You searched for subject:(Myopia).
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University of Johannesburg
1.
Smith, Debbie.
The effects of physostigma 30ch and combined with the Bates method on the management of myopia.
Degree: 2014, University of Johannesburg
URL: http://hdl.handle.net/10210/9005 
► M.Tech. (Biotechnology)
Spectacles and contact lenses are the most widely used optical appliances to manage myopia. Surgical techniques are an alternative but the outcome of…
(more)
▼ M.Tech. (Biotechnology)
Spectacles and contact lenses are the most widely used optical appliances to manage myopia. Surgical techniques are an alternative but the outcome of surgery can be unpredictable and the procedures are costly. Myopia, or nearsightedness, is a condition characterised by blurred distant vision. Both a more lasting cure and a more cost-effective alternative solution in the treatment of myopia are desirable. The effectiveness of the homoeopathic remedy, Physostigma 30CH on its own, the Bates method on its own and a combination of the homoeopathic remedy and the Bates method in reducing myopia were determined. Thirty suitable myopic subjects between the ages of 21 - 34 years were selected. Subjects were paired in terms of age, race and sex on a double-blind basis. This research was conducted in three stages of thirty days each. During stage one the experimental group performed the Bates method, while the control group performed the modified Bates method. During stage two the experimental group received the .homoeopathic remedy, Physostigma 30CH, whilst the control group received a placebo. During stage three the experimental group performed the Bates method and received the homoeopathic remedy, Physostigma 30CH, whilst the control group performed the modified Bates method and received the placebo. Each subject underwent an optometric examination before and after each of the abovementioned stages. During the eye examination, the aided and unaided visual acuity, left and right refractions, accommodative flexibility and accommodation amplitude were determined by a qualified optometrist. After each eye examination a questionnaire was completed to determine the patient's subjective feelings ofthe treatment. The data was analyzed using a 2-sample t-test (incorporating the Levence test) for determining the statistical significance within each different stage of the research. The significant (2-tailed) p-values for the statistical significance between the two groups were obtained in order to indicate whether there was a reduction in myopia in either the experimental or the control group or both.
Subjects/Keywords: Myopia; Homeopathy
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APA (6th Edition):
Smith, D. (2014). The effects of physostigma 30ch and combined with the Bates method on the management of myopia. (Thesis). University of Johannesburg. Retrieved from http://hdl.handle.net/10210/9005
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Smith, Debbie. “The effects of physostigma 30ch and combined with the Bates method on the management of myopia.” 2014. Thesis, University of Johannesburg. Accessed January 25, 2021.
http://hdl.handle.net/10210/9005.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Smith, Debbie. “The effects of physostigma 30ch and combined with the Bates method on the management of myopia.” 2014. Web. 25 Jan 2021.
Vancouver:
Smith D. The effects of physostigma 30ch and combined with the Bates method on the management of myopia. [Internet] [Thesis]. University of Johannesburg; 2014. [cited 2021 Jan 25].
Available from: http://hdl.handle.net/10210/9005.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Smith D. The effects of physostigma 30ch and combined with the Bates method on the management of myopia. [Thesis]. University of Johannesburg; 2014. Available from: http://hdl.handle.net/10210/9005
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Manchester
2.
Hartwig, Andreas.
The influence of optics, peripheral refraction and
posture on refractive error development.
Degree: 2012, University of Manchester
URL: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:153656
► The aim of the present project was to analyse the link between peripheral posture, optics, optics and refractive error progression. Preliminary studies were conducted to…
(more)
▼ The aim of the present project was to analyse the
link between peripheral posture, optics, optics and refractive
error progression. Preliminary studies were conducted to ensure
that peripheral aberrometry is valid for further analysis. The
repeatability of the IRX-3 for peripheral aberrometry was asgood as
for central measurements and the recalculation of elliptical pupils
did not seem to be necessary for measurements up to 20 degrees
eccentricity. Higher order aberration measurements werecomparable
to other studies.Eye and head movements as well as working distance
did not differ significantly between myopes and non-myopes.
However, there was some evidence, that forward bending of the head
during reading increases in association with higher refractive
error progression rates.The link between central higher order
aberrations and refractive error development was analysed by
comparing higher order aberrations between isometropes and
anisometropes. This analysisdid not show any significant
association of higher order aberrations on the development, as no
major differences were found between the two groups. For central
vision, changes in biometric parameters during accommodation were
analysed. It was found that biometric parameters change similarly
in myopes and non-myopes.Peripheral accommodation was found to
differ between myopes and emmetropes indicating that there might be
an influence of peripheral refraction on myopisation. However,
associationbetween peripheral refraction or peripheral aberrations
and refractive error progression were not significant. The reason
for this observation might be the low refractive error progression
(0.04± 0.29 D in myopes and -0.12 ± 0.38 D in emmetropes) during
one year in the study population.
Advisors/Committee Members: MURRAY, IAN IJ, Murray, Ian, Radhakrishnan, Hema.
Subjects/Keywords: myopia; peripher refraction
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Manager
APA (6th Edition):
Hartwig, A. (2012). The influence of optics, peripheral refraction and
posture on refractive error development. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:153656
Chicago Manual of Style (16th Edition):
Hartwig, Andreas. “The influence of optics, peripheral refraction and
posture on refractive error development.” 2012. Doctoral Dissertation, University of Manchester. Accessed January 25, 2021.
http://www.manchester.ac.uk/escholar/uk-ac-man-scw:153656.
MLA Handbook (7th Edition):
Hartwig, Andreas. “The influence of optics, peripheral refraction and
posture on refractive error development.” 2012. Web. 25 Jan 2021.
Vancouver:
Hartwig A. The influence of optics, peripheral refraction and
posture on refractive error development. [Internet] [Doctoral dissertation]. University of Manchester; 2012. [cited 2021 Jan 25].
Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:153656.
Council of Science Editors:
Hartwig A. The influence of optics, peripheral refraction and
posture on refractive error development. [Doctoral Dissertation]. University of Manchester; 2012. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:153656
Durban University of Technology
3.
Pillay, Bavani.
The effect of physostigma venenosum om myopia.
Degree: 1994, Durban University of Technology
URL: http://hdl.handle.net/10321/2704
► Dissertation submitted in partial compliance with the requirements for the Master's Diploma in Technology, Homoeopathy at Technikon Natal, 1994.
The purpose of this project was…
(more)
▼ Dissertation submitted in partial compliance with the requirements for the Master's Diploma in Technology, Homoeopathy at Technikon Natal, 1994.
The purpose of this project was to determine how effective Physostigma venenosum is as a Homoeopathic treatment of myopia. Myopia does not have a history of spontaneous remission, therefore some form of treatment is required. Glasses and contact lenses, both widely used, have been of tremendous value in relieving the symptoms\xB7 of myopia.
M
Advisors/Committee Members: Burger, F. J..
Subjects/Keywords: Homeopathy; Myopia
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APA (6th Edition):
Pillay, B. (1994). The effect of physostigma venenosum om myopia. (Thesis). Durban University of Technology. Retrieved from http://hdl.handle.net/10321/2704
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Pillay, Bavani. “The effect of physostigma venenosum om myopia.” 1994. Thesis, Durban University of Technology. Accessed January 25, 2021.
http://hdl.handle.net/10321/2704.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Pillay, Bavani. “The effect of physostigma venenosum om myopia.” 1994. Web. 25 Jan 2021.
Vancouver:
Pillay B. The effect of physostigma venenosum om myopia. [Internet] [Thesis]. Durban University of Technology; 1994. [cited 2021 Jan 25].
Available from: http://hdl.handle.net/10321/2704.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Pillay B. The effect of physostigma venenosum om myopia. [Thesis]. Durban University of Technology; 1994. Available from: http://hdl.handle.net/10321/2704
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Penn State University
4.
Alhusaini, Badryah Y.
Peer Information and Managerial Myopia.
Degree: 2019, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/17037bya101
► This paper examines the effect of peer information on managerial myopia. If greater peer information is beneficial, investors will face less uncertainty about the firm’s…
(more)
▼ This paper examines the effect of peer information on managerial
myopia. If greater peer information is beneficial, investors will face less uncertainty about the firm’s own prospects and thus fixate less on current earnings. As a result, managers can face less pressure to focus on boosting short-term performance to signal high firm type. Using the percentage of public firms in the industry (i.e. “public firm presence”) as a measure of peer information, I find that managers in industries with greater public firm presence are less myopic. This effect of peer information reducing
myopia is less pronounced in instances in which the manager is more pressured to meet short-term benchmarks, as measured by analyst coverage and transient ownership. Finally, I find that, for firms with greater public firm presence, investors face less information asymmetry and react less negatively when those firms miss an earnings benchmark, consistent with greater levels of peer information reducing
myopia by facilitating investors to assess the firm more effectively.
Advisors/Committee Members: Karl Muller, Dissertation Advisor/Co-Advisor, Karl A Muller, III, Committee Chair/Co-Chair, Dan Givoly, Committee Member, Hal Derric White, Committee Member, Peter G Iliev, Outside Member.
Subjects/Keywords: Managerial Myopia; Peer Information
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APA ·
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APA (6th Edition):
Alhusaini, B. Y. (2019). Peer Information and Managerial Myopia. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/17037bya101
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Alhusaini, Badryah Y. “Peer Information and Managerial Myopia.” 2019. Thesis, Penn State University. Accessed January 25, 2021.
https://submit-etda.libraries.psu.edu/catalog/17037bya101.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Alhusaini, Badryah Y. “Peer Information and Managerial Myopia.” 2019. Web. 25 Jan 2021.
Vancouver:
Alhusaini BY. Peer Information and Managerial Myopia. [Internet] [Thesis]. Penn State University; 2019. [cited 2021 Jan 25].
Available from: https://submit-etda.libraries.psu.edu/catalog/17037bya101.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Alhusaini BY. Peer Information and Managerial Myopia. [Thesis]. Penn State University; 2019. Available from: https://submit-etda.libraries.psu.edu/catalog/17037bya101
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
5.
Labhishetty, Vivek.
Understanding the sensory and motor behavior of accommodation in progressive myopic children.
Degree: 2017, University of Waterloo
URL: http://hdl.handle.net/10012/12484
► Introduction: Accommodation and vergence, in unison, help in maintaining a clear and single binocular vision, a linchpin for normal vision development. Under natural viewing conditions,…
(more)
▼ Introduction: Accommodation and vergence, in unison, help in maintaining a clear and single binocular vision, a linchpin for normal vision development. Under natural viewing conditions, accommodation and vergence systems mutually interact with each other through a unique cross-link mechanism. Based on the empirical data from visually normal adults, several control theory models were proposed to predict the behavior of accommodation and vergence. Progressive myopic children, however, exhibit a transient but consistent abnormal accommodative behavior which is not predicted by the currently accepted models. Progressive myopes exhibit high accommodative adaptation, elevated AC output coupled with high accommodative lags. Several predictions, both sensory and motor origin, have been proposed to explain this behavior however they failed to predict this behavior completely. Furthermore, empirical conclusions on the impact of myopia over accommodation and blur sensitivity were mostly based on data obtained from adult population. Accordingly, this dissertation examined the sensory and motor mechanism of accommodation in young children with and without progressive myopia. Data from children were also compared to adults.
Methods: 12 children (8-13 years), 6 myopic and 6 non-myopic, and 6 naïve adults (25-33 years) were recruited for the purpose of this dissertation. Varying demands of accommodation were stimulated using a Badal optical system and recorded using custom-built dynamic photorefraction system (DPRS). Theoretical and empirical designs were developed to identify the ideal sampling rate necessary to measure a dynamic accommodative response. First and second order main sequence relationship and strength of the cross-link (CA) response was tested in the first experiment. In the second experiment, blur discrimination thresholds were tested psychophysically using simulated blur targets at two different stimulus demands. Furthermore, objective DOF and sensitivity of accommodative system to blur were examined using known demands of lens defocus and compared across different subject groups.
