subject:(Multi modality)

Universiteit Utrecht

1. Soesbergen, F. Teaching with CLIL - Language and Learning Come Together.

Degree: 2007, Universiteit Utrecht

URL: http://dspace.library.uu.nl:8080/handle/1874/210444

► The educational concept of Content and Language Integrated Learning is an invaluable tool in promoting learner understanding of a secondary language. It is one of… (more)

Subjects/Keywords: CLIL. content; langauge; learning; multi-modality; cooperative

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APA (6^th Edition):

Soesbergen, F. (2007). Teaching with CLIL - Language and Learning Come Together. (Masters Thesis). Universiteit Utrecht. Retrieved from http://dspace.library.uu.nl:8080/handle/1874/210444

Chicago Manual of Style (16^th Edition):

Soesbergen, F. “Teaching with CLIL - Language and Learning Come Together.” 2007. Masters Thesis, Universiteit Utrecht. Accessed December 07, 2019. http://dspace.library.uu.nl:8080/handle/1874/210444.

MLA Handbook (7^th Edition):

Soesbergen, F. “Teaching with CLIL - Language and Learning Come Together.” 2007. Web. 07 Dec 2019.

Vancouver:

Soesbergen F. Teaching with CLIL - Language and Learning Come Together. [Internet] [Masters thesis]. Universiteit Utrecht; 2007. [cited 2019 Dec 07]. Available from: http://dspace.library.uu.nl:8080/handle/1874/210444.

Council of Science Editors:

Soesbergen F. Teaching with CLIL - Language and Learning Come Together. [Masters Thesis]. Universiteit Utrecht; 2007. Available from: http://dspace.library.uu.nl:8080/handle/1874/210444

Universiteit Utrecht

2. Soesbergen, F. Teaching with CLIL: Learning and Language Come Together.

Degree: 2011, Universiteit Utrecht

URL: http://dspace.library.uu.nl:8080/handle/1874/211058

► The educational concept of Content and Language Integrated Learning is an invaluable tool in promoting learner understanding of a secondary language. It is one of… (more)

Subjects/Keywords: IVLOS; Content, Language, Multi-modality, cooperative, learning, multiple intelligence, CLIL

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APA (6^th Edition):

Soesbergen, F. (2011). Teaching with CLIL: Learning and Language Come Together. (Masters Thesis). Universiteit Utrecht. Retrieved from http://dspace.library.uu.nl:8080/handle/1874/211058

Chicago Manual of Style (16^th Edition):

Soesbergen, F. “Teaching with CLIL: Learning and Language Come Together.” 2011. Masters Thesis, Universiteit Utrecht. Accessed December 07, 2019. http://dspace.library.uu.nl:8080/handle/1874/211058.

MLA Handbook (7^th Edition):

Soesbergen, F. “Teaching with CLIL: Learning and Language Come Together.” 2011. Web. 07 Dec 2019.

Vancouver:

Soesbergen F. Teaching with CLIL: Learning and Language Come Together. [Internet] [Masters thesis]. Universiteit Utrecht; 2011. [cited 2019 Dec 07]. Available from: http://dspace.library.uu.nl:8080/handle/1874/211058.

Council of Science Editors:

Soesbergen F. Teaching with CLIL: Learning and Language Come Together. [Masters Thesis]. Universiteit Utrecht; 2011. Available from: http://dspace.library.uu.nl:8080/handle/1874/211058

Georgia Tech

3. Pang, Bo. Development of gold nanoparticle-based theranostic agents for molecular imaging and cancer therapy.

Degree: PhD, Biomedical Engineering (Joint GT/Emory Department), 2017, Georgia Tech

URL: http://hdl.handle.net/1853/59767

► This research explored the use of Au nanoparticles on molecular imaging and cancer theranostics, with focuses on the fabrication of new materials, the incorporation of… (more)

Subjects/Keywords: Gold nanoparticle; Controlled synthesis; Multi-modality imaging; Nuclear imaging; Cancer theranostics

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APA (6^th Edition):

Pang, B. (2017). Development of gold nanoparticle-based theranostic agents for molecular imaging and cancer therapy. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/59767

Chicago Manual of Style (16^th Edition):

Pang, Bo. “Development of gold nanoparticle-based theranostic agents for molecular imaging and cancer therapy.” 2017. Doctoral Dissertation, Georgia Tech. Accessed December 07, 2019. http://hdl.handle.net/1853/59767.

MLA Handbook (7^th Edition):

Pang, Bo. “Development of gold nanoparticle-based theranostic agents for molecular imaging and cancer therapy.” 2017. Web. 07 Dec 2019.

Vancouver:

Pang B. Development of gold nanoparticle-based theranostic agents for molecular imaging and cancer therapy. [Internet] [Doctoral dissertation]. Georgia Tech; 2017. [cited 2019 Dec 07]. Available from: http://hdl.handle.net/1853/59767.

Council of Science Editors:

Pang B. Development of gold nanoparticle-based theranostic agents for molecular imaging and cancer therapy. [Doctoral Dissertation]. Georgia Tech; 2017. Available from: http://hdl.handle.net/1853/59767

University of Toronto

4. Moosvi, Firas. Physical Co-registration of Magnetic Resonance Imaging and Ultrasound in vivo.

Degree: 2012, University of Toronto

URL: http://hdl.handle.net/1807/33669

►

The use of complementary non-invasive imaging modalities has been proposed to track disease progression, particularly cancer, while simultaneously evaluating therapeutic efficacy. A major obstacle is… (more)

Subjects/Keywords: multi modality imaging; MRI; US; imaging; co-registration; mouse tumours; 0760

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APA (6^th Edition):

Moosvi, F. (2012). Physical Co-registration of Magnetic Resonance Imaging and Ultrasound in vivo. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/33669

Chicago Manual of Style (16^th Edition):

Moosvi, Firas. “Physical Co-registration of Magnetic Resonance Imaging and Ultrasound in vivo.” 2012. Masters Thesis, University of Toronto. Accessed December 07, 2019. http://hdl.handle.net/1807/33669.

MLA Handbook (7^th Edition):

Moosvi, Firas. “Physical Co-registration of Magnetic Resonance Imaging and Ultrasound in vivo.” 2012. Web. 07 Dec 2019.

Vancouver:

Moosvi F. Physical Co-registration of Magnetic Resonance Imaging and Ultrasound in vivo. [Internet] [Masters thesis]. University of Toronto; 2012. [cited 2019 Dec 07]. Available from: http://hdl.handle.net/1807/33669.

Council of Science Editors:

Moosvi F. Physical Co-registration of Magnetic Resonance Imaging and Ultrasound in vivo. [Masters Thesis]. University of Toronto; 2012. Available from: http://hdl.handle.net/1807/33669

University of Oxford

5. Prince, John. Objective assessment of Parkinson's disease using machine learning.

Degree: PhD, 2018, University of Oxford

URL: http://ora.ox.ac.uk/objects/uuid:fa35ec54-cb90-42f9-ae1a-cf1cf73f32e3 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.772535

► Neurodegenerative disorders, such as Parkinson's disease (PD), are infamously heterogeneous in regards to onset age, symptom prevalence, and severity progression rate. The current 'gold standard'… (more)

▼ Neurodegenerative disorders, such as Parkinson's disease (PD), are infamously heterogeneous in regards to onset age, symptom prevalence, and severity progression rate. The current 'gold standard' techniques currently in use to assess the highly debilitating motor and non-motor symptoms are subjective, infrequent, and often ineffective with up to 20% of cases going undiagnosed until post-mortem. As such, these traditional and well established clinical assessment techniques are now starting to be fused with data-driven approaches in a bid to improve diagnosis and severity monitoring through the identification of objective disease biomarkers. Digital sensors present the opportunity to extract quantitative measures that are representative of disease presence and severity. However, existing studies using digital sensors to perform disease quantification are restricted by small cohorts, inconsistent experimental protocols, and purely cross-sectional analyses. The objective of this thesis is to provide novel insights as to how digital sensors can be further leveraged alongside prior clinical knowledge in order to improve the way Parkinson's disease is assessed in both clinical and remote environments. This thesis focuses on two large datasets that are juxtaposed in data quality, collection environment, and data type. Firstly, a clinical based approach to disease quantification is performed wherein an extensive network of wearable sensors is introduced into routine clinical care. Using this clinical dataset, the ability of wearable sensors to detect digital biomarkers distinctive of PD is investigated including the use of these biomarkers to perform automatic disease classification and severity prediction. Due to the longitudinal nature of data collection, new insights are revealed pertaining to symptom progression and the benefit of including longitudinal symptom variation into classification tasks. Secondly, the efficacy of performing disease assessment entirely in a remote environment using smartphones is investigated. Data was collected relating to many areas of disease manifestation and was often contributed daily by participants on a longitudinal basis. However, the remotely collected data suffers from a large degree of missingness, poor participant retention rate, and variable environmental conditions presenting new challenges during its analysis. High-frequency longitudinal analyses are performed and identify previously unseen motor and non-motor symptom progression characteristics. In order to perform disease classification using this dataset, a novel methodology is presented that compensates for the large quantities of source-wise missing data which, when combined with a stateof- the-art convolutional neural network, subsequently improves classification accuracy from 73.1% to 82.0%. Finally, a consistent analysis protocol is implemented on both datasets whilst simulating source-wise missing data; enabling a comprehensive comparison of missing data strategies for the purpose of disease classification. This thesis…

