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Mississippi State University
1.
Gong, Zhiyong.
Single particle studies using optical trapping and manipulation.
Degree: PhD, Applied Physics, 2019, Mississippi State University
URL: http://sun.library.msstate.edu/ETD-db/theses/available/etd-03152019-131708/
;
► Particles of nanometer- and micrometer-size, including diverse types of aerosol, dusts, and material powders, pose significant influence on environment, climate, human health, and material…
(more)
▼ Particles of nanometer- and micrometer-size, including diverse types of aerosol, dusts, and material powders, pose significant influence on environment, climate, human health, and material properties. Our understanding towards these particles and materials is mainly established from bulk samples and from particles deposited on substrates or dispersed in liquid solutions. However, fundamental properties and interactions of single particles cannot be fully resolved by characterizing bulk materials or deposited particles. Pristine physicochemical properties and rudimentary gas-particle interactions can only be investigated from single particles in their native states.
The goal of this dissertation is to study single particles in gaseous environment with minimum external interferences. Diverse
optical trapping (OT) methods for
trapping and manipulating single airborne particles were explored and summarized. These configurations are categorized into radiation-pressure traps, photophoretic traps, and universal
optical traps (UOT), according to particles absorbance. The UOT configurations are able to trap and manipulate a wide variety of single particles, including transparent and absorbing, spherical and irregular, inorganic and biological particles. Four key aspects of these OTs, simplicity, robustness, flexibility, and efficiency, are brought up to evaluate OT capabilities, providing a guidance to select the optimal
optical configuration for specific applications.
With single particles stably trapped,
optical manipulations and characterizations can therefore be interrogated. Single-particle manipulations in air from one-dimension to three-dimension are reviewed; pulling and pushing single optically trapped particles along a Gaussian laser beam were explored and explained. Cavity ringdown spectroscopy is integrated with OTs to measure the light extinctions of trapped particles. Microscopic imaging and Raman systems are combined with the OT to examine the trapped particles. A few application examples of this
optical trapping-Raman spectroscopy system are demonstrated, including online characterizing carbon particles, effectively bleaching fluorescence in dye-doped polymer microspheres, acquiring clean Raman spectra of single biological particles, and monitoring chemical reactions in single biological particles.
Optical trapping, associated with advanced laser spectroscopic techniques, offer a great flexibility for
trapping, manipulating, characterizing, and monitoring single particles in air.
Advisors/Committee Members: Chuji Wang (chair), Hendrik F. Arnoldus (committee member), Gombojav Ariunbold (committee member), Lei Chen (committee member), Yong-Le Pan (committee member).
Subjects/Keywords: Raman spectroscopy; cavity ringdown spectroscopy; optical manipulation; optical trapping; single particles
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APA (6th Edition):
Gong, Z. (2019). Single particle studies using optical trapping and manipulation. (Doctoral Dissertation). Mississippi State University. Retrieved from http://sun.library.msstate.edu/ETD-db/theses/available/etd-03152019-131708/ ;
Chicago Manual of Style (16th Edition):
Gong, Zhiyong. “Single particle studies using optical trapping and manipulation.” 2019. Doctoral Dissertation, Mississippi State University. Accessed March 04, 2021.
http://sun.library.msstate.edu/ETD-db/theses/available/etd-03152019-131708/ ;.
MLA Handbook (7th Edition):
Gong, Zhiyong. “Single particle studies using optical trapping and manipulation.” 2019. Web. 04 Mar 2021.
Vancouver:
Gong Z. Single particle studies using optical trapping and manipulation. [Internet] [Doctoral dissertation]. Mississippi State University; 2019. [cited 2021 Mar 04].
Available from: http://sun.library.msstate.edu/ETD-db/theses/available/etd-03152019-131708/ ;.
Council of Science Editors:
Gong Z. Single particle studies using optical trapping and manipulation. [Doctoral Dissertation]. Mississippi State University; 2019. Available from: http://sun.library.msstate.edu/ETD-db/theses/available/etd-03152019-131708/ ;

University of Maryland
2.
Liu, Yuxiang.
Fiber Optical Tweezers for Microscale and Nanoscale Particle Manipulation and Force Sensing.
Degree: Mechanical Engineering, 2011, University of Maryland
URL: http://hdl.handle.net/1903/11466
► Optical tweezers have been an important tool in biology and physics for studying single molecules and colloidal systems. Most of current optical tweezers are built…
(more)
▼ Optical tweezers have been an important tool in biology and physics for studying single molecules and colloidal systems. Most of current
optical tweezers are built with microscope objectives, which are: i) expensive, ii) bulky and hard to integrate, iii) sensitive to environmental fluctuations, iv) limited in terms of working distances from the substrate, and v) rigid with the requirements on the substrate (transparent substrate made with glass and with a fixed thickness). These limitations of objective-based
optical tweezers prevent them from being miniaturized. Fiber
optical tweezers can provide a solution for cost reduction and miniaturization, and these
optical tweezers can be potentially used in microfluidic systems. However, the existing fiber
optical tweezers have the following limitations: i) low
trapping efficiency due to weakly focused beams, ii) lack of the ability to control the positions of multiple particles simultaneously, and iii) limited functionalities.
The overall objective of this dissertation work is to further the fundamental understanding of fiber
optical tweezers through experimental study and modeling, and to develop novel fiber
optical tweezers systems to enhance the capability and functionalities of fiber
optical tweezers as microscale and nanoscale manipulators/sensors. The contributions of this dissertation work are summarized as follows: i) An enhanced understanding of the inclined dual-fiber
optical tweezers (DFOTs) system has been achieved. Stable three dimensional (3D)
optical trapping of a single micron-sized particle has been experimentally demonstrated. This is the first time that the
trapping efficiency has been calibrated and the stiffness of the trap has been obtained in the experiments, which has been carried out by using two methods: the drag force method and power spectrum analysis. Such calibration enables the system to be used as a picoNewton-level force sensor in addition to a particle manipulator. The influence of system parameters on the
trapping performance has been carefully investigated through both experimental and numerical studies. ii) Multiple traps have been created and carefully studied with the inclined DFOTs for the first time. Three traps, one 3D trap and two 2D traps, have been experimentally created at different vertical levels with adjustable separations and positions. iii) Multiple functionalities have been achieved and studied for the first time with the inclined DFOTs. Particle separation, grouping, stacking, rod alignment, rod rotation, and
optical binding have been experimentally demonstrated. The multiple functionalities allow the inclined DFOTs to find applications in the study of interaction forces in colloidal systems as well as parallel particle
manipulation in drug delivery systems. iv) Far-field superfocusing effect has been investigated and successfully demonstrated with a fiber-based surface plasmonic (SP) lens for the first time. A planar SP lens with a set of concentric nanoscale rings on a fiber endface has been developed. For the first…
Advisors/Committee Members: Yu, Miao (advisor).
