You searched for subject:(Phytosterols).
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Missouri University of Science and Technology
1.
Surapaneni, Naga Mallika.
Effect of food processing techniques on phytosterol, tocopherol and volatile content in soybean and soybean derived foods.
Degree: M.S. in Chemistry, Chemistry, Missouri University of Science and Technology
URL: https://scholarsmine.mst.edu/masters_theses/3650 
► "The overall objective of this research was to monitor the effect of food processing techniques on the phytosterol, tocopherol and volatile content in soybeans and…
(more)
▼ "The overall objective of this research was to monitor the effect of food processing techniques on the phytosterol, tocopherol and volatile content in soybeans and soybean derived foods. In order to meet the primary objective systematic experiments were designed to achieve the following sub-objectives. Develop a rapid method for determination of phytosterols and tocopherols in raw and processed foods, providing greater accuracy, precision and reproducibility. To determine the effect of germination, heat and light on tocopherol and phytosterol content in soybean seeds. To examine the contribution of volatiles to the beany flavor of soybeans" – Statement of Objectives, page 19.
Subjects/Keywords: Phytosterols; Chemistry
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APA (6th Edition):
Surapaneni, N. M. (n.d.). Effect of food processing techniques on phytosterol, tocopherol and volatile content in soybean and soybean derived foods. (Masters Thesis). Missouri University of Science and Technology. Retrieved from https://scholarsmine.mst.edu/masters_theses/3650
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Chicago Manual of Style (16th Edition):
Surapaneni, Naga Mallika. “Effect of food processing techniques on phytosterol, tocopherol and volatile content in soybean and soybean derived foods.” Masters Thesis, Missouri University of Science and Technology. Accessed January 18, 2021.
https://scholarsmine.mst.edu/masters_theses/3650.
Note: this citation may be lacking information needed for this citation format:
No year of publication.
MLA Handbook (7th Edition):
Surapaneni, Naga Mallika. “Effect of food processing techniques on phytosterol, tocopherol and volatile content in soybean and soybean derived foods.” Web. 18 Jan 2021.
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Vancouver:
Surapaneni NM. Effect of food processing techniques on phytosterol, tocopherol and volatile content in soybean and soybean derived foods. [Internet] [Masters thesis]. Missouri University of Science and Technology; [cited 2021 Jan 18].
Available from: https://scholarsmine.mst.edu/masters_theses/3650.
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Council of Science Editors:
Surapaneni NM. Effect of food processing techniques on phytosterol, tocopherol and volatile content in soybean and soybean derived foods. [Masters Thesis]. Missouri University of Science and Technology; Available from: https://scholarsmine.mst.edu/masters_theses/3650
Note: this citation may be lacking information needed for this citation format:
No year of publication.
2.
A. Ruggiero.
EFFECTS OF SAR INDUCERS ON QUALITY AND SAFETY OF THE GRAPE PRODUCTS.
Degree: 2013, Università degli Studi di Milano
URL: http://hdl.handle.net/2434/215698
► The effects of two SAR inducers (benzothiadiazole and chitosan) were investigated on volatile isoprenoid (mono- and sesquiterpene) and phytosterol (β-sitosterol, stigmasterol and campesterol) content in…
(more)
▼ The effects of two SAR inducers (benzothiadiazole and chitosan) were investigated on volatile isoprenoid (mono- and sesquiterpene) and phytosterol (β-sitosterol, stigmasterol and campesterol) content in a grapevine cultivar (Groppello, autochthonous of Lombardy) and in its respective experimental wines. The efficacy of plant activators has been also assayed on the control of the potentially toxigenic grape mycoflora, by measuring the mycotoxin levels in wines.
Advisors/Committee Members: tutor: S. Iametti, co-tutor: M. Iriti, phd coordinator: M.G. Fortina, IAMETTI, STEFANIA, FORTINA, MARIA GRAZIA.
Subjects/Keywords: volatile compounds; phytosterols; Settore BIO/10 - Biochimica
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APA (6th Edition):
Ruggiero, A. (2013). EFFECTS OF SAR INDUCERS ON QUALITY AND SAFETY OF THE GRAPE PRODUCTS. (Thesis). Università degli Studi di Milano. Retrieved from http://hdl.handle.net/2434/215698
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Ruggiero, A.. “EFFECTS OF SAR INDUCERS ON QUALITY AND SAFETY OF THE GRAPE PRODUCTS.” 2013. Thesis, Università degli Studi di Milano. Accessed January 18, 2021.
http://hdl.handle.net/2434/215698.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Ruggiero, A.. “EFFECTS OF SAR INDUCERS ON QUALITY AND SAFETY OF THE GRAPE PRODUCTS.” 2013. Web. 18 Jan 2021.
Vancouver:
Ruggiero A. EFFECTS OF SAR INDUCERS ON QUALITY AND SAFETY OF THE GRAPE PRODUCTS. [Internet] [Thesis]. Università degli Studi di Milano; 2013. [cited 2021 Jan 18].
Available from: http://hdl.handle.net/2434/215698.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Ruggiero A. EFFECTS OF SAR INDUCERS ON QUALITY AND SAFETY OF THE GRAPE PRODUCTS. [Thesis]. Università degli Studi di Milano; 2013. Available from: http://hdl.handle.net/2434/215698
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
McGill University
3.
Howell, Tanya J.
Effects of natural and synthetic phytosterol administration on cholesterol metabolism in normolipidemic humans.
Degree: MS, School of Dietetics and Human Nutrition, 1997, McGill University
URL: https://escholarship.mcgill.ca/downloads/7d278w221.pdf
;
https://escholarship.mcgill.ca/concern/theses/n870zs642
► Phytosterols play an important role in nature and as synthetic supplements for the modification of cholesterol metabolism in humans. The consensus is that the primary…
(more)
▼ Phytosterols play an important role in nature and as synthetic supplements for the modification of cholesterol metabolism in humans. The consensus is that the primary mechanism by which
phytosterols modify lipid profiles is through altering the absorption of cholesterol. This thesis examined the effects of phytosterol mixtures on (i) de novo cholesterol synthesis rates and appearance of de novo cholesterol into the cholesterol ester pool through the use of deuterium incorporation, as well as, (ii) plasma lipid and sterol concentrations in normolipidemic humans. The initial investigation of this thesis compared the effects of diets based on either corn oil, olive oil, or olive oil plus phytosterol mixture on cholesterol metabolism. Each treatment was administered for 10 days in a cross-over design to 16 normolipidemic humans. In addition to confirming prior conclusions that corn oil was more effective than olive oil at decreasing plasma total and LDL-cholesterol concentration, this study was one of the first to determine that the differential effects on cholesterol metabolism observed in humans consuming corn versus olive oil is due, in part, to the higher concentrations of plant sterols naturally found in corn oil. The second study presented in this thesis investigated the differential effects on sterol metabolism of phytosterol mixtures either enriched with sitostanol or sitostanol-free administered for 10 days in 11 normolipidemic humans. The results of this study demonstrated that only the phytosterol mixture containing low doses of sitostanol decreased plasma total and LDL-cholesterol concentrations and increased the circulating HDL/LDL ratios; thus, the sitostanol-enriched phytosterol mixture was a more effective cholesterol-lowering agent.
Advisors/Committee Members: Jones, P. J. H. (Supervisor).
Subjects/Keywords: Phytosterols.; Cholesterol – Metabolism.
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APA (6th Edition):
Howell, T. J. (1997). Effects of natural and synthetic phytosterol administration on cholesterol metabolism in normolipidemic humans. (Masters Thesis). McGill University. Retrieved from https://escholarship.mcgill.ca/downloads/7d278w221.pdf ; https://escholarship.mcgill.ca/concern/theses/n870zs642
Chicago Manual of Style (16th Edition):
Howell, Tanya J. “Effects of natural and synthetic phytosterol administration on cholesterol metabolism in normolipidemic humans.” 1997. Masters Thesis, McGill University. Accessed January 18, 2021.
https://escholarship.mcgill.ca/downloads/7d278w221.pdf ; https://escholarship.mcgill.ca/concern/theses/n870zs642.
MLA Handbook (7th Edition):
Howell, Tanya J. “Effects of natural and synthetic phytosterol administration on cholesterol metabolism in normolipidemic humans.” 1997. Web. 18 Jan 2021.
Vancouver:
Howell TJ. Effects of natural and synthetic phytosterol administration on cholesterol metabolism in normolipidemic humans. [Internet] [Masters thesis]. McGill University; 1997. [cited 2021 Jan 18].
Available from: https://escholarship.mcgill.ca/downloads/7d278w221.pdf ; https://escholarship.mcgill.ca/concern/theses/n870zs642.
Council of Science Editors:
Howell TJ. Effects of natural and synthetic phytosterol administration on cholesterol metabolism in normolipidemic humans. [Masters Thesis]. McGill University; 1997. Available from: https://escholarship.mcgill.ca/downloads/7d278w221.pdf ; https://escholarship.mcgill.ca/concern/theses/n870zs642
University of Georgia
4.
Carr, Elizabeth Catherine.
Bioactive lipid micro-constituents in 20 different commercially-viable pecan [Carya illinoinensis (Wangenh.) K. Koch] cultivars.
Degree: 2016, University of Georgia
URL: http://hdl.handle.net/10724/34077
► Pecans are known for their healthful lipid profile, which includes the lipid micronutrients: tocopherols and phytosterols. Because the pecan has thousands of cultivars and is…
(more)
▼ Pecans are known for their healthful lipid profile, which includes the lipid micronutrients: tocopherols and phytosterols. Because the pecan has thousands of cultivars and is alternate bearing, these nutrient contents can vary. Despite this,
these micronutrients are largely underreported in the USDA National Nutrient Database for Standard Reference (Release 27). Therefore, 20 different commercially-viable pecan cultivars were assayed to determine tocopherol and phytosterol contents along
with effects of crop year and cultivar on these bioactives. Chromatographic methods were employed to determine the levels of tocopherols and phytosterols. All of the tocopherol and most of the phytosterol values determined were lower than that of the
Database, due to the sample variability included in this study. Overall it was discovered that cultivar and crop year can significantly affect the nutrient level of pecans, and thus should be incorporated into the USDA Database
Subjects/Keywords: Pecans; Tocopherols; Phytosterols; Chromatography; Cultivar Variation
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APA (6th Edition):
Carr, E. C. (2016). Bioactive lipid micro-constituents in 20 different commercially-viable pecan [Carya illinoinensis (Wangenh.) K. Koch] cultivars. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/34077
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Carr, Elizabeth Catherine. “Bioactive lipid micro-constituents in 20 different commercially-viable pecan [Carya illinoinensis (Wangenh.) K. Koch] cultivars.” 2016. Thesis, University of Georgia. Accessed January 18, 2021.
http://hdl.handle.net/10724/34077.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Carr, Elizabeth Catherine. “Bioactive lipid micro-constituents in 20 different commercially-viable pecan [Carya illinoinensis (Wangenh.) K. Koch] cultivars.” 2016. Web. 18 Jan 2021.
Vancouver:
Carr EC. Bioactive lipid micro-constituents in 20 different commercially-viable pecan [Carya illinoinensis (Wangenh.) K. Koch] cultivars. [Internet] [Thesis]. University of Georgia; 2016. [cited 2021 Jan 18].
Available from: http://hdl.handle.net/10724/34077.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Carr EC. Bioactive lipid micro-constituents in 20 different commercially-viable pecan [Carya illinoinensis (Wangenh.) K. Koch] cultivars. [Thesis]. University of Georgia; 2016. Available from: http://hdl.handle.net/10724/34077
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
5.
Akaishi, Fernanda Perides.
Validação de metodologias e determinação da composição de fitosteróis em cremes vegetais, farináceos e cafés comercializados em São Paulo.
Degree: Mestrado, Nutrição em Saúde Pública, 2014, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/6/6138/tde-03112014-114457/
;
► Introdução – Os fitosteróis (FS) são esteróis de origem vegetal, reconhecidos como componentes funcionais devido ao seu papel hipocolesterolêmico. A recomendação de ingestão diária desses compostos…
(more)
▼ Introdução – Os fitosteróis (FS) são esteróis de origem vegetal, reconhecidos como componentes funcionais devido ao seu papel hipocolesterolêmico. A recomendação de ingestão diária desses compostos é de 1,6 a 2 g/dia, no entanto há poucos estudos que avaliem os teores desses compostos em alimentos, sendo necessária sua quantificação. Objetivo - O objetivo deste projeto foi desenvolver uma metodologia e determinar os teores de FS em alguns alimentos usualmente consumidos e comercializados em São Paulo. Metodologia Foram avaliadas amostras de creme vegetal sem sal (in natura, e aquecidas a 100o C e 140o C), dos farináceos: farinha de trigo, farinha de milho, farinha de mandioca, amido de milho, café em pó (torras: tradicional, forte e extraforte, descafeinado e gourmet), café solúvel instantâneo, cappuccino e da bebida coada. As amostras, em triplicata, foram submetidas ao processo de saponificação a frio e a matéria insaponificável extraída foi derivatizada e posteriormente injetada em cromatógrafo gasoso. Resultados Os principais FS encontrados foram: -Sitosterol, campesterol e estigmasterol. As maiores médias de teores de FS foram encontradas nos cremes vegetais (186,2 ± 21,7 mg /100g) e nos pós de café moído (92,24 ± 3,95 mg /100g). As farinhas apresentaram teores intermediários, 42,27 ± 7,09 mg /100g; 35,10 ± 10,49 mg /100g; 22,02 ± 1,22 mg /100g; 14,33 ± 3,07 mg /100g para farinha de rosca, milho, trigo e mandioca, respectivamente. As amostras cappuccino (5,73 ± 0,78 mg /100g), café solúvel (4,03 ± 0,84 mg /100g) e amido de milho (3,55 ± 0,8 mg /100g) foram as apresentaram menores teores de FS. Nas amostras de creme vegetal, o processamento térmico reduziu os teores totais de FS das amostras in natura em 10 por cento e 53,7 por cento , para os aquecimentos até 100o C e 140o C, respectivamente. . Não houve influencia do grau de torra e do processo de descafeinização nos teores totais de FS encontrados nas amostras de pó de café moído. Conclusão: De acordo com os resultados obtidos os alimentos com maior teor de fitosteróis são a creme vegetal e o pó de café. Pode-se considerar que o creme vegetal, mesmo sem adição de FS é boa fonte desse nutriente. Nas amostras de café o processamento térmico pouco influenciou nos teores de FS, o mesmo não aconteceu com as amostras de creme vegetal. As mais baixas concentrações de FS foram observadas nas amostras de farinhas, amidos, cappuccino e café em pó solúvel.
Introduction: Phytosterols (PS) are plant sterols, known as functional components due to its hypocholesterolemic role. The recommendation for daily intake of these compounds is 1.6-2 g/day, however there are few studies that evaluate the content of these compounds in foods, requiring its quantification. Objective: the objective of this project was to develop a methodology and determine the content of PS in some foods usually consumed and traded in Sao Paulo. Methodology: Were evaluated samples of: unsalted vegetable cream (in natura, and heated to 100 °C and 140 °C), farinaceous: wheat, corn and cassava flour,…
Advisors/Committee Members: Torres, Elizabeth Aparecida Ferraz da Silva.
Subjects/Keywords: Café; Coffee; Creme Vegetal; Farináceos; Farinaceous; Fitosteróis; Margarine; Phytosterols
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APA (6th Edition):
Akaishi, F. P. (2014). Validação de metodologias e determinação da composição de fitosteróis em cremes vegetais, farináceos e cafés comercializados em São Paulo. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/6/6138/tde-03112014-114457/ ;
Chicago Manual of Style (16th Edition):
Akaishi, Fernanda Perides. “Validação de metodologias e determinação da composição de fitosteróis em cremes vegetais, farináceos e cafés comercializados em São Paulo.” 2014. Masters Thesis, University of São Paulo. Accessed January 18, 2021.
http://www.teses.usp.br/teses/disponiveis/6/6138/tde-03112014-114457/ ;.
MLA Handbook (7th Edition):
Akaishi, Fernanda Perides. “Validação de metodologias e determinação da composição de fitosteróis em cremes vegetais, farináceos e cafés comercializados em São Paulo.” 2014. Web. 18 Jan 2021.
