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You searched for subject:(Pharmacological chaperones). Showing records 1 – 10 of 10 total matches.

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University of Miami

1. Morton, Terrell R. Increased Acetylcholinesterase Expression Through Pharmacological Chaperones.

Degree: MS, Neuroscience (Medicine), 2013, University of Miami

  Acetylcholinesterase (AChE) is the enzyme that functions in terminating neurotransmission by hydrolyzing acetylcholine (ACh) in the central and peripheral nervous systems. Like all exportable… (more)

Subjects/Keywords: Acetylcholinesterase; Pharmacological Chaperones; Donepezil; Acetylcholinesterase Inhibitors; Galantamine; Tacrine

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Morton, T. R. (2013). Increased Acetylcholinesterase Expression Through Pharmacological Chaperones. (Thesis). University of Miami. Retrieved from https://scholarlyrepository.miami.edu/oa_theses/443

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Morton, Terrell R. “Increased Acetylcholinesterase Expression Through Pharmacological Chaperones.” 2013. Thesis, University of Miami. Accessed January 17, 2021. https://scholarlyrepository.miami.edu/oa_theses/443.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Morton, Terrell R. “Increased Acetylcholinesterase Expression Through Pharmacological Chaperones.” 2013. Web. 17 Jan 2021.

Vancouver:

Morton TR. Increased Acetylcholinesterase Expression Through Pharmacological Chaperones. [Internet] [Thesis]. University of Miami; 2013. [cited 2021 Jan 17]. Available from: https://scholarlyrepository.miami.edu/oa_theses/443.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Morton TR. Increased Acetylcholinesterase Expression Through Pharmacological Chaperones. [Thesis]. University of Miami; 2013. Available from: https://scholarlyrepository.miami.edu/oa_theses/443

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Toronto

2. Beerepoot, Pieter Claus. Pharmacological Chaperones of the Dopamine Transporter: A Strategy for Increasing Function of Wild Type and Mutant Transporter.

Degree: PhD, 2017, University of Toronto

 The dopamine transporter (DAT) is a membrane protein that is essential for regulating signaling and intracellular stores of the neurotransmitter dopamine. An array of pathological… (more)

Subjects/Keywords: Dopamine; Dopamine transporter deficiency syndrome; Pharmacological chaperones; Protein folding; 0419

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APA (6th Edition):

Beerepoot, P. C. (2017). Pharmacological Chaperones of the Dopamine Transporter: A Strategy for Increasing Function of Wild Type and Mutant Transporter. (Doctoral Dissertation). University of Toronto. Retrieved from http://hdl.handle.net/1807/78039

Chicago Manual of Style (16th Edition):

Beerepoot, Pieter Claus. “Pharmacological Chaperones of the Dopamine Transporter: A Strategy for Increasing Function of Wild Type and Mutant Transporter.” 2017. Doctoral Dissertation, University of Toronto. Accessed January 17, 2021. http://hdl.handle.net/1807/78039.

MLA Handbook (7th Edition):

Beerepoot, Pieter Claus. “Pharmacological Chaperones of the Dopamine Transporter: A Strategy for Increasing Function of Wild Type and Mutant Transporter.” 2017. Web. 17 Jan 2021.

Vancouver:

Beerepoot PC. Pharmacological Chaperones of the Dopamine Transporter: A Strategy for Increasing Function of Wild Type and Mutant Transporter. [Internet] [Doctoral dissertation]. University of Toronto; 2017. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1807/78039.