Subjects/Keywords: Neuroscience; Multi-Modality Data Fusion; Deep Learning; Machine Learning

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APA (6^th Edition):

Prince, J. (2018). Objective assessment of Parkinson's disease using machine learning. (Doctoral Dissertation). University of Oxford. Retrieved from http://ora.ox.ac.uk/objects/uuid:fa35ec54-cb90-42f9-ae1a-cf1cf73f32e3 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.772535

Chicago Manual of Style (16^th Edition):

Prince, John. “Objective assessment of Parkinson's disease using machine learning.” 2018. Doctoral Dissertation, University of Oxford. Accessed December 07, 2019. http://ora.ox.ac.uk/objects/uuid:fa35ec54-cb90-42f9-ae1a-cf1cf73f32e3 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.772535.

MLA Handbook (7^th Edition):

Prince, John. “Objective assessment of Parkinson's disease using machine learning.” 2018. Web. 07 Dec 2019.

Vancouver:

Prince J. Objective assessment of Parkinson's disease using machine learning. [Internet] [Doctoral dissertation]. University of Oxford; 2018. [cited 2019 Dec 07]. Available from: http://ora.ox.ac.uk/objects/uuid:fa35ec54-cb90-42f9-ae1a-cf1cf73f32e3 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.772535.

Council of Science Editors:

Prince J. Objective assessment of Parkinson's disease using machine learning. [Doctoral Dissertation]. University of Oxford; 2018. Available from: http://ora.ox.ac.uk/objects/uuid:fa35ec54-cb90-42f9-ae1a-cf1cf73f32e3 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.772535

Arizona State University

6. Sahu, Sulagna. Intra- and Inter-Modality Registration for Validation of MRI based Hypoxia Imaging.

Degree: Biomedical Engineering, 2018, Arizona State University

URL: http://repository.asu.edu/items/50603

► Hypoxia is a pathophysiological condition which results from lack of oxygen supply in tumors. The assessment of tumor hypoxia and its response to therapies can… (more)

▼ Hypoxia is a pathophysiological condition which results from lack of oxygen supply in tumors. The assessment of tumor hypoxia and its response to therapies can provide guidelines for optimization and personalization of therapeutic protocols for better treatment. Previous research has shown the difficulty in measuring hypoxia anatomically due to its heterogenous nature. This makes the study of hypoxia through various imaging modalities and mapping techniques crucial. The potential of hypoxia targeting T1 contrast agent GdDO3NI in generating hypoxia maps has been studied earlier. In this work, the similarities between hypoxia maps generated by MRI using GdDO3NI and pimonidazole based immunohistochemistry (IHC) in non-small cell lung carcinoma bearing mice have been studied. Six NCI-H1975 tumor-bearing mice were studied. All animal studies were approved by Arizona State University’s Institute of Animal Care and Use Committee (IACUC). Post co-injection of GdDO3NI and pimonidazole, T1 weighted 3D gradient echo MR images were acquired. For ex-vivo analysis of hypoxia, 30 μm thick tumor sections were obtained for each harvested tumor and were stained for pimonidazole and counter-stained with DAPI for nuclear staining. Pimonidazole (PIMO) is clinically used as a “gold standard” hypoxia marker. The key process involved stacking and iterative registration based on quality metric SSIM (Structural Similarity) Index of DAPI stained images of 5 consecutive tumor sections to produce a 3D volume stack of 150 μm thickness. Information from the 3D volume is combined to produce one final slide by averaging. The same registration transform was applied to stack the pimonidazole images which were previously thresholded to highlight hypoxic regions. The registered IHC stack was then co-registered with a single thresholded T1 weighted gradient echo MRI slice of the same location (~156 μm thick) using an elastic B-splines transform. The same transform was applied to achieve the co-registration of pimonidazole and MR percentage enhancement image. Image similarity index after the co-registration was found to be greater than 0.5 for 5 of the animals suggesting good correlation. R2 values were calculated for both hypoxic regions as well as tumor boundaries. All the tumors showed a high boundary correlation value of R2 greater than 0.8. Half of the animals showed high R2 values greater than 0.5 for hypoxic fractions. The RMSE values for the co-registration of all the animals were found to be low further suggesting better correspondence and validating the MR based hypoxia imaging.

Subjects/Keywords: Biomedical engineering; Engineering; Oncology; GdDO3NI; Multi-modality Registration; Pimonidazole; Tumor hypoxia

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APA (6^th Edition):

Sahu, S. (2018). Intra- and Inter-Modality Registration for Validation of MRI based Hypoxia Imaging. (Masters Thesis). Arizona State University. Retrieved from http://repository.asu.edu/items/50603

Chicago Manual of Style (16^th Edition):

Sahu, Sulagna. “Intra- and Inter-Modality Registration for Validation of MRI based Hypoxia Imaging.” 2018. Masters Thesis, Arizona State University. Accessed December 07, 2019. http://repository.asu.edu/items/50603.

MLA Handbook (7^th Edition):

Sahu, Sulagna. “Intra- and Inter-Modality Registration for Validation of MRI based Hypoxia Imaging.” 2018. Web. 07 Dec 2019.

Vancouver:

Sahu S. Intra- and Inter-Modality Registration for Validation of MRI based Hypoxia Imaging. [Internet] [Masters thesis]. Arizona State University; 2018. [cited 2019 Dec 07]. Available from: http://repository.asu.edu/items/50603.

Council of Science Editors:

Sahu S. Intra- and Inter-Modality Registration for Validation of MRI based Hypoxia Imaging. [Masters Thesis]. Arizona State University; 2018. Available from: http://repository.asu.edu/items/50603

University of Minnesota

7. Karpatne, Anuj. Predictive Learning with Heterogeneity in Populations.

Degree: PhD, Computer Science, 2017, University of Minnesota

URL: http://hdl.handle.net/11299/192667

► Predictive learning forms the backbone of several data-driven systems powering scientific as well as commercial applications, e.g., filtering spam messages, detecting faces in images, forecasting… (more)

▼ Predictive learning forms the backbone of several data-driven systems powering scientific as well as commercial applications, e.g., filtering spam messages, detecting faces in images, forecasting health risks, and mapping ecological resources. However, one of the major challenges in applying standard predictive learning methods in real-world applications is the heterogeneity in populations of data instances, i.e., different groups (or populations) of data instances show different nature of predictive relationships. For example, different populations of human subjects may show different risks for a disease even if they have similar diagnosis reports, depending on their ethnic profiles, medical history, and lifestyle choices. In the presence of population heterogeneity, a central challenge is that the training data comprises of instances belonging from multiple populations, and the instances in the test set may be from a different population than that of the training instances. This limits the effectiveness of standard predictive learning frameworks that are based on the assumption that the instances are independent and identically distributed (i.i.d), which are ideally true only in simplistic settings. This thesis introduces several ways of learning predictive models with heterogeneity in populations, by incorporating information about the context of every data instance, which is available in varying types and formats in different application settings. It introduces a novel multi-task learning framework for problems where we have access to some ancillary variables that can be grouped to produce homogeneous partitions of data instances, thus addressing the heterogeneity in populations. This thesis also introduces a novel strategy for constructing mode-specific ensembles in binary classification settings, where each class shows multi-modal distribution due to the heterogeneity in their populations. When the context of data instances is implicitly defined such that the test data is known to comprise of contextually similar groups, this thesis presents a novel framework for adapting classification decisions using the group-level properties of test instances. This thesis also builds the foundations of a novel paradigm of scientific discovery, termed as theory-guided data science, that seeks to explore the full potential of data science methods but without ignoring the treasure of knowledge contained in scientific theories and principles.

