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You searched for subject:(N sulfinylaziridines). One record found.

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1. Callebaut, Gert. Synthesis and applications of chiral N-sulfinylimines and -aziridines as versatile building blocks in organic chemistry.

Degree: 2013, Ghent University

Nucleophilic ring opening of N-protected aziridines is known as one of the scarce methods for the incorporation of a protected amino-ethyl unit (-CR1R2CR3R4NR5R6) in a stereo- and regioselective way in organic synthesis. This amino-ethyl unit can be found in a wide range of natural products and N-containing drugs. These N-protected aziridines constitute an important group of target molecules in the synthetic organic chemistry, due to their biological activity as well as their structural complexity. This PhDthesis comprises the development of new chiral N-sulfinylaziridines, using a diastereoselective Mannich-type addition of N-protected glycine derivatives across chiral α-functionalized-N sulfinylimines. Hereby, an efficient synthesis of a wide range of new chiral aziridines is presented which can be applied as starting products for the synthesis of new heterocyclic compounds. Advisors/Committee Members: Mangelinckx, Sven, De Kimpe, Norbert.

Subjects/Keywords: Chemistry; N-sulfinylaziridines; chiral; N-sulfinylimine

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APA (6th Edition):

Callebaut, G. (2013). Synthesis and applications of chiral N-sulfinylimines and -aziridines as versatile building blocks in organic chemistry. (Thesis). Ghent University. Retrieved from http://hdl.handle.net/1854/LU-4206059

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Callebaut, Gert. “Synthesis and applications of chiral N-sulfinylimines and -aziridines as versatile building blocks in organic chemistry.” 2013. Thesis, Ghent University. Accessed November 30, 2020. http://hdl.handle.net/1854/LU-4206059.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Callebaut, Gert. “Synthesis and applications of chiral N-sulfinylimines and -aziridines as versatile building blocks in organic chemistry.” 2013. Web. 30 Nov 2020.

Vancouver:

Callebaut G. Synthesis and applications of chiral N-sulfinylimines and -aziridines as versatile building blocks in organic chemistry. [Internet] [Thesis]. Ghent University; 2013. [cited 2020 Nov 30]. Available from: http://hdl.handle.net/1854/LU-4206059.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Callebaut G. Synthesis and applications of chiral N-sulfinylimines and -aziridines as versatile building blocks in organic chemistry. [Thesis]. Ghent University; 2013. Available from: http://hdl.handle.net/1854/LU-4206059

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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