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Addis Ababa University
1.
Nigatu, Endalafer.
susceptibility patterns in surgical wards and surgical Intensive care unit (SICU) of Tikur Anbessa University Hospital Addis Ababa, Ethiopia.
Degree: 2012, Addis Ababa University
URL: http://etd.aau.edu.et/dspace/handle/123456789/2934 
► Background: Nosocomial infections are defined as infections which are not present or not incubating when the patient is hospitalized and are acquired during hospital stay.…
(more)
▼ Background:
Nosocomial infections are defined as infections which are not present or not
incubating when the patient is hospitalized and are acquired during hospital stay. Sign and
symptoms of the
infection may be evident during hospitalization or after discharge related to
the length of the incubation period. It is usually defined as an
infection that is identified at
least 48-72 hours following admission to health institution. Infections acquired in hospital
are likely to complicate illness, cause anxiety and discomfort, and can lead to death.
Nosocomial infection is a global problem with multi facet out comes. The problem is well
pronounced in developing countries. Epidemiological and etiological characteristics of
nosocomial infections show variations among countries and even among different hospitals
in the same country. Many of these infections are associated with micro-organisms that are
resistant to multiple antibiotics and can easily spread on the hands of personnel. The most
frequent types of
nosocomial infections are urinary-tract
infection,
surgical-wound
infection,
pneumonia, and bloodstream
infection. At present, the emergence of resistance to
antimicrobial agents is a global public health problem, particularly in pathogens causing
nosocomial infections. Antimicrobial resistance results in increased morbidity, mortality and
health-care costs.
Objective: To determine the prevalence, etiological agents and drug susceptibility pattern of
nosocomial infections at Tikur Anbessa University Hospital.
Methods: A cross-sectional study was conducted from June 2007 to April 2008 at Tikur
Anbessa University Hospital, Addis Ababa, Ethiopia. During the study, all adult patients
admitted to
surgical wards and SICU with suspected of
nosocomial infection were included.
Among 854 patients admitted to
surgical wards and SICU, 215 patients selected based on
their clinical ground, after a careful clinical examination. Clinical samples were collected
from the study
subject and analyzed accordingly.
Results: Eight hundred fifty four patients admitted to
surgical ward and SICU between June
2007 and April 2008 to Tikur Anbessa University Hospital in Addis Ababa were studied for
prevalence of
nosocomial infections. A total of 215(25.2%) patients, were selected based on
their clinical grounds from
surgical wards (n=161) and SICU (n=54). The mean hospital stay
from the date of admission until sample collection was 16.72 days with a range of 3 to 66
days. Of the 215 patients, 130(60.5%) were males and 85 (39.5%) were females. A total of
nine percent (77/854) patients were confirmed to have
nosocomial infections. Of the 77
patients, 51(66.2%) were males and 26(33.8%) females. The distribution of
nosocomial
infections among positive cases was
surgical site infection 38(49.4%), urinary tract
infections 23(29.8%) and blood stream
infection 16(20.8%). The Gram-positive and
negative bacteria accounted for 23/84(23.4%) and 61/84(72.6%) respectively. A total of 84
bacterial pathogens (strains) were isolated, E. coli accounted for 19.0% of…
Advisors/Committee Members: Dr. Solomon Gebre-Selassie (advisor).
Subjects/Keywords: Nosocomial infection, Surgical Site Infection,;
Intensive Care Unit;
Urinary Tract Infection;
Blood Stream Infection
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APA (6th Edition):
Nigatu, E. (2012). susceptibility patterns in surgical wards and surgical Intensive care unit (SICU) of Tikur Anbessa University Hospital Addis Ababa, Ethiopia.
(Thesis). Addis Ababa University. Retrieved from http://etd.aau.edu.et/dspace/handle/123456789/2934
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Nigatu, Endalafer. “susceptibility patterns in surgical wards and surgical Intensive care unit (SICU) of Tikur Anbessa University Hospital Addis Ababa, Ethiopia.
” 2012. Thesis, Addis Ababa University. Accessed April 18, 2021.
http://etd.aau.edu.et/dspace/handle/123456789/2934.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Nigatu, Endalafer. “susceptibility patterns in surgical wards and surgical Intensive care unit (SICU) of Tikur Anbessa University Hospital Addis Ababa, Ethiopia.
” 2012. Web. 18 Apr 2021.
Vancouver:
Nigatu E. susceptibility patterns in surgical wards and surgical Intensive care unit (SICU) of Tikur Anbessa University Hospital Addis Ababa, Ethiopia.
[Internet] [Thesis]. Addis Ababa University; 2012. [cited 2021 Apr 18].
Available from: http://etd.aau.edu.et/dspace/handle/123456789/2934.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Nigatu E. susceptibility patterns in surgical wards and surgical Intensive care unit (SICU) of Tikur Anbessa University Hospital Addis Ababa, Ethiopia.
[Thesis]. Addis Ababa University; 2012. Available from: http://etd.aau.edu.et/dspace/handle/123456789/2934
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Dalhousie University
2.
Stefanuto, Peter.
EFFECTIVENESS OF HOSPITAL CENTRAL STERILIZATION PROCESSING
VS. CLINIC-BASED STERILIZATION PROTOCOLS: A NON-INFERIORITY
TRIAL.
Degree: MS, Oral & Maxillofacial Surgery, 2014, Dalhousie University
URL: http://hdl.handle.net/10222/54542
► Purpose: .The purpose of the study was to determine if clinic-based sterilization is non-inferior to hospital-based central sterilization. Methods: This study was a blinded and…
(more)
▼ Purpose: .The purpose of the study was to determine if
clinic-based sterilization is non-inferior to hospital-based
central sterilization. Methods: This study was a blinded and
standardized, direct comparison of commonly used sterilization
methods. Clinic-based sterilization was compared with
hospital-based central sterilization for usage with non-complex
surgical instruments. Instruments (n=1264) were randomly assigned
to 1 of 5 groups as either test groups (Groups A, B, C) or negative
control groups (Groups D, E). Groups A, B and C were artificially
inoculated using vital strain of E. faecalis and S. aureus, Groups
D and E were non-inoculated negative controls. Test Groups B and C
(n=593 and n=584) were sterilized using either a clinic based
sterilization protocol or hospital-based central sterilization
protocol, whereas Group A was used to determine the viability of
methods used. All groups were then incubated at 37 degrees Celsius
in a validated culture medium (Tryptic-soy broth) for 72 hours and
checked for bacterial growth (turbidity) by a single blinded
observer. Results: Group B (clinic-based sterilization) the rate of
successful sterilization was 99.8314% (592/593) and for Group C
(hospital-based sterilization) the rate was 100% (584/584). Groups
A, D, and E were used to determine the validity of the results.
Statistical analyses of all variables failed to identify
significant differences between test Groups B and C at a 95%
confidence interval. Conclusion: From this study we can conclude
that for non-complex
surgical instruments, centrally-based
sterilization protocols and clinic based sterilization protocols
are equivalent in sterilization. Thus, other factors should be
considered when determining which sterilization method is
appropriate for each specific department within a hospital
setting.
Advisors/Committee Members: Dr. Walter Schlech (external-examiner), Dr. Archibald Morrison (graduate-coordinator), Dr. Curtis Gregoire (thesis-reader), Dr. Jean Charles Doucet (thesis-reader), Dr. Archibald Morrison (thesis-supervisor), Not Applicable (ethics-approval), Not Applicable (manuscripts), Not Applicable (copyright-release).
Subjects/Keywords: infection control; surgical site wound infection; sterilization
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APA (6th Edition):
Stefanuto, P. (2014). EFFECTIVENESS OF HOSPITAL CENTRAL STERILIZATION PROCESSING
VS. CLINIC-BASED STERILIZATION PROTOCOLS: A NON-INFERIORITY
TRIAL. (Masters Thesis). Dalhousie University. Retrieved from http://hdl.handle.net/10222/54542
Chicago Manual of Style (16th Edition):
Stefanuto, Peter. “EFFECTIVENESS OF HOSPITAL CENTRAL STERILIZATION PROCESSING
VS. CLINIC-BASED STERILIZATION PROTOCOLS: A NON-INFERIORITY
TRIAL.” 2014. Masters Thesis, Dalhousie University. Accessed April 18, 2021.
http://hdl.handle.net/10222/54542.
MLA Handbook (7th Edition):
Stefanuto, Peter. “EFFECTIVENESS OF HOSPITAL CENTRAL STERILIZATION PROCESSING
VS. CLINIC-BASED STERILIZATION PROTOCOLS: A NON-INFERIORITY
TRIAL.” 2014. Web. 18 Apr 2021.
Vancouver:
Stefanuto P. EFFECTIVENESS OF HOSPITAL CENTRAL STERILIZATION PROCESSING
VS. CLINIC-BASED STERILIZATION PROTOCOLS: A NON-INFERIORITY
TRIAL. [Internet] [Masters thesis]. Dalhousie University; 2014. [cited 2021 Apr 18].
Available from: http://hdl.handle.net/10222/54542.
Council of Science Editors:
Stefanuto P. EFFECTIVENESS OF HOSPITAL CENTRAL STERILIZATION PROCESSING
VS. CLINIC-BASED STERILIZATION PROTOCOLS: A NON-INFERIORITY
TRIAL. [Masters Thesis]. Dalhousie University; 2014. Available from: http://hdl.handle.net/10222/54542
Addis Ababa University
3.
ASCHALEW, GELAW.
ISOLATION OF BACTERIAL PATHOGENS FROM PATIENTS WITH POSTOPERATIVE SURGICAL SITE INFECTIONS AND POSSIBLE SOURCES OF INFECTIONS AT UNIVERSITY OF GONDAR HOSPITAL, NORTHWEST ETHIOPIA
.
Degree: 2012, Addis Ababa University
URL: http://etd.aau.edu.et/dspace/handle/123456789/2899
► Background: Hospital environment is a potential reservoir of bacterial pathogens since it houses both patients with diverse pathogenic microorganisms and a large number of susceptible…
(more)
▼ Background: Hospital environment is a potential reservoir of bacterial pathogens since it houses
both patients with diverse pathogenic microorganisms and a large number of susceptible
individuals. The increased frequency of bacterial pathogens in hospital environment is associated
with a background rise in various types of
nosocomial infections.
Surgical site infection is one of
the most frequent types of
nosocomial infections in developing countries. The
infection follows
interference with the skin barrier, and is associated with the intensity of bacterial contamination
of the wound at surgery or later in wards during wound care. Bacterial pathogens isolated from
hospital environments are also known to develop resistance to multiple antimicrobial agents. The
emergence of multi-drug resistant organisms in hospital results in difficulty to treat
nosocomial
infections.
Objective: The aim of this study was to isolate and identify bacterial pathogens from hospital
environments & patients with postoperative
surgical site infections and assess the antimicrobial
susceptibility patterns of the isolates.
Methods: A cross sectional study was conducted at the University of Gondar Teaching Hospital
from November 2010 - February 2011. In order to address the specified objectives, 220
specimens of pus, nasal, hand and surfaces swabs were collected using sterile cotton tipped
swabs moistened with normal saline. Colony characteristics and Gram’s technique were used to
differentiate the organisms. Biochemical tests were done to confirm the species of the organisms.
Antimicrobial sensitivity tests were done on the isolates using the disk diffusion method.
Result: A total of 268 bacterial pathogens were recovered from all specimens processed in the
study. Most of the isolates, 142(52.9%) were from the environments. The rest, 77(28.8%) and
49(18.3%) were recovered from the health professionals and patients, respectively. The
organisms associated with postoperative
surgical site infections were S. aureus 11(22.4%)
followed by Klebsiella species 10(20.4%) and Proteus species 9(18.4%), Escherichia coli
6(12.2%), Enterobacter species and coagulase negative staphylococci each 4(8.2%),
Pseudomonas aeruginosa 3(6.1%) and Citrobacter species 2(4.1%). Gram negative rods isolated
from different sample sources were deemed highly resistant to ampicillin 72(90%),
cotrimoxazole, 68 (85%), doxycycline, 66 (82.5%), tetracycline, 63(78.8%), chloramphenicol, 48
(60%), nalidixic acid, 46 (57.5%) and gentamicin, 38 (47.5%). S. aureus demonstrated high level
VII
of resistance to nalidixic acid and tetracycline while, ceftriaxone and ciprofloxacin were found to
be relatively effective to all the isolates.
Conclusion: The predominant causes of postoperative
surgical site infections were S. aureus,
Klebsiella and proteus species. Medical equipment, environmental surfaces, air and hands of
health personnel were found to be contaminated with various types of bacterial pathogens of
nosocomial importance. It is imperative that all professionals should take an…
Advisors/Committee Members: SOLOMON GEBRE-SELASSIE (MD, M.SC): (advisor).
Subjects/Keywords: postoperative surgical site infection;
Hospital environments
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APA ·
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APA (6th Edition):
ASCHALEW, G. (2012). ISOLATION OF BACTERIAL PATHOGENS FROM PATIENTS WITH POSTOPERATIVE SURGICAL SITE INFECTIONS AND POSSIBLE SOURCES OF INFECTIONS AT UNIVERSITY OF GONDAR HOSPITAL, NORTHWEST ETHIOPIA
. (Thesis). Addis Ababa University. Retrieved from http://etd.aau.edu.et/dspace/handle/123456789/2899
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
ASCHALEW, GELAW. “ISOLATION OF BACTERIAL PATHOGENS FROM PATIENTS WITH POSTOPERATIVE SURGICAL SITE INFECTIONS AND POSSIBLE SOURCES OF INFECTIONS AT UNIVERSITY OF GONDAR HOSPITAL, NORTHWEST ETHIOPIA
.” 2012. Thesis, Addis Ababa University. Accessed April 18, 2021.
http://etd.aau.edu.et/dspace/handle/123456789/2899.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
ASCHALEW, GELAW. “ISOLATION OF BACTERIAL PATHOGENS FROM PATIENTS WITH POSTOPERATIVE SURGICAL SITE INFECTIONS AND POSSIBLE SOURCES OF INFECTIONS AT UNIVERSITY OF GONDAR HOSPITAL, NORTHWEST ETHIOPIA
.” 2012. Web. 18 Apr 2021.
Vancouver:
ASCHALEW G. ISOLATION OF BACTERIAL PATHOGENS FROM PATIENTS WITH POSTOPERATIVE SURGICAL SITE INFECTIONS AND POSSIBLE SOURCES OF INFECTIONS AT UNIVERSITY OF GONDAR HOSPITAL, NORTHWEST ETHIOPIA
. [Internet] [Thesis]. Addis Ababa University; 2012. [cited 2021 Apr 18].
Available from: http://etd.aau.edu.et/dspace/handle/123456789/2899.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
ASCHALEW G. ISOLATION OF BACTERIAL PATHOGENS FROM PATIENTS WITH POSTOPERATIVE SURGICAL SITE INFECTIONS AND POSSIBLE SOURCES OF INFECTIONS AT UNIVERSITY OF GONDAR HOSPITAL, NORTHWEST ETHIOPIA
. [Thesis]. Addis Ababa University; 2012. Available from: http://etd.aau.edu.et/dspace/handle/123456789/2899
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Universidade de Lisboa
4.
Miranda, Luís Manuel Rabaça Pires Coutinho de, 1959-.
Determinação da taxa de incidência da infecção do local cirúrgico no serviço de Cirurgia Cardiotorácica do Hospital de Santa Marta em 2008.
Degree: 2010, Universidade de Lisboa
URL: http://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/1919
► INTRODUCAO A Infeccao do Local Cirurgico (ILC) implica uma proliferacao bacteriana e subsequente reaccao inflamatoria nas zonas associadas a cirurgia, a maior parte das vezes…
(more)
▼ INTRODUCAO
A Infeccao do Local Cirurgico (ILC) implica uma proliferacao bacteriana e
subsequente reaccao inflamatoria nas zonas associadas a cirurgia, a maior parte das
vezes na propria incisao cirurgica. Nas suas expressoes mais graves pode condicionar
uma reaccao inflamatoria sistemica com disfuncao ou falencia multiorganica, associada
a um aumento de mortalidade e morbilidade. Este tipo de noxa e relativamente
frequente na pratica cirurgica hospitalar, seja num servico de Cirurgia Geral, seja num de
uma especialidade cirurgica como a da Cirurgia Cardiotoracica (CCT). Apesar disso, uma
quantificacao e caracterizacao da ILC sao bastante dificeis de obter na pratica diaria dos
servicos cirurgicos. A construcao de um registo semi-automatico alimentado por outras
bases de dados direccionado para a caracterizacao deste tipo de infeccoes pode
constituir uma alternativa ao gold-standard, representado por estudos de coorte
especificos, prospectivos e com pessoal dedicado atribuido. A sua elaboracao podera
comecar numa primeira fase pela construcao de um sistema menos complexo, cujo
objectivo principal seja somente a determinacao da taxa de incidencia da ILC no servico,
mas que sirva simultaneamente para implementar toda a metodologia do futuro registo.