Subjects/Keywords: Mechanical Engineering; Optics; Nanotechnology; fiber-based superfocusing; fiber optical tweezers; multiple optical traps; three-dimensional nanoparticle manipulation; three-dimensional optical trapping
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
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APA (6th Edition):
Liu, Y. (2011). Fiber Optical Tweezers for Microscale and Nanoscale Particle Manipulation and Force Sensing. (Thesis). University of Maryland. Retrieved from http://hdl.handle.net/1903/11466
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Liu, Yuxiang. “Fiber Optical Tweezers for Microscale and Nanoscale Particle Manipulation and Force Sensing.” 2011. Thesis, University of Maryland. Accessed March 04, 2021.
http://hdl.handle.net/1903/11466.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Liu, Yuxiang. “Fiber Optical Tweezers for Microscale and Nanoscale Particle Manipulation and Force Sensing.” 2011. Web. 04 Mar 2021.
Vancouver:
Liu Y. Fiber Optical Tweezers for Microscale and Nanoscale Particle Manipulation and Force Sensing. [Internet] [Thesis]. University of Maryland; 2011. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/1903/11466.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Liu Y. Fiber Optical Tweezers for Microscale and Nanoscale Particle Manipulation and Force Sensing. [Thesis]. University of Maryland; 2011. Available from: http://hdl.handle.net/1903/11466
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
3.
Tkachenko, Georgiy.
Optical trapping and manipulation of chiral microspheres controlled by the photon helicity : Le piégeage et la manipulation optique de microsphères chiraux contrôlées par l'hélicité du photon.
Degree: Docteur es, Laser, matière et nanosciences, 2014, Bordeaux
URL: http://www.theses.fr/2014BORD0102
► Exploiter le degré de liberté angulaire de la lumière pour contrôler les forces optiques ouvre une nouvelle voie pour la manipulation optique de systèmes matériels.…
(more)
▼ Exploiter le degré de liberté angulaire de la lumière pour contrôler les forces optiques ouvre une nouvelle voie pour la manipulation optique de systèmes matériels. Dans ce contexte, notre travail porte sur l’interaction lumière-matière en présence de chiralité, qu’elle soit matérielle ou ondulatoire. Expérimentalement, nous avons utilisé des gouttes de cristaux liquides cholestériques interagissant avec un ou plusieurs champs lumineux polarisés circulairement et nous avons apporté une description quantitative de nos observations. Notre principal résultat correspond à la démonstration que la pression de radiation optique peut être contrôlée par l’hélicité du photon. Ce phénomène est ensuite utilisé, d’une part pour faire une démonstration de principe du tri de la chiralité matérielle via une approche optofluidique et d’autre part pour réaliser un piège optique tridimensionnel sensible à la chiralité de l’objet piégé.
Exploiting the angular momentum degree of freedom of light to control the mechanical effects that result from light-matter exchanges of linear momentum is an intriguing challenge that may open new routes towards enhanced optical manipulation of material systems. In this context, our work addresses the interplay between the chirality of matter and the chirality of optical fields. Experimentally, this is done by using cholesteric liquid crystal droplets interacting with circularly polarized light and we provide with theoretical developments to quantitatively support our observations. Our main result is the demonstration of optical radiation force controlled by the photon helicity. This phenomenon is then used to demonstrate the optofluidic sorting of material chirality and the helicity-dependent three-dimensional optical trapping of chiral liquid crystal microspheres.
Advisors/Committee Members: Brasselet, Etienne (thesis director).
Subjects/Keywords: Optomécanique; Piégeage et manipulation optique; Cristaux liquides; Moment angulaire de la lumière; Chiralité; Optofluidique; Optomechanics; Optical trapping and manipulation; Liquid crystals; Optical angular momentum; Chirality; Optofluidics
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APA ·
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MLA ·
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APA (6th Edition):
Tkachenko, G. (2014). Optical trapping and manipulation of chiral microspheres controlled by the photon helicity : Le piégeage et la manipulation optique de microsphères chiraux contrôlées par l'hélicité du photon. (Doctoral Dissertation). Bordeaux. Retrieved from http://www.theses.fr/2014BORD0102
Chicago Manual of Style (16th Edition):
Tkachenko, Georgiy. “Optical trapping and manipulation of chiral microspheres controlled by the photon helicity : Le piégeage et la manipulation optique de microsphères chiraux contrôlées par l'hélicité du photon.” 2014. Doctoral Dissertation, Bordeaux. Accessed March 04, 2021.
http://www.theses.fr/2014BORD0102.
MLA Handbook (7th Edition):
Tkachenko, Georgiy. “Optical trapping and manipulation of chiral microspheres controlled by the photon helicity : Le piégeage et la manipulation optique de microsphères chiraux contrôlées par l'hélicité du photon.” 2014. Web. 04 Mar 2021.
Vancouver:
Tkachenko G. Optical trapping and manipulation of chiral microspheres controlled by the photon helicity : Le piégeage et la manipulation optique de microsphères chiraux contrôlées par l'hélicité du photon. [Internet] [Doctoral dissertation]. Bordeaux; 2014. [cited 2021 Mar 04].
Available from: http://www.theses.fr/2014BORD0102.
Council of Science Editors:
Tkachenko G. Optical trapping and manipulation of chiral microspheres controlled by the photon helicity : Le piégeage et la manipulation optique de microsphères chiraux contrôlées par l'hélicité du photon. [Doctoral Dissertation]. Bordeaux; 2014. Available from: http://www.theses.fr/2014BORD0102

University of Texas – Austin
4.
Demergis, Vassili.
Ultra-precise manipulation and assembly of nanoparticles using three fundamental optical forces.
Degree: PhD, Physics, 2012, University of Texas – Austin
URL: http://hdl.handle.net/2152/35439
► The invention of the laser in 1960 opened the door for a myriad of studies on the interactions between light and matter. Eventually it was…
(more)
▼ The invention of the laser in 1960 opened the door for a myriad of studies on the interactions between light and matter. Eventually it was shown that highly focused laser beams could be used to con fine and manipulate matter in a controlled way, and these instruments were known as
optical traps. However, challenges remain as there is a delicate balance between object size, precision of control, laser power, and temperature that must be satisfied.
In Part I of this dissertation, I describe the development of two
optical trapping instruments which substantially extend the allowed parameter ranges. Both instruments utilize a standing wave
optical field to generate strong
optical gradient forces while minimizing the
optical scattering forces, thus dramatically improving
trapping efficiency. One instrument uses a cylinder lens to extend the
trapping region into a line focus, rather than a point focus, thereby confining objects to 1D motion. By translation of the cylinder lens, lateral scattering forces can be generated to transport objects along the 1D
trapping volume, and these scattering forces can be controlled independently of the
optical gradient forces. The second instrument uses a collimated beam to generate wide, planar
trapping regions which can con fine nanoparticles to 2D motion.
