subject:(One electron oxidation)

Florida International University

1. Rayala, Ramanjaneyulu. Design and Synthesis of Novel Nucleoside Analogues: Oxidative and Reductive Approaches toward Synthesis of 2'-Fluoro Pyrimidine Nucleosides.

Degree: PhD, Chemistry, 2015, Florida International University

URL: https://digitalcommons.fiu.edu/etd/2172 ; 10.25148/etd.FIDC000129 ; FIDC000129

► Fluorinated nucleosides, especially the analogues with fluorine atom(s) in the ribose ring, have been known to exert potent biological activities. The first part of… (more)

▼ Fluorinated nucleosides, especially the analogues with fluorine atom(s) in the ribose ring, have been known to exert potent biological activities. The first part of this dissertation was aimed at developing oxidative desulfurization-fluorination and reductive desulfonylation-fluorination methodologies toward the synthesis of 2'-mono and/or 2',2'-difluoro pyrimidine nucleosides from the corresponding 2'-arylthiopyrimidine precursors. Novel oxidative desulfurization-difluorination methodology was developed for the synthesis of α,α-difluorinted esters from the corresponding α-arylthio esters, wherein the arylthio group is present on a secondary internal carbon. For the reductive desulfonylation studies, cyclic voltammetry was utilized to measure the reduction potentials at which the sulfone moiety of substrates can be cleaved. The 5-bromo pyrimidine nucleosides and 8-bromo purine nucleosides act as crucial intermediates in various synthetic transformations. The second part of the present dissertation was designed to develop a novel bromination methodology using 1,3-dibromo-5,5-dimethylhydantoin (DBH). Various protected and deprotected pyrimidine and purine nucleosides were converted to their respective C5 and C8 brominated counterparts using DBH. The effect of Lewis acids, solvents, and temperature on the efficiency of bromination was studied. Also, N-bromosuccinimide (NBS) or DBH offered a convenient access to 8-bromotoyocamycin and 8-bromosangivamycin. Third part of this research work focuses on the design and synthesis of 6-N-benzylated derivatives of 7-deazapurine nucleoside antibiotics, such as tubercidin, sangivamycin and toyocamycin. Target molecules were synthesized by two methods. First method involves treatment of 7-deazapurine substrates with benzylbromide followed by dimethylamine-promoted Dimroth rearrangement. The second method employs fluoro-diazotization followed by S_NAr displacement of the 6-fluoro group by a benzylamine. The 6-N-benzylated 7-deazapurine nucleosides showed type-specific inhibition of cancer cell proliferation at micromolar concentrations and weak inhibition of human equilibrative nucleoside transport protein (hENT1). In the fourth part of this dissertation, syntheses of C7 or C8 modified 7-deazapurine nucleosides, which might exhibit fluorescent properties, were undertaken. 8-Azidotoyocamycin was synthesized by treatment of 8-bromotoyocamycin with sodium azide. Strain promoted click chemistry of 8-azidotoyocamycin with cyclooctynes gave the corresponding 8-triazolyl derivatives. Alternatively, 7-benzotriazolyl tubercidin was synthesized by iodine catalyzed CH arylation of tubercidin with benzotriazole. Advisors/Committee Members: Stanislaw F. Wnuk, Kathleen S. Rein, David A. Becker, Anthony P. DeCaprio, Salvatore D. Lepore.

Subjects/Keywords: Fluorination; Desulfurization; Desulfonylation; Pyrimidines; Purines; 7-Deazapurines; DBH; Click Chemistry; C-H Functionalization; One Electron Oxidation; Carbohydrates; Heterocyclic Compounds; Nucleic Acids, Nucleotides, and Nucleosides

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APA (6^th Edition):

Rayala, R. (2015). Design and Synthesis of Novel Nucleoside Analogues: Oxidative and Reductive Approaches toward Synthesis of 2'-Fluoro Pyrimidine Nucleosides. (Doctoral Dissertation). Florida International University. Retrieved from https://digitalcommons.fiu.edu/etd/2172 ; 10.25148/etd.FIDC000129 ; FIDC000129

Chicago Manual of Style (16^th Edition):

Rayala, Ramanjaneyulu. “Design and Synthesis of Novel Nucleoside Analogues: Oxidative and Reductive Approaches toward Synthesis of 2'-Fluoro Pyrimidine Nucleosides.” 2015. Doctoral Dissertation, Florida International University. Accessed March 05, 2021. https://digitalcommons.fiu.edu/etd/2172 ; 10.25148/etd.FIDC000129 ; FIDC000129.