Subjects/Keywords: data mining; ensemble learning; machine learning; multi-modality; multi-task learning; population heterogeneity

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APA (6^th Edition):

Karpatne, A. (2017). Predictive Learning with Heterogeneity in Populations. (Doctoral Dissertation). University of Minnesota. Retrieved from http://hdl.handle.net/11299/192667

Chicago Manual of Style (16^th Edition):

Karpatne, Anuj. “Predictive Learning with Heterogeneity in Populations.” 2017. Doctoral Dissertation, University of Minnesota. Accessed December 07, 2019. http://hdl.handle.net/11299/192667.

MLA Handbook (7^th Edition):

Karpatne, Anuj. “Predictive Learning with Heterogeneity in Populations.” 2017. Web. 07 Dec 2019.

Vancouver:

Karpatne A. Predictive Learning with Heterogeneity in Populations. [Internet] [Doctoral dissertation]. University of Minnesota; 2017. [cited 2019 Dec 07]. Available from: http://hdl.handle.net/11299/192667.

Council of Science Editors:

Karpatne A. Predictive Learning with Heterogeneity in Populations. [Doctoral Dissertation]. University of Minnesota; 2017. Available from: http://hdl.handle.net/11299/192667

University of Southern California

8. Somayajula, Sangeetha. Information theoretic measures for PET image reconstruction and non-rigid image registration.

Degree: PhD, Electrical Engineering, 2009, University of Southern California

URL: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/268947/rec/3488

► We explore the use of information theoretic measures for positron emission tomography (PET) image reconstruction and for multi-modality non-rigid registration.; PET is a functional imaging… (more)

▼ We explore the use of information theoretic measures for positron emission tomography (PET) image reconstruction and for multi-modality non-rigid registration.; PET is a functional imaging modality based on imaging the uptake of a radioactive tracer. PET images are typically of low resolution and are accompanied by high resolution anatomical images such as CT or MR for localization of activity. PET tracer uptake typically results in a spatial density that is highly correlated to the anatomical morphology. The incorporation of this correlated anatomical information can potentially improve the quality of low resolution PET images. We propose using priors based on information theoretic similarity measures to incorporate anatomical information in PET reconstruction. We compare and evaluate the use of mutual information (MI) and joint entropy (JE) between feature vectors extracted from the anatomical and PET images as priors in PET reconstruction. These feature vectors are defined using scale-space theory such that they emphasize prominent boundaries in the anatomical and functional images, and attach less importance to detail and noise that is less likely to be correlated in the two images. We present an efficient method of computing these priors and their derivatives based on fast Fourier transforms that reduce the complexity of their convolution-like expressions. Through simulations and clinical data reconstructions, we evaluate the performance of MI and JE based priors in comparison to a quadratic prior, which does not use any anatomical information. We also apply these priors to the problem of positron range correction. Positron range is the distance traveled by a positron before annihilation, thereby causing a blurring effect in the reconstructed image and limiting its resolution. We use information theoretic priors in conjunction with a system model that incorporates positron range by modeling it as a spatially invariant blurring that is truncated at the boundary of the imaging volume. We present phantom simulation and real data results comparing these priors to the range corrected system model with quadratic prior.; Small animal non-rigid registration is especially challenging because of the presence of rigid structures like the skeleton within non-rigid soft tissue. We present two approaches to multi-modality imaging that can be applied to clinical as well as pre-clinical images. First, we describe a non-parametric scale-space approach to MI based non-rigid small animal image registration. In this application, the goal is to simultaneously align global structure as well as detail in the images. We present results based on CT images obtained from two time points of a longitudinal mouse study that demonstrate that this approach aligns both skeleton and soft tissue better than a commonly used hierarchical approach. Second, we explore an alternative formulation that uses the log likelihood of the reference image (target) given the image to be registered (template) as a similarity metric wherein the likelihood is… Advisors/Committee Members: Leahy, Richard M. (Committee Chair), Nayak, Krishna S. (Committee Member), Singh, Manbir (Committee Member).

Subjects/Keywords: biomedical imaging; joint entropy; multi-modality imaging; mutual information; PET reconstruction; image registration

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APA (6^th Edition):

Somayajula, S. (2009). Information theoretic measures for PET image reconstruction and non-rigid image registration. (Doctoral Dissertation). University of Southern California. Retrieved from http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/268947/rec/3488

Chicago Manual of Style (16^th Edition):

Somayajula, Sangeetha. “Information theoretic measures for PET image reconstruction and non-rigid image registration.” 2009. Doctoral Dissertation, University of Southern California. Accessed December 07, 2019. http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/268947/rec/3488.

MLA Handbook (7^th Edition):

Somayajula, Sangeetha. “Information theoretic measures for PET image reconstruction and non-rigid image registration.” 2009. Web. 07 Dec 2019.

Vancouver:

Somayajula S. Information theoretic measures for PET image reconstruction and non-rigid image registration. [Internet] [Doctoral dissertation]. University of Southern California; 2009. [cited 2019 Dec 07]. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/268947/rec/3488.

Council of Science Editors:

Somayajula S. Information theoretic measures for PET image reconstruction and non-rigid image registration. [Doctoral Dissertation]. University of Southern California; 2009. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/268947/rec/3488

University of Southern California

9. Ma, Teng. Multi-modality intravascular imaging by combined use of ultrasonic and opticial techniques.

Degree: PhD, Biomedical Engineering, 2017, University of Southern California

URL: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/616089/rec/4247

► Thin-capped fibroatheroma (TCFA) is considered to be the phenotype of vulnerable atherosclerotic plaque based on the pathological studies, whose sudden rupture is frequently responsible for… (more)

▼ Thin-capped fibroatheroma (TCFA) is considered to be the phenotype of vulnerable atherosclerotic plaque based on the pathological studies, whose sudden rupture is frequently responsible for acute coronary syndrome (ACS). Early detection and prognosis of TCFA will not only guide the therapeutic strategy to benefit the patients, but also contribute to the study of natural history of vulnerable plaque that is still elusive. To date, various imaging modalities employing ultrasonic scattering contrast with radio frequency analysis, optical scattering contrast, optical absorption mechanism, spectroscopic analysis and targeted-molecular imaging method, provide diverse visualizations of coronary arteries both in clinic and research. However, none of these imaging modalities has been symmetrically validated to precisely detect TCFA in vivo, since any single imaging modality exhibit natural limitations when characterizing the elusive TCFA. Therefore, integration of theses imaging modalities into a single catheter is hypothesized to be the optimal method to enable the early detection of TCFA by combing best features of these techniques while compensating their respective weakness. ❧ In this thesis, several multi-modality intravascular imaging systems by combined use of ultrasonic and optical techniques were developed in three aspects to access the morphological information, functional components, and elasticity of coronary arteries. Aim to fully obtain the morphological information real time in vivo, an ultra-high speed integrated intravascular ultrasound (IVUS) and optical coherence tomography (OCT) system has been optimized and prototyped. Statistical validation study and IVUS-OCT diagnostic criteria development has demonstrated that the integrated IVUS-OCT system has an overall higher diagnostic accuracy of atherosclerotic plaques, especially for lipid-rich plaques. From the cost-effective perspectives, a multi-frequency IVUS imaging system was developed to improve the trade-off between resolution and depth of penetration of IVUS. Aiming to measure the thin fibrous cap, an ultra-high frequency IVUS transducer was incorporated into the conventional IVUS catheter to provide higher special resolution image of the coronary artery, which makes the multi-frequency IVUS imaging system an alternative of integrated IVUS-OCT system. Moreover, the development of a high speed integrated IVUS and intravascular photoacoustic (IVPA) system make it possible to quantify a key parameter of diagnosing TCFA—the size of lipid deposition inside coronary artery. In vitro imaging of lipid-laden artery was performed by using current IVUS-IVPA system with 2 orders of magnitude improvement of imaging speed, which bridged the gap of translating the IVUS-IVPA technology to clinical study. In order to characterized the biomechanical properties of plaque components, acoustic radiation force (ARF) optical coherence elastography (OCE) is further developed featured by the confocal alignment of OCT detection region with acoustic excitation field. Based on the… Advisors/Committee Members: Shung, Kirk KopingZhou, Qifa (Committee Chair), Yen, Jesse (Committee Member), Armani, Andrea M. (Committee Member), McCain, Megan (Committee Member).

Subjects/Keywords: atherosclerosis; intravascular imaging; intravascular ultrasound; high frequency ultrasound; multi-modality imaging; photoacoustic imaging

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APA (6^th Edition):

Ma, T. (2017). Multi-modality intravascular imaging by combined use of ultrasonic and opticial techniques. (Doctoral Dissertation). University of Southern California. Retrieved from http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/616089/rec/4247

Chicago Manual of Style (16^th Edition):

Ma, Teng. “Multi-modality intravascular imaging by combined use of ultrasonic and opticial techniques.” 2017. Doctoral Dissertation, University of Southern California. Accessed December 07, 2019. http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/616089/rec/4247.