Council of Science Editors:

Beerepoot PC. Pharmacological Chaperones of the Dopamine Transporter: A Strategy for Increasing Function of Wild Type and Mutant Transporter. [Doctoral Dissertation]. University of Toronto; 2017. Available from: http://hdl.handle.net/1807/78039

3. Guce, Abigail Ida. Structural and Mechanistic Studies of alpha-galactosidase A and Pharmacological Chaperones.

Degree: PhD, Chemistry, 2010, U of Massachusetts : PhD

  Human α-galactosidase (α-GAL; EC 3.2.1.22) is a lysosomal enzyme that hydrolyzes of terminal alpha-linked galactosyl residue of glycosphingolipids. Deficiencies in α-GAL leads to Fabry… (more)

Subjects/Keywords: Pharmacological chaperones; Galactosidase; Fabry disease; Lysosomal storage diseases; Chemistry

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APA (6th Edition):

Guce, A. I. (2010). Structural and Mechanistic Studies of alpha-galactosidase A and Pharmacological Chaperones. (Doctoral Dissertation). U of Massachusetts : PhD. Retrieved from https://scholarworks.umass.edu/open_access_dissertations/202

Chicago Manual of Style (16th Edition):

Guce, Abigail Ida. “Structural and Mechanistic Studies of alpha-galactosidase A and Pharmacological Chaperones.” 2010. Doctoral Dissertation, U of Massachusetts : PhD. Accessed January 17, 2021. https://scholarworks.umass.edu/open_access_dissertations/202.

MLA Handbook (7th Edition):

Guce, Abigail Ida. “Structural and Mechanistic Studies of alpha-galactosidase A and Pharmacological Chaperones.” 2010. Web. 17 Jan 2021.

Vancouver:

Guce AI. Structural and Mechanistic Studies of alpha-galactosidase A and Pharmacological Chaperones. [Internet] [Doctoral dissertation]. U of Massachusetts : PhD; 2010. [cited 2021 Jan 17]. Available from: https://scholarworks.umass.edu/open_access_dissertations/202.

Council of Science Editors:

Guce AI. Structural and Mechanistic Studies of alpha-galactosidase A and Pharmacological Chaperones. [Doctoral Dissertation]. U of Massachusetts : PhD; 2010. Available from: https://scholarworks.umass.edu/open_access_dissertations/202


Universidade de Lisboa

4. Costa, Ana Carolina Ramos. Distinct strategies to overcome severe forms of PKU: The p.G46S as a model to identify small molecules modulators of protein aggregation and evaluation of an enzyme replacement approach using a nanoparticulate system.

Degree: 2017, Universidade de Lisboa

Tese de mestrado, Ciências Biofarmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2017

This work explores distinct strategies to overcome phenylketonuria (PKU; OMIM 261600), the most… (more)

Subjects/Keywords: Inborn errors of metabolism; Phenylketonuria; Pharmacological Chaperones; Proteostasis Regulators; Chitosan Nanoparticles; Teses de mestrado - 2017; Ciências da Saúde

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APA (6th Edition):

Costa, A. C. R. (2017). Distinct strategies to overcome severe forms of PKU: The p.G46S as a model to identify small molecules modulators of protein aggregation and evaluation of an enzyme replacement approach using a nanoparticulate system. (Thesis). Universidade de Lisboa. Retrieved from https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/34293

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Costa, Ana Carolina Ramos. “Distinct strategies to overcome severe forms of PKU: The p.G46S as a model to identify small molecules modulators of protein aggregation and evaluation of an enzyme replacement approach using a nanoparticulate system.” 2017. Thesis, Universidade de Lisboa. Accessed January 17, 2021. https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/34293.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Costa, Ana Carolina Ramos. “Distinct strategies to overcome severe forms of PKU: The p.G46S as a model to identify small molecules modulators of protein aggregation and evaluation of an enzyme replacement approach using a nanoparticulate system.” 2017. Web. 17 Jan 2021.