Vancouver:
Akaishi FP. Validação de metodologias e determinação da composição de fitosteróis em cremes vegetais, farináceos e cafés comercializados em São Paulo. [Internet] [Masters thesis]. University of São Paulo; 2014. [cited 2021 Jan 18].
Available from: http://www.teses.usp.br/teses/disponiveis/6/6138/tde-03112014-114457/ ;.
Council of Science Editors:
Akaishi FP. Validação de metodologias e determinação da composição de fitosteróis em cremes vegetais, farináceos e cafés comercializados em São Paulo. [Masters Thesis]. University of São Paulo; 2014. Available from: http://www.teses.usp.br/teses/disponiveis/6/6138/tde-03112014-114457/ ;
Universidade Estadual de Campinas
6.
Okuro, Paula Kiyomi, 1987-.
Papel da lecitina no desenvolvimento de oleogéis : efeito da fase orgânica e estudo de sistemas híbridos = Role of lecithin in oleogel formation: effect of organic phase and study of hybrid systems: Role of lecithin in oleogel formation : effect of organic phase and study of hybrid systems.
Degree: 2018, Universidade Estadual de Campinas
URL: http://repositorio.unicamp.br/jspui/handle/REPOSIP/334642
► Abstract: The proposal of alternative routes for the conventional oil structuring represents an important topic, since conventional routes involve the formation of crystalline colloidal networks…
(more)
▼ Abstract: The proposal of alternative routes for the conventional oil structuring represents an important topic, since conventional routes involve the formation of crystalline colloidal networks that usually are comprised of high levels of saturated and/or trans fatty acids. Oleogels are proposed as alternative because they promote gelation of liquid solvents through 3D network formation. Biological phospholipids (also called lecithins), in particular phosphatidylcholine, were evaluated with different solvents (hexadecane and medium and long chain triacylglycerol) to form oleogels. It was verified that among the studied solvents only hexadecane led to gel formation. The characterization of nano and microstructure and rheological (isothermal and non-isothermal conditions) were investigated. The effect of lecithin concentration and inclusion of water or citric acid (primers) to modify the system were also evaluated in order to optimize the mechanical properties of the gel. The understanding of the variables involved in oleogel formation in a model system was sought so that the production of oleogels with food grade components would be possible from this first stage. Therefore, hybrid systems in the presence of lecithin with other oleogelator(s) were proposed. The combination between lecithin and sterol(ester)s was investigated by small angle X-ray scattering, microscopy, differential scanning calorimetry, rheological and uniaxial compression tests. At nanoscale it was possible to observe that the building blocks were modified according to the addition of lecithin as well as the solvent type. Thermal and mechanical behaviours were also influenced by the presence of lecithin which led to the reduction of the melting temperature, a longer time required for crystallization and the apparent reduction of gel hardness. From these results we hypothesized that lecithin would dispute binding sites involved in the formation of complexes between ß-sitosterol and 'gama'-oryzanol, suppressing the formation of the typical fibrillar structures. However, still in the search for a synergistic system involving lecithin, a scanning with different types of waxes was performed. Among the waxes tested, fruit wax, which stands out for its unique composition (fatty acids and alcohols), showed promising results in oil structuring in combination with lecithin. The presence of lecithin affected the thermal behavior promoting a delay in the crystallization and gelation. An improvement in the mechanical properties (higher elastic modulus, tixotropy and oil binding capacity) at certain ratios between the components was observed when compared with the systems formed only with the wax. Moreover, lecithin affected the crystalline habit (size and shape) of fruit wax. In summary, this study initially had a fundamental approach based on understanding of lecithin as a main oleogelator, and a further investigation of more complex systems focusing in lecithin combined with other components also linked to nutritional and technological functionalities.…
Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS (CRUESP), Cunha, Rosiane Lopes da, 1967- (advisor), Vicente, António Augusto (coadvisor), Universidade Estadual de Campinas. Faculdade de Engenharia de Alimentos (institution), Programa de Pós-Graduação em Engenharia de Alimentos (nameofprogram), Ribeiro, Ana Paula Badan (committee member), Chiu, Ming Chih (committee member), Masuchi, Monise Helen (committee member).
Subjects/Keywords: Viscoelasticidade; Estruturação de óleos; Fitosterois; Ceras; Viscoelasticity; Oil structuring; Phytosterols; Waxes
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APA (6th Edition):
Okuro, Paula Kiyomi, 1. (2018). Papel da lecitina no desenvolvimento de oleogéis : efeito da fase orgânica e estudo de sistemas híbridos = Role of lecithin in oleogel formation: effect of organic phase and study of hybrid systems: Role of lecithin in oleogel formation : effect of organic phase and study of hybrid systems. (Thesis). Universidade Estadual de Campinas. Retrieved from http://repositorio.unicamp.br/jspui/handle/REPOSIP/334642
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Okuro, Paula Kiyomi, 1987-. “Papel da lecitina no desenvolvimento de oleogéis : efeito da fase orgânica e estudo de sistemas híbridos = Role of lecithin in oleogel formation: effect of organic phase and study of hybrid systems: Role of lecithin in oleogel formation : effect of organic phase and study of hybrid systems.” 2018. Thesis, Universidade Estadual de Campinas. Accessed January 18, 2021.
http://repositorio.unicamp.br/jspui/handle/REPOSIP/334642.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Okuro, Paula Kiyomi, 1987-. “Papel da lecitina no desenvolvimento de oleogéis : efeito da fase orgânica e estudo de sistemas híbridos = Role of lecithin in oleogel formation: effect of organic phase and study of hybrid systems: Role of lecithin in oleogel formation : effect of organic phase and study of hybrid systems.” 2018. Web. 18 Jan 2021.
Vancouver:
Okuro, Paula Kiyomi 1. Papel da lecitina no desenvolvimento de oleogéis : efeito da fase orgânica e estudo de sistemas híbridos = Role of lecithin in oleogel formation: effect of organic phase and study of hybrid systems: Role of lecithin in oleogel formation : effect of organic phase and study of hybrid systems. [Internet] [Thesis]. Universidade Estadual de Campinas; 2018. [cited 2021 Jan 18].
Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/334642.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Okuro, Paula Kiyomi 1. Papel da lecitina no desenvolvimento de oleogéis : efeito da fase orgânica e estudo de sistemas híbridos = Role of lecithin in oleogel formation: effect of organic phase and study of hybrid systems: Role of lecithin in oleogel formation : effect of organic phase and study of hybrid systems. [Thesis]. Universidade Estadual de Campinas; 2018. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/334642
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Sardar Patel University
7.
Jadav, Kalpeshkumar Ganpatsinh.
Studies on oleochemicals of industrial
significance.
Degree: chemistry, 2010, Sardar Patel University
URL: http://shodhganga.inflibnet.ac.in/handle/10603/34776
None newline
reference given in the end of each chapter.
Appendix 353p.
Advisors/Committee Members: Toliwal,S D.Subjects/Keywords: bacteriostatic; chromophores; oleochemicals; phytosterols
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APA (6th Edition):
Jadav, K. G. (2010). Studies on oleochemicals of industrial
significance. (Thesis). Sardar Patel University. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/34776
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Jadav, Kalpeshkumar Ganpatsinh. “Studies on oleochemicals of industrial
significance.” 2010. Thesis, Sardar Patel University. Accessed January 18, 2021.
http://shodhganga.inflibnet.ac.in/handle/10603/34776.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Jadav, Kalpeshkumar Ganpatsinh. “Studies on oleochemicals of industrial
significance.” 2010. Web. 18 Jan 2021.
Vancouver:
Jadav KG. Studies on oleochemicals of industrial
significance. [Internet] [Thesis]. Sardar Patel University; 2010. [cited 2021 Jan 18].
Available from: http://shodhganga.inflibnet.ac.in/handle/10603/34776.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Jadav KG. Studies on oleochemicals of industrial
significance. [Thesis]. Sardar Patel University; 2010. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/34776
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Universidade de Brasília
8.
Tatiana Evangelista da Silva Rocha.
Composição de ácidos graxos e de fitoesteróis em frutos de quatro variedades de abacate (Persea Americana MILLl).
Degree: 2008, Universidade de Brasília
URL: http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4089
► Os fitosteróis, presentes na porção insaponificável das gorduras dietéticas, têm sido apontados como fator protetor contra as doenças cardiovasculares e o ácido graxo oléico tem…
(more)
▼ Os fitosteróis, presentes na porção insaponificável das gorduras dietéticas, têm sido apontados como fator protetor contra as doenças cardiovasculares e o ácido graxo oléico tem sido estudado com evidências de efeitos positivos na prevenção e tratamento de doenças crônicas. Devido à elevada riqueza nestes dois componentes apresentada pelos frutos de abacate, este estudo teve como objetivo avaliar quatro variedades desta fruta quanto ao seu conteúdo de ácidos graxos e de fitosteróis. Dentre as variedades estudadas (Wagner, Fortuna, Fuerte e Hass), Fuerte (20,093,16g/ 100g) e Wagner (20,991,43g/ 100g) foram as que apresentaram maiores concentrações lipídico (p <0,05), e Fuerte foi a variedade mais rica em ácido oléico (63,16 0,11%). O perfil de fitoesteróis foi significativamente diferente entre as quatro variedades analisadas. O -sitosterol foi o mais abundante dos quatro esteróis identificados no estudo, e a variedade Fuerte foi a mais rica nesta molécula (207,2117,63mg/100g) (p <0,05). Traços de colesterol foram encontrados nas variedades Fortuna e Fuerte. O conteúdo lipídico e de fitoesteróis elevaram-se com a evolução da maturação do fruto, porém o perfil dos ácidos graxos permaneceu inalterado. Os conteúdos lipídico, de ácido oléico e de -sitosterol foram maiores no período final da safra. Os resultados deste trabalho indicam que, dentre as variedades estudadas, Fuerte é a mais indicada para consumo visando os benefícios comprovados deste ácido graxo e dos fitoesteróis à saúde.
The phytosterols, present in the non saponifiable portion of dietary fats have been pointed out as protective against cardiovascular diseases. The oleic acid is another compound with positive effects on the treatment and prevention of chronic diseases. Therefore, this study has evaluated four varieties of avocado (Persea americana Mill) for the composition of fatty acids and phytosterols. Among analyzed varieties (Wagner, Fuerte, Fortuna and Hass) analysed, Fuerte (20.093.16g/ 100g) and Wagner (20.991.43g/ 100g) presented the highest lipid content (p <0.05). Fuerte showed the highest content of oleic acid (63.16 0.11%). The amount of phytosterols was significantly different among the four analyzed varieties, being - sitosterol the most abundant out of the four sterols identified in the study, and Fuerte the richest variety in this compound (207.2117.63mg/100g) (p <0.05). Traces of cholesterol were found in the Fortuna and Fuerte varieties. The content of lipids and phytosterols increased with the ripening of the fruit; however, the amount of the fatty acid remained unchanged. The content of total lipids, oleic acids and -sitosterol were higher at the end of the harvest period. The results of this study indicate that the Fuerte variety may be the most appropriated fruit for consumption, aiming at the proven benefits of fatty acid and the phytosterols to health.
Advisors/Committee Members: Marina Kiyomi Ito, Elaine Meire de Assis, Tadeu Graciolli Guimarães.
Subjects/Keywords: ácidos graxos; lipídios; NUTRICAO; fatty acids; phytosterols; lipids; fitosteróis; avocado; abacate
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APA (6th Edition):
Rocha, T. E. d. S. (2008). Composição de ácidos graxos e de fitoesteróis em frutos de quatro variedades de abacate (Persea Americana MILLl). (Thesis). Universidade de Brasília. Retrieved from http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4089
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Rocha, Tatiana Evangelista da Silva. “Composição de ácidos graxos e de fitoesteróis em frutos de quatro variedades de abacate (Persea Americana MILLl).” 2008. Thesis, Universidade de Brasília. Accessed January 18, 2021.
http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4089.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Rocha, Tatiana Evangelista da Silva. “Composição de ácidos graxos e de fitoesteróis em frutos de quatro variedades de abacate (Persea Americana MILLl).” 2008. Web. 18 Jan 2021.
Vancouver:
Rocha TEdS. Composição de ácidos graxos e de fitoesteróis em frutos de quatro variedades de abacate (Persea Americana MILLl). [Internet] [Thesis]. Universidade de Brasília; 2008. [cited 2021 Jan 18].
Available from: http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4089.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Rocha TEdS. Composição de ácidos graxos e de fitoesteróis em frutos de quatro variedades de abacate (Persea Americana MILLl). [Thesis]. Universidade de Brasília; 2008. Available from: http://bdtd.bce.unb.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=4089
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Newcastle
9.
Micallef, Michelle.
Phytosterols and omega-3 polyunsaturated fatty acids for cardiovascular health in hyperlipidemia.
Degree: PhD, 2010, University of Newcastle
URL: http://hdl.handle.net/1959.13/934708
► Research Doctorate - Doctor of Philosophy (PhD)
Atherosclerosis is a major factor influencing morbidity and mortality worldwide. The pathogenesis of atherosclerosis has been extensively investigated…
(more)
▼ Research Doctorate - Doctor of Philosophy (PhD)
Atherosclerosis is a major factor influencing morbidity and mortality worldwide. The pathogenesis of atherosclerosis has been extensively investigated however treatment modalities have not changed much over the past decade. Prevention of atherosclerosis and its complications, both primary and secondary, are based mainly on controlling the various cardiovascular risk factors. Treating combined hyperlipidemia, and in particular reducing LDL-cholesterol and triglyceride levels, is established as a highly efficacious means of reducing both morbidity and mortality from cardiovascular disease. With the increased emphasis on various lipoprotein sub fractions, many patients need to consider combining treatments to achieve recommendations. Although statins can be an effective treatment for hyperlipidemia, they may not be sufficient to achieve the recommended LDL-cholesterol and triglyceride goals as set out by national governing bodies. This thesis examines the lipid, inflammatory and cardiovascular esponse to concomitant supplementation with phytosterols and omega-3 fatty acids in combined hyperlipidemia. Phytosterols and omega-3 fatty acids are functional ingredients with potential cardiovascular benefits. Phytosterols inhibit cholesterol absorption, thereby reducing total-cholesterol and LDL-cholesterol. The consumption of 1.5-2.0g/day of phytosterols can result in a 10-15% reduction in LDL-cholesterol within a three week period, in hyperlipidemic populations. The added benefit of phytosterol supplementation has been demonstrated in individuals already taking statin medications. Omega-3 fatty acid supplementation has strong hypotriglyceridemic properties, and provides benefits in other risk factors associated with cardiovascular disease, such as anti-thrombotic and antiinflammatory function. Given the propensity of hyperlipidemia to manifest in high risk individuals and populations alike, there is a plausible role for combining phytosterols and omega-3 fatty acids supplementation. A series of clinical trials were undertaken to explore the plasma lipid, inflammatory and overall cardiovascular response to combined supplementation with phytosterols and omega-3 fatty acids rich in either EPA or DHA. This particular dietary combination of functional ingredients was designed to optimise improvements in plasma lipid profile in individuals with combined hyperlipidemia. Findings from this thesis show that the combined supplementation of phytosterols and various omega-3 fatty acids reduces total-cholesterol, LDL-cholesterol, triglycerides and increases HDL-cholesterol, greater than the supplementation of either function ingredient alone. Furthermore, a number of circulating inflammatory mediators were analysed showing significant reductions in response to the combined dietary treatment. Overall cardiovascular risk was reduced by an average of 20%. Interestingly, the combination of phytosterols and DHA was most effective in reducing triglyceride levels and inflammatory mediators,…
Advisors/Committee Members: University of Newcastle. Faculty of Health, School of Biomedical Sciences and Pharmacy.
Subjects/Keywords: hyperlipidemia; phytosterols; omega-3 fatty acids; inflammation; cardiovascular disease
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APA (6th Edition):
Micallef, M. (2010). Phytosterols and omega-3 polyunsaturated fatty acids for cardiovascular health in hyperlipidemia. (Doctoral Dissertation). University of Newcastle. Retrieved from http://hdl.handle.net/1959.13/934708
Chicago Manual of Style (16th Edition):
Micallef, Michelle. “Phytosterols and omega-3 polyunsaturated fatty acids for cardiovascular health in hyperlipidemia.” 2010. Doctoral Dissertation, University of Newcastle. Accessed January 18, 2021.
http://hdl.handle.net/1959.13/934708.
