subject:(Neuropharamacological Measurements Using PET)

University of Michigan

1. Joshi, Aniket. Improved Quantitative Methods for Multiple Neuropharmacological Non-Invasive Brain PET Studies.

Degree: PhD, Biomedical Engineering, 2008, University of Michigan

URL: http://hdl.handle.net/2027.42/61729

► Positron emission tomography (PET) is a medical imaging modality offering a powerful tool for brain research by mapping of in vivo neuropharmacological functions such as… (more)

▼ Positron emission tomography (PET) is a medical imaging modality offering a powerful tool for brain research by mapping of in vivo neuropharmacological functions such as metabolism, enzyme activity, and neuroreceptor binding site density and occupancy. Quantification in brain-PET can be classified into: 1) accurate quantification of radiotracer distribution such that image values are proportional to the radiotracer concentration in tissue, and 2) accurate quantification of the pharmacological state of the system-of-interest. This thesis addresses both these aspects for functional neuroreceptor imaging studies of the living brain. Traditional brain PET studies have at least two primary limitations. First, they measure only a single neuropharmacological aspect in isolation, which is often insufficient for characterizing a neurological condition. Second, data acquisition is accompanied by the invasive arterial blood sampling for measuring the input function to the system-of-interest. The motivation for this thesis was to address both these limitations, which led to the development of quantitative methods for multiple neuropharmacological PET studies performed without blood sampling. One such experimental design investigated was a dual-measurement intervention study where the system-of-interest is perturbed with the intent of changing the subject’s pharmacological status and system parameters are estimated both pre- and post-intervention. Second was a dual-tracer study where two radiotracers targeting two different neuropharmacological systems were injected closely in time in the same study. A major challenge in analyzing multiple pharmacological PET studies is the statistical noise-induced bias and variance in the parameter estimates. Methods developed in this thesis reduced almost all the bias (>90%) in the intervention studies with a corresponding improvement in precision. Parameter estimates for dual-tracer studies were obtained with inter-subject regions-of-interest means within ±10% of those obtained from single-tracer scans without appreciable increase in variance. The thesis also addresses inter-scanner PET image variability, a major confound in multi-center studies used to investigate disease progression. Since various PET centers have scanners with different hardware and software, systematic differences exist in multi-center data. This thesis develops a framework to reduce the inter-scanner PET image variability before pooling multi-center data for analysis. The methods developed reduced variability in phantom scans from different sites by approximately 50%. Advisors/Committee Members: Fessler, Jeffrey A. (committee member), Koeppe, Robert A. (committee member), Clinthorne, Neal H. (committee member), Meyer, Charles R. (committee member), Noll, Douglas C. (committee member).

Subjects/Keywords: Positron Emission Tomography; PET Pharmacokinetics; PET Kinetic Modeling; Neuropharamacological Measurements Using PET; Neuroimaging; PET for Clinical Diagnosis and Drug Discovery; Radiology; Health Sciences

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APA (6^th Edition):

Joshi, A. (2008). Improved Quantitative Methods for Multiple Neuropharmacological Non-Invasive Brain PET Studies. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/61729

Chicago Manual of Style (16^th Edition):

Joshi, Aniket. “Improved Quantitative Methods for Multiple Neuropharmacological Non-Invasive Brain PET Studies.” 2008. Doctoral Dissertation, University of Michigan. Accessed January 19, 2021. http://hdl.handle.net/2027.42/61729.

MLA Handbook (7^th Edition):

Joshi, Aniket. “Improved Quantitative Methods for Multiple Neuropharmacological Non-Invasive Brain PET Studies.” 2008. Web. 19 Jan 2021.

Vancouver:

Joshi A. Improved Quantitative Methods for Multiple Neuropharmacological Non-Invasive Brain PET Studies. [Internet] [Doctoral dissertation]. University of Michigan; 2008. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/2027.42/61729.

Council of Science Editors:

Joshi A. Improved Quantitative Methods for Multiple Neuropharmacological Non-Invasive Brain PET Studies. [Doctoral Dissertation]. University of Michigan; 2008. Available from: http://hdl.handle.net/2027.42/61729

2. Shaik, Mahammad Arafath. Studies aerosol properties using ground based measurements at semi arid region anantapur;.

Degree: 2009, Sri Krishnadevaraya University

URL: http://shodhganga.inflibnet.ac.in/handle/10603/22708

newline

bibliography xii, 212

Advisors/Committee Members: Gopal, Rama K.

Subjects/Keywords: aerosol properties using gorund based measurements

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APA (6^th Edition):

Shaik, M. A. (2009). Studies aerosol properties using ground based measurements at semi arid region anantapur;. (Thesis). Sri Krishnadevaraya University. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/22708

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Shaik, Mahammad Arafath. “Studies aerosol properties using ground based measurements at semi arid region anantapur;.” 2009. Thesis, Sri Krishnadevaraya University. Accessed January 19, 2021. http://shodhganga.inflibnet.ac.in/handle/10603/22708.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Shaik, Mahammad Arafath. “Studies aerosol properties using ground based measurements at semi arid region anantapur;.” 2009. Web. 19 Jan 2021.

Vancouver:

Shaik MA. Studies aerosol properties using ground based measurements at semi arid region anantapur;. [Internet] [Thesis]. Sri Krishnadevaraya University; 2009. [cited 2021 Jan 19]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/22708.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Shaik MA. Studies aerosol properties using ground based measurements at semi arid region anantapur;. [Thesis]. Sri Krishnadevaraya University; 2009. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/22708

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Tampereen ammattikorkeakoulu

3. Keinonen, Niko. Päivittäistavarakaupoissa syntyvän jätemuovin kierrättäminen.

Degree: 2014, Tampereen ammattikorkeakoulu

URL: http://www.theseus.fi/handle/10024/79810

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Opinnäytetyön tarkoituksena oli selvittää päivittäistavarakaupoista syntyvän muovijätteen määrä, muovimateriaalien laadut, niiden kierrätettävyys sekä optimoida muovien kierrättäminen kaupoista kierrättävälle yritykselle. Kierrätysprosessi kohdistui suuriin, keskikokoisiin sekä pieniin… (more)

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Opinnäytetyön tarkoituksena oli selvittää päivittäistavarakaupoista syntyvän muovijätteen määrä, muovimateriaalien laadut, niiden kierrätettävyys sekä optimoida muovien kierrättäminen kaupoista kierrättävälle yritykselle. Kierrätysprosessi kohdistui suuriin, keskikokoisiin sekä pieniin vähittäistavarakauppoihin Pirkanmaalla. Käytännön tutkimuksissa Tarastenjärven jätteenkäsittelykeskuksessa Tampereella huomattiin sekajätekuormassa olevan kierrätyskelpoista muovimateriaalia noin 20 % kokonaispainosta. Todellisuudessa muovien osuus sekajätteestä on suurempi, sillä sekajätteen joukossa oli myös paljon pahvia. Pahvi sekajätteen joukossa on epäedullista, sillä oikein kierrätettynä pahvista saa hyvitteen. Sekajätteen tyhjentämisestä on omat kustannukset. Muovilaadut olivat perinteisiä valtamuoveja (PE-LD, PE-HD, PP, PS, PS-E ja PET), joihin luetaan nykyään myös virvoitusjuomapullojen materiaali polyeteenitereftalaatti. Saaduista tuloksista voidaan laskea vuosittaiset säästöt kauppaketjulle, kun ylijäävä sekajäte muutetaan energiajätteeksi. Vuotuiset säästöt olisivat kymmeniä tuhansia euroja. Ehdotan, että värillinen muovi tullaan keräämään kirkkaan muovin tavoin jätesäkkeihin ja säkit paalataan. Näin saadaan värillisten muovien varastointi ja kuljetus tehokkaaksi.

The purpose of the thesis was to clarify the amount of the plastic waste which is created from the grocery shops, the qualities of the plastic materials, recyclability of the plastics and to optimize the recycling of plastics from the shops to the recycling company. The recycling process was directed to a big, middle size and small grocery shops in the Pirkanmaa region in Finland. In practical studies it was noticed that about 20 % of the total weight of the mixed waste in the Tarastenjärvi landfill site in Tampere was recyclable plastic material. In reality the share of plastics in the mixed waste is bigger because there is also much cardboard among mixed waste. The cardboard among mixed waste is disadvantageous because the company can get compensation from the cardboard recycled right. There are own costs from the emptying of mixed waste. Plastic materials were traditional mass consumption plastics (PE-LD, PE-HD, PP, PS, PS-E and PET). Polyethylene terephthalate is the material of soft drink bottles and it is nowadays considered as mass consumption plastic. The annual savings can be calculated from the obtained results to the chain of stores when the mixed waste is converted to energy waste. The annual savings would be tens of thousands of euros. I suggest that the colored plastic will be collected to the refuse sacks like clear plastic and the sacks baled. This way the storage and transport of colored plastics can be made efficient.

Advisors/Committee Members: Tampereen ammattikorkeakoulu.

Subjects/Keywords: PET

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APA (6^th Edition):

Keinonen, N. (2014). Päivittäistavarakaupoissa syntyvän jätemuovin kierrättäminen. (Thesis). Tampereen ammattikorkeakoulu. Retrieved from http://www.theseus.fi/handle/10024/79810

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Keinonen, Niko. “Päivittäistavarakaupoissa syntyvän jätemuovin kierrättäminen.” 2014. Thesis, Tampereen ammattikorkeakoulu. Accessed January 19, 2021. http://www.theseus.fi/handle/10024/79810.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Keinonen, Niko. “Päivittäistavarakaupoissa syntyvän jätemuovin kierrättäminen.” 2014. Web. 19 Jan 2021.

Vancouver:

Keinonen N. Päivittäistavarakaupoissa syntyvän jätemuovin kierrättäminen. [Internet] [Thesis]. Tampereen ammattikorkeakoulu; 2014. [cited 2021 Jan 19]. Available from: http://www.theseus.fi/handle/10024/79810.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Keinonen N. Päivittäistavarakaupoissa syntyvän jätemuovin kierrättäminen. [Thesis]. Tampereen ammattikorkeakoulu; 2014. Available from: http://www.theseus.fi/handle/10024/79810

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Michigan

4. de Ana Arbeloa, Francisco Javier. Quantitative real-time blood flow measurements using intravascular ultrasound.

Degree: PhD, Biomedical engineering, 2004, University of Michigan

URL: http://hdl.handle.net/2027.42/124658

► Percutaneous transluminal coronary angioplasty (PTCA), stenting, and related techniques, are commonly used in the treatment of coronary artery disease. The main goal of these interventions… (more)

▼ Percutaneous transluminal coronary angioplasty (PTCA), stenting, and related techniques, are commonly used in the treatment of coronary artery disease. The main goal of these interventions is to restore blood flow in the coronary vasculature, yet the lack of quantitative real-time feedback presents real problems as the final procedure outcomes cannot be accurately determined during the intervention. Real-time quantitative blood flow measurements during balloon PTCA stent deployment would significantly improve the quality of these procedures and potentially reduce the high costs of these types of interventions. Doppler techniques are commonly used to measure flow with most ultrasound transducers. However, with intravascular ultrasound (IVUS) catheters, the flow direction inside a vessel is orthogonal to the transducer's image plane, making Doppler methods impractical. A slow-time filter-bank processing method was implemented in real-time using an intravascular ultrasound transducer array to obtain flow velocity measurements orthogonal to the image plane. The slow-time spectrum is estimated from the filtered energy under a series of narrow band pass filters centered at increasing frequencies applied to the slow-time signals. The normalized second moment of slow-time spectra is monotonically related to scatteter velocity. However, in the presence of in-plane flow this relationship changes. Slow-time spectra shift and spread with the in-plane and out-of-plane components, respectively. These two effects cause the normalized spectral second moment to increase, resulting in flow overestimates. Applying appropriate tilts to slow-time signals causes the slow-time spectrum to shift back to DC and the orthogonal estimation method can be used. Independent simulations show absolute flow rate estimation error smaller than 3.2% for plug flows of 30cm/sec and flow angles from 0° to 15°, making this method suitable for real-time validation of intravascular interventions. Advisors/Committee Members: O'Donnell, Matthew (advisor).

