'une ‘unfolded protein response'. GADD34 est important pour contrebalancer la phosphorylation du facteur d'initiation de la synthèse protéique eIF2α par la kinase PKR au cours de l'activation des DCs. Contrairement aux fibroblastes embryonnaires murins, les DCs résistent à l'inhibition de la synthèse des protéines induite en réponse à la stimulation avec poly I:C. Néanmoins, l'expression de GADD34 n'a pas un impact majeur sur la synthèse protéique globale. Par contre, GADD34 a été démontré être absolument nécessaire à la production d'interféron du type I et d'IL-6 par les fibroblastes et les DCs en réponse à l'ARNdb. Cette observation a des implications importantes en liant la détection des pathogènes avec les voies intégrés de réponse au stress.

Dendritic cells (DCs) are the most important antigen presenting cells. In response to inflammatory stimulation, DCs display a distinct pattern of differentiation that exhibits specific mechanisms to control the immune response. In this work the responses to dsRNA were analyzed. We have shown that in response to a mimic of dsRNA, polyriboinosinic:polyribocytidylic acid (poly I:C), DCs mount a specific integrated stress response during which the transcription factor ATF4 and the growth arrest and DNA damage-inducible protein 34 (GADD34), a phosphatase 1 (PP1) cofactor, are expressed. GADD34 is important to counteract phosphorylation of eIF2α by PKR. In contrast to murine embryonic fibroblasts (MEFs), DCs resist to protein synthesis inhibition induced in response to cytosolic dsRNA. Nevertheless, GADD34 expression does not have a major impact on global protein synthesis. Importantly, GADD34 was shown to be absolutely required for type I-IFN and IL-6 production by MEFs and DCs in response to dsRNA. This observation has important implications in linking pathogen detection with the integrated stress response pathways. The importance of this link is further underlined by the extreme susceptibility of GADD34-deficient fibroblasts and neonate mice to Chikungunya virus infection.

Advisors/Committee Members: Pierre, Philippe (thesis director).

Subjects/Keywords: Cellules dendritiques; Gadd34; Poly I :C; EIF2α; Traduction; Dendritic cells; Gadd34; Poly I:C; EIF2α; Translation

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ladeira costa claudio, N. f. (2012). GADD34 : Lien moléculaire entre la détection des pathogènes et les voies intégrées de réponses au stress : GADD34 : Linking pathogen detection with the integrated stress response pathways. (Doctoral Dissertation). Aix Marseille Université. Retrieved from http://www.theses.fr/2012AIXM4025

Chicago Manual of Style (16^th Edition):

Ladeira costa claudio, Nuno filipe. “GADD34 : Lien moléculaire entre la détection des pathogènes et les voies intégrées de réponses au stress : GADD34 : Linking pathogen detection with the integrated stress response pathways.” 2012. Doctoral Dissertation, Aix Marseille Université. Accessed January 16, 2021. http://www.theses.fr/2012AIXM4025.

MLA Handbook (7^th Edition):

Ladeira costa claudio, Nuno filipe. “GADD34 : Lien moléculaire entre la détection des pathogènes et les voies intégrées de réponses au stress : GADD34 : Linking pathogen detection with the integrated stress response pathways.” 2012. Web. 16 Jan 2021.

Vancouver:

Ladeira costa claudio Nf. GADD34 : Lien moléculaire entre la détection des pathogènes et les voies intégrées de réponses au stress : GADD34 : Linking pathogen detection with the integrated stress response pathways. [Internet] [Doctoral dissertation]. Aix Marseille Université 2012. [cited 2021 Jan 16]. Available from: http://www.theses.fr/2012AIXM4025.

Council of Science Editors:

Ladeira costa claudio Nf. GADD34 : Lien moléculaire entre la détection des pathogènes et les voies intégrées de réponses au stress : GADD34 : Linking pathogen detection with the integrated stress response pathways. [Doctoral Dissertation]. Aix Marseille Université 2012. Available from: http://www.theses.fr/2012AIXM4025

2. Zeis, Marios. Πειραματική διερεύνηση της προστατευτικής δράσης της ιντερφερόνης στην οξεία νεφροτοξικότητα που προκαλείται από κυκλοσπορίνη.

Degree: 2011, National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ)

URL: http://hdl.handle.net/10442/hedi/33078

► We induced in rabbits acute nephrotoxicity by injecting high doses of CsA, aiming to clarify whether CsA has a nephrotoxic effect by pre- and post-glomerular… (more)

Subjects/Keywords: Οξεία νεφροτοξικότητα από κυκλοσπορίνη; Ιντερφερόνη; Ενδογενής ιντερφερόνη; Κυκλοσπορίνη; Οξεία νεφροτοξικότητα; Cyclosporine induced acute nephrotoxicity; Endogenous interferon; Poly I; Poly C; Cyclosporine; CsA; Interferon; Poly I:C; Acute nephrotoxicity

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Zeis, M. (2011). Πειραματική διερεύνηση της προστατευτικής δράσης της ιντερφερόνης στην οξεία νεφροτοξικότητα που προκαλείται από κυκλοσπορίνη. (Thesis). National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Retrieved from http://hdl.handle.net/10442/hedi/33078

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Zeis, Marios. “Πειραματική διερεύνηση της προστατευτικής δράσης της ιντερφερόνης στην οξεία νεφροτοξικότητα που προκαλείται από κυκλοσπορίνη.” 2011. Thesis, National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Accessed January 16, 2021. http://hdl.handle.net/10442/hedi/33078.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Zeis, Marios. “Πειραματική διερεύνηση της προστατευτικής δράσης της ιντερφερόνης στην οξεία νεφροτοξικότητα που προκαλείται από κυκλοσπορίνη.” 2011. Web. 16 Jan 2021.

Vancouver:

Zeis M. Πειραματική διερεύνηση της προστατευτικής δράσης της ιντερφερόνης στην οξεία νεφροτοξικότητα που προκαλείται από κυκλοσπορίνη. [Internet] [Thesis]. National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ); 2011. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/10442/hedi/33078.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Zeis M. Πειραματική διερεύνηση της προστατευτικής δράσης της ιντερφερόνης στην οξεία νεφροτοξικότητα που προκαλείται από κυκλοσπορίνη. [Thesis]. National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ); 2011. Available from: http://hdl.handle.net/10442/hedi/33078

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Texas Southwestern Medical Center

3. Castro Rojas, Cyd Marie. Poly I:C Induced Gene Ablation Negates Potentially Beneficial Effects of A4-Integrin Depletion on Experimental Autoimmune Encephalomyelitis.

Degree: 2016, University of Texas Southwestern Medical Center

URL: http://hdl.handle.net/2152.5/5309

► In the experimental autoimmune encephalomyelitis (EAE) murine model of multiple sclerosis, leukocytes transmigrate through the blood brain barrier into the perivascular space and enter the… (more)

▼ In the experimental autoimmune encephalomyelitis (EAE) murine model of multiple sclerosis, leukocytes transmigrate through the blood brain barrier into the perivascular space and enter the parenchyma of the central nervous system (CNS). This entry is facilitated by the interaction of very late activation antigen-4 (α4β1-integrin) on activated T cells with vascular cell adhesion molecule-1 that is expressed by inflamed endothelium. It has been demonstrated that α4-integrin antagonism in multiple sclerosis patients can be significantly beneficial, but it can also lead to detrimental CNS infections due to impairing of immune surveillance. In this work, we seek to understand cell type specificity of α4-integrin antagonism in order to improve immune competence in the CNS. We generated the conditional knock out mouse strain Mx1.Cre+ α4-integrinfl/fl on the C57BL/6 background that enables α4-integrin gene ablation by the Cre-lox recombination system upon poly I:C treatment. We hypothesize that antagonism of α4-integrin diminishes immunocompetence within the CNS by differentially affecting leukocyte subsets. In order to test this hypothesis, we actively and passively induced EAE on Mx1.Cre+ α4-integrinfl/fl. We observed that disease susceptibility and severity in poly I:C treated Mx1.Cre+ α4-integrinfl/fl mice were similar to that of wild type (WT), but the disease onset was significantly delayed. Additionally, while there was decreased migratory capabilities of CD45+ splenocytes from Mx1.Cre+α4-integrinfl/fl mice, the absolute number and composition of leukocytes in the CNS of EAE mice was similar in WT and poly I:C treated Mx1.Cre+ α4-integrinfl/fl mice. The presence of Evans Blue dye in the parenchyma of poly I:C treated mice suggest a role of poly I:C in this migratory effect. On the other hand, adoptively transferred cells from poly I:C treated Mx1.Cre+ α4-integrinfl/fl mice did not transfer EAE disease into WT. Based on these data, we concluded that Mx1.Cre+ α4-integrinfl/fl strain is limited to study the role of α4-integrin ablation on immunocompetence, however it is successful for the generation of α4-integrin deficient leukocytes. Finally, we determined optimization techniques for CNS leukocyte isolation that can be of benefit for future analyses. Advisors/Committee Members: Street, Nancy E., Stüve, Olaf, Stowe, Ann, Pasare, Chandrashekhar.

Subjects/Keywords: Central Nervous System; Encephalomyelitis, Autoimmune, Experimental; Integrin alpha4; Integrin alpha4beta1; Poly I-C

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Castro Rojas, C. M. (2016). Poly I:C Induced Gene Ablation Negates Potentially Beneficial Effects of A4-Integrin Depletion on Experimental Autoimmune Encephalomyelitis. (Thesis). University of Texas Southwestern Medical Center. Retrieved from http://hdl.handle.net/2152.5/5309

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Castro Rojas, Cyd Marie. “Poly I:C Induced Gene Ablation Negates Potentially Beneficial Effects of A4-Integrin Depletion on Experimental Autoimmune Encephalomyelitis.” 2016. Thesis, University of Texas Southwestern Medical Center. Accessed January 16, 2021. http://hdl.handle.net/2152.5/5309.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Castro Rojas, Cyd Marie. “Poly I:C Induced Gene Ablation Negates Potentially Beneficial Effects of A4-Integrin Depletion on Experimental Autoimmune Encephalomyelitis.” 2016. Web. 16 Jan 2021.

Vancouver:

Castro Rojas CM. Poly I:C Induced Gene Ablation Negates Potentially Beneficial Effects of A4-Integrin Depletion on Experimental Autoimmune Encephalomyelitis. [Internet] [Thesis]. University of Texas Southwestern Medical Center; 2016. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/2152.5/5309.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Castro Rojas CM. Poly I:C Induced Gene Ablation Negates Potentially Beneficial Effects of A4-Integrin Depletion on Experimental Autoimmune Encephalomyelitis. [Thesis]. University of Texas Southwestern Medical Center; 2016. Available from: http://hdl.handle.net/2152.5/5309

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Texas Southwestern Medical Center

4. Bresson, Stefan. The Role of the Human Nuclear Poly(A) Binding Protein in RNA Decay.

Degree: 2015, University of Texas Southwestern Medical Center

URL: http://hdl.handle.net/2152.5/4108

► Control of nuclear RNA stability is an important determinant of gene expression, but the factors involved in nuclear RNA decay remain largely unknown in higher… (more)

Subjects/Keywords: Cell Nucleus; Poly A; Poly(A)-Binding Protein I; RNA Stability

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Bresson, S. (2015). The Role of the Human Nuclear Poly(A) Binding Protein in RNA Decay. (Thesis). University of Texas Southwestern Medical Center. Retrieved from http://hdl.handle.net/2152.5/4108

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Bresson, Stefan. “The Role of the Human Nuclear Poly(A) Binding Protein in RNA Decay.” 2015. Thesis, University of Texas Southwestern Medical Center. Accessed January 16, 2021. http://hdl.handle.net/2152.5/4108.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Bresson, Stefan. “The Role of the Human Nuclear Poly(A) Binding Protein in RNA Decay.” 2015. Web. 16 Jan 2021.

Vancouver:

Bresson S. The Role of the Human Nuclear Poly(A) Binding Protein in RNA Decay. [Internet] [Thesis]. University of Texas Southwestern Medical Center; 2015. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/2152.5/4108.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bresson S. The Role of the Human Nuclear Poly(A) Binding Protein in RNA Decay. [Thesis]. University of Texas Southwestern Medical Center; 2015. Available from: http://hdl.handle.net/2152.5/4108

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Rochester

5. Boschi, Nicole M. The Role of Poly(c)-binding Proteins in the Post-transcriptional Control of Tyrosine Hydroxylase mRNA.

