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You searched for subject:(PARP inhibitors). Showing records 1 – 13 of 13 total matches.

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Universitat Autònoma de Barcelona

1. Castroviejo Bermejo, Marta. RAD51 as functional biomarker to select tumors for PARP inhibitor treatment.

Degree: Departament de Bioquímica i Biologia Molecular, 2019, Universitat Autònoma de Barcelona

 Poly(ADP-ribose) polymerase (PARP) inhibitors (PARPi) are effective anticancer drugs in cancers with defective homologous recombination DNA repair (HRR), including cancers with mutations in BRCA1 and… (more)

Subjects/Keywords: RAD51; Inhibidors de PARP; Inhibidores de PARP; PARP inhibitors; Càncer de mama; Cáncer de mama; Breast cancer; Ciències Experimentals; 577

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Castroviejo Bermejo, M. (2019). RAD51 as functional biomarker to select tumors for PARP inhibitor treatment. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/667273

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Castroviejo Bermejo, Marta. “RAD51 as functional biomarker to select tumors for PARP inhibitor treatment.” 2019. Thesis, Universitat Autònoma de Barcelona. Accessed April 14, 2021. http://hdl.handle.net/10803/667273.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Castroviejo Bermejo, Marta. “RAD51 as functional biomarker to select tumors for PARP inhibitor treatment.” 2019. Web. 14 Apr 2021.

Vancouver:

Castroviejo Bermejo M. RAD51 as functional biomarker to select tumors for PARP inhibitor treatment. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2019. [cited 2021 Apr 14]. Available from: http://hdl.handle.net/10803/667273.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Castroviejo Bermejo M. RAD51 as functional biomarker to select tumors for PARP inhibitor treatment. [Thesis]. Universitat Autònoma de Barcelona; 2019. Available from: http://hdl.handle.net/10803/667273

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Boston University

2. O'Connor, Kevin William. Molecular determinants of sensitivity to poly(ADP-ribose) polymerase inhibitors in epithelial ovarian cancer.

Degree: MS, Medical Sciences, 2016, Boston University

 Less than half of patients with epithelial ovarian cancer (EOC) survive five years following diagnosis, underscoring the imperative need for improved treatment. Many patients, including… (more)

Subjects/Keywords: Oncology; PARP inhibitors; Homologous recombination; Ovarian cancer; Synthetic lethality

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APA (6th Edition):

O'Connor, K. W. (2016). Molecular determinants of sensitivity to poly(ADP-ribose) polymerase inhibitors in epithelial ovarian cancer. (Masters Thesis). Boston University. Retrieved from http://hdl.handle.net/2144/16827

Chicago Manual of Style (16th Edition):

O'Connor, Kevin William. “Molecular determinants of sensitivity to poly(ADP-ribose) polymerase inhibitors in epithelial ovarian cancer.” 2016. Masters Thesis, Boston University. Accessed April 14, 2021. http://hdl.handle.net/2144/16827.

MLA Handbook (7th Edition):

O'Connor, Kevin William. “Molecular determinants of sensitivity to poly(ADP-ribose) polymerase inhibitors in epithelial ovarian cancer.” 2016. Web. 14 Apr 2021.

Vancouver:

O'Connor KW. Molecular determinants of sensitivity to poly(ADP-ribose) polymerase inhibitors in epithelial ovarian cancer. [Internet] [Masters thesis]. Boston University; 2016. [cited 2021 Apr 14]. Available from: http://hdl.handle.net/2144/16827.

Council of Science Editors:

O'Connor KW. Molecular determinants of sensitivity to poly(ADP-ribose) polymerase inhibitors in epithelial ovarian cancer. [Masters Thesis]. Boston University; 2016. Available from: http://hdl.handle.net/2144/16827

3. Guillot, Clément. Potentiel des inhibiteurs de poly(ADP-ribose) polymérases seuls ou en combinaison avec la radiothérapie comme nouvelle option thérapeutique pour le carcinome hépatocellulaire : Potential of poly(ADP-ribose) polymerase inhibitors alone or in combination with radiation therapy as a new therapeutic option for hepatocellular carcinoma.