MLA Handbook (7^th Edition):

Rayala, Ramanjaneyulu. “Design and Synthesis of Novel Nucleoside Analogues: Oxidative and Reductive Approaches toward Synthesis of 2'-Fluoro Pyrimidine Nucleosides.” 2015. Web. 05 Mar 2021.

Vancouver:

Rayala R. Design and Synthesis of Novel Nucleoside Analogues: Oxidative and Reductive Approaches toward Synthesis of 2'-Fluoro Pyrimidine Nucleosides. [Internet] [Doctoral dissertation]. Florida International University; 2015. [cited 2021 Mar 05]. Available from: https://digitalcommons.fiu.edu/etd/2172 ; 10.25148/etd.FIDC000129 ; FIDC000129.

Council of Science Editors:

Rayala R. Design and Synthesis of Novel Nucleoside Analogues: Oxidative and Reductive Approaches toward Synthesis of 2'-Fluoro Pyrimidine Nucleosides. [Doctoral Dissertation]. Florida International University; 2015. Available from: https://digitalcommons.fiu.edu/etd/2172 ; 10.25148/etd.FIDC000129 ; FIDC000129

2. Saracini, Claudio. CARBON MONOXIDE AND DIOXYGEN PHOTO-RELEASE, BINDING KINETICS, AND THERMODYNAMICS IN 1:1 MONONUCLEAR AND 2:1 DINUCLEAR COPPER/DIOXYGEN COMPLEXES.

Degree: 2014, Johns Hopkins University

URL: http://jhir.library.jhu.edu/handle/1774.2/37054

► Enzymes where the active site contains one or more copper ions catalyze a wide range of organic substrate transformations in Nature. The structures and function… (more)

▼ Enzymes where the active site contains one or more copper ions catalyze a wide range of organic substrate transformations in Nature. The structures and function of such active sites have been finely tuned by evolution to reach the point where dioxygen binding, activation, and utilization for oxidative chemistry has become finely modulated. As is overviewed in Chapter 1, it is useful to categorize the enzymes supported by two copper centers in their active sites as 'uncoupled' (i.e. in peptidylglycine -hydroxylating monooxygenase (PHM) and in dopamine -monooxygenase (DM)) or 'coupled' (i.e. in tyrosinase (Tyr) and in catechol oxidase (Co)) on the basis of the spatial proximity of the two metals in the three-dimensional matrix of the protein. This proximity has profound effects on the chemistry displayed by these two classes of enzymes. Importantly, dioxygen binding to the copper centers is the first step of the catalytic cycle in all of these systems. However, both mononuclear 1:1 and dinuclear 2:1 copper/O2 adducts forming in the enzymes have been shown to be unstable and their detection and their study has been difficult. As it is also discussed in Chapter 1, low temperature spectroscopic techniques together with synthetic model chemistry have come into play and greatly improved our understanding of the mechanistic details involved in such kinds of reactivity. In this work, laser flash-photolysis techniques in combination with copper-synthetic model chemistry have been employed to help the elucidation of fundamental physical and chemical properties of copper/O2 coordination and dynamics. One of the methods that has been successfully employed to study labile copper/dioxygen adducts is laser flash-photolysis of synthetic (L)copper(I)-CO compounds (L =ligand) in the presence of O2 in organic solvents. In Chapter 2, a flash-photolysis study of tridentate N-donor ligand-copper(I)-CO complexes is presented using such techniques. The implications of tricoordination vs. tetracoordination of copper ion on the dynamics of CO and O2 binding to the metal are discussed for these metal complexes. Tricoordinate environments are more similar in their coordination sphere with those present in the enzymes, as compared to their tetracoordinated synthetic counterparts. In Chapter 3, a new method to study copper/dioxygen binding for mononuclear copper complexes is presented. The previously employed carbon monoxide utilization to start from stable (L)copper(I)-CO complexes is bypassed, in this work, by affording direct O2 photo-release from relatively stable mononuclear copper(II)-superoxide complexes. Interestingly, a different quantum yield for O2 release was found depending on the excitation wavelength used and in collaborative efforts, this effect has been investigated by means of Time-Dependent Density Functional Theory (TD-DFT) studies. This work was further extended and presented in Chapter 4, where the same technique was employed for dinuclear 2:1 Cu/O2 synthetic adducts with a peroxo fragment bound in a side-on mode to the… Advisors/Committee Members: Karlin, Kenneth D (advisor).