Subjects/Keywords: Blood Flow; Intravascular Ultrasound; Measurements; Quantitative; Real; Time; Using

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APA (6^th Edition):

de Ana Arbeloa, F. J. (2004). Quantitative real-time blood flow measurements using intravascular ultrasound. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/124658

Chicago Manual of Style (16^th Edition):

de Ana Arbeloa, Francisco Javier. “Quantitative real-time blood flow measurements using intravascular ultrasound.” 2004. Doctoral Dissertation, University of Michigan. Accessed January 19, 2021. http://hdl.handle.net/2027.42/124658.

MLA Handbook (7^th Edition):

de Ana Arbeloa, Francisco Javier. “Quantitative real-time blood flow measurements using intravascular ultrasound.” 2004. Web. 19 Jan 2021.

Vancouver:

de Ana Arbeloa FJ. Quantitative real-time blood flow measurements using intravascular ultrasound. [Internet] [Doctoral dissertation]. University of Michigan; 2004. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/2027.42/124658.

Council of Science Editors:

de Ana Arbeloa FJ. Quantitative real-time blood flow measurements using intravascular ultrasound. [Doctoral Dissertation]. University of Michigan; 2004. Available from: http://hdl.handle.net/2027.42/124658

University of Michigan

5. Erdogan, Hakan. Statistical image reconstruction algorithms using paraboloidal surrogates for PET transmission scans.

Degree: PhD, Electrical engineering, 1999, University of Michigan

URL: http://hdl.handle.net/2027.42/132124

► Positron Emission Tomography (PET) is a diagnostic imaging tool that provides images of radioactive substances injected into the body to trace biological functions. The radioactive… (more)

▼ Positron Emission Tomography (PET) is a diagnostic imaging tool that provides images of radioactive substances injected into the body to trace biological functions. The radioactive substance emits a positron which annihilates with an electron to produce two 511 keV photons traveling in approximately opposite directions to be coincidentally detected by two detectors. Many photons are absorbed or scattered, reducing the number of detected emission events. Attenuation correction is crucial for quantitatively accurate PET reconstructions. PET transmission scans are performed to estimate attenuation parameters which are in turn used to correct the emission scans for attenuation effects. The noise in estimating the attenuation parameters propagates to the emission images affecting their quality and quantitative correctness. Thus, attenuation image reconstruction is extremely important in PET. Conventional methods of attenuation correction are suboptimal and ignore the Poisson nature of the data. We propose to use penalized likelihood Image reconstruction techniques for transmission scans. Current algorithms for transmission tomography have two important problems: (1) they are not guaranteed to converge, (2) if they converge, the convergence is slow. We develop new fast and monotonic optimization algorithms for penalized likelihood image reconstruction based on a novel paraboloidal surrogates principle. We present results showing the speed of the new optimization algorithms as compared to previous ones. We apply the algorithms to PET data obtained from an anthropomorphic thorax phantom and real patient data. A transmission scan performed after the patient is injected is called a post-injection transmission scan. Post-injection transmission scans are desirable since the patient throughput is increased and motion artifacts are reduced as compared to pre-injection scans. However, there are emission counts contaminating the measurements. We include emission contamination in the post-injection transmission measurement statistical model and obtain better images as compared to conventional subtraction based approaches. We also present a joint estimation technique to estimate attenuation and emission images simultaneously from transmission and emission scans. We analyze noise propagation from transmission scans to emission images for some sequential image reconstruction methods. The results show that transmission noise affects emission image quality heavily, especially when short transmission scans are utilized. Advisors/Committee Members: Fessler, Jeffrey A. (advisor).

Subjects/Keywords: Algorithms; Image Reconstruction; Paraboloidal Surrogates; Pet; Statistical; Transmission Scans; Using

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APA (6^th Edition):

Erdogan, H. (1999). Statistical image reconstruction algorithms using paraboloidal surrogates for PET transmission scans. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/132124

Chicago Manual of Style (16^th Edition):

Erdogan, Hakan. “Statistical image reconstruction algorithms using paraboloidal surrogates for PET transmission scans.” 1999. Doctoral Dissertation, University of Michigan. Accessed January 19, 2021. http://hdl.handle.net/2027.42/132124.

MLA Handbook (7^th Edition):

Erdogan, Hakan. “Statistical image reconstruction algorithms using paraboloidal surrogates for PET transmission scans.” 1999. Web. 19 Jan 2021.

Vancouver:

Erdogan H. Statistical image reconstruction algorithms using paraboloidal surrogates for PET transmission scans. [Internet] [Doctoral dissertation]. University of Michigan; 1999. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/2027.42/132124.

Council of Science Editors:

Erdogan H. Statistical image reconstruction algorithms using paraboloidal surrogates for PET transmission scans. [Doctoral Dissertation]. University of Michigan; 1999. Available from: http://hdl.handle.net/2027.42/132124

Stockholm University

6. Åkesson, Lars. Partial Volume Correction in PET/CT.

Degree: Medical Radiation Physics (together with KI), 2008, Stockholm University

URL: http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-8322

► In this thesis, a two-dimensional pixel-wise deconvolution method for partial volume correction (PVC) for combined Positron Emission Tomography and Computer Tomography (PET/CT) imaging has… (more)

Subjects/Keywords: PVC algorithm; PET; image; PSF measurements; Radiological physics; Radiofysik

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APA (6^th Edition):

Åkesson, L. (2008). Partial Volume Correction in PET/CT. (Thesis). Stockholm University. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-8322

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Åkesson, Lars. “Partial Volume Correction in PET/CT.” 2008. Thesis, Stockholm University. Accessed January 19, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-8322.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Åkesson, Lars. “Partial Volume Correction in PET/CT.” 2008. Web. 19 Jan 2021.

Vancouver:

Åkesson L. Partial Volume Correction in PET/CT. [Internet] [Thesis]. Stockholm University; 2008. [cited 2021 Jan 19]. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-8322.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Åkesson L. Partial Volume Correction in PET/CT. [Thesis]. Stockholm University; 2008. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-8322

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Michigan

7. Zahn, Daniel Jacob. Investigation of bistatic scattering using numerical techniques and novel near -field measurements.

Degree: PhD, Electrical engineering, 2001, University of Michigan

URL: http://hdl.handle.net/2027.42/126867

► Currently there exists a desire to pursue novel measurement, numerical, and analytical techniques for characterization of bistatic response of point and distributed targets. This thesis… (more)

▼ Currently there exists a desire to pursue novel measurement, numerical, and analytical techniques for characterization of bistatic response of point and distributed targets. This thesis strives to incorporate aspects from each of these electromagnetic (EM) strategies and to apply these techniques to further the understanding of remote sensing of point and distributed targets through bistatic measurements and theoretical scattering models. A planar near-field scanning system is proposed, built, and tested that performs bistatic scattering measurements from both point and distributed targets with a high degree of accuracy. Also, numerical techniques are pursued for advancing the knowledge of EM scattering from rough surfaces using computational electromagnetics by looking at the two major limiting factors of such analysis-time and memory requirements. Through the use of wavelet basis functions, it is found that the moment matrix of the Method of Moments can be made significantly sparse (up to 99% sparse) when a threshold is applied. Efficient sparse matrix solvers now can be used without sacrificing accuracy of the scattering pattern. Using an Iterative Physical Optics approach allows significant time reduction in analysis for 1-Dimensional and 2-Dimensional random rough Perfectly Electrically Conducting (PEC) or impedance boundary surfaces with physical characteristics that have a root mean square (rms) slope less than 0.5. Finally, the performance of a parasitic GPS multi-static radar system is investigated. A feasibility study is conducted with the desire of applying such a system to the remote sensing of the earth without launching high cost satellites, but rather using existing satellites already in orbit. The results of this feasibility study concluded that current GPS satellites do not transmit enough power to accurately measure incoherent bistatic scattering from the earth, but the next generation GPS satellites may be more applicable to this endeavor. Advisors/Committee Members: Sarabandi, Kamal (advisor).

Subjects/Keywords: Bistatic Scattering; Electromagnetics; Investigation; Measurements; Near-field; Novel; Numerical; Techniques; Using

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APA (6^th Edition):

Zahn, D. J. (2001). Investigation of bistatic scattering using numerical techniques and novel near -field measurements. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/126867

Chicago Manual of Style (16^th Edition):

Zahn, Daniel Jacob. “Investigation of bistatic scattering using numerical techniques and novel near -field measurements.” 2001. Doctoral Dissertation, University of Michigan. Accessed January 19, 2021. http://hdl.handle.net/2027.42/126867.

MLA Handbook (7^th Edition):

Zahn, Daniel Jacob. “Investigation of bistatic scattering using numerical techniques and novel near -field measurements.” 2001. Web. 19 Jan 2021.

Vancouver:

Zahn DJ. Investigation of bistatic scattering using numerical techniques and novel near -field measurements. [Internet] [Doctoral dissertation]. University of Michigan; 2001. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/2027.42/126867.

Council of Science Editors:

Zahn DJ. Investigation of bistatic scattering using numerical techniques and novel near -field measurements. [Doctoral Dissertation]. University of Michigan; 2001. Available from: http://hdl.handle.net/2027.42/126867

University of Michigan

8. Yavuz, Mehmet. Statistical tomographic image reconstruction methods for randoms -precorrected PET measurements.

Degree: PhD, Electrical engineering, 2000, University of Michigan

URL: http://hdl.handle.net/2027.42/132500

► Medical Imaging systems such as positron emission tomography (PET) and electronically collimated single positron emission tomography (SPECT) record particle emission events based on timing coincidences.… (more)

▼ Medical Imaging systems such as positron emission tomography (PET) and electronically collimated single positron emission tomography (SPECT) record particle emission events based on timing coincidences. These systems record accidental coincidence (AC) events simultaneously with the true coincidence events. Similarly in low light-level imaging, thermoelectrons generated by photodetector are indistinguishable from photoelectrons generated by photo-conversion, and their effect is similar to the AC events. During PET emission scans, accidental coincidence (AC) events occur when photons that originate from separate positron-electron annihilations are mistakenly recorded as having arisen from the same annihilation. In PET, generally a significant portion of the collected data consists of AC events that are a primary source of background noise. Also, during PET transmission scans, photons that originate from different transmission sources cause AC events. In PET, the measurements are usually precorrected for AC events by real-time subtraction of the delayed window coincidences. Randoms subtraction compensates in mean for accidental coincidences, but destroys the Poisson statistics. We develop statistical image reconstruction methods for randoms pre-corrected PET measurements using penalized maximum likelihood (ML) estimation. We introduce two new approximations to the complicated exact log-likelihood of the precorrected measurements: one based on a shifted Poisson model, and the other based on saddle-point approximations to the measurement probability mass function (pmf). We compare estimators based on the new models to the conventional data-weighted least squares (WLS) and conventional maximum likelihood (based on the ordinary Poisson (OP) model) using experiments, simulations and analytic approximations. For transmission scans, we demonstrate that the proposed methods avoid the systematic bias of the WLS method, and lead to significantly lower variance than the conventional OP method. We also investigate the propagation of noise from the reconstructed attenuation maps into the emission images. Interestingly, the noise improvements in the emission images with the new methods are even greater than the improvements in the attenuation maps themselves. To corroborate the empirical studies, we develop analytical approximations to the reconstructed image covariance and we also develop analytical approximations for the propagation of noise from attenuation maps into the reconstructed emission images. The results of the analytic approximations are shown to be in good agreement with the experimental results supporting the improvements with the new methods. Similarly, for the emission reconstructions, we demonstrate that the proposed methods lead to significantly lower variance than the conventional OP method and also avoid systematic positive bias of the OP method. Although the SP model is shown to be slightly biased for emission scans with very low count rates, the… Advisors/Committee Members: Fessler, Jeffrey A. (advisor).

Subjects/Keywords: Accidental Coincidence; Image Reconstruction; Measurements; Methods; Pet; Randoms-precorrected; Statistical; Tomographic

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APA (6^th Edition):

Yavuz, M. (2000). Statistical tomographic image reconstruction methods for randoms -precorrected PET measurements. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/132500

Chicago Manual of Style (16^th Edition):

Yavuz, Mehmet. “Statistical tomographic image reconstruction methods for randoms -precorrected PET measurements.” 2000. Doctoral Dissertation, University of Michigan. Accessed January 19, 2021. http://hdl.handle.net/2027.42/132500.

MLA Handbook (7^th Edition):

Yavuz, Mehmet. “Statistical tomographic image reconstruction methods for randoms -precorrected PET measurements.” 2000. Web. 19 Jan 2021.