Degree: Docteur es, Cancérologie, 2013, Université Claude Bernard – Lyon I

Le carcinome hépatocellulaire est l'un des cancers les plus fréquents et des plus sévères à travers le monde. Le diagnostic est souvent tardif et les… (more)

Subjects/Keywords: Carcinome hépatocellulaire; Poly(ADP-ribose) polymérases; Inhibiteurs de PARP; Radiothérapie; Hepatocellular carcinoma; Poly(ADP-ribose) polymerases; PARP inhibitors; Radiation therapy; 616.994

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APA (6th Edition):

Guillot, C. (2013). Potentiel des inhibiteurs de poly(ADP-ribose) polymérases seuls ou en combinaison avec la radiothérapie comme nouvelle option thérapeutique pour le carcinome hépatocellulaire : Potential of poly(ADP-ribose) polymerase inhibitors alone or in combination with radiation therapy as a new therapeutic option for hepatocellular carcinoma. (Doctoral Dissertation). Université Claude Bernard – Lyon I. Retrieved from http://www.theses.fr/2013LYO10281

Chicago Manual of Style (16th Edition):

Guillot, Clément. “Potentiel des inhibiteurs de poly(ADP-ribose) polymérases seuls ou en combinaison avec la radiothérapie comme nouvelle option thérapeutique pour le carcinome hépatocellulaire : Potential of poly(ADP-ribose) polymerase inhibitors alone or in combination with radiation therapy as a new therapeutic option for hepatocellular carcinoma.” 2013. Doctoral Dissertation, Université Claude Bernard – Lyon I. Accessed April 14, 2021. http://www.theses.fr/2013LYO10281.

MLA Handbook (7th Edition):

Guillot, Clément. “Potentiel des inhibiteurs de poly(ADP-ribose) polymérases seuls ou en combinaison avec la radiothérapie comme nouvelle option thérapeutique pour le carcinome hépatocellulaire : Potential of poly(ADP-ribose) polymerase inhibitors alone or in combination with radiation therapy as a new therapeutic option for hepatocellular carcinoma.” 2013. Web. 14 Apr 2021.

Vancouver:

Guillot C. Potentiel des inhibiteurs de poly(ADP-ribose) polymérases seuls ou en combinaison avec la radiothérapie comme nouvelle option thérapeutique pour le carcinome hépatocellulaire : Potential of poly(ADP-ribose) polymerase inhibitors alone or in combination with radiation therapy as a new therapeutic option for hepatocellular carcinoma. [Internet] [Doctoral dissertation]. Université Claude Bernard – Lyon I; 2013. [cited 2021 Apr 14]. Available from: http://www.theses.fr/2013LYO10281.

Council of Science Editors:

Guillot C. Potentiel des inhibiteurs de poly(ADP-ribose) polymérases seuls ou en combinaison avec la radiothérapie comme nouvelle option thérapeutique pour le carcinome hépatocellulaire : Potential of poly(ADP-ribose) polymerase inhibitors alone or in combination with radiation therapy as a new therapeutic option for hepatocellular carcinoma. [Doctoral Dissertation]. Université Claude Bernard – Lyon I; 2013. Available from: http://www.theses.fr/2013LYO10281

4. Morel, Daphné. Identifying Synthetic Lethal and Selective Approaches to Target PBRM1-Deficiency in Clear Cell Renal Cell Carcinoma : Exploration de stratégies thérapeutiques ciblant la déficience en PBRM1 dans les carcinomes rénaux à cellules claires.