Degree: PhD, 2014, University of Rochester

URL: http://hdl.handle.net/1802/28981

► Poly(c)-binding proteins (PCBPs) are RNA and single-stranded DNA binding proteins known to be involved in a variety of post-transcriptional control pathways. Among the diverse functions… (more)

▼ Poly(c)-binding proteins (PCBPs) are RNA and single-stranded DNA binding proteins known to be involved in a variety of post-transcriptional control pathways. Among the diverse functions of these proteins is the interaction with a 27 nucleotide pyrimidine-rich domain within the 3‘UTR of tyrosine hydroxylase (TH) mRNA. Mutations to this domain result in decreased stability of TH mRNA, and it has been postulated that PCBPs play key roles in maintaining TH mRNA stability and in regulating TH mRNA translation. In order to further characterize the role of PCBPs in the post-transcriptional regulation of TH, we examined the tissue distribution as well as the subcellular localization of these proteins. Fluorescent immunohistochemistry and confocal microscopy was used to analyze the distribution of PCBPs in TH-positive cells of the rat midbrain, locus coeruleus, and adrenal gland. PCBP 1 was not found in TH-positive cell bodies of the substantia nigra pars compacta (SNc), however this protein was present in TH-positive cell processes extending into the substantia niga pars reticulata (SNr). In contrast, PCBPs 2, 3, and 4 were found in select cell bodies of the SNc as well as in the TH-positive fibers extending into the SNr. PCBP 3 was found in TH-positive cell bodies of the locus coeruleus, however PCBPs 1, 2, and 4 were not. Finally, all four isoforms were found in the adrenal with PCBP1 exhibiting a stronger staining pattern in the medulla relative to the surrounding cortex. PCBPs 2, 3, and 4 appear to be distributed equally in both the cortex. PCBP3 immunoreactivity was observed in the adrenal medulla, however this isoform appeared to be present in a lower concentration relative to PCBP1. A number of previous studies have shown that PCBP isoforms 1, 2, and 4 are widely distributed throughout the cell and that they shuttle between the nucleus and cytoplasm. However, PCBPs have not yet been shown to associate with specific cytoplasmic organelles. Given that PCBPs appear to modulate the stability and translation of TH mRNA, we have speculated that PCBPs are localized to cellular compartments that are involved in translational silencing and mRNA degradation. Recently, Fujimura et. al. (2009) have demonstrated through immunofluorescence studies in HeLa and Neuro2a cell lines that PCBP2 colocalizes with a subset of processing bodies (p-bodies). These cytoplasmic foci contain mRNA decay factors and translational repressors and are known to be involved in mRNA degradation and translation silencing. Based on these findings, we tested whether PCBPs co-localize with p-bodies markers in catecholaminergic cell lines. Mouse mesencephalon/neuroblastoma hybridoma MN9D cells were immunofluorescently stained with antibodies directed towards PCBPs 1, 2, and 3, as well as known p-body markers. Confocal microscopy revealed that PCBPs apparently co-localize with a subset of p-bodies in MN9D cells. These findings may provide insight into the role of these RNA binding proteins in catecholaminergic cells and into…

Subjects/Keywords: Poly(c)-Binding Protein; Tyrosine Hydroxylase

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Boschi, N. M. (2014). The Role of Poly(c)-binding Proteins in the Post-transcriptional Control of Tyrosine Hydroxylase mRNA. (Doctoral Dissertation). University of Rochester. Retrieved from http://hdl.handle.net/1802/28981

Chicago Manual of Style (16^th Edition):

Boschi, Nicole M. “The Role of Poly(c)-binding Proteins in the Post-transcriptional Control of Tyrosine Hydroxylase mRNA.” 2014. Doctoral Dissertation, University of Rochester. Accessed January 16, 2021. http://hdl.handle.net/1802/28981.

MLA Handbook (7^th Edition):

Boschi, Nicole M. “The Role of Poly(c)-binding Proteins in the Post-transcriptional Control of Tyrosine Hydroxylase mRNA.” 2014. Web. 16 Jan 2021.

Vancouver:

Boschi NM. The Role of Poly(c)-binding Proteins in the Post-transcriptional Control of Tyrosine Hydroxylase mRNA. [Internet] [Doctoral dissertation]. University of Rochester; 2014. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1802/28981.

Council of Science Editors:

Boschi NM. The Role of Poly(c)-binding Proteins in the Post-transcriptional Control of Tyrosine Hydroxylase mRNA. [Doctoral Dissertation]. University of Rochester; 2014. Available from: http://hdl.handle.net/1802/28981

Delft University of Technology

6. Kołtowska, P.D. (author). Development of poly-Si(Cx) passivating contacts for high efficient c-Si based solar cells.

Degree: 2020, Delft University of Technology

URL: http://resolver.tudelft.nl/uuid:5e9bd021-3992-45ba-ad12-d5674119b572

► Carrier-selective passivating contacts (CSPC) are very promising contact structures for highly efficient silicon solar cell. They provide passivation of silicon surface and high carrier selectivity.… (more)

▼ Carrier-selective passivating contacts (CSPC) are very promising contact structures for highly efficient silicon solar cell. They provide passivation of silicon surface and high carrier selectivity. So far, superior results have been achieved through the use of a stack of poly-Si with SiO2. The objective of this project is the optimization of an alternative passivation stack based on carbon alloyed poly-Si (poly-SiCx). The alloy is selected since carbon provides improved material resilience against blistering and wet-chemical stability in commonly used chemicals in the silicon industry. The optimized poly-SiCx contacts are implemented in fornt back contacted (FBC) solar cell. We improve the passivation quality of SiOx/poly-SiCx contacts optimizing several parameters. Our main focus is on the buffer layer optimization and its deposition methods comparing LPCVD and PECVD technique. We also turn our attention to identify the optimum annealing temperature and thickness of doped layers. Finally, we focus on the influence of the different capping layer composition on hydrogeneation process. With the optimization of the annealing temperature, and thickness of (i)a-Si layer deposited by LPCVD, we obtain high passivation quality on cell precursor structure: i-Voc of 713 mV, τeff of 2.14 ms and Jo of 9.5 fA/cm2. On the contrary, during the optimization of buffer layer deposited by PECVD, we firstly focus on the material properties and the bonds present in the deposited layers to minimize the hydrogen contact. After the optimization of the (i)a-Si:H layer thickness, deposition parameters and annealing temperature on (p)poly-SiCx symmetrical sample, we obtain the remarking results: i-Voc of 681 mV, τeff of 1.15 ms and Jo of 31.3 fA/cm2. The potential of SiOx/poly-SiCx passivation contacts is checked on the device level of FBC solar cells. On FBC solar cells with buffer layer deposited by the PECVD, after an effective post annealing of the cell performed at a temperature of 350°C, we achieve the remarking parameters; Voc of 659 mV, Jsc of 34.36 mA/cm2, FF of 77.58 % and ηact of 17.56 %. We check also the the influence of different SiNx capping layers on the hydrogenation process. We obtain the best results on the FBC solar cell on which the capping layer is stoichiometric. These results, after the high-temperature port annealing, are Voc of 690 mV, Jsc of 36.18 mA/cm2, FF of 80.38 %, and ηact of 20.06 %. These are also the best FBC poly-SiCx results which we have obtained in this project. The application of SiOx/poly-SiCx passivation contacts is investigated also in terms of the IBC solar cell concept. We proposed two alternative fabrication methods based on photolithography, which is crucial for contact formation of IBC solar cells. One of the fabrication methods focuses on a buffer layer deposited by LPCVD as this layer is of higher quality and homogeneity than the interlayer deposited by PECVD. The second developed method focuses on the buffer layer deposited by LPCVD and PECVD. Despite the lower passivation quality… Advisors/Committee Members: Mazzarella, L. (mentor), Isabella, O. (graduation committee), Delft University of Technology (degree granting institution).

Subjects/Keywords: passivating contact; poly-SiCx; c-Si

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Kołtowska, P. D. (. (2020). Development of poly-Si(Cx) passivating contacts for high efficient c-Si based solar cells. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:5e9bd021-3992-45ba-ad12-d5674119b572

Chicago Manual of Style (16^th Edition):

Kołtowska, P D (author). “Development of poly-Si(Cx) passivating contacts for high efficient c-Si based solar cells.” 2020. Masters Thesis, Delft University of Technology. Accessed January 16, 2021. http://resolver.tudelft.nl/uuid:5e9bd021-3992-45ba-ad12-d5674119b572.

MLA Handbook (7^th Edition):

Kołtowska, P D (author). “Development of poly-Si(Cx) passivating contacts for high efficient c-Si based solar cells.” 2020. Web. 16 Jan 2021.

Vancouver:

Kołtowska PD(. Development of poly-Si(Cx) passivating contacts for high efficient c-Si based solar cells. [Internet] [Masters thesis]. Delft University of Technology; 2020. [cited 2021 Jan 16]. Available from: http://resolver.tudelft.nl/uuid:5e9bd021-3992-45ba-ad12-d5674119b572.

Council of Science Editors:

Kołtowska PD(. Development of poly-Si(Cx) passivating contacts for high efficient c-Si based solar cells. [Masters Thesis]. Delft University of Technology; 2020. Available from: http://resolver.tudelft.nl/uuid:5e9bd021-3992-45ba-ad12-d5674119b572

Universidade do Rio Grande do Sul

7. Rosa, Eduarda Dias da. Determinação dos efeitos da suplementação de ômega-3 em um modelo neurodesenvolvimental de esquizofrenia induzido por poly(I:C) em ratos neonatos.

Degree: 2018, Universidade do Rio Grande do Sul

URL: http://hdl.handle.net/10183/180238

► A hipótese neurodesenvolvimental da esquizofrenia (SZ) tem origem numa perturbação do desenvolvimento ou maturação encefálica no período perinatal. Nesse contexto, objetivo deste trabalho foi avaliar… (more)

▼ A hipótese neurodesenvolvimental da esquizofrenia (SZ) tem origem numa perturbação do desenvolvimento ou maturação encefálica no período perinatal. Nesse contexto, objetivo deste trabalho foi avaliar o efeito da suplementação com ômega-3 (ω-3) em dois diferentes períodos de vida (período de crescimento fetal e durante a adolescência) em parâmetros comportamentais e bioquímicos em um modelo de desafio imune neonatal induzido por ácido poliinosínico:policitidílico (Poly(I:C)). Para isso, fêmeas wistar grávidas foram divididas em dois grupos para o tratamento de prevenção a partir do 16° ao 21º dia de gestação: um grupo recebeu ω-3 na dose de 0,8g/Kg via gavagem (grupo O), e o outro recebeu Tween (grupo T) na mesma dose e via. Após o nascimento, do 5º ao 7º dia pós-natal (PN) cada grupo de recém nascidos foi subdivido em dois grupos: um recebeu poly(I:C) na dose de 2mg/kg (grupo OP ou TP) e outro recebeu salina na dose 1 ml/kg (grupo OS ou TS), ambos via intraperitoneal. Na adolescência, do 30º ao 44º dia PN, os animais receberam o segundo tratamento de prevenção com ω-3, seguindo a mesma suplementação da gestação: com ω-3 (grupo OPO, TPO e TSO) ou Tween (grupo OPT, OST,TPT e TST)). No total, foram 7 grupos de tratamento (n~15 animais/grupo): TST, TPT, TSO, TPO, OST, OPT e OPO. No 45º dia PN foram realizados os testes comportamentais de Y-maze, campo aberto e interação social (three-chamber sociability and social novelty). Ao final foi realizada a eutanásia dos animais seguida da a coleta do sangue troncular e dissecação das estruturas cerebrais - córtex pré-frontal (CPF) e hipocampo (HC). O fator neurotrófico derivado do encéfalo (BDNF) e o estresse oxidativo, através das substâncias reativas ao ácido tiobarbitúrico (TBARS) e glutationa peroxidase (GPx), foram avaliadas no soro e nas estruturas cerebrais Os resultados foram expressos em mediana e intervalo interquartil (IQR). A análise foi realizada por Mann-Whitney U para comparações entre dois grupos (TST x TPT) e, para comparações múltiplas, empregou-se Kruskal-Wallis. Os resultados mostram que a administração neonatal de poly(I:C) foi capaz de induzir um comprometimento significativo na interação social e no interesse por novos conspecificos quando comparado ao controle (TST), sendo estes comportamentos considerados como um sintoma negativos da SZ. O desafio imune também aumentou significativamente a peroxidação lipídica no HC. A associação de suplementação ω-3 durante o crescimento fetal e durante a adolescência (OPO) foi capaz de proteger os animais de déficits de interesse social quando comparados ao grupo TPT. Além disso, apresentou níveis séricos significativamente elevados de BDNF e níveis mais baixos de peroxidação lipídica no HC do que o grupo TPT. Em conclusão, os resultados do presente trabalho mostram de forma inédita o efeito benéfico da suplementação subsequente com ω-3 em dois períodos distintos da vida de ratos submetidos a um modelo neurodesenvolvimental de SZ. Embora os mecanismos por trás desses resultados não sejam totalmente elucidados, o… Advisors/Committee Members: Gama, Clarissa Severino.