In Part II, I use these instruments to provide the first quantitative measurements of the
optical binding interaction between nanoparticles. I show that the
optical binding force can be over 20 times stronger than the
optical gradient force generated in typical
optical traps, and I map out the 2D
optical binding energy landscape between a pair of gold nanoparticles. I show how this ultra-strong
optical binding leads to the self-assembly of multiple nanoparticles into larger contactless clusters of well de ned geometry. I nally show that these clusters have a geometry dependent coupling to the external
optical field.
Advisors/Committee Members: Florin, Ernst-Ludwig (advisor), Shubeita, George T (committee member), Fink, Manfred (committee member), Makarov, Dmitrii E (committee member), Korgel, Brian A (committee member).
Subjects/Keywords: Transport; Sorting; Mixing; Gold; Optical matter; Radiation pressure; Physics; Optics; Forces; Biophysics; Lasers; Optical trapping; Manipulation; Optical binding; Standing wave; Fractionation; Gradient force; Scattering force; Energy landscape; Nanoparticles; Self-assembly
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Demergis, V. (2012). Ultra-precise manipulation and assembly of nanoparticles using three fundamental optical forces. (Doctoral Dissertation). University of Texas – Austin. Retrieved from http://hdl.handle.net/2152/35439
Chicago Manual of Style (16th Edition):
Demergis, Vassili. “Ultra-precise manipulation and assembly of nanoparticles using three fundamental optical forces.” 2012. Doctoral Dissertation, University of Texas – Austin. Accessed March 04, 2021.
http://hdl.handle.net/2152/35439.
MLA Handbook (7th Edition):
Demergis, Vassili. “Ultra-precise manipulation and assembly of nanoparticles using three fundamental optical forces.” 2012. Web. 04 Mar 2021.
Vancouver:
Demergis V. Ultra-precise manipulation and assembly of nanoparticles using three fundamental optical forces. [Internet] [Doctoral dissertation]. University of Texas – Austin; 2012. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/2152/35439.
Council of Science Editors:
Demergis V. Ultra-precise manipulation and assembly of nanoparticles using three fundamental optical forces. [Doctoral Dissertation]. University of Texas – Austin; 2012. Available from: http://hdl.handle.net/2152/35439

University of St Andrews
5.
Nylk, Jonathan.
Advanced light-sheet and structured illumination microscopy techniques for neuroscience and disease diagnosis.
Degree: PhD, 2016, University of St Andrews
URL: http://hdl.handle.net/10023/10842
► Optical microscopy is a cornerstone of biomedical research. Advances in optical techniques enable specific, high resolution, sterile, and biologically compatible imaging. In particular, beam shaping…
(more)
▼ Optical microscopy is a cornerstone of biomedical research. Advances in optical techniques enable specific, high resolution, sterile, and biologically compatible imaging. In particular, beam shaping has been used to tailor microscopy techniques to enhance microscope performance. The aim of this Thesis is to investigate the use of novel beam shaping techniques in emerging optical microscopy methods, and to apply these methods in biomedicine. To overcome the challenges associated with high resolution imaging of large specimens, the use of Airy beams and related techniques are applied to light-sheet microscopy. This approach increases the field-of-view that can be imaged at high resolution by over an order of magnitude compared to standard Gaussian beam based light-sheet microscopy, has reduced phototoxicity, and can be implemented with a low-cost optical system. Advanced implementations show promise for imaging at depth within turbid tissue, in particular for neuroscience. Super-resolution microscopy techniques enhance the spatial resolution of optical methods. Structured illumination microscopy is investigated as an alternative for electron microscopy in disease diagnosis, capable of visualising pathologically relevant features of kidney disease. Separately, compact optical manipulation methods are developed with the aim of adding functionality to super-resolution techniques.
Subjects/Keywords: 610.28; Microscopy; Beam shaping; Wavefront shaping; Fluorescence; Light-sheet microscopy; LSM; Structured illumination microscopy; SIM; Optical manipulation; Optical trapping; Airy beam; Bessel beam; Gaussiam beam; Physics; QH207.N8
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Nylk, J. (2016). Advanced light-sheet and structured illumination microscopy techniques for neuroscience and disease diagnosis. (Doctoral Dissertation). University of St Andrews. Retrieved from http://hdl.handle.net/10023/10842
Chicago Manual of Style (16th Edition):
Nylk, Jonathan. “Advanced light-sheet and structured illumination microscopy techniques for neuroscience and disease diagnosis.” 2016. Doctoral Dissertation, University of St Andrews. Accessed March 04, 2021.
http://hdl.handle.net/10023/10842.
MLA Handbook (7th Edition):
Nylk, Jonathan. “Advanced light-sheet and structured illumination microscopy techniques for neuroscience and disease diagnosis.” 2016. Web. 04 Mar 2021.
Vancouver:
Nylk J. Advanced light-sheet and structured illumination microscopy techniques for neuroscience and disease diagnosis. [Internet] [Doctoral dissertation]. University of St Andrews; 2016. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/10023/10842.
Council of Science Editors:
Nylk J. Advanced light-sheet and structured illumination microscopy techniques for neuroscience and disease diagnosis. [Doctoral Dissertation]. University of St Andrews; 2016. Available from: http://hdl.handle.net/10023/10842
6.
Nilsson, Daniel.
Development of Next-Generation Optical Tweezers : The New Swiss Army Knife of Biophysical and Biomechanical Research.
Degree: Physics, 2020, Umeå University
URL: http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-172362
► In a time when microorganisms are controlling the world, research in biology is more relevant than ever and this requires some powerful instruments. Optical…
(more)
▼ In a time when microorganisms are controlling the world, research in biology is more relevant than ever and this requires some powerful instruments. Optical tweezers use a focused laser beam to manipulate and probe objects on the nano- and microscale. This allows for the exploration of a miniature world at the border between biology, chemistry and physics. New methods for biophysical and physicochemical measurements are continuously being developed and at Umeå University there is a need for a new system that combines several of these methods. This would truly be the new Swiss army knife of biophysical and biomechanical research, extending their reach in the world of optical tweezing. My ambition with this project is to design and construct a robust system that incorporates optical trapping with high-precision force measurements and Raman spectroscopy, as well as introducing the possibility of generating multiple traps by using a spatial light modulator (SLM). The proposed design incorporates four different lasers and a novel combination of signal detection techniques. To allow for precise control of the systems components and laser beams, I designed and constructed motorized opto-mechanical components. These are controlled by an in-house developed software that handles data processing and signal analysis, while also providing a user interface for the system. The components include, motorized beam blockers and optical attenuators, which were developed using commonly available 3D printing techniques and electronic controllers. By designing the system from scratch, I could eliminate the known weaknesses of conventional systems and allow for a modular design where components can be added easily. The system is divided into two parts, a laser breadboard and a main breadboard. The former contains all the equipment needed to generate and control the laser beams, which are then coupled through optical fibers to the latter. This contains the components needed to move the optical trap inside the sample chamber, while performing measurements and providing user feedback. Construction and testing was done for one sub-system at a time, while the lack of time required a postponement for the implementation of Raman and SLM. The system performance was verified through Allan variance stability tests and the results were compared with other optical tweezers setups. The results show that the system follows the thermal limit for averaging times (τ) up to ~1 s when disturbances had been eliminated, which is similar to other systems. However, we could also show a decrease in variance all the way to τ = 2000 s, which is exceptionally good and not found in conventional systems. The force-resolution was determined to be on the order of femtonewtons, which is also exceptionally good. Thus, I conclude that this optical tweezers setup could lie as a solid foundation for future development and research in biological science at Umeå University for years to come.