Degree: Docteur es, Aspects moléculaires et cellulaires de la biologie, 2020, université Paris-Saclay

L’inactivation de polybromo-1 (PBRM1) est un évènement fréquent dans de nombreux cancers. En particulier, les carcinomes rénaux à cellules claires présentent une déficience en PBRM1… (more)

Subjects/Keywords: Pbrm1; Létalité synthétique; Inhibiteurs de PARP; Cancer du rein; Kidney cancer; Synthetic lethality; PARP inhibitors; Pbrm1

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APA (6th Edition):

Morel, D. (2020). Identifying Synthetic Lethal and Selective Approaches to Target PBRM1-Deficiency in Clear Cell Renal Cell Carcinoma : Exploration de stratégies thérapeutiques ciblant la déficience en PBRM1 dans les carcinomes rénaux à cellules claires. (Doctoral Dissertation). université Paris-Saclay. Retrieved from http://www.theses.fr/2020UPASL017

Chicago Manual of Style (16th Edition):

Morel, Daphné. “Identifying Synthetic Lethal and Selective Approaches to Target PBRM1-Deficiency in Clear Cell Renal Cell Carcinoma : Exploration de stratégies thérapeutiques ciblant la déficience en PBRM1 dans les carcinomes rénaux à cellules claires.” 2020. Doctoral Dissertation, université Paris-Saclay. Accessed April 14, 2021. http://www.theses.fr/2020UPASL017.

MLA Handbook (7th Edition):

Morel, Daphné. “Identifying Synthetic Lethal and Selective Approaches to Target PBRM1-Deficiency in Clear Cell Renal Cell Carcinoma : Exploration de stratégies thérapeutiques ciblant la déficience en PBRM1 dans les carcinomes rénaux à cellules claires.” 2020. Web. 14 Apr 2021.

Vancouver:

Morel D. Identifying Synthetic Lethal and Selective Approaches to Target PBRM1-Deficiency in Clear Cell Renal Cell Carcinoma : Exploration de stratégies thérapeutiques ciblant la déficience en PBRM1 dans les carcinomes rénaux à cellules claires. [Internet] [Doctoral dissertation]. université Paris-Saclay; 2020. [cited 2021 Apr 14]. Available from: http://www.theses.fr/2020UPASL017.

Council of Science Editors:

Morel D. Identifying Synthetic Lethal and Selective Approaches to Target PBRM1-Deficiency in Clear Cell Renal Cell Carcinoma : Exploration de stratégies thérapeutiques ciblant la déficience en PBRM1 dans les carcinomes rénaux à cellules claires. [Doctoral Dissertation]. université Paris-Saclay; 2020. Available from: http://www.theses.fr/2020UPASL017


Texas Medical Center

5. Yam, Clinton. ROLE OF c-MET and EGFR IN ACQUIRED RESISTANCE TO PARP INHIBITORS IN TRIPLE-NEGATIVE BREAST CANCER.

Degree: MS, 2019, Texas Medical Center

  Triple-negative breast cancer is associated with a poor prognosis and treatment options are limited. The Poly (ADP-ribose) polymerase (PARP) inhibitors, olaparib and talazoparib, were… (more)

Subjects/Keywords: Triple-negative breast cancer; PARP inhibitors; resistance; c-MET; EGFR; Biology; Medicine and Health Sciences

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APA (6th Edition):

Yam, C. (2019). ROLE OF c-MET and EGFR IN ACQUIRED RESISTANCE TO PARP INHIBITORS IN TRIPLE-NEGATIVE BREAST CANCER. (Thesis). Texas Medical Center. Retrieved from https://digitalcommons.library.tmc.edu/utgsbs_dissertations/952

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Yam, Clinton. “ROLE OF c-MET and EGFR IN ACQUIRED RESISTANCE TO PARP INHIBITORS IN TRIPLE-NEGATIVE BREAST CANCER.” 2019. Thesis, Texas Medical Center. Accessed April 14, 2021. https://digitalcommons.library.tmc.edu/utgsbs_dissertations/952.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Yam, Clinton. “ROLE OF c-MET and EGFR IN ACQUIRED RESISTANCE TO PARP INHIBITORS IN TRIPLE-NEGATIVE BREAST CANCER.” 2019. Web. 14 Apr 2021.