OBJECTIVO PRINCIPAL
No contexto do desenvolvimento de um sistema de monitorizacao da ILC no
Hospital de Santa Marta (HSM), pretendeu-se realizar um estudo epidemiologico com o
objectivo principal de determinar a sua taxa de incidencia.
POPULACAO E METODOS
Desenho do Estudo: Estudo da coorte de doentes operados no servico de CCT do
HSM no periodo entre 1 de Julho e 30 de Novembro de 2008.
Criterios de exclusao: Foram excluidos os doentes cuja indicacao cirurgica tenha
sido a propria ILC e os doentes reoperados apos uma cirurgia primaria realizada antes do
inicio do estudo.
Projecto TILC
2
Tamanho da amostra: A dimensao da amostra foi determinada assumindo um
nivel de significancia de 0,05, uma prevalencia da ILC de 5% e uma precisao de 5 a 10
pontos percentuais do valor real. O numero calculado foi de 385 doentes, o qual
corresponderia a cerca de 4 meses de movimento cirurgico; porem, perante um menor
debito operatorio durante o periodo de ferias e a possibilidade de uma taxa de exclusao
superior aos 10% previstos por ausencia de dados de seguimento, optou-se pelo numero
de doentes operados em cinco meses no servico.
Recolha de dados e bases de dados: Foram recolhidos dois tipos de dados: um
geral, referente a populacao cirurgica do servico, obtido atraves de varios sistemas de
informacao; outro orientado para os casos de ILC, provenientes de uma folha especifica
preenchida directamente por um cirurgiao quando os doentes reuniram os criterios
necessarios para o diagnostico de ILC.
Analise e Resultados: A percentagem de incidencia (numero de doentes com
ILC/numero de doentes operado x 100) global da ILC foi de 4,57%, e a das ILC
diagnosticadas unicamente no hospital de 1,3%; as densidades de incidencia (No de ILC/
Dias de Internamento x 1000) foram, respectivamente de 2,53…
Advisors/Committee Members: Ferrinho, Paulo, Valadas, Emília, 1962-.
Subjects/Keywords: Surgical Site Infection; Incidence Rate; Registry
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APA ·
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APA (6th Edition):
Miranda, Luís Manuel Rabaça Pires Coutinho de, 1. (2010). Determinação da taxa de incidência da infecção do local cirúrgico no serviço de Cirurgia Cardiotorácica do Hospital de Santa Marta em 2008. (Thesis). Universidade de Lisboa. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/1919
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Miranda, Luís Manuel Rabaça Pires Coutinho de, 1959-. “Determinação da taxa de incidência da infecção do local cirúrgico no serviço de Cirurgia Cardiotorácica do Hospital de Santa Marta em 2008.” 2010. Thesis, Universidade de Lisboa. Accessed April 18, 2021.
http://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/1919.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Miranda, Luís Manuel Rabaça Pires Coutinho de, 1959-. “Determinação da taxa de incidência da infecção do local cirúrgico no serviço de Cirurgia Cardiotorácica do Hospital de Santa Marta em 2008.” 2010. Web. 18 Apr 2021.
Vancouver:
Miranda, Luís Manuel Rabaça Pires Coutinho de 1. Determinação da taxa de incidência da infecção do local cirúrgico no serviço de Cirurgia Cardiotorácica do Hospital de Santa Marta em 2008. [Internet] [Thesis]. Universidade de Lisboa; 2010. [cited 2021 Apr 18].
Available from: http://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/1919.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Miranda, Luís Manuel Rabaça Pires Coutinho de 1. Determinação da taxa de incidência da infecção do local cirúrgico no serviço de Cirurgia Cardiotorácica do Hospital de Santa Marta em 2008. [Thesis]. Universidade de Lisboa; 2010. Available from: http://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/1919
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Zambia
5.
Mukosai, Simon.
Pre-operative bladder irrigation with Povidone Iodine in reducing open prostatectomy surgical site infection(SSI) at University Teaching Hospital, Lusaka
.
Degree: 2013, University of Zambia
URL: http://hdl.handle.net/123456789/3154
► Objective:The study investigated the efficacy of using 1% povidone-iodine pre-operative bladder irrigation in reducing open prostatectomy surgical site infections at the University Teaching Hospital, Department…
(more)
▼ Objective:The study investigated the efficacy of using 1% povidone-iodine pre-operative bladder irrigation in reducing open prostatectomy surgical site infections at the University Teaching Hospital, Department of Surgery, Lusaka. Patients and Methods:One hundred and thirty patients were recruited from the waiting list of Urology unit II in the department of surgery during the period between July 2011 to December 2012. The patients were randomly allocated to each of the two groups using a non-probability convenient sampling method. Each group had 65 patients. Patients in the study group had their bladder irrigated with 1% 50cc povidone-iodine which was drained upon opening the bladder and open prostatectomy performed as per standard technique. In the control group povidone-iodine was not used. Both groups received pre-operative antibiotics 30 minutes before incision and post-operative for 5 days. Pre-operative, intraoperative and post-operative data were collected on a standardised data collection forms.Post-operative irrigation was done for 24 to 48 hours. After 9 to 12 days the catheter was removed as an out patient. Patients were followed up in the urological clinic at 1 week, 2 weeks and at 4 weeks post-operatively to assess whether they had developed surgical site infections according to CDC guidelines. Data were analysed using SPSS version 16.Results :The patients mean age was 71.1 in the control group and 71.4 in the study group with no statistically significant difference (t=0.318; p=0.75; df =126.89). The overall surgical infection rate was 16.2%. In the control group 15 out of 65 patients (23.1%) developed SSIs. While in the study group 6 out of 65 patients (9.2%) developed SSIs. The difference in the rates of SSI between the two groups was statistically significant (χ²; p<0.05; df=126.89) Escherichia coli was the most predominant organism 13/37 (35%), Streptococcus 7/37 (18.9%), Citrobacter koseri 5/37 (13.5%), Klebsiella sp 4/37 (10.8%). Escherichia coli, Streptococcus and Citrobacter were sensitive to ciprofloxacin; Pantoea agglomerans was sensitive to ceftazidime, while Staphylococcus coagulase was sensitive to imipenem. Enterobacter cloace was resistant to all antibiotics used.Conclusion:Irrigating the bladder with 1% povidone-iodine resulted in a significant lower rate of surgical site infections, reduced morbidity and post-operative hospital stay.
Subjects/Keywords: Prostatectomy Surgical Site Infection;
Surgical Infections;
Povidine Iodine
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APA ·
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MLA ·
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CSE |
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Manager
APA (6th Edition):
Mukosai, S. (2013). Pre-operative bladder irrigation with Povidone Iodine in reducing open prostatectomy surgical site infection(SSI) at University Teaching Hospital, Lusaka
. (Thesis). University of Zambia. Retrieved from http://hdl.handle.net/123456789/3154
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Mukosai, Simon. “Pre-operative bladder irrigation with Povidone Iodine in reducing open prostatectomy surgical site infection(SSI) at University Teaching Hospital, Lusaka
.” 2013. Thesis, University of Zambia. Accessed April 18, 2021.
http://hdl.handle.net/123456789/3154.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Mukosai, Simon. “Pre-operative bladder irrigation with Povidone Iodine in reducing open prostatectomy surgical site infection(SSI) at University Teaching Hospital, Lusaka
.” 2013. Web. 18 Apr 2021.
Vancouver:
Mukosai S. Pre-operative bladder irrigation with Povidone Iodine in reducing open prostatectomy surgical site infection(SSI) at University Teaching Hospital, Lusaka
. [Internet] [Thesis]. University of Zambia; 2013. [cited 2021 Apr 18].
Available from: http://hdl.handle.net/123456789/3154.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Mukosai S. Pre-operative bladder irrigation with Povidone Iodine in reducing open prostatectomy surgical site infection(SSI) at University Teaching Hospital, Lusaka
. [Thesis]. University of Zambia; 2013. Available from: http://hdl.handle.net/123456789/3154
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Cape Town
6.
Schuster, Delia.
Compliance with surgical antibiotic prophylaxis guidelines: a prospective descriptive study at a tertiary level hospital in Cape Town, South Africa.
Degree: MMed, Anaesthesia and Perioperative Medicine, 2020, University of Cape Town
URL: http://hdl.handle.net/11427/32965
► Background: The aim of surgical antibiotic prophylaxis (SAP) is to prevent surgical site infection (SSI) by administering an appropriate antimicrobial agent perioperatively. However, SAP may…
(more)
▼ Background: The aim of
surgical antibiotic prophylaxis (SAP) is to prevent
surgical site infection (SSI) by administering an appropriate antimicrobial agent perioperatively. However, SAP may be associated with adverse effects and incurs added costs. The primary objective of this prospective study is to establish whether clinicians are adhering to existing perioperative antibiotic prophylaxis guidelines in terms of indication, dosage and timing of SAP. Secondary objectives are to determine the proportion of patients receiving inappropriate antibiotics; and to evaluate correct practice concerning re-dosing and duration of SAP. Methods: A cross-sectional prospective audit of the anaesthetic records and prescription charts of
surgical patients was conducted at Groote Schuur Hospital, a tertiary level teaching hospital in Cape Town, South Africa, over a period of one week. Data were collected by anaesthetists – blinded to the study objectives – and the investigators; then captured on Excel spread sheets and compared to existing SAP guidelines. Descriptive statistics and binary logistic regression were used for analysis. Results: Of the 192 patients consented, 180 questionnaires were completed for data analysis. The median age of participants was 44.5 years (IQR: 31.5-58), with a preponderance of females (58.7%). SAP was administered in 149 cases (82.8%) and withheld in 31 (17.2%). This was appropriate in 91.9% (137/149) and 77.4% (24/31) respectively. Twelve patients (6.7%) received inappropriate antibiotics and in seven (3.9%) it was inappropriately withheld. Of the 156 patients who should have received SAP, choice of drug was correct in 121 (77.6%), dosage in 110 (70.5%) and timing in 87 (55.8%). Absolute compliance was achieved in 44.4% (80/180). Errors were mostly related to timing, re-dosing and duration of SAP. Conclusion: Anaesthetists and surgeons at Groote Schuur Hospital demonstrate variable adherence to
surgical antibiotic prophylaxis guidelines. Interventions aimed at improving compliance are warranted.
Advisors/Committee Members: Piercy, Jenna (advisor), Fagan Johannes (advisor).
Subjects/Keywords: surgical antibiotic prophylaxis; adherence; compliance; guidelines; surgical site infection
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APA (6th Edition):
Schuster, D. (2020). Compliance with surgical antibiotic prophylaxis guidelines: a prospective descriptive study at a tertiary level hospital in Cape Town, South Africa. (Thesis). University of Cape Town. Retrieved from http://hdl.handle.net/11427/32965
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Schuster, Delia. “Compliance with surgical antibiotic prophylaxis guidelines: a prospective descriptive study at a tertiary level hospital in Cape Town, South Africa.” 2020. Thesis, University of Cape Town. Accessed April 18, 2021.
http://hdl.handle.net/11427/32965.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Schuster, Delia. “Compliance with surgical antibiotic prophylaxis guidelines: a prospective descriptive study at a tertiary level hospital in Cape Town, South Africa.” 2020. Web. 18 Apr 2021.
Vancouver:
Schuster D. Compliance with surgical antibiotic prophylaxis guidelines: a prospective descriptive study at a tertiary level hospital in Cape Town, South Africa. [Internet] [Thesis]. University of Cape Town; 2020. [cited 2021 Apr 18].
Available from: http://hdl.handle.net/11427/32965.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Schuster D. Compliance with surgical antibiotic prophylaxis guidelines: a prospective descriptive study at a tertiary level hospital in Cape Town, South Africa. [Thesis]. University of Cape Town; 2020. Available from: http://hdl.handle.net/11427/32965
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of South Florida
7.
Gower, Sierra.
The Effect of Tight Glycemic Control on Surgical Site Infection Rates in Patients Undergoing Open Heart Surgery.
Degree: 2012, University of South Florida
URL: https://scholarcommons.usf.edu/etd/4325
► The purpose of this study was to investigate the effects of three different glycemic control conditions (tight, conventional, and standard) in the intraoperative period on:…
(more)
▼ The purpose of this study was to investigate the effects of three different glycemic control conditions (tight, conventional, and standard) in the intraoperative period on: 1) postoperative surgical site infections, and 2) postoperative procalcitonin, and C-reactive protein levels in patients undergoing open-heart surgery. Secondary aims of the study were to investigate the effects of the three glycemic treatment conditions on: 1) intraoperative blood glucose; 2) intraoperative glycemic stability; and 3) intensive care unit length of stay, in patients undergoing open-heart surgery.
An experimental design with a multilevel, single factor, within-subjects design was utilized. Patients were nested within anesthesia provider teams. The design was counterbalanced by means of a Latin square, where each of three anesthesia provider teams dispensed each of three glycemic control conditions once. Thirty-seven participants were randomized to either tight glycemic control (n =15), which maintained blood glucose 110-149 mg/dl via continuous intravenous insulin infusion, conventional glycemic control (n = 11), which maintained blood glucose 150-180 mg/dl via continuous intravenous insulin infusion, or standard glycemic control (n =11) which maintain blood glucose 150-180 mg/dl via intravenous bolus injections of insulin.
The main findings of this study were that there were no significant differences between the three glycemic interventional treatment groups in 1) thirty-day surgical site infections, 2) postoperative C-reactive protein or procalcitonin concentrations 3) intensive care unit length of stay, 4) intraoperative blood glucose levels, or 5) glycemic stability. An association between intraoperative peak blood glucose and surgical site infection was established. Participants that experienced higher peak blood glucose levels intraoperatively exhibited increased surgical site infections. Procalcitonin levels were significantly elevated in participants that experienced a surgical site infection, but C-reactive protein showed no significant difference between participants with or without a surgical site infection. Coronary artery bypass graft surgery concomitant with valve replacement surgery was associated with a higher rate of surgical site infections compared coronary artery bypass graft surgery or valve surgery independently.
In conclusion, an association was found between higher peak intraoperative blood glucose levels and increased surgical site infections, therefore maintaining intraoperative blood glucose levels below 180 mg/dl via a continuous intravenous infusion of insulin, may reduce postoperative surgical site infections in the open-heart patient. The use of tight glycemic control during the intraoperative period can be achieved safely, with the use of judicious protocols, but its benefits remain unproven. Inflammatory biomarker procalcitonin was predictive of infection, where C-reactive protein was not. The addition of procalcitonin to routine postoperative blood work, in open-heart patients, may benefit…
Subjects/Keywords: Cardiac Surgery; Hyperglycemia; Postoperative Wound Infection; Surgical Site Infection; Medicine and Health Sciences; Nursing
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APA (6th Edition):
Gower, S. (2012). The Effect of Tight Glycemic Control on Surgical Site Infection Rates in Patients Undergoing Open Heart Surgery. (Thesis). University of South Florida. Retrieved from https://scholarcommons.usf.edu/etd/4325
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Gower, Sierra. “The Effect of Tight Glycemic Control on Surgical Site Infection Rates in Patients Undergoing Open Heart Surgery.” 2012. Thesis, University of South Florida. Accessed April 18, 2021.
https://scholarcommons.usf.edu/etd/4325.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Gower, Sierra. “The Effect of Tight Glycemic Control on Surgical Site Infection Rates in Patients Undergoing Open Heart Surgery.” 2012. Web. 18 Apr 2021.
Vancouver:
Gower S. The Effect of Tight Glycemic Control on Surgical Site Infection Rates in Patients Undergoing Open Heart Surgery. [Internet] [Thesis]. University of South Florida; 2012. [cited 2021 Apr 18].
Available from: https://scholarcommons.usf.edu/etd/4325.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Gower S. The Effect of Tight Glycemic Control on Surgical Site Infection Rates in Patients Undergoing Open Heart Surgery. [Thesis]. University of South Florida; 2012. Available from: https://scholarcommons.usf.edu/etd/4325
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
8.
Gabrielle Meriche Galvão Bento da Silva Guatura.
Vigilância pós-alta em infecção de sítio cirúrgico: criação e validação de um instrumento.