Subjects/Keywords: optical tweezers; optical fiber tweezers; optical fiber; optical trapping; manipulation; optical force; cell trapping; biophysical; physicochemical; biomechanical; research; next-generation; raman spectroscopy; holographic optical tweezers; Medical Laboratory and Measurements Technologies; Medicinsk laboratorie- och mätteknik; Biochemistry and Molecular Biology; Biokemi och molekylärbiologi; Atom and Molecular Physics and Optics; Atom- och molekylfysik och optik; Physical Chemistry; Fysikalisk kemi
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Nilsson, D. (2020). Development of Next-Generation Optical Tweezers : The New Swiss Army Knife of Biophysical and Biomechanical Research. (Thesis). Umeå University. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-172362
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Nilsson, Daniel. “Development of Next-Generation Optical Tweezers : The New Swiss Army Knife of Biophysical and Biomechanical Research.” 2020. Thesis, Umeå University. Accessed March 04, 2021.
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-172362.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Nilsson, Daniel. “Development of Next-Generation Optical Tweezers : The New Swiss Army Knife of Biophysical and Biomechanical Research.” 2020. Web. 04 Mar 2021.
Vancouver:
Nilsson D. Development of Next-Generation Optical Tweezers : The New Swiss Army Knife of Biophysical and Biomechanical Research. [Internet] [Thesis]. Umeå University; 2020. [cited 2021 Mar 04].
Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-172362.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Nilsson D. Development of Next-Generation Optical Tweezers : The New Swiss Army Knife of Biophysical and Biomechanical Research. [Thesis]. Umeå University; 2020. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-172362
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of California – Santa Cruz
7.
Leake, Kaelyn Danielle.
On-Chip Particle Trapping and Manipulation.
Degree: Electrical Engineering, 2015, University of California – Santa Cruz
URL: http://www.escholarship.org/uc/item/35m9317s
► The ability to control and manipulate the world around us is human nature. Humans and our ancestors have used tools for millions of years. Only…
(more)
▼ The ability to control and manipulate the world around us is human nature. Humans and our ancestors have used tools for millions of years. Only in recent years have we been able to control objects at such small levels. In order to understand the world around us it is frequently necessary to interact with the biological world. Optical trapping and manipulation offer a non-invasive way to move, sort and interact with particles and cells to see how they react to the world around them. Optical tweezers are ideal in their abilities but they require large, non-portable, and expensive setups limiting how and where we can use them. A cheap portable platform is required in order to have optical manipulation reach its full potential. On-chip technology offers a great solution to this challenge. We focused on the Liquid-Core Anti-Resonant Reflecting Optical Waveguide (liquid-core ARROW) for our work. The ARROW is an ideal platform, which has anti-resonant layers which allow light to be guided in liquids, allowing for particles to easily be manipulated. It is manufactured using standard silicon manufacturing techniques making it easy to produce. The planner design makes it easy to integrate with other technologies. Initially I worked to improve the ARROW chip by reducing the intersection losses and by reducing the fluorescence and background on the ARROW chip. The ARROW chip has already been used to trap and push particles along its channel but here I introduce several new methods of particle trapping and manipulation on the ARROW chip. Traditional two beam traps use two counter propagating beams. A trapping scheme that uses two orthogonal beams which counter to first instinct allow for trapping at their intersection is introduced. This scheme is thoroughly predicted and analyzed using realistic conditions. Simulations of this method were done using a program which looks at both the fluidics and optical sources to model complex situations. These simulations were also used to model and predict a sorting method which combines fluid flow with a single optical source to automatically sort dielectric particles by size in waveguide networks. These simulations were shown to be accurate when repeated on-chip. Lastly I introduce a particle trapping technique that uses Multimode Interference(MMI) patterns in order to trap multiple particles at once. The location of the traps can be adjusted as can the number of trapping location by changing the input wavelength. By changing the wavelength back and forth between two values this MMI can be used to pass a particle down the channel like a conveyor belt.
Subjects/Keywords: Optics; Nanotechnology; ARROW; lab-on-chip; manipulation; trapping
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Leake, K. D. (2015). On-Chip Particle Trapping and Manipulation. (Thesis). University of California – Santa Cruz. Retrieved from http://www.escholarship.org/uc/item/35m9317s
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Leake, Kaelyn Danielle. “On-Chip Particle Trapping and Manipulation.” 2015. Thesis, University of California – Santa Cruz. Accessed March 04, 2021.
http://www.escholarship.org/uc/item/35m9317s.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Leake, Kaelyn Danielle. “On-Chip Particle Trapping and Manipulation.” 2015. Web. 04 Mar 2021.
Vancouver:
Leake KD. On-Chip Particle Trapping and Manipulation. [Internet] [Thesis]. University of California – Santa Cruz; 2015. [cited 2021 Mar 04].
Available from: http://www.escholarship.org/uc/item/35m9317s.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Leake KD. On-Chip Particle Trapping and Manipulation. [Thesis]. University of California – Santa Cruz; 2015. Available from: http://www.escholarship.org/uc/item/35m9317s
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Illinois – Urbana-Champaign
8.
Shenoy, Anish.
Development and application of the stokes trap for measurement of interparticle interactions.