Vancouver:

Yavuz M. Statistical tomographic image reconstruction methods for randoms -precorrected PET measurements. [Internet] [Doctoral dissertation]. University of Michigan; 2000. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/2027.42/132500.

Council of Science Editors:

Yavuz M. Statistical tomographic image reconstruction methods for randoms -precorrected PET measurements. [Doctoral Dissertation]. University of Michigan; 2000. Available from: http://hdl.handle.net/2027.42/132500

Vrije Universiteit Amsterdam

9. Rijbroek, A. Carotid surgery : Potential of cerebrovascular PET measurements .

Degree: 2008, Vrije Universiteit Amsterdam

URL: http://hdl.handle.net/1871/15575

Subjects/Keywords: Carotid surgery: potential of cerebrovascular PET measurements. Impact of vascular training; haarlem; carotisendarteriëctomie;

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Rijbroek, A. (2008). Carotid surgery : Potential of cerebrovascular PET measurements . (Doctoral Dissertation). Vrije Universiteit Amsterdam. Retrieved from http://hdl.handle.net/1871/15575

Chicago Manual of Style (16^th Edition):

Rijbroek, A. “Carotid surgery : Potential of cerebrovascular PET measurements .” 2008. Doctoral Dissertation, Vrije Universiteit Amsterdam. Accessed January 19, 2021. http://hdl.handle.net/1871/15575.

MLA Handbook (7^th Edition):

Rijbroek, A. “Carotid surgery : Potential of cerebrovascular PET measurements .” 2008. Web. 19 Jan 2021.

Vancouver:

Rijbroek A. Carotid surgery : Potential of cerebrovascular PET measurements . [Internet] [Doctoral dissertation]. Vrije Universiteit Amsterdam; 2008. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/1871/15575.

Council of Science Editors:

Rijbroek A. Carotid surgery : Potential of cerebrovascular PET measurements . [Doctoral Dissertation]. Vrije Universiteit Amsterdam; 2008. Available from: http://hdl.handle.net/1871/15575

Virginia Tech

10. Ringshia, Aditya K. Aerodynamic Measurements in a Wind Tunnel on Scale Models of a 777 Main Landing Gear.

Degree: MS, Mechanical Engineering, 2006, Virginia Tech

URL: http://hdl.handle.net/10919/34583

► Aerodynamic measurements were taken over models of the Boeing 777 high fidelity isolated landing gear in the 6- by 6-foot Virginia Tech Stability Wind Tunnel… (more)

Subjects/Keywords: Particle Image Velocimetry; Pitot-static Measurements; Landing Gear; Hot Film Measurements; Flow Visualization using Tufts

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APA (6^th Edition):

Ringshia, A. K. (2006). Aerodynamic Measurements in a Wind Tunnel on Scale Models of a 777 Main Landing Gear. (Masters Thesis). Virginia Tech. Retrieved from http://hdl.handle.net/10919/34583

Chicago Manual of Style (16^th Edition):

Ringshia, Aditya K. “Aerodynamic Measurements in a Wind Tunnel on Scale Models of a 777 Main Landing Gear.” 2006. Masters Thesis, Virginia Tech. Accessed January 19, 2021. http://hdl.handle.net/10919/34583.

MLA Handbook (7^th Edition):

Ringshia, Aditya K. “Aerodynamic Measurements in a Wind Tunnel on Scale Models of a 777 Main Landing Gear.” 2006. Web. 19 Jan 2021.

Vancouver:

Ringshia AK. Aerodynamic Measurements in a Wind Tunnel on Scale Models of a 777 Main Landing Gear. [Internet] [Masters thesis]. Virginia Tech; 2006. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/10919/34583.

Council of Science Editors:

Ringshia AK. Aerodynamic Measurements in a Wind Tunnel on Scale Models of a 777 Main Landing Gear. [Masters Thesis]. Virginia Tech; 2006. Available from: http://hdl.handle.net/10919/34583

University of Michigan

11. Aarons, Sarah Miranda. Evidence of Regional and Global Climate Change in the Mineral Aerosol (Dust) Record from Ice Cores Through the Anthropocene and Pleistocene.

Degree: PhD, Geology, 2016, University of Michigan

URL: http://hdl.handle.net/2027.42/120678

► Dust in the atmosphere has a significant effect on earth’s climate by scattering or absorption of incoming solar radiation, acting as cloud condensation nuclei, or… (more)

▼ Dust in the atmosphere has a significant effect on earth’s climate by scattering or absorption of incoming solar radiation, acting as cloud condensation nuclei, or providing critical nutrients to oceans and terrestrial biospheres. Changes in the locations of dust source areas and pathways can provide insight into understanding the relationship between mineral dust, global climate, and biogeochemical cycles. To gain a better understanding of the impact of the dust cycle on global and regional climate, the dust records within ice-cores from three locations are utilized to reconstruct changes in atmospheric circulation and dust provenance using radiogenic isotope data, trace and rare earth element composition, anion concentration, dust concentration, and size distribution. In this dissertation thesis, we applied this methodology to investigate three case studies. Ice-core samples from the Upper Fremont Glacier (UFG) in Wyoming, Taylor Dome, an East Antarctic ice-dome, and Taylor Glacier, the outlet glacier for Taylor Dome, are investigated here. In the UFG, we found that samples reveal anthropogenic influences. Variability in dust sources and pathways indicates a transition from far to near-range transport due to land-use changes associated with agricultural activity and livestock grazing expansion during 1700 – 1975 A.D. Samples from Taylor Dome and Taylor Glacier, spanning the time period 1,800 – 55,000 years before present, indicate a shift from long-range transported dust to a more variable local input during the transition out of the last glacial period when global temperatures rose 4-7 degrees C. Dust sources and transport pathway changes reveal atmospheric circulation restructuring following the last climatic transition and subsequent retreat of the Ross Ice Shelf. Advisors/Committee Members: Aciego, Sarah M (committee member), Blum, Joel D (committee member), Bassis, Jeremy N (committee member), Flanner, Mark G (committee member), Cory, Rose (committee member).

Subjects/Keywords: Dust record in ice cores; Dust as an indicator of climate change; Reconstruction of atmospheric processes using physical and chemical measurements of dust in ice; Influence of retreating ice sheet on local coastal Antarctic climate; Anthropogenic input to a midlatitude North American glacier; Dust provenance using radiogenic isotopes; Geology and Earth Sciences; Science

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APA (6^th Edition):

Aarons, S. M. (2016). Evidence of Regional and Global Climate Change in the Mineral Aerosol (Dust) Record from Ice Cores Through the Anthropocene and Pleistocene. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/120678

Chicago Manual of Style (16^th Edition):

Aarons, Sarah Miranda. “Evidence of Regional and Global Climate Change in the Mineral Aerosol (Dust) Record from Ice Cores Through the Anthropocene and Pleistocene.” 2016. Doctoral Dissertation, University of Michigan. Accessed January 19, 2021. http://hdl.handle.net/2027.42/120678.

MLA Handbook (7^th Edition):

Aarons, Sarah Miranda. “Evidence of Regional and Global Climate Change in the Mineral Aerosol (Dust) Record from Ice Cores Through the Anthropocene and Pleistocene.” 2016. Web. 19 Jan 2021.

Vancouver:

Aarons SM. Evidence of Regional and Global Climate Change in the Mineral Aerosol (Dust) Record from Ice Cores Through the Anthropocene and Pleistocene. [Internet] [Doctoral dissertation]. University of Michigan; 2016. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/2027.42/120678.

Council of Science Editors:

Aarons SM. Evidence of Regional and Global Climate Change in the Mineral Aerosol (Dust) Record from Ice Cores Through the Anthropocene and Pleistocene. [Doctoral Dissertation]. University of Michigan; 2016. Available from: http://hdl.handle.net/2027.42/120678

12. 高松, 昇三. MRI中で測定可能なPET装置の検出器部の開発 : Development of a Multi-Slice, Depth-of-Interaction MR-Compatible PET; MRIチュウデソクテイカノウナ PET ソウチノケンシュツキブノカイハツ.

Degree: Nara Institute of Science and Technology / 奈良先端科学技術大学院大学

URL: http://hdl.handle.net/10061/1722

Subjects/Keywords: PET

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APA (6^th Edition):

高松, �. (n.d.). MRI中で測定可能なPET装置の検出器部の開発 : Development of a Multi-Slice, Depth-of-Interaction MR-Compatible PET; MRIチュウデソクテイカノウナ PET ソウチノケンシュツキブノカイハツ. (Thesis). Nara Institute of Science and Technology / 奈良先端科学技術大学院大学. Retrieved from http://hdl.handle.net/10061/1722

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

高松, 昇三. “MRI中で測定可能なPET装置の検出器部の開発 : Development of a Multi-Slice, Depth-of-Interaction MR-Compatible PET; MRIチュウデソクテイカノウナ PET ソウチノケンシュツキブノカイハツ.” Thesis, Nara Institute of Science and Technology / 奈良先端科学技術大学院大学. Accessed January 19, 2021. http://hdl.handle.net/10061/1722.

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

高松, 昇三. “MRI中で測定可能なPET装置の検出器部の開発 : Development of a Multi-Slice, Depth-of-Interaction MR-Compatible PET; MRIチュウデソクテイカノウナ PET ソウチノケンシュツキブノカイハツ.” Web. 19 Jan 2021.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Vancouver:

高松 �. MRI中で測定可能なPET装置の検出器部の開発 : Development of a Multi-Slice, Depth-of-Interaction MR-Compatible PET; MRIチュウデソクテイカノウナ PET ソウチノケンシュツキブノカイハツ. [Internet] [Thesis]. Nara Institute of Science and Technology / 奈良先端科学技術大学院大学; [cited 2021 Jan 19]. Available from: http://hdl.handle.net/10061/1722.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

Council of Science Editors:

高松 �. MRI中で測定可能なPET装置の検出器部の開発 : Development of a Multi-Slice, Depth-of-Interaction MR-Compatible PET; MRIチュウデソクテイカノウナ PET ソウチノケンシュツキブノカイハツ. [Thesis]. Nara Institute of Science and Technology / 奈良先端科学技術大学院大学; Available from: http://hdl.handle.net/10061/1722

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

13. 松原, 佳亮. [18F]FDOPA PET動態解析で推定されたパラメータのドーパミン代謝の変化に対する検出感度の評価 : Evaluation for sensitivity of kinetic macro-parameters estimated in [18F]FDOPA PET study to changes in dopamine matabolism.; [18F] FDOPA PET ドウタイカイセキデスイテイサレタパラメータノドーパミンタイシャノヘンカニタイスルケンシュツカンドノヒョウカ.

Degree: Nara Institute of Science and Technology / 奈良先端科学技術大学院大学

URL: http://hdl.handle.net/10061/5551

Subjects/Keywords: PET

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APA (6^th Edition):

松原, �. (n.d.). [18F]FDOPA PET動態解析で推定されたパラメータのドーパミン代謝の変化に対する検出感度の評価 : Evaluation for sensitivity of kinetic macro-parameters estimated in [18F]FDOPA PET study to changes in dopamine matabolism.; [18F] FDOPA PET ドウタイカイセキデスイテイサレタパラメータノドーパミンタイシャノヘンカニタイスルケンシュツカンドノヒョウカ. (Thesis). Nara Institute of Science and Technology / 奈良先端科学技術大学院大学. Retrieved from http://hdl.handle.net/10061/5551

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

松原, 佳亮. “[18F]FDOPA PET動態解析で推定されたパラメータのドーパミン代謝の変化に対する検出感度の評価 : Evaluation for sensitivity of kinetic macro-parameters estimated in [18F]FDOPA PET study to changes in dopamine matabolism.; [18F] FDOPA PET ドウタイカイセキデスイテイサレタパラメータノドーパミンタイシャノヘンカニタイスルケンシュツカンドノヒョウカ.” Thesis, Nara Institute of Science and Technology / 奈良先端科学技術大学院大学. Accessed January 19, 2021. http://hdl.handle.net/10061/5551.