Subjects/Keywords: Oxygen activation; coupled copper enzymes; uncoupled copper enzymes; mononuclear and dinuclear copper?O2 adducts; copper synthetic model chemistry; laser flash-photolysis; physical properties; transient absorption spectroscopy; carbon monoxide; dioxygen; tricoordinate; tetracoordinate; flash-and-trap method; copper(II)-superoxide; dicopper(II) peroxo; quantum yield; excitation wavelength; TD-DFT; end-on; side-on; irradiation; visible light; one-photon two-electron; oxidation; hydrogen atom abstraction; reversible; thermodynamics; kinetics; kinetic relaxation model; pseudo-first-order; second-order; rate constant; binding dynamics; tyrosinase; hemocyanin; catechol oxidase; PHM; DBM; irradiation; laser.

…119 viii Chapter 4: One-Photon Two-Electron Oxidation of Peroxide to O2 from Dicopper… …x27;. 145 Scheme 1. One-photon two-electron oxidation of peroxide to dioxygen. 136… …oxidation and the other one functions as electron source/carrier. In enzymes such as tyrosinase… …Photon Two-Electron Oxidation of Peroxide to O2 from Dicopper(II) Compounds Page… …dioxygen. Upon dioxygen binding, each copper ion is oxidized by one electron and dioxygen is…

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APA (6^th Edition):

Saracini, C. (2014). CARBON MONOXIDE AND DIOXYGEN PHOTO-RELEASE, BINDING KINETICS, AND THERMODYNAMICS IN 1:1 MONONUCLEAR AND 2:1 DINUCLEAR COPPER/DIOXYGEN COMPLEXES. (Thesis). Johns Hopkins University. Retrieved from http://jhir.library.jhu.edu/handle/1774.2/37054

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Saracini, Claudio. “CARBON MONOXIDE AND DIOXYGEN PHOTO-RELEASE, BINDING KINETICS, AND THERMODYNAMICS IN 1:1 MONONUCLEAR AND 2:1 DINUCLEAR COPPER/DIOXYGEN COMPLEXES.” 2014. Thesis, Johns Hopkins University. Accessed March 05, 2021. http://jhir.library.jhu.edu/handle/1774.2/37054.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Saracini, Claudio. “CARBON MONOXIDE AND DIOXYGEN PHOTO-RELEASE, BINDING KINETICS, AND THERMODYNAMICS IN 1:1 MONONUCLEAR AND 2:1 DINUCLEAR COPPER/DIOXYGEN COMPLEXES.” 2014. Web. 05 Mar 2021.