MLA Handbook (7th Edition):
Micallef, Michelle. “Phytosterols and omega-3 polyunsaturated fatty acids for cardiovascular health in hyperlipidemia.” 2010. Web. 18 Jan 2021.
Vancouver:
Micallef M. Phytosterols and omega-3 polyunsaturated fatty acids for cardiovascular health in hyperlipidemia. [Internet] [Doctoral dissertation]. University of Newcastle; 2010. [cited 2021 Jan 18].
Available from: http://hdl.handle.net/1959.13/934708.
Council of Science Editors:
Micallef M. Phytosterols and omega-3 polyunsaturated fatty acids for cardiovascular health in hyperlipidemia. [Doctoral Dissertation]. University of Newcastle; 2010. Available from: http://hdl.handle.net/1959.13/934708
University of Guelph
10.
Mirzaee Ghazani, Saeed.
The Influence of Traditional and Minimal Refining on the Minor Constituents of Canola Oil.
Degree: MS, Department of Food Science, 2012, University of Guelph
URL: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/4774
► The minimal refining method described in this study made it possible to neutralize crude canola oil using some weaker alkali such as Ca(OH)2, MgO and…
(more)
▼ The minimal refining method described in this study made it possible to neutralize crude canola oil using some weaker alkali such as Ca(OH)2, MgO and Na2siO3 as an alternative for NaOH. After citric acid degumming, more than 98% of phosphorous content was removed from crude oil. The free fatty acid content after minimal neutralization with calcium hydroxide decreased from 0.50 to 0.03%. Other quality parameters such as peroxide value, anisidine value and chlorophyll content were within commercially acceptable levels. The use of Trisyl silica and Magnesol R60 made it possible to remove the hot water washing step and to decrease the amount of remaining soap to less than 10 ppm. There was no significant change in chemical characteristics of canola oil after wet and dry bleaching. During traditional neutralization, total tocopherol loss was 19.6% while minimal refining with Ca(OH)2, MgO and Na2siO3 resulted in 7.0, 2.6 and 0.9 % reduction in total tocopherols. Traditional refining removed 23.6% of total free sterols, although after minimal refining free sterols content did not change significantly (p<0.05). Both traditional and minimal refining resulted in almost complete removal of polyphenols from canola oil. Total
phytosterols and tocopherols in two cold press canola oils were 7700, 8400 mg/kg and 370, 350 mg/kg, respectively. Total
phytosterols and tocopherols contents in solvent extracted canola oil were 9500, 500 mg/kg, respectively. The minimal refining method described in this study was a new practical approach to remove undesirable components from crude canola oil confirmed with commercial refining standards as well as preserving more healthy minor components.
Advisors/Committee Members: Marangoni, Alejandro (advisor).
Subjects/Keywords: Minimal refining; canola oil; phytosterols; tocopherols; polyphenols; gas chromatography
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APA (6th Edition):
Mirzaee Ghazani, S. (2012). The Influence of Traditional and Minimal Refining on the Minor Constituents of Canola Oil. (Masters Thesis). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/4774
Chicago Manual of Style (16th Edition):
Mirzaee Ghazani, Saeed. “The Influence of Traditional and Minimal Refining on the Minor Constituents of Canola Oil.” 2012. Masters Thesis, University of Guelph. Accessed January 18, 2021.
https://atrium.lib.uoguelph.ca/xmlui/handle/10214/4774.
MLA Handbook (7th Edition):
Mirzaee Ghazani, Saeed. “The Influence of Traditional and Minimal Refining on the Minor Constituents of Canola Oil.” 2012. Web. 18 Jan 2021.
Vancouver:
Mirzaee Ghazani S. The Influence of Traditional and Minimal Refining on the Minor Constituents of Canola Oil. [Internet] [Masters thesis]. University of Guelph; 2012. [cited 2021 Jan 18].
Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/4774.
Council of Science Editors:
Mirzaee Ghazani S. The Influence of Traditional and Minimal Refining on the Minor Constituents of Canola Oil. [Masters Thesis]. University of Guelph; 2012. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/4774
University of Connecticut
11.
Kunces, Laura J.
The Effects of Phytosterols on Lipoprotein Particle Size.
Degree: MS, Kinesiology, 2012, University of Connecticut
URL: https://opencommons.uconn.edu/gs_theses/285
► Phytosterols (PS) have become a recent popular medication alternative for treatment of hypercholesterolemia and have proven effective. Whether PS decrease risk of cardiovascular disease…
(more)
▼ Phytosterols (PS) have become a recent popular medication alternative for treatment of hypercholesterolemia and have proven effective. Whether PS decrease risk of cardiovascular disease through other mechanisms, such as lipoprotein particle size and inflammatory markers, remains unclear. PURPOSE: The primary aim of this study was to examine the effects of two forms of PS in milk on lipoprotein particle size, inflammatory markers and fat-soluble vitamins. METHODS: Twenty subjects (13 males, 7 females; age; 55±6.1 years, height; 169±10 cm, weight; 77.9±16.9 kg, BMI; 27.3) consumed 16oz of cow’s milk daily for 12 weeks. The three sequential four-week phases consisted of 2% cow’s milk, 2 grams/day of ‘unaided’ PS in skim milk, and 2 grams/day of ‘aided’ triglyceride recrystallized PS (TRP) in fat-free milk. Blood was taken after each phase for NMR lipoprotein particle size analysis, lipid panel, glucose, insulin, inflammatory markers, and fat-soluble vitamins. RESULTS: Subjects maintained body weight and composition, habitual diet, and physical activity throughout the twelve weeks (p>0.05). Total LDL particle concentrations from NMR decreased to a greater extent with TRP (-15%) compared to unaided (-5%) PS (p
Advisors/Committee Members: Carl M. Maresh, William J. Kraemer, Jeff S. Volek.
Subjects/Keywords: Phytosterols; Lipoprotein particle size; cholesterol; inflammation; fat-soluble vitamins
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APA (6th Edition):
Kunces, L. J. (2012). The Effects of Phytosterols on Lipoprotein Particle Size. (Masters Thesis). University of Connecticut. Retrieved from https://opencommons.uconn.edu/gs_theses/285
Chicago Manual of Style (16th Edition):
Kunces, Laura J. “The Effects of Phytosterols on Lipoprotein Particle Size.” 2012. Masters Thesis, University of Connecticut. Accessed January 18, 2021.
https://opencommons.uconn.edu/gs_theses/285.
MLA Handbook (7th Edition):
Kunces, Laura J. “The Effects of Phytosterols on Lipoprotein Particle Size.” 2012. Web. 18 Jan 2021.
Vancouver:
Kunces LJ. The Effects of Phytosterols on Lipoprotein Particle Size. [Internet] [Masters thesis]. University of Connecticut; 2012. [cited 2021 Jan 18].
Available from: https://opencommons.uconn.edu/gs_theses/285.
Council of Science Editors:
Kunces LJ. The Effects of Phytosterols on Lipoprotein Particle Size. [Masters Thesis]. University of Connecticut; 2012. Available from: https://opencommons.uconn.edu/gs_theses/285
University of Newcastle
12.
Ferguson, Jessica Jayne Anne.
Enhancing the lipid-lowering potential of phytosterols in hypercholesterolaemic individuals.
Degree: PhD, 2019, University of Newcastle
URL: http://hdl.handle.net/1959.13/1406291
► Research Doctorate - Doctor of Philosophy (PhD)
Cardiovascular disease (CVD) remains the leading cause of death worldwide, accounting for over one third of all deaths.…
(more)
▼ Research Doctorate - Doctor of Philosophy (PhD)
Cardiovascular disease (CVD) remains the leading cause of death worldwide, accounting for over one third of all deaths. Since CVD is chronic, complex and multifaceted in pathological pathways, effective risk reduction and prevention strategies ought to be multi-targeted and easily compliable. CVD encompasses a vast complexion of non-modifiable and modifiable risk factors, the latter of which can be somewhat modulated by diet, physical activity and lifestyle changes. Abnormal blood lipids (dyslipidaemia) remain a key modifiable risk factor underpinning the pathological mechanism of atherosclerosis, a key manifestation of CVD. Changes to diet and lifestyle remain the first line of treatment for managing dyslipidaemia, however, pharmacological intervention is often indicated due to poor long-term adherence and inadequate results of solo diet and lifestyle management. Pharmacological intervention is also riddled with complications that impede long-term adherence and sustainability such as side effects, intolerance to statins, poor adherence and cost. Nutraceuticals, also referred to as bioactives, are potential alternatives and/or adjunct therapies to diet, lifestyle and/or pharmacological treatments; given their ability to effectively down-regulate multiple pathological mechanisms (elevated blood lipids, chronic low-grade inflammation, glycaemic parameters, hypertension) involved in CVD development. Phytosterols and phytostanols (PS) are a family of well-established cholesterol-lowering bioactive compounds commonly used in functional foods for the management of elevated bad cholesterol, namely low-density lipoprotein cholesterol (LDL-C). Foods enriched with 2 g PS when consumed daily can effectively lower LDL-C by 8-10%, with no effects on other blood lipids or CVD risk factors. The primary aim of my PhD project was to enhance lipid-modulating potential of phytosterols with the secondary aims of improving compliance and concurrently targeting other CVD risk factors for improved heart health. Given the widespread use and acceptance of PS enriched foods as a therapy, the first aim of my PhD project, presented in chapter 3, was to investigate whether the type of carrier fat used in common PS enriched products (i.e. vegetable fat spreads and dairy products) was a determinant of the cholesterol-lowering potential of PS. A systematic review and meta-analysis was conducted and we observed that most PS enriched products are based on either rapeseed/canola oil, sunflower/soybean oil or dairy fat. Since the dietary fat type is known to modulate blood cholesterol levels, it was logical to hypothesize that the carrier fat used in PS enriched functional foods may contribute to the overall reduction in LDL-C. The meta-analysis revealed that PS enriched products based on rapeseed/canola oil fat type had a significantly greater reduction (0.1 mmol/L or 26%) in LDL-C when compared to the sunflower/soybean oil. This is clinically significant since an average reduction in LDL-C following…
Advisors/Committee Members: University of Newcastle. Faculty of Health & Medicine, School of Biomedical Sciences and Pharmacy.
Subjects/Keywords: phytosterols; cholesterol; cardiovascular disease; curcumin; oat beta-glucan; thesis by publication
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APA (6th Edition):
Ferguson, J. J. A. (2019). Enhancing the lipid-lowering potential of phytosterols in hypercholesterolaemic individuals. (Doctoral Dissertation). University of Newcastle. Retrieved from http://hdl.handle.net/1959.13/1406291
Chicago Manual of Style (16th Edition):
Ferguson, Jessica Jayne Anne. “Enhancing the lipid-lowering potential of phytosterols in hypercholesterolaemic individuals.” 2019. Doctoral Dissertation, University of Newcastle. Accessed January 18, 2021.
http://hdl.handle.net/1959.13/1406291.
MLA Handbook (7th Edition):
Ferguson, Jessica Jayne Anne. “Enhancing the lipid-lowering potential of phytosterols in hypercholesterolaemic individuals.” 2019. Web. 18 Jan 2021.
Vancouver:
Ferguson JJA. Enhancing the lipid-lowering potential of phytosterols in hypercholesterolaemic individuals. [Internet] [Doctoral dissertation]. University of Newcastle; 2019. [cited 2021 Jan 18].
Available from: http://hdl.handle.net/1959.13/1406291.
Council of Science Editors:
Ferguson JJA. Enhancing the lipid-lowering potential of phytosterols in hypercholesterolaemic individuals. [Doctoral Dissertation]. University of Newcastle; 2019. Available from: http://hdl.handle.net/1959.13/1406291
13.
Alsaif, Maha Jr.
Long-term consumption of wild rice (Zizania palustris L.) in combination with phytosterols prevents atherosclerosis in LDL receptor-knock-out mice.
Degree: Human Nutritional Sciences, 2014, University of Manitoba
URL: http://hdl.handle.net/1993/23506
► Atherosclerosis is the primary underlying pathology of CVD. Dietary treatment may be considered as one of the initial steps in the prevention of atherosclerosis. Replacing…
(more)
▼ Atherosclerosis is the primary underlying pathology of CVD. Dietary treatment may be considered as one of the initial steps in the prevention of atherosclerosis. Replacing refined carbohydrate source of a cholesterol- enriched diet with antioxidant rich whole grain and inclusion of phytonutrition in the diet such as wild rice and
phytosterols may reduce cardiovascular risk factors. The wild rice (Zizania palustris L.), an annual plant native to aquatic areas of the northern America, receives much attention by researchers because of its potent nutritional and phytochemical contents. Furthermore, another dietary component with cardiovascular benefits is the inclusion of plant sterols in our daily diet. The aim of this study was to investigate the antiatherogenic activity of wild rice in combination with
phytosterols in LDL-r-KO mice. Male LDL-r-KO mice were divided into 4 groups receiving one of the following experimental diets for 20 weeks: 1. Atherogenic diet, 2.Wild rice (as the main source of dietary carbohydrates) diet, 3. 2%
Phytosterols-enriched diet and 4. Diet containing both wild rice and 2 %
phytosterols. Blood samples were collected through jugular vein during study, and at sacrifice through cardiac puncture; the heart and fecal materials were collected and used for biochemical and histological examinations. The supplementation of wild rice in combination with
phytosterols to an atherogenic diet for up to 20 weeks significantly reduced the total plasma concentrations of cholesterol (TC) in LDLr-KO mice. However, there was no significant difference in triglyceride (TG) in wild rice in combination with
phytosterols after 20 week exposure of diet. Further, wild rice in combination with
phytosterols resulted in increased fecal excretion of cholesterol. Also, there was reduction in the development of atherosclerotic lesion in the group of mice supplemented with wild rice in combination with 2%
phytosterols (w/w). Our data support that combination of plant sterols and wild rice does not have additive effect in lowering cardiovascular risk.
Advisors/Committee Members: Moghadasian, Mohammed (Human Nutritional Sciences) (supervisor), Thiyam, Usha (Human Nutritional Sciences) Beta,Trust (Food Sciences) (examiningcommittee).
Subjects/Keywords: Wild rice; Phytosterols; Atherosclerosis
…fiber, vitamins, minerals, phytosterols,
and antioxidant phenolic compounds (Okarter and… …phytosterols treatment in a responsive animal model. In Xu et al., (2008) study, there
were… …efforts made to utilize previous experiences with phytosterols therapy in apo E-KO
28
mice… …of dietary phytosterols using cDNA microarray techniques. Phytosterols
treatment was…
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APA (6th Edition):
Alsaif, M. J. (2014). Long-term consumption of wild rice (Zizania palustris L.) in combination with phytosterols prevents atherosclerosis in LDL receptor-knock-out mice. (Masters Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/23506
Chicago Manual of Style (16th Edition):
Alsaif, Maha Jr. “Long-term consumption of wild rice (Zizania palustris L.) in combination with phytosterols prevents atherosclerosis in LDL receptor-knock-out mice.” 2014. Masters Thesis, University of Manitoba. Accessed January 18, 2021.
http://hdl.handle.net/1993/23506.
MLA Handbook (7th Edition):
Alsaif, Maha Jr. “Long-term consumption of wild rice (Zizania palustris L.) in combination with phytosterols prevents atherosclerosis in LDL receptor-knock-out mice.” 2014. Web. 18 Jan 2021.
Vancouver:
Alsaif MJ. Long-term consumption of wild rice (Zizania palustris L.) in combination with phytosterols prevents atherosclerosis in LDL receptor-knock-out mice. [Internet] [Masters thesis]. University of Manitoba; 2014. [cited 2021 Jan 18].
Available from: http://hdl.handle.net/1993/23506.
Council of Science Editors:
Alsaif MJ. Long-term consumption of wild rice (Zizania palustris L.) in combination with phytosterols prevents atherosclerosis in LDL receptor-knock-out mice. [Masters Thesis]. University of Manitoba; 2014. Available from: http://hdl.handle.net/1993/23506
14.
Babawale, Elizabeth.
The effects of dietary phytosterol and cholesterol concentration in infant formula on circulating cholesterol levels, cholesterol absorption and synthesis as well as other health biomarkers using neonate piglets.