MLA Handbook (7^th Edition):

Ma, Teng. “Multi-modality intravascular imaging by combined use of ultrasonic and opticial techniques.” 2017. Web. 07 Dec 2019.

Vancouver:

Ma T. Multi-modality intravascular imaging by combined use of ultrasonic and opticial techniques. [Internet] [Doctoral dissertation]. University of Southern California; 2017. [cited 2019 Dec 07]. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/616089/rec/4247.

Council of Science Editors:

Ma T. Multi-modality intravascular imaging by combined use of ultrasonic and opticial techniques. [Doctoral Dissertation]. University of Southern California; 2017. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/616089/rec/4247

Wayne State University

10. Williams, Rachael Joymarie. The Influence Of Gestural Learning On Oral Reading And Reading Comprehension.

Degree: MS, Communication Sciences and Disorders, 2014, Wayne State University

URL: https://digitalcommons.wayne.edu/oa_theses/322

► The purpose of this study is to evaluate how gestural training may facilitate oral reading and reading comprehension of single words. For example, it… (more)

▼ The purpose of this study is to evaluate how gestural training may facilitate oral reading and reading comprehension of single words. For example, it is not clear whether multi-modal cues such as gesture provide an advantage over verbal cueing alone, or which type of multi-modal cues may be more effective than others in visual-verbal learning. This study examined language learning in healthy volunteers to be able to apply the effective methods for language intervention in individuals with language difficulties. Thirty-two healthy adults were selected to participate in four different learning conditions including verbal alone, visual cue, meaningful gesture, and meaningless gesture. The participants were trained to correlate a verb with the matched nonsense symbol(s). After the 4 training conditions, the participants completed a final comprehensive yes/no verification task. It was predicted that participants would perform most accurately in orally reading novel script that was trained using meaningful gesture, followed by training with the visual tracing cue, then verbal training alone, and finally, verbal plus meaningless gesture. It was also predicted that participants would perform fastest in orally reading novel script that was trained using meaningful gesture, followed by training with the visual tracing cue, then verbal training alone, and finally, verbal plus meaningless gesture. The results of this study did not support the assumption that training with meaningful gestures facilitates learning of visual-verbal associations more than verbal training alone. Also, the assumption that training with a visual tracing gesture would aid learning more than training with the verbal cue alone was not supported by this study. The assumption that training with meaningless gestures would interfere with learning compared to training with the verbal cue only was supported by this study. These results suggest that the addition of a gesture with the verbal production of the word divides the participants' attention between two items rather than one. These results also suggest that the nonsense symbols were vastly unfamiliar and therefore taxing the process of language learning. It would be beneficial for future studies to use the theory of these training tasks with young children who have increased mental flexibility and are better able to learn language when using combined gestures and/or movement with verbal production of words. Advisors/Committee Members: Margart Greenwald.

Subjects/Keywords: Multi-Modality; Oral Reading; Reading Comprehension; Word Learning; Speech and Hearing Science

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APA (6^th Edition):

Williams, R. J. (2014). The Influence Of Gestural Learning On Oral Reading And Reading Comprehension. (Masters Thesis). Wayne State University. Retrieved from https://digitalcommons.wayne.edu/oa_theses/322

Chicago Manual of Style (16^th Edition):

Williams, Rachael Joymarie. “The Influence Of Gestural Learning On Oral Reading And Reading Comprehension.” 2014. Masters Thesis, Wayne State University. Accessed December 07, 2019. https://digitalcommons.wayne.edu/oa_theses/322.

MLA Handbook (7^th Edition):

Williams, Rachael Joymarie. “The Influence Of Gestural Learning On Oral Reading And Reading Comprehension.” 2014. Web. 07 Dec 2019.

Vancouver:

Williams RJ. The Influence Of Gestural Learning On Oral Reading And Reading Comprehension. [Internet] [Masters thesis]. Wayne State University; 2014. [cited 2019 Dec 07]. Available from: https://digitalcommons.wayne.edu/oa_theses/322.

Council of Science Editors:

Williams RJ. The Influence Of Gestural Learning On Oral Reading And Reading Comprehension. [Masters Thesis]. Wayne State University; 2014. Available from: https://digitalcommons.wayne.edu/oa_theses/322

University of Michigan

11. Sinha, Sumedha Prashant. Breast Cancer Detection on Automated 3D Ultrasound with Co-localized 3D X-ray.

Degree: PhD, Biomedical Engineering, 2010, University of Michigan

URL: http://hdl.handle.net/2027.42/78947

► X-ray mammography is the gold standard for detecting breast cancer while B-mode ultrasound is employed as its diagnostic complement. This dissertation aimed at acquiring a… (more)

▼ X-ray mammography is the gold standard for detecting breast cancer while B-mode ultrasound is employed as its diagnostic complement. This dissertation aimed at acquiring a high quality, high-resolution 3D automated ultrasound image of the entire breast at current diagnostic frequencies, in the same geometry as mammography and its 3D equivalent, digital breast tomosynthesis, and to extend and help test its utility with co-localization. The first objective of this work was to engineer solutions to overcome some challenges inherent in acquiring complete automated ultrasound of the breast and minimizing patient motion during scans. Automated whole-breast ultrasound that can be registered to X-Ray imaging eliminates the uncertainty associated with hand-held ultrasound. More than 170 subjects were imaged using superior coupling agents tested during the course of this study. At least one radiologist rated the usefulness of X-Ray and ultrasound co-localization as high in the majority of our study cases. The second objective was to accurately register tomosynthesis image volumes of the breast, making the detection of tissue growth and deformation over time a realistic possibility. It was found for the first time to our knowledge that whole breast digital tomosynthesis image volumes can be spatially registered with an error tolerance of 2 mm, which is 10% of the average size of cancers in a screening population. The third and final objective involved the registration and fusion of 3D ultrasound image volumes acquired from opposite sides of the breast in the mammographic geometry, a novel technique that improves the volumetric resolution of high frequency ultrasound but poses unique problems. To improve the accuracy and speed of registration, direction-dependent artifacts should be eliminated. Further, it is necessary to identify other regions, usually at greater depths, that contain little or misleading information. Machine learning, principal component analysis and speckle reducing anisotropic diffusion were tested in this context. We showed that machine learning classifiers can identify regions of corrupted data accurately on a custom breast-mimicking phantom, and also that they can identify specific artifacts in-vivo. Initial registrations of phantom image sets with many regions of artifacts removed provided robust results as compared to the original datasets. Advisors/Committee Members: Carson, Paul L. (committee member), Fessler, Jeffrey A. (committee member), Fowlkes, J Brian (committee member), Goodsitt, Mitchell M. (committee member).

Subjects/Keywords: Breast Cancer Detection; Automated 3D Ultrasound; Multi-modality Imaging; 3D Tomosynthesis; Biomedical Engineering; Engineering

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sinha, S. P. (2010). Breast Cancer Detection on Automated 3D Ultrasound with Co-localized 3D X-ray. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/78947

Chicago Manual of Style (16^th Edition):

Sinha, Sumedha Prashant. “Breast Cancer Detection on Automated 3D Ultrasound with Co-localized 3D X-ray.” 2010. Doctoral Dissertation, University of Michigan. Accessed December 07, 2019. http://hdl.handle.net/2027.42/78947.

MLA Handbook (7^th Edition):

Sinha, Sumedha Prashant. “Breast Cancer Detection on Automated 3D Ultrasound with Co-localized 3D X-ray.” 2010. Web. 07 Dec 2019.

Vancouver:

Sinha SP. Breast Cancer Detection on Automated 3D Ultrasound with Co-localized 3D X-ray. [Internet] [Doctoral dissertation]. University of Michigan; 2010. [cited 2019 Dec 07]. Available from: http://hdl.handle.net/2027.42/78947.