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

松原, 佳亮. “[18F]FDOPA PET動態解析で推定されたパラメータのドーパミン代謝の変化に対する検出感度の評価 : Evaluation for sensitivity of kinetic macro-parameters estimated in [18F]FDOPA PET study to changes in dopamine matabolism.; [18F] FDOPA PET ドウタイカイセキデスイテイサレタパラメータノドーパミンタイシャノヘンカニタイスルケンシュツカンドノヒョウカ.” Web. 19 Jan 2021.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Vancouver:

松原 �. [18F]FDOPA PET動態解析で推定されたパラメータのドーパミン代謝の変化に対する検出感度の評価 : Evaluation for sensitivity of kinetic macro-parameters estimated in [18F]FDOPA PET study to changes in dopamine matabolism.; [18F] FDOPA PET ドウタイカイセキデスイテイサレタパラメータノドーパミンタイシャノヘンカニタイスルケンシュツカンドノヒョウカ. [Internet] [Thesis]. Nara Institute of Science and Technology / 奈良先端科学技術大学院大学; [cited 2021 Jan 19]. Available from: http://hdl.handle.net/10061/5551.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

Council of Science Editors:

松原 �. [18F]FDOPA PET動態解析で推定されたパラメータのドーパミン代謝の変化に対する検出感度の評価 : Evaluation for sensitivity of kinetic macro-parameters estimated in [18F]FDOPA PET study to changes in dopamine matabolism.; [18F] FDOPA PET ドウタイカイセキデスイテイサレタパラメータノドーパミンタイシャノヘンカニタイスルケンシュツカンドノヒョウカ. [Thesis]. Nara Institute of Science and Technology / 奈良先端科学技術大学院大学; Available from: http://hdl.handle.net/10061/5551

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

14. 高井, 雄紀. PET装置によるアミロイドβの無採血定量診断の検討 : Study of non-blood sampling quantitative diagnosis of amyloid β by the PET; PET ソウチニヨルアミロイド β ノムサイケツテイリョウシンダンノケントウ.

Degree: Nara Institute of Science and Technology / 奈良先端科学技術大学院大学

URL: http://hdl.handle.net/10061/9405

Subjects/Keywords: PET

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APA (6^th Edition):

高井, �. (n.d.). PET装置によるアミロイドβの無採血定量診断の検討 : Study of non-blood sampling quantitative diagnosis of amyloid β by the PET; PET ソウチニヨルアミロイド β ノムサイケツテイリョウシンダンノケントウ. (Thesis). Nara Institute of Science and Technology / 奈良先端科学技術大学院大学. Retrieved from http://hdl.handle.net/10061/9405

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

高井, 雄紀. “PET装置によるアミロイドβの無採血定量診断の検討 : Study of non-blood sampling quantitative diagnosis of amyloid β by the PET; PET ソウチニヨルアミロイド β ノムサイケツテイリョウシンダンノケントウ.” Thesis, Nara Institute of Science and Technology / 奈良先端科学技術大学院大学. Accessed January 19, 2021. http://hdl.handle.net/10061/9405.

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

高井, 雄紀. “PET装置によるアミロイドβの無採血定量診断の検討 : Study of non-blood sampling quantitative diagnosis of amyloid β by the PET; PET ソウチニヨルアミロイド β ノムサイケツテイリョウシンダンノケントウ.” Web. 19 Jan 2021.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Vancouver:

高井 �. PET装置によるアミロイドβの無採血定量診断の検討 : Study of non-blood sampling quantitative diagnosis of amyloid β by the PET; PET ソウチニヨルアミロイド β ノムサイケツテイリョウシンダンノケントウ. [Internet] [Thesis]. Nara Institute of Science and Technology / 奈良先端科学技術大学院大学; [cited 2021 Jan 19]. Available from: http://hdl.handle.net/10061/9405.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

Council of Science Editors:

高井 �. PET装置によるアミロイドβの無採血定量診断の検討 : Study of non-blood sampling quantitative diagnosis of amyloid β by the PET; PET ソウチニヨルアミロイド β ノムサイケツテイリョウシンダンノケントウ. [Thesis]. Nara Institute of Science and Technology / 奈良先端科学技術大学院大学; Available from: http://hdl.handle.net/10061/9405

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

Oregon State University

15. Srivastava, Aarushi. Investigating the Effect of Tetrahydrofuran (THF) Plasticizer on the Crystallization and Solvent Seaming of PET/NPG Copolymer Films.

Degree: MS, Chemical Engineering, 2017, Oregon State University

URL: http://hdl.handle.net/1957/60621

► Polyethylene terephthalate (PET) polymer has been the material of choice for packaging industry as a result of its excellent mechanical and physical properties. These properties… (more)

Subjects/Keywords: PET; Tetrahydrofuran

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APA (6^th Edition):

Srivastava, A. (2017). Investigating the Effect of Tetrahydrofuran (THF) Plasticizer on the Crystallization and Solvent Seaming of PET/NPG Copolymer Films. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/60621

Chicago Manual of Style (16^th Edition):

Srivastava, Aarushi. “Investigating the Effect of Tetrahydrofuran (THF) Plasticizer on the Crystallization and Solvent Seaming of PET/NPG Copolymer Films.” 2017. Masters Thesis, Oregon State University. Accessed January 19, 2021. http://hdl.handle.net/1957/60621.

MLA Handbook (7^th Edition):

Srivastava, Aarushi. “Investigating the Effect of Tetrahydrofuran (THF) Plasticizer on the Crystallization and Solvent Seaming of PET/NPG Copolymer Films.” 2017. Web. 19 Jan 2021.

Vancouver:

Srivastava A. Investigating the Effect of Tetrahydrofuran (THF) Plasticizer on the Crystallization and Solvent Seaming of PET/NPG Copolymer Films. [Internet] [Masters thesis]. Oregon State University; 2017. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/1957/60621.

Council of Science Editors:

Srivastava A. Investigating the Effect of Tetrahydrofuran (THF) Plasticizer on the Crystallization and Solvent Seaming of PET/NPG Copolymer Films. [Masters Thesis]. Oregon State University; 2017. Available from: http://hdl.handle.net/1957/60621

University of Michigan

16. Putorti, Anthony Demetrio, Jr. Simultaneous measurements of drop size and velocity in large-scale sprinkler flows using particle tracking and laser -induced fluorescence.

Degree: PhD, Mechanical engineering, 2004, University of Michigan

URL: http://hdl.handle.net/2027.42/124164

► Automatic fire sprinkler systems greatly reduce fire losses and deaths. While sprinklers provide an estimated 75% reduction in death rate within residential structures, they are… (more)

▼ Automatic fire sprinkler systems greatly reduce fire losses and deaths. While sprinklers provide an estimated 75% reduction in death rate within residential structures, they are installed in less than 2% of new U.S. homes. A major impediment is sprinkler system cost, which can be reduced by optimization of the water flux distribution to the burning surfaces. If sprinkler drop size and velocity distributions are known, water flux distributions can be predicted. Existing measurement techniques, however, are incapable of large scale simultaneous measurement of droplet size and velocity, and cannot operate in fire environments. The Particle Tracking Velocimetry and Imaging (PTVI) technique was developed to provide large-scale, simultaneous, non-intrusive measurement of droplet size and velocity in two phase flows. The apparatus illuminates a 0.5 m by 0.5 m region of the spray field with two consecutive laser sheet pulses of different wavelengths. Dyes in the water fluoresce in two different colors, resulting in two differentiable color images for each drop, which are recorded by a camera. Drop velocity is determined from the distance traveled in the time between the pulses, and size from the areas of the droplet images. Droplet sizes from 200 mum to 3000 mum, and velocities from 1 m/s to 30 m/s have been measured with low uncertainty. While not studied here, the PTVI technique is general enough to measure many types of two-phase flows, such as those that occur in fire environments, engines, and manufacturing processes. Droplet sizes and velocities from axis-symmetrical sprinkler sprays were measured using the PTVI technique. Water flux distributions on the floor under the sprinkler were calculated using droplet trajectories, and agreed with measured water fluxes when entrainment could be neglected. Agreement also occurred when the droplets were assumed to start at the sprinkler and at the speed of the water exiting the sprinkler, suggesting that the sheet breakup region and mechanism can be ignored. Scaling parameters are suggested for droplet trajectory analysis. These developments simplify the prediction of water flux distribution and allow for the changing of sprinkler parameters to produce desired water distributions. Advisors/Committee Members: Atreya, Arvind (advisor).

Subjects/Keywords: Drop Size; Large; Laser-induced Fluorescence; Particle Tracking; Scale; Simultaneous Measurements; Sprinkler Flows; Using; Velocity

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APA (6^th Edition):

Putorti, Anthony Demetrio, J. (2004). Simultaneous measurements of drop size and velocity in large-scale sprinkler flows using particle tracking and laser -induced fluorescence. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/124164

Chicago Manual of Style (16^th Edition):

Putorti, Anthony Demetrio, Jr. “Simultaneous measurements of drop size and velocity in large-scale sprinkler flows using particle tracking and laser -induced fluorescence.” 2004. Doctoral Dissertation, University of Michigan. Accessed January 19, 2021. http://hdl.handle.net/2027.42/124164.

MLA Handbook (7^th Edition):

Putorti, Anthony Demetrio, Jr. “Simultaneous measurements of drop size and velocity in large-scale sprinkler flows using particle tracking and laser -induced fluorescence.” 2004. Web. 19 Jan 2021.

Vancouver:

Putorti, Anthony Demetrio J. Simultaneous measurements of drop size and velocity in large-scale sprinkler flows using particle tracking and laser -induced fluorescence. [Internet] [Doctoral dissertation]. University of Michigan; 2004. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/2027.42/124164.

Council of Science Editors:

Putorti, Anthony Demetrio J. Simultaneous measurements of drop size and velocity in large-scale sprinkler flows using particle tracking and laser -induced fluorescence. [Doctoral Dissertation]. University of Michigan; 2004. Available from: http://hdl.handle.net/2027.42/124164

University of Michigan

17. Indiresan, Rohini Sarpeshkar. Study of equatorial ionospheric irregularities using space tethered, multipoint technique and coordinated ground-based FPI and scintillation measurements.

Degree: PhD, Pure Sciences, 2002, University of Michigan

URL: http://hdl.handle.net/2027.42/129677

► Technological advances are exploiting the Earth's ionosphere for the purpose of communication and navigation spurring a need to understand the ionospheric irregularities which can have… (more)

▼ Technological advances are exploiting the Earth's ionosphere for the purpose of communication and navigation spurring a need to understand the ionospheric irregularities which can have adverse effects on these signals. This dissertation studies equatorial spread F (ESF) irregularities using two different measurement techniques, namely, space-based simultaneous, multi-point measurements and ground-based Fabry-Perot Interferometric (FPI) and scintillation measurements. The TSS-1R mission (1996) provided a novel technique for probing the ionosphere using multiple space tethered sensors to simultaneously sample the ionosphere in the horizontal and vertical scales. Studies using data from this mission indicate that ESF irregularities can have very complex structures with sharp gradients and structuring over vertical scale lengths of the order of 10 km, at 300 km altitude. Large eastward tilt of 55° over this altitudinal scale was observed. Thus, the study has not only provided the first ever simultaneous, in situ, multi-point measurements of ESF morphology, but has also demonstrated the feasibility and potential of using space tethered sensors, flying in formation, to explore irregularities in a two dimensional space scale. Low-latitude, coordinated studies using FPI neutral wind data and ionospheric scintillation measurements from Chile between July – October, 1997, examined the extent of plasma-neutral coupling in the nighttime ionosphere. A correlation between zonal wind characteristics and the occurrence/intensity of spread F was observed. A modest dependence was seen between the meridional winds and spread F. A very high degree of coupling existed between the monthly-averaged zonal winds and irregularity drifts, especially after 2100 LT, suggesting that the F region polarization electric fields are well developed. This provided experimental confirmation of the role of the F region dynamo as the primary driver of the nighttime electrodynamics. Comparison of this study with data from two near-magnetic equatorial sites in Peru showed the existence of latitudinal coherence in plasma-neutral coupling. Thus, the localized winds can exert a strong control over the field-aligned irregularity drifts over at least 7°. The wind and scintillation drift velocities were seen to be higher in Peru, as expected. Simple modeling studies for the Chilean site have been performed for comparison with the experimental results. Advisors/Committee Members: Gilchrist, Brian E. (advisor), Niciejewski, Rick J. (advisor).

Subjects/Keywords: Based; Coordinated; Equatorial; Fpi; Ground; Ionospheric; Irregularities; Measurements; Multipoint; Scintillation; Space Tethered; Spread F; Study; Technique; Using

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Indiresan, R. S. (2002). Study of equatorial ionospheric irregularities using space tethered, multipoint technique and coordinated ground-based FPI and scintillation measurements. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/129677

Chicago Manual of Style (16^th Edition):

Indiresan, Rohini Sarpeshkar. “Study of equatorial ionospheric irregularities using space tethered, multipoint technique and coordinated ground-based FPI and scintillation measurements.” 2002. Doctoral Dissertation, University of Michigan. Accessed January 19, 2021. http://hdl.handle.net/2027.42/129677.