Degree: Food Science, 2018, University of Manitoba
URL: http://hdl.handle.net/1993/32870
► High cholesterol synthesis at infancy could lead to hypercholesterolemia later in life. However, high synthesis at infancy could be traced to low dietary cholesterol especially…
(more)
▼ High cholesterol synthesis at infancy could lead to hypercholesterolemia later in life. However, high synthesis at infancy could be traced to low dietary cholesterol especially in the formula-fed infants because they consume diets high in phytosterol (PS), a known cholesterol absorption inhibitor. High PS levels are found in vegetable oil used in infant foods. Human milk contains significant amounts of cholesterol ranging from 0.26-0.28mmol/L, compared to the very low levels in infant formula (IF) which can be as low as 0.08mmol/L. Therefore, the objective of this study was to investigate the effect of IF containing different levels of PS and cholesterol on circulating cholesterol levels, cholesterol absorption and synthesis, and other related health biomarkers using neonate piglets as model for human infants. A total of 32 piglets were used with 8 piglets per group fed diets of the following composition: (i) high in PS; low in cholesterol (HiPSLoChol), (ii) high in PS; high in cholesterol (HiPSHiChol), (iii) low in PS; high in cholesterol (LoPSHiChol) and (iv) low in PS; low in cholesterol (LoPSLoChol). After 21 days of study, various tissues were collected for analysis. In plasma and liver, cholesterol levels were higher p<0.05 in LoPSHiChol compared to LoPSLoChol diet group. Cholesterol synthesis levels in plasma, liver and distal intestine were also lower p<0.05 in the LoPSHiChol diet group compared to the HiPSLoChol and LoPSLoChol diet groups. Circulating lipid profiles after 3wks on each diet were compared across different dietary treatments. No significant differences were observed in circulating total cholesterol levels across the treatments. However, circulating levels of LDL-C in HiPSHiChol and LoPSHiChol increased (p<0.05) compared to the HiPSLoChol group. Plasma fatty acids shows higher (P<0.05) docosahexanoic acid (DHA) in HiPSLoChol diet compared to LoPSHiChol diet group. Also, ratio of n-3 to n-6 fatty acids was higher (P<0.05) in HiPSLoChol diet group compared to LoPSHiChol diet group. Beta and gamma tocopherols were lower in LoPSHiChol and LoPSLoChol diet groups compared to the remaining two groups. Other health biomarkers parameters measured such as antioxidant capacity, apolipoprotein A1 and B, C-reactive protein, insulin, glucagon-like peptide 1, fructosamine and LDL particle size were not significantly different across diets. In conclusion, lowering dietary PS with an increase in cholesterol level in commercial IF may support efficient absorption of dietary cholesterol, while maintaining low cholesterol synthesis levels. These results are anticipated to help manufacturing industries in proper formulation of infant food to achieve a closer dietary benefit found in infants consuming human milk.
Advisors/Committee Members: Jones, Peter (Food and Human Nutritional Science) (supervisor), Beta, Trust (Food and Human Nutritional Science) Moghadasian, Mohammed (Food and Human Nutritional Science) (examiningcommittee).
Subjects/Keywords: Phytosterols; Cholesterol; Infant formula
…57
viii
LIST OF FIGURES
Figure 1 Structure of cholesterol and some phytosterols… …REVIEW
1.1
Introduction
It has long been established that consumption of phytosterols (… …infancy.
4
Figure 1 Structure of cholesterol and some phytosterols
http://watcut.uwaterloo.ca… …phytosterol effect on cholesterol concentrations
Abbreviations: PS-Phytosterols, DMI- Dry matter… …do formula fed infants (37,57).
Phytosterols (PS) inhibit cholesterol…
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APA (6th Edition):
Babawale, E. (2018). The effects of dietary phytosterol and cholesterol concentration in infant formula on circulating cholesterol levels, cholesterol absorption and synthesis as well as other health biomarkers using neonate piglets. (Masters Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/32870
Chicago Manual of Style (16th Edition):
Babawale, Elizabeth. “The effects of dietary phytosterol and cholesterol concentration in infant formula on circulating cholesterol levels, cholesterol absorption and synthesis as well as other health biomarkers using neonate piglets.” 2018. Masters Thesis, University of Manitoba. Accessed January 18, 2021.
http://hdl.handle.net/1993/32870.
MLA Handbook (7th Edition):
Babawale, Elizabeth. “The effects of dietary phytosterol and cholesterol concentration in infant formula on circulating cholesterol levels, cholesterol absorption and synthesis as well as other health biomarkers using neonate piglets.” 2018. Web. 18 Jan 2021.
Vancouver:
Babawale E. The effects of dietary phytosterol and cholesterol concentration in infant formula on circulating cholesterol levels, cholesterol absorption and synthesis as well as other health biomarkers using neonate piglets. [Internet] [Masters thesis]. University of Manitoba; 2018. [cited 2021 Jan 18].
Available from: http://hdl.handle.net/1993/32870.
Council of Science Editors:
Babawale E. The effects of dietary phytosterol and cholesterol concentration in infant formula on circulating cholesterol levels, cholesterol absorption and synthesis as well as other health biomarkers using neonate piglets. [Masters Thesis]. University of Manitoba; 2018. Available from: http://hdl.handle.net/1993/32870
15.
Zychowski, Lisa.
Effect of phytosterol enrichment on the crystallisation, physiochemical, and interfacial behaviour of bulk and emulsified milk fat triacylglycerol matrices.
Degree: 2018, University College Cork
URL: http://hdl.handle.net/10468/5466
► Phytosterols possess the ability to significantly lower levels of low-density lipoprotein (LDL) cholesterol in the blood, but their bioaccessibility is dependent upon the solubility of…
(more)
▼ Phytosterols possess the ability to significantly lower levels of low-density lipoprotein (LDL) cholesterol in the blood, but their bioaccessibility is dependent upon the solubility of the phytosterol in the consumable food or pharmaceutical product.
Phytosterols are one of the most commonly used groups of bioactive compounds in the functional food industry. However, very little research has examined how
phytosterols crystallise within food systems or how the physiochemical properties of the food system change upon phytosterol addition. The studies in this thesis investigated phytosterol addition in bulk and emulsified milk fat matrices, as dairy products are a common matrix for phytosterol enrichment. The main objectives of the thesis were to: (i) characterise the collective crystalline behaviour of both milk fat and
phytosterols; (ii) quantify how phytosterol enrichment influences the physiochemical properties of the food system; (iii) investigate how an oil-in-water (o/w) interface influences phytosterol and milk fat crystalline behaviour; and (iv) develop and assess the means by which phytosterol solubility could be improved in milk fat matrices. In both the emulsion and bulk milk systems employed, the level of phytosterol-enrichment in milk fat was either 0 (the control), 3, or 6%. In phytosterol-enriched emulsions, whey protein (1%) was employed as the emulsifier in emulsions with 10% oil and 89% water. During cooling,
phytosterols addition altered the nucleation temperature of emulsions, but no such effect was identified in bulk milk fat. During the crystallisation process, emulsified milk fat triacylglycerols (TAG) packing expanded upon phytosterol enrichment, which was observed as an increase in the triple-chain length (3L). In bulk milk fat, both doublechain length (2L) and 3L TAG packing was seen during cooling; the 3L spacing also increased with phytosterol enrichment, but no differences were seen in the 2L packing. These results suggest that
phytosterols can insert themselves into the milk fat TAG network during cooling; however, the overall polymorphic form did not change. After storage, the milk fat TAG network developed into more structured polymorphic forms, and
phytosterols were no longer found within the TAG packing.
Phytosterols were also found to be able to decrease the average size of droplets in an emulsion and participate in a synergistic interaction with whey protein at the emulsion interface. In addition, phytosterol enrichment was found to have no negative effect on the creaming behaviour of the emulsions. Phytosterol crystallisation was altered by the addition of low molecular weight surfactants, lecithin and monoacylglycerol (MAG), and by changing the average droplet size from 1.0 to 0.2 µm. Lecithin and MAG addition significantly decreased phytosterol crystallisation in the bulk form, but changes in phytosterol crystallisation behaviour in the emulsified form were mainly driven by the decrease in droplet size. The lecithin-containing emulsions with the smaller droplets, however, showed…
Advisors/Committee Members: O'Mahony, James, Kelly, Alan, Auty, Mark A. E., Teagasc.
Subjects/Keywords: β-sitosterol; Emulsion; Phytosterols; Milk fat; Functional foods; X-ray diffraction
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APA ·
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APA (6th Edition):
Zychowski, L. (2018). Effect of phytosterol enrichment on the crystallisation, physiochemical, and interfacial behaviour of bulk and emulsified milk fat triacylglycerol matrices. (Thesis). University College Cork. Retrieved from http://hdl.handle.net/10468/5466
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Zychowski, Lisa. “Effect of phytosterol enrichment on the crystallisation, physiochemical, and interfacial behaviour of bulk and emulsified milk fat triacylglycerol matrices.” 2018. Thesis, University College Cork. Accessed January 18, 2021.
http://hdl.handle.net/10468/5466.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Zychowski, Lisa. “Effect of phytosterol enrichment on the crystallisation, physiochemical, and interfacial behaviour of bulk and emulsified milk fat triacylglycerol matrices.” 2018. Web. 18 Jan 2021.
Vancouver:
Zychowski L. Effect of phytosterol enrichment on the crystallisation, physiochemical, and interfacial behaviour of bulk and emulsified milk fat triacylglycerol matrices. [Internet] [Thesis]. University College Cork; 2018. [cited 2021 Jan 18].
Available from: http://hdl.handle.net/10468/5466.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Zychowski L. Effect of phytosterol enrichment on the crystallisation, physiochemical, and interfacial behaviour of bulk and emulsified milk fat triacylglycerol matrices. [Thesis]. University College Cork; 2018. Available from: http://hdl.handle.net/10468/5466
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
16.
Roberta Sampaio Pinho.
Composição centesimal, tocois e fitosterois de sementes de cinco espécies ocorrentes em Pernambuco (Brasil).
Degree: 2010, Universidade Federal Rural de Pernambuco
URL: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1317
► This work carried out the chemical characterization, tocols and phytosterol contents from the seed oil of the species Barnebya harleyi and Diplopterys pubipetala(Malpighiaceae), Croton adamantinus…
(more)
▼ This work carried out the chemical characterization, tocols and phytosterol contents from the seed oil of the species Barnebya harleyi and Diplopterys pubipetala(Malpighiaceae), Croton adamantinus (Euphorbiaceae), Couroupita guianensis (Lecythidaceae) and Hippocratea volubilis (Celastraceae) which are found in Brazil. The centesimal composition of the seeds was carried out in accordance with the AOAC (2000) and the carbohydrate content + alimentary fiber was estimated by the difference of the other components, using the following equation: CC=100% - (% humidity + % proteins + % lipids + % ash). To make the analysis of the tocols and
phytosterols, the seed oils were extracted through the Soxhlet apparatus using n-hexane as solvent. The tocols were analyzed by with HPLC (High Performance Liquid Chromatography) and the components identified by compararison of the retention times and UV spectrum with HPLC patterns (α-, β-, γ- e δ- tocopherol and α-, β-, γ- e δ-tocotrienol). The sterol composition was evaluated by GC-FID according to the method of the NP EN ISO 12228 (1999). Patterns used identification was acquired of Sigma including cholestanol, cholesterol, campesterol, stigmasterol, β-sitosterol, β-sitostanol and betulin. The protein contents ranged from 9,6g/100 g H. volubilis to 30,5 g/100 g in D. pubipetala. The carbohydrate contents ranged from 14,6 g/100 g in Barnebya harleyi to 33,8 g/100 g in Croton adamantinus. The ash contents ranged from 7,78g/100 g in C. guianensis to 2,13 g/100 g in H. volubilis. The oil contents obtained from the seeds ranged from 35,5 g/100 g in C. guianensis to 49,9 g/100 g in H. volubilis. The total contents of tocols ranged from 25,1 mg/100 g in C. guianensis to 72,7 mg/100 g in B. harleyi. α-Tocopherol, γ-tocopherol and γ-tocotrienol were detected in all the oils from the species analyzed while δ-tocotrienol was detected only in the oil from B. harleyi. D. pubipetala was the species with the highest amount of αtocopherol (23 mg/100 g oil). C. adamantinus presented the highest quantity of γ-tocopherol (63,3 mg/100 g). Among the tocotrienols, γ-tocotrienol reached the highest value (5,0 mg/100 g oil) in B. harleyi, the only species analyzed containing tocols in the oil. The total contents of
phytosterols in the oil ranged from 79,81 mg/100 g in C. guianensis to 91,57 mg/100 g in the oil from C. adamantinus. Cholesterol was detected in small amounts in all analyzed species, ranging from 0,26 mg/100 g in C. guianensis to 0,90 mg/100 g in D.pubipetala. β-Sitosterol, campesterol, and 7-stigmastanol were the most representative
phytosterols in the five investigated species. Two non identified peaks after Δ7- avenasterol (TR-24,440 and TR-24,680) in the chromatogram of the oil of C. guianensis corresponded to 57mg/100 g of the sterol fraction. In addition to these compounds, the clerosterol and campestanol were found in all the samples in small quantities and Δ7- avenasterol, with exception of…
Advisors/Committee Members: Ana Lúcia Figueiredo Porto, Elcida de Lima Araújo, Maria Inês Sucupira Maciel, Suzene Izídio da Silva.
Subjects/Keywords: Tocois; Fitosterois; Composição química; Malpighiaceae; Euphorbiaceae; Lecythidaceae; BOTANICA; Tocols; Phytosterols; Chemical characterization
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APA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Pinho, R. S. (2010). Composição centesimal, tocois e fitosterois de sementes de cinco espécies ocorrentes em Pernambuco (Brasil). (Thesis). Universidade Federal Rural de Pernambuco. Retrieved from http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1317
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Pinho, Roberta Sampaio. “Composição centesimal, tocois e fitosterois de sementes de cinco espécies ocorrentes em Pernambuco (Brasil).” 2010. Thesis, Universidade Federal Rural de Pernambuco. Accessed January 18, 2021.
http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1317.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Pinho, Roberta Sampaio. “Composição centesimal, tocois e fitosterois de sementes de cinco espécies ocorrentes em Pernambuco (Brasil).” 2010. Web. 18 Jan 2021.
Vancouver:
Pinho RS. Composição centesimal, tocois e fitosterois de sementes de cinco espécies ocorrentes em Pernambuco (Brasil). [Internet] [Thesis]. Universidade Federal Rural de Pernambuco; 2010. [cited 2021 Jan 18].
Available from: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1317.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Pinho RS. Composição centesimal, tocois e fitosterois de sementes de cinco espécies ocorrentes em Pernambuco (Brasil). [Thesis]. Universidade Federal Rural de Pernambuco; 2010. Available from: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1317
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
17.
Roberta Sampaio Pinho.
Composição centesimal, tocois e fitosterois de sementes de cinco espécies ocorrentes em Pernambuco (Brasil).