Vancouver:

Saracini C. CARBON MONOXIDE AND DIOXYGEN PHOTO-RELEASE, BINDING KINETICS, AND THERMODYNAMICS IN 1:1 MONONUCLEAR AND 2:1 DINUCLEAR COPPER/DIOXYGEN COMPLEXES. [Internet] [Thesis]. Johns Hopkins University; 2014. [cited 2021 Mar 05]. Available from: http://jhir.library.jhu.edu/handle/1774.2/37054.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Saracini C. CARBON MONOXIDE AND DIOXYGEN PHOTO-RELEASE, BINDING KINETICS, AND THERMODYNAMICS IN 1:1 MONONUCLEAR AND 2:1 DINUCLEAR COPPER/DIOXYGEN COMPLEXES. [Thesis]. Johns Hopkins University; 2014. Available from: http://jhir.library.jhu.edu/handle/1774.2/37054

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

3. Remy, Matthew Sean. Group 10 Methyl Transfer Reactions toward Catalyst Development for Oxidative Oligomerization of Methane.

Degree: PhD, Chemistry, 2011, University of Michigan

URL: http://hdl.handle.net/2027.42/86311

► Abstract Group 10 Methyl Transfer Reactions toward Catalyst Development for Oxidative Oligomerization of Methane by Matthew Sean Remy Chair: Melanie S. Sanford One of the… (more)

▼ Abstract Group 10 Methyl Transfer Reactions toward Catalyst Development for Oxidative Oligomerization of Methane by Matthew Sean Remy Chair: Melanie S. Sanford One of the challenges of developing a homogeneous catalyst for oxidative oligomerization of methane (OOM) is promoting a C–C coupling reaction from the product of alkane C–H activation. Heterolytic C–H activation of methane almost exclusively generates a monoalkyl-metal species. In order to make a new C–C bond, it is proposed that a polymethyl intermediate must be generated. Our studies showed that aryl disproportionation is far more favorable than methyl disproportionation. Careful tuning of ancillary ligands at monomethyl-palladium(II) complexes using density functional theory (DFT) calculations facilitated optimization of thermodynamics for methyl disproportionation. This allowed the first observed disproportionation reaction to form a dimethyl-palladium(II) complex. Heating dimethyl complex (tBu-bpy)PdII(CH3)2 (tBu-bpy = 4,4-ditertbutyl-2,2-bipyridine) to 100 °C produced a mixture of methane and ethane over 24 h. One-electron oxidants and 1,4-benzoquinone were found to be effective promoters of ethane formation from (tBu-bpy)PdII(CH3)2 at 25 °C. Mechanistic study of one-electron oxidation uncovered an oxidatively-induced methyl transfer reaction which produced ethane from [(tBu-bpy)PdIV(CH3)3(solvent)]+. Subsequently, one-electron oxidation of complexes of the general formula (tBu-bpy)PdII(CH3)X was developed as an effective method for generation of ethane from monomethyl-palladium(II) complexes. Platinum complexes, (N–N)PtII(CH3)2, similarly undergo one-electron to produce [(N–N)PtIV(CH3)3(solvent)]+. However, these platinum(IV) products are generally stable to reductive elimination of ethane. When the N–N ligand is designed to have steric interactions with axial ligands of platinum(IV), ethane reductive elimination becomes favorable, occurring cleanly over 8.5 hours in acetone and over 1 h in dichloromethane. This document describes experimental evidence for the generation of polymethyl palladium and platinum complexes from model palladium(II) and platinum(II) products of C–H activation subsequent ethane elimination from the polymethyl complexes. In an unrelated project, N-insertion into palladium-carbon bond was observed when palladium(II) complexes of bidentate C–N ligands were reacted with an iminoiodinane oxidant. The reaction was proposed to occur through an imido-palladium(IV) intermediate. Advisors/Committee Members: Sanford, Melaine S. (committee member), Banaszak Holl, Mark M. (committee member), Hollenberg, Paul F. (committee member), Lehnert, Nicolai (committee member).