Degree: PhD, Mechanical Engineering, 2017, University of Illinois – Urbana-Champaign
URL: http://hdl.handle.net/2142/98167
► The ability to trap and control single particles in free solution has led to major advances in science and engineering. Common methods for particle trapping…
(more)
▼ The ability to trap and control single particles in free solution has led to major advances in science and engineering. Common methods for particle
trapping and
manipulation often rely on
optical, magnetic, acoustic, or electric forces. However, the vast majority of these methods critically depend on the target particle possessing specific physical properties such as index of refraction or surface charge. In this research, we have designed and built a Stokes trap, which allows for the
manipulation and control of an arbitrary number of arbitrary type particles using only fluid flow. In this way, we have effectively constructed a `smart microfluidic device' by coupling feedback control with microfluidics, thereby enabling new routes for the fluidic-directed assembly of particles. This work is comprised of three distinct but interrelated efforts towards the precision
trapping and
manipulation of multiple particles using fluid flow. In the first project, the control algorithm for a microfluidic process is extensively studied for confining a single particle in solution. Here, we study the response of trapped particles actuated using a combination of proportional, integral, and derivative controllers (PID control), which extends beyond our prior work where we utilized a simple proportional controller for 2-D
manipulation of particles in free solution. We investigate the effect of controller gains, flow rate, and feedback response times on the robustness of
trapping, using a combination of simulation and experimental studies. In the second project, we present the development and application of the Stokes Trap, which is a multiplexed microfluidic method for arbitrary
manipulation of an arbitrary number of particles in solution. We demonstrate simultaneous
manipulation of two particles in a simple microfluidic device, and also achieve fluidic directed assembly of multiple particles in solution. In the third project, the Stokes trap is used to implement and experimentally demonstrate trajectory control using fluidic
trapping, wherein particles are controlled by a path-following framework that improves the precision and the speed of
manipulation of particles along arbitrary paths. An extended Kalman filter is also implemented, which effectively reduces the offset due to unmodeled phenomena during particle
trapping. Finally, these techniques are leveraged to demonstrate the direct determination of solvent-mediated hydrodynamic interactions (HI) between two freely suspended colloidal particles in flow. From a broad perspective, this work provides a robust framework for studying fundamental interactions between particles or for guiding the directed assembly of materials.
Advisors/Committee Members: Schroeder, Charles M (advisor), Hilgenfeldt, Sascha (Committee Chair), Rao, Christopher V (committee member), Chen, Qian (committee member).
Subjects/Keywords: Microfluidics; Hydrodynamics; Directed assembly; Stokes flow; Particle manipulation; Particle trapping
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
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APA (6th Edition):
Shenoy, A. (2017). Development and application of the stokes trap for measurement of interparticle interactions. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/98167
Chicago Manual of Style (16th Edition):
Shenoy, Anish. “Development and application of the stokes trap for measurement of interparticle interactions.” 2017. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed March 04, 2021.
http://hdl.handle.net/2142/98167.
MLA Handbook (7th Edition):
Shenoy, Anish. “Development and application of the stokes trap for measurement of interparticle interactions.” 2017. Web. 04 Mar 2021.
Vancouver:
Shenoy A. Development and application of the stokes trap for measurement of interparticle interactions. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2017. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/2142/98167.
Council of Science Editors:
Shenoy A. Development and application of the stokes trap for measurement of interparticle interactions. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2017. Available from: http://hdl.handle.net/2142/98167
9.
Baresch, Diego.
Pince acoustique : piégeage et manipulation d'un objet par pression de radiation d'une onde progressive : Acoustical tweezers : trapping and manipulation of small objects with the radiation pressure of progressive sound waves.
Degree: Docteur es, Acoustique physique, 2014, Université Pierre et Marie Curie – Paris VI
URL: http://www.theses.fr/2014PA066542
► La pression de radiation acoustique est la force moyenne qu'une onde peut exercer sur un obstacle. Initialement, la faible manifestation de cette force ne suggérait…
(more)
▼ La pression de radiation acoustique est la force moyenne qu'une onde peut exercer sur un obstacle. Initialement, la faible manifestation de cette force ne suggérait pas d'applications potentielles. Néanmoins, avec l'avènement de sources acoustiques de haute puissance, il a rapidement été envisagé de manipuler de petits objets à distance par pression de radiation. Depuis, c'est via l'excitation d'ondes stationnaires dans des cavités que cette méthodologie connait son essor. Parallèlement, la pression de radiation de la lumière a rapidement permis de piéger et de manipuler des petits objets. Grâce à un laser fortement focalisé, la pince optique a donné une grande flexibilité aux techniques de manipulation sans contact et est devenue un outil fondamental pour de nombreuses disciplines scientifiques. Cependant, les faibles forces développées, les importantes intensités lumineuses requises et la petite taille des objets sont d'importantes limites tout particulièrement pour leur application en biologie.A l'heure actuelle, il n'existe pas l'équivalent de la pince optique en acoustique utilisant un unique faisceau. Le travail présenté donne un ensemble d'éléments théoriques et expérimentaux profitables pour la compréhension de la pression de radiation en acoustique et le dimensionnement d'une pince acoustique utilisant un unique faisceau ultrasonore : le vortex acoustique. Ce travail esquisse l'ébauche d'une nouvelle méthode de manipulation sans contact donnant une véritable dextérité de préhension. Les faibles intensités nécessaires associées aux larges forces développées sauront se montrer attractives pour imaginer un large panel de nouvelles applications scientifiques.
As an acoustic wave impinges an obstacle, a mean force is exerted on its surface. This so-called radiation pressure arises from the non linear interaction between the wave and the object.The early history of this force did not suggest any application of such a feeble effect. Nevertheless, as technological advances improved the prospects of new powerful sound sources, it was rapidly considered to use the acoustic radiation pressure as a mean of non-contact manipulation of small objects. Ever since, standing wave schemes excited in cavities has been the preferred strategy that is becoming considerably popular.In the same time, the radiation pressure of light was also recognised to trap and manipulate very small objects. Using a single focused laser beam, optical tweezers brought a great dexterity to non contact manipulation techniques and rapidly grew to become a fundamental tool in many scientific fields. However, the minuteness of the force, the high intensities required and the smallness of trappable objects are well-known limitations in particular for biological applications.Although optics and acoustics have shown many similarities, an acoustical analogue to optical tweezers using a single beam is yet to be demonstrated. Theoretical and experimental efforts are presented here and shed light on the underpinning mechanisms of single-beam acoustical…
Advisors/Committee Members: Marchiano, Régis (thesis director), Thomas, Jean-Louis (thesis director).
Subjects/Keywords: Pression de radiation; Manipulation sans-Contact; Acoustique; Lévitation; Vortex acoustique; Ultrasons; Trapping with the radiation pressure; Non contact manipulation; 534.5
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Baresch, D. (2014). Pince acoustique : piégeage et manipulation d'un objet par pression de radiation d'une onde progressive : Acoustical tweezers : trapping and manipulation of small objects with the radiation pressure of progressive sound waves. (Doctoral Dissertation). Université Pierre et Marie Curie – Paris VI. Retrieved from http://www.theses.fr/2014PA066542
Chicago Manual of Style (16th Edition):
Baresch, Diego. “Pince acoustique : piégeage et manipulation d'un objet par pression de radiation d'une onde progressive : Acoustical tweezers : trapping and manipulation of small objects with the radiation pressure of progressive sound waves.” 2014. Doctoral Dissertation, Université Pierre et Marie Curie – Paris VI. Accessed March 04, 2021.
http://www.theses.fr/2014PA066542.