Degree: 2010, Universidade Federal Rural de Pernambuco
URL: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1317
► This work carried out the chemical characterization, tocols and phytosterol contents from the seed oil of the species Barnebya harleyi and Diplopterys pubipetala(Malpighiaceae), Croton adamantinus…
(more)
▼ This work carried out the chemical characterization, tocols and phytosterol contents from the seed oil of the species Barnebya harleyi and Diplopterys pubipetala(Malpighiaceae), Croton adamantinus (Euphorbiaceae), Couroupita guianensis (Lecythidaceae) and Hippocratea volubilis (Celastraceae) which are found in Brazil. The centesimal composition of the seeds was carried out in accordance with the AOAC (2000) and the carbohydrate content + alimentary fiber was estimated by the difference of the other components, using the following equation: CC=100% - (% humidity + % proteins + % lipids + % ash). To make the analysis of the tocols and
phytosterols, the seed oils were extracted through the Soxhlet apparatus using n-hexane as solvent. The tocols were analyzed by with HPLC (High Performance Liquid Chromatography) and the components identified by compararison of the retention times and UV spectrum with HPLC patterns (α-, β-, γ- e δ- tocopherol and α-, β-, γ- e δ-tocotrienol). The sterol composition was evaluated by GC-FID according to the method of the NP EN ISO 12228 (1999). Patterns used identification was acquired of Sigma including cholestanol, cholesterol, campesterol, stigmasterol, β-sitosterol, β-sitostanol and betulin. The protein contents ranged from 9,6g/100 g H. volubilis to 30,5 g/100 g in D. pubipetala. The carbohydrate contents ranged from 14,6 g/100 g in Barnebya harleyi to 33,8 g/100 g in Croton adamantinus. The ash contents ranged from 7,78g/100 g in C. guianensis to 2,13 g/100 g in H. volubilis. The oil contents obtained from the seeds ranged from 35,5 g/100 g in C. guianensis to 49,9 g/100 g in H. volubilis. The total contents of tocols ranged from 25,1 mg/100 g in C. guianensis to 72,7 mg/100 g in B. harleyi. α-Tocopherol, γ-tocopherol and γ-tocotrienol were detected in all the oils from the species analyzed while δ-tocotrienol was detected only in the oil from B. harleyi. D. pubipetala was the species with the highest amount of αtocopherol (23 mg/100 g oil). C. adamantinus presented the highest quantity of γ-tocopherol (63,3 mg/100 g). Among the tocotrienols, γ-tocotrienol reached the highest value (5,0 mg/100 g oil) in B. harleyi, the only species analyzed containing tocols in the oil. The total contents of
phytosterols in the oil ranged from 79,81 mg/100 g in C. guianensis to 91,57 mg/100 g in the oil from C. adamantinus. Cholesterol was detected in small amounts in all analyzed species, ranging from 0,26 mg/100 g in C. guianensis to 0,90 mg/100 g in D.pubipetala. β-Sitosterol, campesterol, and 7-stigmastanol were the most representative
phytosterols in the five investigated species. Two non identified peaks after Δ7- avenasterol (TR-24,440 and TR-24,680) in the chromatogram of the oil of C. guianensis corresponded to 57mg/100 g of the sterol fraction. In addition to these compounds, the clerosterol and campestanol were found in all the samples in small quantities and Δ7- avenasterol, with exception of…
Advisors/Committee Members: Ana Lúcia Figueiredo Porto, Elcida de Lima Araújo, Maria Inês Sucupira Maciel, Suzene Izídio da Silva.
Subjects/Keywords: Tocois; Fitosterois; Composição química; Malpighiaceae; Euphorbiaceae; Lecythidaceae; BOTANICA; Tocols; Phytosterols; Chemical characterization
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Pinho, R. S. (2010). Composição centesimal, tocois e fitosterois de sementes de cinco espécies ocorrentes em Pernambuco (Brasil). (Thesis). Universidade Federal Rural de Pernambuco. Retrieved from http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1317
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Pinho, Roberta Sampaio. “Composição centesimal, tocois e fitosterois de sementes de cinco espécies ocorrentes em Pernambuco (Brasil).” 2010. Thesis, Universidade Federal Rural de Pernambuco. Accessed January 18, 2021.
http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1317.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Pinho, Roberta Sampaio. “Composição centesimal, tocois e fitosterois de sementes de cinco espécies ocorrentes em Pernambuco (Brasil).” 2010. Web. 18 Jan 2021.
Vancouver:
Pinho RS. Composição centesimal, tocois e fitosterois de sementes de cinco espécies ocorrentes em Pernambuco (Brasil). [Internet] [Thesis]. Universidade Federal Rural de Pernambuco; 2010. [cited 2021 Jan 18].
Available from: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1317.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Pinho RS. Composição centesimal, tocois e fitosterois de sementes de cinco espécies ocorrentes em Pernambuco (Brasil). [Thesis]. Universidade Federal Rural de Pernambuco; 2010. Available from: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1317
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
18.
Bombo, Renata de Paula Assis.
Ação dos fitoesteróis sobre lesão aterosclerótica em camundongos com ablação gênica do receptor de LDL.
Degree: PhD, Endocrinologia, 2014, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/5/5135/tde-29102014-143321/
;
► Introdução: Os fitoesteróis (FE) são reconhecidos por reduzirem a concentração plasmática de LDL-colesterol, sendo importantes coadjuvantes no tratamento da hipercolesterolemia moderada. Entretanto, estudos publicados recentemente…
(more)
▼ Introdução: Os fitoesteróis (FE) são reconhecidos por reduzirem a concentração plasmática de LDL-colesterol, sendo importantes coadjuvantes no tratamento da hipercolesterolemia moderada. Entretanto, estudos publicados recentemente demonstram resultados conflitantes em relação à eficiência dos FE na prevenção da aterosclerose. Além disso, algumas investigações evidenciaram que o aumento da concentração plasmática de FE está positivamente relacionado ao risco de desenvolvimento de aterosclerose. Com a finalidade de elucidar a sua ação sobre esses parâmetros, o objetivo deste estudo foi avaliar os efeitos da suplementação de FE no desenvolvimento da aterosclerose em camundongos com ablação gênica para o receptor de LDL (LDLr-KO). Métodos: Os animais foram alimentados durante 16 semanas, com dieta rica em gordura (40% do valor calórico total da dieta), suplementada (grupo FE; 2%, n=10) ou não (Controle; n=10) com FE. Foram avaliadas as concentrações plasmáticas e hepáticas de colesterol, triglicérides, FE (beta-sitosterol, campesterol e latosterol). Na aorta dos animais, determinaram-se as concentrações de colesterol total, colesterol livre e éster e FE, além do infiltrado de macrófagos e infiltrado de lípides. Nos macrófagos do peritôneo dos animais, os quais assemelham-se aos presentes na artéria, avaliou-se a expressão de RNA mensageiro dos genes envolvidos no efluxo e influxo de colesterol (ABCA1, ABCG1, LOX1 e CD36). Também determinou-se as concentrações de FE no intestino e baço dos animais. Resultados: Conforme esperado, o consumo de FE induziu elevação plasmática dos principais FE, campesterol e de beta-sitosterol, reduzindo a concentração de colesterol no plasma. Houve aumento nas concentrações hepáticas de triglicérides e FE, entretanto, não foram observadas diferenças entre os grupos nas expressões de RNA mensageiro de genes lipolíticos (CPT, PPAR alfa) e lipogênicos (SREBP1-c, MTP, LXR e PPAR gamma) no fígado. Não houve, também, alteração no SREBP2, gene relacionado à síntese de colesterol. O conteúdo de colesterol total na artéria foi menor nos animais do grupo FE, não diferindo entre as formas livre e éster. As concentrações de FE na artéria foram iguais entre os grupos. A área de lesão no grupo FE foi menor em relação ao grupo-controle. A suplementação com FE induziu redução na expressão de RNA mensageiro de ABCG1, não interferindo na expressão dos outros genes estudados na artéria. Conclusão: Os achados deste estudo demonstram que a elevação de FE no plasma não induziu o seu acúmulo na parede da artéria e preveniu o desenvolvimento da aterosclerose
Introduction: The plasma cholesterol-reducing effect of hytosterols (PS) is well recognized and they are considered important adjuncts in the treatment of moderate hypercholesterolemia. However, recent studies have shown conflicting results regarding the efficiency of PS in the prevention of atherosclerosis. In addition, some studies showed that the increase in plasma PS concentration is positively correlated to the risk of atherosclerosis. In order to…
Advisors/Committee Members: Lottenberg, Ana Maria Pita.
Subjects/Keywords: Aterosclerose; Atherosclerosis; Camundongos Knockout; Cholesterol; Colesterol; Diet; Dieta; Fitoesteróis; Hipercolesterolemia; Hypercholesterolemia; Knockout mice; Phytosterols
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Bombo, R. d. P. A. (2014). Ação dos fitoesteróis sobre lesão aterosclerótica em camundongos com ablação gênica do receptor de LDL. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/5/5135/tde-29102014-143321/ ;
Chicago Manual of Style (16th Edition):
Bombo, Renata de Paula Assis. “Ação dos fitoesteróis sobre lesão aterosclerótica em camundongos com ablação gênica do receptor de LDL.” 2014. Doctoral Dissertation, University of São Paulo. Accessed January 18, 2021.
http://www.teses.usp.br/teses/disponiveis/5/5135/tde-29102014-143321/ ;.
MLA Handbook (7th Edition):
Bombo, Renata de Paula Assis. “Ação dos fitoesteróis sobre lesão aterosclerótica em camundongos com ablação gênica do receptor de LDL.” 2014. Web. 18 Jan 2021.
Vancouver:
Bombo RdPA. Ação dos fitoesteróis sobre lesão aterosclerótica em camundongos com ablação gênica do receptor de LDL. [Internet] [Doctoral dissertation]. University of São Paulo; 2014. [cited 2021 Jan 18].
Available from: http://www.teses.usp.br/teses/disponiveis/5/5135/tde-29102014-143321/ ;.
Council of Science Editors:
Bombo RdPA. Ação dos fitoesteróis sobre lesão aterosclerótica em camundongos com ablação gênica do receptor de LDL. [Doctoral Dissertation]. University of São Paulo; 2014. Available from: http://www.teses.usp.br/teses/disponiveis/5/5135/tde-29102014-143321/ ;
19.
Claudine Maria Alves Feio.
A Euterpe oleracea (açaí) modifica o metabolismo de esteróis e atenua a aterosclerose induzida experimentalmente.
Degree: 2011, Universidade Federal de São Paulo
URL: http://www.bdtd.unifesp.br/tede//tde_busca/arquivo.php?codArquivo=2462
► Introducao: Euterpe oleracea (acai) e uma fruta da regiao amazonica, cuja composicao quimica pode ser benefica para individuos com aterosclerose. Nos hipotetizamos que o consumo…
(more)
▼ Introducao: Euterpe oleracea (acai) e uma fruta da regiao amazonica, cuja composicao quimica pode ser benefica para individuos com aterosclerose. Nos hipotetizamos que o consumo de Euterpe oleracea poderia reduzir o desenvolvimento da aterosclerose por uma reducao na absorcao e sintese de colesterol. Metodos: Coelhos machos Nova Zelandia foram alimentados com uma dieta enriquecida em colesterol (0.5%) por 12 semanas, quando foram aleatoriamente distribuidos para tratamento com Euterpe oleracea ou agua alem de dieta enriquecida em colesterol (0,05%) por 12 semanas adicionais. Fitosterois plasmaticos e desmosterol foram determinados por cromatografia liquida de alto desempenho e espectrometria de massa. As lesoes ateroscleroticas foram estimadas por planimetria computadorizada. Resultados: Ao sacrificio, os animais tratados com Euterpe oleracea tiveram menores niveis de colesterol total (p=0.03) e de colesterol nao-HDL (p=0.03) em comparacao aos controles. Estes animais tiveram menores areas de aterosclerose em suas aortas ((p=0.001) e menor relacao intima/media (p=0.002) em comparacao aos controles. Ao final do estudo, os valores plasmaticos de campesterol, À-sitosterol, e desmosterol nao diferiram entre os grupos. Entretanto, os animais tratados com Euterpe oleracea mostraram menores valores para as relacoes desmosterol/campesterol (p=0.026) e desmosterol/À-sitosterol (p=0.006) em comparacao aos controles. Conclusoes: Consumo do extrato de Euterpe oleracea marcadamente melhora o perfil lipidico e atenua a aterosclerose. Estes efeitos foram em parte relacionados a um melhor balanco entre sintese e absorcao de esterois.
Background: Euterpe oleracea (acai) is a fruit from the Amazon region, whose chemical composition may be beneficial for individuals with atherosclerosis. We hypothesized that consumption of Euterpe oleracea would reduce therosclerosis development by a decrease in cholesterol absorption and synthesis. Methods: Male New Zealand rabbits were fed a cholesterol-enriched diet (0.5%) for 12 weeks, when they were randomized to receive Euterpe oleracea extract or water plus a 0.05% cholesterol-enriched diet for additional 12 weeks. Plasma phytosterols and desmosterol were determined by ultra performance liquid chromatography and mass spectrometry. Atherosclerotic lesions were estimated by computerized planimetry. Results: At sacrifice, animals treated with Euterpe oleracea had lower levels of total cholesterol (p=0.03) and non-HDL-cholesterol (p=0.03) as compared to controls. These animals had smaller atherosclerotic plaque area in their aortas (p=0.001) and a smaller intima/media ratio (p=0.002) in comparison with controls. At the end of the study, campesterol, À-sitosterol, and desmosterol plasma levels did not differ between groups. However, animals treated with Euterpe oleracea showed lower values for the desmosterol/campesterol (p=0.026) and desmosterol/À-sitosterol (p=0.006) ratios as compared to controls. Conclusion: Consumption of Euterpe oleracea extract markedly improved the lipid profile and…
Advisors/Committee Members: Maria Cristina de Oliveira Izar, Silvia Saiuli Miki Ihara, Maria Teresa Nogueira Bombig, Andre Arpad Faludi, Hermes Toros Xavier, Eliete da Cunha Araújo, Francisco Antonio Helfenstein Fonseca.
Subjects/Keywords: Fitosteróis; CARDIOLOGIA; Euterpe oleracea; Atherosclerosis; Lipids; Desmosterol; Phytosterols; Euterpe olerácea; Aterosclerose; Lípides; Desmosterol
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APA (6th Edition):
Feio, C. M. A. (2011). A Euterpe oleracea (açaí) modifica o metabolismo de esteróis e atenua a aterosclerose induzida experimentalmente. (Thesis). Universidade Federal de São Paulo. Retrieved from http://www.bdtd.unifesp.br/tede//tde_busca/arquivo.php?codArquivo=2462
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Feio, Claudine Maria Alves. “A Euterpe oleracea (açaí) modifica o metabolismo de esteróis e atenua a aterosclerose induzida experimentalmente.” 2011. Thesis, Universidade Federal de São Paulo. Accessed January 18, 2021.
http://www.bdtd.unifesp.br/tede//tde_busca/arquivo.php?codArquivo=2462.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Feio, Claudine Maria Alves. “A Euterpe oleracea (açaí) modifica o metabolismo de esteróis e atenua a aterosclerose induzida experimentalmente.” 2011. Web. 18 Jan 2021.
Vancouver:
Feio CMA. A Euterpe oleracea (açaí) modifica o metabolismo de esteróis e atenua a aterosclerose induzida experimentalmente. [Internet] [Thesis]. Universidade Federal de São Paulo; 2011. [cited 2021 Jan 18].
Available from: http://www.bdtd.unifesp.br/tede//tde_busca/arquivo.php?codArquivo=2462.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Feio CMA. A Euterpe oleracea (açaí) modifica o metabolismo de esteróis e atenua a aterosclerose induzida experimentalmente. [Thesis]. Universidade Federal de São Paulo; 2011. Available from: http://www.bdtd.unifesp.br/tede//tde_busca/arquivo.php?codArquivo=2462
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of the Western Cape
20.
Duba, Nandipha.
Investigation of the link between drought-induced changes in the expression of a novel sterol biosynthesis gene and drought tolerance in soybean
.
Degree: 2017, University of the Western Cape
URL: http://hdl.handle.net/11394/6338
► Glycine max (soybean) is an important crop species globally as it is used as a protein-rich food and feed crop and as a source of…
(more)
▼ Glycine max (soybean) is an important crop species globally as it is used as a protein-rich food
and feed crop and as a source of oils used in the food and biofuel industry. However, the
growth and yield of soybean is adversely affected by drought. Exposure of soybean to drought
leads to accumulation of reactive oxygen species (ROS) and cell membrane instability. Sterols
are membrane components that regulates membrane fluidity and permeability. Besides being
major components of the cell membranes, sterols such as lanosterol appear to play a role in
the regulation of ROS scavenging and some are precursors to brassinosteroids that act as
signaling molecules with hormonal function that regulate growth, development and
responses to abiotic stresses such as drought and salinity. In this study, the involvement of
plant sterols, also known as
phytosterols, in the regulation of soybean responses to drought
stress was investigated in Glycine max by determining the effects of drought on the
expression of a candidate lanosterol synthase gene (Glyma08g24160) and the content of a
subset of
phytosterols in soybean. The effects of inhibition of sterol synthesis on ROS
production and on superoxide dismutase (SOD), ascorbate peroxidase (APX), catalase (CAT)
and dehydroascorbate reductase (DHAR) were investigated. The concentration of hydrogen
peroxide (H2O2) as well as superoxide (O2-) increased in response to drought and sterol
synthesis inhibition, however, O2- concentration and sterol contents declined under drought
stress and sterol synthesis inhibition.
Advisors/Committee Members: Ludidi, Ndiko (advisor).