Results: The new custom built high speed photorefractor (DPRS) was found to be superior in measuring dynamic accommodation compared to the commercially available Power Refractor (p <0.001). The current dissertation makes four major contributions to the field of accommodation and myopia: first, a motor deficit such as a sluggish or rigid plant cannot explain the abnormal behavior of accommodation in myopes. This was established based on the findings of a similar first and second order main sequence relationship between myopes and non-myopes (p > 0.05). Also, CA/C measures were not found to be attenuated as would be expected with a rigid plant. Novel simulations with reduced blur sensitivity coupled with a motor recalibration of AC gain did predict the myopic behavior. Second, atypical response patterns of accommodation such as the dynamic overshoots and double step responses were reported to exist with blur-driven accommodation. These…
Subjects/Keywords: Myopia; Accommodation; Blur sensitivity
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APA ·
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to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Labhishetty, V. (2017). Understanding the sensory and motor behavior of accommodation in progressive myopic children. (Thesis). University of Waterloo. Retrieved from http://hdl.handle.net/10012/12484
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Labhishetty, Vivek. “Understanding the sensory and motor behavior of accommodation in progressive myopic children.” 2017. Thesis, University of Waterloo. Accessed January 25, 2021.
http://hdl.handle.net/10012/12484.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Labhishetty, Vivek. “Understanding the sensory and motor behavior of accommodation in progressive myopic children.” 2017. Web. 25 Jan 2021.
Vancouver:
Labhishetty V. Understanding the sensory and motor behavior of accommodation in progressive myopic children. [Internet] [Thesis]. University of Waterloo; 2017. [cited 2021 Jan 25].
Available from: http://hdl.handle.net/10012/12484.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Labhishetty V. Understanding the sensory and motor behavior of accommodation in progressive myopic children. [Thesis]. University of Waterloo; 2017. Available from: http://hdl.handle.net/10012/12484
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Manchester
6.
Dai, Shiji.
Partial Myopia, Downside Risk Aversion and Its
Application in Option Pricing.
Degree: 2015, University of Manchester
URL: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:260000
► The aim of this thesis is to extend the current research on portfolio investment and asset pricing under uncertainty with a special focus on partial…
(more)
▼ The aim of this thesis is to extend the current
research on portfolio investment and asset pricing under
uncertainty with a special focus on partial
myopia and downside
risk aversion. To address this goal, the thesis first proposes the
use of partial
myopia as an alternative approach to dynamic
programming for solving a multi-period investment problem with
background risks. I provide numerical examples to show that the
partial
myopia approach could lead to the same optimal investment
decision as the dynamic programming method, even in the presence of
background risks. Next, the thesis explores the drawbacks of the
five existing downside risk aversion measures, and proposes a new
local measure. While the proposed measure is limited by its local
property, our numerical examples show that it gives the right
preference ordering while the other five measures provide
inconsistent signals. Finally, the thesis investigates the
relationship between downside risk aversion and option pricing by
analysing the elasticity of the pricing kernel. We conclude that
decreasing absolute risk aversion and increasing downside risk
aversion will increase the option price given the forward price.
However, the two risk measures are not independent, and they
interact to affect option price jointly.
Advisors/Committee Members: Poon, Ser-Huang.
Subjects/Keywords: Partial Myopia; Downside Risk Aversion
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Dai, S. (2015). Partial Myopia, Downside Risk Aversion and Its
Application in Option Pricing. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:260000
Chicago Manual of Style (16th Edition):
Dai, Shiji. “Partial Myopia, Downside Risk Aversion and Its
Application in Option Pricing.” 2015. Doctoral Dissertation, University of Manchester. Accessed January 25, 2021.
http://www.manchester.ac.uk/escholar/uk-ac-man-scw:260000.
MLA Handbook (7th Edition):
Dai, Shiji. “Partial Myopia, Downside Risk Aversion and Its
Application in Option Pricing.” 2015. Web. 25 Jan 2021.
Vancouver:
Dai S. Partial Myopia, Downside Risk Aversion and Its
Application in Option Pricing. [Internet] [Doctoral dissertation]. University of Manchester; 2015. [cited 2021 Jan 25].
Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:260000.
Council of Science Editors:
Dai S. Partial Myopia, Downside Risk Aversion and Its
Application in Option Pricing. [Doctoral Dissertation]. University of Manchester; 2015. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:260000
University of Manchester
7.
Dai, Shiji.
Partial myopia, downside risk aversion and its application in option pricing.
Degree: PhD, 2015, University of Manchester
URL: https://www.research.manchester.ac.uk/portal/en/theses/partial-myopia-downside-risk-aversion-and-its-application-in-option-pricing(b5280b3e-3367-459b-97a7-3c74ec57154f).html
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.771319
► The aim of this thesis is to extend the current research on portfolio investment and asset pricing under uncertainty with a special focus on partial…
(more)
▼ The aim of this thesis is to extend the current research on portfolio investment and asset pricing under uncertainty with a special focus on partial myopia and downside risk aversion. To address this goal, the thesis first proposes the use of partial myopia as an alternative approach to dynamic programming for solving a multi-period investment problem with background risks. I provide numerical examples to show that the partial myopia approach could lead to the same optimal investment decision as the dynamic programming method, even in the presence of background risks. Next, the thesis explores the drawbacks of the five existing downside risk aversion measures, and proposes a new local measure. While the proposed measure is limited by its local property, our numerical examples show that it gives the right preference ordering while the other five measures provide inconsistent signals. Finally, the thesis investigates the relationship between downside risk aversion and option pricing by analysing the elasticity of the pricing kernel. We conclude that decreasing absolute risk aversion and increasing downside risk aversion will increase the option price given the forward price. However, the two risk measures are not independent, and they interact to affect option price jointly.
Subjects/Keywords: Partial Myopia; Downside Risk Aversion
Record Details
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Dai, S. (2015). Partial myopia, downside risk aversion and its application in option pricing. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/partial-myopia-downside-risk-aversion-and-its-application-in-option-pricing(b5280b3e-3367-459b-97a7-3c74ec57154f).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.771319
Chicago Manual of Style (16th Edition):
Dai, Shiji. “Partial myopia, downside risk aversion and its application in option pricing.” 2015. Doctoral Dissertation, University of Manchester. Accessed January 25, 2021.
https://www.research.manchester.ac.uk/portal/en/theses/partial-myopia-downside-risk-aversion-and-its-application-in-option-pricing(b5280b3e-3367-459b-97a7-3c74ec57154f).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.771319.
MLA Handbook (7th Edition):
Dai, Shiji. “Partial myopia, downside risk aversion and its application in option pricing.” 2015. Web. 25 Jan 2021.
Vancouver:
Dai S. Partial myopia, downside risk aversion and its application in option pricing. [Internet] [Doctoral dissertation]. University of Manchester; 2015. [cited 2021 Jan 25].
Available from: https://www.research.manchester.ac.uk/portal/en/theses/partial-myopia-downside-risk-aversion-and-its-application-in-option-pricing(b5280b3e-3367-459b-97a7-3c74ec57154f).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.771319.
Council of Science Editors:
Dai S. Partial myopia, downside risk aversion and its application in option pricing. [Doctoral Dissertation]. University of Manchester; 2015. Available from: https://www.research.manchester.ac.uk/portal/en/theses/partial-myopia-downside-risk-aversion-and-its-application-in-option-pricing(b5280b3e-3367-459b-97a7-3c74ec57154f).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.771319
University of Manchester
8.
Hartwig, Andreas.
The influence of optics, peripheral refraction and posture on refractive error development.
Degree: PhD, 2012, University of Manchester
URL: https://www.research.manchester.ac.uk/portal/en/theses/the-influence-of-optics-peripheral-refraction-and-posture-on-refractive-error-development(f0382767-3194-4631-8cab-d473d64900bd).html
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.549010
► The aim of the present project was to analyse the link between peripheral posture, optics, optics and refractive error progression. Preliminary studies were conducted to…
(more)
▼ The aim of the present project was to analyse the link between peripheral posture, optics, optics and refractive error progression. Preliminary studies were conducted to ensure that peripheral aberrometry is valid for further analysis. The repeatability of the IRX-3 for peripheral aberrometry was asgood as for central measurements and the recalculation of elliptical pupils did not seem to be necessary for measurements up to 20 degrees eccentricity. Higher order aberration measurements werecomparable to other studies. Eye and head movements as well as working distance did not differ significantly between myopes and non-myopes. However, there was some evidence, that forward bending of the head during reading increases in association with higher refractive error progression rates. The link between central higher order aberrations and refractive error development was analysed by comparing higher order aberrations between isometropes and anisometropes. This analysisdid not show any significant association of higher order aberrations on the development, as no major differences were found between the two groups. For central vision, changes in biometric parameters during accommodation were analysed. It was found that biometric parameters change similarly in myopes and non-myopes. Peripheral accommodation was found to differ between myopes and emmetropes indicating that there might be an influence of peripheral refraction on myopisation. However, associationbetween peripheral refraction or peripheral aberrations and refractive error progression were not significant. The reason for this observation might be the low refractive error progression (0.04± 0.29 D in myopes and -0.12 ± 0.38 D in emmetropes) during one year in the study population.
Subjects/Keywords: 570; myopia; peripher refraction
Record Details
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Hartwig, A. (2012). The influence of optics, peripheral refraction and posture on refractive error development. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/the-influence-of-optics-peripheral-refraction-and-posture-on-refractive-error-development(f0382767-3194-4631-8cab-d473d64900bd).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.549010
Chicago Manual of Style (16th Edition):
Hartwig, Andreas. “The influence of optics, peripheral refraction and posture on refractive error development.” 2012. Doctoral Dissertation, University of Manchester. Accessed January 25, 2021.
https://www.research.manchester.ac.uk/portal/en/theses/the-influence-of-optics-peripheral-refraction-and-posture-on-refractive-error-development(f0382767-3194-4631-8cab-d473d64900bd).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.549010.
MLA Handbook (7th Edition):
Hartwig, Andreas. “The influence of optics, peripheral refraction and posture on refractive error development.” 2012. Web. 25 Jan 2021.
Vancouver:
Hartwig A. The influence of optics, peripheral refraction and posture on refractive error development. [Internet] [Doctoral dissertation]. University of Manchester; 2012. [cited 2021 Jan 25].
Available from: https://www.research.manchester.ac.uk/portal/en/theses/the-influence-of-optics-peripheral-refraction-and-posture-on-refractive-error-development(f0382767-3194-4631-8cab-d473d64900bd).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.549010.
Council of Science Editors:
Hartwig A. The influence of optics, peripheral refraction and posture on refractive error development. [Doctoral Dissertation]. University of Manchester; 2012. Available from: https://www.research.manchester.ac.uk/portal/en/theses/the-influence-of-optics-peripheral-refraction-and-posture-on-refractive-error-development(f0382767-3194-4631-8cab-d473d64900bd).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.549010
University of New South Wales
9.
Philip, Krupa.
Influence of ocular monochromatic aberrations in the development and/or progression of myopia.
Degree: Optometry & Vision Science, 2012, University of New South Wales
URL: http://handle.unsw.edu.au/1959.4/52428
;
https://unsworks.unsw.edu.au/fapi/datastream/unsworks:11101/SOURCE01?view=true
► Aim: To determine an association if any, between ‘on’ and ‘off-axis’ ocular aberrations and a myopic change in refractive error using the data obtained longitudinally.…
(more)
▼ Aim: To determine an association if any, between ‘on’ and ‘off-axis’ ocular aberrations and a myopic change in refractive error using the data obtained longitudinally. Methods: On and off-axis aberrations of cyclopleged eyes (5 mm pupil diameter) of 646 children were measured during 2004-2005 (age, 12.7 ± 0.4 years) and 5 years later in 2009-2010 (age, 17.1 ± 0.5 years). Change in spherical equivalent (M) from baseline to follow-up visit was determined and eyes characterised as ‘myopic change’ (≥ 0.50D), ‘no change’ (from 0.49D to +0.49D) and ‘hyperopic change’ (≥ +0.50D). Baseline data of eyes with ‘myopic change’ and ‘no change’ were compared to determine if any baseline characteristics predicted a future myopic change. Also, the change in ‘on’ and ‘off-axis’ aberrations with time were correlated with change in M, using general linear model. Significance level was set at p<0.05. Additionally, data from 675 adolescents (16.0 ± 0.7 yrs) were analysed to determine the contribution of corneal and internal aberrations to total aberrations. Results: At baseline 15% of eyes were myopic, 27% emmetropic and 58% hyperopic. 26%, 70% and 4% of all eyes showed myopic change, no change and hyperopic change respectively. None of the baseline ‘on’ and ‘off-axis’ aberrations and retinal image quality measures was associated with a ‘myopic change’ in M. With time, eyes with ‘myopic change’ showed a decrease in on-axis spherical aberration [C(4,0)] and a hyperopic shift in relative peripheral refractive error (RPRE), whereas eyes with ‘no change’ had an increase in on-axis C(4,0) and no difference in RPRE. Eyes with Type III and Type IV skiagram at baseline showed the most (61%) and the least (17%) myopic change respectively. Across refractive error (RE) groups, corneal aberrations were not different and were compensated for with internal aberrations resulting in less net total aberrations. However, internal aberrations differed between RE groups with less negative internal C(4,0) observed in hyperopes (-0.038 ± 0.05 μm) compared to emmetropes (-0.081 ± 0.04 μm) and myopes (-0.090 ± 0.04 μm). Conclusion: None of the baseline ‘on and ‘off-axis’ aberrations predicted a future myopic change in refractive error. However, the eyes with Type III skiagram (asymmetry in astigmatism in nasal and temporal quadrants) showed the most myopic change in refraction. It may be possible this asymmetry in astigmatism (characteristic feature of Type III skiagram) observed at temporal retina could play a role in myopic change and needs to be explored further. The hyperopic shift in RPRE with time for eyes with ‘myopic change’ is possibly a consequence of ocular growth. The variation in internal C(4,0) between refractive error groups and differences in C(4,0) with time in eyes with ‘myopic change’ versus ‘no change’ directs focus to the…
Advisors/Committee Members: Sankaridurg, Padmaja, Optometry & Vision Science, Faculty of Science, UNSW, Holden, Brien, Optometry & Vision Science, Faculty of Science, UNSW.