Council of Science Editors:

Sinha SP. Breast Cancer Detection on Automated 3D Ultrasound with Co-localized 3D X-ray. [Doctoral Dissertation]. University of Michigan; 2010. Available from: http://hdl.handle.net/2027.42/78947

University of Sydney

12. Kumar, Ashnil. A graph-based approach for the retrieval of multi-modality medical images .

Degree: 2013, University of Sydney

URL: http://hdl.handle.net/2123/9343

► Medical imaging has revolutionised modern medicine and is now an integral aspect of diagnosis and patient monitoring. The development of new imaging devices for a… (more)

▼ Medical imaging has revolutionised modern medicine and is now an integral aspect of diagnosis and patient monitoring. The development of new imaging devices for a wide variety of clinical cases has spurred an increase in the data volume acquired in hospitals. These large data collections offer opportunities for search-based applications in evidence-based diagnosis, education, and biomedical research. However, conventional search methods that operate upon manual annotations are not feasible for this data volume. Content-based image retrieval (CBIR) is an image search technique that uses automatically derived visual features as search criteria and has demonstrable clinical benefits. However, very few studies have investigated the CBIR of multi-modality medical images, which are making a monumental impact in healthcare, e.g., combined positron emission tomography and computed tomography (PET-CT) for cancer diagnosis. In this thesis, we propose a new graph-based method for the CBIR of multi-modality medical images. We derive a graph representation that emphasises the spatial relationships between modalities by structurally constraining the graph based on image features, e.g., spatial proximity of tumours and organs. We also introduce a graph similarity calculation algorithm that prioritises the relationships between tumours and related organs. To enable effective human interpretation of retrieved multi-modality images, we also present a user interface that displays graph abstractions alongside complex multi-modality images. Our results demonstrated that our method achieved a high precision when retrieving images on the basis of tumour location within organs. The evaluation of our proposed UI design by user surveys revealed that it improved the ability of users to interpret and understand the similarity between retrieved PET-CT images. The work in this thesis advances the state-of-the-art by enabling a novel approach for the retrieval of multi-modality medical images.

Subjects/Keywords: content-based image retrieval; graph algorithms; medical imaging; multi-modality imaging; PET-CT

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APA (6^th Edition):

Kumar, A. (2013). A graph-based approach for the retrieval of multi-modality medical images . (Thesis). University of Sydney. Retrieved from http://hdl.handle.net/2123/9343

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kumar, Ashnil. “A graph-based approach for the retrieval of multi-modality medical images .” 2013. Thesis, University of Sydney. Accessed December 07, 2019. http://hdl.handle.net/2123/9343.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kumar, Ashnil. “A graph-based approach for the retrieval of multi-modality medical images .” 2013. Web. 07 Dec 2019.

Vancouver:

Kumar A. A graph-based approach for the retrieval of multi-modality medical images . [Internet] [Thesis]. University of Sydney; 2013. [cited 2019 Dec 07]. Available from: http://hdl.handle.net/2123/9343.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kumar A. A graph-based approach for the retrieval of multi-modality medical images . [Thesis]. University of Sydney; 2013. Available from: http://hdl.handle.net/2123/9343

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

13. Liu, Xinwei. Multi-modality quality assessment for unconstrained biometric samples : Évaluation de la qualité multimodale pour des échantillons biométriques non soumis à des contraintes.

Degree: Docteur es, Informatique, 2018, Normandie; Gjøvik University College (Norvège)

URL: http://www.theses.fr/2018NORMC284

► L’objectif de ces travaux de recherche est d’étudier les méthodes d’évaluation de laqualité des images biométriques multimodales sur des échantillons acquis de manièrenon contrainte. De… (more)

▼ L’objectif de ces travaux de recherche est d’étudier les méthodes d’évaluation de laqualité des images biométriques multimodales sur des échantillons acquis de manièrenon contrainte. De nombreuses s études ont noté l’importance de la qualité del’échantillon pour un système de reconnaissance ou un algorithme de comparaison,puisque la performance du système biométrique est intrinsèquement dépendant dela qualité des images de l’échantillon. Dès lors, la nécessité d’évaluer la qualitédes échantillons biométriques pour plusieurs modalités (empreintes digitales, iris,visage, etc.) est devenue primordiale notamment avec l’apparition de systèmesbiométriques multimodaux de haute précision.Après une introduction présentant un historique de la biométrie et des préceptesliés à la qualité des échantillons biométriques, nous présentons le concept d’évaluationde la qualité des échantillons pour plusieurs modalités. Les normes de qualitéISO / CEI récemment établies pour les empreintes digitales, l’iris et le visage sontprésentées. De plus, des approches d’évaluation de la qualité des échantillons conçuesspécifiquement pour les empreintes digitales avec et sans contact, pour l’iris(dont une image est capturée en proche infrarouge et dans le domaine visible),ainsi que le visage sont étudiées. Finalement, des techniques d’évaluation des performancesdes mesures de qualité des échantillons biométriques sont égalementétudiées.Sur la base des conclusions formulées suite à l’étude des solutions algorithmiques portant sur l’évaluation de la qualité des échantillons biométriques, nous proposonsun cadre commun pour l’évaluation de la qualité d’image biométrique pourplusieurs modalité. Après avoir étudié les attributs de qualité basés sur l’image parmodalité biométrique, nous examinons quelle intersection existe pour l’ensembledes modalités. Ensuite, nous sélectionnons et redéfinissons les attributs de qualitébasés sur l’image qui sont les plus importants afin de définir un cadre commun.Afin de relier ces attributs de qualité aux vrais échantillons biométriques,nous développons une nouvelle base de données de qualité d’image biométriquemulti-modalité qui contient des images échantillons de haute qualité et des imagesdégradées pour l’empreinte digitale acquise sans contact, l’iris (dont l’acquisitionest réalisée dans le spectre visible) et le visage. Les types de dégradation appliquéssont liés aux attributs de qualité qui sont communs aux diverses modalitéset qui sont basés sur l’image. Un autre aspect important du cadre commun proposéest la qualité de l’image et ses applications en biométrie. Nous avons d’abordintroduit et classifié les métriques de qualité d’image existantes, puis effectué unbref aperçu des métriques de qualité d’image sans référence, qui peuvent être appliquéespour l’évaluation de la qualité des échantillons biométriques. De plus, nousétudions comment les mesures de qualité d’image sans référence ont été utiliséespour l’évaluation de la qualité des empreintes digitales, de l’iris et des modalitésbiométriques du visage.Des… Advisors/Committee Members: Charrier, Christophe (thesis director).

Subjects/Keywords: Évaluation de la qualité de l'image; Multimodalité; Image quality assessment; Biometrics; Multi-modality

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Liu, X. (2018). Multi-modality quality assessment for unconstrained biometric samples : Évaluation de la qualité multimodale pour des échantillons biométriques non soumis à des contraintes. (Doctoral Dissertation). Normandie; Gjøvik University College (Norvège). Retrieved from http://www.theses.fr/2018NORMC284

Chicago Manual of Style (16^th Edition):

Liu, Xinwei. “Multi-modality quality assessment for unconstrained biometric samples : Évaluation de la qualité multimodale pour des échantillons biométriques non soumis à des contraintes.” 2018. Doctoral Dissertation, Normandie; Gjøvik University College (Norvège). Accessed December 07, 2019. http://www.theses.fr/2018NORMC284.

MLA Handbook (7^th Edition):

Liu, Xinwei. “Multi-modality quality assessment for unconstrained biometric samples : Évaluation de la qualité multimodale pour des échantillons biométriques non soumis à des contraintes.” 2018. Web. 07 Dec 2019.

Vancouver:

Liu X. Multi-modality quality assessment for unconstrained biometric samples : Évaluation de la qualité multimodale pour des échantillons biométriques non soumis à des contraintes. [Internet] [Doctoral dissertation]. Normandie; Gjøvik University College (Norvège); 2018. [cited 2019 Dec 07]. Available from: http://www.theses.fr/2018NORMC284.

Council of Science Editors:

Liu X. Multi-modality quality assessment for unconstrained biometric samples : Évaluation de la qualité multimodale pour des échantillons biométriques non soumis à des contraintes. [Doctoral Dissertation]. Normandie; Gjøvik University College (Norvège); 2018. Available from: http://www.theses.fr/2018NORMC284

University of Washington

14. Samareh Abolhasani, Banafsheh. Contemporaneous Health Monitoring and Biomarker Discovery by Integration of Patient Data and Disease Knowledge.