Degree: 2017, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/7/7139/tde-05112018-115921/
► Introdução: A infecção de sítio cirúrgico representa a terceira causa de infecção relacionada à assistência à saúde, que mais acomete pacientes na Europa e no…
(more)
▼ Introdução: A infecção de sítio cirúrgico representa a terceira causa de infecção relacionada à assistência à saúde, que mais acomete pacientes na Europa e no Brasil. Considerando as altas hospitalares cada vez mais precoces e que grande parte das infecções do sítio cirúrgico se manifestará até o sétimo dia após a cirurgia, a vigilância pós-alta se faz extremamente necessária, uma vez que sua não realização pode levar a subnotificação, dificultando as ações de prevenção e controle. Existe carência, até o momento, de ferramentas que tenham sido validadas para a identificação de potenciais casos de ISC durante a vigilância pós-alta. Objetivo: Criar e validar um instrumento para a detecção pós-alta de potenciais casos de ISC. Método: Estudo psicométrico para a criação e validação de um instrumento, empregando-se as etapas de validação de conteúdo, critério e constructo. Resultado: O instrumento, após validação de conteúdo com juízes especialistas,
apresentou coeficiente de validade de conteúdo total igual a 0,87. Para a validação de critério e constructo o instrumento proposto foi aplicado em uma amostra de 100 pacientes e comparado ao exame físico por profissional de saúde, observando-se coeficiente alfa de Cronbach igual a 0,87; Kappa de Cohen igual a 0,83; sensibilidade igual a 76,4%; especificidade de 100%; valores preditivo negativo de 92,5%, e preditivo positivo igual a 100%; precisão de 94%. Conclusão: O instrumento proposto foi validado e demonstrou ser uma ferramenta útil para detecção de possíveis casos de infecção de sítio cirúrgico na vigilância pós-alta.
Introduction: Surgical site infection (SSI) represents the third cause of healthcare-associated infections, which affects patients in Europe and Brazil. Considering hospital discharges that are becoming more precocious and that most SSI will manifest themselves up to the seventh postoperative day, postdischarge surveillance is extremely necessary, since its
failure to perform can lead to underreporting, making it difficult to prevention and control actions. There is a lack, until now, of tools that have been validated for the identification of potential cases of SSI during postdischarge surveillance. Objective: To create and validate an instrument for the postdischarge surveillance of potential SSI cases. Method: a psychometric study for the creation and validation of an instrument, using content, criterion and construct validation. Result: The instrument, after validating content with expert judges, presented coefficient of total content validity equal to 0.87. For the validation of criterion and construct the instrument was applied in a sample of 100 patients. Comparing the instrument to the physical examination by the health professional, Cronbachs Alpha was equal to 0.87; Cohen\'s Kappa was equal to 0.83; sensitivity equal to 76.4%; specificity of 100%; negative predictive values of 92.5%, and, positive predictive equal to 100%. The
accuracy of the instrument was 94%. Conclusion: The proposed instrument was validated and constitutes a useful…
Advisors/Committee Members: Vanessa de Brito Poveda, Erika Christiane Marocco Duran, Camila Mendonça de Moraes Lopes, Ruth Natalia Teresa Turrini.
Subjects/Keywords: Enfermagem; Estudo de validação; Infecção da ferida operatória; Infecção nosocomial; Cross infection; Nursing; Surgical wound infection; Validation studies
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APA (6th Edition):
Guatura, G. M. G. B. d. S. (2017). Vigilância pós-alta em infecção de sítio cirúrgico: criação e validação de um instrumento. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/7/7139/tde-05112018-115921/
Chicago Manual of Style (16th Edition):
Guatura, Gabrielle Meriche Galvão Bento da Silva. “Vigilância pós-alta em infecção de sítio cirúrgico: criação e validação de um instrumento.” 2017. Masters Thesis, University of São Paulo. Accessed April 18, 2021.
http://www.teses.usp.br/teses/disponiveis/7/7139/tde-05112018-115921/.
MLA Handbook (7th Edition):
Guatura, Gabrielle Meriche Galvão Bento da Silva. “Vigilância pós-alta em infecção de sítio cirúrgico: criação e validação de um instrumento.” 2017. Web. 18 Apr 2021.
Vancouver:
Guatura GMGBdS. Vigilância pós-alta em infecção de sítio cirúrgico: criação e validação de um instrumento. [Internet] [Masters thesis]. University of São Paulo; 2017. [cited 2021 Apr 18].
Available from: http://www.teses.usp.br/teses/disponiveis/7/7139/tde-05112018-115921/.
Council of Science Editors:
Guatura GMGBdS. Vigilância pós-alta em infecção de sítio cirúrgico: criação e validação de um instrumento. [Masters Thesis]. University of São Paulo; 2017. Available from: http://www.teses.usp.br/teses/disponiveis/7/7139/tde-05112018-115921/
University of Ghana
9.
Alormenyo, N.M.
Trends and Determinants of Nosocomial Infection among Hospitalised Patients at Koforidua Regional Hospital.
Degree: 2019, University of Ghana
URL: http://ugspace.ug.edu.gh/handle/123456789/32894
► Background Nosocomial infections are a major public health problem worldwide and are on the increase despite significant efforts by hospital infection control measures. Nosocomial infection…
(more)
▼ Background
Nosocomial infections are a major public health problem worldwide and are on the increase
despite significant efforts by hospital infection control measures. Nosocomial infection
comprises infection occurring in a patient who is receiving treatment in a health care settings.
Infection acquired by health care workers and people visiting the hospital is considered
nosocomial infection. These infections affect about 2 million people globally resulting in 5% to
15% of them spending longer stay days in the hospital. In sub-Saharan Africa, incidence of
nosocomial infections ranges from 2-49% with patients in intensive care units having up to
35.6%.
Objectives. The objectives of this study were to provide an understanding of the trends and
factors associated with nosocomial infection and also to identify the causative agents of these
infections by tracing them in the microbial records for the past three years.
Methods. Electronic data of all patients who were admitted and went through any invasive
procedures at Koforidua Regional Hospital between the years 2016-2018 were reviewed. Any
post –surgery purulent discharges, abscess, and inflammation at the site of surgery, positive urine
culture of about 1 or 2 species with at least 10 bacteria / ml with or without clinical manifestation
after catheterization were included in the study. Again, respiratory signs such as couth, purulent
sputum, new infiltrate on the chest and radiography consistent with infection after or during
tracheotomy and any inflammation, lymphagitis and purulent discharges at the site of vascular
puncture, cepticaemia, fever, rigor and at least one positive blood culture suffered by a patient
University were also included in the study. All patients of different ages and sex group that went through
any invasive procedures in the hospital within the year under review were included.
Results. The results from the study showed a 1.2% prevalence of nosocomial infection in
Koforidua Regional hospital.
It was also observed from the results that patients whose ages were more than 40 years had a
nosocomial infection prevalence ranging from 1.2% to 2.1%. With the trends of infection by
number of days hospitalized, it was found that patients who were on admission for less than 13
days had infection prevalence between 1% to 4.5% as compared to 13.6 % for patients who were
admitted for more than 14 days. In the environment where service was provided, results showed
9.75% infection prevalence at the ICU, 1.49% in female surgical ward and 0.95% in male
surgical ward. With the payment methods, results revealed 0.82% infection prevalence for
patients who used cash to pay for health service delivery by themselves and 1.37% for patients
who depended on the National Health Insurance Scheme (NHIS) for payment. Finally,
staphylococcus and streptococcus were found to be the most prevalent nosocomial bacteria in the
facility.
In conclusion, the more a person aged, the more the immunity reduced…
Subjects/Keywords: Nosocomial Infection;
Koforidua Regional Hospital
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Manager
APA (6th Edition):
Alormenyo, N. M. (2019). Trends and Determinants of Nosocomial Infection among Hospitalised Patients at Koforidua Regional Hospital.
(Masters Thesis). University of Ghana. Retrieved from http://ugspace.ug.edu.gh/handle/123456789/32894
Chicago Manual of Style (16th Edition):
Alormenyo, N M. “Trends and Determinants of Nosocomial Infection among Hospitalised Patients at Koforidua Regional Hospital.
” 2019. Masters Thesis, University of Ghana. Accessed April 18, 2021.
http://ugspace.ug.edu.gh/handle/123456789/32894.
MLA Handbook (7th Edition):
Alormenyo, N M. “Trends and Determinants of Nosocomial Infection among Hospitalised Patients at Koforidua Regional Hospital.
” 2019. Web. 18 Apr 2021.
Vancouver:
Alormenyo NM. Trends and Determinants of Nosocomial Infection among Hospitalised Patients at Koforidua Regional Hospital.
[Internet] [Masters thesis]. University of Ghana; 2019. [cited 2021 Apr 18].
Available from: http://ugspace.ug.edu.gh/handle/123456789/32894.
Council of Science Editors:
Alormenyo NM. Trends and Determinants of Nosocomial Infection among Hospitalised Patients at Koforidua Regional Hospital.
[Masters Thesis]. University of Ghana; 2019. Available from: http://ugspace.ug.edu.gh/handle/123456789/32894
Freie Universität Berlin
10.
Piening, Brar Christian.
Seasonal variations of nosocomial infections.
Degree: 2011, Freie Universität Berlin
URL: http://dx.doi.org/10.17169/refubium-12624
► For many infectious diseases, seasonal variations in incidence are known, but it has not yet been investigated extensively and systematically whether these variations also exist…
(more)
▼ For many infectious diseases, seasonal variations in incidence are known, but
it has not yet been investigated extensively and systematically whether these
variations also exist in
nosocomial infections. This is important because
seasonal fluctuations should be considered relevant in the planning of studies
on
infection control and may result in seasonal adjustments of
infection
control measures. This study was performed in order to determine seasonal
variations in the incidence density of
nosocomial infections and their most
important pathogens. For this purpose, the national reference database for the
surveillance of
nosocomial infections in intensive care patients (ICU-KISS)
and operated patients (OP-KISS) of the German hospital
infection surveillance
system (KISS) was analyzed for the period from January 2000 to December 2009.
The definition of the seasons was based on freely available climate data from
the German weather service "Deutscher Wetterdienst". For ICU-KISS, incidence
densities (infections/1000 patient-days) and incidence density ratios, for OP-
KISS incidences (infections/100 operated patients) and relative risks, were
calculated respectively with the 95% confidence intervals. The analysis was
based on 8,680,283 patient-days and 42,603 infections from 597 intensive care
units and 767,970 operated patients and 13,586
surgical site infections in 595
surgical departments. The results showed both a significant increase in
primary sepsis in the summer period (incidence density ratio 1.10 [1.05 to
1.16]) and a significant decrease in winter period (incidence density ratio
0.89 [0.84 -0.94]) and also a significant increase in lower respiratory tract
infections in the summer period (incidence density ratio 1.08 [1.05 to 1.12])
and a significant decrease in winter (incidence density ratio 0.96 [0.93
-0.999]) period. The
surgical site infections also showed a significant
increase in summer (relative risk 1.11 [1.06 to 1.15]) and a significant
decrease in winter (relative risk 0.95 [0.91 to 0.99]). Among the most
important pathogens of
nosocomial infections nonfermenting bacteria such as
pseudomonas aeruginosa and acinetobacter baumannii, enterobacteria such as
enterobacter spp. and klebsiella spp. and some other pathogens were identified
as seasonal infectious agents. The finding that seasonal effects exist in
nosocomial infections makes it necessary to consider these effects in the
planning, implementation and evaluation of studies. Since the extent of
seasonal effects is relatively low, further studies will be necessary to
evaluate the effect of the introduction of seasonally adjusted hygiene
measures.
Advisors/Committee Members: m (gender), Prof. Dr. H. Rüden (firstReferee), PD Dr. M. Deja (furtherReferee), Prof. Dr. S. Lemmen (furtherReferee).
Subjects/Keywords: noscomial infection; surgical site infection; hospital aquired infection; seasonality; incidence; incidence density; 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
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APA (6th Edition):
Piening, B. C. (2011). Seasonal variations of nosocomial infections. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-12624
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Piening, Brar Christian. “Seasonal variations of nosocomial infections.” 2011. Thesis, Freie Universität Berlin. Accessed April 18, 2021.
http://dx.doi.org/10.17169/refubium-12624.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Piening, Brar Christian. “Seasonal variations of nosocomial infections.” 2011. Web. 18 Apr 2021.
Vancouver:
Piening BC. Seasonal variations of nosocomial infections. [Internet] [Thesis]. Freie Universität Berlin; 2011. [cited 2021 Apr 18].
Available from: http://dx.doi.org/10.17169/refubium-12624.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Piening BC. Seasonal variations of nosocomial infections. [Thesis]. Freie Universität Berlin; 2011. Available from: http://dx.doi.org/10.17169/refubium-12624
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Georgia State University
11.
Beaulieu, Brooke.
Surgical Site Infections Following Total Joint Arthroplasty: An Examination of Microbial Isolates, Predisposing Patient Factors, and Diagnostic Delay.
Degree: MPH, Public Health, 2015, Georgia State University
URL: https://scholarworks.gsu.edu/iph_theses/399
► Background: Although device-associated total joint arthroplasty (TJA) has the potential to greatly improve recipient quality of life, the occurrence of surgical site infection (SSI)…
(more)
▼ Background: Although device-associated total joint arthroplasty (TJA) has the potential to greatly improve recipient quality of life, the occurrence of
surgical site infection (SSI) thereafter can render drastically debilitating and costly consequences.
Methods: A retrospective cohort design was used to analyze hospital discharge data from the State Inpatient Database (State of California, years 2009-2011). Descriptive statistics were conducted to establish microbial prevalence and multivariate logistic regression was conducted to examine associations between various patient-centric risk factors and the development of SSI. Interaction terms were evaluated for model inclusion. Finally, elapsed time from TJA operation to
infection diagnosis was assessed according to
site of TJA, pathogen virulence, and pre-existing comorbidities.
Results: During retrospective review, 1769 infections were detected. The incident rate of
infection was 2.70 infections per 100,000 person-days. Staphylococci species were the most prevalent microorganisms (79%), including methicillin-resistant
S. aureus (MRSA 24%) and methicillin-susceptible
S. aureus (MSSA 40%). Polymicrobial aetiology was identified in 5% of infections. The multivariate logistic model revealed increased odds of
infection for knee vs. hip operations (OR = 1.50; 95% CI = 1.41 – 1.60), for male sex (OR = 1.70; 95% CI = 1.60 – 1.80), for increasing length of hospitalization (OR = 1.10; 95% CI = 1.09 – 1.11), and for comorbidities including obesity (OR = 3.99; 95% CI = 3.16 – 5.04), diabetes (OR = 1.45; 95% CI = 1.29 – 1.63), and rheumatoid arthritis (OR = 1.49; 95% CI = 1.19 – 1.87). Diagnostic delay differed significantly according to pathogen virulence, but not with comorbid status and
site of TJA.
Conclusions: Staphylococci species were the most prevalent microbes identified in infected patients. Anatomical
site of TJA, male sex, length of hospitalization, and existing comorbidities were significantly associated with increased odds of
surgical site infection following operative TJA. Surveillance networks continue to be fundamental for understanding and reducing the burden of SSI as a subset of healthcare-associated infections.
Advisors/Committee Members: Richard Rothenberg, MD MPH, Betty S. Lai, PhD.
Subjects/Keywords: surgical-site infection; surveillance; healthcare-associated infections; microbial prevalence
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APA (6th Edition):
Beaulieu, B. (2015). Surgical Site Infections Following Total Joint Arthroplasty: An Examination of Microbial Isolates, Predisposing Patient Factors, and Diagnostic Delay. (Thesis). Georgia State University. Retrieved from https://scholarworks.gsu.edu/iph_theses/399
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Beaulieu, Brooke. “Surgical Site Infections Following Total Joint Arthroplasty: An Examination of Microbial Isolates, Predisposing Patient Factors, and Diagnostic Delay.” 2015. Thesis, Georgia State University. Accessed April 18, 2021.
https://scholarworks.gsu.edu/iph_theses/399.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Beaulieu, Brooke. “Surgical Site Infections Following Total Joint Arthroplasty: An Examination of Microbial Isolates, Predisposing Patient Factors, and Diagnostic Delay.” 2015. Web. 18 Apr 2021.
Vancouver:
Beaulieu B. Surgical Site Infections Following Total Joint Arthroplasty: An Examination of Microbial Isolates, Predisposing Patient Factors, and Diagnostic Delay. [Internet] [Thesis]. Georgia State University; 2015. [cited 2021 Apr 18].