Subjects/Keywords: Peripheral refraction; Myopia; Ocular aberrations
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APA (6th Edition):
Philip, K. (2012). Influence of ocular monochromatic aberrations in the development and/or progression of myopia. (Doctoral Dissertation). University of New South Wales. Retrieved from http://handle.unsw.edu.au/1959.4/52428 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:11101/SOURCE01?view=true
Chicago Manual of Style (16th Edition):
Philip, Krupa. “Influence of ocular monochromatic aberrations in the development and/or progression of myopia.” 2012. Doctoral Dissertation, University of New South Wales. Accessed January 25, 2021.
http://handle.unsw.edu.au/1959.4/52428 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:11101/SOURCE01?view=true.
MLA Handbook (7th Edition):
Philip, Krupa. “Influence of ocular monochromatic aberrations in the development and/or progression of myopia.” 2012. Web. 25 Jan 2021.
Vancouver:
Philip K. Influence of ocular monochromatic aberrations in the development and/or progression of myopia. [Internet] [Doctoral dissertation]. University of New South Wales; 2012. [cited 2021 Jan 25].
Available from: http://handle.unsw.edu.au/1959.4/52428 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:11101/SOURCE01?view=true.
Council of Science Editors:
Philip K. Influence of ocular monochromatic aberrations in the development and/or progression of myopia. [Doctoral Dissertation]. University of New South Wales; 2012. Available from: http://handle.unsw.edu.au/1959.4/52428 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:11101/SOURCE01?view=true
University of New South Wales
10.
Chen, Xiang.
The Role Of Peripheral Refractive Errors In the Development of Myopia.
Degree: Optometry & Vision Science, 2015, University of New South Wales
URL: http://handle.unsw.edu.au/1959.4/55144
;
https://unsworks.unsw.edu.au/fapi/datastream/unsworks:36610/SOURCE02?view=true
► Aim: To investigate the relationship between peripheral retinal refractive errors and progression of refractive errors, especially myopia in terms ofspherical equivalent and axial length in…
(more)
▼ Aim: To investigate the relationship between peripheral retinal refractive errors and progression of refractive errors, especially
myopia in terms ofspherical equivalent and axial length in Chinese children.Methods: A pilot study investigated the impact of single-vision spectacle correction for their effect on peripheral refractive errors. Then, Eighty-sixhealthy Chinese children (mean age: 9.9± 0.58 yrs, 9-11 yrs) were enrolled in a longitudinal trial and screened at baseline and 6 monthly in tervalsfor 18 months. Statistical significance was set at p < 0.05.Results: The pilot study found absolute hyperopic peripheral defocus with eyes corrected with single vision spectacles. In the longitudinal study,age significantly influenced progression (younger children progressed faster than older children p=0.009). With respect to central and peripheralrefractive error profile, from baseline to 18 months, the central myopic shift was most in myopic eyes and least in hyperopic eyes (-1.34±0.27 D vs-0.49±0.14 D respectively). In the hyperopic eyes, the myopic shift was mostly central and in the temporal visual field. This resulted in thedifference between central and nasal field refractive errors increasing with time and resulting in re lative hyperopia in the nasal visual field. In themoderate myopes, the magnitude of myopic shift was similar for both central and peripheral retinal points whereas in low myopic eyes themagnitude of myopic shift was similar for central and nasal visual field.Conclusion: Absolute hyperopic peripheral defocus was found within myopic eyes corrected with single vision spectacles. It appeared that in eyesthat emmetropic and hyperopic, whilst there was a myopic shift over time, this was mostly limited to the central 20 degrees of the retina andindicative of an axial stretch ing. This predominantly central shift also resulted in hyperopic defocus at the retinal periphery. In those eyes that weremyopic eyes, over time, there was a myopic shift at both the central and peripheral retina and was suggested of a global stretching. It may be thatthe initiation of hyperopic retinal defocus at the retinal periphery possibly plays a role in the initiation of this global stretching, but the evidence isnot clear.
Advisors/Committee Members: Holden, Brien, Optometry & Vision Science, Faculty of Science, UNSW.
Subjects/Keywords: Myopia; Peripheral refractive error
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APA (6th Edition):
Chen, X. (2015). The Role Of Peripheral Refractive Errors In the Development of Myopia. (Doctoral Dissertation). University of New South Wales. Retrieved from http://handle.unsw.edu.au/1959.4/55144 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:36610/SOURCE02?view=true
Chicago Manual of Style (16th Edition):
Chen, Xiang. “The Role Of Peripheral Refractive Errors In the Development of Myopia.” 2015. Doctoral Dissertation, University of New South Wales. Accessed January 25, 2021.
http://handle.unsw.edu.au/1959.4/55144 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:36610/SOURCE02?view=true.
MLA Handbook (7th Edition):
Chen, Xiang. “The Role Of Peripheral Refractive Errors In the Development of Myopia.” 2015. Web. 25 Jan 2021.
Vancouver:
Chen X. The Role Of Peripheral Refractive Errors In the Development of Myopia. [Internet] [Doctoral dissertation]. University of New South Wales; 2015. [cited 2021 Jan 25].
Available from: http://handle.unsw.edu.au/1959.4/55144 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:36610/SOURCE02?view=true.
Council of Science Editors:
Chen X. The Role Of Peripheral Refractive Errors In the Development of Myopia. [Doctoral Dissertation]. University of New South Wales; 2015. Available from: http://handle.unsw.edu.au/1959.4/55144 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:36610/SOURCE02?view=true
University of New South Wales
11.
Fedtke, Cathleen.
Peripheral refraction: significance, current limitations and a new approach.
Degree: Optometry & Vision Science, 2011, University of New South Wales
URL: http://handle.unsw.edu.au/1959.4/51445
;
https://unsworks.unsw.edu.au/fapi/datastream/unsworks:10131/SOURCE02?view=true
► Peripheral refractive error has assumed considerable importance with the discovery that it can influence eye growth. The link between the peripheral state of the eye…
(more)
▼ Peripheral refractive error has assumed considerable importance with the discovery that it can influence eye growth. The link between the peripheral state of the eye and
myopia development demands rapid and accurate measurements at individual and population levels. Currently, the use of conventional refraction techniques requires time-consuming sequential re-alignments.The aims of this thesis were to identify and assess methodological limitations of current techniques, test new concepts and develop a method of obtaining more rapid and accurate peripheral refraction measurements.At first, the impact of pupil misalignment was investigated using a conventional autorefractor. As visual field angle increased, tolerance to pupil misalignment decreased significantly, making peripheral measurements particularly susceptible to this measurement error. It was also shown that the peripheral entrance pupil shape is not elliptical as currently assumed, adding further potential for pupil misalignment. Based on these findings, means to rectify pupil alignment-related errors when using conventional instruments were established and validated.Having ascertained limitations of current peripheral refractometry, a novel instrument concept was proposed, the EyeMapper. The EyeMapper was designed to perform a rapid peripheral (and central) refraction scan, from -50° to +50°, using 10 stationary deflecting prisms and a scanning mirror. Like most autorefractors, the operation was based on the ring-autorefraction principle. The optical design, consisting of 5 intertwined optical sub-systems was developed. Safety aspects and criteria for instrument components were assessed and the operation principle was verified experimentally. Experimental testing identified an obstacle relating to the ring-image analysis and it revealed that peripheral higher order aberrations have the potential to interfere with the sphero-cylindrical refraction readings obtained when applying this ring-autorefraction principle. A technique that segregates higher and lower order aberrations was thus deemed more suitable for measuring peripheral refraction. Hence, the EyeMapper design was updated to include wavefront measurements. The prototype instrument was then built and experimentally tested over a range of refractive errors. The EyeMapper uses an array of beam steering mirrors and a scanning mirror to perform a rapid peripheral refraction scan in one meridian. Three-dimensional power maps of the eye can be obtained by pivoting the instrument around its optical axis.
Advisors/Committee Members: Holden, Brien, Brien Holden Vision Institute, Ehrmann, Klaus, Brien Holden Vision Institute.
Subjects/Keywords: Myopia; Peripheral refraction; Instrumentation
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APA (6th Edition):
Fedtke, C. (2011). Peripheral refraction: significance, current limitations and a new approach. (Doctoral Dissertation). University of New South Wales. Retrieved from http://handle.unsw.edu.au/1959.4/51445 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:10131/SOURCE02?view=true
Chicago Manual of Style (16th Edition):
Fedtke, Cathleen. “Peripheral refraction: significance, current limitations and a new approach.” 2011. Doctoral Dissertation, University of New South Wales. Accessed January 25, 2021.
http://handle.unsw.edu.au/1959.4/51445 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:10131/SOURCE02?view=true.
MLA Handbook (7th Edition):
Fedtke, Cathleen. “Peripheral refraction: significance, current limitations and a new approach.” 2011. Web. 25 Jan 2021.
Vancouver:
Fedtke C. Peripheral refraction: significance, current limitations and a new approach. [Internet] [Doctoral dissertation]. University of New South Wales; 2011. [cited 2021 Jan 25].
Available from: http://handle.unsw.edu.au/1959.4/51445 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:10131/SOURCE02?view=true.
Council of Science Editors:
Fedtke C. Peripheral refraction: significance, current limitations and a new approach. [Doctoral Dissertation]. University of New South Wales; 2011. Available from: http://handle.unsw.edu.au/1959.4/51445 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:10131/SOURCE02?view=true
University of New South Wales
12.
Kang, Pauline.
Peripheral refraction: relationship to myopia, and manipulation using contact lenses.
Degree: Optometry & Vision Science, 2012, University of New South Wales
URL: http://handle.unsw.edu.au/1959.4/51691
;
https://unsworks.unsw.edu.au/fapi/datastream/unsworks:10358/SOURCE02?view=true
► The aims of this thesis were to investigate peripheral refraction in different refractive groups and verify the use of peripheral refraction as a measure of…
(more)
▼ The aims of this thesis were to investigate peripheral refraction in different refractive groups and verify the use of peripheral refraction as a measure of ocular shape. Furthermore, manipulation of peripheral refraction with orthokeratology (OK) and soft contact lenses (SCLs) for potential
myopia control were explored. Characteristic peripheral refraction profiles were measured using the Shin-Nippon NVision-K 5001 autorefractor in emmetropes (relative peripheral
myopia) and myopes (relative peripheral hyperopia). East Asian moderate myopes had greater amounts of relative peripheral hyperopia compared to Caucasians with a similar central refractive error. This was interpreted to reflect a more prolate ocular shape in the myopic Asian eye.Calculated axial length from peripheral refraction was found to comparable to direct axial length measurements with the IOLMaster in the nasal retina and to underestimate axial length in the temporal retina. Although not entirely comparable, peripheral refraction is still able to give information on the shape of eyes with different refractive errors.Conventional corrections of central
myopia induce hyperopia onto the peripheral retina. However, OK lenses were found to cause a hyperopic shift in the central visual field (VF) in both myopic children and adults. This caused peripheral refraction which was initially relatively hyperopic to become relatively myopic compared to the central refraction. Furthermore, changing the optic zone diameter or steepening the periphery of the OK lens was found to cause no significant effect. Relative hyperopic peripheral refraction was measured along the horizontal VF with under (+0.75DS), full, over (-0.75DS) SCL correction and multifocal SCLs with a distance centre and plus power (+2.00) periphery were found to induce less peripheral hyperopia compared to single vision (SV) SCL correction. OK allows the peripheral retina to experience myopic defocus while central
myopia is corrected, and multifocal SCLs are able to reduce the amount of relative peripheral hyperopia compared to SV SCLs. This may explain the reduced
myopia progression reported with OK and multifocal SCLs. The effects of manipulating other OK lens parameters for potential customised
myopia control are yet to be explored, and the impact of myopic peripheral defocus on
myopia progression in children is yet to be ascertained.