Degree: PhD, 2019, University of Washington

URL: http://hdl.handle.net/1773/44834

► Technological innovations have given rise to data-rich environments that support the use of heterogeneous sensor measurements to monitor complex healthcare systems. Despite these advancements, however,… (more)

▼ Technological innovations have given rise to data-rich environments that support the use of heterogeneous sensor measurements to monitor complex healthcare systems. Despite these advancements, however, there remains little understanding of how patient health evolves in real clinical settings and how changes in health condition generate manifestations that are captured by the data. To address this knowledge gap, my research aims to build disease trajectory modeling that can reconstruct the evolving patient’s health condition over time, termed the contemporaneous health index (CHI), by combining data and the natural history model of the disease. This global index may help increase the continuity of care, facilitate patient-provider communication, and assist with a range of clinical decision makings. However, lack of deep understanding of the disease and its progression, existence of patient heterogeneity, inherent uncertainty in predictive models and the emergence of large amounts of complex, and unstructured data, all could compromise prediction capabilities. In this dissertation, we developed innovative methodologies that reflect the progression of the underlying patient condition by learning personalized models, quantifying the uncertainty of those models, and creating effective biomarker engineering pipelines to analyze large amounts of complex data for effective incorporation into the calculation of CHI. We first, proposed a novel clinical data fusion framework, named DL-CHI: a dictionary learning-based CHI that quantifies the severity of the deterioration process over time and represents monotonic progression patterns with a systematic optimization formulation. DL-CHI mitigated the heterogeneity of the patients by incorporating dictionary learning to create personalized models for individual patients. We then developed the UQ-CHI framework: an uncertainty quantification-based model of CHI to further enhance the disease trajectory modeling with uncertainty quantification by considering imperfect and continuous delivery of knowledge via probabilistic nature of maximum entropy discrimination (MED) principle. Finally, we proposed effective biomarker engineering pipelines to enable possible extensions of the CHI for building trajectory models from complex data (video, audio, text, and mobile sensor reading data). We applied the proposed methodologies to real-world applications, including Alzheimer’s disease (AD), surgical site infection (SSI), depression and human activity recognition using wearable sensors Advisors/Committee Members: Huang, Shuai (advisor).

Subjects/Keywords: Bayesian; Convex optimization; Machine learning; Multi-modality frameworks; Uncertainty quantification; Industrial engineering; Industrial engineering

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APA (6^th Edition):

Samareh Abolhasani, B. (2019). Contemporaneous Health Monitoring and Biomarker Discovery by Integration of Patient Data and Disease Knowledge. (Doctoral Dissertation). University of Washington. Retrieved from http://hdl.handle.net/1773/44834

Chicago Manual of Style (16^th Edition):

Samareh Abolhasani, Banafsheh. “Contemporaneous Health Monitoring and Biomarker Discovery by Integration of Patient Data and Disease Knowledge.” 2019. Doctoral Dissertation, University of Washington. Accessed December 07, 2019. http://hdl.handle.net/1773/44834.

MLA Handbook (7^th Edition):

Samareh Abolhasani, Banafsheh. “Contemporaneous Health Monitoring and Biomarker Discovery by Integration of Patient Data and Disease Knowledge.” 2019. Web. 07 Dec 2019.

Vancouver:

Samareh Abolhasani B. Contemporaneous Health Monitoring and Biomarker Discovery by Integration of Patient Data and Disease Knowledge. [Internet] [Doctoral dissertation]. University of Washington; 2019. [cited 2019 Dec 07]. Available from: http://hdl.handle.net/1773/44834.

Council of Science Editors:

Samareh Abolhasani B. Contemporaneous Health Monitoring and Biomarker Discovery by Integration of Patient Data and Disease Knowledge. [Doctoral Dissertation]. University of Washington; 2019. Available from: http://hdl.handle.net/1773/44834

University of Iowa

15. Halaweish, Ahmed Fathi. Exploration of multi-volumetric hyperpolarized 3Helium MRI: cross-correlation with quantitative MDCT.

Degree: PhD, Biomedical Engineering, 2011, University of Iowa

URL: https://ir.uiowa.edu/etd/2711

► Hyperpolarized 3Helium (HP 3He) magnetic resonance imaging (MRI) has provided considerable insights into the anatomical structures and localized physiological phenomenon involved in pulmonary ventilation.… (more)

▼ Hyperpolarized 3Helium (HP 3He) magnetic resonance imaging (MRI) has provided considerable insights into the anatomical structures and localized physiological phenomenon involved in pulmonary ventilation. The increasing mortality rates of pulmonary diseases such as COPD, gives rise to the need for sensitive and regional assessments of early disease conditions in attempts to decrease mortality and improve lifestyles. Evaluation of the HP 3He MRI diffusion weighted measurements of lung microstructure, demonstrated a statistically significant relationship between microstructure expansion and degree of lung inflation at the time of imaging. The ability of HP 3He MRI to assess regional ventilation was validated against air volume change estimates of ventilation attainable via conventional MDCT in a cohort of 8 normal never smokers. Great correlations and slope were observed between the functional estimates, with similar gravitationally dependent-nondependent gradients throughout. A small but significant preferential helium distribution was observed in the nondependent regions, most likely due to gas density differences between air and helium. Further validation of HP 3He MRI's ability to assess regional ventilation, was carried via quantitative and qualitative assessments against xenon-enhanced MDCT (normal = 4, COPD = 2). The MRI based estimates were found to be insensitive to slow and fast ventilating regions, while superior in exhibiting ventilation defects. Similar gravitationally dependent - nondependent gradients were observed throughout, along with a homogenous distribution of the exogenous contrast agents. Coefficient of variation (COV) values followed similar trends in the normal subjects, while only one COPD subject demonstrated an increase from the normal population baseline. Acquisition differences including single vs. multi-breath and z-axis coverage could attribute to the quantitative differences observed. Evaluation of the density dependent distribution patterns of helium in a normal airway model via dynamic HP 3He MRI and computational fluid dynamics, demonstrated an increased preferential distribution in the nondependent airways, in agreement with the ventilation discrepancies previously observed. In combination with the developmental aspects of the presented research, we have validated the ability of HP 3He MRI to assess regional ventilation, via multiple quantitative assessments against conventional based and exogenously enhanced MDCT techniques and extracted the lung inflation level dependencies. Complimented with dynamic imaging and CFD simulations of helium distribution, these results provide insight into future considerations critical to the establishment of the technique as a surrogate to the ionizing radiation based modalities. Advisors/Committee Members: Hoffman, Eric A. (supervisor).

Subjects/Keywords: distribution; hyperpolarized helium; lung imaging; multi-modality; pulmonary; volume control; Biomedical Engineering and Bioengineering

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APA (6^th Edition):

Halaweish, A. F. (2011). Exploration of multi-volumetric hyperpolarized 3Helium MRI: cross-correlation with quantitative MDCT. (Doctoral Dissertation). University of Iowa. Retrieved from https://ir.uiowa.edu/etd/2711

Chicago Manual of Style (16^th Edition):

Halaweish, Ahmed Fathi. “Exploration of multi-volumetric hyperpolarized 3Helium MRI: cross-correlation with quantitative MDCT.” 2011. Doctoral Dissertation, University of Iowa. Accessed December 07, 2019. https://ir.uiowa.edu/etd/2711.

MLA Handbook (7^th Edition):

Halaweish, Ahmed Fathi. “Exploration of multi-volumetric hyperpolarized 3Helium MRI: cross-correlation with quantitative MDCT.” 2011. Web. 07 Dec 2019.

Vancouver:

Halaweish AF. Exploration of multi-volumetric hyperpolarized 3Helium MRI: cross-correlation with quantitative MDCT. [Internet] [Doctoral dissertation]. University of Iowa; 2011. [cited 2019 Dec 07]. Available from: https://ir.uiowa.edu/etd/2711.

Council of Science Editors:

Halaweish AF. Exploration of multi-volumetric hyperpolarized 3Helium MRI: cross-correlation with quantitative MDCT. [Doctoral Dissertation]. University of Iowa; 2011. Available from: https://ir.uiowa.edu/etd/2711

University of Tasmania

16. Pathan, F. The role of advanced cardiovascular Imaging in the management of the new cardiovascular epidemics of old age.

Degree: 2019, University of Tasmania

URL: Pathan, F ORCID: 0000-0002-0939-5470 <https://orcid.org/0000-0002-0939-5470> 2019 , 'The role of advanced cardiovascular Imaging in the management of the new cardiovascular epidemics of old age', PhD thesis, University of Tasmania.