Subjects/Keywords: One-electron Oxidation of Palladium and Platinum; Methyl Group Transfer; Gas to Liquids; Chemistry; Science

…84 One-Electron Oxidation of Monomethyl Palladium(II) Complexes… …120 Stoichiometric Studies of Disproportionation, One-Electron Oxidation and Reductive… …3.40 One-Electron Oxidation of 1 to Produce Ethane… …75 Scheme 3.41 Formation of a PdIV-Trimethyl Intermediate Upon One-Electron Oxidation… …76 Scheme 3.44 One-Electron Oxidation of Dimethyl-platinum Diimine Complexes.38 ..... 76…

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APA (6^th Edition):

Remy, M. S. (2011). Group 10 Methyl Transfer Reactions toward Catalyst Development for Oxidative Oligomerization of Methane. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/86311

Chicago Manual of Style (16^th Edition):

Remy, Matthew Sean. “Group 10 Methyl Transfer Reactions toward Catalyst Development for Oxidative Oligomerization of Methane.” 2011. Doctoral Dissertation, University of Michigan. Accessed March 05, 2021. http://hdl.handle.net/2027.42/86311.

MLA Handbook (7^th Edition):

Remy, Matthew Sean. “Group 10 Methyl Transfer Reactions toward Catalyst Development for Oxidative Oligomerization of Methane.” 2011. Web. 05 Mar 2021.

Vancouver:

Remy MS. Group 10 Methyl Transfer Reactions toward Catalyst Development for Oxidative Oligomerization of Methane. [Internet] [Doctoral dissertation]. University of Michigan; 2011. [cited 2021 Mar 05]. Available from: http://hdl.handle.net/2027.42/86311.

Council of Science Editors:

Remy MS. Group 10 Methyl Transfer Reactions toward Catalyst Development for Oxidative Oligomerization of Methane. [Doctoral Dissertation]. University of Michigan; 2011. Available from: http://hdl.handle.net/2027.42/86311

Osaka University

4. Choi, Jun Rye; 崔, 俊禮. Studies on the Photoinduced Charge-Transfer Processes on Metal-Organic Framework Nanoparticles and Their Composites : 多孔性金属-有機骨格ナノ粒子およびその複合材料における光誘起電荷移動過程に関する研究; タコウセイ　キンゾク　ユウキ　コッカク　ナノ　リュウシ　オヨビ　ソノ　フクゴウ　ザイリョウ　ニ　オケル　ヒカリ　ユウキ　デンカ　イドウ　カテイ　ニ　カンスル　ケンキュウ.

Degree: 博士（工学）, 2010, Osaka University

URL: http://hdl.handle.net/11094/27634

博士（工学）

2010-09-22

大阪大学

14401甲第14545号

24187

Subjects/Keywords: Metal-Organic Frameworks; Europium-based MOF; One-Electron Oxidation

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APA (6^th Edition):

Choi, Jun Rye; 崔, �. �. (2010). Studies on the Photoinduced Charge-Transfer Processes on Metal-Organic Framework Nanoparticles and Their Composites : 多孔性金属-有機骨格ナノ粒子およびその複合材料における光誘起電荷移動過程に関する研究; タコウセイ　キンゾク　ユウキ　コッカク　ナノ　リュウシ　オヨビ　ソノ　フクゴウ　ザイリョウ　ニ　オケル　ヒカリ　ユウキ　デンカ　イドウ　カテイ　ニ　カンスル　ケンキュウ. (Thesis). Osaka University. Retrieved from http://hdl.handle.net/11094/27634

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Choi, Jun Rye; 崔, 俊禮. “Studies on the Photoinduced Charge-Transfer Processes on Metal-Organic Framework Nanoparticles and Their Composites : 多孔性金属-有機骨格ナノ粒子およびその複合材料における光誘起電荷移動過程に関する研究; タコウセイ　キンゾク　ユウキ　コッカク　ナノ　リュウシ　オヨビ　ソノ　フクゴウ　ザイリョウ　ニ　オケル　ヒカリ　ユウキ　デンカ　イドウ　カテイ　ニ　カンスル　ケンキュウ.” 2010. Thesis, Osaka University. Accessed March 05, 2021. http://hdl.handle.net/11094/27634.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Choi, Jun Rye; 崔, 俊禮. “Studies on the Photoinduced Charge-Transfer Processes on Metal-Organic Framework Nanoparticles and Their Composites : 多孔性金属-有機骨格ナノ粒子およびその複合材料における光誘起電荷移動過程に関する研究; タコウセイ　キンゾク　ユウキ　コッカク　ナノ　リュウシ　オヨビ　ソノ　フクゴウ　ザイリョウ　ニ　オケル　ヒカリ　ユウキ　デンカ　イドウ　カテイ　ニ　カンスル　ケンキュウ.” 2010. Web. 05 Mar 2021.