Advisors/Committee Members: Swarbrick, Helen, Optometry & Vision Science, Faculty of Science, UNSW, Pye, David, Optometry & Vision Science, Faculty of Science, UNSW.
Subjects/Keywords: Contact lenses; Peripheral refraction; Myopia
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APA (6th Edition):
Kang, P. (2012). Peripheral refraction: relationship to myopia, and manipulation using contact lenses. (Doctoral Dissertation). University of New South Wales. Retrieved from http://handle.unsw.edu.au/1959.4/51691 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:10358/SOURCE02?view=true
Chicago Manual of Style (16th Edition):
Kang, Pauline. “Peripheral refraction: relationship to myopia, and manipulation using contact lenses.” 2012. Doctoral Dissertation, University of New South Wales. Accessed January 25, 2021.
http://handle.unsw.edu.au/1959.4/51691 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:10358/SOURCE02?view=true.
MLA Handbook (7th Edition):
Kang, Pauline. “Peripheral refraction: relationship to myopia, and manipulation using contact lenses.” 2012. Web. 25 Jan 2021.
Vancouver:
Kang P. Peripheral refraction: relationship to myopia, and manipulation using contact lenses. [Internet] [Doctoral dissertation]. University of New South Wales; 2012. [cited 2021 Jan 25].
Available from: http://handle.unsw.edu.au/1959.4/51691 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:10358/SOURCE02?view=true.
Council of Science Editors:
Kang P. Peripheral refraction: relationship to myopia, and manipulation using contact lenses. [Doctoral Dissertation]. University of New South Wales; 2012. Available from: http://handle.unsw.edu.au/1959.4/51691 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:10358/SOURCE02?view=true
University of Houston
13.
Nourani-Dargiri, Sara.
Lamina Cribrosa and Optic Nerve Head Geometry as a Function of Myopia in Older Normal Eyes.
Degree: MS, Physiological Optics and Vision Science, 2017, University of Houston
URL: http://hdl.handle.net/10657/4812
► Purpose: Increased age and levels of myopia are potential risk factors for the development of glaucoma. However, their impact on optic nerve head (ONH) structure…
(more)
▼ Purpose: Increased age and levels of
myopia are potential risk factors for the development of glaucoma. However, their impact on optic nerve head (ONH) structure in normal eyes has not been fully described. We examined whether differences exist in ONH and lamina cribrosa structure with
myopia in older normal eyes.
Methods: Spectral domain optical coherence tomography (SDOCT) scans centered on the ONH were acquired in one eye of 15 older normal subjects (mean = 58.1 ± 7.4 years) with high
myopia (spherical equivalent [SE] ≤ -6.00 D) and 16 older normal subjects (mean = 57.5 ± 6.8 years) with emmetropia to moderate
myopia (SE = plano to -6.00 D). Retinal nerve fiber layer thickness (RNFLT) was quantified from 12° circular scans. ONH features were marked in each of 48 radial B-scans (20° field) using a semi-automated MATLAB program to calculate Bruch’s Membrane Opening (BMO) area and circumference, mean anterior lamina cribrosa surface depth (ALCSD), mean minimum rim width (MRW) and mean scaled MRW.
Results: Refractive errors and axial lengths (ALs) in highly myopic eyes (mean SE = -7.18 ± 1.17 D; mean AL = 26.41 ± 0.76 mm) were statistically different from emmetropic/low myopic eyes (mean SE = -1.59 ± 1.63 D; mean AL = 24.92 ± 1.06 mm) (P<.01). While RNFLT was thinner in older eyes with high
myopia (85.5 ± 7.7 μm) compared to those with emmetropia/low
myopia (99.2 ± 5.0 μm; P<.01), no significant differences were measured in other ONH parameters between groups. Mean MRW was significantly thinner in highly myopic eyes with larger BMO areas (P=.04) and tended to be thinner in eyes with more posteriorly-located ALCS’s (P=.09). Conversely, no significant relationships were found between MRW and ALCSD (P=.60) or BMO area (P=.54) in older eyes with emmetropia/low
myopia.
Conclusion: The tendency for mean MRW to be thinner in highly myopic eyes with more posteriorly-located ALCS’s and larger BMO areas could indicate that axons are pulled toward the BMO in eyes with a deeper lamina. This anatomical configuration may increase the biomechanical susceptibility for glaucomatous axonal damage in older, highly myopic eyes.
Advisors/Committee Members: Porter, Jason (advisor), Harwerth, Ronald S. (committee member), Marrelli, Danica J. (committee member), Ostrin, Lisa A. (committee member).
Subjects/Keywords: Myopia; Glaucoma; Glaucoma imaging; High myopia; Lamina cribrosa; Minimum rim width
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APA (6th Edition):
Nourani-Dargiri, S. (2017). Lamina Cribrosa and Optic Nerve Head Geometry as a Function of Myopia in Older Normal Eyes. (Masters Thesis). University of Houston. Retrieved from http://hdl.handle.net/10657/4812
Chicago Manual of Style (16th Edition):
Nourani-Dargiri, Sara. “Lamina Cribrosa and Optic Nerve Head Geometry as a Function of Myopia in Older Normal Eyes.” 2017. Masters Thesis, University of Houston. Accessed January 25, 2021.
http://hdl.handle.net/10657/4812.
MLA Handbook (7th Edition):
Nourani-Dargiri, Sara. “Lamina Cribrosa and Optic Nerve Head Geometry as a Function of Myopia in Older Normal Eyes.” 2017. Web. 25 Jan 2021.
Vancouver:
Nourani-Dargiri S. Lamina Cribrosa and Optic Nerve Head Geometry as a Function of Myopia in Older Normal Eyes. [Internet] [Masters thesis]. University of Houston; 2017. [cited 2021 Jan 25].
Available from: http://hdl.handle.net/10657/4812.
Council of Science Editors:
Nourani-Dargiri S. Lamina Cribrosa and Optic Nerve Head Geometry as a Function of Myopia in Older Normal Eyes. [Masters Thesis]. University of Houston; 2017. Available from: http://hdl.handle.net/10657/4812
University of Debrecen
14.
Szatmári, György.
Kontaktlencse viselés és szövődményei
.
Degree: DE – Általános Orvostudományi Kar, University of Debrecen
URL: http://hdl.handle.net/2437/273711
► A myopia napjaink egyik legfontosabb látással kapcsolatos problémája. A súlyos myopia számos szövődményhez vezethet, ha kezeletlen marad. A myopia jelentősége miatt a dolgozat magában foglalja…
(more)
▼ A
myopia napjaink egyik legfontosabb látással kapcsolatos problémája. A súlyos
myopia számos szövődményhez vezethet, ha kezeletlen marad. A
myopia jelentősége miatt a dolgozat magában foglalja a
myopia és a
myopia progresszió rövid leírását és rizikófaktorait. Az orthokeratológiai lencsék formálják a cornea felszínét, amely így
myopia progresszió csökkentésére alkalmazható alacsony szövődményi rátával. A dolgozat az orthokeratológia történetének, mechanizmusának, lencseillesztési elveinek és szövődményeinek részletesebb tárgyalását is magában foglalja. Továbbá a klinikán orthokeratológiai kezelésben részesült betegek nem és dioptria alapján történő összehasonlítását, valamint az adatok más irodalmi adatokkal való összevetését is tárgyalja.
Advisors/Committee Members: Kettesy, Andrea Beáta (advisor), Debreceni Egyetem::Általános Orvostudományi Kar::Szemklinika (advisor).
Subjects/Keywords: orthokeratológia;
myopia;
kontaktlencse;
myopia progresszió
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APA (6th Edition):
Szatmári, G. (n.d.). Kontaktlencse viselés és szövődményei
. (Thesis). University of Debrecen. Retrieved from http://hdl.handle.net/2437/273711
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Szatmári, György. “Kontaktlencse viselés és szövődményei
.” Thesis, University of Debrecen. Accessed January 25, 2021.
http://hdl.handle.net/2437/273711.
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Szatmári, György. “Kontaktlencse viselés és szövődményei
.” Web. 25 Jan 2021.
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Vancouver:
Szatmári G. Kontaktlencse viselés és szövődményei
. [Internet] [Thesis]. University of Debrecen; [cited 2021 Jan 25].
Available from: http://hdl.handle.net/2437/273711.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.
Council of Science Editors:
Szatmári G. Kontaktlencse viselés és szövődményei
. [Thesis]. University of Debrecen; Available from: http://hdl.handle.net/2437/273711
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.
University of Wisconsin – La Cross
15.
Berg, Christina M.
Myopia Education 101: A Holistic Journey to Understanding Myopia Development, Natural Improvement, and Prevention Strategies.
Degree: 2000, University of Wisconsin – La Cross
URL: http://digital.library.wisc.edu/1793/48367
Subjects/Keywords: Self-care, Health; Myopia - Prevention; Myopia - Treatment; Myopia
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APA (6th Edition):
Berg, C. M. (2000). Myopia Education 101: A Holistic Journey to Understanding Myopia Development, Natural Improvement, and Prevention Strategies. (Thesis). University of Wisconsin – La Cross. Retrieved from http://digital.library.wisc.edu/1793/48367
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Berg, Christina M. “Myopia Education 101: A Holistic Journey to Understanding Myopia Development, Natural Improvement, and Prevention Strategies.” 2000. Thesis, University of Wisconsin – La Cross. Accessed January 25, 2021.
http://digital.library.wisc.edu/1793/48367.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Berg, Christina M. “Myopia Education 101: A Holistic Journey to Understanding Myopia Development, Natural Improvement, and Prevention Strategies.” 2000. Web. 25 Jan 2021.
Vancouver:
Berg CM. Myopia Education 101: A Holistic Journey to Understanding Myopia Development, Natural Improvement, and Prevention Strategies. [Internet] [Thesis]. University of Wisconsin – La Cross; 2000. [cited 2021 Jan 25].
Available from: http://digital.library.wisc.edu/1793/48367.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Berg CM. Myopia Education 101: A Holistic Journey to Understanding Myopia Development, Natural Improvement, and Prevention Strategies. [Thesis]. University of Wisconsin – La Cross; 2000. Available from: http://digital.library.wisc.edu/1793/48367
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Johannesburg
16.
Ramkissoon, Prithipaul.
A clinical evaluation of overnight orthokeratology as a method of vision correction.
Degree: 2014, University of Johannesburg
URL: http://hdl.handle.net/10210/12293
D.Phil. (Optometry)
Please refer to full text to view abstract
Subjects/Keywords: Orthokeratology; Myopia - Treatment
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APA (6th Edition):
Ramkissoon, P. (2014). A clinical evaluation of overnight orthokeratology as a method of vision correction. (Thesis). University of Johannesburg. Retrieved from http://hdl.handle.net/10210/12293
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Ramkissoon, Prithipaul. “A clinical evaluation of overnight orthokeratology as a method of vision correction.” 2014. Thesis, University of Johannesburg. Accessed January 25, 2021.
http://hdl.handle.net/10210/12293.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Ramkissoon, Prithipaul. “A clinical evaluation of overnight orthokeratology as a method of vision correction.” 2014. Web. 25 Jan 2021.