► The ageing population, greater survival following acute myocardial infarction and a greater prevalence of risk factors have all contributed to the emerging epidemics of Atrial… (more)

▼ The ageing population, greater survival following acute myocardial infarction and a greater prevalence of risk factors have all contributed to the emerging epidemics of Atrial Fibrillation (AF) and Heart Failure with Preserved Ejection Fraction (HFpEF). At the same time, the landscape of cardiovascular imaging has shifted from echocardiography alone to one of multi-modality imaging. The combination of these developments has contributed to an increase in inappropriate use of cardiac investigations which, in its own right is an iatrogenic cardiovascular epidemic. An understanding of how best to utilise these technological advances with respect to optimal management of AF and HFpEF requires an evaluation of literature and experimental evaluation of their respective utilities. The integration of advances in echocardiography (such as myocardial strain), Cardiac Computed Tomography (CT) and Cardiac Magnetic Resonance (CMR) into current diagnostic pathways will improve our ability to evaluate presence of disease, enable comprehensive characterisation of both AF and HFpEF and also enable prognostication of future events. I seek to determine the roles of Echocardiography, Cardiac CT and CMR with respect to AF and HFpEF. I also aim to use imaging advances to address the epidemic of inappropriate use. The goal of this thesis is to determine how advances in cardiac imaging can be integrated to improve management of cardiovascular epidemics both clinical (AF and HFpEF) and systemic/iatrogenic (inappropriate use). I have divided my PhD thesis into 3 interconnected parts with each part informing the next. Firstly I present a review of current imaging modalities, recent advancements and their roles in the management of AF and HFpEF. Having reviewed the landscape of current advances and how they may contribute to management of the current epidemics of HFpEF, AF, in part 2, I seek to address some barriers and limitations: 1.) Availability, cost and speed of CMR, 2.) The limitations of CMR in evaluating diastolic function in HFpEF 3.) The need to assess atrial function non-invasively and predict AF using atrial strain Which is currently limited by a.) by a lack of consensus on normal references ranges for atrial strain b.) A lack of understanding about inter vendor and inter modality differences Finally, in part 3, informed by the literature reviews and validation data, I seek to employ 2 advances (namely, atrial strain and Hand Held ultrasonography (HHU)) to demonstrate improved efficiency based on information gained, improved service delivery and reduced cost. All statistical analysis was performed on IBM SPSS Statistics version 24 (SPSS, Chicago, IL, USA), R (The R project) and correlation/ Bland-Altman plots were created on MedCalc® Version 17.9.7(MedCalc Ostend, Belgium). The literature reviews show that in addition to the existing role of echocardiography there is a growing body of evidence for the role of Cardiac CT in the management of AF and an underutilised role for CMR in the diagnosis, phenotyping and management…

Subjects/Keywords: multi modality cardiovascular imaging; atrial fibrillation; heart failure with preserved ejection fraction; atrial strain

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APA (6^th Edition):

Pathan, F. (2019). The role of advanced cardiovascular Imaging in the management of the new cardiovascular epidemics of old age. (Thesis). University of Tasmania. Retrieved from Pathan, F ORCID: 0000-0002-0939-5470 <https://orcid.org/0000-0002-0939-5470> 2019 , 'The role of advanced cardiovascular Imaging in the management of the new cardiovascular epidemics of old age', PhD thesis, University of Tasmania.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Pathan, F. “The role of advanced cardiovascular Imaging in the management of the new cardiovascular epidemics of old age.” 2019. Thesis, University of Tasmania. Accessed December 07, 2019. Pathan, F ORCID: 0000-0002-0939-5470 <https://orcid.org/0000-0002-0939-5470> 2019 , 'The role of advanced cardiovascular Imaging in the management of the new cardiovascular epidemics of old age', PhD thesis, University of Tasmania..

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Pathan, F. “The role of advanced cardiovascular Imaging in the management of the new cardiovascular epidemics of old age.” 2019. Web. 07 Dec 2019.

Vancouver:

Pathan F. The role of advanced cardiovascular Imaging in the management of the new cardiovascular epidemics of old age. [Internet] [Thesis]. University of Tasmania; 2019. [cited 2019 Dec 07]. Available from: Pathan, F ORCID: 0000-0002-0939-5470 <https://orcid.org/0000-0002-0939-5470> 2019 , 'The role of advanced cardiovascular Imaging in the management of the new cardiovascular epidemics of old age', PhD thesis, University of Tasmania..

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Pathan F. The role of advanced cardiovascular Imaging in the management of the new cardiovascular epidemics of old age. [Thesis]. University of Tasmania; 2019. Available from: Pathan, F ORCID: 0000-0002-0939-5470 <https://orcid.org/0000-0002-0939-5470> 2019 , 'The role of advanced cardiovascular Imaging in the management of the new cardiovascular epidemics of old age', PhD thesis, University of Tasmania.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Oxford

17. Heinrich, Mattias Paul. Deformable lung registration for pulmonary image analysis of MRI and CT scans.

Degree: PhD, 2013, University of Oxford

URL: http://ora.ox.ac.uk/objects/uuid:570112d9-c995-46df-86c0-15ce4ab928ff ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.581327

► Medical imaging has seen a rapid development in its clinical use in assessment of treatment outcome, disease monitoring and diagnosis over the last few decades.… (more)

Subjects/Keywords: 616.07548; Biomedical engineering; Image understanding; Pattern recognition (statistics); medical image analysis; image registration; respiratory motion; multi-modality fusion

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APA (6^th Edition):

Heinrich, M. P. (2013). Deformable lung registration for pulmonary image analysis of MRI and CT scans. (Doctoral Dissertation). University of Oxford. Retrieved from http://ora.ox.ac.uk/objects/uuid:570112d9-c995-46df-86c0-15ce4ab928ff ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.581327

Chicago Manual of Style (16^th Edition):

Heinrich, Mattias Paul. “Deformable lung registration for pulmonary image analysis of MRI and CT scans.” 2013. Doctoral Dissertation, University of Oxford. Accessed December 07, 2019. http://ora.ox.ac.uk/objects/uuid:570112d9-c995-46df-86c0-15ce4ab928ff ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.581327.

MLA Handbook (7^th Edition):

Heinrich, Mattias Paul. “Deformable lung registration for pulmonary image analysis of MRI and CT scans.” 2013. Web. 07 Dec 2019.

Vancouver:

Heinrich MP. Deformable lung registration for pulmonary image analysis of MRI and CT scans. [Internet] [Doctoral dissertation]. University of Oxford; 2013. [cited 2019 Dec 07]. Available from: http://ora.ox.ac.uk/objects/uuid:570112d9-c995-46df-86c0-15ce4ab928ff ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.581327.

Council of Science Editors:

Heinrich MP. Deformable lung registration for pulmonary image analysis of MRI and CT scans. [Doctoral Dissertation]. University of Oxford; 2013. Available from: http://ora.ox.ac.uk/objects/uuid:570112d9-c995-46df-86c0-15ce4ab928ff ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.581327

Kent State University

18. Tollafield, Karen Andrus. Writing Matters: Understanding the Writing Practices of Five Young Adults Self-Identifying on the LGBTQ Spectrum.

Degree: PhD, College and Graduate School of Education, Health and Human Services / School of Teaching, Learning and Curriculum Studies, 2016, Kent State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=kent1468267685

► TOLLAFIELD, KAREN ANDRUS, Ph.D., August 2016TEACHING, LEARNINGAND CURRICULUM STUDIESWRITING MATTERS: UNDERSTANDING THE WRITING PRACTICES OF FIVE YOUNG ADULTS SELF-IDENTIFYING ON THE LGBTQ SPECTRUM (450 pp.)Dissertation… (more)

Subjects/Keywords: Literacy; Language Arts; Composition; Curricula; Education; Gender; Glbt Studies; Multimedia Communications; writing; literacy; language arts; curricula; LGBTQ; multi-modality; education

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Tollafield, K. A. (2016). Writing Matters: Understanding the Writing Practices of Five Young Adults Self-Identifying on the LGBTQ Spectrum. (Doctoral Dissertation). Kent State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=kent1468267685

Chicago Manual of Style (16^th Edition):

Tollafield, Karen Andrus. “Writing Matters: Understanding the Writing Practices of Five Young Adults Self-Identifying on the LGBTQ Spectrum.” 2016. Doctoral Dissertation, Kent State University. Accessed December 07, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=kent1468267685.

MLA Handbook (7^th Edition):

Tollafield, Karen Andrus. “Writing Matters: Understanding the Writing Practices of Five Young Adults Self-Identifying on the LGBTQ Spectrum.” 2016. Web. 07 Dec 2019.

Vancouver:

Tollafield KA. Writing Matters: Understanding the Writing Practices of Five Young Adults Self-Identifying on the LGBTQ Spectrum. [Internet] [Doctoral dissertation]. Kent State University; 2016. [cited 2019 Dec 07]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=kent1468267685.