Available from: https://scholarworks.gsu.edu/iph_theses/399.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Beaulieu B. Surgical Site Infections Following Total Joint Arthroplasty: An Examination of Microbial Isolates, Predisposing Patient Factors, and Diagnostic Delay. [Thesis]. Georgia State University; 2015. Available from: https://scholarworks.gsu.edu/iph_theses/399
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Rhode Island College
12.
Desjardins, Ashley E.
Does Prophylactic Antibiotic Administration Time Effect Surgical Site Infection Rates in Colorectal Surgery?.
Degree: MSN, 2016, Rhode Island College
URL: https://digitalcommons.ric.edu/etd/169
► Colorectal surgery is known for having a high risk of surgical site infection (SSI). Prior research has suggested that administering prophylactic antibiotics prior to…
(more)
▼ Colorectal surgery is known for having a high risk of surgical site infection (SSI). Prior research has suggested that administering prophylactic antibiotics prior to colorectal surgery may prevent SSI. This led to the question: In adult surgical patients having colorectal surgeries, does prophylactic antibiotic administration time effect surgical site infection rates within 30 days of surgery? A comprehensive literature review was completed followed by a detailed screening for inclusion and exclusion criteria, resulting in a final total of nine studies. Detailed data were collected for each study, followed by completion of critical appraisal checklists appropriate to the study design. Quality of the evidence was assessed across studies. Six of the studies were cohort studies, with only two randomized controlled trials and one systematic review. Results indicated that there is insufficient evidence to support a definite course of action for timing of antibiotic prophylaxis for colorectal surgery. The certified registered nurse anesthetist (CRNA) should be aware of the recommendations to administer antibiotics for colorectal surgery before the surgical incision based on the results of this systematic review as timing of administration can affect SSI rates. It is recommended to carefully consider antibiotic selection and timing when administering antibiotics for colorectal surgery.
Subjects/Keywords:
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APA (6th Edition):
Desjardins, A. E. (2016). Does Prophylactic Antibiotic Administration Time Effect Surgical Site Infection Rates in Colorectal Surgery?. (Masters Thesis). Rhode Island College. Retrieved from https://digitalcommons.ric.edu/etd/169
Chicago Manual of Style (16th Edition):
Desjardins, Ashley E. “Does Prophylactic Antibiotic Administration Time Effect Surgical Site Infection Rates in Colorectal Surgery?.” 2016. Masters Thesis, Rhode Island College. Accessed April 18, 2021.
https://digitalcommons.ric.edu/etd/169.
MLA Handbook (7th Edition):
Desjardins, Ashley E. “Does Prophylactic Antibiotic Administration Time Effect Surgical Site Infection Rates in Colorectal Surgery?.” 2016. Web. 18 Apr 2021.
Vancouver:
Desjardins AE. Does Prophylactic Antibiotic Administration Time Effect Surgical Site Infection Rates in Colorectal Surgery?. [Internet] [Masters thesis]. Rhode Island College; 2016. [cited 2021 Apr 18].
Available from: https://digitalcommons.ric.edu/etd/169.
Council of Science Editors:
Desjardins AE. Does Prophylactic Antibiotic Administration Time Effect Surgical Site Infection Rates in Colorectal Surgery?. [Masters Thesis]. Rhode Island College; 2016. Available from: https://digitalcommons.ric.edu/etd/169
13.
McCoy, Keri.
A Preoperative Hand Hygiene Campaign: " No One Left BeHand.".
Degree: MSN, 2020, University of San Francisco
URL: https://repository.usfca.edu/capstone/1049
► Abstract Problem: Surgical site infections (SSIs) account for 20% of all hospital-acquired infections (HAIs). Performance of consistent, accurate hand hygiene practices by healthcare workers…
(more)
▼ Abstract
Problem: Surgical site infections (SSIs) account for 20% of all hospital-acquired infections (HAIs). Performance of consistent, accurate hand hygiene practices by healthcare workers is the most effective means of preventing infection, yet the average compliance rates remain low. The preoperative (PREOP) unit carries tremendous responsibility for decreasing each patient's risk for SSI by adequately following the World Health Organization (WHO) guidelines for hand hygiene. The PREOP remains at a low average hand hygiene compliance rate of 69%, with decreased consistency, frequency, and knowledge deficit of hygiene practices. The aim of the quality improvement (QI) hand hygiene campaign is to increase compliance among the PREOP registered nurses (RNs) and patient care technicians (PCTs) to promote infection control and decrease the risk of SSIs.
Context: The PREOP serves multiple specialties with an average of 45 cases a day. The PREOP unit can significantly contribute to the reduction of SSIs with strict adherence to hand hygiene protocols. The RNs and PCTs provide direct patient care measures to several disciplines, including orthopedic, podiatry, head and neck, general surgery, gynecological, and urology surgery patients. A fast-paced work environment, lack of time, and low morale were listed as barriers to hand hygiene adherence. An SSI, on average, costs $30,000 for just one case. Diminishing the knowledge deficit by using WHO guidelines and improving overall cleanliness are the most influential factors for maintaining collaboration to support the efforts of reducing a patient's risk of SSI.
Interventions: The QI project involves the implementation of a multidisciplinary PREOP hand hygiene campaign using a multimodal approach over a single intervention strategy. The interventions include (a) hands-on training and education; (b) campaign slogan, signs, and songs; (c) daily direct observation audits and huddles to discuss barriers; (d) monthly secret observer audits; (e) RN and PCT scripting; (f) increasing access to supplies; (g) PREOP RN process map; and (h) patient prompting tools.
Measures: The outcome measures are the results of the daily direct observation audits by the champions and mangers, and the monthly secret observer audits by the quality department. The hand hygiene knowledge quizzes for staff and the patient participation tool survey are the two process measures. The balancing measure is the monthly tracking of the average PREOP RN patient preparation times using the electronic health documentation system.
Results: The PREOP hand hygiene campaign has reached a 13% increase in RN and PCT hand hygiene compliance within four months. Combined direct observation audits by champions and secret observations by the quality department revealed an 82% average compliance rate. Quiz scores have improved from 76% to…
Subjects/Keywords: Hand Hygiene; Preoperative; Surgical Site Infection; Perioperative, Operating Room and Surgical Nursing
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APA (6th Edition):
McCoy, K. (2020). A Preoperative Hand Hygiene Campaign: " No One Left BeHand.". (Thesis). University of San Francisco. Retrieved from https://repository.usfca.edu/capstone/1049
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
McCoy, Keri. “A Preoperative Hand Hygiene Campaign: " No One Left BeHand.".” 2020. Thesis, University of San Francisco. Accessed April 18, 2021.
https://repository.usfca.edu/capstone/1049.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
McCoy, Keri. “A Preoperative Hand Hygiene Campaign: " No One Left BeHand.".” 2020. Web. 18 Apr 2021.
Vancouver:
McCoy K. A Preoperative Hand Hygiene Campaign: " No One Left BeHand.". [Internet] [Thesis]. University of San Francisco; 2020. [cited 2021 Apr 18].
Available from: https://repository.usfca.edu/capstone/1049.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
McCoy K. A Preoperative Hand Hygiene Campaign: " No One Left BeHand.". [Thesis]. University of San Francisco; 2020. Available from: https://repository.usfca.edu/capstone/1049
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
14.
Topaktaş, Dilek.
Ameliyat olan hastalarda cerrahi alan enfeksiyonu gelişimini etkileyen faktörlerin incelenmesi
.
Degree: ESOGÜ, Sağlık Bilimleri Fakültesi, Hemşirelik, 2019, Eskisehir Osmangazi University
URL: http://hdl.handle.net/11684/1861
► Amaç: Bu araştırma, ameliyat geçiren hastalarda Cerrahi Alan Enfeksiyonu (CAE) gelişimini etkileyen faktörlerin incelenmesi amacıyla yapılmıştır. Gereç-yöntem: Araştırma, Şubat 2018 - Eylül 2018 tarihleri arasında…
(more)
▼ Amaç: Bu araştırma, ameliyat geçiren hastalarda Cerrahi Alan Enfeksiyonu (CAE) gelişimini etkileyen faktörlerin incelenmesi amacıyla yapılmıştır.
Gereç-yöntem: Araştırma, Şubat 2018 - Eylül 2018 tarihleri arasında Eskişehir Osmangazi Üniversitesi Sağlık Uygulama ve Araştırma Hastanesi (ESOGÜ) Cerrahi Kliniklerinde ve Kütahya Sağlık Bilimleri Üniversitesi Evliya Çelebi Eğitim ve Araştırma Hastanesi (KSBÜEÇEAH) Cerrahi Kliniklerinde yürütülmüştür. Araştırmanın evreni ESOGÜ ve KSBÜEÇEAH Cerrahi Servislerinde ameliyat olan hastalardır. Örneklem seçimine gidilmemiş olup, Şubat 2018-Eylül 2018 tarihleri arasında ameliyat olan ve sonrasında CAE gelişmiş hastaların tamamına ulaşılmaya çalışılmıştır. Bilinci açık, iletişim sorunu olmayan ve araştırmaya katılmayı kabul eden tüm hastalar (n=108) çalışmaya dahil edilmiştir. Araştırmanın verileri, araştırmacı tarafından hazırlanan hastaların sosyo-demografik ve predispozan faktörlere ilişkin bilgilerini içeren Hasta Bilgi Formu ile toplanmıştır. Araştırma verilerinin değerlendirilmesinde sayı, yüzde gibi tanımlayıcı istatistiklerden yararlanılmıştır.
Bulgular: Hastalarının yaş ortalaması 52.75±6.91 olup, hastanede yatış süresi ortalama 12.68±3.42 gündür. Hastalar, % 53.70 oranında genel cerrahi kliniğinde yatmakta olduğu, %45,37 oranında temiz-kontamine yara geliştiği; gelişen enfeksiyon türünün ise %59,26’sı yüzeyel-insizyonel Cerrahi alan enfeksiyonu olduğu belirlenmiştir. Hastalarda yaşın, ameliyat süresinin, diyabetin, sigara kullanımının beden kitle indeksi’nin, steroid kullanımının, komşu enfeksiyon varlığının ve mobilizasyon süresinin Cerrahi Alan Enfeksiyonu gelişiminde etkili olduğu saptanmıştır.
Sonuç: Cerrahi alan enfeskiyonlarının gelişiminde bireysel özellikler, cerrahi süreç ile ilgili özellikler ve çevresel faktörler etkilidir. Önlenebilmesi için tüm sağlık çalışanlarının birlikte kanıta dayalı yaklaşımları uygulamada kullanmaları önemlidir. Hemşirelerin Cerrahi alan enfeksiyonunu önlemede ameliyat öncesi, sırası ve sonrasında önemli sorumlulukları vardır.
Advisors/Committee Members: Köşgeroğlu, Nedime (advisor).
Subjects/Keywords: Cerrahi Alan Enfeksiyonu;
Cerrahi Hastaları;
Hemşire;
Surgical Site Infection;
Surgical Patients;
Nurse
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APA ·
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APA (6th Edition):
Topaktaş, D. (2019). Ameliyat olan hastalarda cerrahi alan enfeksiyonu gelişimini etkileyen faktörlerin incelenmesi
. (Thesis). Eskisehir Osmangazi University. Retrieved from http://hdl.handle.net/11684/1861
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Topaktaş, Dilek. “Ameliyat olan hastalarda cerrahi alan enfeksiyonu gelişimini etkileyen faktörlerin incelenmesi
.” 2019. Thesis, Eskisehir Osmangazi University. Accessed April 18, 2021.
http://hdl.handle.net/11684/1861.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Topaktaş, Dilek. “Ameliyat olan hastalarda cerrahi alan enfeksiyonu gelişimini etkileyen faktörlerin incelenmesi
.” 2019. Web. 18 Apr 2021.
Vancouver:
Topaktaş D. Ameliyat olan hastalarda cerrahi alan enfeksiyonu gelişimini etkileyen faktörlerin incelenmesi
. [Internet] [Thesis]. Eskisehir Osmangazi University; 2019. [cited 2021 Apr 18].
Available from: http://hdl.handle.net/11684/1861.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Topaktaş D. Ameliyat olan hastalarda cerrahi alan enfeksiyonu gelişimini etkileyen faktörlerin incelenmesi
. [Thesis]. Eskisehir Osmangazi University; 2019. Available from: http://hdl.handle.net/11684/1861
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Colorado State University
15.
Ruple-Czerniak, Audrey.
Nosocomial infection rates in veterinary referral hospitals: using syndromic surveillance to establish baseline rates.
Degree: MS(M.S.), Clinical Sciences, 2011, Colorado State University
URL: http://hdl.handle.net/10217/70824
► Nosocomial, or hospital-acquired, infections are considered to be the most common complication affecting hospitalized human patients, but their impact on hospitalized veterinary patients is less…
(more)
▼ Nosocomial, or hospital-acquired, infections are considered to be the most common complication affecting hospitalized human patients, but their impact on hospitalized veterinary patients is less well understood. In fact, the incidence of
nosocomial infections that occur in veterinary hospitals has not been established. There is evidence, however, that
nosocomial infections are of great consequence in veterinary medicine and can have considerable negative effects on the individual patient as well as on the veterinary hospital as a whole. Due to the increased risk of
infection in hospitalized patients, it is anticipated that some
nosocomial infections will occur. Establishing a baseline rate of
infection using surveillance techniques will allow investigators to ascertain the proportion of infections that can be prevented using
infection control measures. The purpose of this study was to establish baseline rates of
infection using a syndromic surveillance system created for implementation in small animal and equine referral hospitals. This study included weaned dogs, cats, and horses (n=2248) that were hospitalized in the critical care unit of one of five participating veterinary hospitals during a 12 week period in 2006. Clinicians actively performed syndromic surveillance on hospitalized patients and reported their results no later than the time of the patient’s discharge from the hospital. Adjusted rates of
nosocomial events were estimated using Poisson regression, and risk factors associated with an increased risk of developing a
nosocomial event were analyzed using multivariable logistic regression. Adjusting for hospital of admission, 19.7% of horses, 16.3% of dogs, and 12% of cats included in this study were reported to have experienced a
nosocomial event occur during hospitalization. The only risk factor found to have a positive association with the development of a
nosocomial event in all three species was placement of a urinary catheter.
Surgical site inflammation and intravenous catheter
site inflammation were two of the most commonly reported events across all species. Results of this study suggest that
nosocomial event rates can be established using syndromic surveillance systems in multiple hospitals. Data pertinent to risk factors for the occurrence of
nosocomial events can also be effectively collected using the same technique. Further research is warranted in order to evaluate how generalizable these results are to other veterinary healthcare settings.
Advisors/Committee Members: Morley, Paul S. (advisor), Lunn, Katharine F. (committee member), Peel, Jennifer L. (committee member), Van Metre, David C. (committee member).
Subjects/Keywords: hospital-associated infection; nosocomial infection; nosocomial infection rates; risk factor; syndromic surveillance; veterinary
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APA ·
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APA (6th Edition):
Ruple-Czerniak, A. (2011). Nosocomial infection rates in veterinary referral hospitals: using syndromic surveillance to establish baseline rates. (Masters Thesis). Colorado State University. Retrieved from http://hdl.handle.net/10217/70824
Chicago Manual of Style (16th Edition):
Ruple-Czerniak, Audrey. “Nosocomial infection rates in veterinary referral hospitals: using syndromic surveillance to establish baseline rates.” 2011. Masters Thesis, Colorado State University. Accessed April 18, 2021.
http://hdl.handle.net/10217/70824.
MLA Handbook (7th Edition):
Ruple-Czerniak, Audrey. “Nosocomial infection rates in veterinary referral hospitals: using syndromic surveillance to establish baseline rates.” 2011. Web. 18 Apr 2021.
Vancouver:
Ruple-Czerniak A. Nosocomial infection rates in veterinary referral hospitals: using syndromic surveillance to establish baseline rates. [Internet] [Masters thesis]. Colorado State University; 2011. [cited 2021 Apr 18].
Available from: http://hdl.handle.net/10217/70824.
Council of Science Editors:
Ruple-Czerniak A. Nosocomial infection rates in veterinary referral hospitals: using syndromic surveillance to establish baseline rates. [Masters Thesis]. Colorado State University; 2011. Available from: http://hdl.handle.net/10217/70824
16.
Aires, Ernestina.
Avaliação de custos associados à infeção do local cirúrgico nos serviços de cirurgia geral dos Hospital geral Santo António.