Vancouver:
Ramkissoon P. A clinical evaluation of overnight orthokeratology as a method of vision correction. [Internet] [Thesis]. University of Johannesburg; 2014. [cited 2021 Jan 25].
Available from: http://hdl.handle.net/10210/12293.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Ramkissoon P. A clinical evaluation of overnight orthokeratology as a method of vision correction. [Thesis]. University of Johannesburg; 2014. Available from: http://hdl.handle.net/10210/12293
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Queensland University of Technology
17.
Cheng, Desmond.
Bifocal lens control of myopia progression in children.
Degree: 2008, Queensland University of Technology
URL: https://eprints.qut.edu.au/29688/
► This research investigated underlying issues that were critical to the success of the bifocal trial and comprised of three studies. The first study evaluated if…
(more)
▼ This research investigated underlying issues that were critical to the success of the bifocal trial and comprised of three studies. The first study evaluated if Chinese-Canadian children were suitable subjects for the bifocal trial. The high prevalence of myopia in Chinese children suggests that genetic input plays a role in myopia development, but the rapid increase in prevalence over the last few decades indicates environmental factors are also important. Since this bifocal trial was conducted in Canada, this work aimed to determine whether Chinese children who had migrated to Canada would still have high myopia prevalence and a high rate of myopia progression. The second study determined the optimal bifocal lens power for myopia treatment and the effect of incorporating base-in prism into the bifocal. In the majority of published myopia control studies, the power of the prescribed near addition was usually predetermined in the belief that the near addition would always help to improve the near focus. In fact, the effect of near addition on the accommodative error might be quite different even for individuals in which the same magnitude of accommodation lag had been measured. Therefore, this work was necessary to guide the selection of bifocal and prism powers most suitable for the subsequent bifocal trial. The third study, the ultimate goal of this research, was to conduct a longitudinal clinical trial to determine if bifocals and prismatic bifocals could control myopia progression in children.
Subjects/Keywords: children; Chinese; myopia; prevalence; accommodation; bifocal; phoria
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APA (6th Edition):
Cheng, D. (2008). Bifocal lens control of myopia progression in children. (Thesis). Queensland University of Technology. Retrieved from https://eprints.qut.edu.au/29688/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Cheng, Desmond. “Bifocal lens control of myopia progression in children.” 2008. Thesis, Queensland University of Technology. Accessed January 25, 2021.
https://eprints.qut.edu.au/29688/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Cheng, Desmond. “Bifocal lens control of myopia progression in children.” 2008. Web. 25 Jan 2021.
Vancouver:
Cheng D. Bifocal lens control of myopia progression in children. [Internet] [Thesis]. Queensland University of Technology; 2008. [cited 2021 Jan 25].
Available from: https://eprints.qut.edu.au/29688/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Cheng D. Bifocal lens control of myopia progression in children. [Thesis]. Queensland University of Technology; 2008. Available from: https://eprints.qut.edu.au/29688/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Queensland University of Technology
18.
Vincent, Stephen James.
Ocular characteristics of anisometropia.
Degree: 2011, Queensland University of Technology
URL: https://eprints.qut.edu.au/47531/
► Animal models of refractive error development have demonstrated that visual experience influences ocular growth. In a variety of species, axial anisometropia (i.e. a difference in…
(more)
▼ Animal models of refractive error development have demonstrated that visual experience influences ocular growth. In a variety of species, axial anisometropia (i.e. a difference in the length of the two eyes) can be induced through unilateral occlusion, image degradation or optical manipulation. In humans, anisometropia may occur in isolation or in association with amblyopia, strabismus or unilateral pathology. Non-amblyopic myopic anisometropia represents an interesting anomaly of ocular growth, since the two eyes within one visual system have grown to different endpoints. These experiments have investigated a range of biometric, optical and mechanical properties of anisometropic eyes (with and without amblyopia) with the aim of improving our current understanding of asymmetric refractive error development.
In the first experiment, the interocular symmetry in 34 non-amblyopic myopic anisometropes (31 Asian, 3 Caucasian) was examined during relaxed accommodation. A high degree of symmetry was observed between the fellow eyes for a range of optical, biometric and biomechanical measurements. When the magnitude of anisometropia exceeded 1.75 D, the more myopic eye was almost always the sighting dominant eye. Further analysis of the optical and biometric properties of the dominant and non-dominant eyes was conducted to determine any related factors but no significant interocular differences were observed with respect to best-corrected visual acuity, corneal or total ocular aberrations during relaxed accommodation.
Given the high degree of symmetry observed between the fellow eyes during distance viewing in the first experiment and the strong association previously reported between near work and myopia development, the aim of the second experiment was to investigate the symmetry between the fellow eyes of the same 34 myopic anisometropes following a period of near work. Symmetrical changes in corneal and total ocular aberrations were observed following a short reading task (10 minutes, 2.5 D accommodation demand) which was attributed to the high degree of interocular symmetry for measures of anterior eye morphology, and corneal biomechanics. These changes were related to eyelid shape and position during downward gaze, but gave no clear indication of factors associated with near work that might cause asymmetric eye growth within an individual.
Since the influence of near work on eye growth is likely to be most obvious during, rather than following near tasks, in the third experiment the interocular symmetry of the optical and biometric changes was examined during accommodation for 11 myopic anisometropes. The changes in anterior eye biometrics associated with accommodation were again similar between the eyes, resulting in symmetrical changes in the optical characteristics. However, the more myopic eyes exhibited slightly greater amounts of axial elongation during accommodation which may be related to the force exerted by the ciliary muscle. This small asymmetry in axial elongation we observed between…
Subjects/Keywords: anisometropia; myopia; asymmetry; amblyopia; aberrations; dominance; ODTA
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APA (6th Edition):
Vincent, S. J. (2011). Ocular characteristics of anisometropia. (Thesis). Queensland University of Technology. Retrieved from https://eprints.qut.edu.au/47531/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Vincent, Stephen James. “Ocular characteristics of anisometropia.” 2011. Thesis, Queensland University of Technology. Accessed January 25, 2021.
https://eprints.qut.edu.au/47531/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Vincent, Stephen James. “Ocular characteristics of anisometropia.” 2011. Web. 25 Jan 2021.
Vancouver:
Vincent SJ. Ocular characteristics of anisometropia. [Internet] [Thesis]. Queensland University of Technology; 2011. [cited 2021 Jan 25].
Available from: https://eprints.qut.edu.au/47531/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Vincent SJ. Ocular characteristics of anisometropia. [Thesis]. Queensland University of Technology; 2011. Available from: https://eprints.qut.edu.au/47531/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Houston
19.
Burfield, Hannah.
Ocular and Systemic Diurnal Rhythms in Emmetropic and Myopic Adults.
Degree: MS, Physiological Optics and Vision Science, 2019, University of Houston
URL: http://hdl.handle.net/10657/4663
► Purpose: Evidence suggests that diurnal rhythms and light exposure patterns may influence the development of refractive error. This study investigated diurnal variations in anterior and…
(more)
▼ Purpose: Evidence suggests that diurnal rhythms and light exposure patterns may influence the development of refractive error. This study investigated diurnal variations in anterior and posterior segment biometry and assessed differences between myopic and emmetropic adults. Ocular and systemic diurnal rhythms were also examined in relation to objectively measured light exposure and refractive error.
Methods: Healthy subjects (n = 42, 23-41 years old) underwent biometry and spectral domain optical coherence tomography imaging (SD-OCT) every 4 hours (h) for 24 h. Subjects were in darkness from 11:00 pm to 7:00 am. Central corneal thickness, corneal power, anterior chamber depth, lens thickness, vitreous chamber depth, and axial length were measured. Thicknesses of the total retina, photoreceptor outer segments + retinal pigment epithelium (RPE), photoreceptor inner segments, and choroid for a 3mm and 6mm annulus were determined. Additional measurements taken at each time point included blood pressure, heart rate, body temperature, and intraocular pressure (IOP). Mean ocular perfusion pressure (MOPP) was calculated. Saliva was collected for melatonin and cortisol analysis. Subjects wore a light, sleep, and activity monitor for one week prior to measurements. Acrophase and amplitude for each parameter were compared between refractive error groups and relationship to light exposure was examined.
Results: All ocular and systemic parameters except anterior chamber depth demonstrated significant diurnal variations. Amplitude of axial length variation (35.71 ± 19.40 μm) was in antiphase to choroid variation (25.65 ± 2.01 μm, P < 0.001). The central 1 mm retina underwent variation of 5.03 ± 0.23 μm with a peak at 12 h (p < 0.001), while photoreceptor outer segment + RPE thickness peaked at 4 h and inner segment thickness peaked at 16 h. Diurnal variations in retina and choroid were observed in the 3 and 6 mm annuli. Melatonin increased following light offset with a peak at 3.19 h, while cortisol peaked after light onset at 8.86 h. IOP peaked at 11.24 h, with a variation of 4.92 ± 1.57 of mmHg, in anti-phase with MOPP, which peaked at 22.02 h. No parameter demonstrated a difference in diurnal rhythm between refractive error groups except for body temperature and MOPP.
Conclusion: Ocular and systemic diurnal rhythms were observed over 24 hours in adults. While differences in baseline parameters were found between refractive error groups, diurnal rhythms were not significantly different between myopes and emmetropes, except for body temperature and MOPP. Amplitudes of daily variations were not correlated with light exposure.
Advisors/Committee Members: Ostrin, Lisa A. (advisor), Berntsen, David A. (committee member), Patel, Nimesh B. (committee member).
Subjects/Keywords: Myopia; Circadian rhythm; Choroid; Ocular biometry
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APA (6th Edition):
Burfield, H. (2019). Ocular and Systemic Diurnal Rhythms in Emmetropic and Myopic Adults. (Masters Thesis). University of Houston. Retrieved from http://hdl.handle.net/10657/4663
Chicago Manual of Style (16th Edition):
Burfield, Hannah. “Ocular and Systemic Diurnal Rhythms in Emmetropic and Myopic Adults.” 2019. Masters Thesis, University of Houston. Accessed January 25, 2021.
http://hdl.handle.net/10657/4663.
MLA Handbook (7th Edition):
Burfield, Hannah. “Ocular and Systemic Diurnal Rhythms in Emmetropic and Myopic Adults.” 2019. Web. 25 Jan 2021.
Vancouver:
Burfield H. Ocular and Systemic Diurnal Rhythms in Emmetropic and Myopic Adults. [Internet] [Masters thesis]. University of Houston; 2019. [cited 2021 Jan 25].
Available from: http://hdl.handle.net/10657/4663.
Council of Science Editors:
Burfield H. Ocular and Systemic Diurnal Rhythms in Emmetropic and Myopic Adults. [Masters Thesis]. University of Houston; 2019. Available from: http://hdl.handle.net/10657/4663
20.
Shorrock, Heather.
Optical, neural and perceptual basis of blur sensitivity and the effect of text detail in myopes and emmetropes.
Degree: PhD, 2013, Anglia Ruskin University
URL: http://arro.anglia.ac.uk/id/eprint/305407/
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.582769
► Retinal blur experienced by myopes during near work has been linked to myopia development and progression. Whether poor responses to blur signals are due to…
(more)
▼ Retinal blur experienced by myopes during near work has been linked to myopia development and progression. Whether poor responses to blur signals are due to poor perceptual blur sensitivity (subjective depth of focus), poor neural accommodation responses (objective depth of focus) to blur or optical differences such as higher order aberrations making blur detection difficult is yet unclear. This study investigates whether myopes respond to blur differently compared to emmetropes and whether filtering spatial frequencies in reading text influence accommodation responses. Accommodative functions were investigated using spatial frequency filtered text targets of two different sizes (N10 and N20). Monocular objective depth of focus (DOF), accommodative microfluctuations, and dynamic accommodation were measured. Subjective DOF after cycloplegia was also recorded with the same targets. Higher order aberration measurements explored optical contributions to blur. Peripheral refraction and accommodative lag were also measured to consider how in combination they might increase peripheral retinal blur for near tasks. Results showed that myopes demonstrated larger subjective DOF. Subjective DOF was larger when viewing the peak text spatial frequency in both refractive error groups. The optimum focus was more myopic for text peak spatial frequencies. Levels of spherical aberration were correlated with the point of optimum focus. Objective DOF and accommodative microfluctuations were larger in myopes when viewing the peak text spatial frequencies. Dynamic accommodation showed that while myopes were not poorer at initiating accommodation responses they had longer positive response times. Accommodative lag, although not different in myopes, increases the peripheral hyperopic blur experienced for near tasks. Conclusion: Myopes were poorer at using retinal blur cues to refine accommodation responses especially when viewing peak text spatial frequencies. Larger positive response times, DOF and accommodative microfluctuations in myopes resulted in accommodative error and hyperopic blur for near tasks. Spherical aberration, previously thought to provide a myopigenic stimulus, was not different between refractive groups and is unlikely to be large enough to enhance DOF during naturalistic viewing. Blur adaptation studies might consider using peak text spatial frequencies as adaptation targets to reduce accommodation differences in myopes and emmetropes. Optical treatment strategies aimed at correcting peripheral refraction to control myopia should consider the combined effect of accommodative lag which increases levels of hyperopic peripheral blur experienced by myopes.