Vancouver:

Costa ACR. Distinct strategies to overcome severe forms of PKU: The p.G46S as a model to identify small molecules modulators of protein aggregation and evaluation of an enzyme replacement approach using a nanoparticulate system. [Internet] [Thesis]. Universidade de Lisboa; 2017. [cited 2021 Jan 17]. Available from: https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/34293.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Costa ACR. Distinct strategies to overcome severe forms of PKU: The p.G46S as a model to identify small molecules modulators of protein aggregation and evaluation of an enzyme replacement approach using a nanoparticulate system. [Thesis]. Universidade de Lisboa; 2017. Available from: https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/34293

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

5. Sevsek, A. Guanidinium Iminosugars as Glycosidase Inhibitors.

Degree: 2017, University Utrecht

 Effective drug design to modulate biological processes requires knowledge of how substrates and ligands are recognized by their complementary enzymes and receptors. Glycoside trimming enzymes… (more)

Subjects/Keywords: pharmacological chaperones; inhibitors of beta-glucocerebrosidase; GBA; iminosugars

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APA (6th Edition):

Sevsek, A. (2017). Guanidinium Iminosugars as Glycosidase Inhibitors. (Doctoral Dissertation). University Utrecht. Retrieved from https://dspace.library.uu.nl/handle/1874/356097 ; URN:NBN:NL:UI:10-1874-356097 ; 1874/356097 ; urn:isbn:9789492679208 ; URN:NBN:NL:UI:10-1874-356097 ; https://dspace.library.uu.nl/handle/1874/356097

Chicago Manual of Style (16th Edition):

Sevsek, A. “Guanidinium Iminosugars as Glycosidase Inhibitors.” 2017. Doctoral Dissertation, University Utrecht. Accessed January 17, 2021. https://dspace.library.uu.nl/handle/1874/356097 ; URN:NBN:NL:UI:10-1874-356097 ; 1874/356097 ; urn:isbn:9789492679208 ; URN:NBN:NL:UI:10-1874-356097 ; https://dspace.library.uu.nl/handle/1874/356097.

MLA Handbook (7th Edition):

Sevsek, A. “Guanidinium Iminosugars as Glycosidase Inhibitors.” 2017. Web. 17 Jan 2021.

Vancouver:

Sevsek A. Guanidinium Iminosugars as Glycosidase Inhibitors. [Internet] [Doctoral dissertation]. University Utrecht; 2017. [cited 2021 Jan 17]. Available from: https://dspace.library.uu.nl/handle/1874/356097 ; URN:NBN:NL:UI:10-1874-356097 ; 1874/356097 ; urn:isbn:9789492679208 ; URN:NBN:NL:UI:10-1874-356097 ; https://dspace.library.uu.nl/handle/1874/356097.

Council of Science Editors:

Sevsek A. Guanidinium Iminosugars as Glycosidase Inhibitors. [Doctoral Dissertation]. University Utrecht; 2017. Available from: https://dspace.library.uu.nl/handle/1874/356097 ; URN:NBN:NL:UI:10-1874-356097 ; 1874/356097 ; urn:isbn:9789492679208 ; URN:NBN:NL:UI:10-1874-356097 ; https://dspace.library.uu.nl/handle/1874/356097

6. Decroocq, Camille. Conception et synthèse de nouvelles classes d'iminosucres d'intérêt thérapeutique : chimie click, multivalence et maladies génétiques rares : Design and synthesis of novel classes of iminosugars of therapeutic interest : click chemistry, multivalency and rare genetic diseases.

Degree: Docteur es, Chimie, 2012, Université de Strasbourg

Récemment, le concept de chaperon pharmacologique a émergé pour le traitement des maladies lysosomales. Comme inhibiteurs réversibles de glycosidases mutantes impliquées dans ces maladies, les… (more)

Subjects/Keywords: Iminosucres; Chaperons pharmacologiques; Inhibiteurs de glycosidases; Multivalence; Maladies lysosomales; Mucoviscidose; Cyclodextrines; Chimie click; Iminosugars; Pharmacological chaperones; Glycosidase inhibitors; Multivalency; Lysosomal diseases; Gauchers's disease; Cystic fibrosis; Click chemistry; 572.7

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APA (6th Edition):