Subjects/Keywords: Schizophrenia; Ácidos graxos ômega-3; Social interaction; Esquizofrenia; Poli I-C; Neonatal immune challenge; Sistema imunológico : Fisiopatologia; Poly(I:C); Omega-3

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Rosa, E. D. d. (2018). Determinação dos efeitos da suplementação de ômega-3 em um modelo neurodesenvolvimental de esquizofrenia induzido por poly(I:C) em ratos neonatos. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/180238

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Rosa, Eduarda Dias da. “Determinação dos efeitos da suplementação de ômega-3 em um modelo neurodesenvolvimental de esquizofrenia induzido por poly(I:C) em ratos neonatos.” 2018. Thesis, Universidade do Rio Grande do Sul. Accessed January 16, 2021. http://hdl.handle.net/10183/180238.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Rosa, Eduarda Dias da. “Determinação dos efeitos da suplementação de ômega-3 em um modelo neurodesenvolvimental de esquizofrenia induzido por poly(I:C) em ratos neonatos.” 2018. Web. 16 Jan 2021.

Vancouver:

Rosa EDd. Determinação dos efeitos da suplementação de ômega-3 em um modelo neurodesenvolvimental de esquizofrenia induzido por poly(I:C) em ratos neonatos. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2018. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/10183/180238.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Rosa EDd. Determinação dos efeitos da suplementação de ômega-3 em um modelo neurodesenvolvimental de esquizofrenia induzido por poly(I:C) em ratos neonatos. [Thesis]. Universidade do Rio Grande do Sul; 2018. Available from: http://hdl.handle.net/10183/180238

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

8. Speers, Luke. Peptide-loaded, shear sensitive hydrogel as a novel topical delivery system for wound management and repair.

Degree: PhD, 2018, Ulster University

URL: https://ulster.pure.elsevier.com/en/studentTheses/e832ebb0-fac3-4b0b-aa7c-ebbb8e25e59f ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.793622

► The use of pharmaceutically active peptides and proteins has increased significantly over the last 30 years. Topical delivery of growth factors to chronic wounds to… (more)

▼ The use of pharmaceutically active peptides and proteins has increased significantly over the last 30 years. Topical delivery of growth factors to chronic wounds to enhance wound management and repair have been of particular interest. The aim of the work in this thesis was to evaluate the ability of the PVA-borate hydrogel formulation to deliver biologically active protein payloads. The unique viscoelastic properties of PVA-borate hydrogels are advantageous for application to wounds. The hydrogel can flow into the wound crevasses providing maximal surface area for drug delivery. Yet, they maintain enough cohesive integrity of its cross-linked network to allow for complete and intact removal from the wound, without causing any trauma to newly formed tissue. The ability of the PVA-borate hydrogel to maintain a moist environment and also absorb small volumes of exudate from low exuding wounds also aids wound healing. Several model payloads (BSA, haemoglobin, trypsin and pepsin) were incorporated into the hydrogel. These proteins where found to change the viscoelastic properties of the PVA-borate hydrogel, but, were released in a sustained manner from the hydrogel without undergoing any degradation. This investigation indicated that the PVA-borate hydrogel is capable of providing a sustained release of protein payloads with certain physical and chemical characteristics. Insulin-like growth factor-1 (IGF-1) was incorporated into the hydrogel and found not to effect the viscoelastic properties of the hydrogel. In vitro release studies confirmed that the hydrogel provided a sustained release of IGF-1, which had maintained its biological activity and not experienced any degradation. Cell culture studies confirmed that IGF-1-loaded PVA-borate hydrogels can stimulate fibroblast and keratinocyte migration and proliferation. Therefore, the work in this thesis demonstrates that IGF-1-loaded hydrogels may have a beneficial use in the management and repair of chronic and recalcitrant wounds.

Subjects/Keywords: PVA; Poly (vinyl alcohol); Borate; IGF-I

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Speers, L. (2018). Peptide-loaded, shear sensitive hydrogel as a novel topical delivery system for wound management and repair. (Doctoral Dissertation). Ulster University. Retrieved from https://ulster.pure.elsevier.com/en/studentTheses/e832ebb0-fac3-4b0b-aa7c-ebbb8e25e59f ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.793622

Chicago Manual of Style (16^th Edition):

Speers, Luke. “Peptide-loaded, shear sensitive hydrogel as a novel topical delivery system for wound management and repair.” 2018. Doctoral Dissertation, Ulster University. Accessed January 16, 2021. https://ulster.pure.elsevier.com/en/studentTheses/e832ebb0-fac3-4b0b-aa7c-ebbb8e25e59f ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.793622.

MLA Handbook (7^th Edition):

Speers, Luke. “Peptide-loaded, shear sensitive hydrogel as a novel topical delivery system for wound management and repair.” 2018. Web. 16 Jan 2021.

Vancouver:

Speers L. Peptide-loaded, shear sensitive hydrogel as a novel topical delivery system for wound management and repair. [Internet] [Doctoral dissertation]. Ulster University; 2018. [cited 2021 Jan 16]. Available from: https://ulster.pure.elsevier.com/en/studentTheses/e832ebb0-fac3-4b0b-aa7c-ebbb8e25e59f ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.793622.

Council of Science Editors:

Speers L. Peptide-loaded, shear sensitive hydrogel as a novel topical delivery system for wound management and repair. [Doctoral Dissertation]. Ulster University; 2018. Available from: https://ulster.pure.elsevier.com/en/studentTheses/e832ebb0-fac3-4b0b-aa7c-ebbb8e25e59f ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.793622

9. Packard, Amy Elizabeth Bruestle. Studies on poly-ICLC treatment as a potent neuroprotective therapy against ischemic brain injury.

Degree: PhD, 2011, Oregon Health Sciences University

URL: doi:10.6083/M4QV3JJW ; http://digitalcommons.ohsu.edu/etd/745

Subjects/Keywords: Cerebrovascular disease; Interferon; poly-ICLC; CpG-oligonucleotide; Stroke; Poly I-C; Ischemic Preconditioning; Oligodeoxyribonucleotides; Interferon Type I

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Packard, A. E. B. (2011). Studies on poly-ICLC treatment as a potent neuroprotective therapy against ischemic brain injury. (Doctoral Dissertation). Oregon Health Sciences University. Retrieved from doi:10.6083/M4QV3JJW ; http://digitalcommons.ohsu.edu/etd/745

Chicago Manual of Style (16^th Edition):

Packard, Amy Elizabeth Bruestle. “Studies on poly-ICLC treatment as a potent neuroprotective therapy against ischemic brain injury.” 2011. Doctoral Dissertation, Oregon Health Sciences University. Accessed January 16, 2021. doi:10.6083/M4QV3JJW ; http://digitalcommons.ohsu.edu/etd/745.

MLA Handbook (7^th Edition):

Packard, Amy Elizabeth Bruestle. “Studies on poly-ICLC treatment as a potent neuroprotective therapy against ischemic brain injury.” 2011. Web. 16 Jan 2021.

Vancouver:

Packard AEB. Studies on poly-ICLC treatment as a potent neuroprotective therapy against ischemic brain injury. [Internet] [Doctoral dissertation]. Oregon Health Sciences University; 2011. [cited 2021 Jan 16]. Available from: doi:10.6083/M4QV3JJW ; http://digitalcommons.ohsu.edu/etd/745.

Council of Science Editors:

Packard AEB. Studies on poly-ICLC treatment as a potent neuroprotective therapy against ischemic brain injury. [Doctoral Dissertation]. Oregon Health Sciences University; 2011. Available from: doi:10.6083/M4QV3JJW ; http://digitalcommons.ohsu.edu/etd/745

NSYSU

10. Chang, Shuo-Fu. Production and characterization of polyclonal antibody against Epinephelus coioides retinoic acid inducible gene-I.

Degree: Master, Biological Sciences, 2013, NSYSU

URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0327113-142030

► Orange-spotted Grouper (Epinephelus coioides) is one of the important economically farmed fish in Taiwan. However, grouper aquaculture in Taiwan has a serious problem of infection,… (more)

▼ Orange-spotted Grouper (Epinephelus coioides) is one of the important economically farmed fish in Taiwan. However, grouper aquaculture in Taiwan has a serious problem of infection, especially in grouper larvae breeding stage. The infection resulted in very high mortality, which causes massive economic loss. Therefore, early detection of pathogen is critical to prevent epidemic outbreak. Retinoic acid inducible gene-I (RIG-I) is an intracellular receptor recognizing dsRNA virus. Upon dsRNA virus infection, RIG-I is induced and over-expressed in protein level that mediating type I Interferon (IFNs) antiviral signaling. In this study, total RNA extracted from fertilized eggs of Epinephelus coioides was extracted for the reverse transcription-polymerase chain reaction (RT-PCR) amplification of 432 bp cDNA encoding regulatory domain (RD) of RIG-I protein. The amplified cDNA fragment was then cloned into pQE32 for the prokaryotic expression of 17 kDa His-tagged RIG-I (His-RIG-I-RD) fusion protein. His-RIG-I-RD fusion protein was purified for immunization of New Zealand white rabbit to produce antiserum against RIG-I protein. Our Western blot result confirmed the specificity of antiserum for recognizing 0.01 Î¼g His-RIG-I-RD fusion protein at 1:5000 dilution. In addition, 0.02 Î¼g of immunogen His-RIG-I-RD fusion protein can be readily detected at 1:25000 dilution. Furthermore, this antiserum could detect the increase of a 72 kDa protein in lysate prepared from head kidney of dsRNA viral mimic poly(I:C) injected Epinephelus coioides, but not in uninjected control fish. The immunostaining results of frozen head kidney sections also revealed the RIG-I immunoreactivity using this antiserum. RIG-I protein immunoreactivity was prominently increased in melanomacrophage center (MMC) of head kidney from poly(I:C) injected fish compared to that of uninjected control fish. In summary, we have generated a specific antiserum against RIG-I protein of Epinephelus coioides, which could be a useful reagent for further study of Grouper immune response and signal transduction upon virus infection. Advisors/Committee Members: Tsung-Chou Chang (chair), Jiin-Tsuey Cheng (committee member), Chung-Da Yang (chair).

Subjects/Keywords: Epinephelus coioides; RIG-I; poly(I:C); antiserum; fusion protein

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Chang, S. (2013). Production and characterization of polyclonal antibody against Epinephelus coioides retinoic acid inducible gene-I. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0327113-142030

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Chang, Shuo-Fu. “Production and characterization of polyclonal antibody against Epinephelus coioides retinoic acid inducible gene-I.” 2013. Thesis, NSYSU. Accessed January 16, 2021. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0327113-142030.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Chang, Shuo-Fu. “Production and characterization of polyclonal antibody against Epinephelus coioides retinoic acid inducible gene-I.” 2013. Web. 16 Jan 2021.

Vancouver:

Chang S. Production and characterization of polyclonal antibody against Epinephelus coioides retinoic acid inducible gene-I. [Internet] [Thesis]. NSYSU; 2013. [cited 2021 Jan 16]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0327113-142030.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Chang S. Production and characterization of polyclonal antibody against Epinephelus coioides retinoic acid inducible gene-I. [Thesis]. NSYSU; 2013. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0327113-142030

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

11. Reid, Dariya. Curvature-directed Crystallization of Polymer Dielectrics in Nanopores.

Degree: 2013, Texas Digital Library

URL: http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66723

► The formation of isotactic poly(propylene) (iPP) and polycarbonate (PC) nanowires of tunable diameter was demonstrated by melt-wetting the polymer into nanoporous anodic alumina. The crystallization… (more)

Subjects/Keywords: isotactic poly(propylene)

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APA (6^th Edition):

Reid, D. (2013). Curvature-directed Crystallization of Polymer Dielectrics in Nanopores. (Thesis). Texas Digital Library. Retrieved from http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66723

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Reid, Dariya. “Curvature-directed Crystallization of Polymer Dielectrics in Nanopores.” 2013. Thesis, Texas Digital Library. Accessed January 16, 2021. http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66723.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Reid, Dariya. “Curvature-directed Crystallization of Polymer Dielectrics in Nanopores.” 2013. Web. 16 Jan 2021.

Vancouver:

Reid D. Curvature-directed Crystallization of Polymer Dielectrics in Nanopores. [Internet] [Thesis]. Texas Digital Library; 2013. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66723.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Reid D. Curvature-directed Crystallization of Polymer Dielectrics in Nanopores. [Thesis]. Texas Digital Library; 2013. Available from: http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66723

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

12. Souza, Rachel. Integrated cue-reactivity paradigm to assess selective attention to simultaneous alcohol and smoking cues: A pilot study (CRET).