Vancouver:

Choi, Jun Rye; 崔 ��. Studies on the Photoinduced Charge-Transfer Processes on Metal-Organic Framework Nanoparticles and Their Composites : 多孔性金属-有機骨格ナノ粒子およびその複合材料における光誘起電荷移動過程に関する研究; タコウセイ　キンゾク　ユウキ　コッカク　ナノ　リュウシ　オヨビ　ソノ　フクゴウ　ザイリョウ　ニ　オケル　ヒカリ　ユウキ　デンカ　イドウ　カテイ　ニ　カンスル　ケンキュウ. [Internet] [Thesis]. Osaka University; 2010. [cited 2021 Mar 05]. Available from: http://hdl.handle.net/11094/27634.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Choi, Jun Rye; 崔 ��. Studies on the Photoinduced Charge-Transfer Processes on Metal-Organic Framework Nanoparticles and Their Composites : 多孔性金属-有機骨格ナノ粒子およびその複合材料における光誘起電荷移動過程に関する研究; タコウセイ　キンゾク　ユウキ　コッカク　ナノ　リュウシ　オヨビ　ソノ　フクゴウ　ザイリョウ　ニ　オケル　ヒカリ　ユウキ　デンカ　イドウ　カテイ　ニ　カンスル　ケンキュウ. [Thesis]. Osaka University; 2010. Available from: http://hdl.handle.net/11094/27634

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

5. Καλούδης, Παναγιώτης. Μελέτη προϊόντων οξειδωτικής καταστροφής του DNA.

Degree: 2009, National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ)

URL: http://hdl.handle.net/10442/hedi/19422

► The genetic degeneration and instability of the human genome has been linked intimately with all aspects of maintenance of DNA integrity, which is a macromolecule… (more)

▼ The genetic degeneration and instability of the human genome has been linked intimately with all aspects of maintenance of DNA integrity, which is a macromolecule constantly targeted by environmental and endogenous genotoxic agents. DNA appears to be a critical cellular target for the biological effects of oxidation processes mediated by various physical and chemical agents such as ionizing radiation, solar light, photosensitizers, and several enviromental carcinogens. The endogenous production of reactive oxygen species represents another source of oxidative stress for the cells, while the mechanisms for the production of oxidative DNA damage products have been thoroughly studied due to their paramount significance in a number of biological processes. The target of the present thesis was the synthesis and the radiolytic study of modified nucleosidic derivatives in an effort to determine the mechanisms involved in DNA damage. The main tools utilized in the aforementioned studies were the observation of the absorption spectra of the active intermediates through pulse radiolysis and their interpretation through theoretical calculations and characterization of the final stable products through γ-radiolysis experiments. The independent and site-specific generation of nucleosidic radicals on the sugar or the base moiety is a particularly useful tool for studying the radical mechanisms involved. We performed the synthesis of the photolabile derivatives 4.2 and 3.22, which under photolysis generate selectively the neutral radical of the one electron oxidized guanine without the simultaneous formation of the superoxide radical anion, and the C1΄ sugar radical of 2΄-deoxyadenosine, respectively. The opening of the cyclobutane ring of the cis-syn thymine dimer 2.3 was studied and a new mechanism was proposed for this process, which contradicts the widely accepted view of a chain radical mechanism. Moreover, the chemistry of the C5΄ radical of 2΄-deoxyadenosine (3.11), 2΄-deoxyinosine (3.14) and 2΄-deoxyguanosine (3.16) was also studied under various conditions, while the radiolytic study of 8-oxo-2΄-deoxyguanosine (4.1) and other 8-substituted purine nucleosides in the effort of elucidating the mechanisms involved were performed as well. Tautomerization of nucleosidic radicals was discovered recently in the one electron oxidized guanosine. With the purpose of finding new nucleosidic derivatives that exhibit radical tautomerization, as well as the specific characteristics that enable this process, 8-bromo-2-aminoadenosine (5.14), 8-bromoxanthosine (5.15) and 8-bromoisoguanosine (5.16) were synthesized and studied by radiolytic means. Indeed, it was found that reaction of 5.14 with hydrated electrons affords two tautomers, while the mechanism for the one electron reduction of 5.15 and 5.16 was determined. Finally, the one electron reduction of guanosine was reevaluated and the existence of two tautomeric forms of the one electron reduced guanine was discovered, while radiolytic studies of the reaction between…