MLA Handbook (7^th Edition):

Indiresan, Rohini Sarpeshkar. “Study of equatorial ionospheric irregularities using space tethered, multipoint technique and coordinated ground-based FPI and scintillation measurements.” 2002. Web. 19 Jan 2021.

Vancouver:

Indiresan RS. Study of equatorial ionospheric irregularities using space tethered, multipoint technique and coordinated ground-based FPI and scintillation measurements. [Internet] [Doctoral dissertation]. University of Michigan; 2002. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/2027.42/129677.

Council of Science Editors:

Indiresan RS. Study of equatorial ionospheric irregularities using space tethered, multipoint technique and coordinated ground-based FPI and scintillation measurements. [Doctoral Dissertation]. University of Michigan; 2002. Available from: http://hdl.handle.net/2027.42/129677

University of Michigan

18. Yu, Eileen Yi-iun. Structural characterizations of the manganese cluster in the oxygen-evolving complex of photosystem II using electron paramagnetic resonance, x-ray absorption and x-ray standing wave measurements.

Degree: PhD, Pure Sciences, 1999, University of Michigan

URL: http://hdl.handle.net/2027.42/131826

► The oxygen-evolving complex (OEC) in Photosystem II (PSII) is a metalcontaining group of proteins that catalyzes the oxidation of water to oxygen, a function that… (more)

▼ The oxygen-evolving complex (OEC) in Photosystem II (PSII) is a metalcontaining group of proteins that catalyzes the oxidation of water to oxygen, a function that is indispensable to life itself. <display-math> <fd> 2H2O+4phot ons→O2+4H++4 e- </fd> </display-math> At the heart of the OEC is a cluster of four manganese atoms which, together with Ca²⁺ and Cl^- cofactors, have been found to be the inorganic components essential for oxygen production. The objective of the work described in this thesis has been to characterize the structure of the inorganic cofactors responsible for oxygen evolution. The first part of the thesis describes research on elucidation of the functional role of the cofactor Cl^- in the process of water oxidation. Both XAS and EPR characterizations were performed to examine the effects of F^- inhibition on the OEC. In contrast with other reports in the literature, fluoride was found to cause a significant, but reversible, change in the x-ray absorption near edge structure (XANES). This is interpreted as evidence for a change in the oxidation states of the Mn ions when fluoride was added. In agreement with previous reports, fluoride was found to inhibit oxygen evolution. However, careful examination of the kinetics of oxygen evolution showed that fluoride inhibition is turnover-dependent, with significantly greater inhibition after several turnovers. The fluoride concentration that gives half-maximal inhibition (10 mM) is the same as the fluoride concentration that gives half-maximal conversion between the multiline and the g = 4.1 forms of the S₂ EPR signal. The fluoride-induced XANES shift shows similar concentration dependence. Identical spectroscopic changes were observed in the presence or absence of the 17 and 23 kDa extrinsic polypeptides. However, the turnover dependence of fluoride inhibition was only observed in the presence of the extrinsic polypeptides. Variable-period x-ray standing wave (XSW) spectroscopy was used to investigate the relative placement of the inorganic cofactors within the PSII membrane. Oriented monolayer samples were prepared on Au coated mirrors using a mild-etching protocol. Using relatively short incubation times (<10 h), it was possible to obtain an average protein thickness of one monolayer, as determined by ellipsometry measurements. A Peltier-cooled sample stage was designed and constructed to permit XSW measurements at < 0°C. Using this stage, radiation induced sample decomposition could be prevented, as determined by monolayer XANES measurements. Preliminary XSW results indicate that the Mn cluster is located at approximately 27A from the lumenal side of the polypeptide complex. Advisors/Committee Members: Penner-Hahn, James E. (advisor), Yocum, Charles F. (advisor).

Subjects/Keywords: Absorption; Characterizations; Cluster; Electron; Manganese; Measurements; Oxygen-evolving Complex; Paramagnetic; Photosystem Ii; Ray; Resonance; Standing; Structural; Using; Wave

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APA (6^th Edition):

Yu, E. Y. (1999). Structural characterizations of the manganese cluster in the oxygen-evolving complex of photosystem II using electron paramagnetic resonance, x-ray absorption and x-ray standing wave measurements. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/131826

Chicago Manual of Style (16^th Edition):

Yu, Eileen Yi-iun. “Structural characterizations of the manganese cluster in the oxygen-evolving complex of photosystem II using electron paramagnetic resonance, x-ray absorption and x-ray standing wave measurements.” 1999. Doctoral Dissertation, University of Michigan. Accessed January 19, 2021. http://hdl.handle.net/2027.42/131826.

MLA Handbook (7^th Edition):

Yu, Eileen Yi-iun. “Structural characterizations of the manganese cluster in the oxygen-evolving complex of photosystem II using electron paramagnetic resonance, x-ray absorption and x-ray standing wave measurements.” 1999. Web. 19 Jan 2021.

Vancouver:

Yu EY. Structural characterizations of the manganese cluster in the oxygen-evolving complex of photosystem II using electron paramagnetic resonance, x-ray absorption and x-ray standing wave measurements. [Internet] [Doctoral dissertation]. University of Michigan; 1999. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/2027.42/131826.

Council of Science Editors:

Yu EY. Structural characterizations of the manganese cluster in the oxygen-evolving complex of photosystem II using electron paramagnetic resonance, x-ray absorption and x-ray standing wave measurements. [Doctoral Dissertation]. University of Michigan; 1999. Available from: http://hdl.handle.net/2027.42/131826

Siauliai University

19. Tamošauskas, Aurimas. DFM (Design for Manufacturability) metodo taikymas gaminiams iš plastiko gaminti.

Degree: Master, Mechanical Engineering, 2008, Siauliai University

URL: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2008~D_20080929_135929-29173 ;

►

Šis ištirtas DFM metodas padeda atkreipti projektuotojų dėmesį į tas presuojamojo liejimo formavimo ypatybes, kurios yra linkusios didinti gaminio apdirbimo sąnaudas. Tyrime naudojame „šešių laipsnių… (more)

▼

Šis ištirtas DFM metodas padeda atkreipti projektuotojų dėmesį į tas presuojamojo liejimo formavimo ypatybes, kurios yra linkusios didinti gaminio apdirbimo sąnaudas. Tyrime naudojame „šešių laipsnių koduojančia sistema“ tam, kad nustatyti galutines preliminarias ruošinio apdirbimo sąnaudas. Čia pabrėžiamos tos ypatybes, kurios žymiai didina kainą, kad projektuotojai galėtų sumažinti gaminamos detalės sudėtingumą. Naudojant pristatytą metodologiją, projektuotojai gali įvykdyti ruošinių apdirbimo sąnaudų įvertinimą ankstyvojoje konstravimo stadijoje. Tai gali būti įvikdyta pasitelkiant jų apytiksle vieta ir orientacija. Išsamūs matmenys nėra būtini. Metodologija parodo tai, ką detalių charakteristikos įtakoja kainai, kad pagerintų perkonstruotą detalę.

The master’s thesis present the rewiew of design manufacture method. Mechanical part design plays an important role whether company will succeed in market or will fail. From my point of view there are three main measures of the DFM (Design For Manufacture) process: cost, quality and time, which are pivotal in design process. Regardless of the product being designed – whether it is an entire system or some small subpart of a larger product - the customer and management always want it cheaper, better and faster. In this project has described a systematic approach for calling designers attention to those features of injection molding that tend to increase the tooling cost to manufacture parts – and for estimating the relative costs of tooling. The system employs a six – digit coding system for determining total relative tooling cost, which groups parts according to their similarity in tool construction difficulty. The system highlight those features that significantly increase cost so that designers can minimize difficult – to – produce features.

Advisors/Committee Members: Bargelis, Algirdas (Master’s degree committee member), Šniuolis, Raimondas (Master’s degree session secretary), Bareišis, Jonas (Master’s degree committee chair), Bražėnas, Algis (Master’s degree committee member), Ulozas, Ričardas Viktoras (Master’s degree committee member), Bargelis, Algirdas (Master’s thesis supervisor), Šniuolis, Raimondas (Master’s thesis reviewer).

Subjects/Keywords: Dfm; Pet; Dfx; DFM; DFX; PET

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APA (6^th Edition):

Tamošauskas, Aurimas. (2008). DFM (Design for Manufacturability) metodo taikymas gaminiams iš plastiko gaminti. (Masters Thesis). Siauliai University. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2008~D_20080929_135929-29173 ;

Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete

Chicago Manual of Style (16^th Edition):

Tamošauskas, Aurimas. “DFM (Design for Manufacturability) metodo taikymas gaminiams iš plastiko gaminti.” 2008. Masters Thesis, Siauliai University. Accessed January 19, 2021. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2008~D_20080929_135929-29173 ;.

Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete

MLA Handbook (7^th Edition):

Tamošauskas, Aurimas. “DFM (Design for Manufacturability) metodo taikymas gaminiams iš plastiko gaminti.” 2008. Web. 19 Jan 2021.

Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete

Vancouver:

Tamošauskas, Aurimas. DFM (Design for Manufacturability) metodo taikymas gaminiams iš plastiko gaminti. [Internet] [Masters thesis]. Siauliai University; 2008. [cited 2021 Jan 19]. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2008~D_20080929_135929-29173 ;.

Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete

Council of Science Editors:

Tamošauskas, Aurimas. DFM (Design for Manufacturability) metodo taikymas gaminiams iš plastiko gaminti. [Masters Thesis]. Siauliai University; 2008. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2008~D_20080929_135929-29173 ;

Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete

University of Minnesota

20. Fox, Kimberly. Anatomy of a Pet Food Recall: An Industry, Regulatory, and Consumer Perspective.

Degree: MS, Food Science, 2020, University of Minnesota

URL: http://hdl.handle.net/11299/216770

► Abstract Recent, high-profile outbreaks of Salmonellosis infections and recalls associated with pet food and treats are indicative of an industry facing daunting challenges. Consumer demands… (more)

Subjects/Keywords: pet food recalls; pet food safety

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APA (6^th Edition):

Fox, K. (2020). Anatomy of a Pet Food Recall: An Industry, Regulatory, and Consumer Perspective. (Masters Thesis). University of Minnesota. Retrieved from http://hdl.handle.net/11299/216770

Chicago Manual of Style (16^th Edition):

Fox, Kimberly. “Anatomy of a Pet Food Recall: An Industry, Regulatory, and Consumer Perspective.” 2020. Masters Thesis, University of Minnesota. Accessed January 19, 2021. http://hdl.handle.net/11299/216770.

MLA Handbook (7^th Edition):

Fox, Kimberly. “Anatomy of a Pet Food Recall: An Industry, Regulatory, and Consumer Perspective.” 2020. Web. 19 Jan 2021.

Vancouver:

Fox K. Anatomy of a Pet Food Recall: An Industry, Regulatory, and Consumer Perspective. [Internet] [Masters thesis]. University of Minnesota; 2020. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/11299/216770.

Council of Science Editors:

Fox K. Anatomy of a Pet Food Recall: An Industry, Regulatory, and Consumer Perspective. [Masters Thesis]. University of Minnesota; 2020. Available from: http://hdl.handle.net/11299/216770

Universitat de Valencia

21. Aguilar Talens, Albert. Estudio, diseño e integración de un sistema basado en FPGA para el cálculo del tiempo de vuelo aplicado a equipos PET .