Degree: 2011, RCAAP
URL: http://www.rcaap.pt/detail.jsp?id=oai:repositorio.ucp.pt:10400.14/8820
► O custo económico relacionado com as infeções, pode traduzir-se num aumento da demora média da hospitalização, no aumento da utilização de antibióticos, no recurso a…
(more)
▼ O custo económico relacionado com as infeções, pode traduzir-se num aumento da demora média da hospitalização, no aumento da utilização de antibióticos, no recurso a mais estudos laboratoriais e outros meios de diagnóstico para além dos custos intangíveis e sociais. Neste estudo pretendeu-se avaliar o custo das infeções do local cirúrgico (ILC) ocorridas durante o ano de 2009 nos serviços de cirurgia geral do Hospital Geral de Santo António, unidade do Centro Hospitalar do Porto (CHP). A população estudada correspondeu ao número total de registos de procedimentos cirúrgicos efetuados, à data da alta do doente, que foram enviados à comissão de controlo de infeção, num total de 1280 episódios, que correspondem a 44,2% da totalidade dos doentes saídos dos serviços cirúrgicos. Realizou-se um estudo retrospetivo de tipo caso-controlo em que as questões que orientaram a investigação e sobre as quais se apoiam os resultados foram:
Quantos casos de ILC foram identificados?
Quais os custos associados em termos de consumo de antibióticos e tempo de internamento nos casos e controlos?
Qual o custo das ILC nos serviços de cirurgia geral do CHP?
Foram identificados 37 casos (doentes com ILC), que correspondem a uma percentagem de 2,9% de um total de 1280 doentes. Os controlos, em igual número foram extraídos da restante população, recorrendo ao emparelhamento por código do procedimento cirúrgico, classificação American Society of Anaesthesiologists (ASA) e classe etária. A média de idade no grupo dos casos foi 63 anos, no grupo dos controlos 62 anos e na população 56 anos de idade. Das 37 ILC identificadas 25 foram classificadas como superficiais o que corresponde a 67,6%. O tipo de cirurgia urgente verificou-se em 57% dos casos. A ferida cirúrgica foi classificada como contaminada e/ou conspurcada em 54% dos casos.
No presente estudo foi analisado o consumo de antibióticos com base na informação disponibilizada pelo Serviço de Sistemas de Informação e o cálculo final do custo foi efetuado pelo tempo de internamento em dias (desde o dia da intervenção cirúrgica até ao dia da alta) em que o valor de custo/dia foi disponibilizado pelo Gabinete de Informação para a Gestão. O cálculo foi efetuado para cada doente no respetivo serviço, sendo posteriormente, calculado o valor médio para os custos associados às ILC em estudo. O resultado final foi de 3 323€.
O conhecimento dos custos com o tratamento das infeções permite aos decisores pesar o custo/benefício e justificar os investimentos no âmbito da prevenção especialmente quando há estudos que demonstram que uma percentagem destas infeções é evitável
The economic costs related to infections, can increase the average length of hospital stay, antibiotics use and other drugs, the use of more laboratory and other diagnostic methods in addition to the social and intangible costs. This study aimed to make a cost analyses, attributable to surgical site infections (SSI) during the year 2009 in general surgery services at the Hospital Geral de Santo Antonio, a unit of the Centro…
Advisors/Committee Members: Vasconcelos, Carlos, Polónia, Antonio.
Subjects/Keywords: Infecção do local cirúrgico; Vigilância epidemiológica; Controlo de Infeçãocão; Estudo de custos; Surgical site infection; Surveillance; Infection control; Cost analysis
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APA (6th Edition):
Aires, E. (2011). Avaliação de custos associados à infeção do local cirúrgico nos serviços de cirurgia geral dos Hospital geral Santo António. (Thesis). RCAAP. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:repositorio.ucp.pt:10400.14/8820
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Aires, Ernestina. “Avaliação de custos associados à infeção do local cirúrgico nos serviços de cirurgia geral dos Hospital geral Santo António.” 2011. Thesis, RCAAP. Accessed April 18, 2021.
http://www.rcaap.pt/detail.jsp?id=oai:repositorio.ucp.pt:10400.14/8820.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Aires, Ernestina. “Avaliação de custos associados à infeção do local cirúrgico nos serviços de cirurgia geral dos Hospital geral Santo António.” 2011. Web. 18 Apr 2021.
Vancouver:
Aires E. Avaliação de custos associados à infeção do local cirúrgico nos serviços de cirurgia geral dos Hospital geral Santo António. [Internet] [Thesis]. RCAAP; 2011. [cited 2021 Apr 18].
Available from: http://www.rcaap.pt/detail.jsp?id=oai:repositorio.ucp.pt:10400.14/8820.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Aires E. Avaliação de custos associados à infeção do local cirúrgico nos serviços de cirurgia geral dos Hospital geral Santo António. [Thesis]. RCAAP; 2011. Available from: http://www.rcaap.pt/detail.jsp?id=oai:repositorio.ucp.pt:10400.14/8820
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
17.
Mulder, Tessa|info:eu-repo/dai/nl/413967840.
Prevention of severe infectious complications after colorectal surgery.
Degree: 2019, University Utrecht
URL: https://dspace.library.uu.nl/handle/1874/383687
;
URN:NBN:NL:UI:10-1874-383687
;
urn:isbn:9789402816211
;
URN:NBN:NL:UI:10-1874-383687
;
https://dspace.library.uu.nl/handle/1874/383687
► In the Netherlands, one in ten patients who undergo colorectal surgery develops a wound infection. These infections have important consequences: they cause pain, extend the…
(more)
▼ In the Netherlands, one in ten patients who undergo colorectal surgery develops a wound
infection. These infections have important consequences: they cause pain, extend the length of hospital stay and increase the risk of another
surgical intervention. Despite preventative measures, the risk of
infection remains high. This thesis aimed to improve
infection control for colorectal surgery using two approaches. First, we investigated if we could enhance the efficiency of
infection surveillance. We found that 98.5% of infections were detected by an algorithm that uses information from the medical records. Consequently, the time spent on detecting infections was strongly reduced. Secondly, we studied if infections could be prevented with preventative oral antibiotics that are taken before surgery, also called oral antibiotic prophylaxis (OAP). We first studied the impact of OAP in one hospital were OAP was implemented and found that OAP reduced severe wound infections by 42%. We also investigated if OAP is safe by analyzing the blood of patients who took OAP. The antibiotics are thought not to be absorbed by the gut, which strongly lowers the risk of pharmacological side effects. We did not find any traces of antibiotics in the blood, which confirmed our hypothesis. Consequently, we conducted a placebo-controlled trial in six Dutch hospitals to confirm the efficacy of OAP and to thoroughly study the risk of side effects. The trial was prematurely ended as other studies provided evidence for beneficial effect of OAP and it was no longer considered ethical to treat patients with a placebo.
Advisors/Committee Members: Kluijtmans, Jan, Bonten, Marc, ten Berg, MJ.
Subjects/Keywords: Surgical site infection; Colorectal surgery; Infection prevention
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APA (6th Edition):
Mulder, T. (2019). Prevention of severe infectious complications after colorectal surgery. (Doctoral Dissertation). University Utrecht. Retrieved from https://dspace.library.uu.nl/handle/1874/383687 ; URN:NBN:NL:UI:10-1874-383687 ; urn:isbn:9789402816211 ; URN:NBN:NL:UI:10-1874-383687 ; https://dspace.library.uu.nl/handle/1874/383687
Chicago Manual of Style (16th Edition):
Mulder, Tessa|info:eu-repo/dai/nl/413967840. “Prevention of severe infectious complications after colorectal surgery.” 2019. Doctoral Dissertation, University Utrecht. Accessed April 18, 2021.
https://dspace.library.uu.nl/handle/1874/383687 ; URN:NBN:NL:UI:10-1874-383687 ; urn:isbn:9789402816211 ; URN:NBN:NL:UI:10-1874-383687 ; https://dspace.library.uu.nl/handle/1874/383687.
MLA Handbook (7th Edition):
Mulder, Tessa|info:eu-repo/dai/nl/413967840. “Prevention of severe infectious complications after colorectal surgery.” 2019. Web. 18 Apr 2021.
Vancouver:
Mulder T. Prevention of severe infectious complications after colorectal surgery. [Internet] [Doctoral dissertation]. University Utrecht; 2019. [cited 2021 Apr 18].
Available from: https://dspace.library.uu.nl/handle/1874/383687 ; URN:NBN:NL:UI:10-1874-383687 ; urn:isbn:9789402816211 ; URN:NBN:NL:UI:10-1874-383687 ; https://dspace.library.uu.nl/handle/1874/383687.
Council of Science Editors:
Mulder T. Prevention of severe infectious complications after colorectal surgery. [Doctoral Dissertation]. University Utrecht; 2019. Available from: https://dspace.library.uu.nl/handle/1874/383687 ; URN:NBN:NL:UI:10-1874-383687 ; urn:isbn:9789402816211 ; URN:NBN:NL:UI:10-1874-383687 ; https://dspace.library.uu.nl/handle/1874/383687
18.
船原, まどか.
Efficacy of topical antibiotic administration on the inhibition of perioperative oral bacterial growth in oral cancer patients: a preliminary study : 抗菌薬局所投与による口腔がん術後患者の口腔内細菌数増殖抑制効果：予備的研究.
Degree: 博士(歯学), 2016, Nagasaki University / 長崎大学
URL: http://hdl.handle.net/10069/36834
► Parenteral antibiotic prophylaxis is the current standard of therapy in cleancontaminated oral cancer surgery. Nevertheless, the incidence of surgical site infection (SSI) in oral oncological…
(more)
▼ Parenteral antibiotic prophylaxis is the current standard of therapy in cleancontaminated oral cancer surgery. Nevertheless, the incidence of surgical site
infection (SSI) in oral oncological surgery is relatively high, especially in major
surgery with reconstruction and tracheotomy. The aims of this study were to investigate the perioperative condition related to microorganisms in the oral cavity and to examine the efficacy of the topical administration of tetracycline in reducing
the number of bacteria in the oropharyngeal fluid during intubation. The number of
oral bacteria was measured during intubation in patients undergoing major oral cancer surgery. The efficacy of the topical administration of tetracycline or povidone iodine gel in reducing the bacteria was then investigated. Bacteria in the oropharyngeal fluid grew from 106 CFU/ml to 108 CFU/ml during the 3 h after intubation (CFU, colony-forming units). When tetracycline was applied to the dorsum of the tongue, oral bacteria decreased immediately to 105 CFU/ml, and the number of bacteria in the oropharyngeal fluid was maintained below 107 CFU/ml for 7 h. The concentration of tetracycline in the oropharyngeal fluid was extremely high for several hours after topical administration. The topical administration of tetracycline could reduce oral bacteria in patients undergoing clean-contaminated oral cancer surgery. This method is expected to be effective in the prevention of SSI.
Subjects/Keywords: surgical site infection; topical administration of antibiotics; oral cancer surgery; oral care; oral bacteria
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APA (6th Edition):
船原, . (2016). Efficacy of topical antibiotic administration on the inhibition of perioperative oral bacterial growth in oral cancer patients: a preliminary study : 抗菌薬局所投与による口腔がん術後患者の口腔内細菌数増殖抑制効果：予備的研究. (Thesis). Nagasaki University / 長崎大学. Retrieved from http://hdl.handle.net/10069/36834
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
船原, まどか. “Efficacy of topical antibiotic administration on the inhibition of perioperative oral bacterial growth in oral cancer patients: a preliminary study : 抗菌薬局所投与による口腔がん術後患者の口腔内細菌数増殖抑制効果：予備的研究.” 2016. Thesis, Nagasaki University / 長崎大学. Accessed April 18, 2021.
http://hdl.handle.net/10069/36834.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
船原, まどか. “Efficacy of topical antibiotic administration on the inhibition of perioperative oral bacterial growth in oral cancer patients: a preliminary study : 抗菌薬局所投与による口腔がん術後患者の口腔内細菌数増殖抑制効果：予備的研究.” 2016. Web. 18 Apr 2021.
Vancouver:
船原 . Efficacy of topical antibiotic administration on the inhibition of perioperative oral bacterial growth in oral cancer patients: a preliminary study : 抗菌薬局所投与による口腔がん術後患者の口腔内細菌数増殖抑制効果：予備的研究. [Internet] [Thesis]. Nagasaki University / 長崎大学; 2016. [cited 2021 Apr 18].
Available from: http://hdl.handle.net/10069/36834.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
船原 . Efficacy of topical antibiotic administration on the inhibition of perioperative oral bacterial growth in oral cancer patients: a preliminary study : 抗菌薬局所投与による口腔がん術後患者の口腔内細菌数増殖抑制効果：予備的研究. [Thesis]. Nagasaki University / 長崎大学; 2016. Available from: http://hdl.handle.net/10069/36834
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Universidade Federal de Viçosa
19.
Daniel Pontes Braga.
Incidência e fatores de risco associados à infecção do sítio cirúrgico na clínica de cães e gatos do hospital veterinário da Universidade Federal de Viçosa.
Degree: 2008, Universidade Federal de Viçosa
URL: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=2242
► O objetivo deste estudo foi verificar a incidência de infecção do sítio cirúrgico na Clinica Cirúrgica de Cães e Gatos do Hospital Veterinário da Universidade…
(more)
▼ O objetivo deste estudo foi verificar a incidência de infecção do sítio cirúrgico na Clinica Cirúrgica de Cães e Gatos do Hospital Veterinário da Universidade Federal de Viçosa e a associação da ocorrência de infecção aos fatores de riscos já descritos. Objetivou-se ainda despertar o interesse para o problema, considerando que as infecções hospitalares muitas vezes passam despercebidas ou não são devidamente registradas, e consequentemente, propor medidas para sua prevenção e seu controle. Foi realizado um estudo de coorte concorrente prospectivo. O método de vigilância epidemiológica empregado foi baseado na busca ativa de “pistas” que indicassem a ocorrência de ISC.Todos os pacientes submetidos a procedimentos cirúrgicos, no esquema de ambulatório dia no período proposto foram analisados através de seus prontuários clínicos, fichas cirúrgicas e anestésicas, além de colheita de informações com veterinários, cuidadores e proprietários. Foram analisados 307 pacientes (356 procedimentos) cirúrgicos, no período de 11 de maio a 11 de novembro de 2007. Os possíveis casos foram avaliados pelo pesquisador e veterinários observadores sendo identificados 34 casos de ISC entre os pacientes submetidos à cirurgia no período proposto. A análise dos dados e documentação hospitalar propiciou um levantamento preciso de todos os procedimentos realizados no período e também foi verificada a dinâmica de preenchimento da documentação hospitalar. Verificou-se a inexistência de uma padronização dos registros realizados nos prontuários e da antibioticoprofilaxia cirúrgica prescrita. Encontrou-se uma incidência global de ISC de 9,5% sendo compatível com as taxas descritas na literatura consultada e uma incidência de 10,4 % em cirurgias limpas e 7,4% em potencialmente contaminadas, sendo estes índices maiores que os observados na literatura estudada. Não foi verificado a associação entre ISC, tempo de duração da cirurgia, cirurgias ortopédicas e não ortopédicas com ou sem utilização de próteses. Entretanto, registrou-se a associação entre o registro de interferência do paciente na ferida cirúrgica e a ocorrência de ISC. Verificou-se como possíveis fatores de risco para ISC: a falta de um processo de vigilância das infecções hospitalares, emprego não padronizado de antibioticoprofilaxia, falta de normas e rotinas referentes à prevenção e controle das infecções hospitalares, falta de treinamento e orientação adequada dos profissionais e falta do cumprimento da legislação vigente. Portanto, baseado nos dados apurados e observações realizadas durante o estudo, verificou-se a necessidade de providências no controle e prevenção das ISC.
The objective of this study was to verify the incidence of infection in the surgical site at the Dog and Cat Surgery Clinic at the Veterinary Hospital of the Universidade Federal de Viçosa (UFV) and the association of occurrence of infection with the risk factors previously described. Another aim was to attract interest to this issue, since hospital infections very often remain unnoticed or are not…
Advisors/Committee Members: Luiz Gonzaga Pompermayer, Maria Aparecida Scatamburlo Moreira, José Antonio Viana, Andrea Pacheco Batista Borges, Ricardo Junqueira Del Carlo, Paula Dias Bevilacqua, Anna Maria de Oliveira Salimena.