Subjects/Keywords: Παλμική ραδιόλυση; γ - ραδιόλυση; Ριζική ταυτομέρεια νουκλεοζιτών; Ηλεκτρόνιο, Οξείδωση ενός; Ηλεκτρόνιο, Αναγωγή ενός; Φωτόλυση; Θεωρητικοί υπολογισμοί; Ocidative DNA damage; Pulse radiolysis; γ - radiolysis; Nucleosidic radical tautomerization; One electron oxidation; One electron rediction; Photolysis; Theoretical calculations

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Καλούδης, . �. (2009). Μελέτη προϊόντων οξειδωτικής καταστροφής του DNA. (Thesis). National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Retrieved from http://hdl.handle.net/10442/hedi/19422

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Καλούδης, Παναγιώτης. “Μελέτη προϊόντων οξειδωτικής καταστροφής του DNA.” 2009. Thesis, National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Accessed March 05, 2021. http://hdl.handle.net/10442/hedi/19422.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Καλούδης, Παναγιώτης. “Μελέτη προϊόντων οξειδωτικής καταστροφής του DNA.” 2009. Web. 05 Mar 2021.

Vancouver:

Καλούδης �. Μελέτη προϊόντων οξειδωτικής καταστροφής του DNA. [Internet] [Thesis]. National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ); 2009. [cited 2021 Mar 05]. Available from: http://hdl.handle.net/10442/hedi/19422.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Καλούδης �. Μελέτη προϊόντων οξειδωτικής καταστροφής του DNA. [Thesis]. National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ); 2009. Available from: http://hdl.handle.net/10442/hedi/19422

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Georgia Tech

6. Roberts, Lezah Wilette. Effect of Netropsin on One-electron Oxidation of DNA.

Degree: PhD, Chemistry and Biochemistry, 2005, Georgia Tech

URL: http://hdl.handle.net/1853/7228

► One electron oxidation of DNA has been studied extensively over the years. When a charge is injected into a DNA duplex, it migrates through the… (more)

Subjects/Keywords: Photosensitizer; Charge transfer; Netropsin; TQ; DNA; Electron transfer; One-electron oxidation; Photosensitization, Biological; Charge transfer in biology; DNA Analysis; Oxidation, Physiological

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APA (6^th Edition):

Roberts, L. W. (2005). Effect of Netropsin on One-electron Oxidation of DNA. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/7228

Chicago Manual of Style (16^th Edition):

Roberts, Lezah Wilette. “Effect of Netropsin on One-electron Oxidation of DNA.” 2005. Doctoral Dissertation, Georgia Tech. Accessed March 05, 2021. http://hdl.handle.net/1853/7228.

MLA Handbook (7^th Edition):

Roberts, Lezah Wilette. “Effect of Netropsin on One-electron Oxidation of DNA.” 2005. Web. 05 Mar 2021.

Vancouver:

Roberts LW. Effect of Netropsin on One-electron Oxidation of DNA. [Internet] [Doctoral dissertation]. Georgia Tech; 2005. [cited 2021 Mar 05]. Available from: http://hdl.handle.net/1853/7228.

Council of Science Editors:

Roberts LW. Effect of Netropsin on One-electron Oxidation of DNA. [Doctoral Dissertation]. Georgia Tech; 2005. Available from: http://hdl.handle.net/1853/7228

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