Degree: 2014, Universitat de Valencia

URL: http://hdl.handle.net/10550/36214

► La Medicina Nuclear ha experimentado avances significativos en los últimos años debido a la mejora en materiales, sistemas electrónicos, técnicas de algoritmia, de procesado etc.,… (more)

▼ La Medicina Nuclear ha experimentado avances significativos en los últimos años debido a la mejora en materiales, sistemas electrónicos, técnicas de algoritmia, de procesado etc., que han permitido que su aplicación se haya extendido considerablemente. Una de las técnicas que más ha progresado en este ámbito ha sido la Tomografía por Emisión de Positrones (PET, del inglés Positron Emission Tomography), consistente en un método no invasivo y muy útil para la evaluación de anomalías de tipo cancerosas. Este sistema está basado en un principio de toma de datos y procesado mediante el cual se obtienen imágenes de la distribución espacial y temporal de los procesos metabólicos que se generan en el interior del organismo. Los sistemas PET están formados por un conjunto de detectores, colocados habitualmente en anillo, de forma que cada uno de ellos proporciona información acerca de los eventos que se han producido en su interior. Uno de los motivos por el cual los sistemas PET han evolucionado de forma tan significativa, ha sido la aparición de técnicas que permiten determinar el Tiempo de Vuelo (TOF, del inglés Time of Flight) de los fotones que se generan a causa de la aniquilación de los positrones con su antipartícula, los electrones. La determinación del TOF permite establecer con mayor precisión la ubicación de los eventos que se generan y, por tanto, facilita la labor de reconstrucción de la imagen que, en última instancia, utilizará el equipo médico para el diagnóstico y/o tratamiento. En esta Tesis se parte de la hipótesis de desarrollar un sistema basado en Dispositivos Lógicos Reconfigurables (FPGAs, del inglés Field Programmable Gate Arrays) para la integración de un Convertidor Digital de Tiempo (TDC, del inglés Time-to-Digital Converter) para la medida precisa de tiempos con capacidad para el cálculo de la diferencia temporal de las partículas gamma para su posterior aplicación en sistemas PET. Inicialmente, se describe el entorno dentro del cual surge la necesidad de la implementación de tal sistema y se formula una premisa de partida. A continuación, se exponen los principios básicos del PET así como el estado del arte de los sistemas similares. Seguidamente, se plantean los principios del cálculo del TOF con FPGAs y se justifica el esquema adoptado, entrando en detalle en cada una de sus partes. Tras la implementación, se presentan los primeros resultados de medida de tiempos, obteniendo resoluciones menores de 100 ps para múltiples canales y caracterizando el sistema ante variaciones de temperatura. Una vez caracterizado el sistema, se presentan las pruebas realizadas con un prototipo PET de mama y con tecnología de detectores FotoMultiplicadores Sensibles a la Posición (PSPMTs, del inglés, Position Sensitive PhotoMultiplier Tubes), haciendo medidas de TOF para distintos supuestos. Tras esta primera prueba, se pasa a la implementación de dos módulos de FotoMultiplicadores basados en Silicio (SiPMs, del inglés Silicon PhotoMultipliers), detectores que presentan con respecto a los PSPMTs, entre otras… Advisors/Committee Members: Torres País, José (advisor).

Subjects/Keywords: tof; fpga; pet

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APA (6^th Edition):

Aguilar Talens, A. (2014). Estudio, diseño e integración de un sistema basado en FPGA para el cálculo del tiempo de vuelo aplicado a equipos PET . (Doctoral Dissertation). Universitat de Valencia. Retrieved from http://hdl.handle.net/10550/36214

Chicago Manual of Style (16^th Edition):

Aguilar Talens, Albert. “Estudio, diseño e integración de un sistema basado en FPGA para el cálculo del tiempo de vuelo aplicado a equipos PET .” 2014. Doctoral Dissertation, Universitat de Valencia. Accessed January 19, 2021. http://hdl.handle.net/10550/36214.

MLA Handbook (7^th Edition):

Aguilar Talens, Albert. “Estudio, diseño e integración de un sistema basado en FPGA para el cálculo del tiempo de vuelo aplicado a equipos PET .” 2014. Web. 19 Jan 2021.

Vancouver:

Aguilar Talens A. Estudio, diseño e integración de un sistema basado en FPGA para el cálculo del tiempo de vuelo aplicado a equipos PET . [Internet] [Doctoral dissertation]. Universitat de Valencia; 2014. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/10550/36214.

Council of Science Editors:

Aguilar Talens A. Estudio, diseño e integración de un sistema basado en FPGA para el cálculo del tiempo de vuelo aplicado a equipos PET . [Doctoral Dissertation]. Universitat de Valencia; 2014. Available from: http://hdl.handle.net/10550/36214

22. Jissendi Tchofo, Patrice. Les dysplasies cérébelleuses : corrélations anatomo-fonctionnelles : Cerebellar dysplasias : structural functional correlations.

Degree: Docteur es, Radiologie et imagerie médecine, 2011, Université Lille II – Droit et Santé

URL: http://www.theses.fr/2011LIL2S006

► La dysplasie cérébelleuse est une anomalie du développement tissulaire intéressant principalement le cervelet et résultant en une anomalie focale ou diffuse de son architecture macroscopique… (more)

▼ La dysplasie cérébelleuse est une anomalie du développement tissulaire intéressant principalement le cervelet et résultant en une anomalie focale ou diffuse de son architecture macroscopique et microscopique. Plusieurs travaux antérieurs ont bien documenté sa caractérisation morphologique à l'imagerie par résonance magnétique (IRM). Cependant, le retentissement de cette malformation, parfois associée à d'autres anomalies développementales du système nerveux central (SNC), sur le développement et le fonctionnement cognitifs est mal connu et peu documenté. Dans le but d'étudier les corrélations anatomo-fonctionnelles de cette pathologie constitutionnelle du cervelet, par le biais de l'approche des altérations neuropsychologiques, génétiques et, fonctionnelles associées, ainsi que par l'approche neuroanatomique, nous avons dirigé nos travaux dans quatre axes principaux et sur trois types de population distinctes. Le premier axe a concerné l'évaluation du profil neuropsychologique et du suivi chez dix enfants porteurs d'une dysplasie cérébelleuse isolée (DCI). Nous avons pu observer chez ces enfants une grande diversité de l'expression neuropsychologique de la DCI, depuis l'efficience normale jusqu'au retard mental sévère, sans corrélation avec le degré de dysplasie. D'autre part, au cours du suivi de ces enfants, nous avons observé une hétérogénéité d'évolution à caractère imprédictible, avec l'émergence des certaines fonctions dans l'axe du langage notamment. Le deuxième axe a porté sur l'investigation fonctionnelle du SNC par l'étude de la consommation cérébrale du fluorodeoxyglucose par Tomographie à émission de positons (TEP-FDG) chez six enfants porteurs d'une DCI. Les résultats ont montré, au sein du cervelet, un aspect normal dans les dysplasies mineures (limitées au vermis), un hypométabolisme des zones dysplasiques (corrélé à l'extension anatomique), et un isométabolisme au cortex dans les hétérotopies. Toutefois, ces anomalies de captation du glucose n'étaient pas corrélées au dysfonctionnement cognitif. Le troisième axe était d'approcher les corrélations génétiques, dans l'hypothèse d'un lien physiopathologique embryologique entre le cerveau et le cervelet, dans les dysplasies cérébelleuses associées (DCA) aux Lissencéphalies (cerveaux lisses). La caractérisation génétique relativement bien définie des Lissencéphalies nous a permis d'identifier des gènes de la migration neuronale et axonale (RELN et VLDRL) comme étant significativement associés aux dysplasies cérébelleuses, en dehors des dystrophies musculaires congénitales impliquant les gènes de la O-glycosylation. Le quatrième axe a été de rechercher chez des volontaires sains les marqueurs neuroanatomiques potentiels des altérations cognitives dans les dysplasies cérébelleuses, partant de l'hypothèse selon laquelle, une malformation isolée du cervelet induirait des anomalies anatomiques détectables en imagerie par tenseur de diffusion (DTI), sur les voies de projections cérébello-corticales, vraisemblablement impliquées dans la contribution du cervelet au… Advisors/Committee Members: Vinchon, Mathieu (thesis director).

Subjects/Keywords: TEP; Pet-Scan

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APA (6^th Edition):

Jissendi Tchofo, P. (2011). Les dysplasies cérébelleuses : corrélations anatomo-fonctionnelles : Cerebellar dysplasias : structural functional correlations. (Doctoral Dissertation). Université Lille II – Droit et Santé. Retrieved from http://www.theses.fr/2011LIL2S006

Chicago Manual of Style (16^th Edition):

Jissendi Tchofo, Patrice. “Les dysplasies cérébelleuses : corrélations anatomo-fonctionnelles : Cerebellar dysplasias : structural functional correlations.” 2011. Doctoral Dissertation, Université Lille II – Droit et Santé. Accessed January 19, 2021. http://www.theses.fr/2011LIL2S006.

MLA Handbook (7^th Edition):

Jissendi Tchofo, Patrice. “Les dysplasies cérébelleuses : corrélations anatomo-fonctionnelles : Cerebellar dysplasias : structural functional correlations.” 2011. Web. 19 Jan 2021.

Vancouver:

Jissendi Tchofo P. Les dysplasies cérébelleuses : corrélations anatomo-fonctionnelles : Cerebellar dysplasias : structural functional correlations. [Internet] [Doctoral dissertation]. Université Lille II – Droit et Santé 2011. [cited 2021 Jan 19]. Available from: http://www.theses.fr/2011LIL2S006.

Council of Science Editors:

Jissendi Tchofo P. Les dysplasies cérébelleuses : corrélations anatomo-fonctionnelles : Cerebellar dysplasias : structural functional correlations. [Doctoral Dissertation]. Université Lille II – Droit et Santé 2011. Available from: http://www.theses.fr/2011LIL2S006

Colorado State University

23. Forrest, Marielle. Othering of pets: Palmer, Plumwood, and pet technology ethics, The.

Degree: MA, Philosophy, 2019, Colorado State University

URL: http://hdl.handle.net/10217/197338

► In Chapter 1, I explore some of the central theories in the field of animal ethics, those by: Peter Singer, Tom Regan, Martha Nussbaum, and… (more)

Subjects/Keywords: animal ethics; pet ethics; pet technology; othering; ACI; pet-keeping

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APA (6^th Edition):

Forrest, M. (2019). Othering of pets: Palmer, Plumwood, and pet technology ethics, The. (Masters Thesis). Colorado State University. Retrieved from http://hdl.handle.net/10217/197338

Chicago Manual of Style (16^th Edition):

Forrest, Marielle. “Othering of pets: Palmer, Plumwood, and pet technology ethics, The.” 2019. Masters Thesis, Colorado State University. Accessed January 19, 2021. http://hdl.handle.net/10217/197338.

MLA Handbook (7^th Edition):

Forrest, Marielle. “Othering of pets: Palmer, Plumwood, and pet technology ethics, The.” 2019. Web. 19 Jan 2021.

Vancouver:

Forrest M. Othering of pets: Palmer, Plumwood, and pet technology ethics, The. [Internet] [Masters thesis]. Colorado State University; 2019. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/10217/197338.

Council of Science Editors:

Forrest M. Othering of pets: Palmer, Plumwood, and pet technology ethics, The. [Masters Thesis]. Colorado State University; 2019. Available from: http://hdl.handle.net/10217/197338

Kansas State University

24. Tsai, Wei-Lun. Understanding pet food consumers with various sensory analysis methods.

Degree: MS, Food Science Institute, 2019, Kansas State University

URL: http://hdl.handle.net/2097/40047

► The pet food industry has been fast-growing over the past decades, which makes the pet food market very competitive. Understanding pet food consumers plays an… (more)

▼ The pet food industry has been fast-growing over the past decades, which makes the pet food market very competitive. Understanding pet food consumers plays an important role in this competition to investigate purchase decisions. There are two aspects of pet food consumers, which includes pets that consume products, and pet owners who buy products. This research focused on two factors, palatability and emotion, that may affect purchase decisions from the perspectives of pet and pet owner. The objective of the first study was to investigate dog preference for various meats using the preference ranking test. Twelve beagle dogs performed the preference ranking procedure to rank five different meats: beef, chicken, lamb, pork, and turkey. Dog preference for cooked and raw meats were both tested during the study. In addition, a descriptive analysis of cooked meat aroma characteristics was conducted with four highly trained panelists to profile the meats. The results showed that dog preference for cooked and raw meats was similar, in which beef was preferred over chicken and pork. Specific cooked meat aroma characteristics such as meaty overall and brown/roasted might be intrinsic drivers of liking in dogs. The goals of the second study were to generate emotion terminology from both pets and pet owners and to investigate body languages and signs perceived by pet owners related to pet emotion. Four focus group sessions were conducted to gather insights from pet owners according to emotions they and their pets experienced. Lists of 38 and 55 emotion terms were generated for dogs and cats, respectively. In addition, lists of 33 and 62 emotion terms were created for dog owners and cat owners, respectively. Examples of emotion terms generated for pets and pet owners included excited, happy, anxious, and fearful. The validation of these emotion terms was conducted in the third study. The objective of the third study was to understand consumer (dog and dog owner) acceptance of granola-bar-like dog treats made with various sources of crisp and binder. Fifteen different kinds of treats were baked with three sources of crisp (rice crisp, white sorghum crisp, and red sorghum crisp) and five sources of binder (corn syrup, spray dried plasma, gelatin, albumin, and egg white). A home-use-test was conducted with 39 dog owners and their pets to evaluate the treats for overall liking, dog’s liking, appearance, aroma, and texture. In addition, emotion terms were probed during the test. The results showed that there was no significant difference for the owner’s overall liking and the dog’s liking among the treats. Positive emotions such as content/satisfied and happy were experienced frequently by the owners when dogs consumed the treats. Conversely, dogs were reported excited, happy, and eager when eating the treats. These studies demonstrated that a combination of palatability test and sensory analysis provided insights from both and pet and pet owners, which may be helpful for the pet food industry to understand the pet food consumers… Advisors/Committee Members: Kadri Koppel.