Vancouver:

Yam C. ROLE OF c-MET and EGFR IN ACQUIRED RESISTANCE TO PARP INHIBITORS IN TRIPLE-NEGATIVE BREAST CANCER. [Internet] [Thesis]. Texas Medical Center; 2019. [cited 2021 Apr 14]. Available from: https://digitalcommons.library.tmc.edu/utgsbs_dissertations/952.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Yam C. ROLE OF c-MET and EGFR IN ACQUIRED RESISTANCE TO PARP INHIBITORS IN TRIPLE-NEGATIVE BREAST CANCER. [Thesis]. Texas Medical Center; 2019. Available from: https://digitalcommons.library.tmc.edu/utgsbs_dissertations/952

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Cambridge

6. Ogden, Tom. Studies of PARP-1 activation and inhibition using NMR spectroscopy.

Degree: PhD, University of Cambridge

 Poly(ADP-ribose)polymerase 1 (PARP-1) is a highly abundant multi-domain chromatin-associated enzyme found in all higher eukaryotic cell nuclei. It is the founding member of the PARP(more)

Subjects/Keywords: PARP-1; PARP inhibitors; PARP inhibition; DNA damage response; ADP-ribose; ADP-ribosylation; NMR spectroscopy; Biomolecular NMR

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APA (6th Edition):

Ogden, T. (n.d.). Studies of PARP-1 activation and inhibition using NMR spectroscopy. (Doctoral Dissertation). University of Cambridge. Retrieved from https://www.repository.cam.ac.uk/handle/1810/300822

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Chicago Manual of Style (16th Edition):

Ogden, Tom. “Studies of PARP-1 activation and inhibition using NMR spectroscopy.” Doctoral Dissertation, University of Cambridge. Accessed April 14, 2021. https://www.repository.cam.ac.uk/handle/1810/300822.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

MLA Handbook (7th Edition):

Ogden, Tom. “Studies of PARP-1 activation and inhibition using NMR spectroscopy.” Web. 14 Apr 2021.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Vancouver:

Ogden T. Studies of PARP-1 activation and inhibition using NMR spectroscopy. [Internet] [Doctoral dissertation]. University of Cambridge; [cited 2021 Apr 14]. Available from: https://www.repository.cam.ac.uk/handle/1810/300822.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Council of Science Editors:

Ogden T. Studies of PARP-1 activation and inhibition using NMR spectroscopy. [Doctoral Dissertation]. University of Cambridge; Available from: https://www.repository.cam.ac.uk/handle/1810/300822

Note: this citation may be lacking information needed for this citation format:
No year of publication.

7. Jdey, Wael. Mécanismes de sensibilité/résistance des cellules tumorales aux inhibiteurs de réparation de l'ADN Dbait. : Mechanisms of tumor cells' sensitivity/resistance to the DNA repair inhibitors Dbait.

Degree: Docteur es, Aspects moléculaires et cellulaires de la biologie, 2016, Université Paris-Saclay (ComUE)

 Les défauts dans les voies de réparation de l’ADN sont aujourd’hui largement exploités pour le traitement du cancer. En effet, la capacité des tumeurs à… (more)

Subjects/Keywords: Dbait; Biomarqueurs prédictifs; Mécanismes de résistance; Cancer du sein triple négatif; Inhibiteurs de PARP; Réparation de l'ADN; Dbait; Predictive biomarkers; Mechanisms of resistance; Triple negative Breast cancer; PARP inhibitors; DNA repair

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APA (6th Edition):