Subjects/Keywords: 617.7; myopia; blur sensitivity; spatial frequency; accomodation
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APA (6th Edition):
Shorrock, H. (2013). Optical, neural and perceptual basis of blur sensitivity and the effect of text detail in myopes and emmetropes. (Doctoral Dissertation). Anglia Ruskin University. Retrieved from http://arro.anglia.ac.uk/id/eprint/305407/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.582769
Chicago Manual of Style (16th Edition):
Shorrock, Heather. “Optical, neural and perceptual basis of blur sensitivity and the effect of text detail in myopes and emmetropes.” 2013. Doctoral Dissertation, Anglia Ruskin University. Accessed January 25, 2021.
http://arro.anglia.ac.uk/id/eprint/305407/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.582769.
MLA Handbook (7th Edition):
Shorrock, Heather. “Optical, neural and perceptual basis of blur sensitivity and the effect of text detail in myopes and emmetropes.” 2013. Web. 25 Jan 2021.
Vancouver:
Shorrock H. Optical, neural and perceptual basis of blur sensitivity and the effect of text detail in myopes and emmetropes. [Internet] [Doctoral dissertation]. Anglia Ruskin University; 2013. [cited 2021 Jan 25].
Available from: http://arro.anglia.ac.uk/id/eprint/305407/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.582769.
Council of Science Editors:
Shorrock H. Optical, neural and perceptual basis of blur sensitivity and the effect of text detail in myopes and emmetropes. [Doctoral Dissertation]. Anglia Ruskin University; 2013. Available from: http://arro.anglia.ac.uk/id/eprint/305407/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.582769
University of Newcastle
21.
Fuchs, Dominique Lena.
Influence of lens induced myopia on retinal gene expression in the guinea pig.
Degree: PhD, 2019, University of Newcastle
URL: http://hdl.handle.net/1959.13/1408615
► Research Doctorate - Doctor of Philosophy (PhD)
Myopia is a refractive error characterized by an abnormal increase in eye length. The prevalence of myopia is…
(more)
▼ Research Doctorate - Doctor of Philosophy (PhD)
Myopia is a refractive error characterized by an abnormal increase in eye length. The prevalence of myopia is increasing in a global manner and the increase in humans affected by myopia comes along with an increasing number of patients affected with high myopia (more than -6D). High myopia is associated with serious complications including retinal detachment, glaucoma and posterior staphyloma. Ocular development depends on visual experience. Myopia can be induced in animal eyes by rearing them with negative spectacle lenses which displaces the focal point behind the retina. The eye compensates for this imposed defocus by elongating more rapidly. Such visual manipulations enable the exploration of the so far poorly understood underlying biological mechanisms of myopia development. Myopia development is associated with transcription changes and physical changes in ocular tissues. This thesis focusses on the exploration of mRNA expression changes in the guinea pig retina that accompany changes in axial elongation. Therefore, myopic and non-myopic guinea pig retinas were compared via the high throughput method of RNA sequencing (RNA-seq). RNA-seq was used to compare normal retinal samples from untreated age-matched guinea pigs with those from guinea pigs that developed myopia over 4 or 11 days, and with samples originating from eyes that had recovered for 48 hours from the induced myopia. The RNA-seq results were analysed with 4 different downstream analysis tools (Voom, DESeq2, EdgeR and Cuffdiff) to determine differentially expressed genes (DEG’s). The results from the tools Cuffdiff were used for pathway analysis. Expression analysis with Cuffdiff resulted in 137 DEG’s after 4 days of myopia development, 98 DEG’s after 11 days of myopia development and 47 DEG’s after 48h of recovery from myopia development. Retinol binding protein 1 was significantly upregulated according to the corrected p-value in all 3 comparisons. Several of the DEG’s (FAM107A, Col4A4, ApoE, MMP-2, and RBP1) were successfully validated using quantitative real time polymerase chain reaction (qPCR). Some of the DEG’s after induced myopia which were determined by Cuffdiff are well known to play a role in scleral remodelling during myopia development: Bone morphogenetic protein 2, Metalloproteinase 1 (MMP-2) and collagens. MMP-2 was significantly upregulated after 11 days of myopia development, BMP-2 after 4 days of myopia development and a number of collagens were upregulated in both conditions. Pathway analysis revealed that the pathways RAR activation and Retinol biosynthesis were among the top 10 associated pathways after 4 days of myopia development and after 48h of recovery from myopia development. Another pathway related to Vitamin A metabolism, Retinoate biosynthesis, was among the top 10 associated pathways after 4 days of myopia development. Other significant top associated pathways after 4 days of induced myopia were related to eukaryotic translation initiation and regulation (EIF2…
Advisors/Committee Members: University of Newcastle. Faculty of Science, School of Psychology.
Subjects/Keywords: myopia; gene expression; pathway analysis; retinol biosynthesis
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APA (6th Edition):
Fuchs, D. L. (2019). Influence of lens induced myopia on retinal gene expression in the guinea pig. (Doctoral Dissertation). University of Newcastle. Retrieved from http://hdl.handle.net/1959.13/1408615
Chicago Manual of Style (16th Edition):
Fuchs, Dominique Lena. “Influence of lens induced myopia on retinal gene expression in the guinea pig.” 2019. Doctoral Dissertation, University of Newcastle. Accessed January 25, 2021.
http://hdl.handle.net/1959.13/1408615.
MLA Handbook (7th Edition):
Fuchs, Dominique Lena. “Influence of lens induced myopia on retinal gene expression in the guinea pig.” 2019. Web. 25 Jan 2021.
Vancouver:
Fuchs DL. Influence of lens induced myopia on retinal gene expression in the guinea pig. [Internet] [Doctoral dissertation]. University of Newcastle; 2019. [cited 2021 Jan 25].
Available from: http://hdl.handle.net/1959.13/1408615.
Council of Science Editors:
Fuchs DL. Influence of lens induced myopia on retinal gene expression in the guinea pig. [Doctoral Dissertation]. University of Newcastle; 2019. Available from: http://hdl.handle.net/1959.13/1408615
University of Newcastle
22.
Bowrey, Hannah.
Investigation of the cues underlying myopia and their association with retinal neuronal nitric oxide synthase in the guinea pig eye.
Degree: PhD, 2015, University of Newcastle
URL: http://hdl.handle.net/1959.13/1059900
► Research Doctorate - Doctor of Philosophy (PhD)
Background and Aims. Myopia occurs when distant objects are imaged in front of the retina and thus appear…
(more)
▼ Research Doctorate - Doctor of Philosophy (PhD)
Background and Aims. Myopia occurs when distant objects are imaged in front of the retina and thus appear blurred. It typically develops if the growth of the eye is too great for its decreasing optical power during emmetropisation. High myopia is associated with serious ocular disease and is recognised as a leading cause of vision impairment globally. The cause(s) of the extraordinary increases in the prevalence of myopia, particularly in East Asia, are unknown. Animal models have demonstrated that myopia can be induced by depriving the eye of visual detail (form deprivation, FD) and when retinal defocus is imposed with lenses. Exposure to high light levels or outdoor activity can slow or delay the onset of myopia, suggesting retinal light signals may be involved. An important light signal present in the retina is nitric oxide (NO). NO is critically involved in light adaptation and its related enzyme, neuronal NO synthase (nNOS), is an important mediator of the choroidal response to myopia recovery in the chick. In the mammalian retina, the expression of nNOS in the guinea pig eye is changed in opposite directions depending on the direction of ocular growth. The guinea pig provides a useful mammalian model of myopia, due to a rapid response to both FD and lensimposed defocus. In this thesis, these paradigms were extended to further investigate the association between retinal nNOS and features underlying myopia.
Advisors/Committee Members: University of Newcastle. Faculty of Science & Information Technology, School of Psychology.
Subjects/Keywords: myopia; retinal nNOS; ocular disease; vision impairment
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APA (6th Edition):
Bowrey, H. (2015). Investigation of the cues underlying myopia and their association with retinal neuronal nitric oxide synthase in the guinea pig eye. (Doctoral Dissertation). University of Newcastle. Retrieved from http://hdl.handle.net/1959.13/1059900
Chicago Manual of Style (16th Edition):
Bowrey, Hannah. “Investigation of the cues underlying myopia and their association with retinal neuronal nitric oxide synthase in the guinea pig eye.” 2015. Doctoral Dissertation, University of Newcastle. Accessed January 25, 2021.
http://hdl.handle.net/1959.13/1059900.
MLA Handbook (7th Edition):
Bowrey, Hannah. “Investigation of the cues underlying myopia and their association with retinal neuronal nitric oxide synthase in the guinea pig eye.” 2015. Web. 25 Jan 2021.
Vancouver:
Bowrey H. Investigation of the cues underlying myopia and their association with retinal neuronal nitric oxide synthase in the guinea pig eye. [Internet] [Doctoral dissertation]. University of Newcastle; 2015. [cited 2021 Jan 25].
Available from: http://hdl.handle.net/1959.13/1059900.
Council of Science Editors:
Bowrey H. Investigation of the cues underlying myopia and their association with retinal neuronal nitric oxide synthase in the guinea pig eye. [Doctoral Dissertation]. University of Newcastle; 2015. Available from: http://hdl.handle.net/1959.13/1059900
University of Melbourne
23.
SRINIVASALU, NETHRAJEITH.
Cellular biomechanics of the sclera: role of strain on cell-mediated extracellular matrix contraction and cellular differentiation.
Degree: 2010, University of Melbourne
URL: http://hdl.handle.net/11343/35666
► Myopia is a refractive error characterised by an abnormal increase in eye size. The sclera, a structure that maintains ocular integrity, is responsible for controlling…
(more)
▼ Myopia is a refractive error characterised by an abnormal increase in eye size. The sclera, a structure that maintains ocular integrity, is responsible for controlling eye size and hence is a potential target for myopia control. Active remodelling of the scleral extracellular matrix during myopia has been believed to alter the tissue’s biomechanical properties and result in ocular elongation. However, studies carried out in other connective tissues have demonstrated a possible role for the α-smooth muscle actin (α-SMA) expressing myofibroblasts in contributing to the tissue biomechanics. The effect of myofibroblasts at contributing to tissue biomechanics is further mediated by the stresses affecting the surrounding matrix. As the sclera contains a resident myofibroblast population and is under constant yet varying strain during eye growth and myopia, this study aimed to identify the effect of matrix strain in mediating matrix contraction and scleral myofibroblast differentiation.
The first experiment demonstrated the role of cellular strain (intrinsic and applied) in mediating contraction of the in vitro scleral cell-populated matrix. Increasing densities of scleral fibroblasts (2.5 x 10 squared – 3.75 x 10 cubed/mm cubed) were seeded into three-dimensional collagen matrices, which were formulated to approximate the in vivo scleral matrix, demonstrated a cell density-dependent increase in matrix contraction when no external strain was applied. When these matrices were exposed to an external strain of 8.5% and 11.6%, which was calculated to reflect the in vivo strain under normal and myopic conditions, a rapid increase in contraction was observed within 6 hours, while contraction plateaued after 24 hours. The matrix contraction achieved at 24 hours after application of external strain was significantly higher than that achieved by the matrices maintained under intrinsic strain at that time point.