Decroocq, C. (2012). Conception et synthèse de nouvelles classes d'iminosucres d'intérêt thérapeutique : chimie click, multivalence et maladies génétiques rares : Design and synthesis of novel classes of iminosugars of therapeutic interest : click chemistry, multivalency and rare genetic diseases. (Doctoral Dissertation). Université de Strasbourg. Retrieved from http://www.theses.fr/2012STRAF043

Chicago Manual of Style (16th Edition):

Decroocq, Camille. “Conception et synthèse de nouvelles classes d'iminosucres d'intérêt thérapeutique : chimie click, multivalence et maladies génétiques rares : Design and synthesis of novel classes of iminosugars of therapeutic interest : click chemistry, multivalency and rare genetic diseases.” 2012. Doctoral Dissertation, Université de Strasbourg. Accessed January 17, 2021. http://www.theses.fr/2012STRAF043.

MLA Handbook (7th Edition):

Decroocq, Camille. “Conception et synthèse de nouvelles classes d'iminosucres d'intérêt thérapeutique : chimie click, multivalence et maladies génétiques rares : Design and synthesis of novel classes of iminosugars of therapeutic interest : click chemistry, multivalency and rare genetic diseases.” 2012. Web. 17 Jan 2021.

Vancouver:

Decroocq C. Conception et synthèse de nouvelles classes d'iminosucres d'intérêt thérapeutique : chimie click, multivalence et maladies génétiques rares : Design and synthesis of novel classes of iminosugars of therapeutic interest : click chemistry, multivalency and rare genetic diseases. [Internet] [Doctoral dissertation]. Université de Strasbourg; 2012. [cited 2021 Jan 17]. Available from: http://www.theses.fr/2012STRAF043.

Council of Science Editors:

Decroocq C. Conception et synthèse de nouvelles classes d'iminosucres d'intérêt thérapeutique : chimie click, multivalence et maladies génétiques rares : Design and synthesis of novel classes of iminosugars of therapeutic interest : click chemistry, multivalency and rare genetic diseases. [Doctoral Dissertation]. Université de Strasbourg; 2012. Available from: http://www.theses.fr/2012STRAF043


Georgia Tech

7. Orwig, Susan D. Biophysical and structural characterization of proteins implicated in glaucoma and Gaucher disease.

Degree: PhD, Chemistry and Biochemistry, 2011, Georgia Tech

 The inherited form of primary open angle glaucoma, a disorder characterized by increased intraocular pressure and retina degeneration, is linked to mutations in the olfactomedin… (more)

Subjects/Keywords: Open-angle glaucoma; Pharmacological chaperones; High-throughput drug screen; Amyloid fibrils; Gaucher disease; Myocilin; Glaucoma; Eye Diseases; Eye Diseases Genetic aspects; Intraocular pressure; Body fluids Pressure; Eye

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APA (6th Edition):

Orwig, S. D. (2011). Biophysical and structural characterization of proteins implicated in glaucoma and Gaucher disease. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/45816

Chicago Manual of Style (16th Edition):

Orwig, Susan D. “Biophysical and structural characterization of proteins implicated in glaucoma and Gaucher disease.” 2011. Doctoral Dissertation, Georgia Tech. Accessed January 17, 2021. http://hdl.handle.net/1853/45816.

MLA Handbook (7th Edition):

Orwig, Susan D. “Biophysical and structural characterization of proteins implicated in glaucoma and Gaucher disease.” 2011. Web. 17 Jan 2021.

Vancouver:

Orwig SD. Biophysical and structural characterization of proteins implicated in glaucoma and Gaucher disease. [Internet] [Doctoral dissertation]. Georgia Tech; 2011. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/1853/45816.

Council of Science Editors:

Orwig SD. Biophysical and structural characterization of proteins implicated in glaucoma and Gaucher disease. [Doctoral Dissertation]. Georgia Tech; 2011. Available from: http://hdl.handle.net/1853/45816

8. Stauffert, Fabien. Conception et synthèse d’iminosucres di- à tétravalents comme sondes mécanistiques et agents thérapeutiques potentiels : Design and synthesis of di- or tetravalent iminosugars as mechanistic probes and potential therapeutic agents.