Subjects/Keywords: Palatability Test; Descriptive Analysis; Emotion; Pet; Pet Owner; Pet Food

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Tsai, W. (2019). Understanding pet food consumers with various sensory analysis methods. (Masters Thesis). Kansas State University. Retrieved from http://hdl.handle.net/2097/40047

Chicago Manual of Style (16^th Edition):

Tsai, Wei-Lun. “Understanding pet food consumers with various sensory analysis methods.” 2019. Masters Thesis, Kansas State University. Accessed January 19, 2021. http://hdl.handle.net/2097/40047.

MLA Handbook (7^th Edition):

Tsai, Wei-Lun. “Understanding pet food consumers with various sensory analysis methods.” 2019. Web. 19 Jan 2021.

Vancouver:

Tsai W. Understanding pet food consumers with various sensory analysis methods. [Internet] [Masters thesis]. Kansas State University; 2019. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/2097/40047.

Council of Science Editors:

Tsai W. Understanding pet food consumers with various sensory analysis methods. [Masters Thesis]. Kansas State University; 2019. Available from: http://hdl.handle.net/2097/40047

Addis Ababa University

25. Yonan, Getachew. Design and implementation of Crisis and Emergency Reporting and Response system using SMS .

Degree: 2012, Addis Ababa University

URL: http://etd.aau.edu.et/dspace/handle/123456789/2732

► Effective and reliable communication plays a critical role in helping organization engaged in the area of crisis and emergency reporting and responding. Addis Ababa Police… (more)

▼ Effective and reliable communication plays a critical role in helping organization engaged in the area of crisis and emergency reporting and responding. Addis Ababa Police Commission is an organization working in the area of responding to crisis and emergency related incidents in Addis Ababa. When faced with crises and emergency situations, for the purpose of reporting different type of incident, the general public is limited to using phone calls. Being limited to using phone calls, the Police Commission is facing different difficulties mainly in the credibility of the report, since phone calls are mostly anonymous false and unreliable reports are being received. This affects the action taken to the incident in managing available resource effectively. Therefore there is a need to enhance the communication medium by using an additional means of reporting crises and emergency incidents. The use of mobile technologies are so broadening that people are depending on this technology in their day to day activities to effectively communicate and collaborate with each other whether handling their personal or business activities. One of the features of mobile technologies that have come to be broadly used is SMS (Short messaging Service) which enables the user to send and receive text messages using mobile phones. Different SMS based applications are currently being developed globally by different organizations for different purposes in the business world, health, monitoring, supply chain management etc. After conducting a survey on the current condition of crises and emergency reporting and responding at Addis Ababa Police Commission, and identifying the available current technologies, we have developed a system called MobiRep that can alleviate the problems that is more efficient and economical. MobiRep is a system engaged in accepting reports from any mobile phones using the SMS. In addition to accepting reports, the system can also send SMS or broadcast bulk SMS to a group or multiple devices that can accept text messages. After accepting a report, the police can also use the broadcasting feature of the system to take necessary action to an incident by dispatching resources. Additionally, the system will also be able to send SMS alerts in warning subscribed users about a major incident or criminal activities that occurred or may occur near their neighborhood. Generally the system to be developed will play a good role in being an additional means of accepting real-time reports and also help by filling the communication gap in reporting and responding to a crisis, crime or an emergency. Advisors/Committee Members: Dr. Solomon Atnafu (advisor).

Subjects/Keywords: Response system using SMS

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Yonan, G. (2012). Design and implementation of Crisis and Emergency Reporting and Response system using SMS . (Thesis). Addis Ababa University. Retrieved from http://etd.aau.edu.et/dspace/handle/123456789/2732

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Yonan, Getachew. “Design and implementation of Crisis and Emergency Reporting and Response system using SMS .” 2012. Thesis, Addis Ababa University. Accessed January 19, 2021. http://etd.aau.edu.et/dspace/handle/123456789/2732.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Yonan, Getachew. “Design and implementation of Crisis and Emergency Reporting and Response system using SMS .” 2012. Web. 19 Jan 2021.

Vancouver:

Yonan G. Design and implementation of Crisis and Emergency Reporting and Response system using SMS . [Internet] [Thesis]. Addis Ababa University; 2012. [cited 2021 Jan 19]. Available from: http://etd.aau.edu.et/dspace/handle/123456789/2732.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Yonan G. Design and implementation of Crisis and Emergency Reporting and Response system using SMS . [Thesis]. Addis Ababa University; 2012. Available from: http://etd.aau.edu.et/dspace/handle/123456789/2732

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

26. Pacifico, Antonio Luiz. Análise teórico-experimental do escoamento bifásico no interior de bocais nebulizadores do tipo \"Y - JET\".

Degree: PhD, Engenharia Mecânica, 2000, University of São Paulo

URL: http://www.teses.usp.br/teses/disponiveis/3/3132/tde-27082001-132246/ ;

►

Neste trabalho de pesquisa foram estudados os efeitos dos parâmetros geométricos e de processo nas características do escoamento bifásico no interior de oito bocais nebulizadores… (more)

▼

Neste trabalho de pesquisa foram estudados os efeitos dos parâmetros geométricos e de processo nas características do escoamento bifásico no interior de oito bocais nebulizadores do tipo \"Y-Jetätravés de uma bancada de análise experimental utilizando-se como fluidos de trabalho ar comprimido e água. Os resultados indicaram que as vazões mássicas são altamente dependentes da pressão de suprimento de ar e da relação entre os diâmetros do duto de mistura e do bocal de alimentação de ar. Em muitas situações de operação, esses dispositivos nebulizadores operavam com o escoamento de ar blocado à saída do seu bocal de alimentação. Outro aspecto importante é que, devido a fortes irreversibilidades inerentes ao padrão de escoamento, a expansão do fluxo de ar do seu bocal de alimentação para o duto de mistura aproxima-se muito mais de uma expansão isoentálpica que isoentrópica. Para fluxos mássicos de água superiores a 6000 kg/m2.s a distribuição de pressão no interior do duto de mistura é praticamente linear, independentemente do valor da pressão de alimentação de ar. Uma correlação para a previsão do valor da pressão no ponto de mistura entre os fluxos de ar e água dentro do duto de mistura foi desenvolvida e mostrou-se adequada para valores dentro da faixa de variação de cada parâmetro no experimento. Através de um aparato óptico buscou-se a medição da espessura média local de filme de líquido e da velocidade das perturbações na interface ar/água. Os resultados para a medição da espessura de filme mostraram-se sensivelmente dispersos, apontando para um melhor desenvolvimento dessas técnicas ópticas em futuros trabalhos. Quanto às velocidades das perturbações os resultados indicaram um razoável aumento destas conforme o escoamento se aproxima da saída do duto de mistura. Para todos os oito bocais ensaiados o valor médio destas velocidades, à saída do duto de mistura, situou-se em torno de 60 a 65 m/s. Um modelo teórico-experimental, baseado na medição da queda de pressão no interior do duto de mistura desses bocais, foi desenvolvido. Através desse modelo foi possível prever, localmente, a espessura e a velocidade médias de filme de líquido, a fração de entranhamento, a tensão de cisalhamento na interface ar/água, a fração de vazio e a velocidade média do ar no núcleo do escoamento.

In this research work the effects of the process and geometrical parameters on the characteristics of the internal two-phase flow inside eight Y-Jet atomizers were studied using an apparatus working with air and water. The results show that the flow rates are very dependent on the air supply pressure and the diameter ratio of the mixing duct and the air port. It was also verified that, in many operational conditions, these atomizers worked in the critical condition at the exit of the air port. Due to the strong irreversibilities present in the flow, the expansion from the air port to the mixing duct is closer to an isoenthalpic process than to an isoentropic process. For water mass flux greater than 6000 kg/m2.s, the pressure distribution…

Advisors/Committee Members: Yanagihara, Jurandir Itizo.

Subjects/Keywords: atomização; atomization; bocais nebulizadores ´y-jet´; escoamento bifásico anular; measurements using optical techniques; medição por técnicas ópticas; two-phase annular flow; y-jet atomizers

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Pacifico, A. L. (2000). Análise teórico-experimental do escoamento bifásico no interior de bocais nebulizadores do tipo \"Y - JET\". (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/3/3132/tde-27082001-132246/ ;

Chicago Manual of Style (16^th Edition):

Pacifico, Antonio Luiz. “Análise teórico-experimental do escoamento bifásico no interior de bocais nebulizadores do tipo \"Y - JET\".” 2000. Doctoral Dissertation, University of São Paulo. Accessed January 19, 2021. http://www.teses.usp.br/teses/disponiveis/3/3132/tde-27082001-132246/ ;.

MLA Handbook (7^th Edition):

Pacifico, Antonio Luiz. “Análise teórico-experimental do escoamento bifásico no interior de bocais nebulizadores do tipo \"Y - JET\".” 2000. Web. 19 Jan 2021.

Vancouver:

Pacifico AL. Análise teórico-experimental do escoamento bifásico no interior de bocais nebulizadores do tipo \"Y - JET\". [Internet] [Doctoral dissertation]. University of São Paulo; 2000. [cited 2021 Jan 19]. Available from: http://www.teses.usp.br/teses/disponiveis/3/3132/tde-27082001-132246/ ;.

Council of Science Editors:

Pacifico AL. Análise teórico-experimental do escoamento bifásico no interior de bocais nebulizadores do tipo \"Y - JET\". [Doctoral Dissertation]. University of São Paulo; 2000. Available from: http://www.teses.usp.br/teses/disponiveis/3/3132/tde-27082001-132246/ ;

Vrije Universiteit Amsterdam

27. Sicam, V.A.D.P. Optical properties of the human cornea : Shape and wave aberration measurements using the VU topographer and Scheimpflug photography .

Degree: 2007, Vrije Universiteit Amsterdam

URL: http://hdl.handle.net/1871/10864

► In this study, the optical properties of the human cornea was investigated. Two major developments were made because current measurement techniques need improvement First, the… (more)

Subjects/Keywords: Optical properties of the human cornea: shape and wave aberration measurements using the VU topographer and Scheimplug photography; cornea topography; wave aberation; Scheimpflug photography

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sicam, V. A. D. P. (2007). Optical properties of the human cornea : Shape and wave aberration measurements using the VU topographer and Scheimpflug photography . (Doctoral Dissertation). Vrije Universiteit Amsterdam. Retrieved from http://hdl.handle.net/1871/10864

Chicago Manual of Style (16^th Edition):

Sicam, V A D P. “Optical properties of the human cornea : Shape and wave aberration measurements using the VU topographer and Scheimpflug photography .” 2007. Doctoral Dissertation, Vrije Universiteit Amsterdam. Accessed January 19, 2021. http://hdl.handle.net/1871/10864.

MLA Handbook (7^th Edition):

Sicam, V A D P. “Optical properties of the human cornea : Shape and wave aberration measurements using the VU topographer and Scheimpflug photography .” 2007. Web. 19 Jan 2021.

Vancouver:

Sicam VADP. Optical properties of the human cornea : Shape and wave aberration measurements using the VU topographer and Scheimpflug photography . [Internet] [Doctoral dissertation]. Vrije Universiteit Amsterdam; 2007. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/1871/10864.