Subjects/Keywords: Glycine max;
Reactive oxygen species;
Lanosterol synthase;
Drought stress;
Antioxidant enzyme activity;
Phytosterols
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APA ·
Chicago ·
MLA ·
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CSE |
Export
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Manager
APA (6th Edition):
Duba, N. (2017). Investigation of the link between drought-induced changes in the expression of a novel sterol biosynthesis gene and drought tolerance in soybean
. (Thesis). University of the Western Cape. Retrieved from http://hdl.handle.net/11394/6338
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Duba, Nandipha. “Investigation of the link between drought-induced changes in the expression of a novel sterol biosynthesis gene and drought tolerance in soybean
.” 2017. Thesis, University of the Western Cape. Accessed January 18, 2021.
http://hdl.handle.net/11394/6338.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Duba, Nandipha. “Investigation of the link between drought-induced changes in the expression of a novel sterol biosynthesis gene and drought tolerance in soybean
.” 2017. Web. 18 Jan 2021.
Vancouver:
Duba N. Investigation of the link between drought-induced changes in the expression of a novel sterol biosynthesis gene and drought tolerance in soybean
. [Internet] [Thesis]. University of the Western Cape; 2017. [cited 2021 Jan 18].
Available from: http://hdl.handle.net/11394/6338.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Duba N. Investigation of the link between drought-induced changes in the expression of a novel sterol biosynthesis gene and drought tolerance in soybean
. [Thesis]. University of the Western Cape; 2017. Available from: http://hdl.handle.net/11394/6338
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Univerzitet u Beogradu
21.
Bogdanović, Aleksandra M., 1987-.
Dobijanje, karakterizacija i optimizacija hipolipemijskih
ekstrakata matičnjaka (Melissa officinalis) i grčkog semena
(Trigonella foenum-graecum) natkritičnim ugljenik
(IV)-oksidom.
Degree: Tehnološko-metalurški fakultet, 2017, Univerzitet u Beogradu
URL: https://fedorabg.bg.ac.rs/fedora/get/o:14730/bdef:Content/get
► Hemijske nauke - Hemija / Chemical Science - Chemistry
Sintetski hipolipemici danas se sve više zamenjuju prirodnim hipolipemicima, usled utvrđenih nedostataka, nus-pojava i sporednih efekata…
(more)
▼ Hemijske nauke - Hemija / Chemical Science -
Chemistry
Sintetski hipolipemici danas se sve više zamenjuju
prirodnim hipolipemicima, usled utvrđenih nedostataka, nus-pojava i
sporednih efekata sintetičkih lekova. Shodno tome, podstaknuta je
povećana upotreba biljaka, odnosno njihovih aktivnih komponenata-
sa hipolipemijskom aktivnošću. Zamena sintetskih jedinjenja
prirodnim aktivnim komponentama usmerava istraživanja u pravcu
ispitivanja različitih biljnih materijala i identifikovanja novih
jedinjenja sa hipolipemijskim dejstvom koji se mogu iz njih
izolovati. Zbog toga se veliki napori ulože u cilju dobijanja i
izolovanja prirodnih hipolipemika, kao i za razvoj efikasnih i
selektivnih tehnika ekstrakcije. Ekstrakciju konvencionalnim
rastvaračima karakterišu niska selektivnost i visoke temperature,
što može dovesti do degradacije željenih jedinjenja. Primenom
natkritične ekstrakcije (NKE) koja se odvija na nižim
temperaturama, sprečava se degradacija jedinjenja i dobija na
kvalitetu ekstrakata shodno većoj koncentraciji komponenata sa
željenim farmakološkim dejstvom. NKE je mnogo selektivnija od
konvencionalnih načina ekstrakcije. Selektivnost prema pojedinim
grupama jedinjenja se postiže podešavanjem uslova ekstrakcije
(temperature i pritiska). Usled lake i potpune separacije
natkritičnog fluida smanjenjem pritiska, ovaj vid ekstrakcije
omogućava dobijanje ekstrakata bez tragova rastvarača (npr. za
primenu u prehrambenoj, kozmetičkoj i farmaceutskoj industriji).
Cilj ovog rada je bilo proučavanje frakcija ekstrakata matičnjaka
(Melissae officinalis L., Lamiaceae) i grčkog semena (Trigonella
foenum-graecum L., Fabaceae) bogatih supstancama sa hipolipemijskom
aktivnosti, izolovanih primenom različitih metoda ekstrakcije, kao
i optimizacija procesa njihovog dobijanja. Za dobijanje ekstrakata
bogatih supstancama sa hipolipemijskim dejstvom, primenjena je
subkritična (SKE) i NKE sa ugljenik (IV)-oksidom, hidrodestilacija
i ekstrakcija etanolom. Na osnovu hemijskog profila dobijenih
ekstrakata, identifikovane su supstance koje su u literaturi
okarakterisane kao nosioci hipolipemijske aktivnosti i određivan je
njihov sadržaj. Za identifikaciju i kvantifikaciju aktivnih
komponenti u dobijenim ekstraktima korišćene su gasna
hromatografija sa masenom spektrometrijom (GC/MS) i tečna
hromatografije (HPLC). Cilj disertacije je bio ispitivanje kinetike
izolacije ekstrakata bogatih komponenatama nosiocima
hipolipemijskog dejstva, kao i analizi i optimizaciji različitih
procesa ekstrakcije, pri čemu je glavni naglasak dat analizi
kinetike procesa NKE, ispitivanjem uticaja variranja procesnih
parametara (pritiska i temperature) subkritične i NKE i
odgovarajućeg predtretmana biljnog materijala na prinos totalnog
ekstrakta i u njemu sadržaj komponenata nosilaca hipolipemijskog
dejstva...
Advisors/Committee Members: Petrović, Slobodan, 1950-.
Subjects/Keywords: Melissae officinalis; Trigonela foenum-graecum;
supercritical extraction; characterization; optimization;
polyphenols; diosgenin; phytosterols; antioxidants;
hypolipemics
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Bogdanović, Aleksandra M., 1. (2017). Dobijanje, karakterizacija i optimizacija hipolipemijskih
ekstrakata matičnjaka (Melissa officinalis) i grčkog semena
(Trigonella foenum-graecum) natkritičnim ugljenik
(IV)-oksidom. (Thesis). Univerzitet u Beogradu. Retrieved from https://fedorabg.bg.ac.rs/fedora/get/o:14730/bdef:Content/get
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Bogdanović, Aleksandra M., 1987-. “Dobijanje, karakterizacija i optimizacija hipolipemijskih
ekstrakata matičnjaka (Melissa officinalis) i grčkog semena
(Trigonella foenum-graecum) natkritičnim ugljenik
(IV)-oksidom.” 2017. Thesis, Univerzitet u Beogradu. Accessed January 18, 2021.
https://fedorabg.bg.ac.rs/fedora/get/o:14730/bdef:Content/get.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Bogdanović, Aleksandra M., 1987-. “Dobijanje, karakterizacija i optimizacija hipolipemijskih
ekstrakata matičnjaka (Melissa officinalis) i grčkog semena
(Trigonella foenum-graecum) natkritičnim ugljenik
(IV)-oksidom.” 2017. Web. 18 Jan 2021.
Vancouver:
Bogdanović, Aleksandra M. 1. Dobijanje, karakterizacija i optimizacija hipolipemijskih
ekstrakata matičnjaka (Melissa officinalis) i grčkog semena
(Trigonella foenum-graecum) natkritičnim ugljenik
(IV)-oksidom. [Internet] [Thesis]. Univerzitet u Beogradu; 2017. [cited 2021 Jan 18].
Available from: https://fedorabg.bg.ac.rs/fedora/get/o:14730/bdef:Content/get.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Bogdanović, Aleksandra M. 1. Dobijanje, karakterizacija i optimizacija hipolipemijskih
ekstrakata matičnjaka (Melissa officinalis) i grčkog semena
(Trigonella foenum-graecum) natkritičnim ugljenik
(IV)-oksidom. [Thesis]. Univerzitet u Beogradu; 2017. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:14730/bdef:Content/get
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
22.
Miguel, Ana Carolina Moron Gagliardi.
Efeitos da suplementação de manteiga e margarinas no metabolismo lipídico e inflamação de portadores de síndrome metabólica que mantiveram seus hábitos usuais de vida.
Degree: PhD, Cardiologia, 2010, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/5/5131/tde-19032010-112343/
;
► Introdução: O consumo de manteigas e margarinas faz parte do hábito alimentar da população e é uma forma eficaz de suplementação de ácidos graxos. No…
(more)
▼ Introdução: O consumo de manteigas e margarinas faz parte do hábito alimentar da população e é uma forma eficaz de suplementação de ácidos graxos. No entanto, até o momento se desconhece os efeitos de ácidos graxos saturados, trans, monoinsaturados, poliinsaturados e de fitosteróis no perfil lipídico, inflamatório, de marcadores de disfunção endotelial e no metabolismo da HDL em indivíduos com síndrome metabólica (SM). Objetivo: Examinar os efeitos do consumo diário de manteiga, margarina com ácido graxo trans, margarina com fitosterol e margarina sem ácido graxo trans, em quantidades recomendadas por diretrizes, sobre: 1) o perfil lipídico, apolipoproteínas (Apo), marcadores inflamatórios e de disfunção endotelial e transferência de lipídeos para HDL, em indivíduos com SM, sem alterar seus hábitos usuais de vida, 2) a associação desses parâmetros com a composição nutricional das dietas dos indivíduos estudados. Métodos: Este estudo foi randomizado, cego, onde 100 indivíduos receberam porções diárias isocalóricas de manteiga ou margarina com ácido graxo trans ou margarina com fitosterol ou margarina sem ácido graxo trans em adição às suas dietas usuais, por 5 semanas. Foram determinados: perfil lipídico, Apos, marcadores inflamatórios e de disfunção endotelial, LDL pequenas e densas e transferências de lipídeos para a HDL. Diferenças entre os grupos foram avaliados por ANOVA. Resultados: A amostra final foi composta por 66 indivíduos (63,6% mulheres, idade média 47,6 anos). Houve redução de -10,3% na Apo B (p=0,043) e de -15,2% na razão Apo B/Apo A-I (p=0,034) após consumo de margarina com fitosterol. Não foram verificadas diferenças significativas nos lípides após consumo de manteiga, margarina com trans ou margarina sem trans. Transferências de fosfolípides foram reduzidas no grupo margarina com fitosterol (-4,7% vs. margarina com trans p=0,037); no grupo margarina sem trans foram reduzidas as transferências de: colesterol éster (-27% vs. manteiga e margarina com trans p=0,002), triglicérides (-43,3% vs. outros grupos p<0,001) e colesterol livre (-16,4%, vs. margarina com trans e margarina com fitosterol p=0,006). Não foram verificadas alterações significantes nos marcadores inflamatórios e de disfunção endotelial entre os grupos. Associações foram observadas entre os marcadores inflamatórios e de disfunção endotelial e consumo de lipídeos totais, ácidos graxos saturados, mono e poliinsaturados, colesterol, além de consumo energético e de carboidratos. As transferências de lipídeos para HDL associaram-se inversamente com o consumo de fibra alimentar. Conclusão: Nossos resultados indicam que o consumo de manteiga, margarina com ácido graxo trans e margarina sem ácido graxo trans, nas quantidades estudadas, por indivíduos com síndrome metabólica que não alteraram seus hábitos usuais de vida, não modificam o perfil lipídico ou marcadores inflamatórios e de disfunção endotelial. O consumo de margarina com fitosterol e margarina sem trans nas quantidades recomendadas reduziram respectivamente a concentração de Apo B e a…
Advisors/Committee Members: Santos Filho, Raul Dias dos.
Subjects/Keywords: Dietary fats; Fitosteróis; Gorduras na dieta; Inflamação; Inflammation; Lipid metabolism; Metabolic syndrome X; Metabolismo dos lipídeos; Phytosterols; Síndrome X metabólica
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APA ·
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APA (6th Edition):
Miguel, A. C. M. G. (2010). Efeitos da suplementação de manteiga e margarinas no metabolismo lipídico e inflamação de portadores de síndrome metabólica que mantiveram seus hábitos usuais de vida. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/5/5131/tde-19032010-112343/ ;
Chicago Manual of Style (16th Edition):
Miguel, Ana Carolina Moron Gagliardi. “Efeitos da suplementação de manteiga e margarinas no metabolismo lipídico e inflamação de portadores de síndrome metabólica que mantiveram seus hábitos usuais de vida.” 2010. Doctoral Dissertation, University of São Paulo. Accessed January 18, 2021.
http://www.teses.usp.br/teses/disponiveis/5/5131/tde-19032010-112343/ ;.
MLA Handbook (7th Edition):
Miguel, Ana Carolina Moron Gagliardi. “Efeitos da suplementação de manteiga e margarinas no metabolismo lipídico e inflamação de portadores de síndrome metabólica que mantiveram seus hábitos usuais de vida.” 2010. Web. 18 Jan 2021.
Vancouver:
Miguel ACMG. Efeitos da suplementação de manteiga e margarinas no metabolismo lipídico e inflamação de portadores de síndrome metabólica que mantiveram seus hábitos usuais de vida. [Internet] [Doctoral dissertation]. University of São Paulo; 2010. [cited 2021 Jan 18].
Available from: http://www.teses.usp.br/teses/disponiveis/5/5131/tde-19032010-112343/ ;.
Council of Science Editors:
Miguel ACMG. Efeitos da suplementação de manteiga e margarinas no metabolismo lipídico e inflamação de portadores de síndrome metabólica que mantiveram seus hábitos usuais de vida. [Doctoral Dissertation]. University of São Paulo; 2010. Available from: http://www.teses.usp.br/teses/disponiveis/5/5131/tde-19032010-112343/ ;
Universidade Estadual de Campinas
23.
Marques, Anne y Castro.
Avaliação dos possíveis efeitos sinérgicos de ácido linoleico conjugado (CLA) e fitosterois na regulação de parâmetros metabólicos em camundongos : Evaluation of possible synergic effects of conjugated linoleic acid (CLA) and phytosterols in regulation of metabolic parameters in mice: Evaluation of possible synergic effects of conjugated linoleic acid (CLA) and phytosterols in regulation of metabolic parameters in mice.
Degree: 2013, Universidade Estadual de Campinas
URL: http://repositorio.unicamp.br/jspui/handle/REPOSIP/255070
► Abstract: The changes in the population lifestyle, such as bad eating habits and more sedentarism, led to increased prevalence of chronic diseases, including obesity. Various…
(more)
▼ Abstract: The changes in the population lifestyle, such as bad eating habits and more sedentarism, led to increased prevalence of chronic diseases, including obesity. Various compounds have been investigated in order to control this major public health problem. Conjugated linoleic acid (CLA), a family of isomers of linoleic acid, has various positive biological functions, such as anticarcinogenic, immunomodulatory and energy balance and body composition regulations. Despite the potential in reducing body weight, CLA also has adverse biological effects (insulin resistance and increased fat oxidation), which limit it use.
Phytosterols, lipids found in vegetable foods, reduce serum cholesterol levels, inflammation and cardiovascular disease risk. CLA and
phytosterols are related to substances with proven biological effect. It is possible that the interaction between then improves and/or enhance these effects. This study aimed to investigate the action of these compounds in the prevention of obesity induced by high-fat diet. Forty male Swiss mice received a high-fat diet supplemented with CLA and/or
phytosterols, at a concentration of 2%, for nine weeks. Energy intake, weight gain, body composition, serum lipid profile (total cholesterol, HDLcholesterol, triglycerides and free fatty acids), serum leptin, glucose and insulin tolerance tests, insulin pathway in liver and adipose tissue (Akt, FoxO and JAK-2 proteins), inflammation in liver, adipose tissue and hypothalamus (JNK, IL-1?, IL-6, IL-10 and TNF-?), and modulation of peroxisomal proliferator activated receptors (PPARs) ? and ? in liver, adipose tissue and hypothalamus were assessed. Parametric data were subjected to analysis of variance (ANOVA) and nonparametric data were analyzed by Kruskal-Wallis test. When applicable (p <0.05) were performed its post-hoc tests (Tukey or Dunns). Concomitant supplementation of
phytosterols and CLA did not alter energy intake, but significantly reduced weight gain, and increased lean mass and minerals concentration. Fat mass, serum leptin and PPARs, in liver and adipose tissue, were reduced in the animals. In CLA plus
phytosterols group there was no change in lipid profile. Although the animals have developed insulin resistance, the use of CLA plus
phytosterols showed a synergistic effect, with reduction in hepatic inflammation and improvement in the insulin pathway in liver and adipose tissue, compared to the obese group. CLA and
phytosterols supplementation reduced, in mice, the damage caused by the intake of high-fat diet, however, more studies are needed to understand the mechanisms of action and define the best doses
Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS (CRUESP), Maróstica Junior, Mário Roberto, 1980- (advisor), Junior, Mario Roberto Marostica (advisor), Universidade Estadual de Campinas. Faculdade de Engenharia de Alimentos (institution), Programa de Pós-Graduação em Alimentos e Nutrição (nameofprogram), Ming, Chiu Chih (committee member), Cintra, Dennys Esper (committee member), Domene, Semiramis Martins Alvares (committee member), Marquez, Ursula Maria Lanfer (committee member).