Jdey, W. (2016). Mécanismes de sensibilité/résistance des cellules tumorales aux inhibiteurs de réparation de l'ADN Dbait. : Mechanisms of tumor cells' sensitivity/resistance to the DNA repair inhibitors Dbait. (Doctoral Dissertation). Université Paris-Saclay (ComUE). Retrieved from http://www.theses.fr/2016SACLS463

Chicago Manual of Style (16th Edition):

Jdey, Wael. “Mécanismes de sensibilité/résistance des cellules tumorales aux inhibiteurs de réparation de l'ADN Dbait. : Mechanisms of tumor cells' sensitivity/resistance to the DNA repair inhibitors Dbait.” 2016. Doctoral Dissertation, Université Paris-Saclay (ComUE). Accessed April 14, 2021. http://www.theses.fr/2016SACLS463.

MLA Handbook (7th Edition):

Jdey, Wael. “Mécanismes de sensibilité/résistance des cellules tumorales aux inhibiteurs de réparation de l'ADN Dbait. : Mechanisms of tumor cells' sensitivity/resistance to the DNA repair inhibitors Dbait.” 2016. Web. 14 Apr 2021.

Vancouver:

Jdey W. Mécanismes de sensibilité/résistance des cellules tumorales aux inhibiteurs de réparation de l'ADN Dbait. : Mechanisms of tumor cells' sensitivity/resistance to the DNA repair inhibitors Dbait. [Internet] [Doctoral dissertation]. Université Paris-Saclay (ComUE); 2016. [cited 2021 Apr 14]. Available from: http://www.theses.fr/2016SACLS463.

Council of Science Editors:

Jdey W. Mécanismes de sensibilité/résistance des cellules tumorales aux inhibiteurs de réparation de l'ADN Dbait. : Mechanisms of tumor cells' sensitivity/resistance to the DNA repair inhibitors Dbait. [Doctoral Dissertation]. Université Paris-Saclay (ComUE); 2016. Available from: http://www.theses.fr/2016SACLS463

8. Brandsma, Inger. Balancing Pathways in DNA Double Strand Break Repair.

Degree: 2016, Erasmus University Medical Center

 All information a cell needs to live and survive is stored in the genomic DNA. Maintenance of an intact and uncompromised genome is of vital… (more)

Subjects/Keywords: Breast Cancer; DNA repair; DNA damage Response; BRCA1; BRCA2; PARP inhibitors

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APA (6th Edition):

Brandsma, I. (2016). Balancing Pathways in DNA Double Strand Break Repair. (Doctoral Dissertation). Erasmus University Medical Center. Retrieved from http://hdl.handle.net/1765/80038

Chicago Manual of Style (16th Edition):

Brandsma, Inger. “Balancing Pathways in DNA Double Strand Break Repair.” 2016. Doctoral Dissertation, Erasmus University Medical Center. Accessed April 14, 2021. http://hdl.handle.net/1765/80038.

MLA Handbook (7th Edition):

Brandsma, Inger. “Balancing Pathways in DNA Double Strand Break Repair.” 2016. Web. 14 Apr 2021.

Vancouver:

Brandsma I. Balancing Pathways in DNA Double Strand Break Repair. [Internet] [Doctoral dissertation]. Erasmus University Medical Center; 2016. [cited 2021 Apr 14]. Available from: http://hdl.handle.net/1765/80038.

Council of Science Editors:

Brandsma I. Balancing Pathways in DNA Double Strand Break Repair. [Doctoral Dissertation]. Erasmus University Medical Center; 2016. Available from: http://hdl.handle.net/1765/80038


Université Paris-Sud – Paris XI

9. Croset, Amélie. Identification et caractérisation des mécanismes d'action des molécules appats, les SiDNA, dans l'inhibition des voies de réparation des cassures simple-brin : Identification and characterization of bait molecules mechanisms of action, the SIDNA, in the inhibition of single strand break repair pathway.