Subjects/Keywords: Infecção; Pequenos animais; Sítio cirúrgico; CLINICA E CIRURGIA ANIMAL; Infection; Surgical site; Small animals
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APA (6th Edition):
Braga, D. P. (2008). Incidência e fatores de risco associados à infecção do sítio cirúrgico na clínica de cães e gatos do hospital veterinário da Universidade Federal de Viçosa. (Thesis). Universidade Federal de Viçosa. Retrieved from http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=2242
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Braga, Daniel Pontes. “Incidência e fatores de risco associados à infecção do sítio cirúrgico na clínica de cães e gatos do hospital veterinário da Universidade Federal de Viçosa.” 2008. Thesis, Universidade Federal de Viçosa. Accessed April 18, 2021.
http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=2242.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Braga, Daniel Pontes. “Incidência e fatores de risco associados à infecção do sítio cirúrgico na clínica de cães e gatos do hospital veterinário da Universidade Federal de Viçosa.” 2008. Web. 18 Apr 2021.
Vancouver:
Braga DP. Incidência e fatores de risco associados à infecção do sítio cirúrgico na clínica de cães e gatos do hospital veterinário da Universidade Federal de Viçosa. [Internet] [Thesis]. Universidade Federal de Viçosa; 2008. [cited 2021 Apr 18].
Available from: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=2242.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Braga DP. Incidência e fatores de risco associados à infecção do sítio cirúrgico na clínica de cães e gatos do hospital veterinário da Universidade Federal de Viçosa. [Thesis]. Universidade Federal de Viçosa; 2008. Available from: http://www.tede.ufv.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=2242
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
20.
Pinheiro, Paula Cristina Onofre.
Protocolo de prevenção de infeção do local cirúrgico.
Degree: 2018, Universidade de Évora
URL: https://www.rcaap.pt/detail.jsp?id=oai:dspace.uevora.pt:10174/23423
► O Estágio final, integrado no Curso de Mestrado em Enfermagem- Especialização em Enfermagem Médico-Cirúrgica: Pessoa em situação crítica permite o desenvolvimento de competências técnico-científicas, humanas…
(more)
▼ O Estágio final, integrado no Curso de Mestrado em Enfermagem- Especialização em Enfermagem Médico-Cirúrgica: Pessoa em situação crítica permite o desenvolvimento de competências técnico-científicas, humanas e relacionais, descritas neste relatório.
As infeções associadas aos cuidados de saúde representam, em todo o mundo, o evento adverso mais comum que coloca em causa a segurança do doente. A infeção do local cirúrgico afeta 1/3 dos doentes que foram submetidos a um procedimento cirúrgico. A sua prevenção é um processo complexo, que envolve uma série de medidas que devem integrar o período peri-operatório (OMS,016). Atualmente, assume-se como um desafio para todos os profissionais de saúde. Objetivos: Criar e implementar uma instrução de trabalho, com o intuito de uniformizar procedimentos que reduzam a incidência de infeção do local cirúrgico. Metodologia: Após a constatação da problemática, foi elaborada, discutida, apresentada e implementada uma instrução de trabalho, utilizando a metodologia de projeto. A mesma foi divulgada à equipa através de formação em serviço. Resultados: A criação dos documentos acima referidos, pretendem colmatar algumas lacunas identificadas na prevenção de ILC. No entanto, pelo seu carácter, não permite a obtenção de resultados imediatos. Conclusão: As instruções de trabalho pretendem vir a ser uma mais valia para o serviço, na prevenção de eventos adversos, nomeadamente infeção do local cirúrgico, melhorando a qualidade dos cuidados prestados; ABSTRACT:
Protocol to prevention of the
surgical site infection
The final stage, integrated in the Master Course in Nursing - Specialization in Medical-
Surgical Nursing: Person in critical situation allows the development of technical-scientific, human and relational skills, described in this report.
Infections associated with health care represent the most common adverse event in the world that puts patient safety at risk.
Infection of the
surgical site affects 1/3 of the patients who underwent a
surgical procedure. Its prevention is a complex process involving a series of measures that should be part of the perioperative period (WHO, 016). Currently, it is a challenge for all health professionals. Objectives: To create and implement a work instruction, in order to standardize procedures that reduce the incidence of
surgical site infection. Methodology: After the problem was established, a working instruction was elaborated, discussed, presented and implemented using the project methodology. It was disclosed to the team through in-service training. Results: The creation of the aforementioned documents, aim to fill some gaps identified in the prevention of ILC. However, by its character, it does not allow to obtain immediate results. Conclusion: The instructions of work are intended to be an added value for the service, in the prevention of adverse events, namely
infection of the
surgical site, improving the quality of care provided.
Advisors/Committee Members: Pedro, Adriano Dias.
Subjects/Keywords: Prevenção; Infeção do local cirúrgico; Instrução de trabalho; Prevention; Surgical site infection; Work instruction
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APA (6th Edition):
Pinheiro, P. C. O. (2018). Protocolo de prevenção de infeção do local cirúrgico. (Thesis). Universidade de Évora. Retrieved from https://www.rcaap.pt/detail.jsp?id=oai:dspace.uevora.pt:10174/23423
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Pinheiro, Paula Cristina Onofre. “Protocolo de prevenção de infeção do local cirúrgico.” 2018. Thesis, Universidade de Évora. Accessed April 18, 2021.
https://www.rcaap.pt/detail.jsp?id=oai:dspace.uevora.pt:10174/23423.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Pinheiro, Paula Cristina Onofre. “Protocolo de prevenção de infeção do local cirúrgico.” 2018. Web. 18 Apr 2021.
Vancouver:
Pinheiro PCO. Protocolo de prevenção de infeção do local cirúrgico. [Internet] [Thesis]. Universidade de Évora; 2018. [cited 2021 Apr 18].
Available from: https://www.rcaap.pt/detail.jsp?id=oai:dspace.uevora.pt:10174/23423.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Pinheiro PCO. Protocolo de prevenção de infeção do local cirúrgico. [Thesis]. Universidade de Évora; 2018. Available from: https://www.rcaap.pt/detail.jsp?id=oai:dspace.uevora.pt:10174/23423
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Iowa
21.
Merriman, Joseph Alan.
Secreted Staphylococcus aureus virulence factors and their role in chronic wound development and persistence.
Degree: PhD, Microbiology, 2015, University of Iowa
URL: https://ir.uiowa.edu/etd/1989
► Staphylococcus aureus is a gram-positive opportunistic pathogen responsible for more deaths every year than HIV/AIDS. Its formidable repertoire of virulence factors, ubiquitous nature, and…
(more)
▼ Staphylococcus aureus is a gram-positive opportunistic pathogen responsible for more deaths every year than HIV/AIDS. Its formidable repertoire of virulence factors, ubiquitous nature, and ability to acquire antibiotic resistance quickly allow S. aureus to colonize and persist in nearly any body
site if given the opportunity. S. aureus is the leading cause of many common and severe skin diseases, i.e. atopic dermatitis and
surgical site infections, which can result in significant morbidity and mortality due to lack of available treatments and chronic non-healing nature of each
infection. The human body is capable of producing many antimicrobial factors, such as defensins in the epidermis, in conjunction with providing a seamless barrier to many environmental threats, i.e. the skin, yet when given the opportunity, S. aureus can overtake these innate defenses, colonize, and cause disease. Despite S. aureus being a prominent organism in skin infections, little has been done to identify critical factors of S. aureus to cause skin infections. This document demonstrates the capacity of specific S. aureus virulence factors, superantigens and cytotoxins, to alter re-epithelialization and wound healing, as indicated by altered keratinocyte migration and proliferation. In an attempt to harness natural occurring host defenses, we have also identified and generated novel antimicrobial peptides capable of ablating toxin production independent of bacterial growth inhibition. Evidence presented should convince the reader that S. aureus exotoxin production is critical in perpetuating chronic wounds through local keratinocyte interaction. This suggests targeting production of these toxins to prevent cell toxicity and inflammatory responses, could allow the host to repair damaged tissue effectively.
Advisors/Committee Members: Schlievert, Patrick M., 1949- (supervisor).
Subjects/Keywords: publicabstract; atopic dermatitis; S. aureus; secreted factors; surgical site infection; therapeutic; Microbiology
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APA (6th Edition):
Merriman, J. A. (2015). Secreted Staphylococcus aureus virulence factors and their role in chronic wound development and persistence. (Doctoral Dissertation). University of Iowa. Retrieved from https://ir.uiowa.edu/etd/1989
Chicago Manual of Style (16th Edition):
Merriman, Joseph Alan. “Secreted Staphylococcus aureus virulence factors and their role in chronic wound development and persistence.” 2015. Doctoral Dissertation, University of Iowa. Accessed April 18, 2021.
https://ir.uiowa.edu/etd/1989.
MLA Handbook (7th Edition):
Merriman, Joseph Alan. “Secreted Staphylococcus aureus virulence factors and their role in chronic wound development and persistence.” 2015. Web. 18 Apr 2021.
Vancouver:
Merriman JA. Secreted Staphylococcus aureus virulence factors and their role in chronic wound development and persistence. [Internet] [Doctoral dissertation]. University of Iowa; 2015. [cited 2021 Apr 18].
Available from: https://ir.uiowa.edu/etd/1989.
Council of Science Editors:
Merriman JA. Secreted Staphylococcus aureus virulence factors and their role in chronic wound development and persistence. [Doctoral Dissertation]. University of Iowa; 2015. Available from: https://ir.uiowa.edu/etd/1989
University of Guelph
22.
Anderson, Maureen E. C.
Video Observation of Infection Control Practices in Veterinary Clinics and a Petting Zoo, with Emphasis on Hand Hygiene and Interventions to Improve Hand Hygiene Compliance.
Degree: PhD, Department of Pathobiology, 2013, University of Guelph
URL: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/6648
► This thesis is an investigation of the use of various infection control practices, including hand hygiene, in companion animal veterinary clinics and a public petting…
(more)
▼ This thesis is an investigation of the use of various
infection control practices, including hand hygiene, in companion animal veterinary clinics and a public petting zoo. Video observation of petting zoo visitors found overall hand hygiene compliance was 58% (340/583). Improved signage with offering hand sanitizer (odds ratio (OR) 3.38, p<0.001) and verbal hand hygiene reminders (OR 1.73, p=0.037) had a significant positive association with compliance. Video observation of preoperative preparation practices in ten veterinary clinics found contact times with preparatory solutions were often shorter than recommended: 10-462s for patients and 7-529s for surgeons using soap and water. Practices that did not conform to guidelines available in major companion animal
surgical textbooks were commonly observed. A survey of veterinary staff found that over 80% of respondents ranked hand hygiene as of high importance in all clinical situations queried. The most frequently reported reason for not performing hand hygiene was forgetting to do so (40%, 141/353). Video observation of various
infection control practices in 47 veterinary clinics found that poor sharps handling practices were common, yet only one needlestick injury was observed. Exam tables were cleaned following 76% (2015/2646) of appointments, and contact time with spray used to do so ranged from 0-4611s (mean 39s, median 9s). Appropriate personal protective clothing was worn for 72% (3518/4903) of staff-animal contacts. Video observation of hand hygiene practices in 38 veterinary clinics found overall hand hygiene compliance was 14% (1473/10894). Soap and water was used for 87% (1182/1353) of observed hand hygiene attempts with a mean contact time of 4s (median 2s, range 1-49s). A hand hygiene poster campaign had no significant effect on compliance. There is clearly room for improvement with regard to many frequently used
infection control measures in veterinary clinics in Ontario. Use of active interventions to improve practices such as hand hygiene should be investigated in clinics, as such measures have been effective in other settings. The video monitoring system used in this research may be a useful tool for conducting these and similar studies in the future. A better
infection control culture needs to be established in veterinary medicine. Accompanying data files are located at: http://hdl.handle.net/10864/10445
Advisors/Committee Members: Weese, J. Scott (advisor).
Subjects/Keywords: hand hygiene; infection control; veterinary; companion animal; petting zoo; video observation; surgical site antisepsis
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APA (6th Edition):
Anderson, M. E. C. (2013). Video Observation of Infection Control Practices in Veterinary Clinics and a Petting Zoo, with Emphasis on Hand Hygiene and Interventions to Improve Hand Hygiene Compliance. (Doctoral Dissertation). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/6648
Chicago Manual of Style (16th Edition):
Anderson, Maureen E C. “Video Observation of Infection Control Practices in Veterinary Clinics and a Petting Zoo, with Emphasis on Hand Hygiene and Interventions to Improve Hand Hygiene Compliance.” 2013. Doctoral Dissertation, University of Guelph. Accessed April 18, 2021.
https://atrium.lib.uoguelph.ca/xmlui/handle/10214/6648.
MLA Handbook (7th Edition):
Anderson, Maureen E C. “Video Observation of Infection Control Practices in Veterinary Clinics and a Petting Zoo, with Emphasis on Hand Hygiene and Interventions to Improve Hand Hygiene Compliance.” 2013. Web. 18 Apr 2021.
Vancouver:
Anderson MEC. Video Observation of Infection Control Practices in Veterinary Clinics and a Petting Zoo, with Emphasis on Hand Hygiene and Interventions to Improve Hand Hygiene Compliance. [Internet] [Doctoral dissertation]. University of Guelph; 2013. [cited 2021 Apr 18].
Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/6648.
Council of Science Editors:
Anderson MEC. Video Observation of Infection Control Practices in Veterinary Clinics and a Petting Zoo, with Emphasis on Hand Hygiene and Interventions to Improve Hand Hygiene Compliance. [Doctoral Dissertation]. University of Guelph; 2013. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/6648
Freie Universität Berlin
23.
Hoffmann, Maria.
Influence of appendectomy technique on postoperative outcome.
Degree: 2012, Freie Universität Berlin
URL: https://refubium.fu-berlin.de/handle/fub188/10875
► Purpose Appendectomy is one of the most frequent surgeries performed. The role of laparoscopy in the treatment of appendicitis remains controversial concerning the complication rate.…
(more)
▼ Purpose Appendectomy is one of the most frequent surgeries performed. The role
of laparoscopy in the treatment of appendicitis remains controversial
concerning the complication rate. The aim of this retrospective cohort study
was to compare open and laparoscopic appendectomy for postoperative outcome.
We also compared laparoscopic appendectomy using endoloops versus linear
stapling to secure the base of the appendix. Methods All patients undergoing
appendectomy between January 1, 2007 and May 31, 2010 were included in the
study. Perioperative data and data on postoperative complications were
collected from patient files. A questionnaire was used in order to assess
complications after discharge. Main outcome parameters were SSI and IAA. Open
appendectomy (OAG) and laparoscopic appendectomy (LAG) were compared with
univariate and multivariate analyses for the outcome parameters. Results 430
Patients were included in the study. SSI (all: 10.6%, OAG: 11.7%, LAG: 7.5%,
p=0.293) and IAA (all: 2.8%, OAG: 2.4%, LAG: 3.8%, p=0.506) were not
significantly different between OAG and LAG. Risk factors for SSI were age
(p=0.003), body mass index (p=0.017), ASA score (p=0.001), the intraoperative
grade of inflammation (p=0.004) and the histological grade of inflammation
(p=0.015). The only risk factor for IAA was the intraoperative grade of
inflammation (p=0.028). ASA score (odds ratio: 1.992, p=0.032) and the
intraoperative grade of inflammation (odds ratio: 1.573, p=0.006) remained
significant in the multivariate analysis for SSI. Conclusion A higher ASA
score correlates with SSI. A higher grade of intraoperative inflammation
correlates with SSI and IAA. Laparoscopy has no impact on SSI and IAA in
appendectomy. Laparoscopic appendectomy was associated with a shorter hospital
length of stay. In laparoscopic appendectomy there were no significant
differences between the use of endoloops and linear stapling devices regarding
postoperative outcome.
Advisors/Committee Members: [email protected] (contact), w (gender), Prof. Dr. med. J.-P. Ritz (firstReferee), Priv.-Doz. Dr. med. A. Kroesen (furtherReferee), Priv.-Doz. Dr. med. O. Guckelberger (furtherReferee).
Subjects/Keywords: appendectomy; surgical site infection; intraabdominal abscess; 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit
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APA ·
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APA (6th Edition):
Hoffmann, M. (2012). Influence of appendectomy technique on postoperative outcome. (Thesis). Freie Universität Berlin. Retrieved from https://refubium.fu-berlin.de/handle/fub188/10875
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Hoffmann, Maria. “Influence of appendectomy technique on postoperative outcome.” 2012. Thesis, Freie Universität Berlin. Accessed April 18, 2021.
https://refubium.fu-berlin.de/handle/fub188/10875.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Hoffmann, Maria. “Influence of appendectomy technique on postoperative outcome.” 2012. Web. 18 Apr 2021.