Subjects/Keywords: Acido linoleico conjugado; Fitosterois; Obesidade; Resistência à insulina; Inflamação; Conjugated linoleic acid; Phytosterols; Obesity; Insulin resistance; Inflammation
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APA (6th Edition):
Marques, A. y. C. (2013). Avaliação dos possíveis efeitos sinérgicos de ácido linoleico conjugado (CLA) e fitosterois na regulação de parâmetros metabólicos em camundongos : Evaluation of possible synergic effects of conjugated linoleic acid (CLA) and phytosterols in regulation of metabolic parameters in mice: Evaluation of possible synergic effects of conjugated linoleic acid (CLA) and phytosterols in regulation of metabolic parameters in mice. (Thesis). Universidade Estadual de Campinas. Retrieved from http://repositorio.unicamp.br/jspui/handle/REPOSIP/255070
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Marques, Anne y Castro. “Avaliação dos possíveis efeitos sinérgicos de ácido linoleico conjugado (CLA) e fitosterois na regulação de parâmetros metabólicos em camundongos : Evaluation of possible synergic effects of conjugated linoleic acid (CLA) and phytosterols in regulation of metabolic parameters in mice: Evaluation of possible synergic effects of conjugated linoleic acid (CLA) and phytosterols in regulation of metabolic parameters in mice.” 2013. Thesis, Universidade Estadual de Campinas. Accessed January 18, 2021.
http://repositorio.unicamp.br/jspui/handle/REPOSIP/255070.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Marques, Anne y Castro. “Avaliação dos possíveis efeitos sinérgicos de ácido linoleico conjugado (CLA) e fitosterois na regulação de parâmetros metabólicos em camundongos : Evaluation of possible synergic effects of conjugated linoleic acid (CLA) and phytosterols in regulation of metabolic parameters in mice: Evaluation of possible synergic effects of conjugated linoleic acid (CLA) and phytosterols in regulation of metabolic parameters in mice.” 2013. Web. 18 Jan 2021.
Vancouver:
Marques AyC. Avaliação dos possíveis efeitos sinérgicos de ácido linoleico conjugado (CLA) e fitosterois na regulação de parâmetros metabólicos em camundongos : Evaluation of possible synergic effects of conjugated linoleic acid (CLA) and phytosterols in regulation of metabolic parameters in mice: Evaluation of possible synergic effects of conjugated linoleic acid (CLA) and phytosterols in regulation of metabolic parameters in mice. [Internet] [Thesis]. Universidade Estadual de Campinas; 2013. [cited 2021 Jan 18].
Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/255070.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Marques AyC. Avaliação dos possíveis efeitos sinérgicos de ácido linoleico conjugado (CLA) e fitosterois na regulação de parâmetros metabólicos em camundongos : Evaluation of possible synergic effects of conjugated linoleic acid (CLA) and phytosterols in regulation of metabolic parameters in mice: Evaluation of possible synergic effects of conjugated linoleic acid (CLA) and phytosterols in regulation of metabolic parameters in mice. [Thesis]. Universidade Estadual de Campinas; 2013. Available from: http://repositorio.unicamp.br/jspui/handle/REPOSIP/255070
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Universitat de Barcelona
24.
Burciaga Monge, Alma Delia.
Metabolismo de esteroles esterificados en plantas: implicación en el desarrollo y la respuesta a estrés.
Degree: 2020, Universitat de Barcelona
URL: http://hdl.handle.net/10803/668657
► Sterols are a family of triterpenoid compounds that occur as free form or conjugated like steryl esters, steryl glycosides and acylated steryl glycosides. Each plant…
(more)
▼ Sterols are a family of triterpenoid compounds that occur as free form or conjugated like steryl esters, steryl glycosides and acylated steryl glycosides. Each plant species has its own qualitative and quantitative profile of free and conjugated sterols, although the most abundant sterols in the different fractions are β-sitoesterol, stigmasterol and campesterol. Free sterols and their glycosylated derivatives are localized in cell membranes, mainly in the plasma membrane, where they act as key structural components involved in maintaining membrane fluidity and permeability. On the contrary, steryl esters accumulate in cytoplasmic lipid droplets, where they served as a reservoir of sterols that can be stored or mobilized depending on the cellular needs (excess or shortage) of free and glycosylated sterols in cell membranes.
The synthesis of steryl esters is catalyzed by sterol acyltransferases that are essencial players in maintaining sterol homeostasis in cell membranes. There is ample evidence that steryl esters levels undergo significant changes during plant tissues senescence and when plants face different type of stress, in spite of which the current knowledge about sterol acyltransferases in plants is still limited. Until very recently, two Arabidopsis sterol acyltransferases where the only plant sterol acyltransferases cloned and characterized, phospholipid:sterol acyltransferase (PSAT1) and acyl-CoA:sterol acyltransferase (ASAT1). Recently, in a previous work carried out in our research group, the tomato enzymes ASAT1 and PSAT1 (SlASAT1 and SlPSAT1) where indetified, cloned and preliminary characterized. Using this knowledge as background, in this PhD Thesis project, progress has been made in the study of the biological function of the plant sterol acyltransferases ASAT1 and PSAT1 using Arabidopsis thaliana and Solanum lycopersicum (cv Micro-Tom), paying special attention to the study of their function, and the role of steryl esters in plant growth, development and response to stress.
The results obtained by functional complementation of the Arabidopsis asat1-1 and psat1-2 mutants with SlPSAT1 and SlASAT1 have confirmed the different ability of these enzymes to esterify sterol end products and sterol precursors, respectively. Besides, in seeds and leaves of mutants with inactive SlPSAT1 (CR-psat1) generated using CRISPR/Cas9 genome editing system, there is a strong reduction in the content of steryl esters that correlates with a moderate increase in free sterol levels, while in leaves theres is also a decrease of the number of lipid droplets compared to the one observed in wild type leaves. These changes did not occur in the tomato mutant lines with inactive SlASAT1 (CR-asat1). Altogether these results provide further support to the proposal that SlPSAT1 participates more actively than SlASAT1 in the biosynthesis of steryl esters and free sterol homeostasis. Loss of function of SlASAT1 causes a delay of seed germination but has no effect on the final germination percentage. However, the inactivation of…
Advisors/Committee Members: Universitat de Barcelona. Facultat de Farmàcia i Ciències de l'Alimentació, [email protected] (authoremail), false (authoremailshow), Altabella Artigas, Teresa (director), Ferrer i Prats, Albert (director).
Subjects/Keywords: Fitosterols; Fitosteroles; Phytosterols; Esterificació; Esterificación; Esterification; Arabidopsis; Tomàquets; Tomates; Tomatoes; Estrès; Estrés; Stress; Ciències Experimentals i Matemàtiques; 577
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APA (6th Edition):
Burciaga Monge, A. D. (2020). Metabolismo de esteroles esterificados en plantas: implicación en el desarrollo y la respuesta a estrés. (Thesis). Universitat de Barcelona. Retrieved from http://hdl.handle.net/10803/668657
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Burciaga Monge, Alma Delia. “Metabolismo de esteroles esterificados en plantas: implicación en el desarrollo y la respuesta a estrés.” 2020. Thesis, Universitat de Barcelona. Accessed January 18, 2021.
http://hdl.handle.net/10803/668657.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Burciaga Monge, Alma Delia. “Metabolismo de esteroles esterificados en plantas: implicación en el desarrollo y la respuesta a estrés.” 2020. Web. 18 Jan 2021.
Vancouver:
Burciaga Monge AD. Metabolismo de esteroles esterificados en plantas: implicación en el desarrollo y la respuesta a estrés. [Internet] [Thesis]. Universitat de Barcelona; 2020. [cited 2021 Jan 18].
Available from: http://hdl.handle.net/10803/668657.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Burciaga Monge AD. Metabolismo de esteroles esterificados en plantas: implicación en el desarrollo y la respuesta a estrés. [Thesis]. Universitat de Barcelona; 2020. Available from: http://hdl.handle.net/10803/668657
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
25.
SOONG YEAN YEAN.
Characterization of polyphenols, phytosterols and tocopherols from longan (Dimocarpus longan Lour.) seed and mango (Mangifera indica L.) kernel.
Degree: 2005, National University of Singapore
URL: http://scholarbank.nus.edu.sg/handle/10635/14944
Subjects/Keywords: Longan seeds; mango kernels; phytochemicals; polyphenols; phytosterols; tocopherols
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APA (6th Edition):
YEAN, S. Y. (2005). Characterization of polyphenols, phytosterols and tocopherols from longan (Dimocarpus longan Lour.) seed and mango (Mangifera indica L.) kernel. (Thesis). National University of Singapore. Retrieved from http://scholarbank.nus.edu.sg/handle/10635/14944
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
YEAN, SOONG YEAN. “Characterization of polyphenols, phytosterols and tocopherols from longan (Dimocarpus longan Lour.) seed and mango (Mangifera indica L.) kernel.” 2005. Thesis, National University of Singapore. Accessed January 18, 2021.
http://scholarbank.nus.edu.sg/handle/10635/14944.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
YEAN, SOONG YEAN. “Characterization of polyphenols, phytosterols and tocopherols from longan (Dimocarpus longan Lour.) seed and mango (Mangifera indica L.) kernel.” 2005. Web. 18 Jan 2021.
Vancouver:
YEAN SY. Characterization of polyphenols, phytosterols and tocopherols from longan (Dimocarpus longan Lour.) seed and mango (Mangifera indica L.) kernel. [Internet] [Thesis]. National University of Singapore; 2005. [cited 2021 Jan 18].
Available from: http://scholarbank.nus.edu.sg/handle/10635/14944.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
YEAN SY. Characterization of polyphenols, phytosterols and tocopherols from longan (Dimocarpus longan Lour.) seed and mango (Mangifera indica L.) kernel. [Thesis]. National University of Singapore; 2005. Available from: http://scholarbank.nus.edu.sg/handle/10635/14944
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Georgia Tech
26.
Dykstra, Christine M.
Fate of phytosterols in pulp and paper wastewater treated in a simulated aerated stabilization basin.
Degree: MS, Civil and Environmental Engineering, 2014, Georgia Tech
URL: http://hdl.handle.net/1853/52209
► Phytosterols are steroid chemicals produced by plants for the purposes of membrane function and hormone production. Phytosterols can cause endocrine disruption in aquatic species at…
(more)
▼ Phytosterols are steroid chemicals produced by plants for the purposes of membrane function and hormone production.
Phytosterols can cause endocrine disruption in aquatic species at very low concentrations and are suspected of contributing to endocrine disruption linked to pulp and paper effluent. Wastewater from the pulp and paper industry is often treated biologically in aerated stabilization basins (ASBs) that expose
phytosterols to a range of redox zones. Phytosterol removal in ASBs varies and stigmasterol has even been shown to increase across the treatment system. Little is known about the microbial processes that occur within ASBs and their effect on phytosterol removal. The objective of this research was to assess the biotransformation potential of
phytosterols in a simulated ASB treatment system and to improve understanding of the processes that occur within the various redox zones and their impact on the removal of
phytosterols. To assess the biotransformation of
phytosterols under aerobic conditions, three assays were conducted using a stock aerobic culture fed with pulp and paper wastewater. The assays tested three conditions:
phytosterols present as a sole added carbon source,
phytosterols with dextrin as an added carbon source, and
phytosterols with ethanol as a solubilizing agent and added carbon source. Phytosterol biotransformation was found to be limited by low phytosterol solubility. When solubilized, phytosterol removal occurred in two phases: an initial near-linear removal, followed by accelerated removal during the culture's stationary stage, possibly due to the release of extracellular cholesterol oxidase. The anoxic and anaerobic biotransformation of
phytosterols was examined through a series of three semi-batch cultures maintained under nitrate-reducing, sulfate-reducing and fermentative/methanogenic conditions, all developed from stock cultures fed with pulp and paper wastewater. Phytosterol removal was significant in the nitrate-reducing culture, although microbial activity and phytosterol removal declined in later stages. Phytosterol removal was also observed in the sulfate-reducing culture, although there was a significant lag period before removal occurred. No phytosterol removal was observed in the fermentative/methanogenic culture. Phytosterol biotransformation was also examined in the context of a lab-scale ASB fed continuously with pulp and paper wastewater. The steady-state ASB effluent and sediment characteristics were examined over three hydraulic retention times (HRTs). Effluent quality was not significantly affected by a change in HRT but sediment characteristics were significantly affected and, at shorter HRTs,
phytosterols accumulated in the sediment. Wastewater bioassays demonstrated the release of
phytosterols during the breakdown of solids. This research improves the understanding of biological processes within ASBs and their effect on phytosterol removal.
Advisors/Committee Members: Banerjee, Sujit (advisor), Pavlostathis, Spyros G. (advisor), Huang, Ching-hua (committee member).
Subjects/Keywords: Phytosterols; Beta-sitosterol; Stigmasterol; Campesterol; Aerated stabilization basin; ASB; Lagoon; Pulp and paper; Aerobic biodegradation; Anoxic biodegradation; Anaerobic biodegradation; Cholesterol oxidase
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APA (6th Edition):
Dykstra, C. M. (2014). Fate of phytosterols in pulp and paper wastewater treated in a simulated aerated stabilization basin. (Masters Thesis). Georgia Tech. Retrieved from http://hdl.handle.net/1853/52209
Chicago Manual of Style (16th Edition):
Dykstra, Christine M. “Fate of phytosterols in pulp and paper wastewater treated in a simulated aerated stabilization basin.” 2014. Masters Thesis, Georgia Tech. Accessed January 18, 2021.
http://hdl.handle.net/1853/52209.
MLA Handbook (7th Edition):
Dykstra, Christine M. “Fate of phytosterols in pulp and paper wastewater treated in a simulated aerated stabilization basin.” 2014. Web. 18 Jan 2021.
Vancouver:
Dykstra CM. Fate of phytosterols in pulp and paper wastewater treated in a simulated aerated stabilization basin. [Internet] [Masters thesis]. Georgia Tech; 2014. [cited 2021 Jan 18].
Available from: http://hdl.handle.net/1853/52209.
Council of Science Editors:
Dykstra CM. Fate of phytosterols in pulp and paper wastewater treated in a simulated aerated stabilization basin. [Masters Thesis]. Georgia Tech; 2014. Available from: http://hdl.handle.net/1853/52209
Swedish University of Agricultural Sciences
27.
Ubhayasekera, S. J. Kumari A.
Sterols and oxysterols.
Degree: 2009, Swedish University of Agricultural Sciences
URL: http://pub.epsilon.slu.se/2066/
► The ingredients of animal feed formulation, especially the fatty sources, play a significant role in the production of high-quality food of animal origin. Industrial fat…
(more)
▼ The ingredients of animal feed formulation, especially the fatty sources, play a significant role in the production of high-quality food of animal origin. Industrial fat by-products are a major source of feeding fats in Europe. The main objectives of the project were firstly to assess feed fats and oils for their composition and content of sterols (cholesterol and phytosterols) and oxysterols, and secondly to assess the levels of cholesterol and oxycholesterols of chicken and rabbit tissues after feeding with especially formulated feeds containing trans fatty acids and oxidized lipids. The lack of standardized analytical procedure prompted the evaluation of an in-house purification method by comparing it with a number of commonly used methods for the analysis of oxysterols. The saponification and transesterification steps showed rather comparable results. A two-dimensional capillary GC column with different stationary phases (a 35% phenyl column coupled to an apolar 5% phenyl column) was used for better resolution of a large number of oxysterols. This new system improved the separation efficiency and reduced the analytical time for a wide range of oxysterols. The satisfactory purification method and the reliable separation of oxysterols facilitated the qualitative and quantitative assessment of sterols and oxysterols in samples of by-products from chemical and physical refining. A large variation in the levels of sterols and oxysterols was observed in the fat by-products from chemical and physical refining processes for edible fats and oils. The observed variations in the contents and composition of sterols and oxysterols were mainly due to the origins, production facility and different processing conditions of the by-product samples. The highly oxidized lipid and trans fatty acid feeds significantly increased the contents of cholesterol and oxycholesterols in edible parts, e.g. the muscles and livers of chickens and rabbits (0.01< p ≤0.05). Hence, the consumption of products from animals fed with higher levels of trans fatty acids and oxidized lipid feeds may contribute to higher ingestion of cholesterol and oxycholesterols by humans.