Degree: Docteur es, Cancérologie, radiobiologie, 2013, Université Paris-Sud – Paris XI

La plupart des traitements anticancéreux, comme la chimiothérapie ou la radiothérapie, sont cytotoxiques et causent des dommages à l'ADN dans le but d’induire la mort… (more)

Subjects/Keywords: SiDNA; Inhibiteurs des voies de réparation de l’ADN; Poly Adenosine Diphosphate Ribose Polymerase (PARP); Protéine Kinase ADN Dépendant (DNA-PK); Signalisation des dommages à l'ADN; Protéines BRCA; Instabilité génétique; Traitement des Cancers; SiDNA; DNA Repair Inhibitors; Poly Adenosine Diphosphate Ribose Polymerase (PARP); DNA-Activated Protein Kinase (DNA-PK); DNA Damage Signaling; BReast CAncer; Genetic Instability; Cancer Treatement

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APA (6th Edition):

Croset, A. (2013). Identification et caractérisation des mécanismes d'action des molécules appats, les SiDNA, dans l'inhibition des voies de réparation des cassures simple-brin : Identification and characterization of bait molecules mechanisms of action, the SIDNA, in the inhibition of single strand break repair pathway. (Doctoral Dissertation). Université Paris-Sud – Paris XI. Retrieved from http://www.theses.fr/2013PA11T018

Chicago Manual of Style (16th Edition):

Croset, Amélie. “Identification et caractérisation des mécanismes d'action des molécules appats, les SiDNA, dans l'inhibition des voies de réparation des cassures simple-brin : Identification and characterization of bait molecules mechanisms of action, the SIDNA, in the inhibition of single strand break repair pathway.” 2013. Doctoral Dissertation, Université Paris-Sud – Paris XI. Accessed April 14, 2021. http://www.theses.fr/2013PA11T018.

MLA Handbook (7th Edition):

Croset, Amélie. “Identification et caractérisation des mécanismes d'action des molécules appats, les SiDNA, dans l'inhibition des voies de réparation des cassures simple-brin : Identification and characterization of bait molecules mechanisms of action, the SIDNA, in the inhibition of single strand break repair pathway.” 2013. Web. 14 Apr 2021.

Vancouver:

Croset A. Identification et caractérisation des mécanismes d'action des molécules appats, les SiDNA, dans l'inhibition des voies de réparation des cassures simple-brin : Identification and characterization of bait molecules mechanisms of action, the SIDNA, in the inhibition of single strand break repair pathway. [Internet] [Doctoral dissertation]. Université Paris-Sud – Paris XI; 2013. [cited 2021 Apr 14]. Available from: http://www.theses.fr/2013PA11T018.

Council of Science Editors:

Croset A. Identification et caractérisation des mécanismes d'action des molécules appats, les SiDNA, dans l'inhibition des voies de réparation des cassures simple-brin : Identification and characterization of bait molecules mechanisms of action, the SIDNA, in the inhibition of single strand break repair pathway. [Doctoral Dissertation]. Université Paris-Sud – Paris XI; 2013. Available from: http://www.theses.fr/2013PA11T018


Leiden University

10. Annunziato, S. Precision modeling of breast cancer in the CRISPR era.

Degree: 2020, Leiden University

  The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes. While the Holy Grail… (more)

Subjects/Keywords: breast cancer; mouse models; CRISPR-Cas9; gene editing; somatic models; intraductal injection; oncogenomics; genetic screens; drug resistance; PARP inhibitors

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APA (6th Edition):

Annunziato, S. (2020). Precision modeling of breast cancer in the CRISPR era. (Doctoral Dissertation). Leiden University. Retrieved from http://hdl.handle.net/1887/82703

Chicago Manual of Style (16th Edition):

Annunziato, S. “Precision modeling of breast cancer in the CRISPR era.” 2020. Doctoral Dissertation, Leiden University. Accessed April 14, 2021. http://hdl.handle.net/1887/82703.

MLA Handbook (7th Edition):

Annunziato, S. “Precision modeling of breast cancer in the CRISPR era.” 2020. Web. 14 Apr 2021.