Degree: Behavioral and Social Sciences Department, 2018, Brown University

URL: https://repository.library.brown.edu/studio/item/bdr:792826/

► Alcohol and cigarettes are commonly used together and >80% of individuals with an alcohol use disorder (AUD) are also smokers. Attention bias is the tendency… (more)

▼ Alcohol and cigarettes are commonly used together and >80% of individuals with an alcohol use disorder (AUD) are also smokers. Attention bias is the tendency of our perception to be affected by our recurring thoughts and represents a key area of research in addiction psychiatry. However, current paradigms developed to assess attentional biases are limited to individual cues investigating the general process rather than investigating how this process might be manifested in terms of selective attention. It has been previously shown that in smokers with AUD, there exists a potentiation of attentional processing towards specific related cues, which in turn, escalates craving of the preferred substance. The primary aim of this study was to develop a novel paradigm that integrated a cue-reactivity (CR) session (bar laboratory) with an eye-tracking (ET) session (virtual laboratory) to directly measure selective behavioral response and selective visual attention. In each session, participants’ interaction with alcohol and cigarette was determined in order to investigate which substance was associated with an attentional bias. To provide an additional tool to measure and capture craving from psychological and visual perspectives, we also explored possible correlations between time spent with alcohol or cigarette with selective substance craving. This was a pilot human laboratory study (n = 32) with moderate to heavy drinking smokers who completed both a CR session and an ET session using their preferred alcoholic drink and cigarette brand in order to link behavior, attention and cravings in dual users. In the CR, when we compare the time spent interacting with either alcohol or cigarette, there was a difference between alcohol (p<0.001) and cigarette (p<0.01) when compared to water, but there was no difference between the two substances (p’s>0.05). In the ET session, when we compare the time spent interacting with either alcohol or cigarette, there was a difference between cigarette and alcohol (p’s<0.001) compared to water, but there was no difference between the two substances (p’s>0.05). In the integration of the CR session with the ET session, time spent interacting with alcohol in the CR session is correlated to total time fixating on alcohol during the ET session, p<0.05). However, the time spent interacting with the cigarette in the CR session trends towards correlation with time fixating on the cigarette during the ET session (p=0.06). In the analysis of craving, the time spent with alcohol during CR is correlated both with cravings for alcohol and cigarettes (p’s<0.05). Finally, when grouping participants by self-reported preferred substance, alcohol cravings were higher both for individuals that preferred alcohol (p <0.05) and for individuals that preferred cigarettes (p<0.05). With results indicating that the integrated paradigm is a novel and useful measure to relate behavior and attention in dual users, a larger study can be developed to further elucidate the drivers of behavior and attention as well as cravings… Advisors/Committee Members: Haass-Koffler, Carolina (Advisor), Aston, Elizabeth (Reader).

Subjects/Keywords: Poly substance use

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Souza, R. (2018). Integrated cue-reactivity paradigm to assess selective attention to simultaneous alcohol and smoking cues: A pilot study (CRET). (Thesis). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:792826/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Souza, Rachel. “Integrated cue-reactivity paradigm to assess selective attention to simultaneous alcohol and smoking cues: A pilot study (CRET).” 2018. Thesis, Brown University. Accessed January 16, 2021. https://repository.library.brown.edu/studio/item/bdr:792826/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Souza, Rachel. “Integrated cue-reactivity paradigm to assess selective attention to simultaneous alcohol and smoking cues: A pilot study (CRET).” 2018. Web. 16 Jan 2021.

Vancouver:

Souza R. Integrated cue-reactivity paradigm to assess selective attention to simultaneous alcohol and smoking cues: A pilot study (CRET). [Internet] [Thesis]. Brown University; 2018. [cited 2021 Jan 16]. Available from: https://repository.library.brown.edu/studio/item/bdr:792826/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Souza R. Integrated cue-reactivity paradigm to assess selective attention to simultaneous alcohol and smoking cues: A pilot study (CRET). [Thesis]. Brown University; 2018. Available from: https://repository.library.brown.edu/studio/item/bdr:792826/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Princeton University

13. Gaska, Jenna Marie. MOLECULAR DETERMINANTS OF HEPATITIS C VIRUS SPECIES TROPISM .

Degree: PhD, 2019, Princeton University

URL: http://arks.princeton.edu/ark:/88435/dsp01qn59q692m

► Communicable diseases, including infectious disease, remained the second highest contributor to the total number of disability adjusted life-years (DALYs) lost in 2017 (more than 17%… (more)

▼ Communicable diseases, including infectious disease, remained the second highest contributor to the total number of disability adjusted life-years (DALYs) lost in 2017 (more than 17% of the 2.5 billion DALYs) (1). The pathogens responsible for these diseases are a diverse array of viruses, bacteria and parasites, each with varying tropism, i.e. the propensity of a given pathogen to infect a particular cell type, tissue and/or species. At the level of species tropism, some pathogens are more promiscuous than others, infecting a broad range of vertebrates and invertebrates (e.g. the bacterium Salmonella enterica) while on the opposite end of the spectrum are pathogens with highly restricted tropism limited to only humans or humans and select non-human primate (NHP) species (e.g. hepatitis C virus, HCV). It is the latter category of pathogens that are most problematic for researchers as their very nature hinders study in traditional small animal models, such as mice. Thus, to facilitate such work, it is crucial to identify the determinants of tropism, which at the molecular level can be due to: (i) necessary factors missing or the ortholog of such a factor being incompatible in a given species, such as receptors for a specific virus; (ii) the presence of dominant restriction factors that block steps of the pathogen’s life cycle, such as its replication within host cells; (iii) the varying abilities of a pathogen to evade and/or disrupt the immune response of a given host. The following dissertation describes telling examples of these determinants, specifically for RNA viruses infecting humans, and how knowledge of such factors is important in generating improved research models as well as in understanding emergent and re-emergent pathogens. This work provides novel insights concerning the impact of cyclophilin A on HCV host tropism and the conservation of innate immune responses observed across diverse NHP species, with implications for the development of a small, immunocompetent animal model for HCV and related pathogens. Advisors/Committee Members: Ploss, Alexander (advisor).

Subjects/Keywords: cell-intrinsic immunity; cyclophilin A; hepatitis C virus; non-human primates; poly(I:C); RNA sequencing

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Gaska, J. M. (2019). MOLECULAR DETERMINANTS OF HEPATITIS C VIRUS SPECIES TROPISM . (Doctoral Dissertation). Princeton University. Retrieved from http://arks.princeton.edu/ark:/88435/dsp01qn59q692m

Chicago Manual of Style (16^th Edition):

Gaska, Jenna Marie. “MOLECULAR DETERMINANTS OF HEPATITIS C VIRUS SPECIES TROPISM .” 2019. Doctoral Dissertation, Princeton University. Accessed January 16, 2021. http://arks.princeton.edu/ark:/88435/dsp01qn59q692m.

MLA Handbook (7^th Edition):

Gaska, Jenna Marie. “MOLECULAR DETERMINANTS OF HEPATITIS C VIRUS SPECIES TROPISM .” 2019. Web. 16 Jan 2021.

Vancouver:

Gaska JM. MOLECULAR DETERMINANTS OF HEPATITIS C VIRUS SPECIES TROPISM . [Internet] [Doctoral dissertation]. Princeton University; 2019. [cited 2021 Jan 16]. Available from: http://arks.princeton.edu/ark:/88435/dsp01qn59q692m.

Council of Science Editors:

Gaska JM. MOLECULAR DETERMINANTS OF HEPATITIS C VIRUS SPECIES TROPISM . [Doctoral Dissertation]. Princeton University; 2019. Available from: http://arks.princeton.edu/ark:/88435/dsp01qn59q692m

University of Sydney

14. Bae, Dong-Hun. The Effects of Iron Levels on the Interaction between Polyamine Metabolism and Iron Metabolism in Neoplastic Cells .

Degree: 2018, University of Sydney

URL: http://hdl.handle.net/2123/18081

► Iron is a crucial element that is associated with many metabolic pathways important for life sustaining processes. Polyamines are small positively charged polycations involved in… (more)

▼ Iron is a crucial element that is associated with many metabolic pathways important for life sustaining processes. Polyamines are small positively charged polycations involved in various physiological functions. Both iron and polyamines levels are known to be high in cancer cells which suggests a possible unexplored link between the two metabolic pathways. For the first time, we demonstrate that iron-depletion robustly regulates the expression of 13 polyamine pathway proteins. Iron-depletion also decreased polyamine and S-adenosylmethionine levels (required for spermidine/spermine biosynthesis) and decreased 3H-spermidine uptake in accordance with expression of the polyamine importer, SLC22A16. The “reprogramming” of polyamine metabolism by iron-depletion showed dependence on the proto-oncogene, c-Myc, and tumour suppressor, p53 expression. Furthermore, the ability of iron chelators to inhibit proliferation can be rescued by polyamine supplementation. Collectively, these data demonstrate that iron and polyamine metabolism are closely linked at multiple levels. Moreover, we have identified that the mRNA and protein expression of the iron-containing enzyme, aci-reductone dioxygenase 1 (ADI1), was regulated by iron levels. Cellular iron depletion or deficient ADI1 metalation by the iron chaperone, PCBP1, promotes the proteasomal degradation of ADI1. Collectively, this demonstrates that cellular iron regulates ADI1 stability, a key enzyme involved in methionine salvage, polyamine biosynthesis and proliferation. In addition to regulating ADI1, poly(rC)-binding proteins (PCBPs) have been reported to function as iron-binding chaperones that deliver iron to ferritin. We observed that PCBP2 enhances, while PCBP1 inhibits ferritin 59Fe-loading and ferritin protein expression. Our results suggest that the regulation of ferritin iron-loading by PCBPs may involve a combination of translational regulation and/or iron chaperone activity. Overall this study has demonstrated for the first time the direct interaction between iron metabolism and polyamine metabolism, which is important in understanding how cancer cells can survive adverse environments.

Subjects/Keywords: iron; polyamines; acireductone dioxygenase (ADI1); poly-r(C)-binding proteins (PCBPs); ferritin

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APA (6^th Edition):

Bae, D. (2018). The Effects of Iron Levels on the Interaction between Polyamine Metabolism and Iron Metabolism in Neoplastic Cells . (Thesis). University of Sydney. Retrieved from http://hdl.handle.net/2123/18081

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Bae, Dong-Hun. “The Effects of Iron Levels on the Interaction between Polyamine Metabolism and Iron Metabolism in Neoplastic Cells .” 2018. Thesis, University of Sydney. Accessed January 16, 2021. http://hdl.handle.net/2123/18081.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Bae, Dong-Hun. “The Effects of Iron Levels on the Interaction between Polyamine Metabolism and Iron Metabolism in Neoplastic Cells .” 2018. Web. 16 Jan 2021.

Vancouver:

Bae D. The Effects of Iron Levels on the Interaction between Polyamine Metabolism and Iron Metabolism in Neoplastic Cells . [Internet] [Thesis]. University of Sydney; 2018. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/2123/18081.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bae D. The Effects of Iron Levels on the Interaction between Polyamine Metabolism and Iron Metabolism in Neoplastic Cells . [Thesis]. University of Sydney; 2018. Available from: http://hdl.handle.net/2123/18081

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Georgia

15. Agrawal, Ankit. Novel pathways for transfer RNA processing and maturation in Escherichia coli.

Degree: 2014, University of Georgia

URL: http://hdl.handle.net/10724/30819

► Post-transcriptional processing of all tRNA primary transcripts constitutes an important cellular activity, thought to play a role in regulation of protein synthesis and overall cell… (more)

Subjects/Keywords: tRNA; RNase P; RNase E; valine; lysine; polyadenylation; PAP I; poly(A) polymerase I; Escherichia coli; E. coli

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APA (6^th Edition):

Agrawal, A. (2014). Novel pathways for transfer RNA processing and maturation in Escherichia coli. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/30819

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Agrawal, Ankit. “Novel pathways for transfer RNA processing and maturation in Escherichia coli.” 2014. Thesis, University of Georgia. Accessed January 16, 2021. http://hdl.handle.net/10724/30819.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Agrawal, Ankit. “Novel pathways for transfer RNA processing and maturation in Escherichia coli.” 2014. Web. 16 Jan 2021.

Vancouver:

Agrawal A. Novel pathways for transfer RNA processing and maturation in Escherichia coli. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/10724/30819.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Agrawal A. Novel pathways for transfer RNA processing and maturation in Escherichia coli. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/30819

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Texas Medical Center

16. Zhou, Zhicheng, Mr. CHARACTERIZATION OF THE ROLES OF CARMA3 AND BCL10 IN VIRUS-TRIGGERED RIG-I/MAVS SIGNALING PATHWAY.