Vancouver:
Hoffmann M. Influence of appendectomy technique on postoperative outcome. [Internet] [Thesis]. Freie Universität Berlin; 2012. [cited 2021 Apr 18].
Available from: https://refubium.fu-berlin.de/handle/fub188/10875.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Hoffmann M. Influence of appendectomy technique on postoperative outcome. [Thesis]. Freie Universität Berlin; 2012. Available from: https://refubium.fu-berlin.de/handle/fub188/10875
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
24.
Gislaine Cristhina Bellusse.
Incidência de infecção de sítio cirúrgico em neurocirurgia.
Degree: 2013, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/22/22132/tde-14012014-112321/
► A infecção de sítio cirúrgico (ISC) é uma complicação frequente que pode acometer o paciente submetido ao procedimento anestésico cirúrgico. A importância dessa problemática está…
(more)
▼ A infecção de sítio cirúrgico (ISC) é uma complicação frequente que pode acometer o paciente submetido ao procedimento anestésico cirúrgico. A importância dessa problemática está no aumento da morbidade, mortalidade e dos custos hospitalares, e ainda, em relação ao paciente, pelo sofrimento emocional e físico, bem como o prolongamento do período de afastamento de suas atividades profissionais e do convívio social. A presente investigação teve como objetivo geral analisar a incidência de infecção de sítio cirúrgico em pacientes submetidos à neurocirurgia eletiva e limpa em hospital privado filantrópico, nível terciário, do interior do Estado de São Paulo. Para tal, realizou-se estudo com delineamento de pesquisa não experimental, tipo descritivo e prospectivo. A amostra foi composta por 85 sujeitos submetidos a neurocirurgias eletivas e limpas. Para a coleta de dados utilizou-se instrumento validado por estudioso da temática, esse procedimento
ocorreu durante o acompanhamento do paciente no perioperatório (pré, intra e pós-operatório) e, após a alta, no trigésimo dia após o procedimento cirúrgico, sendo agendado o retorno do paciente na sala de curativos do hospital onde a pesquisa foi conduzida. A coleta de dados teve a duração de onze meses (junho de 2012 a abril de 2013). A indicência de ISC foi de 9,4%, resultado superior ao preconizado na literatura para o tipo de procedimento cirúrgico estudado (cirurgia limpa). As variáveis estudadas relacionadas ao paciente foram idade, classificação ASA, Índice de Massa Coporal e presença de doenças crônicas. As variáveis investigadas relacionadas ao procedimento anestésico cirúrgico foram duração da anestesia, duração da cirurgia, uso de antibioticoprofilaxia e tempo total de internação. Em relação ao momento do diagnóstico, dos oito pacientes com ISC, cinco (62,5%) tiveram o diagnóstico durante o período em que permaneceram internados; dois (25%) após a alta por ocasião de
reinternação devido ISC e um (12,5%) no retorno agendado na sala de curativos. O estudo fornece subsídios para a reflexão dos profissionais de saúde sobre a incidência e os fatores predisponentes de ISC em neurocirurgia, os quais podem auxiliar na implementação de medidas de prevenção e controle para a problemática em razão dos efeitos deletérios acarretados no tocante aos custos e as repercussões familiares, sociais e financeiras ao paciente cirúrgico
The surgical site infection (SSI) is a common complication that can occur in patients undergoing the surgical anesthetic procedure. The importance of this problem is the increasing of morbidity, mortality and hospital costs, and also in relation to patients, the emotional and physical distress, as well as the extension of the period of absence from their professional and social life. This study aimed to analyze the incidence of surgical site infection in patients undergoing clean elective neurosurgery in a private philanthropic
hospital, tertiary level, in the state of São Paulo. For this,…
Advisors/Committee Members: Cristina Maria Galvao, Denise de Andrade, Vanessa de Brito Poveda.
Subjects/Keywords: Enfermagem Perioperatória; Incidência; Infecção de sítio cirúrgico; Neurocirurgia; Incidence; Neurosurgery; Perioperative Nursing; Surgical site infection
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APA (6th Edition):
Bellusse, G. C. (2013). Incidência de infecção de sítio cirúrgico em neurocirurgia. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/22/22132/tde-14012014-112321/
Chicago Manual of Style (16th Edition):
Bellusse, Gislaine Cristhina. “Incidência de infecção de sítio cirúrgico em neurocirurgia.” 2013. Masters Thesis, University of São Paulo. Accessed April 18, 2021.
http://www.teses.usp.br/teses/disponiveis/22/22132/tde-14012014-112321/.
MLA Handbook (7th Edition):
Bellusse, Gislaine Cristhina. “Incidência de infecção de sítio cirúrgico em neurocirurgia.” 2013. Web. 18 Apr 2021.
Vancouver:
Bellusse GC. Incidência de infecção de sítio cirúrgico em neurocirurgia. [Internet] [Masters thesis]. University of São Paulo; 2013. [cited 2021 Apr 18].
Available from: http://www.teses.usp.br/teses/disponiveis/22/22132/tde-14012014-112321/.
Council of Science Editors:
Bellusse GC. Incidência de infecção de sítio cirúrgico em neurocirurgia. [Masters Thesis]. University of São Paulo; 2013. Available from: http://www.teses.usp.br/teses/disponiveis/22/22132/tde-14012014-112321/
25.
Barros, Cláudia Silva Matinho.
Custos atribuídos às infecções de sítio cirúrgico em um Hospital Universitário em Salvador-Bahia.
Degree: 2016, Brazil
URL: https://www.arca.fiocruz.br/handle/icict/14243
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Made available in DSpace on 2016-05-11T13:53:53Z (GMT). No. of bitstreams: 1 Claudia Silva Marinho Antunes Barros Custos... 2016.pdf: 2575504 bytes, checksum: 2b64af2892aa58d02c2b0684383b6826 (MD5) Previous issue date: 2016
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
INTRODUÇÃO: As Infecções de Sítio Cirúrgico (ISCs) são as complicações mais freqüentes que ocorrem nos pacientes após as cirurgias e são responsáveis pela
elevação da morbidade, mortalidade e dos custos hospitalares. OBJETIVO: O objetivo deste estudo foi estimar o custo direto adicional associado às ISCs ocorridas no período de 2011 a 2013 em um Hospital Universitário de Salvador, Bahia. Para tanto buscou-se caracterizar a população de pacientes acometidos por ISC, segundo os aspectos sócio-demográficas, condições clínicas e cirurgias realizadas, realizar uma revisão integrativa atualizada da literatura mundial sobre o custo dessas infecções e analisar os custos associados aos cuidados à saúde dos pacientes cirúrgicos segundo presença de ISC. METODOLOGIA: Trata-se se um estudo epidemiológico do tipo caso-controle pareado, realizado com informações dos registros hospitalares dos pacientes. Foram incluídos como população do estudo todos os casos de ISCs em cirurgias eletivas e limpas. Os controles foram pareados por idade, sexo e tipo de cirurgia realizada respeitando o princípio da similaridade. As proporções foram comparadas por meio
dos testes 2 e exato de Fisher quando adequados com nível de 5% de significância estatística. Para estimar as diferenças das médias de custos utilizou-se o modelo de regressão linear. RESULTADOS: No total foram selecionados 259 pacientes. Os casos de ISC ocorreram predominantemente em mulheres, com idade entre 61 a 75 anos. Os principais fatores atribuídos aos custos com as ISCs foram o uso de antibióticos para o seu tratamento, a internação em Unidade de Terapia Intensiva, a realização de exames e reabordagens cirúrgicas. No geral, o custo médio hospitalar em pacientes com ISC foi aproximadamente o dobro do valor aferido daqueles não infectados. CONCLUSÕES: Foi evidenciado neste estudo a necessidade de reforçar o desenvolvimento constante de ações preventivas e de controle das ISCs a fim de garantir a segurança na assistência prestada aos pacientes cirúrgicos e conseqüentemente a redução dos custos atribuídos a essa complicação para o hospitais e sistema de saúde.
INTRODUCTION:
The Surgical Site Infections (SSI) are the most frequent complications occurring in patients after surgery and…
Advisors/Committee Members: Moreira Júnior, Edson Duarte, Machado, Carolina de Souza, Aragão, Erika Santos de, Reis, Mitermayer Galvão dos, Almeida, Maria da Conceição Chagas de.
Subjects/Keywords: Infecção de sítio cirúrgico; Custo; Custo em saúde; Cirurgia; Surgical site infection; Cost; Health cost
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APA (6th Edition):
Barros, C. S. M. (2016). Custos atribuídos às infecções de sítio cirúrgico em um Hospital Universitário em Salvador-Bahia. (Doctoral Dissertation). Brazil. Retrieved from https://www.arca.fiocruz.br/handle/icict/14243
Chicago Manual of Style (16th Edition):
Barros, Cláudia Silva Matinho. “Custos atribuídos às infecções de sítio cirúrgico em um Hospital Universitário em Salvador-Bahia.” 2016. Doctoral Dissertation, Brazil. Accessed April 18, 2021.
https://www.arca.fiocruz.br/handle/icict/14243.
MLA Handbook (7th Edition):
Barros, Cláudia Silva Matinho. “Custos atribuídos às infecções de sítio cirúrgico em um Hospital Universitário em Salvador-Bahia.” 2016. Web. 18 Apr 2021.
Vancouver:
Barros CSM. Custos atribuídos às infecções de sítio cirúrgico em um Hospital Universitário em Salvador-Bahia. [Internet] [Doctoral dissertation]. Brazil; 2016. [cited 2021 Apr 18].
Available from: https://www.arca.fiocruz.br/handle/icict/14243.
Council of Science Editors:
Barros CSM. Custos atribuídos às infecções de sítio cirúrgico em um Hospital Universitário em Salvador-Bahia. [Doctoral Dissertation]. Brazil; 2016. Available from: https://www.arca.fiocruz.br/handle/icict/14243
26.
Julio Cesar Ribeiro.
Efeito da hipotermia sobre a incidência de infeção de sítio cirúrgico em cirurgias abdominais: estudo de coorte.
Degree: 2018, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/22/22132/tde-24042018-194002/
► A infecção de sítio cirúrgico (ISC) é uma complicação frequente que pode acometer o paciente submetido ao procedimento anestésico cirúrgico, acarretando o aumento da morbidade,…
(more)
▼ A infecção de sítio cirúrgico (ISC) é uma complicação frequente que pode acometer o paciente submetido ao procedimento anestésico cirúrgico, acarretando o aumento da morbidade, mortalidade e dos custos hospitalares, bem como do sofrimento emocional e físico do paciente. Este estudo teve como objetivos estimar a incidência de ISC em pacientes submetidos à cirurgia abdominal, identificar as taxas de ISC segundo fatores relacionados ao paciente, ao procedimento anestésico cirúrgico e ao ambiente da sala cirúrgica, identificar os fatores de risco e de proteção, e identificar o efeito independente da hipotermia sobre a incidência de ISC. Para o alcance dos objetivos propostos, conduziu-se estudo de coorte com 484 pacientes submetidos à cirurgia abdominal. Para a coleta de dados elaborou-se instrumento, submetido à validação aparente e de conteúdo por cinco juízes. A coleta de dados foi realizada na unidade de internação ou na sala de recepção do centro
cirúrgico, no período intraoperatório, no período de internação e reinternação, e no retorno no 30° dia após a cirurgia. A hipotermia foi avaliada a partir de três mensurações distintas, a saber: 1 - temperatura Delta; 2 - número de vezes em que a temperatura do paciente foi <36,0°C; 3 - tempo de exposição, em minutos, em que o paciente esteve submetido a temperaturas <36,0°C. A incidência bruta de ISC foi de 20,25% (98 casos). A incidência de ISC apresentou maior magnitude nos participantes do sexo feminino (22,43%), nos pacientes na faixa etária de 60 anos e mais (27,22%), e com obesidade classe II (25,71%). As médias de duração da anestesia e da cirurgia foram maiores no grupo com ISC, a incidência de ISC apresentou maior magnitude naqueles pacientes submetidos a cirurgias de porte III (85,71%) e anestesia combinada (41,10%). A incidência de ISC apresentou maior magnitude naquele participante que no final da cirurgia estava exposto à temperatura da sala de operação
< 20°C (33,33%), e naqueles expostos à umidade do ar entre 45-55 kg/m3 (22,18%). Na mensuração 1 (modelo final), a hipotermia não apresentou relação causal com a ISC, e as variáveis classificação ASA, porte cirúrgico e tipo de anestesia permaneceram independentemente associadas à ISC. Na mensuração 2 (modelo final), identificou-se o efeito causal independente da hipotermia sobre a ISC, os pacientes que estiveram submetidos mais de cinco vezes a temperaturas <36,0°C apresentaram maior probabilidade (89%; RR=1,89) de desenvolverem ISC, as variáveis classificação ASA e tipo de anestesia mantiveram-se independentemente associadas à ISC. Na mensuração 3 (modelo final), também identificou-se o efeito causal independente da hipotermia sobre a ISC, os pacientes que estiveram submetidos a mais de 75 minutos a temperaturas <36,0°C apresentaram maior probabilidade (89%; RR=1,89) de desenvolverem ISC, as variáveis classificação ASA e tipo de anestesia permaneceram
independentemente associadas à ISC. A raquianestesia foi fator de proteção independente para ISC, nos três modelos finais. Os resultados evidenciados poderão…
Advisors/Committee Members: Cristina Maria Galvao, Silvia Rita Marin da Silva Canini, Isabel Cristina Martins de Freitas, Miyeko Hayashida, Vanessa de Brito Poveda.
Subjects/Keywords: Enfermagem Perioperatória; Hipotermia; Infecção de sítio cirúrgico; Hypothermia; Perioperative Nursing; Surgical site infection
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APA ·
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APA (6th Edition):
Ribeiro, J. C. (2018). Efeito da hipotermia sobre a incidência de infeção de sítio cirúrgico em cirurgias abdominais: estudo de coorte. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/22/22132/tde-24042018-194002/
Chicago Manual of Style (16th Edition):
Ribeiro, Julio Cesar. “Efeito da hipotermia sobre a incidência de infeção de sítio cirúrgico em cirurgias abdominais: estudo de coorte.” 2018. Doctoral Dissertation, University of São Paulo. Accessed April 18, 2021.
http://www.teses.usp.br/teses/disponiveis/22/22132/tde-24042018-194002/.
MLA Handbook (7th Edition):
Ribeiro, Julio Cesar. “Efeito da hipotermia sobre a incidência de infeção de sítio cirúrgico em cirurgias abdominais: estudo de coorte.” 2018. Web. 18 Apr 2021.
Vancouver:
Ribeiro JC. Efeito da hipotermia sobre a incidência de infeção de sítio cirúrgico em cirurgias abdominais: estudo de coorte. [Internet] [Doctoral dissertation]. University of São Paulo; 2018. [cited 2021 Apr 18].
Available from: http://www.teses.usp.br/teses/disponiveis/22/22132/tde-24042018-194002/.
Council of Science Editors:
Ribeiro JC. Efeito da hipotermia sobre a incidência de infeção de sítio cirúrgico em cirurgias abdominais: estudo de coorte. [Doctoral Dissertation]. University of São Paulo; 2018. Available from: http://www.teses.usp.br/teses/disponiveis/22/22132/tde-24042018-194002/
27.
Astrídia Marília de Souza Fontes.
Efetividade de intervenções na adequação da profilaxia antimicrobiana da infecção do sítio cirúrgico em um hospital universitário do Brasil.