Vancouver:

Annunziato S. Precision modeling of breast cancer in the CRISPR era. [Internet] [Doctoral dissertation]. Leiden University; 2020. [cited 2021 Apr 14]. Available from: http://hdl.handle.net/1887/82703.

Council of Science Editors:

Annunziato S. Precision modeling of breast cancer in the CRISPR era. [Doctoral Dissertation]. Leiden University; 2020. Available from: http://hdl.handle.net/1887/82703

11. Finch, Kristin E. The discovery of small molecule inhibitors of poly(ADP-ribose) mediated cell death.

Degree: PhD, 0335, 2011, University of Illinois – Urbana-Champaign

 The emergence of resistance to cancer treatments through methods that generate cell death by inducing DNA damage, such as chemotherapeutics and radiation therapy, is a… (more)

Subjects/Keywords: poly(ADP-ribose) glycohydrolase (PARG); Poly(ADP-ribose) polymerase (PARP); poly(ADP-ribose) (PAR); Rhodanines; small molecule inhibitors

…of PARP-2 specific inhibitors.40 Tankyrase-1 and -2 have very intriguing functions outside… …section 1.3.1), a synergistic effect of PARP inhibitors and DNA alkylating agents has been… …noted. Today’s success with PARP inhibitors was foreshadowed when Durkacz et al. observed… …increased cytotoxicity when PARP inhibitors were co-treated with dimethyl sulphate, a DNA… …confirmed by the use of small molecule inhibitors of PARP as described in much of the early… 

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APA (6th Edition):

Finch, K. E. (2011). The discovery of small molecule inhibitors of poly(ADP-ribose) mediated cell death. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/24355

Chicago Manual of Style (16th Edition):

Finch, Kristin E. “The discovery of small molecule inhibitors of poly(ADP-ribose) mediated cell death.” 2011. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed April 14, 2021. http://hdl.handle.net/2142/24355.

MLA Handbook (7th Edition):

Finch, Kristin E. “The discovery of small molecule inhibitors of poly(ADP-ribose) mediated cell death.” 2011. Web. 14 Apr 2021.

Vancouver:

Finch KE. The discovery of small molecule inhibitors of poly(ADP-ribose) mediated cell death. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2011. [cited 2021 Apr 14]. Available from: http://hdl.handle.net/2142/24355.

Council of Science Editors:

Finch KE. The discovery of small molecule inhibitors of poly(ADP-ribose) mediated cell death. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2011. Available from: http://hdl.handle.net/2142/24355

12. Sulier, Kiaya Minh-Li. Developing 1,2,3,4-tetrahydro-5H-aryl[1,4]diazepin-5-ones and Related Scaffolds as Poly-(ADP-ribosyl) Polymerase (PARP) Inhibitors and Exploring Their Targeted Polypharmacology with Kinases.

Degree: MS, Chemistry, 2017, Virginia Tech

 Poly-(ADP-ribsoyl) Polymerases (PARPs) are a superfamily of enzymes comprised of 17 known isoforms. PARP inhibitors (PARPi) have shown success in clinical trials for the treatment… (more)

Subjects/Keywords: Poly-(ADP-Ribosyl) Polymerase (PARP); cyclin-dependent kinase 1 (CDK1); triple negative breast cancer (TNBC); benzodiazepines; isoform specific inhibitors

…the first basic scaffold for PARP inhibitors, which led to the first class of benzamide… …analog inhibitors. Despite the initial success, these compounds only inhibited PARP in… …reported PARP inhibitors, including the PARP inhibitors in clinical trials, show little to no… …PARP isoform selectivity. PARP inhibitors classified as “PARP”, “PARP1”, “PARP2”, or “PARP1/2… …of PARP inhibitors, the need for isoform selective PARP inhibitors is increasing. Isoform… 

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APA (6th Edition):