MLA Handbook (7th Edition):
Baresch, Diego. “Pince acoustique : piégeage et manipulation d'un objet par pression de radiation d'une onde progressive : Acoustical tweezers : trapping and manipulation of small objects with the radiation pressure of progressive sound waves.” 2014. Web. 04 Mar 2021.
Vancouver:
Baresch D. Pince acoustique : piégeage et manipulation d'un objet par pression de radiation d'une onde progressive : Acoustical tweezers : trapping and manipulation of small objects with the radiation pressure of progressive sound waves. [Internet] [Doctoral dissertation]. Université Pierre et Marie Curie – Paris VI; 2014. [cited 2021 Mar 04].
Available from: http://www.theses.fr/2014PA066542.
Council of Science Editors:
Baresch D. Pince acoustique : piégeage et manipulation d'un objet par pression de radiation d'une onde progressive : Acoustical tweezers : trapping and manipulation of small objects with the radiation pressure of progressive sound waves. [Doctoral Dissertation]. Université Pierre et Marie Curie – Paris VI; 2014. Available from: http://www.theses.fr/2014PA066542

University of St. Andrews
10.
Marchington, Robert F.
Applications of microfluidic chips in optical manipulation & photoporation
.
Degree: 2010, University of St. Andrews
URL: http://hdl.handle.net/10023/1633
► Integration and miniaturisation in electronics has undoubtedly revolutionised the modern world. In biotechnology, emerging lab-on-a-chip (LOC) methodologies promise all-integrated laboratory processes, to perform complete biochemical…
(more)
▼ Integration and miniaturisation in electronics has undoubtedly revolutionised the
modern world. In biotechnology, emerging lab-on-a-chip (LOC) methodologies promise all-integrated laboratory processes, to perform complete biochemical or medical
synthesis and analysis encapsulated on small microchips. The integration of electrical,
optical and physical sensors, and control devices, with fluid handling, is creating
a new class of functional chip-based systems. Scaled down onto a chip, reagent and
sample consumption is reduced, point-of-care or in-the-field usage is enabled through
portability, costs are reduced, automation increases the ease of use, and favourable
scaling laws can be exploited, such as improved fluid control. The capacity to manipulate single cells on-chip has applications across the life sciences, in biotechnology,
pharmacology, medical diagnostics and drug discovery.
This thesis explores multiple applications of
optical manipulation within microfluidic chips. Used in combination with microfluidic systems, optics adds powerful
functionalities to emerging LOC technologies. These include particle management
such as immobilising, sorting, concentrating, and transportation of cell-sized objects,
along with sensing, spectroscopic interrogation, and cell treatment.
The work in this thesis brings several key applications of
optical techniques
for manipulating and porating cell-sized microscopic particles to within microfluidic
chips. The fields of
optical trapping,
optical tweezers and
optical sorting are reviewed
in the context of lab-on-a-chip application, and the physics of the laminar fluid flow
exhibited at this size scale is detailed. Microfluidic chip fabrication methods are
presented, including a robust method for the introduction of
optical fibres for laser
beam delivery, which is demonstrated in a dual-beam
optical trap chip and in
optical
chromatography using photonic crystal fibre. The use of a total internal reflection microscope objective lens is utilised in a
novel demonstration of propelling particles within fluid flow. The size and refractive
index dependency is modelled and experimentally characterised, before presenting
continuous passive
optical sorting of microparticles based on these intrinsic
optical
properties, in a microfluidic chip.
Finally, a microfluidic system is utilised in the delivery of mammalian cells to a
focused femtosecond laser beam for continuous, high throughput photoporation. The
optical injection efficiency of inserting a fluorescent dye is determined and the cell
viability is evaluated. This could form the basis for ultra-high throughput, efficient
transfection of cells, with the advantages of single cell treatment and unrivalled
viability using this
optical technique.
Advisors/Committee Members: Dholakia, Kishan (advisor).
Subjects/Keywords: Microfluidics;
Optical trapping;
Passive optical sorting;
Optical manipulation;
Lab-on-a-chip;
Photoporation;
Optical injection;
PDMS;
Soft lithography;
Evanescent waves;
Total internal reflection;
TIRF objective lens;
Dual beam trap
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Marchington, R. F. (2010). Applications of microfluidic chips in optical manipulation & photoporation
. (Thesis). University of St. Andrews. Retrieved from http://hdl.handle.net/10023/1633
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Marchington, Robert F. “Applications of microfluidic chips in optical manipulation & photoporation
.” 2010. Thesis, University of St. Andrews. Accessed March 04, 2021.
http://hdl.handle.net/10023/1633.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Marchington, Robert F. “Applications of microfluidic chips in optical manipulation & photoporation
.” 2010. Web. 04 Mar 2021.
Vancouver:
Marchington RF. Applications of microfluidic chips in optical manipulation & photoporation
. [Internet] [Thesis]. University of St. Andrews; 2010. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/10023/1633.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Marchington RF. Applications of microfluidic chips in optical manipulation & photoporation
. [Thesis]. University of St. Andrews; 2010. Available from: http://hdl.handle.net/10023/1633
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

KTH
11.
Leuthner, Moritz.
Improving cell secretome analysis and bacteria evolution by means of acoustophoresis.
Degree: Biotechnology and Health (CBH), 2020, KTH
URL: http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-285985
► In both, cell secretome analysis and bacteria evolution, controlled handling of particles with a few to sub-micrometers in size and media exchange are inevitable…
(more)
▼ In both, cell secretome analysis and bacteria evolution, controlled handling of particles with a few to sub-micrometers in size and media exchange are inevitable in order to investigate body fluid’s proteins or change the surrounding culture conditions for pivoted evolution. Typically, nanofiltration and ultra-centrifugation are employed which can lead to cell damage, need large sample volumes and have a high sample loss. Using contactless and label-free acoustic cell manipulation, disadvantages of other magnetic, dielectric or hydrodynamic methods can be avoided. Here, a novel design using acoustic forces for small particle trapping and media exchange is thoroughly numerically investigated including first- and second-order acoustic effects. The device comprises parallel aligned medium and air channels separated by a thin wall. Particle trapping occurs at this thin wall. The medium channel dimensions (height and width) and thin wall thickness are optimized with respect to trapping forces. Thinnest walls are preferable and an aspect ratio of 0.8. First preliminary experimental variation with polystyrene particles showed good agreement with the simulations. Thereby the particle trapping efficiency is evaluated under quiescent flow conditions. For particle trapping, a device with a channel height of 290μm and an aspect ratio of 0.7 is superior which supports the numerical results. Finally, medium exchange of E. coli bacteria is demonstrated with best results for a device with a channel height of 450μm and an aspect ratio of 0.8 showing that 13.4% of the initial bacteria were released after medium exchange which can be used for further processing.