Degree: PhD, 2015, Texas Medical Center

URL: https://digitalcommons.library.tmc.edu/utgsbs_dissertations/546

► After RNA virus infection, the innate immunity utilizes RIG-I family of receptors in the cytoplasm to initiate the production of type-I IFNs and proinflammatory… (more)

Subjects/Keywords: CARMA3; BCL10; RIG-I/MAVS signaling pathway; Type I interferon; Influenza virus; VSV; Poly(I:C); DsRNA;

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APA (6^th Edition):

Zhou, Zhicheng, M. (2015). CHARACTERIZATION OF THE ROLES OF CARMA3 AND BCL10 IN VIRUS-TRIGGERED RIG-I/MAVS SIGNALING PATHWAY. (Doctoral Dissertation). Texas Medical Center. Retrieved from https://digitalcommons.library.tmc.edu/utgsbs_dissertations/546

Chicago Manual of Style (16^th Edition):

Zhou, Zhicheng, Mr. “CHARACTERIZATION OF THE ROLES OF CARMA3 AND BCL10 IN VIRUS-TRIGGERED RIG-I/MAVS SIGNALING PATHWAY.” 2015. Doctoral Dissertation, Texas Medical Center. Accessed January 16, 2021. https://digitalcommons.library.tmc.edu/utgsbs_dissertations/546.

MLA Handbook (7^th Edition):

Zhou, Zhicheng, Mr. “CHARACTERIZATION OF THE ROLES OF CARMA3 AND BCL10 IN VIRUS-TRIGGERED RIG-I/MAVS SIGNALING PATHWAY.” 2015. Web. 16 Jan 2021.

Vancouver:

Zhou, Zhicheng M. CHARACTERIZATION OF THE ROLES OF CARMA3 AND BCL10 IN VIRUS-TRIGGERED RIG-I/MAVS SIGNALING PATHWAY. [Internet] [Doctoral dissertation]. Texas Medical Center; 2015. [cited 2021 Jan 16]. Available from: https://digitalcommons.library.tmc.edu/utgsbs_dissertations/546.

Council of Science Editors:

Zhou, Zhicheng M. CHARACTERIZATION OF THE ROLES OF CARMA3 AND BCL10 IN VIRUS-TRIGGERED RIG-I/MAVS SIGNALING PATHWAY. [Doctoral Dissertation]. Texas Medical Center; 2015. Available from: https://digitalcommons.library.tmc.edu/utgsbs_dissertations/546

17. Rayeroux, David. Polymérisation radicalaire contrôlée par transfert d'iode en mode inverse (RITP) : Synthèse de copolymères amphiphiles : Reverse Iodine Transfer radical Polymerisation (RITP) : Synthesis of amphiphilic copolymers.

Degree: Docteur es, Chimie et Physicochimie des matériaux, 2012, Montpellier, Ecole nationale supérieure de chimie

URL: http://www.theses.fr/2012ENCM0025

►

Ce travail de thèse décrit la synthèse de copolymères diblocs amphiphiles par polymérisation radicalaire contrôlée par transfert d'iode en mode inverse (RITP). Dans un premier… (more)

▼

Ce travail de thèse décrit la synthèse de copolymères diblocs amphiphiles par polymérisation radicalaire contrôlée par transfert d'iode en mode inverse (RITP). Dans un premier temps, des homopolymères à base de monomères activés (styrène, acrylate de méthyle, méthacrylate de méthyle), non activés (acétate de vinyle) et fonctionnels (chlorométhylstyrène, acrylate de tert-butyle), ont été synthétisés par RITP. Des aspects tels que le contrôle des masses molaires ainsi que la fonctionnalité en iode du bout de chaîne ont été examinés. Afin de démontrer la compatibilité de la RITP avec d'autres techniques de polymérisation contrôlée/vivante (non radicalaires), le copolymère amphiphile non-ionique poly(styrène)-b-poly(2-méthyl-2-oxazoline) (PS-b-P(MOx)) a été élaboré par la voie toute iode en procédé « one-pot » en combinant de manière consécutive la RITP du styrène avec la polymérisation cationique par ouverture de cycle (CROP) de la 2-méthyl-2-oxazoline. Par ailleurs, des copolymères cationiques poly(styrène)-b-poly(chlorométhylstyrène) quaternisé avec la triéthylamine (PS-b-PCMS+) et anioniques poly(styrène)-b-poly(acide acrylique) (PS-b-PAA-) ont été synthétisés par RITP du styrène suivie de l'ITP du bloc hydrophile. Tous ces copolymères amphiphiles ont été obtenus à partir de polystyrène iodé (PS-I) de faibles masses molaires, allant de 1000 à 3000 g.mol-1, jouant le rôle de macro-amorceurs (CROP) ou de macro-agents de transfert (ITP). L'étude de l'auto-organisation en phase aqueuse de ces copolymères amphiphiles a révélé la formation de micelles pour des concentrations supérieures à la concentration d'agrégation critique (CAC) dont la valeur a été déterminée par diffusion dynamique de la lumière (DDL) et spectroscopie de fluorescence. Enfin, des résultats très prometteurs ont été obtenus dans l'utilisation d'un copolymère cationique amphiphile PS-b-PCMS+ comme agents structurants de matériaux siliciques mésoporeux nanostructurés élaborés par procédé sol-gel en milieu basique. La synthèse de ces copolymères amphiphiles ainsi que leur caractérisation physico-chimique ont mis en exergue que la RITP permet de couvrir la synthèse de différentes catégories de copolymères amphiphiles, tout en étant une technique simple à mettre en œuvre, peu couteuse et robuste.

This manuscript describes the synthesis of amphiphilic diblock copolymers by reverse iodine transfer polymerization (RITP). Firstly, homopolymers derived from activated (styrene, methyl acrylate, methyl methacrylate), non-activated (vinyl acetate) and functional monomers (chloromethylstyrene, tert-butyl acrylate) synthesized by RITP, were studied. Aspects including molecular weight control as well as iodine chain-end functionality were investigated. In order to highlight the compatibility of RITP with other living/controlled (non-radical) polymerization techniques, a poly(styrene)-b-poly(2-methyl-2-oxazoline) (PS-b-P(MOx)) non-ionic copolymer was conceived through an ‘all-iodine', ‘one-pot' process by combining successively RITP of styrene with cationic…

Advisors/Committee Members: Lacroix-Desmazes, Patrick (thesis director).

Subjects/Keywords: Copolymères amphiphiles; Ritp; Crop; Poly(acide acrylique); Poly(chlorométhylstyrène); Poly(2-méthyl-2-oxazoline); Amphiphilic copolymers; Ritp; Crop; Poly(acrylic acid); Poly(chloromethylstyrene); Poly(2-methyl-2-oxazoline)

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Rayeroux, D. (2012). Polymérisation radicalaire contrôlée par transfert d'iode en mode inverse (RITP) : Synthèse de copolymères amphiphiles : Reverse Iodine Transfer radical Polymerisation (RITP) : Synthesis of amphiphilic copolymers. (Doctoral Dissertation). Montpellier, Ecole nationale supérieure de chimie. Retrieved from http://www.theses.fr/2012ENCM0025

Chicago Manual of Style (16^th Edition):

Rayeroux, David. “Polymérisation radicalaire contrôlée par transfert d'iode en mode inverse (RITP) : Synthèse de copolymères amphiphiles : Reverse Iodine Transfer radical Polymerisation (RITP) : Synthesis of amphiphilic copolymers.” 2012. Doctoral Dissertation, Montpellier, Ecole nationale supérieure de chimie. Accessed January 16, 2021. http://www.theses.fr/2012ENCM0025.

MLA Handbook (7^th Edition):

Rayeroux, David. “Polymérisation radicalaire contrôlée par transfert d'iode en mode inverse (RITP) : Synthèse de copolymères amphiphiles : Reverse Iodine Transfer radical Polymerisation (RITP) : Synthesis of amphiphilic copolymers.” 2012. Web. 16 Jan 2021.

Vancouver:

Rayeroux D. Polymérisation radicalaire contrôlée par transfert d'iode en mode inverse (RITP) : Synthèse de copolymères amphiphiles : Reverse Iodine Transfer radical Polymerisation (RITP) : Synthesis of amphiphilic copolymers. [Internet] [Doctoral dissertation]. Montpellier, Ecole nationale supérieure de chimie; 2012. [cited 2021 Jan 16]. Available from: http://www.theses.fr/2012ENCM0025.

Council of Science Editors:

Rayeroux D. Polymérisation radicalaire contrôlée par transfert d'iode en mode inverse (RITP) : Synthèse de copolymères amphiphiles : Reverse Iodine Transfer radical Polymerisation (RITP) : Synthesis of amphiphilic copolymers. [Doctoral Dissertation]. Montpellier, Ecole nationale supérieure de chimie; 2012. Available from: http://www.theses.fr/2012ENCM0025

18. Heffernan, Michael John. Biodegradable polymeric delivery systems for protein subunit vaccines.

Degree: PhD, Biomedical Engineering, 2008, Georgia Tech

URL: http://hdl.handle.net/1853/24787

► The prevention and treatment of cancer and infectious diseases requires vaccines that can mediate cytotoxic T lymphocyte-based immunity. A promising strategy is protein subunit vaccines… (more)

▼ The prevention and treatment of cancer and infectious diseases requires vaccines that can mediate cytotoxic T lymphocyte-based immunity. A promising strategy is protein subunit vaccines composed of purified protein antigens and immunostimulatory adjuvants, such as Toll-like receptor (TLR) agonists. In this research, we developed two new biodegradable polymeric delivery vehicles for protein antigens and TLR agonists, as model vaccine delivery systems. This work was guided by the central hypothesis that an effective vaccine delivery system would have stimulus-responsive degradation and release, biodegradability into excretable non-acidic degradation products, and the ability to incorporate various TLR-inducing adjuvants. The first vaccine delivery system is a cross-linked polyion complex micelle which efficiently encapsulates proteins, DNA, and RNA. The micelle-based delivery system consists of a block copolymer of poly(ethylene glycol) (PEG) and poly(L-lysine), cross-linked by dithiopyridyl side groups to provide transport stability and intracellular release. The second delivery system consists of solid biodegradable microparticles encapsulating proteins, nucleic acids, and hydrophobic compounds. The microparticles are composed of pH-sensitive polyketals, which are a new family of hydrophobic, linear polymers containing backbone ketal linkages. Polyketals are synthesized via a new polymerization method based on the acetal exchange reaction and degrade into non-acidic, excretable degradation products. In addition, the technique of hydrophobic ion pairing was utilized to enhance the encapsulation of ovalbumin, DNA, and RNA in polyketal microparticles via a single emulsion method. Using in vitro and in vivo immunological models, we demonstrated that the micelle- and polyketal-based vaccine delivery systems enhanced the cross-priming of cytotoxic T lymphocytes. The model vaccines were composed of ovalbumin antigen and various TLR-inducing adjuvants including CpG-DNA, monophosphoryl lipid A, and dsRNA. The results demonstrate that the cross-linked micelles and polyketal microparticles have considerable potential as delivery systems for protein-based vaccines. Advisors/Committee Members: Dr. Niren Murthy (Committee Chair), Dr. Carson Meredith (Committee Member), Dr. Julia Babensee (Committee Member), Dr. Mark Prausnitz (Committee Member), Dr. Ravi Bellamkonda (Committee Member).

Subjects/Keywords: Vaccine delivery; Drug delivery; Microencapsulation; Nanospheres; Microspheres; Nanoparticles; Polyacetal; PH-responsive; TLR ligands; Poly(I)-poly(C); Acid-degradable; Vaccines; Polymeric drug delivery systems; Biodegradable plastics

…micelle self-assembly. 20 Figure 2.2. PEG-poly(lysine-dithiopyridyl) (PEG-PLTP… …antigen and Poly(I:C). 25 Figure 2.4. Agarose gel of cross-linked copolymer micelles… …with ovalbumin, CpG DNA, and poly(I:C). 27 Figure 2.5. SDS-PAGE (4-20%)… …poly(I:C) to CTAB and ovalbumin to CTAB. 39 Figure 3.4. Synthesis of the polyketal… …poly(1,4,-phenylene-acetone dimethylene ketal)(PPADK), via the acetal…

10 more images…

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APA (6^th Edition):

Heffernan, M. J. (2008). Biodegradable polymeric delivery systems for protein subunit vaccines. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/24787

Chicago Manual of Style (16^th Edition):

Heffernan, Michael John. “Biodegradable polymeric delivery systems for protein subunit vaccines.” 2008. Doctoral Dissertation, Georgia Tech. Accessed January 16, 2021. http://hdl.handle.net/1853/24787.

MLA Handbook (7^th Edition):

Heffernan, Michael John. “Biodegradable polymeric delivery systems for protein subunit vaccines.” 2008. Web. 16 Jan 2021.

Vancouver:

Heffernan MJ. Biodegradable polymeric delivery systems for protein subunit vaccines. [Internet] [Doctoral dissertation]. Georgia Tech; 2008. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1853/24787.