Degree: 2010, Federal University of Uberlândia
URL: http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3155
► The surgical site infection is one of the main healthcare-associated infections (HAIs), the main surgical complication and the use of antimicrobials is part of a…
(more)
▼ The surgical site infection is one of the main healthcare-associated infections (HAIs), the main surgical complication and the use of antimicrobials is part of a set measures used in order to reduce this infection. There are well-conducted studies with general recommendations and specific standards for each type of surgery on surgical prophylaxis with antimicrobial. However, the inappropriate use of antimicrobials remains one of the major errors in medication administration in hospitals and prescription for far too long persists as one of the major flaws in the prophylaxis of surgical site infection (SSI). The purpose of this study is to know the effectiveness of interventions aimed at changing the conduct of surgeons regarding the correct indication and adequate time for maintenance of antimicrobial prophylaxis of SSI. It is a prospective study, before and after kind, conducted at Hospital das Clínicas de Uberlândia, an institution with a little more than 500-bed, linked to Universidade Federal de Uberlândia. There were two interventions: a prophylaxis with antimicrobial in surgery guide available, build up with the surgeon participation and Cefazolin liberation restriction, one of the more utilized antimicrobial with SSI prophylaxis purpose. Surgeries of the specialties trauma-orthopedic and general surgery and, the adaptation of antibiotic prophylaxis making reference to indication, antimicrobial prescribed and time of use. The study has been divided in three collection periods: baseline (period I), after the first intervention, elaboration and guide availableness (period II) and a third during the second intervention, Cefazolin restriction (period III). The indication of the use of prescribed antibiotic prophylaxis of SSI was considered adequate in the three collection periods. The antimicrobial choice has been convenient in the three periods of trauma-orthopedic however, in general surgery, the percents were 20%, 63,9% and 61,5% of the cases (p=0,011), respectively, in the three collection periods. The maintenance timing of the antimicrobial prophylaxis was considered adequate in 23,00% at the period I, in 46,15% at period II and 82,46% at period III (p<0,0001). The conclusion of this study is that educational interventions and mainly the administrative ones can increase of the use of antimicrobial prophylaxis in surgery.
A infecção do sítio cirúrgico (ISC) é uma das principais infecções relacionadas à assistência à saúde (IRAS) e a principal complicação das cirurgias. O uso de antimicrobiano faz parte de um conjunto de medidas usadas com a finalidade de diminuir IRAS. Estudos bem conduzidos sobre a profilaxia da ISC com antimicrobiano levaram a recomendações gerais e normas específicas para cada tipo de cirurgia. Entretanto, o uso inadequado do antimicrobiano permanece sendo um dos principais erros na administração de medicamentos nos hospitais e sua prescrição por tempo excessivamente longo persiste como uma das principais falhas na profilaxia da ISC. A proposta do presente estudo é conhecer a efetividade…
Advisors/Committee Members: Miguel Tanus Jorge, Gesmar Rodrigues Silva Segundo, Augusto Diogo Filho, Thaís Guimarães.
Subjects/Keywords: Antimicrobiano; Profilaxia cirúrgica; Infecção do sítio cirúrgico; CIENCIAS DA SAUDE; Infecção hospitalar; Antimicrobial; Surgical prophylaxis; Surgical site infection
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APA (6th Edition):
Fontes, A. M. d. S. (2010). Efetividade de intervenções na adequação da profilaxia antimicrobiana da infecção do sítio cirúrgico em um hospital universitário do Brasil. (Thesis). Federal University of Uberlândia. Retrieved from http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3155
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Fontes, Astrídia Marília de Souza. “Efetividade de intervenções na adequação da profilaxia antimicrobiana da infecção do sítio cirúrgico em um hospital universitário do Brasil.” 2010. Thesis, Federal University of Uberlândia. Accessed April 18, 2021.
http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3155.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Fontes, Astrídia Marília de Souza. “Efetividade de intervenções na adequação da profilaxia antimicrobiana da infecção do sítio cirúrgico em um hospital universitário do Brasil.” 2010. Web. 18 Apr 2021.
Vancouver:
Fontes AMdS. Efetividade de intervenções na adequação da profilaxia antimicrobiana da infecção do sítio cirúrgico em um hospital universitário do Brasil. [Internet] [Thesis]. Federal University of Uberlândia; 2010. [cited 2021 Apr 18].
Available from: http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3155.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Fontes AMdS. Efetividade de intervenções na adequação da profilaxia antimicrobiana da infecção do sítio cirúrgico em um hospital universitário do Brasil. [Thesis]. Federal University of Uberlândia; 2010. Available from: http://www.bdtd.ufu.br//tde_busca/arquivo.php?codArquivo=3155
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
28.
Stadñik, Claudio Marcel Berdún.
Adequação do horário de administração da antibioticoprofilaxia cirúrgica.
Degree: 2011, Brazil
URL: http://hdl.handle.net/10183/60756
► Introdução: A profilaxia antimicrobiana cirúrgica tem se demonstrado como uma das mais importantes medidas para redução das infecções de sítio cirúrgico. O momento da administração…
(more)
▼ Introdução: A profilaxia antimicrobiana cirúrgica tem se demonstrado como uma das mais importantes medidas para redução das infecções de sítio cirúrgico. O momento da administração dessa profilaxia é essencial para atingir concentrações terapêuticas nos tecidos durante o procedimento cirúrgico, condição freqüentemente não observada. O objetivo deste estudo foi caracterizar o lapso de tempo transcorrido entre a profilaxia antimicrobiana e o início da incisão cirúrgica. Métodos: Amostra de procedimentos cirúrgicos eletivos realizados em um hospital geral acompanhada mediante observação direta do momento de administração da antibioticoprofilaxia e da incisão. Resultados: Foram analisados 130 procedimentos. A maioria dos pacientes da amostra era do sexo feminino (64,6%). Em 60% dos procedimentos avaliados, os pacientes internaram no mesmo dia da cirurgia e o antimicrobiano mais utilizado foi cefazolina (91,5%). O antimicrobiano profilático foi
administrado com uma mediana de 8 minutos antes da incisão, sendo que em 18 (13,8%) procedimentos foi aplicado num tempo maior que 30 min e em 37 (28,5%), foi administrado após a incisão. Em apenas 13,8% a profilaxia foi administrada conforme o protocolo da instituição. As especialidades cujos procedimentos cirúrgicos apresentaram menor freqüência de adequação do horário de administração foram cirurgias plástica (4,5%), urologia (6,7) e vascular (9,1%). Conclusão: Apesar de consagrada, a administração da profilaxia em tempo adequado ainda permanece longe do ideal no nosso meio. As instituições devem adotar medidas eficazes para minimizar a inadequação desta medida.
Introduction: Antimicrobial surgical prophylaxis has been demonstrated as one of the most important steps to reduce surgical site infections. The timing of administration of prophylaxis is essential to achieve therapeutic concentrations in tissues during the surgical procedure, which is frequently not observed. The aim
of this study was to characterize the lapse of time between antimicrobial prophylaxis and beginning of surgical incision. Methods: A sample of elective surgeries performed in a general hospital accompanied by direct observation of the timing of administration of antibiotic prophylaxis and the incision. Results: We analyzed 130 procedures. Most of the patients were female (64.6%). In 60% of the procedures evaluated, patients hospitalized on the same day of surgery and antimicrobial more used was cefazolin (91.5%). The antibiotic prophylaxis was administered with a median of 8 minutes before incision, and in 18 (13.8%) procedures were applied to a time longer than 30 min and 37 (28.5%) was administered after the incision. In only 13.8% prophylaxis was administered according to institutional protocol. Whose specialty surgical procedures had lower rates of appropriateness of administration time were plastic surgery (4.5%), urology (6.7) and vascular (9.1%). Conclusion: Although
established, the administration of prophylaxis in a timely manner remains far from ideal in our midst. Institutions should adopt…
Advisors/Committee Members: Kuchenbecker, Ricardo de Souza.
Subjects/Keywords: Antibioticoprofilaxia; Complicações intraoperatórias; Surgical prophylaxis; Antibiotics; Surgical site infection
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APA ·
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Export
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Manager
APA (6th Edition):
Stadñik, C. M. B. (2011). Adequação do horário de administração da antibioticoprofilaxia cirúrgica. (Masters Thesis). Brazil. Retrieved from http://hdl.handle.net/10183/60756
Chicago Manual of Style (16th Edition):
Stadñik, Claudio Marcel Berdún. “Adequação do horário de administração da antibioticoprofilaxia cirúrgica.” 2011. Masters Thesis, Brazil. Accessed April 18, 2021.
http://hdl.handle.net/10183/60756.
MLA Handbook (7th Edition):
Stadñik, Claudio Marcel Berdún. “Adequação do horário de administração da antibioticoprofilaxia cirúrgica.” 2011. Web. 18 Apr 2021.
Vancouver:
Stadñik CMB. Adequação do horário de administração da antibioticoprofilaxia cirúrgica. [Internet] [Masters thesis]. Brazil; 2011. [cited 2021 Apr 18].
Available from: http://hdl.handle.net/10183/60756.
Council of Science Editors:
Stadñik CMB. Adequação do horário de administração da antibioticoprofilaxia cirúrgica. [Masters Thesis]. Brazil; 2011. Available from: http://hdl.handle.net/10183/60756
Vanderbilt University
29.
Fensterheim, Benjamin Ari.
Immunomodulatory Strategies for the Prevention of Nosocomial Infection.
Degree: PhD, Microbiology and Immunology, 2017, Vanderbilt University
URL: http://hdl.handle.net/1803/15507
► The growing incidence of nosocomial infection with antibiotic-resistant organisms requires novel approaches to decrease their incidence and severity. Predicting the infection risk of an individual…
(more)
▼ The growing incidence of
nosocomial infection with antibiotic-resistant organisms requires novel approaches to decrease their incidence and severity. Predicting the
infection risk of an individual host and restoring host immune function are two attractive strategies. Using in vivo and in vitro murine models of immune function and
infection, I determined that the magnitude of the cytokine response to lipopolysaccharide does not predict the host response to
infection. Moreover, I uncovered that the clinically available toll-like receptor 4 (TLR4) agonist monophosphoryl lipid A (MPLA) induces broad and persistent resistance to
nosocomial pathogens such as Staphylococcus aureus. This resistance arises through a sustained metabolic program in macrophages that supports improved pathogen clearance. MPLA initiates this program via mTOR activation, which spurs persistent glycolysis, mitochondrial biogenesis, increased malate shuttling, and increased ATP production. The enhanced energetic state supports augmented phagocytosis and constitutive monocyte/macrophage-targeted chemokine secretion, while pro-inflammatory cytokine and neutrophil-targeted chemokine secretion is suppressed. Rapamycin, which inhibited the development of the metabolic and functional phenotype, blocked MPLA-induced resistance to
infection. This work reveals that TLR4-induced metabolic reprogramming evolves to support the temporal goals of macrophages, and support the use of MPLA as an agent to facilitate broad-spectrum resistance to
infection in vulnerable patients.
Advisors/Committee Members: Mark Boothby, MD, PhD (committee member), Owen McGuinness, PhD (committee member), Edward Sherwood, MD, PhD (committee member), Luc Van Kaer, PhD (committee member), Amy Major, PhD (Committee Chair).
Subjects/Keywords: mitochondria; host defense; immunometabolism; hospital-acquired infection; nosocomial infection; macrophage
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APA (6th Edition):
Fensterheim, B. A. (2017). Immunomodulatory Strategies for the Prevention of Nosocomial Infection. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/15507
Chicago Manual of Style (16th Edition):
Fensterheim, Benjamin Ari. “Immunomodulatory Strategies for the Prevention of Nosocomial Infection.” 2017. Doctoral Dissertation, Vanderbilt University. Accessed April 18, 2021.
http://hdl.handle.net/1803/15507.
MLA Handbook (7th Edition):
Fensterheim, Benjamin Ari. “Immunomodulatory Strategies for the Prevention of Nosocomial Infection.” 2017. Web. 18 Apr 2021.
Vancouver:
Fensterheim BA. Immunomodulatory Strategies for the Prevention of Nosocomial Infection. [Internet] [Doctoral dissertation]. Vanderbilt University; 2017. [cited 2021 Apr 18].
Available from: http://hdl.handle.net/1803/15507.
Council of Science Editors:
Fensterheim BA. Immunomodulatory Strategies for the Prevention of Nosocomial Infection. [Doctoral Dissertation]. Vanderbilt University; 2017. Available from: http://hdl.handle.net/1803/15507
30.
Julio Cesar Ribeiro.
Análise da ocorrência e dos fatores predisponentes de infecção de sítio cirúrgico em pacientes sumetidos a cirurgias ortopédicas.
Degree: 2012, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/22/22132/tde-05112012-194139/
► A infecção de sítio cirúrgico é um dos principais problemas que pode acometer o paciente no perioperatório. Este tipo de infecção em cirurgia ortopédica consiste…
(more)
▼ A infecção de sítio cirúrgico é um dos principais problemas que pode acometer o paciente no perioperatório. Este tipo de infecção em cirurgia ortopédica consiste em problema grave devido à sua morbidade e custos elevados. O presente estudo teve como objetivo geral analisar a ocorrência e os fatores predisponentes de infecção de sítio cirúrgico em pacientes submetidos a cirurgias ortopédicas. Para tal, realizou-se estudo na abordagem metodológica quantitativa, com delineamento de pesquisa não-experimental, do tipo correlacional e longitudinal. A amostra foi composta por 93 pacientes submetidos a cirurgias ortopédicas limpas e eletivas. Para a coleta de dados, um instrumento foi elaborado e submetido à validação aparente e de conteúdo. A coleta de dados ocorreu no período de outubro de 2011 a março de 2012, em hospital privado filantrópico da cidade de Franca, estado de São Paulo. Na análise estatística dos dados empregou-se a análise bivariada (por
meio de odds ratio, intervalo de confiança, teste Qui-quadrado com correção de Yates, teste t de \"Studentë Mann-Whitney), regressão múltipla e regressão logística binária. A infecção de sítio cirúrgico foi detectada em 16 pacientes participantes da pesquisa, sendo a sua ocorrência de 17,2%. As variáveis investigadas relacionadas ao paciente foram a idade, Índice de Massa Corpórea, classificação ASA e a presença de doenças crônicas. As variáveis estudadas relacionadas ao procedimento anestésico cirúrgico foram a duração da anestesia, duração da cirurgia, uso de antibioticoprofilaxia e tempo total de internação. Os resultados evidenciaram diferença estatisticamente significante entre o grupo com e o grupo sem infecção, quando testado associação com a infecção de sítio cirúrgico e as variáveis classificação ASA e o tempo total de internação. Após ajuste do modelo de regressão logística binária, apenas a variável tempo total de internação mostrou-se com relação estatisticamente
significativa com a presença ou não de infecção. Ressalta-se ainda que 75% dos casos de infecção foram diagnosticados após a alta hospitalar dos pacientes indicando a importância da vigilância epidemiológica pós- alta.
Surgical site infection is one of the main problems that can occur to patients in the perioperative period. This type of infection in orthopedic surgeries is a severe problem due to its morbidity and high costs. This quantitative, correlational, non- experimental and longitudinal study aimed to analyze the incidence and predisposing factors for surgical site infection in patients who underwent orthopedic surgery. The sample consisted of 93 patients who underwent clean and elective orthopedic surgeries. For data collection, an instrument was developed and submitted to face and content validation. Data collection occurred between October 2011 and March 2012, in a private philanthropic hospital in the city of Franca, state of São Paulo. Bivariate analysis (by means
of odds ratios, confidence intervals, Chi-squared test with Yates…
Advisors/Committee Members: Cristina Maria Galvao, Denise de Andrade, Vanessa de Brito Poveda.
Subjects/Keywords: enfermagem perioperatória; fatores de risco; infecção da ferida operatória; infecção de sítio cirúrgico; perioperative nursing; risk factors; surgical site infection; surgical wound infection
Record Details
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Record Details
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ribeiro, J. C. (2012). Análise da ocorrência e dos fatores predisponentes de infecção de sítio cirúrgico em pacientes sumetidos a cirurgias ortopédicas. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/22/22132/tde-05112012-194139/
Chicago Manual of Style (16th Edition):
Ribeiro, Julio Cesar. “Análise da ocorrência e dos fatores predisponentes de infecção de sítio cirúrgico em pacientes sumetidos a cirurgias ortopédicas.” 2012. Masters Thesis, University of São Paulo. Accessed April 18, 2021.
http://www.teses.usp.br/teses/disponiveis/22/22132/tde-05112012-194139/.
MLA Handbook (7th Edition):
Ribeiro, Julio Cesar. “Análise da ocorrência e dos fatores predisponentes de infecção de sítio cirúrgico em pacientes sumetidos a cirurgias ortopédicas.” 2012. Web. 18 Apr 2021.
Vancouver:
Ribeiro JC. Análise da ocorrência e dos fatores predisponentes de infecção de sítio cirúrgico em pacientes sumetidos a cirurgias ortopédicas. [Internet] [Masters thesis]. University of São Paulo; 2012. [cited 2021 Apr 18].
Available from: http://www.teses.usp.br/teses/disponiveis/22/22132/tde-05112012-194139/.
Council of Science Editors:
Ribeiro JC. Análise da ocorrência e dos fatores predisponentes de infecção de sítio cirúrgico em pacientes sumetidos a cirurgias ortopédicas. [Masters Thesis]. University of São Paulo; 2012. Available from: http://www.teses.usp.br/teses/disponiveis/22/22132/tde-05112012-194139/
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