Subjects/Keywords: acoustophoresis; acoustofluidic; lab-on-a-chip; acoustic streaming; acoustic radiation force; particle trapping; particle washing; bulk acoustic waves; BAW; media exchange; cell manipulation; Medical Engineering; Medicinteknik
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Leuthner, M. (2020). Improving cell secretome analysis and bacteria evolution by means of acoustophoresis. (Thesis). KTH. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-285985
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Leuthner, Moritz. “Improving cell secretome analysis and bacteria evolution by means of acoustophoresis.” 2020. Thesis, KTH. Accessed March 04, 2021.
http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-285985.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Leuthner, Moritz. “Improving cell secretome analysis and bacteria evolution by means of acoustophoresis.” 2020. Web. 04 Mar 2021.
Vancouver:
Leuthner M. Improving cell secretome analysis and bacteria evolution by means of acoustophoresis. [Internet] [Thesis]. KTH; 2020. [cited 2021 Mar 04].
Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-285985.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Leuthner M. Improving cell secretome analysis and bacteria evolution by means of acoustophoresis. [Thesis]. KTH; 2020. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-285985
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
12.
Vieira, Gregory Butler.
Patterned Magnetic Structures for Micro-/Nanoparticle and
Cell Manipulation.
Degree: PhD, Physics, 2012, The Ohio State University
URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1354567338
► Remote manipulation of fluid-borne magnetic particles on a surface is useful to probe, assemble, and sort microscale and nanoscale objects. By patterning magnetic structures…
(more)
▼ Remote
manipulation of fluid-borne magnetic
particles on a surface is useful to probe, assemble, and sort
microscale and nanoscale objects. By patterning magnetic structures
in shapes designed to exploit local heterogeneities in thin film
magnetization, we have demonstrated effective
trapping mechanisms
for superparamagnetic micro- and nanoparticles. The features
necessary for
trapping are shown to arise at domain walls or
indentations in microscale and smaller magnetic wires, at the
periphery of magnetized disks, and at corners of magnetized
triangles. Weak (<150 Oe) in- and out-of-plane
external magnetic fields modify the energy landscape of the trapped
particles, allowing for the objects to be remotely maneuvered along
selected routes across the surface. The mechanism is multiplexed,
allowing for simultaneous
manipulation of many trapped particles,
and their motion is directed using a handheld user interface.
Particles are able to be transported over hundreds of micrometers
with velocities of upwards of 200 μm/s and average forces of up to
hundreds of picoNewtons. The magnetic fields,
their spatial distribution, and resulting forces are estimated by
modeling magnetization of the patterned structures using
micromagnetic simulation or by approximating the traps as point
sources of fields. The quality of these models and their relevance
for describing particle
manipulation under the experimental
conditions is discussed. The applicability of
these techniques is demonstrated for various biological,
biomolecular, and nanoscale systems. Binding of magnetic particles
to cells allows for guided cell transport. Composite micelle
nanostructures, only tens of nm across, are simultaneously trapped
and maneuvered magnetically and tracked fluorescently, despite
their small size. The implications for use of this technology in
lab-on-chip devices are discussed.
Advisors/Committee Members: Sooryakumar, Ratnasingham (Advisor).
Subjects/Keywords: Physics; Patterned Magnetic Structures; Microparticles; Nanoparticles; Particle Trapping and Manipulation; Cell Trapping; Domain Walls
…44
3.4 Integrated Optical-Magnetic Tweezers for Cell Manipulation… …61
4.4 Triangular Elements for Particle Trapping and Manipulation… …Optical tweezers, atomic
force microscope (AFM) manipulation, and magnetic tweezers… …patterned
ferromagnetic structures. These new technologies allow for the trapping and
manipulation… …discuss three
techniques: optical tweezers, atomic force microscopy (AFM) manipulation…
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Vieira, G. B. (2012). Patterned Magnetic Structures for Micro-/Nanoparticle and
Cell Manipulation. (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1354567338
Chicago Manual of Style (16th Edition):
Vieira, Gregory Butler. “Patterned Magnetic Structures for Micro-/Nanoparticle and
Cell Manipulation.” 2012. Doctoral Dissertation, The Ohio State University. Accessed March 04, 2021.
http://rave.ohiolink.edu/etdc/view?acc_num=osu1354567338.
MLA Handbook (7th Edition):
Vieira, Gregory Butler. “Patterned Magnetic Structures for Micro-/Nanoparticle and
Cell Manipulation.” 2012. Web. 04 Mar 2021.
Vancouver:
Vieira GB. Patterned Magnetic Structures for Micro-/Nanoparticle and
Cell Manipulation. [Internet] [Doctoral dissertation]. The Ohio State University; 2012. [cited 2021 Mar 04].
Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1354567338.
Council of Science Editors:
Vieira GB. Patterned Magnetic Structures for Micro-/Nanoparticle and
Cell Manipulation. [Doctoral Dissertation]. The Ohio State University; 2012. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1354567338
13.
Chong, Kwitae.
Particle Manipulation in Viscous Streaming.
Degree: Mechanical Engineering, 2013, UCLA
URL: http://www.escholarship.org/uc/item/27h0j2b0
► The necessity of micromanipulation to separate, focus and transport discrete objects on a microscopic scale has emerged in recent years in areas from assisted fertilization…
(more)
▼ The necessity of micromanipulation to separate, focus and transport discrete objects on a microscopic scale has emerged in recent years in areas from assisted fertilization to precision machining. This work explores the manipulation of microparticles suspended in viscous streaming flow. Streaming is a steady large-scale circulatory flow generated by the nonlinear interaction of the primary oscillatory motion. The first part of the study focuses on particle transport and trapping in the streaming flow generated by a single oscillating cylinder. The streaming flow is obtained by asymptotic expansion from previous work and the resulting velocity field is used to integrate the Maxey-Riley equation with the Saffman lift for the motion of an inertial spherical particle immersed in this flow. It is found that inertial particles spiral inward and become trapped inside one of the four streaming cells established by the cylinder oscillation, regardless of the particle size, density and flow Reynolds number. It is shown that the Faxen correction terms divert the particles from the fluid particle trajectories, and once diverted, the Saffman lift force is most responsible for effecting the inward motion and trapping. Results compare favorably with previous experiments.We extend this study to various arrangements of oscillating probes. High fidelity computations are used to simulate the flow field to capture particle transport. It is shown that, by controlling the sequence of starting and stopping the oscillation of individual probes, inertial particles can be transported in a predictable manner between trapping points. In order to reduce the considerable expense of generating the flow field, we also explore the use of steady Stokes flow to serve as an approximate surrogate for the flow between probes. The boundary conditions for this flow are obtained by matching with the inner Stokes layer solution in the asymptotic expansion for small amplitude. Finally, the practical characteristics of transport by streaming are discussed.Overall, this study reveals that viscous streaming is an effective mechanism with which to manipulate small particles. To the best of my knowledge, this work is the first to investigate inertial particle trapping and transport in viscous streaming theoretically and computationally.