Council of Science Editors:

Sicam VADP. Optical properties of the human cornea : Shape and wave aberration measurements using the VU topographer and Scheimpflug photography . [Doctoral Dissertation]. Vrije Universiteit Amsterdam; 2007. Available from: http://hdl.handle.net/1871/10864

28. Psaltis, Antonios. Design and development of a real time bio-sensing system assessing student mental workload and engagement.

Degree: 2018, National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ)

URL: http://hdl.handle.net/10442/hedi/44400

► Facing the challenge of improving adaptive interaction in educational technologies scientists and educators have turned their focal point in diverse areas ranging from educational, teaching… (more)

▼ Facing the challenge of improving adaptive interaction in educational technologies scientists and educators have turned their focal point in diverse areas ranging from educational, teaching and behavioural psychology to cognitive, affective and perceptual neuroscience. The introduction of digital technologies and interactive media tools in education has shown improved learning efficiency, much higher memory activation and assimilation than verbal teaching, notably due to enhancing motivation achieved by employing approaches attracting student’s attention. Excelling aspects of audio visual presentation proved highly valuable particularly in classes with multi ethnic groups of students, as for example consistency between definitions and objects which were verbally and visually defined, eliminating possible misconceptions caused by mishearing or misinterpretation by the learner. Taking it all one step further as to how an educational system could be even more efficient, a new element would be needed revealing a credible judgment of learning scores and effectiveness of the learning process instantaneously as for example inner levels of activation and satisfaction. In fact, this could be made possible using existing technologies if subconscious neurophysiological responses of a learner could be ascertained and inferred to psycho-somatic conditions as they occur. A system including bio-sensing, data analysis and processing in real time able to provide quantified markers of psychosomatic states of a learner would help enormously in next generations of educational practice. Incorporating data of student engagement and active involvement could help to deduce the interest of a learner, which is known to improve sensitisation in implicit, incidental and also in classical learning. Experimental settings used in previous studies attempting to incorporate physiological responses and interpretations into responsive educational settings have faced major obstacles. Operational issues caused by the requirements of the devices used for the acquisition of physiological signals such as electrodes and movement restrictions have reduced the progress of such settings to laboratory environments. In such settings as described above, the effects of wiring harnesses and sensory components produced an additional psychological burden on the participants. Consequently, the need to approach the physiological data acquisition from a new angle with seamless and unnoticeable operation is apparent. The challenge to design, develop and validate a system that being minimally obstructive and literally unnoticed by the user would uncover combined subconscious expressions of a learner was the primary objective of this research. Physiological data of Heart Rate and Skin Trans-Conductance (Electro-dermal Response) elected as vitally important and highly appropriate to produce the input of data required to evaluate a behavioural concept model. The behavioural assessment model entailed vector classifiers producing directional interpretations of measurements.…

Subjects/Keywords: Βιο - αναδραστική ανίχνευση εμπλοκής σε περιεχόμενο; Εργαλεία ανάλυσης αλληλεπιδράσεων; Εμπλοκή χρήστη Η/Υ στο περιεχόμενο; Ηλεκτρονικό κύκλωμα μέτρησης καρδιακού παλμού και διηλεκτρικής αγωγιμότητας του δέρματος; Μοντελοποίηση νευροφυσιολογικών μετρήσεων σε μοντέλο του Russell; Biofeedback sensing of engagement; Tools for adaptive computing; User engagement; Electronic circuit for heart rate and skin trans - conductance; Modelling of neurophysiological measurements using russell's model

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Psaltis, A. (2018). Design and development of a real time bio-sensing system assessing student mental workload and engagement. (Thesis). National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Retrieved from http://hdl.handle.net/10442/hedi/44400

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Psaltis, Antonios. “Design and development of a real time bio-sensing system assessing student mental workload and engagement.” 2018. Thesis, National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Accessed January 19, 2021. http://hdl.handle.net/10442/hedi/44400.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Psaltis, Antonios. “Design and development of a real time bio-sensing system assessing student mental workload and engagement.” 2018. Web. 19 Jan 2021.

Vancouver:

Psaltis A. Design and development of a real time bio-sensing system assessing student mental workload and engagement. [Internet] [Thesis]. National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ); 2018. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/10442/hedi/44400.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Psaltis A. Design and development of a real time bio-sensing system assessing student mental workload and engagement. [Thesis]. National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ); 2018. Available from: http://hdl.handle.net/10442/hedi/44400

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

29. Theodorakis, Lampros. Βελτιστοποίηση της λειτουργίας συστημάτων τομογραφίας εκπομπής ποζιτρονίων (PET).

Degree: 2020, University of Thessaly (UTH); Πανεπιστήμιο Θεσσαλίας

URL: http://hdl.handle.net/10442/hedi/46978

►

In the present dissertation, PET/CT (hybrid Positron Emission Tomography and Computed Tomography) systems were modeled using appropriate software. These models are then used to optimize… (more)

▼

In the present dissertation, PET/CT (hybrid Positron Emission Tomography and Computed Tomography) systems were modeled using appropriate software. These models are then used to optimize their operation. The optimization of the operation was not only focused on the determination of the technical parameters of the detector and the geometry of the PET system, but also extended to the clinical context, this being the ultimate goal of the thesis. These optimizations are aimed at improving the quantitative results of the functional imaging of radiopharmaceutical uptaking tumors or assuring their repeatability. The anatomy chosen is the thorax and the type of lesion is the Solitary Pulmonary Nodule (SPN). The selection was based on various features and properties such as its small size, as well as the fact that its relative position in the thorax may be related to its prognosis. This practically means that the PET camera is required to operate in such a way, so that the quantitative or semi-quantitative results it produces are reproducible. The first part of the thesis focuses on building the simulation model and listing the corresponding results with emphasis on possible optimization schemes. Our results show that properly tuned Monte Carlo simulations predict accurately the count rates of the detectors, representing all the respective phenomena starting from the initial gamma emission to the allocation of the counts on the respective Lines of Response (LOR) in the sinogrammed raw data. A maximum deviation of 2% when comparing simulations and experiments validates the model accuracy for further use in the clinical context. On this basis, in the second part of the dissertation we use experimentally validated simulations, and the performance of the measurements of four different scanner models of a model of true clinical patient data with detected SPN is represented using the parameter of NECR (Noise Equivalent Count Rate). The response of this parameter is investigated with regards to its activity, its relative location in the thorax and the degree of obesity of patients. Significant fluctuation of the quantitative results is observed when the same patient is scanned in different detector configurations of scanner models, or even in the case of the same detectors where however the scans are taken at different time points and the patient characteristics (weight) have changed in-between. Non-optimal patient positioning eccentric to the isocenter is observed frequently and can potentially contribute further to result variability. Our results provide evidence of the ability for properly tuned simulations to be incorporated into daily clinical practice and provide additional information on the variability of response of PET camera measurements, especially in types of lesions where often borderline decisions are made regarding their characterization. Future work is the exploration of the possibility to use the method prescribed here in an extended clinical trial (e.g. on a country level).

Στα πλαίσια της παρούσας διατριβής…

Subjects/Keywords: PET (Ποζιτρονική Τομογραφία); Αρχή λειτουργίας κάμερας PET; Μονήρης πνευμονικός όζος; PET (Positron emission tomography)

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Theodorakis, L. (2020). Βελτιστοποίηση της λειτουργίας συστημάτων τομογραφίας εκπομπής ποζιτρονίων (PET). (Thesis). University of Thessaly (UTH); Πανεπιστήμιο Θεσσαλίας. Retrieved from http://hdl.handle.net/10442/hedi/46978

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Theodorakis, Lampros. “Βελτιστοποίηση της λειτουργίας συστημάτων τομογραφίας εκπομπής ποζιτρονίων (PET).” 2020. Thesis, University of Thessaly (UTH); Πανεπιστήμιο Θεσσαλίας. Accessed January 19, 2021. http://hdl.handle.net/10442/hedi/46978.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Theodorakis, Lampros. “Βελτιστοποίηση της λειτουργίας συστημάτων τομογραφίας εκπομπής ποζιτρονίων (PET).” 2020. Web. 19 Jan 2021.

Vancouver:

Theodorakis L. Βελτιστοποίηση της λειτουργίας συστημάτων τομογραφίας εκπομπής ποζιτρονίων (PET). [Internet] [Thesis]. University of Thessaly (UTH); Πανεπιστήμιο Θεσσαλίας; 2020. [cited 2021 Jan 19]. Available from: http://hdl.handle.net/10442/hedi/46978.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Theodorakis L. Βελτιστοποίηση της λειτουργίας συστημάτων τομογραφίας εκπομπής ποζιτρονίων (PET). [Thesis]. University of Thessaly (UTH); Πανεπιστήμιο Θεσσαλίας; 2020. Available from: http://hdl.handle.net/10442/hedi/46978

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universiteit Utrecht

30. Keijsers, R.G.M. 18F-FDG PET in sarcoidosis.

Degree: 2010, Universiteit Utrecht

URL: http://dspace.library.uu.nl:8080/handle/1874/188222

► Sarcoidosis is a granulomatous disease of unknown cause. It can affect all organs although the lungs, eyes and skin are most frequently involved. The presence… (more)

▼ Sarcoidosis is a granulomatous disease of unknown cause. It can affect all organs although the lungs, eyes and skin are most frequently involved. The presence of active disease is currently based on several parameters such as symptoms, clinical findings, the serum markers angiotensin converting enzyme (ACE) and soluble interleukin-2 receptor (sIL-2R), chest radiography, pulmonary function tests (PFT) and bronchoalveolar lavage (BAL). However, a gold standard for the assessment of active disease is unavailable. Therefore, the use of ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) PET in the assessment of sarcoidosis activity was evaluated and compared with the aforementioned markers for active disease. The following conclusions may be drawn from the studies described in this thesis: Compared to 67Ga scintigraphy, ¹⁸F-FDG PET is more sensitive in assessing sarcoidosis activity and demonstrates a higher inter observer agreement ¹⁸F-FDG PET appears more sensitive than genotype corrected ACE and sIL-2R in determining the presence of active disease The degree of metabolic activity in the pulmonary tract imaged by ¹⁸F-FDG PET and expressed as maximum standardized uptake value (SUVmax), correlates with the CD4+/CD8+ ratio and neutrophils in BAL In untreated patients, the absence of parenchymal activity imaged by ¹⁸F-FDG PET correlates with stable pulmonary function tests after one year, while diffuse parenchymal activity predicts a decrease in diffusion capacity of the lung for carbon monoxide (DLCO) In patients with diffuse parenchymal activity imaged by ¹⁸F-FDG PET, pulmonary function tests improve by using immunosuppressive therapy, suggesting that ¹⁸F-FDG PET presents the possible improvement that can be achieved In chronic sarcoidosis patients treated with infliximab, changes in ¹⁸F-FDG PET correlate with the clinically observed response In chronic sarcoidosis patients, the change in SUVmax of the lung parenchyma correlates with the change in vital capacity (VC) attained by infliximab therapy An ¹⁸F-FDG PET based classification system of sarcoidosis incorporating four major phenotypic presentations is reproducible. Advisors/Committee Members: Bosch, J.M.M. van den, Oyen, W.J.G., Verzijlbergen, J.F., Grutters, J.C..

Subjects/Keywords: Geneeskunde; FDG PET; sarcoidosis

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Keijsers, R. G. M. (2010). 18F-FDG PET in sarcoidosis. (Doctoral Dissertation). Universiteit Utrecht. Retrieved from http://dspace.library.uu.nl:8080/handle/1874/188222

Chicago Manual of Style (16^th Edition):

Keijsers, R G M. “18F-FDG PET in sarcoidosis.” 2010. Doctoral Dissertation, Universiteit Utrecht. Accessed January 19, 2021. http://dspace.library.uu.nl:8080/handle/1874/188222.

MLA Handbook (7^th Edition):

Keijsers, R G M. “18F-FDG PET in sarcoidosis.” 2010. Web. 19 Jan 2021.

Vancouver:

Keijsers RGM. 18F-FDG PET in sarcoidosis. [Internet] [Doctoral dissertation]. Universiteit Utrecht; 2010. [cited 2021 Jan 19]. Available from: http://dspace.library.uu.nl:8080/handle/1874/188222.

Council of Science Editors:

Keijsers RGM. 18F-FDG PET in sarcoidosis. [Doctoral Dissertation]. Universiteit Utrecht; 2010. Available from: http://dspace.library.uu.nl:8080/handle/1874/188222

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Open Access Theses and Dissertations