Council of Science Editors:

Heffernan MJ. Biodegradable polymeric delivery systems for protein subunit vaccines. [Doctoral Dissertation]. Georgia Tech; 2008. Available from: http://hdl.handle.net/1853/24787

19. Brunelle, Alexander Robert. Moldless Hydrogel Scaffold for 3D Cell Culture.

Degree: Bioengineering, 2017, University of California – Riverside

URL: http://www.escholarship.org/uc/item/4qz7b68w

► Many fabrication methods for scaffolds made with biodegradable polymers and hydrogels have shown promise for tissue engineering applications. Both possess their own benefits and disadvantages.… (more)

Subjects/Keywords: Biomedical engineering; differentiation; electrospun; poly caprolactone; poly (ethylene glycol)- poly (N-isopropylacrylamide); scaffold; thermosensitive hydrogel

10 more images…

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APA (6^th Edition):

Brunelle, A. R. (2017). Moldless Hydrogel Scaffold for 3D Cell Culture. (Thesis). University of California – Riverside. Retrieved from http://www.escholarship.org/uc/item/4qz7b68w

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Brunelle, Alexander Robert. “Moldless Hydrogel Scaffold for 3D Cell Culture.” 2017. Thesis, University of California – Riverside. Accessed January 16, 2021. http://www.escholarship.org/uc/item/4qz7b68w.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Brunelle, Alexander Robert. “Moldless Hydrogel Scaffold for 3D Cell Culture.” 2017. Web. 16 Jan 2021.

Vancouver:

Brunelle AR. Moldless Hydrogel Scaffold for 3D Cell Culture. [Internet] [Thesis]. University of California – Riverside; 2017. [cited 2021 Jan 16]. Available from: http://www.escholarship.org/uc/item/4qz7b68w.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Brunelle AR. Moldless Hydrogel Scaffold for 3D Cell Culture. [Thesis]. University of California – Riverside; 2017. Available from: http://www.escholarship.org/uc/item/4qz7b68w

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

20. Gomes, Catarina Pereira. Surfactant-free emulsion polymerization by “Grafting from” polyvinylamine stabilizer.

Degree: 2014, Instituto Politécnico de Bragança

URL: https://www.rcaap.pt/detail.jsp?id=oai:bibliotecadigital.ipb.pt:10198/11514

► Emulsion polymerization technique is one of the most common techniques employed in industry to synthesize a wide range of polymers due to its versatility, the… (more)

▼ Emulsion polymerization technique is one of the most common techniques employed in industry to synthesize a wide range of polymers due to its versatility, the possibility to control the properties of the final product and because it is an environmentally friendly technique. Nevertheless, large amounts of surfactant are usually required to stabilize the system which can have deleterious effects on water resistance and on the mechanical properties of the polymer. Among the different techniques employed to circumvent this problem, recently, graft copolymerization of a monomer from water-soluble polymers containing amino groups has been employed to synthesize polymer particles with amphiphilic core-shell nanostructures. Applications of these particles include controlled release drugs, water-borne coatings and diagnostic testing. In this project, water-soluble poly (N-vinylformamide) (PNVF) of different molecular weights was synthesized and characterized. Subsequently, the basic hydrolysis of these polymers was accomplished to obtain poly (vinyl amine) (PVAm) in an easy and controlled way. The synthesized poly (vinyl amines) were then employed as stabilizers in the surfactant-free emulsion polymerization of methyl methacrylate (MMA). The MMA monomer polymerizes via two different ways, grafting from polyvinylamine and homopolymerization, leading to a core-shell type particles with polyvinylamine-based shells. The effect of different variables such as initiator type and concentration, the pH of the reaction and the molecular weight of PVAm’s on the conversion, grafting efficiency and morphology of the polymer particles were investigated. Throughout all the work, an extensive characterization of the polymers obtained in each step was performed in order to clarify possible mechanisms involved in this polymerization process. For the characterization of the polymeric particles obtained during this work were used some characterization techniques such as AF4, NMR, DLS, TEM, SEC/GPC and FT-IR. Advisors/Committee Members: Dias, Rolando, Leiza, Jose Ramon.

Subjects/Keywords: Surfactant free emulsion polymerization; Poly (N-vinylformamide); Poly (vinyl amine); Poly (methylmetacrylate); Graft copolymerization

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APA (6^th Edition):

Gomes, C. P. (2014). Surfactant-free emulsion polymerization by “Grafting from” polyvinylamine stabilizer. (Thesis). Instituto Politécnico de Bragança. Retrieved from https://www.rcaap.pt/detail.jsp?id=oai:bibliotecadigital.ipb.pt:10198/11514

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Gomes, Catarina Pereira. “Surfactant-free emulsion polymerization by “Grafting from” polyvinylamine stabilizer.” 2014. Thesis, Instituto Politécnico de Bragança. Accessed January 16, 2021. https://www.rcaap.pt/detail.jsp?id=oai:bibliotecadigital.ipb.pt:10198/11514.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Gomes, Catarina Pereira. “Surfactant-free emulsion polymerization by “Grafting from” polyvinylamine stabilizer.” 2014. Web. 16 Jan 2021.

Vancouver:

Gomes CP. Surfactant-free emulsion polymerization by “Grafting from” polyvinylamine stabilizer. [Internet] [Thesis]. Instituto Politécnico de Bragança; 2014. [cited 2021 Jan 16]. Available from: https://www.rcaap.pt/detail.jsp?id=oai:bibliotecadigital.ipb.pt:10198/11514.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Gomes CP. Surfactant-free emulsion polymerization by “Grafting from” polyvinylamine stabilizer. [Thesis]. Instituto Politécnico de Bragança; 2014. Available from: https://www.rcaap.pt/detail.jsp?id=oai:bibliotecadigital.ipb.pt:10198/11514

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade Nova

21. Mano, Maria Francisca Amaral Gomes Marques. Fiber functionalization for biomedical applications.

Degree: 2014, Universidade Nova

URL: http://www.rcaap.pt/detail.jsp?id=oai:run.unl.pt:10362/13890

► Deep-eutectic solvents (DES) are considered novel renewable and biodegradable solvents, with a cheap and easy synthesis, without waste production. Later it was discovered a new… (more)

▼ Deep-eutectic solvents (DES) are considered novel renewable and biodegradable solvents, with a cheap and easy synthesis, without waste production. Later it was discovered a new subclass of DES that even can be biocompatible, since their synthesis uses primary metabolites such as amino acids, organic acids and sugars, from organisms. This subclass was named natural deep-eutectic solvents (NADES). Due to their properties it was tried to study the interaction between these solvents and biopolymers, in order to produce functionalized fibers for biomedical applications. In this way, fibers were produced by using the electrospinning technique. However, it was first necessary to study some physical properties of NADES, as well as the influence of water in their properties. It has been concluded that the water has a high influence on NADES properties, which can be seen on the results obtained from the rheology and viscosity studies. The fluid dynamics had changed, as well as the viscosity. Afterwards, it was tested the viability of using a starch blend. First it was tested the dissolution of these biopolymers into NADES, in order to study the viability of their application in electrospinning. However the results obtained were not satisfactory, since the starch polymers studied did not presented any dissolution in any NADES, or even in organic solvents. In this way it was changed the approach, and it was used other biocompatible polymers. Poly(ethylene oxide), poly(vinyl alcohol) and gelatin were the others biopolymers tested for the electrospinning, with NADES. All polymers show good results, since it was possible to obtain fibers. However for gelatin it was used only eutectic mixtures, containing active pharmaceutical ingredients (API’s), instead of NADES. For this case it was used mandelic acid (antimicrobial properties), choline chloride, ibuprofen (anti-inflammatory properties) and menthol (analgesic properties). The polymers and the produced fibers were characterized by scanning electron microscope (SEM), Transmission electron microscopy (TEM) and Fourier transform infrared spectroscopy (FTIR). With the help of these techniques it was possible to conclude that it was possible to encapsulate NADES within the fibers. Rheology it was also study for poly(ethylene oxide) and poly(vinyl alcohol), in a way to understand the influence of polymer concentration, on the electrospinning technique. For the gelatin, among the characterization techniques, it was also performed cytotoxicity and drug release studies. The gelatin membranes did not show any toxicity for the cells, since their viability was maintained. Regarding the controlled release profile experiment no conclusion could be drawn from the experiments, due to the rapid and complete dissolution of the gelatin in the buffer solution. However it was possible to quantify the mixture of choline chloride with mandelic acid, allowing thus to complete, and confirm, the information already obtained for the others characterization technique. Advisors/Committee Members: Paiva, Alexandre, Borges, João Paulo.

Subjects/Keywords: Natural deep eutectic solvents; Biopolymers; Starch; Poly(caprolactone); Poly(ethylene oxide); Poly(vinyl alcohol)

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APA (6^th Edition):

Mano, M. F. A. G. M. (2014). Fiber functionalization for biomedical applications. (Thesis). Universidade Nova. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:run.unl.pt:10362/13890

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Mano, Maria Francisca Amaral Gomes Marques. “Fiber functionalization for biomedical applications.” 2014. Thesis, Universidade Nova. Accessed January 16, 2021. http://www.rcaap.pt/detail.jsp?id=oai:run.unl.pt:10362/13890.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Mano, Maria Francisca Amaral Gomes Marques. “Fiber functionalization for biomedical applications.” 2014. Web. 16 Jan 2021.

Vancouver:

Mano MFAGM. Fiber functionalization for biomedical applications. [Internet] [Thesis]. Universidade Nova; 2014. [cited 2021 Jan 16]. Available from: http://www.rcaap.pt/detail.jsp?id=oai:run.unl.pt:10362/13890.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Mano MFAGM. Fiber functionalization for biomedical applications. [Thesis]. Universidade Nova; 2014. Available from: http://www.rcaap.pt/detail.jsp?id=oai:run.unl.pt:10362/13890

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

NSYSU

22. Weng, Chi-Feng. Electrical Properties and Reliability of Poly-Si TFTs for System On Panel Application.

Degree: PhD, Physics, 2009, NSYSU

URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0623109-111336

► English Abstract In this thesis, we investigate the electrical properties and reliabilities of poly-Si TFTs for system on panel application. Roughly, we divide the thesis… (more)

▼ English Abstract In this thesis, we investigate the electrical properties and reliabilities of poly-Si TFTs for system on panel application. Roughly, we divide the thesis into two parts, n-type and p-type TFTs respectively. In n-type TFT, we mainly study degradation characteristics of TFTs under dynamic stress. On the other hand, we focus on special negative bias temperature instability (NBTI) degradation for p-type poly-Si TFTs. Because grain boundary in poly-Si film and serious self-heating effect due to glass substrate, which has a poor thermal conductivity, the electrical properties and reliabilities of poly-Si TFTs become more complicated, compare with metal-oxide-semiconductor field effect transistor (MOSFET). Therefore, in the thesis, we found some strange phenomena never observed in a-Si TFT and MOSFET. In chapter 3, the degradation mechanism of n-channel poly-silicon thin film transistor (poly-Si TFT) has been investigated at room temperature under dynamic voltage stress, which simulate under high frequency operation as driving devices. The ON-current of TFT is degraded to as low as 0.3 times of the initial value after 1000 second stress. On the other hand, both the sub-threshold swing and threshold voltage kept well during the AC stress. The current crowding effect was rapidly increased with increasing of stress duration. However, comparing the initial and degraded characteristics at rising temperature, namely, 150◦C, the ON-current of TFT only decrease to 75 percent of the initial value after 1000 second AC stress. It depicts that creation of effective trap density in tail-states of poly-Si film is responsible for the electrical degradation of poly-Si TFT. At high temperature, electron has enough energy to pass the energy barrier created by ac stress and the degradation is less obvious. In chapter 4, the degradation mechanism of n-channel poly-silicon thin film transistor (poly-Si TFT) has been investigated under dynamic voltage stress, which simulate under low frequency operation as pixel switches. Surprisingly, two totally different degradations of TFTs were observed after dynamic stress. Firstly field-effect mobility and driving current increased during early stress. However, a clear and rapid degradation of field-effect mobility occurred instead during later stress. Additionally, the threshold voltage of stressed TFTs strangely shifted to negative direction in later stress, which was never observed in early stress. Finally, we clarify the degradation mechanisms for early and later stress respectively by varied temperature experiments. In chapter 5, the characteristics of p-type poly-silicon thin film transistor (poly-Si TFT) with dynamic bias stress were investigated. The AC stress is operated with the constant drain voltage (15V) and the varying gate voltage (0V~-15V) to degrade the devices. There are some phenomena which cannot be completely explained by typical NBTI mechanism in the experiment. In addition to NBTI, we suggest that the self-heating effect might be involved, because the self-heating… Advisors/Committee Members: Ann-Kuo Chu (chair), Tzyy-Ming Cheng (chair), Ting-Chang Chang (committee member), Cheng-Tung Huang (chair), Ming-Kwei Lee (chair).