Degree: Docteur es, Chimie, 2015, Université de Strasbourg

Dans un contexte où les iminosucres multivalents représentent, en tant qu’inhibiteurs puissants de glycosidases, des structures privilégiées pour le développement de nouveaux agents thérapeutiques, nous… (more)

Subjects/Keywords: Iminosucres; Multivalence; Inhibiteurs de glycosidase; Mucoviscidose; Protéine CFTR; Correcteur; Maladie de Gaucher; Β-Glucocérébrosidase; Chaperons pharmacologiques; Chimie click; C-Glycoside; Iminosugars; Multivalency; Glycosidase inhibitors; Cystic fibrosis; CFTR corrector; Gaucher’s disease; Β-Glucocerebrosidase; Pharmacological chaperones; C-Glycoside; Click chemistry; 547.2

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APA (6th Edition):

Stauffert, F. (2015). Conception et synthèse d’iminosucres di- à tétravalents comme sondes mécanistiques et agents thérapeutiques potentiels : Design and synthesis of di- or tetravalent iminosugars as mechanistic probes and potential therapeutic agents. (Doctoral Dissertation). Université de Strasbourg. Retrieved from http://www.theses.fr/2015STRAF061

Chicago Manual of Style (16th Edition):

Stauffert, Fabien. “Conception et synthèse d’iminosucres di- à tétravalents comme sondes mécanistiques et agents thérapeutiques potentiels : Design and synthesis of di- or tetravalent iminosugars as mechanistic probes and potential therapeutic agents.” 2015. Doctoral Dissertation, Université de Strasbourg. Accessed January 17, 2021. http://www.theses.fr/2015STRAF061.

MLA Handbook (7th Edition):

Stauffert, Fabien. “Conception et synthèse d’iminosucres di- à tétravalents comme sondes mécanistiques et agents thérapeutiques potentiels : Design and synthesis of di- or tetravalent iminosugars as mechanistic probes and potential therapeutic agents.” 2015. Web. 17 Jan 2021.

Vancouver:

Stauffert F. Conception et synthèse d’iminosucres di- à tétravalents comme sondes mécanistiques et agents thérapeutiques potentiels : Design and synthesis of di- or tetravalent iminosugars as mechanistic probes and potential therapeutic agents. [Internet] [Doctoral dissertation]. Université de Strasbourg; 2015. [cited 2021 Jan 17]. Available from: http://www.theses.fr/2015STRAF061.

Council of Science Editors:

Stauffert F. Conception et synthèse d’iminosucres di- à tétravalents comme sondes mécanistiques et agents thérapeutiques potentiels : Design and synthesis of di- or tetravalent iminosugars as mechanistic probes and potential therapeutic agents. [Doctoral Dissertation]. Université de Strasbourg; 2015. Available from: http://www.theses.fr/2015STRAF061

9. Makley, Leah Nicole. Chemical Approaches for ‘Undruggable’ Targets: The Discovery of Ligands for Small Heat Shock Proteins.

Degree: PhD, Medicinal Chemistry, 2014, University of Michigan

 Small heat shock proteins (sHSPs) are molecular chaperones that protect against protein aggregation in response to stress. These chaperones have been linked to a number… (more)

Subjects/Keywords: Drug Discovery; Medicinal Chemistry; Undruggable Targets; Small Heat Shock Proteins; Pharmacological Chaperones; Protein Misfolding; Chemistry; Science

pharmacological#chaperones#to#recover#mutant## # # diseases# pathologies… …Pharmacological#chaperones#for#canonically#‘undruggable’#proteins# 3.4.#Differential#scanning… …fluorimetry#as#a#discovery#tool#for#pharmacological## # chaperones# # # # # # # # 3.5… …62# # # # # # 3. Pharmacological!rescue!of!an!aggregationOprone!small!heat!shock… …permeation#chromatography.# # 3.13.#Model#for#the#action#of#compound#29#as#a#pharmacological… 