Sulier, K. M. (2017). Developing 1,2,3,4-tetrahydro-5H-aryl[1,4]diazepin-5-ones and Related Scaffolds as Poly-(ADP-ribosyl) Polymerase (PARP) Inhibitors and Exploring Their Targeted Polypharmacology with Kinases. (Masters Thesis). Virginia Tech. Retrieved from http://hdl.handle.net/10919/86200

Chicago Manual of Style (16th Edition):

Sulier, Kiaya Minh-Li. “Developing 1,2,3,4-tetrahydro-5H-aryl[1,4]diazepin-5-ones and Related Scaffolds as Poly-(ADP-ribosyl) Polymerase (PARP) Inhibitors and Exploring Their Targeted Polypharmacology with Kinases.” 2017. Masters Thesis, Virginia Tech. Accessed April 14, 2021. http://hdl.handle.net/10919/86200.

MLA Handbook (7th Edition):

Sulier, Kiaya Minh-Li. “Developing 1,2,3,4-tetrahydro-5H-aryl[1,4]diazepin-5-ones and Related Scaffolds as Poly-(ADP-ribosyl) Polymerase (PARP) Inhibitors and Exploring Their Targeted Polypharmacology with Kinases.” 2017. Web. 14 Apr 2021.

Vancouver:

Sulier KM. Developing 1,2,3,4-tetrahydro-5H-aryl[1,4]diazepin-5-ones and Related Scaffolds as Poly-(ADP-ribosyl) Polymerase (PARP) Inhibitors and Exploring Their Targeted Polypharmacology with Kinases. [Internet] [Masters thesis]. Virginia Tech; 2017. [cited 2021 Apr 14]. Available from: http://hdl.handle.net/10919/86200.

Council of Science Editors:

Sulier KM. Developing 1,2,3,4-tetrahydro-5H-aryl[1,4]diazepin-5-ones and Related Scaffolds as Poly-(ADP-ribosyl) Polymerase (PARP) Inhibitors and Exploring Their Targeted Polypharmacology with Kinases. [Masters Thesis]. Virginia Tech; 2017. Available from: http://hdl.handle.net/10919/86200


Université de Montréal

13. Fleury, Hubert. Implication des inhibiteurs de PARP dans le cancer de l’ovaire.

Degree: 2018, Université de Montréal

Subjects/Keywords: Séreux de haut grade; Cancer épithélial de l'ovaire; lignée cellulaire; mutation BRCA; inhibiteurs de PARP; Olaparib; réparation de l'ADN; NER; MMR; sénescence; arrêt du cycle cellulaire; combinaison thérapeutique; high-grade serous; ovarian epithelial; cell line; BRCA mutation; PARP inhibitors; Olaparib; DNA repair; NER; MMR; senescence; cell cycle arrest; therapeutic combination; Biology - Molecular / Biologie - Biologie moléculaire (UMI : 0307)

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Fleury, H. (2018). Implication des inhibiteurs de PARP dans le cancer de l’ovaire. (Thesis). Université de Montréal. Retrieved from http://hdl.handle.net/1866/20221

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Fleury, Hubert. “Implication des inhibiteurs de PARP dans le cancer de l’ovaire.” 2018. Thesis, Université de Montréal. Accessed April 14, 2021. http://hdl.handle.net/1866/20221.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Fleury, Hubert. “Implication des inhibiteurs de PARP dans le cancer de l’ovaire.” 2018. Web. 14 Apr 2021.

Vancouver:

Fleury H. Implication des inhibiteurs de PARP dans le cancer de l’ovaire. [Internet] [Thesis]. Université de Montréal; 2018. [cited 2021 Apr 14]. Available from: http://hdl.handle.net/1866/20221.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Fleury H. Implication des inhibiteurs de PARP dans le cancer de l’ovaire. [Thesis]. Université de Montréal; 2018. Available from: http://hdl.handle.net/1866/20221

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

.