The role of myofibroblasts in mediating the contraction of the cell-populated matrices observed in experiment one was investigated in the second experiment using immunocytochemical studies. The results of the second experiment demonstrated a cell density-dependent increase in the population of myofibroblasts in matrices maintained under intrinsic strain for 5 days. However, the α-SMA stained cells in matrices exposed to external strains appeared pyknotic at the end of 5 days. Specifically, these cells were smaller in volume and circular with even smaller nuclei. In addition, these cells lacked a-SMA containing stress fibres apparent in the matrices maintained under intrinsic strain. Since a rapid increase in matrix contraction was observed within 6 to 24 hours after the application of strain, the early expression of myofibroblasts (until 24 hours) was investigated. In these matrices there was an increase in α-SMA staining at various early time points (≤ 6 hours), while at 24 hours these cells became pyknotic and lacked stress fibres.…
Subjects/Keywords: myopia; scleral cells
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APA (6th Edition):
SRINIVASALU, N. (2010). Cellular biomechanics of the sclera: role of strain on cell-mediated extracellular matrix contraction and cellular differentiation. (Masters Thesis). University of Melbourne. Retrieved from http://hdl.handle.net/11343/35666
Chicago Manual of Style (16th Edition):
SRINIVASALU, NETHRAJEITH. “Cellular biomechanics of the sclera: role of strain on cell-mediated extracellular matrix contraction and cellular differentiation.” 2010. Masters Thesis, University of Melbourne. Accessed January 25, 2021.
http://hdl.handle.net/11343/35666.
MLA Handbook (7th Edition):
SRINIVASALU, NETHRAJEITH. “Cellular biomechanics of the sclera: role of strain on cell-mediated extracellular matrix contraction and cellular differentiation.” 2010. Web. 25 Jan 2021.
Vancouver:
SRINIVASALU N. Cellular biomechanics of the sclera: role of strain on cell-mediated extracellular matrix contraction and cellular differentiation. [Internet] [Masters thesis]. University of Melbourne; 2010. [cited 2021 Jan 25].
Available from: http://hdl.handle.net/11343/35666.
Council of Science Editors:
SRINIVASALU N. Cellular biomechanics of the sclera: role of strain on cell-mediated extracellular matrix contraction and cellular differentiation. [Masters Thesis]. University of Melbourne; 2010. Available from: http://hdl.handle.net/11343/35666
Duke University
24.
Hawthorne, Felicia Alessandra.
Convergence of Genetic Disease Association and Ocular Expression
.
Degree: 2012, Duke University
URL: http://hdl.handle.net/10161/6133
► The visual system in humans provides the ability to interpret our surroundings from many distances. This complex system serves as a powerful sense which…
(more)
▼ The visual system in humans provides the ability to interpret our surroundings from many distances. This complex system serves as a powerful sense which can drastically impact the quality of life when threatened or eliminated. While the mechanisms involved in visual interpretation are largely understood, many of the mechanisms of ocular diseases remain elusive. The most common ocular disorders are refractive errors, where failure of normal growth processes results in eye components with shape and sizes that are not matched to provide uncorrected sharp visual acuity without correction.
Myopia, or nearsightedness, is a refractive error with prevalence rates of epidemic proportions in some urban Asian settings, and rising in other developed countries. Pathological, or high
myopia, has an increased risk for potentially blinding ocular morbidities which can be irreversible and further negatively impact quality of life.
Myopia, like other common ocular disorders, results from a combination of environmental and genetic factors. Over 20 candidate genomic regions have been identified as involved in myopic development progression. One such locus, MYP3, on chromosome 12q21-23 spans nearly 44 Mb with more than 200 protein-encoding genes mapped within. Sizable candidate disease genomic regions typically require refinement to identify genes or variants within them which may contribute to disease development. Without an understanding of the underlying mechanistic framework of a disease, as is the case with
myopia, biological inferences are difficult to make in prioritizing candidates, which can make finding true disease causing variants seem like finding a needle in a haystack. A better understanding of human ocular growth, as it relates to refractive error, may lead to more knowledgeable approaches to identifying the cause(s) of myopic development and associated ocular diseases. To identify genes involved in ocular growth and development, whole genome expression patterns were assessed in human ocular tissues of fetal versus adult eyes, and adult posterior versus peripheral tissues. No database exists of fetal ocular tissue gene expression. In addition to providing insights into expression patterns during ocular development, these tissues were also compared as a surrogate to study rapid eye growth states such as in
myopia. Only ocular tissue types with clinical phenotypes associated with myopic development were considered. Human retina/retinal pigment epithelium (RPE), choroid, sclera, cornea* and optic nerve* tissues were isolated from fetal (N=9; *N= 6) and adult (N=6) normal donor eyes. The Illumina® whole genome expression microarray platform was used to assess differential expression of genes. Fetal tissues were compared to their adult counterparts while adult posterior tissues were compared to their peripheral counterparts, and the differences in each were assessed using Ingenuity Pathway Analysis (IPA) for enriched functional groups and canonical pathways. Statistical…
Advisors/Committee Members: Young, Terri L (advisor).
Subjects/Keywords: Genetics;
Association;
Expression;
Myopia;
Ocular Disease
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APA (6th Edition):
Hawthorne, F. A. (2012). Convergence of Genetic Disease Association and Ocular Expression
. (Thesis). Duke University. Retrieved from http://hdl.handle.net/10161/6133
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Hawthorne, Felicia Alessandra. “Convergence of Genetic Disease Association and Ocular Expression
.” 2012. Thesis, Duke University. Accessed January 25, 2021.
http://hdl.handle.net/10161/6133.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Hawthorne, Felicia Alessandra. “Convergence of Genetic Disease Association and Ocular Expression
.” 2012. Web. 25 Jan 2021.
Vancouver:
Hawthorne FA. Convergence of Genetic Disease Association and Ocular Expression
. [Internet] [Thesis]. Duke University; 2012. [cited 2021 Jan 25].
Available from: http://hdl.handle.net/10161/6133.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Hawthorne FA. Convergence of Genetic Disease Association and Ocular Expression
. [Thesis]. Duke University; 2012. Available from: http://hdl.handle.net/10161/6133
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
The Ohio State University
25.
Pickrell, Lydia Mary.
The Effect of Dark Adaptation on Red and Blue Light-Driven
Pupil Responses.
Degree: MS, Vision Science, 2020, The Ohio State University
URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1586380901812279
► Purpose: Time spent outdoors has been consistently associated with delaying the onset of myopia. This association may be due to the involvement of intrinsically photosensitive…
(more)
▼ Purpose: Time spent outdoors has been consistently
associated with delaying the onset of
myopia. This association may
be due to the involvement of intrinsically photosensitive retinal
ganglion cells (ipRGCs), considering their role in long-term
ambient illumination detection and connection with dopaminergic
amacrine cells. Pupil responses driven by ipRGC input have
typically been measured clinically in response to flashes of red
and blue light following dark adaptation. However, this is not a
feasible method for testing children, as dark adaptation adds a
significant amount of time to each trial. The purpose of this study
was to evaluate the effect of dark adaptation on the pupil
responses to red and blue light stimulation. Methods: Subjects were
20 adults age 24.0 ± 2.37 years (average ± SD), 55% female, with an
average spherical equivalent (SEQ) refractive error of -3.22 ± 2.78
diopters (Grand Seiko WR-5100K cycloplegic autorefraction), ranging
from -10.61 to +0.77 diopters. The RAPDx pupilometer measured pupil
sizes in response to blue and/or red light oscillating at a low
temporal frequency of 0.1Hz. The standard testing protocol included
5 minutes of dark adaptation prior to each of three stimulus
conditions: alternating red and blue, red-only, then blue-only.
Subjects repeated this standard protocol without dark adaptation.
This study also evaluated whether pupil responses might be enhanced
by two minutes of red-only stimulation (instead of the standard one
minute), once with and once without dark adaptation. These 4 test
conditions were conducted in random order on separate days. The
primary outcome measure was the difference in normalized pupil size
in response to blue-only light compared to blue during the
alternating condition. Results: Consistent with previous research,
pupils tended to become more constricted with repeated exposure to
blue light. The average difference (±SD) in normalized pupil size
between blue-only and alternating blue conditions with dark
adaptation was 10 ± 2.4%. Without dark adaptation, the pupil did
not become as constricted with repeated exposure to blue light,
with the difference reduced by 2.8% (repeated measures ANOVA;
p<0.0001). Compared to the standard protocol, the longer
exposure to red light had no significant effect on the pupil
responses to repeated pulses of blue light (0.8% difference, p =
0.18).Conclusion: Dark adaptation resulted in a significant
reduction in pupil size in response to repeated pulses of blue
light compared to the identical protocols without dark adaptation.
Increasing the exposure to red light had no effect on pupil size in
response to repeated pulses of blue light. Use of dark adaptation
needs to be taken into account during pupillary testing. This
effect could be attributed to an increase in the amount of time
between light exposures allowing dopamine to diffuse throughout the
retina and decrease the threshold levels of the retinal cells
driving the pupil response.
Advisors/Committee Members: Mutti, Donald (Advisor).
Subjects/Keywords: Optics; pupil responses; myopia; ipRGCs; dark adaptation
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Manager
APA (6th Edition):
Pickrell, L. M. (2020). The Effect of Dark Adaptation on Red and Blue Light-Driven
Pupil Responses. (Masters Thesis). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1586380901812279
Chicago Manual of Style (16th Edition):
Pickrell, Lydia Mary. “The Effect of Dark Adaptation on Red and Blue Light-Driven
Pupil Responses.” 2020. Masters Thesis, The Ohio State University. Accessed January 25, 2021.
http://rave.ohiolink.edu/etdc/view?acc_num=osu1586380901812279.
MLA Handbook (7th Edition):
Pickrell, Lydia Mary. “The Effect of Dark Adaptation on Red and Blue Light-Driven
Pupil Responses.” 2020. Web. 25 Jan 2021.
Vancouver:
Pickrell LM. The Effect of Dark Adaptation on Red and Blue Light-Driven
Pupil Responses. [Internet] [Masters thesis]. The Ohio State University; 2020. [cited 2021 Jan 25].
Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1586380901812279.
Council of Science Editors:
Pickrell LM. The Effect of Dark Adaptation on Red and Blue Light-Driven
Pupil Responses. [Masters Thesis]. The Ohio State University; 2020. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1586380901812279
Queensland University of Technology
26.
Ting, Wai Ki.
Instrument myopia and myopia progression in Hong Kong microscopists.
Degree: 2004, Queensland University of Technology
URL: https://eprints.qut.edu.au/15958/
► People who work in occupations that involve intensive near work are thought to have a higher chance of developing myopia than other people. For example,…
(more)
▼ People who work in occupations that involve intensive near work are thought to have a higher chance of developing myopia than other people. For example, microscopists in the United Kingdom have a higher prevalence of myopia than that of the general community. The prevalence of myopia in Hong Kong is extremely high (71 %) and Hong Kong Chinese people are particularly susceptible to myopia development and progression due to environmental factors. It is possible that this environmental susceptibility may lead to Hong Kong Chinese microscopists developing even
greater levels of myopia. We found that the prevalence of myopia in Hong Kong microscopists (n=47, mean age=31 years) was higher than that of United Kingdom microscopists (87 % c.f. 71 %) and similar aged people within the general Hong
Kong population (87 % c.f. 71 %; −4.45 D c.f. -3.00 D). However, while in most microscopists (83 % of 36 microscopists followed for a two-year period) the amount of myopia and vitreous chamber depth increased over a two year monitoring period (−0.11 D, 0.06 mm), the increase was not clinically significant. We hypothesised that the slower myopia progression rate in Hong Kong microscopists may be the result of their older average age (Hong Kong microscopists: 31.7 years c.f. United Kingdom
microscopists: 29.7 years).
When a person looks into a microscope, excessive accommodation occurs even though the microscope is designed to render the magnified image at optical infinity (zero accommodation and vergence demand). This over accommodation is called instrument myopia. It is possible that this over accommodation is linked to the myopia development and progression that occurs in users of these instruments. We found that instrument myopia remained consistent with different viewing conditions and microscope settings (inexperienced microscopists, n=20, mean age: 24.1 years, mean spherical refractive error: −2.83 D). The magnitude of instrument myopia was
not correlated with either the age or refractive error of the microscope user, while it was lower in those users with greater experience (inexperienced microscopists: 1.03
D c.f. experienced microscopists: 0.43 D). As the Hong Kong microscopists (n=10, mean age: 31.2 years, mean spherical refractive error: −3.39 D) who partook in this study were experienced (6.3 years spent working in this field), this may have contributed to the lower myopia progression that was observed.