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APA (6th Edition):

Makley, L. N. (2014). Chemical Approaches for ‘Undruggable’ Targets: The Discovery of Ligands for Small Heat Shock Proteins. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/109032

Chicago Manual of Style (16th Edition):

Makley, Leah Nicole. “Chemical Approaches for ‘Undruggable’ Targets: The Discovery of Ligands for Small Heat Shock Proteins.” 2014. Doctoral Dissertation, University of Michigan. Accessed January 17, 2021. http://hdl.handle.net/2027.42/109032.

MLA Handbook (7th Edition):

Makley, Leah Nicole. “Chemical Approaches for ‘Undruggable’ Targets: The Discovery of Ligands for Small Heat Shock Proteins.” 2014. Web. 17 Jan 2021.

Vancouver:

Makley LN. Chemical Approaches for ‘Undruggable’ Targets: The Discovery of Ligands for Small Heat Shock Proteins. [Internet] [Doctoral dissertation]. University of Michigan; 2014. [cited 2021 Jan 17]. Available from: http://hdl.handle.net/2027.42/109032.

Council of Science Editors:

Makley LN. Chemical Approaches for ‘Undruggable’ Targets: The Discovery of Ligands for Small Heat Shock Proteins. [Doctoral Dissertation]. University of Michigan; 2014. Available from: http://hdl.handle.net/2027.42/109032


University of Oulu

10. Hakalahti, A. (Anna). Human β1-adrenergic receptor:biosynthesis, processing and the carboxyl-terminal polymorphism.

Degree: 2011, University of Oulu

Abstract The β1-adrenergic receptor (β1AR) belongs to the large family of G protein-coupled receptors. It is activated by epinephrine and norepinephrine and thus has a… (more)

Subjects/Keywords: G-protein-coupled receptors; biosynthesis; down-regulation; glycosylation; left ventricular hypertrophy; limited proteolysis; metalloproteinases; myocardial infarction; pharmacological chaperones; single nucleotide polymorphism; up-regulation; β-adrenergic antagonist; β<; sub>; 1<; /sub>; -adrenergic receptor; G-proteiiniin kytketyt reseptorit; biosynteesi; farmakologiset kaperonit; glykosylaatio; metalloproteinaasit; rajoitettu proteolyysi; sydäninfarkti; vaimennussäätely; vasemman kammion hypertrofia; yksittäisen nukleotidin polymorfia; ylössäätely; β-adrenerginen antagonisti

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APA (6th Edition):

Hakalahti, A. (. (2011). Human β1-adrenergic receptor:biosynthesis, processing and the carboxyl-terminal polymorphism. (Doctoral Dissertation). University of Oulu. Retrieved from http://urn.fi/urn:isbn:9789514295263

Chicago Manual of Style (16th Edition):

Hakalahti, A (Anna). “Human β1-adrenergic receptor:biosynthesis, processing and the carboxyl-terminal polymorphism.” 2011. Doctoral Dissertation, University of Oulu. Accessed January 17, 2021. http://urn.fi/urn:isbn:9789514295263.

MLA Handbook (7th Edition):

Hakalahti, A (Anna). “Human β1-adrenergic receptor:biosynthesis, processing and the carboxyl-terminal polymorphism.” 2011. Web. 17 Jan 2021.

Vancouver:

Hakalahti A(. Human β1-adrenergic receptor:biosynthesis, processing and the carboxyl-terminal polymorphism. [Internet] [Doctoral dissertation]. University of Oulu; 2011. [cited 2021 Jan 17]. Available from: http://urn.fi/urn:isbn:9789514295263.

Council of Science Editors:

Hakalahti A(. Human β1-adrenergic receptor:biosynthesis, processing and the carboxyl-terminal polymorphism. [Doctoral Dissertation]. University of Oulu; 2011. Available from: http://urn.fi/urn:isbn:9789514295263

.