Subjects/Keywords: TFT; Si; Poly-Si; Reliability

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Weng, C. (2009). Electrical Properties and Reliability of Poly-Si TFTs for System On Panel Application. (Doctoral Dissertation). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0623109-111336

Chicago Manual of Style (16^th Edition):

Weng, Chi-Feng. “Electrical Properties and Reliability of Poly-Si TFTs for System On Panel Application.” 2009. Doctoral Dissertation, NSYSU. Accessed January 16, 2021. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0623109-111336.

MLA Handbook (7^th Edition):

Weng, Chi-Feng. “Electrical Properties and Reliability of Poly-Si TFTs for System On Panel Application.” 2009. Web. 16 Jan 2021.

Vancouver:

Weng C. Electrical Properties and Reliability of Poly-Si TFTs for System On Panel Application. [Internet] [Doctoral dissertation]. NSYSU; 2009. [cited 2021 Jan 16]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0623109-111336.

Council of Science Editors:

Weng C. Electrical Properties and Reliability of Poly-Si TFTs for System On Panel Application. [Doctoral Dissertation]. NSYSU; 2009. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0623109-111336

23. Mitani, Masahiro. Relationship between Electrical Characteristics and Crystallographic Properties in Pseudo-Single-Crystal Silicon Thin-Film Transistors Fabricated by Phase-Modulated Excimer Laser Annealing : 位相変調エキシマレーザーアニーリングで作製した擬似単結晶シリコン薄膜トランジスタの電気的特性と結晶学的特性の関係の研究; イソウヘンチョウエキシマレーザーアニーリングデサクセイシタギジタンケッショウシリコンハクマクトランジスタノデンキテキトクセイトケッショウガクテキトクセイノカンケイノケンキュウ.

Degree: 博士(工学), Nara Institute of Science and Technology / 奈良先端科学技術大学院大学

URL: http://hdl.handle.net/10061/9325

Subjects/Keywords: poly-Si

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APA (6^th Edition):

Mitani, M. (n.d.). Relationship between Electrical Characteristics and Crystallographic Properties in Pseudo-Single-Crystal Silicon Thin-Film Transistors Fabricated by Phase-Modulated Excimer Laser Annealing : 位相変調エキシマレーザーアニーリングで作製した擬似単結晶シリコン薄膜トランジスタの電気的特性と結晶学的特性の関係の研究; イソウヘンチョウエキシマレーザーアニーリングデサクセイシタギジタンケッショウシリコンハクマクトランジスタノデンキテキトクセイトケッショウガクテキトクセイノカンケイノケンキュウ. (Thesis). Nara Institute of Science and Technology / 奈良先端科学技術大学院大学. Retrieved from http://hdl.handle.net/10061/9325

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Mitani, Masahiro. “Relationship between Electrical Characteristics and Crystallographic Properties in Pseudo-Single-Crystal Silicon Thin-Film Transistors Fabricated by Phase-Modulated Excimer Laser Annealing : 位相変調エキシマレーザーアニーリングで作製した擬似単結晶シリコン薄膜トランジスタの電気的特性と結晶学的特性の関係の研究; イソウヘンチョウエキシマレーザーアニーリングデサクセイシタギジタンケッショウシリコンハクマクトランジスタノデンキテキトクセイトケッショウガクテキトクセイノカンケイノケンキュウ.” Thesis, Nara Institute of Science and Technology / 奈良先端科学技術大学院大学. Accessed January 16, 2021. http://hdl.handle.net/10061/9325.

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Mitani, Masahiro. “Relationship between Electrical Characteristics and Crystallographic Properties in Pseudo-Single-Crystal Silicon Thin-Film Transistors Fabricated by Phase-Modulated Excimer Laser Annealing : 位相変調エキシマレーザーアニーリングで作製した擬似単結晶シリコン薄膜トランジスタの電気的特性と結晶学的特性の関係の研究; イソウヘンチョウエキシマレーザーアニーリングデサクセイシタギジタンケッショウシリコンハクマクトランジスタノデンキテキトクセイトケッショウガクテキトクセイノカンケイノケンキュウ.” Web. 16 Jan 2021.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Vancouver:

Mitani M. Relationship between Electrical Characteristics and Crystallographic Properties in Pseudo-Single-Crystal Silicon Thin-Film Transistors Fabricated by Phase-Modulated Excimer Laser Annealing : 位相変調エキシマレーザーアニーリングで作製した擬似単結晶シリコン薄膜トランジスタの電気的特性と結晶学的特性の関係の研究; イソウヘンチョウエキシマレーザーアニーリングデサクセイシタギジタンケッショウシリコンハクマクトランジスタノデンキテキトクセイトケッショウガクテキトクセイノカンケイノケンキュウ. [Internet] [Thesis]. Nara Institute of Science and Technology / 奈良先端科学技術大学院大学; [cited 2021 Jan 16]. Available from: http://hdl.handle.net/10061/9325.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

Council of Science Editors:

Mitani M. Relationship between Electrical Characteristics and Crystallographic Properties in Pseudo-Single-Crystal Silicon Thin-Film Transistors Fabricated by Phase-Modulated Excimer Laser Annealing : 位相変調エキシマレーザーアニーリングで作製した擬似単結晶シリコン薄膜トランジスタの電気的特性と結晶学的特性の関係の研究; イソウヘンチョウエキシマレーザーアニーリングデサクセイシタギジタンケッショウシリコンハクマクトランジスタノデンキテキトクセイトケッショウガクテキトクセイノカンケイノケンキュウ. [Thesis]. Nara Institute of Science and Technology / 奈良先端科学技術大学院大学; Available from: http://hdl.handle.net/10061/9325

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

24. Guirous, Houria. Synthèse et caractérisation de la polycaprolactone.

Degree: 2011, Université M'Hamed Bougara Boumerdès

URL: http://dlibrary.univ-boumerdes.dz:8080/jspui/handle/123456789/479

►

71 p. ; ill. ; 30 cm

La polycaprolactone est l'un des polyesters aliphatiques la plus couramment utilisée pour des applications médicales grâce à sa… (more)

Subjects/Keywords: Polyesters; Poly (epsilon-caprolactone); Microencapsulation

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Guirous, H. (2011). Synthèse et caractérisation de la polycaprolactone. (Thesis). Université M'Hamed Bougara Boumerdès. Retrieved from http://dlibrary.univ-boumerdes.dz:8080/jspui/handle/123456789/479

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Guirous, Houria. “Synthèse et caractérisation de la polycaprolactone.” 2011. Thesis, Université M'Hamed Bougara Boumerdès. Accessed January 16, 2021. http://dlibrary.univ-boumerdes.dz:8080/jspui/handle/123456789/479.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Guirous, Houria. “Synthèse et caractérisation de la polycaprolactone.” 2011. Web. 16 Jan 2021.

Vancouver:

Guirous H. Synthèse et caractérisation de la polycaprolactone. [Internet] [Thesis]. Université M'Hamed Bougara Boumerdès; 2011. [cited 2021 Jan 16]. Available from: http://dlibrary.univ-boumerdes.dz:8080/jspui/handle/123456789/479.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Guirous H. Synthèse et caractérisation de la polycaprolactone. [Thesis]. Université M'Hamed Bougara Boumerdès; 2011. Available from: http://dlibrary.univ-boumerdes.dz:8080/jspui/handle/123456789/479

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Anna University

25. Mageswari S. Synthesis characterization of Acrylic and methacrylic polymers And their adhesive and Antibacterial properties;.

Degree: Synthesis characterization of Acrylic and methacrylic polymers And their adhesive and Antibacterial properties, 2015, Anna University

URL: http://shodhganga.inflibnet.ac.in/handle/10603/33539

►

Acrylic and methacrylic polymers are used extensively in academic newlineand industrial research These monomers are being used to synthesize a newlinenumber of polymers due to… (more)

Subjects/Keywords: Methacryloyl chloride; Poly acrylic acid

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APA (6^th Edition):

S, M. (2015). Synthesis characterization of Acrylic and methacrylic polymers And their adhesive and Antibacterial properties;. (Thesis). Anna University. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/33539

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

S, Mageswari. “Synthesis characterization of Acrylic and methacrylic polymers And their adhesive and Antibacterial properties;.” 2015. Thesis, Anna University. Accessed January 16, 2021. http://shodhganga.inflibnet.ac.in/handle/10603/33539.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

S, Mageswari. “Synthesis characterization of Acrylic and methacrylic polymers And their adhesive and Antibacterial properties;.” 2015. Web. 16 Jan 2021.

Vancouver:

S M. Synthesis characterization of Acrylic and methacrylic polymers And their adhesive and Antibacterial properties;. [Internet] [Thesis]. Anna University; 2015. [cited 2021 Jan 16]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/33539.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

S M. Synthesis characterization of Acrylic and methacrylic polymers And their adhesive and Antibacterial properties;. [Thesis]. Anna University; 2015. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/33539

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

26. Guirous, Houria. Synthèse et caractérisation de la polycaprolactone.

Degree: 2011, Université M'Hamed Bougara Boumerdès

URL: http://dlibrary.univ-boumerdes.dz:8080/jspui/handle/123456789/518

►

71 p. ; ill. ; 30 cm

La polycaprolactone est l'un des polyesters aliphatiques la plus couramment utilisée pour des applications médicales grâce à sa… (more)

Subjects/Keywords: Polyesters; Poly (epsilon-caprolactone); Microencapsulation

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Guirous, H. (2011). Synthèse et caractérisation de la polycaprolactone. (Thesis). Université M'Hamed Bougara Boumerdès. Retrieved from http://dlibrary.univ-boumerdes.dz:8080/jspui/handle/123456789/518

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Guirous, Houria. “Synthèse et caractérisation de la polycaprolactone.” 2011. Thesis, Université M'Hamed Bougara Boumerdès. Accessed January 16, 2021. http://dlibrary.univ-boumerdes.dz:8080/jspui/handle/123456789/518.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Guirous, Houria. “Synthèse et caractérisation de la polycaprolactone.” 2011. Web. 16 Jan 2021.

Vancouver:

Guirous H. Synthèse et caractérisation de la polycaprolactone. [Internet] [Thesis]. Université M'Hamed Bougara Boumerdès; 2011. [cited 2021 Jan 16]. Available from: http://dlibrary.univ-boumerdes.dz:8080/jspui/handle/123456789/518.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Guirous H. Synthèse et caractérisation de la polycaprolactone. [Thesis]. Université M'Hamed Bougara Boumerdès; 2011. Available from: http://dlibrary.univ-boumerdes.dz:8080/jspui/handle/123456789/518

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Queens University

27. Nantais, Corina. Radiopurity measurement of acrylic for the DEAP-3600 dark matter experiment .

Degree: Physics, Engineering Physics and Astronomy, 2014, Queens University

URL: http://hdl.handle.net/1974/8554

► The liquid argon target of the DEAP-3600 dark matter detector is contained by an extremely radiopure acrylic vessel. Alpha decays from the inner surface of… (more)

Subjects/Keywords: poly(methyl methacrylate) ; Pb-210

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APA (6^th Edition):

Nantais, C. (2014). Radiopurity measurement of acrylic for the DEAP-3600 dark matter experiment . (Thesis). Queens University. Retrieved from http://hdl.handle.net/1974/8554

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Nantais, Corina. “Radiopurity measurement of acrylic for the DEAP-3600 dark matter experiment .” 2014. Thesis, Queens University. Accessed January 16, 2021. http://hdl.handle.net/1974/8554.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Nantais, Corina. “Radiopurity measurement of acrylic for the DEAP-3600 dark matter experiment .” 2014. Web. 16 Jan 2021.