Studies to determine the main contribution to the phenomena of instrument myopia were also conducted. Instrument myopia was not correlated with convergence when looking into microscope (r= −0.224, p=0.342), near phoria (r=0.351, p=0.129), AC/A ratio (r= −0.135, p=0.571), the convergence induced by the excessive accommodative response (r= −0.028, p=0.906), lag of accommodation (r=0.065, p=0.785) and tonic accommodation (r=0.142, p=0.551). We suggest that the main contribution to instrument myopia during microscopy is proximal accommodation
due to the awareness of the closeness, caused by the height of the…
Subjects/Keywords: myopia; nearwork; early adult-onset myopia; occupational myopia; prevalence of myopia; myopia development; myopia progression; microscopy; instrument myopia; tonic accomodation; proximal accomodation
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Manager
APA (6th Edition):
Ting, W. K. (2004). Instrument myopia and myopia progression in Hong Kong microscopists. (Thesis). Queensland University of Technology. Retrieved from https://eprints.qut.edu.au/15958/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Ting, Wai Ki. “Instrument myopia and myopia progression in Hong Kong microscopists.” 2004. Thesis, Queensland University of Technology. Accessed January 25, 2021.
https://eprints.qut.edu.au/15958/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Ting, Wai Ki. “Instrument myopia and myopia progression in Hong Kong microscopists.” 2004. Web. 25 Jan 2021.
Vancouver:
Ting WK. Instrument myopia and myopia progression in Hong Kong microscopists. [Internet] [Thesis]. Queensland University of Technology; 2004. [cited 2021 Jan 25].
Available from: https://eprints.qut.edu.au/15958/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Ting WK. Instrument myopia and myopia progression in Hong Kong microscopists. [Thesis]. Queensland University of Technology; 2004. Available from: https://eprints.qut.edu.au/15958/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Hong Kong
27.
Xu, Shule.
Assessing the evidence for
interventions that slow the progression of myopia: a literature
review.
Degree: 2010, University of Hong Kong
URL: http://hdl.handle.net/10722/132332
Subjects/Keywords: Myopia
- Treatment - China - Hong Kong.; Myopia
- Treatment.
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Manager
APA (6th Edition):
Xu, S. (2010). Assessing the evidence for
interventions that slow the progression of myopia: a literature
review. (Thesis). University of Hong Kong. Retrieved from http://hdl.handle.net/10722/132332
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Xu, Shule. “Assessing the evidence for
interventions that slow the progression of myopia: a literature
review.” 2010. Thesis, University of Hong Kong. Accessed January 25, 2021.
http://hdl.handle.net/10722/132332.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Xu, Shule. “Assessing the evidence for
interventions that slow the progression of myopia: a literature
review.” 2010. Web. 25 Jan 2021.
Vancouver:
Xu S. Assessing the evidence for
interventions that slow the progression of myopia: a literature
review. [Internet] [Thesis]. University of Hong Kong; 2010. [cited 2021 Jan 25].
Available from: http://hdl.handle.net/10722/132332.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Xu S. Assessing the evidence for
interventions that slow the progression of myopia: a literature
review. [Thesis]. University of Hong Kong; 2010. Available from: http://hdl.handle.net/10722/132332
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Debrecen
28.
Palomares, Aaron.
Myopia, myopia progression and treatment
.
Degree: DE – Általános Orvostudományi Kar, University of Debrecen
URL: http://hdl.handle.net/2437/242850
► Myopia is one of the most common eye conditions that has developed in the world, affecting a large percentage of the population. The prevalence has…
(more)
▼ Myopia is one of the most common eye conditions that has developed in the world, affecting a large percentage of the population. The prevalence has dramatically increased in the last few decades, influencing people from different ethnicities, age, gender, occupational status etc. For many years, scientist have been studying the cause and the process of
myopia, in order to be able to prevent it and possibly cure it.
Advisors/Committee Members: Kettesy, Andrea Beáta (advisor), Debreceni Egyetem::Általános Orvostudományi Kar::Szemklinika (advisor).
Subjects/Keywords: myopia progression;
Myopia treatment options;
orthokeratology;
atropine 0.01%
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APA (6th Edition):
Palomares, A. (n.d.). Myopia, myopia progression and treatment
. (Thesis). University of Debrecen. Retrieved from http://hdl.handle.net/2437/242850
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Palomares, Aaron. “Myopia, myopia progression and treatment
.” Thesis, University of Debrecen. Accessed January 25, 2021.
http://hdl.handle.net/2437/242850.
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Palomares, Aaron. “Myopia, myopia progression and treatment
.” Web. 25 Jan 2021.
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Vancouver:
Palomares A. Myopia, myopia progression and treatment
. [Internet] [Thesis]. University of Debrecen; [cited 2021 Jan 25].
Available from: http://hdl.handle.net/2437/242850.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.
Council of Science Editors:
Palomares A. Myopia, myopia progression and treatment
. [Thesis]. University of Debrecen; Available from: http://hdl.handle.net/2437/242850
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.
University of New South Wales
29.
Martinez, Aldo A.
On and off-axis monochromatic aberrations and myopia in young children.
Degree: Optometry & Vision Science, 2007, University of New South Wales
URL: http://handle.unsw.edu.au/1959.4/33676
;
https://unsworks.unsw.edu.au/fapi/datastream/unsworks:1787/SOURCE2?view=true
► Purpose: To study on and off-axis wavefront aberration of eyes of children and to determine the relationship with refractive error development.Methods: On and off-axis ocular…
(more)
▼ Purpose: To study on and off-axis wavefront aberration of eyes of children and to determine the relationship with refractive error development.Methods: On and off-axis ocular aberrations of cyclopleged eyes of children (mostly 12 year olds) were measured and compared to data obtained from a group of mostly 6 year old children. Only data from the right eyes were analysed (pupil diameter=5 mm) and categorised into refractive error groups based on M. Differences in on and off-axis aberrations between refractive and ethnic groups were analysed using univariate and multivariate analyses of variance with adjustment for multiple comparisons. Off-axis refraction was analysed using skiagrams and mean relative spherical equivalent.Results: Data from 1,636 12 year old children (mean age 12.6 ± 0.4 years) was analysed. Lower order aberrations were the largest and higher order aberrations contributed to only 25% of the wavefront. There were no differences in the amount of total higher orders between refractive groups. Of the individual higher orders, spherical aberration was greater in hyperopic eyes (0.07 ± 0.06 µm) in comparison to emmetropic and myopic eyes (0.05 ± 0.04 µm and 0.05 ± 0.04 µm) (p<0.001). Myopic eyes had more positive values of Z(3,-1) (p<0.05). Similar results were obtained for the 1,364 6 year old children (mean age 6.7 0.4 years). Despite East Asian children being more myopic than other ethnic groups (p<0.01), there were no differences in higher orders except for low hyperopic East Asian eyes presenting with higher levels of positive spherical aberrations (p<0.001). When compared to the fovea, off-axis myopic eyes had hyperopia (0.55 to 1.66 D) and emmetropes and hyperopes had
myopia (0.10 to -2.00 D). Astigmatism and defocus were the dominant off-axis aberrations. The magnitude of higher order aberrations (mostly 3rd orders) increased with eccentricity but was similar across refractive error groups.Conclusions: Myopic eyes do not have abnormal or excessive levels of on and off-axis higher order aberrations but had patterns of off-axis refraction that may be associated with progression. Considerable inter-
subject variability in higher order aberrations was seen for all refractive groups. However, their magnitude was small and suggests that any impact on the optical quality of the eye is negligible.
Advisors/Committee Members: Sankaridurg, Padmaja, Institute for Eye Research.
Subjects/Keywords: Peripheral Refraction; Myopia; Monochromatic Aberrations; Children; Sydney Myopia Study
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APA (6th Edition):
Martinez, A. A. (2007). On and off-axis monochromatic aberrations and myopia in young children. (Doctoral Dissertation). University of New South Wales. Retrieved from http://handle.unsw.edu.au/1959.4/33676 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:1787/SOURCE2?view=true
Chicago Manual of Style (16th Edition):
Martinez, Aldo A. “On and off-axis monochromatic aberrations and myopia in young children.” 2007. Doctoral Dissertation, University of New South Wales. Accessed January 25, 2021.
http://handle.unsw.edu.au/1959.4/33676 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:1787/SOURCE2?view=true.
MLA Handbook (7th Edition):
Martinez, Aldo A. “On and off-axis monochromatic aberrations and myopia in young children.” 2007. Web. 25 Jan 2021.
Vancouver:
Martinez AA. On and off-axis monochromatic aberrations and myopia in young children. [Internet] [Doctoral dissertation]. University of New South Wales; 2007. [cited 2021 Jan 25].
Available from: http://handle.unsw.edu.au/1959.4/33676 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:1787/SOURCE2?view=true.
Council of Science Editors:
Martinez AA. On and off-axis monochromatic aberrations and myopia in young children. [Doctoral Dissertation]. University of New South Wales; 2007. Available from: http://handle.unsw.edu.au/1959.4/33676 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:1787/SOURCE2?view=true
Universiteit Utrecht
30.
Ee, F.M. van.
Ik zie, ik zie wat jij niet ziet:
Bias in de aandacht ten opzichte van seksuele cues in impulsieve of reflectieve staat.
Degree: 2010, Universiteit Utrecht
URL: http://dspace.library.uu.nl:8080/handle/1874/45164
► Volgens de “attentional myopia theory” (Mann & Ward, 2004) zijn er omstandigheden waardoor de aandacht beperkt wordt en men zich uitsluitend laten leiden door de…
(more)
▼ Volgens de “attentional
myopia theory” (Mann & Ward, 2004) zijn er omstandigheden waardoor de aandacht beperkt wordt en men zich uitsluitend laten leiden door de meest saillante cue. Hetzelfde effect kan aanwezig zijn voor mensen die in een impulsieve staat verkeren. Er is onderzocht of cognitieve staat invloed heeft op de aandachts bias ten opzichte van seksuele woorden. Door middel van het dot probe paradigma is getest of mensen in een impulsieve staat de aandacht alleen op de meest saillante cue richten en mensen in een reflectieve staat de aandacht op zowel de meest saillante seksuele cue als op andere relevante cues richten. Het effect van cognitieve staat op aandachts bias wordt door de resultaten niet ondersteund. Mensen in een impulsieve staat verschillen in aandachts bias niet van mensen in een reflectieve staat. Wel hebben mensen moeite met het losmaken van de aandacht van een seksuele cue.
Advisors/Committee Members: Daas, C. den.
Subjects/Keywords: Sociale Wetenschappen; Aandachts bias; Seksuele cues; Attentional Myopia Theory; Cognitieve staat
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APA (6th Edition):
Ee, F. M. v. (2010). Ik zie, ik zie wat jij niet ziet:
Bias in de aandacht ten opzichte van seksuele cues in impulsieve of reflectieve staat. (Masters Thesis). Universiteit Utrecht. Retrieved from http://dspace.library.uu.nl:8080/handle/1874/45164
Chicago Manual of Style (16th Edition):
Ee, F M van. “Ik zie, ik zie wat jij niet ziet:
Bias in de aandacht ten opzichte van seksuele cues in impulsieve of reflectieve staat.” 2010. Masters Thesis, Universiteit Utrecht. Accessed January 25, 2021.
http://dspace.library.uu.nl:8080/handle/1874/45164.
MLA Handbook (7th Edition):
Ee, F M van. “Ik zie, ik zie wat jij niet ziet:
Bias in de aandacht ten opzichte van seksuele cues in impulsieve of reflectieve staat.” 2010. Web. 25 Jan 2021.
Vancouver:
Ee FMv. Ik zie, ik zie wat jij niet ziet:
Bias in de aandacht ten opzichte van seksuele cues in impulsieve of reflectieve staat. [Internet] [Masters thesis]. Universiteit Utrecht; 2010. [cited 2021 Jan 25].
Available from: http://dspace.library.uu.nl:8080/handle/1874/45164.
Council of Science Editors:
Ee FMv. Ik zie, ik zie wat jij niet ziet:
Bias in de aandacht ten opzichte van seksuele cues in impulsieve of reflectieve staat. [Masters Thesis]. Universiteit Utrecht; 2010. Available from: http://dspace.library.uu.nl:8080/handle/1874/45164
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