Subjects/Keywords: phytosterols; cholesterol; oxidation; feeds; fats; oils; fatty acids; lipids; foods; animal tissues; animal feeding; chicken; rabbits; analytical methods; Animal tissues; chicken; cholesterol; fat by-products; feed fats; oxycholesterols; oxyphytosterols; phytosterols; rabbit; two-dimensional capillary GC
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APA (6th Edition):
Ubhayasekera, S. J. K. A. (2009). Sterols and oxysterols. (Doctoral Dissertation). Swedish University of Agricultural Sciences. Retrieved from http://pub.epsilon.slu.se/2066/
Chicago Manual of Style (16th Edition):
Ubhayasekera, S J Kumari A. “Sterols and oxysterols.” 2009. Doctoral Dissertation, Swedish University of Agricultural Sciences. Accessed January 18, 2021.
http://pub.epsilon.slu.se/2066/.
MLA Handbook (7th Edition):
Ubhayasekera, S J Kumari A. “Sterols and oxysterols.” 2009. Web. 18 Jan 2021.
Vancouver:
Ubhayasekera SJKA. Sterols and oxysterols. [Internet] [Doctoral dissertation]. Swedish University of Agricultural Sciences; 2009. [cited 2021 Jan 18].
Available from: http://pub.epsilon.slu.se/2066/.
Council of Science Editors:
Ubhayasekera SJKA. Sterols and oxysterols. [Doctoral Dissertation]. Swedish University of Agricultural Sciences; 2009. Available from: http://pub.epsilon.slu.se/2066/
Swedish University of Agricultural Sciences
28.
Pettersson, Andreas.
Effects of replacing fish oil with vegetable oils in feed for rainbow trout (Oncorhynchus mykiss) and Arctic charr (Salvelinus alpinus).
Degree: 2010, Swedish University of Agricultural Sciences
URL: http://pub.epsilon.slu.se/2284/
► As global capture of fish has stagnated and fish consumption is increasing due to a growing human population, the demand can only be met by…
(more)
▼ As global capture of fish has stagnated and fish consumption is increasing due to a growing human population, the demand can only be met by increased aquaculture production. Fish oil (FO), derived exclusively from wild pelagic fish, has traditionally been used as the primary lipid source in fish feeds. For a number of reasons, more sustainable development of aquaculture is necessary where FO needs to be replaced with a more sustainable lipid source. This thesis investigated the effects of FO replacement with two vegetable oils on growth, lipid content, feed preference and swimming performance of two salmonid species; rainbow trout and Arctic charr. In addition, a comparison of lipid content and composition with wild fish was performed to highlight the importance of natural food webs for successful production of specific fish species. The results obtained showed no negative effects on growth of fish fed vegetable oils. However, significant changes in fatty acid profiles were observed in fish tissues, with reduced levels of long-chain polyunsaturated fatty acids (LCPUFA), mainly EPA and DHA, and increased levels of 18:1n-9 and 18:2n-6. Comparisons of fatty acid profiles of wild and farmed Arctic charr showed significant differences in individual n-3 and n-6 fatty acids. The largest difference was found in arachidonic acid (20:4n-6) content with 7-fold higher levels in the phospholipid fraction in white muscle of wild Arctic charr compared with Arctic charr fed marine FO. Cholesterol-lowering effects were observed in fish fed rapeseed oil, possibly explained by the presence of phytosterols in the diet. Swimming performance at 4 ºC was significantly reduced in Arctic charr fed a blend of rapeseed oil and palm oil. This outcome is suggested to be an effect of the different levels of n-3 LCPUFA and saturated fatty acids due to their temperature influenced properties. The results in this thesis imply that an appropriate mix of vegetable oils and FO can replace the sole use of FO in fish feeds. However, researchers and feed manufacturers should be encouraged to continue to increase feed diversification in order to optimize the nutritional requirements of farmed fish.
Subjects/Keywords: oncorhynchus mykiss; salvelinus alpinus; feeds; fish oils; rapeseed oil; palm oils; fish; lipid content; fatty acids; phytosterols; animal performance; salmonids; fish oil; vegetable oil; n-3 LCPUFA; phospholipid; DHA; arachidonic acid; swimming performance; phytosterols.
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APA (6th Edition):
Pettersson, A. (2010). Effects of replacing fish oil with vegetable oils in feed for rainbow trout (Oncorhynchus mykiss) and Arctic charr (Salvelinus alpinus). (Doctoral Dissertation). Swedish University of Agricultural Sciences. Retrieved from http://pub.epsilon.slu.se/2284/
Chicago Manual of Style (16th Edition):
Pettersson, Andreas. “Effects of replacing fish oil with vegetable oils in feed for rainbow trout (Oncorhynchus mykiss) and Arctic charr (Salvelinus alpinus).” 2010. Doctoral Dissertation, Swedish University of Agricultural Sciences. Accessed January 18, 2021.
http://pub.epsilon.slu.se/2284/.
MLA Handbook (7th Edition):
Pettersson, Andreas. “Effects of replacing fish oil with vegetable oils in feed for rainbow trout (Oncorhynchus mykiss) and Arctic charr (Salvelinus alpinus).” 2010. Web. 18 Jan 2021.
Vancouver:
Pettersson A. Effects of replacing fish oil with vegetable oils in feed for rainbow trout (Oncorhynchus mykiss) and Arctic charr (Salvelinus alpinus). [Internet] [Doctoral dissertation]. Swedish University of Agricultural Sciences; 2010. [cited 2021 Jan 18].
Available from: http://pub.epsilon.slu.se/2284/.
Council of Science Editors:
Pettersson A. Effects of replacing fish oil with vegetable oils in feed for rainbow trout (Oncorhynchus mykiss) and Arctic charr (Salvelinus alpinus). [Doctoral Dissertation]. Swedish University of Agricultural Sciences; 2010. Available from: http://pub.epsilon.slu.se/2284/
Swedish University of Agricultural Sciences
29.
Madawala, Samanthi R. P.
Novel lipid derivatives for health benefits.
Degree: 2013, Swedish University of Agricultural Sciences
URL: http://pub.epsilon.slu.se/10844/
► Obesity is a public health concern and requires effective management with multiple approaches. Dietary supplements of bioactive compounds that can improve fatty acid oxidation and…
(more)
▼ Obesity is a public health concern and requires effective management with multiple approaches. Dietary supplements of bioactive compounds that can improve fatty acid oxidation and thermogenesis are currently in focus to develop anti-obese food ingredients/nutraceuticals without side-effects. Dietary 1,3-diacylglycerol (DAG) and supplementation of α-lipoic acid (LA) have been shown to reduce fat accumulation and improve lipid profile while phytosterols (PS) are known for reducing blood cholesterol.
In this thesis, novel lipid derivatives of LA with PS and 1,3-DAG were synthesized based on the hypothesis, that they would possess advantages over the individual constituents in controlling obesity due to increased stability, solubility, and bioavailability. A mild esterification method was developed to synthesize conjugates of LA and its reduced form (DHLA), with PS and 1,3-DAG yielding 60-80% of the products. The novel DHLA derivatives showed higher in vitro free radical scavenging capacity than the corresponding LA derivatives, and were comparable to pure DHLA.
In a pilot in vitro study, LA derivative with 1,3-dilaurin (diLaLA) was completely hydrolyzed by pancreatic lipase, releasing monolipoate, C12:0 and LA. Free LA was detected in plasma 2 h after oral administration of diLaLA to mice. Effects of diLaLA on body weight and lipid metabolism were evaluated in male C57BL/6J diet-induced obese mice on a high fat diet (HFD) and a control treated only with vehicle. After oral administration of diLaLA at 10, 50 and 250 mg/kg body wt. daily for 6 weeks, body weight was lowered (p<0.05) in high dose group compared with the control and low dose groups. Treatment with high dose also reduced (p<0.05) plasma and hepatic free fatty acid contents, while the concentrations of blood glucose, total cholesterol, and liver triacylglycerol showed a reducing trend compared with the control. Stearoyl-CoA desaturase (SCD)-1 activity, estimated by SCD16 index (C16:1n-7/C16:0), showed lower activity (p<0.05) in white adipose tissues while some key genes involved in fatty acid β-oxidation in liver showed upregulation in the high dose group compared with the control. Oral treatment with diLaLA reduced HFD-induced obesity in mice, possibly through enhanced energy expenditure via β-oxidation and suppressing in vivo lipogenesis, suggesting its potential as a promising candidate against obesity.
Subjects/Keywords: lipoic acid; lipid metabolism; overweight; weight reduction; weight reduction diet; phytosterols; lauric acid; biosynthesis; mice; laboratory animals; Novel lipid derivatives; Body weight reduction; Lipid metabolism; Phytosterol derivatives; Lipoic acid; Diacylglycerol
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APA (6th Edition):
Madawala, S. R. P. (2013). Novel lipid derivatives for health benefits. (Doctoral Dissertation). Swedish University of Agricultural Sciences. Retrieved from http://pub.epsilon.slu.se/10844/
Chicago Manual of Style (16th Edition):
Madawala, Samanthi R P. “Novel lipid derivatives for health benefits.” 2013. Doctoral Dissertation, Swedish University of Agricultural Sciences. Accessed January 18, 2021.
http://pub.epsilon.slu.se/10844/.
MLA Handbook (7th Edition):
Madawala, Samanthi R P. “Novel lipid derivatives for health benefits.” 2013. Web. 18 Jan 2021.
Vancouver:
Madawala SRP. Novel lipid derivatives for health benefits. [Internet] [Doctoral dissertation]. Swedish University of Agricultural Sciences; 2013. [cited 2021 Jan 18].
Available from: http://pub.epsilon.slu.se/10844/.
Council of Science Editors:
Madawala SRP. Novel lipid derivatives for health benefits. [Doctoral Dissertation]. Swedish University of Agricultural Sciences; 2013. Available from: http://pub.epsilon.slu.se/10844/
30.
Grosjean, Kevin.
Microdomaines ordonnés de la membrane plasmique végétale : caractérisation et rôle dans la signalisation associée à la défense : Plant plasma membrane ordered domains : caracterization during defense signaling cascade.
Degree: Docteur es, Sciences de la Terre, 2015, Université de Bourgogne
URL: http://www.theses.fr/2015DIJOS089
► Au cours de ces dernières années, des études ont montré l’existence d’une compartimentation latéraledes composants de la membrane plasmique végétale, de manière analogue à ce…
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▼ Au cours de ces dernières années, des études ont montré l’existence d’une compartimentation latéraledes composants de la membrane plasmique végétale, de manière analogue à ce qui avait été montréchez les animaux et les levures. L’objectif de cette thèse était d’apporter de nouveaux éléments decaractérisation de cette compartimentation (propriétés physiques de domaines particuliers, mécanismesde mise en place de ces domaines, de contrôle de leur taille, etc…) et d’étudier son rôle dans laphysiologie de la cellule végétale.Le développement d’une méthodologie de microscopie confocale spectrale couplée à l’utilisationd’une sonde environnementale a permis d’apporter la première description à l'échellesubmicrométrique de l’organisation du plasmalemme en territoires aux propriétés physiquesdifférentiées. Ces domaines coexistent au sein de la membrane plasmique de cellules en suspension,comme à celle de membranes artificielles composées de lipides modèles ou de lipides de membranescellulaires, de vésicules géantes constituées de membrane plasmique purifiée, ou de protoplastes.Cependant, les différences de l’organisation latérale observées chez ces différentes membranes ontpermis de montrer l’importance des phytostérols qui seraient, par le biais d'interactions spécifiquesavec d’autres lipides végétaux tels que les GIPCs, des composés essentiels pour la formation locale dedomaines lipidiques ordonnés. La grande diversité des lipides végétaux organiserait ainsi lacompartimentation de la membrane plasmique permettant la ségrégation dynamique des composantsmembranaires. Si les stérols augmentent de manière importante le degré de compaction de la bicouche,les protéines le diminuent. Le cytosquelette et la paroi ne semblent, quant à eux, modifier ni laprésence, ni l’organisation des domaines ordonnés de la membrane plasmique. Nous avons égalementmontré que l’organisation de ces domaines évolue transitoirement lors des étapes précoces de lacascade de signalisation induite par des réactions de défense. De fait, nous avons identifié desmodifications des propriétés physiques globales et de l’organisation fine de la membrane provoquéespar différents éliciteurs de réactions de défense, dont la cryptogéine, une protéine sécrétée parl’oomycète Phytophthora cryptogea. Nous avons montré que ces modifications sont un élémentgénérique de la signalisation de défense, sous la dépendance de phénomènes de phosphorylation, leburst oxydatif étant également une étape clé de l’augmentation du degré d’ordre observé dans lesphases précoces de cette signalisation. La cryptogéine, qui présente une aptitude singulière pour piégerles stérols, a également montré une capacité spécifique à augmenter la fluidité membranaire, ceparamètre pouvant contrôler l’intensité de la cascade de signalisation, mesurée par la production deformes actives d’oxygène.Ces résultats ouvrent de nouvelles perspectives dans la compréhension des interactions cellule-élicitineet apportent un nouvel éclairage sur le rôle des lipides végétaux dans l’organisation latérale de lamembrane…
Advisors/Committee Members: Simon-Plas, Françoise (thesis director), Gerbeau-Pissot, Patricia (thesis director).
Subjects/Keywords: Cryptogéine; Tabac; Mécanismes de Défense; Di-4-ANEPPDHQ; Membrane Plasmique; Phytostérols; Lipides; Domaines ordonnés; Cryptogein; Tobacco; Defense Mechanisms; Di-4-ANEPPDHQ; Plasma Membrane; Phytosterols; Lipids; Ordered Domains; 550; 580
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APA (6th Edition):
Grosjean, K. (2015). Microdomaines ordonnés de la membrane plasmique végétale : caractérisation et rôle dans la signalisation associée à la défense : Plant plasma membrane ordered domains : caracterization during defense signaling cascade. (Doctoral Dissertation). Université de Bourgogne. Retrieved from http://www.theses.fr/2015DIJOS089
Chicago Manual of Style (16th Edition):
Grosjean, Kevin. “Microdomaines ordonnés de la membrane plasmique végétale : caractérisation et rôle dans la signalisation associée à la défense : Plant plasma membrane ordered domains : caracterization during defense signaling cascade.” 2015. Doctoral Dissertation, Université de Bourgogne. Accessed January 18, 2021.
http://www.theses.fr/2015DIJOS089.
MLA Handbook (7th Edition):
Grosjean, Kevin. “Microdomaines ordonnés de la membrane plasmique végétale : caractérisation et rôle dans la signalisation associée à la défense : Plant plasma membrane ordered domains : caracterization during defense signaling cascade.” 2015. Web. 18 Jan 2021.
Vancouver:
Grosjean K. Microdomaines ordonnés de la membrane plasmique végétale : caractérisation et rôle dans la signalisation associée à la défense : Plant plasma membrane ordered domains : caracterization during defense signaling cascade. [Internet] [Doctoral dissertation]. Université de Bourgogne; 2015. [cited 2021 Jan 18].
Available from: http://www.theses.fr/2015DIJOS089.
Council of Science Editors:
Grosjean K. Microdomaines ordonnés de la membrane plasmique végétale : caractérisation et rôle dans la signalisation associée à la défense : Plant plasma membrane ordered domains : caracterization during defense signaling cascade. [Doctoral Dissertation]. Université de Bourgogne; 2015. Available from: http://www.theses.fr/2015DIJOS089
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