Subjects/Keywords: Mechanical engineering; inertial particle transport; inertial particle trapping; Maxey-Riely equation; particle manipulation; viscous streaming
…Inertial Particle Trapping . . . . . . . . . . . . . . . . . . . . . . .
51
4.1
Inertial… …Particle Trapping . . . . . . . . . . . . . . . . . . . . . .
51
4.2
Inertial particle… …Trapping Mechanism . . . . . . . . . . . . . . . .
55
4.3
Inertial particle trapping speed… …4.3
53
Comparison of trapping position from current results (red squares)
and… …0.175. (b) Trapping timescale dependence
on a/R, for Re = 40, ρp /ρf = 1. This figure…
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Chong, K. (2013). Particle Manipulation in Viscous Streaming. (Thesis). UCLA. Retrieved from http://www.escholarship.org/uc/item/27h0j2b0
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Chong, Kwitae. “Particle Manipulation in Viscous Streaming.” 2013. Thesis, UCLA. Accessed March 04, 2021.
http://www.escholarship.org/uc/item/27h0j2b0.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Chong, Kwitae. “Particle Manipulation in Viscous Streaming.” 2013. Web. 04 Mar 2021.
Vancouver:
Chong K. Particle Manipulation in Viscous Streaming. [Internet] [Thesis]. UCLA; 2013. [cited 2021 Mar 04].
Available from: http://www.escholarship.org/uc/item/27h0j2b0.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Chong K. Particle Manipulation in Viscous Streaming. [Thesis]. UCLA; 2013. Available from: http://www.escholarship.org/uc/item/27h0j2b0
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
14.
McLean, Adrienne.
Understanding behaviour to improve trapping success of invasive Sea Lamprey.
Degree: MS, Department of Integrative Biology, 2015, University of Guelph
URL: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/8637
► Invasive species have large ecological and economic costs. Trapping could be used for effective control. I used underwater video to monitor behaviour of invasive Sea…
(more)
▼ Invasive species have large ecological and economic costs.
Trapping could be used for effective control. I used underwater video to monitor behaviour of invasive Sea Lamprey at traps located at a hydroelectric dam. I tested if few lamprey enter traps because high discharge from the dam prevented them from reaching openings, conspecifics deterred them from entering, and if more time spent at traps increased entrance rates. High discharge and conspecifics did not prevent lamprey from reaching and entering traps, and more time at traps increased entrance rates. Second, I collected lamprey from the field and assayed their behaviour in the lab to test if some lamprey were more vulnerable to
trapping due to personality differences. Trapped lamprey reduced their activity when a predator cue was added compared to lamprey captured by electrofishing. Control rooted in behavioural understanding is a promising management option if these behaviours can be exploited for
trapping.
Advisors/Committee Members: McLaughlin, Robert (advisor).
Subjects/Keywords: Invasive species; sea lamprey; animal behaviour; personality; discharge manipulation; trapping; control; management
…Trapping is an attractive form of invasive species control for animals. It entails removing… …Trapping has been used as a successful form of control for some invasive species, such
as the… …of
individuals captured from a population (trapping efficiency) has been low, as… …behaviour of a species may lead to increased trapping efficiency if
behaviour can be exploited by… …trapping (Cooke et al. 2007).
My thesis addressed explanations for why the probability…
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
McLean, A. (2015). Understanding behaviour to improve trapping success of invasive Sea Lamprey. (Masters Thesis). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/8637
Chicago Manual of Style (16th Edition):
McLean, Adrienne. “Understanding behaviour to improve trapping success of invasive Sea Lamprey.” 2015. Masters Thesis, University of Guelph. Accessed March 04, 2021.
https://atrium.lib.uoguelph.ca/xmlui/handle/10214/8637.
MLA Handbook (7th Edition):
McLean, Adrienne. “Understanding behaviour to improve trapping success of invasive Sea Lamprey.” 2015. Web. 04 Mar 2021.
Vancouver:
McLean A. Understanding behaviour to improve trapping success of invasive Sea Lamprey. [Internet] [Masters thesis]. University of Guelph; 2015. [cited 2021 Mar 04].
Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/8637.
Council of Science Editors:
McLean A. Understanding behaviour to improve trapping success of invasive Sea Lamprey. [Masters Thesis]. University of Guelph; 2015. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/8637

Vrije Universiteit Amsterdam
15.
Stas, R.J.W.
Trapping fermionic and bosonic helium atoms
.
Degree: 2005, Vrije Universiteit Amsterdam
URL: http://hdl.handle.net/1871/9015
► This thesis presents experimental and theoretical work performed at the Laser Centre of the Vrije Universiteit in Amsterdam to study laser-cooled metastable triplet helium atoms.…
(more)
▼ This thesis presents experimental and theoretical work performed at the Laser Centre of the Vrije Universiteit in Amsterdam to study laser-cooled metastable triplet helium atoms. Samples containing about 3x108 helium atoms-either fermionic helium-3 atoms, bosonic helium-4 atoms or mixtures thereof-are cooled to a temperature around 1 mK and form the starting point of the presented studies. The studies include an investigation of cold ionizing collisions in the absence of resonant light, an investigation of magneto-optical trapping with ultraviolet light, a feasibility study of an atomic fountain clock based on metastable helium-3 atoms and the first demonstration of magneto-optical trapping of an isotopic mixture of metastable helium atoms.
Subjects/Keywords: Laser cooling and trapping of fermionic 3He atoms;
Atomic collision processes;
Atom manipulation;
Frequency standards
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APA (6th Edition):
Stas, R. J. W. (2005). Trapping fermionic and bosonic helium atoms
. (Doctoral Dissertation). Vrije Universiteit Amsterdam. Retrieved from http://hdl.handle.net/1871/9015
Chicago Manual of Style (16th Edition):
Stas, R J W. “Trapping fermionic and bosonic helium atoms
.” 2005. Doctoral Dissertation, Vrije Universiteit Amsterdam. Accessed March 04, 2021.
http://hdl.handle.net/1871/9015.
MLA Handbook (7th Edition):
Stas, R J W. “Trapping fermionic and bosonic helium atoms
.” 2005. Web. 04 Mar 2021.
Vancouver:
Stas RJW. Trapping fermionic and bosonic helium atoms
. [Internet] [Doctoral dissertation]. Vrije Universiteit Amsterdam; 2005. [cited 2021 Mar 04].
Available from: http://hdl.handle.net/1871/9015.
Council of Science Editors:
Stas RJW. Trapping fermionic and bosonic helium atoms
. [Doctoral Dissertation]. Vrije Universiteit Amsterdam; 2005. Available from: http://hdl.handle.net/1871/9015
.