Vancouver:

Nantais C. Radiopurity measurement of acrylic for the DEAP-3600 dark matter experiment . [Internet] [Thesis]. Queens University; 2014. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1974/8554.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Nantais C. Radiopurity measurement of acrylic for the DEAP-3600 dark matter experiment . [Thesis]. Queens University; 2014. Available from: http://hdl.handle.net/1974/8554

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Université Laval

28. Isabelle, Maxim. Interactome des intervenants dans le métbolisme du poly(ADP-ribose).

Degree: 2012, Université Laval

URL: http://hdl.handle.net/20.500.11794/24171

► La poly(ADP-ribose) polymerases consistant en une population hétérogène de polymères formés à partir du NAD. La poly(ADP-ribose) glycohydrolase est responsable de la dégradation du poly(ADP-ribose).… (more)

▼ La poly(ADP-ribose) polymerases consistant en une population hétérogène de polymères formés à partir du NAD. La poly(ADP-ribose) glycohydrolase est responsable de la dégradation du poly(ADP-ribose). Les activités enzymatiques de ces enzymes constituent un système de régulation pour différents sentiers métaboliques. En effet, l'interaction démontrée entre le pADPr et de multiples protéines a permis de confirmer un rôle de modulateur de nombreuses voies de signalisation tel que la réparation de l'ADN, apoptose, cycle cellulaire, surveillance de l'intégrité du génome, transcription et modulation de la chromatine. Ainsi, nous avons formulé l'hypothèse que le pADPr pourrait coordonner la réparation des lésions à l'ADN et la progression du cycle cellulaire avec la signalisation d'événement apoptotiques. Une approche efficace constituerait à identifier et caractériser les protéines (intermédiaires) associées au pADPr selon une logique temporelle. Les diverses actions du pADPr sur les processus biologiques dépendent (dans le cas de la majorité du pADPr, soit celui métabolisé par PARP-1) de la gravité des dommages induits à l'ADN. Par conséquent, il existe probablement des points de seuil faisant basculer les voies de signalisation de la réparation vers la mort cellulaire. Une approche réductionniste, dans ce type de problème, ne peut apporter des réponses satisfaisantes. L'utilisation de la protéomique quantitative semble être une approche plus appropriée. Un volet du travail présenté dans cette thèse visait à identifier des partenaires des PARP-1, PARP-2 et PARG dans le but de reconnaître les sentiers biochimiques qui pourraient inclure une composante de poly(ADP-ribosylation) dans leur régulation et définir des interactions fonctionnellement pertinentes. Par la suite, nous avons établi un réseau dynamique des complexes associés au pADPr en fonction du temps suivant un dommage alkylant induit par un stress génotoxique. Ainsi, certains événements modulés par le pADPr ont été analysés et cartographies. De plus, nous avons caractérisé un rôle novateur du pADPr dans la formation des granules de stress suite à un stress génotoxique. En conséquence, nos résultats ont permis d'édifier les premières bases pour la biologie des systèmes de la poly(ADP-ribosyl)ation en fournissant un répertoire d'interactions protéique exhaustif. Advisors/Committee Members: Poirier, Guy.

Subjects/Keywords: Poly (ADP-ribose) polymérase – Métabolisme

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Isabelle, M. (2012). Interactome des intervenants dans le métbolisme du poly(ADP-ribose). (Thesis). Université Laval. Retrieved from http://hdl.handle.net/20.500.11794/24171

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Isabelle, Maxim. “Interactome des intervenants dans le métbolisme du poly(ADP-ribose).” 2012. Thesis, Université Laval. Accessed January 16, 2021. http://hdl.handle.net/20.500.11794/24171.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Isabelle, Maxim. “Interactome des intervenants dans le métbolisme du poly(ADP-ribose).” 2012. Web. 16 Jan 2021.

Vancouver:

Isabelle M. Interactome des intervenants dans le métbolisme du poly(ADP-ribose). [Internet] [Thesis]. Université Laval; 2012. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/20.500.11794/24171.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Isabelle M. Interactome des intervenants dans le métbolisme du poly(ADP-ribose). [Thesis]. Université Laval; 2012. Available from: http://hdl.handle.net/20.500.11794/24171

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

29. Martin, Nicolas. Synthèse et étude cristallochimique de carboxylates d'actinides tétravalents (Th, U, Np) : polymères de coordination et entités moléculaires à haute nucléarité : Synthesis and crystallochemical study of tetravalent actinides (Th, U, Np) based carboxylates : coordination polymers and molecular entities with high nuclearity.

Degree: Docteur es, Chimie des matériaux, 2017, Université Lille I – Sciences et Technologies

URL: http://www.theses.fr/2017LIL10164

►

La compréhension du comportement des actinides dans l’environnement est un enjeu important et très complexe en raison des nombreux phénomènes intervenant dans les processus chimiques.… (more)

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La compréhension du comportement des actinides dans l’environnement est un enjeu important et très complexe en raison des nombreux phénomènes intervenant dans les processus chimiques. Parmi eux, nous pouvons citer la complexation, notamment via les fonctions carboxylates issues des substances humiques présentes dans les sols. En milieu aqueux, les actinides au degré d’oxydation IV sont très sensibles à l’hydrolyse impactant alors leur mobilité. Au cours de ce travail de thèse, nous avons étudié la réactivité de ces actinides(IV) (Th, U et Np) en présence de ligands organiques de type carboxylate aromatique, afin d’enrichir nos connaissances sur les entités formées. Plus de quarante nouveaux composés à base d’actinides(IV) et d’acides polycarboxyliques ont été synthétisés. Leurs structures cristallographiques ont été déterminées par DRX sur monocristal et leurs descriptions sont rapportées. Le contrôle de l’hydrolyse de ces métaux au sein de nos composés a été effectué par une variation de l’acidité en milieu aqueux ou par ajout contrôlé de quantités d’eau dans des solvants organiques. Certains des composés présentés sont construits autour d’assemblages polynucléaires possédant entre 2 et 38 centres métalliques. Pour ces derniers ({U38} et {Np38}), une nouvelle voie de synthèse a été investiguée. Au cours de l’étude de ces différents composés, nous avons mis en évidence les analogies ou les différences existant entre ces actinides, et avons enrichis notamment nos connaissances sur la cristallochimie du neptunium(IV). Enfin, nous avons montré la capacité de ligands N- et O- donneurs à complexer simultanément l’uranium(IV) avec d’autres métaux di- (Mn) ou trivalent (Ln).

Understanding the behavior of actinides in the environment is an important and very complex issue due to phenomena involved in chemical processes. Among them, one can mention the complexation, via carboxylate functions from the humic substances present in the soils. In an aqueous medium, actinides at the oxidation state IV are very sensitive to the hydrolysis process impacting their mobility. This thesis focuses the reactivity of these actinides (IV) (Th, U and Np) in the presence of organic ligands with aromatic carboxylate functions, in order to improve our knowledge about entities formed and linked to such organic linkers.More than forty new compounds based on actinides (IV) and polycarboxylic acids have been synthesized. Their crystallographic structures were determined by single crystal XRD and their descriptions are reported. The control of the hydrolysis of these metals within our compounds has been managed by varying the acidity in aqueous medium or by addition of controlled amount of water in organic solvents. Some of the compounds presented are built from polynuclear moieties having from 2 to 38 metal centers. For the latter ({U38} and {Np38}), a new synthetic pathway was investigated. During the study of these different compounds, we have demonstrated the analogies or the differences existing between these actinides, and have improved our…

Advisors/Committee Members: Loiseau, Thierry (thesis director), Volkringer, Christophe (thesis director).

Subjects/Keywords: Clusters poly-Oxo; 546.42

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Martin, N. (2017). Synthèse et étude cristallochimique de carboxylates d'actinides tétravalents (Th, U, Np) : polymères de coordination et entités moléculaires à haute nucléarité : Synthesis and crystallochemical study of tetravalent actinides (Th, U, Np) based carboxylates : coordination polymers and molecular entities with high nuclearity. (Doctoral Dissertation). Université Lille I – Sciences et Technologies. Retrieved from http://www.theses.fr/2017LIL10164

Chicago Manual of Style (16^th Edition):

Martin, Nicolas. “Synthèse et étude cristallochimique de carboxylates d'actinides tétravalents (Th, U, Np) : polymères de coordination et entités moléculaires à haute nucléarité : Synthesis and crystallochemical study of tetravalent actinides (Th, U, Np) based carboxylates : coordination polymers and molecular entities with high nuclearity.” 2017. Doctoral Dissertation, Université Lille I – Sciences et Technologies. Accessed January 16, 2021. http://www.theses.fr/2017LIL10164.

MLA Handbook (7^th Edition):

Martin, Nicolas. “Synthèse et étude cristallochimique de carboxylates d'actinides tétravalents (Th, U, Np) : polymères de coordination et entités moléculaires à haute nucléarité : Synthesis and crystallochemical study of tetravalent actinides (Th, U, Np) based carboxylates : coordination polymers and molecular entities with high nuclearity.” 2017. Web. 16 Jan 2021.

Vancouver:

Martin N. Synthèse et étude cristallochimique de carboxylates d'actinides tétravalents (Th, U, Np) : polymères de coordination et entités moléculaires à haute nucléarité : Synthesis and crystallochemical study of tetravalent actinides (Th, U, Np) based carboxylates : coordination polymers and molecular entities with high nuclearity. [Internet] [Doctoral dissertation]. Université Lille I – Sciences et Technologies; 2017. [cited 2021 Jan 16]. Available from: http://www.theses.fr/2017LIL10164.

Council of Science Editors:

Martin N. Synthèse et étude cristallochimique de carboxylates d'actinides tétravalents (Th, U, Np) : polymères de coordination et entités moléculaires à haute nucléarité : Synthesis and crystallochemical study of tetravalent actinides (Th, U, Np) based carboxylates : coordination polymers and molecular entities with high nuclearity. [Doctoral Dissertation]. Université Lille I – Sciences et Technologies; 2017. Available from: http://www.theses.fr/2017LIL10164

University of Victoria

30. Chen, Jun. Applications of Thiele's ester derivatives from biological to material.

Degree: Department of Chemistry, 2018, University of Victoria

URL: https://dspace.library.uvic.ca//handle/1828/9403

► Building upon existing synthetic methods, we have optimized the synthesis of Thiele’s methyl ester to an efficient and scalable methodology. As part of a study… (more)

▼ Building upon existing synthetic methods, we have optimized the synthesis of Thiele’s methyl ester to an efficient and scalable methodology. As part of a study of chemo- and regioselective transformations within the Thiele’s ester scaffold, we designed and synthesized a new suite of molecular scaffolds incorporating a broad range (from 123° to 176°) of cleft angles. In addition to this, we compared two competing conceptual models for their ability to rationalize the selective formation of Thiele’s ester and two minor regioisomers which arise during the formation of the target product. We found that radical stabilization arguments (based on Deslongchamps’ seminal work) outperformed the classic frontier molecular orbital theory model in predicting the regioselectivity of Thiele’s ester dimerization. When this method was combined with simple steric arguments, we arrived at a general algorithm to rationalize Thiele type dimerization, including all the known homo- and heterodimerizations in the literature as well as a novel phosphine oxide-containing Thiele acid analogue discovered as part of this thesis work. In order to stimulate the use of Thiele’s ester chemistry in a diverse range of applications, we took advantage of our Thiele’s ester methodology to achieve a mono ester-substituted dicyclopentadiene (colloquially referred to as a “half” Thiele’s ester), and used this as the precursor of a novel functionalized polydicyclopentadiene (fPDCPD) ROMP polymer. The resulting fPDCPD has the highest glass-transition temperature reported for any polydicyclopentadiene material and allows for the facile manipulation of the surface chemistry through alteration of the embedded functional group. A long-term goal in the Wulff lab is to use Thiele’s ester as a scaffold for the generation of conformationally restricted (“peramivir-like”) neuraminidase inhibitors. Setting the groundwork for this, we explored the selectivity of various peramivir derivatives toward group-1 vs. group-2 neuraminidase enzymes. To this end, we coupled a wide range of alkyl chains and aromatic rings with different length and size parameters onto the primary amine of peramivir. We found that our de-guanidinylated peramivir analogues showed a rare target selectivity against group-2 neuraminidases instead of group-1 neuraminidases, which might due to the ring geometry of peramivir as well as the reduced electrostatic interaction between the amino group from our analogues and the Asp147-His150 residues from the enzyme. This suggested that it is possible for group-2 neuraminidases to have a more open 150-cavity state than group-1 neuraminidases. Additionally, the respectable IC50 values for these compounds, together with their significantly reduced polarity (relative to peramivir itself) may prove advantageous from a bioavailability standpoint. Advisors/Committee Members: Wulff, Jeremy Earle (supervisor).

Subjects/Keywords: Thiele's ester; poly dicyclopentadiene; neuraminidase

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Chen, J. (2018). Applications of Thiele's ester derivatives from biological to material. (Thesis). University of Victoria. Retrieved from https://dspace.library.uvic.ca//handle/1828/9403

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Chen, Jun. “Applications of Thiele's ester derivatives from biological to material.” 2018. Thesis, University of Victoria. Accessed January 16, 2021. https://dspace.library.uvic.ca//handle/1828/9403.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Chen, Jun. “Applications of Thiele's ester derivatives from biological to material.” 2018. Web. 16 Jan 2021.

Vancouver:

Chen J. Applications of Thiele's ester derivatives from biological to material. [Internet] [Thesis]. University of Victoria; 2018. [cited 2021 Jan 16]. Available from: https://dspace.library.uvic.ca//handle/1828/9403.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Chen J. Applications of Thiele's ester derivatives from biological to material. [Thesis]. University of Victoria; 2018. Available from: https://dspace.library.uvic.ca//handle/1828/9403

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Open Access Theses and Dissertations