Council of Science Editors:

Tollafield KA. Writing Matters: Understanding the Writing Practices of Five Young Adults Self-Identifying on the LGBTQ Spectrum. [Doctoral Dissertation]. Kent State University; 2016. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=kent1468267685

University of California – Irvine

19. Luk, Alex T. A TRUE MULTI-MODALITY SYSTEM FOR OPTICAL IMAGING WITH MR RESOLUTION: PHOTO-MAGNETIC IMAGING.

Degree: Electrical and Computer Engineering, 2016, University of California – Irvine

URL: http://www.escholarship.org/uc/item/1fm9f5vw

► A major goal of in vivo imaging is to obtain individualized structural, functional, and molecular information to provide personalized medicine. In particular, optical imaging uses… (more)

▼ A major goal of in vivo imaging is to obtain individualized structural, functional, and molecular information to provide personalized medicine. In particular, optical imaging uses non-ionizing radiation to provide functional information such as hemoglobin concentration and also visualize exogenous contrast agents as well as molecular and functional markers. Indeed, in vivo optical imaging extends across a wide range of applications, from cellular to organ levels. At high end of the spectrum, diffuse optical tomography (DOT) can penetrate up to 10 centimeters but only offer low-resolution images (> 5mm) due to highly scattering nature of the tissue. Significant effort has been spent on multi-modality imaging techniques to improve the resolution of DOT. While combining DOT with spatial information defined by a separate anatomical imaging modality is promising, there are many challenges and inaccuracies that arise with co-registration. However this can be overcome with a novel multi-modality imaging technique, Photo-Magnetic Imaging (PMI) which uses MRI as a detector to provide both high resolution anatomical and optical information. PMI takes advantage of the 3D measurement capabilities of MR thermometry (MRT) to non-invasively measure the temperature increase of the medium induced by a laser to acquire a temperature map of the entire volume. As DOT measures the photon flux only from the boundary, the major advantage of PMI is that high absorbing regions can be resolved directly from the high spatial resolution temperature map. These measurements can then be converted to obtain the optical absorption properties of the tissue using a reconstruction algorithm to model the light propagation and heat transfer in tissue. This thesis will present the development of the first preclinical in vivo small animal PMI system prototype using the safety standards set by the American National Standard Institution. To optimize the system for in vivo studies, a fast PMI reconstruction method was also developed to accelerate the original PMI reconstruction method ~1000 times faster. These promising results validated the practicality of PMI for preclinical studies and showed the potential of PMI for clinical studies. This led to the development of the first human PMI prototype for clinical breast studies.

Subjects/Keywords: Medical imaging; Electrical engineering; Biomedical engineering; diffuse optical tomography; magnetic resonance imaging; medical imaging; multi-modality; non-invasive; non-radiative

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APA (6^th Edition):

Luk, A. T. (2016). A TRUE MULTI-MODALITY SYSTEM FOR OPTICAL IMAGING WITH MR RESOLUTION: PHOTO-MAGNETIC IMAGING. (Thesis). University of California – Irvine. Retrieved from http://www.escholarship.org/uc/item/1fm9f5vw

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Luk, Alex T. “A TRUE MULTI-MODALITY SYSTEM FOR OPTICAL IMAGING WITH MR RESOLUTION: PHOTO-MAGNETIC IMAGING.” 2016. Thesis, University of California – Irvine. Accessed December 07, 2019. http://www.escholarship.org/uc/item/1fm9f5vw.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Luk, Alex T. “A TRUE MULTI-MODALITY SYSTEM FOR OPTICAL IMAGING WITH MR RESOLUTION: PHOTO-MAGNETIC IMAGING.” 2016. Web. 07 Dec 2019.

Vancouver:

Luk AT. A TRUE MULTI-MODALITY SYSTEM FOR OPTICAL IMAGING WITH MR RESOLUTION: PHOTO-MAGNETIC IMAGING. [Internet] [Thesis]. University of California – Irvine; 2016. [cited 2019 Dec 07]. Available from: http://www.escholarship.org/uc/item/1fm9f5vw.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Luk AT. A TRUE MULTI-MODALITY SYSTEM FOR OPTICAL IMAGING WITH MR RESOLUTION: PHOTO-MAGNETIC IMAGING. [Thesis]. University of California – Irvine; 2016. Available from: http://www.escholarship.org/uc/item/1fm9f5vw

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Georgia Tech

20. Park, Jong Seok. A multimodality CMOS cellular interfacing array for holistic cellular characterization and cell-based drug screening.

Degree: PhD, Electrical and Computer Engineering, 2017, Georgia Tech

URL: http://hdl.handle.net/1853/59259

► This thesis presents multimodality CMOS sensor and stimulator array for holistic cellular characterization and cell-based drug screening. Cells are the basic structural, functional, and biological… (more)

Subjects/Keywords: CMOS; Cells; Drug; Sensor; Multi modality; Stimulation; In vitro; Cardiomyocytes; Impedance; Optical sensing; Opacity; Potential recording; Electrode array

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APA (6^th Edition):

Park, J. S. (2017). A multimodality CMOS cellular interfacing array for holistic cellular characterization and cell-based drug screening. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/59259

Chicago Manual of Style (16^th Edition):

Park, Jong Seok. “A multimodality CMOS cellular interfacing array for holistic cellular characterization and cell-based drug screening.” 2017. Doctoral Dissertation, Georgia Tech. Accessed December 07, 2019. http://hdl.handle.net/1853/59259.

MLA Handbook (7^th Edition):

Park, Jong Seok. “A multimodality CMOS cellular interfacing array for holistic cellular characterization and cell-based drug screening.” 2017. Web. 07 Dec 2019.

Vancouver:

Park JS. A multimodality CMOS cellular interfacing array for holistic cellular characterization and cell-based drug screening. [Internet] [Doctoral dissertation]. Georgia Tech; 2017. [cited 2019 Dec 07]. Available from: http://hdl.handle.net/1853/59259.

Council of Science Editors:

Park JS. A multimodality CMOS cellular interfacing array for holistic cellular characterization and cell-based drug screening. [Doctoral Dissertation]. Georgia Tech; 2017. Available from: http://hdl.handle.net/1853/59259

University of Edinburgh

21. Wang, Chengjia. Development of registration methods for cardiovascular anatomy and function using advanced 3T MRI, 320-slice CT and PET imaging.

Degree: PhD, 2016, University of Edinburgh

URL: http://hdl.handle.net/1842/22918

► Different medical imaging modalities provide complementary anatomical and functional information. One increasingly important use of such information is in the clinical management of cardiovascular disease.… (more)

▼ Different medical imaging modalities provide complementary anatomical and functional information. One increasingly important use of such information is in the clinical management of cardiovascular disease. Multi-modality data is helping improve diagnosis accuracy, and individualize treatment. The Clinical Research Imaging Centre at the University of Edinburgh, has been involved in a number of cardiovascular clinical trials using longitudinal computed tomography (CT) and multi-parametric magnetic resonance (MR) imaging. The critical image processing technique that combines the information from all these different datasets is known as image registration, which is the topic of this thesis. Image registration, especially multi-modality and multi-parametric registration, remains a challenging field in medical image analysis. The new registration methods described in this work were all developed in response to genuine challenges in on-going clinical studies. These methods have been evaluated using data from these studies. In order to gain an insight into the building blocks of image registration methods, the thesis begins with a comprehensive literature review of state-of-the-art algorithms. This is followed by a description of the first registration method I developed to help track inflammation in aortic abdominal aneurysms. It registers multi-modality and multi-parametric images, with new contrast agents. The registration framework uses a semi-automatically generated region of interest around the aorta. The aorta is aligned based on a combination of the centres of the regions of interest and intensity matching. The method achieved sub-voxel accuracy. The second clinical study involved cardiac data. The first framework failed to register many of these datasets, because the cardiac data suffers from a common artefact of magnetic resonance images, namely intensity inhomogeneity. Thus I developed a new preprocessing technique that is able to correct the artefacts in the functional data using data from the anatomical scans. The registration framework, with this preprocessing step and new particle swarm optimizer, achieved significantly improved registration results on the cardiac data, and was validated quantitatively using neuro images from a clinical study of neonates. Although on average the new framework achieved accurate results, when processing data corrupted by severe artefacts and noise, premature convergence of the optimizer is still a common problem. To overcome this, I invented a new optimization method, that achieves more robust convergence by encoding prior knowledge of registration. The registration results from this new registration-oriented optimizer are more accurate than other general-purpose particle swarm optimization methods commonly applied to registration problems. In summary, this thesis describes a series of novel developments to an image registration framework, aimed to improve accuracy, robustness and speed. The resulting registration framework was applied to, and validated by, different types of…

Subjects/Keywords: 616.07; computed tomography; magnetic resonance imaging; image registration; registration software packages; multi-modality data; particle swarm optimizer

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APA (6^th Edition):

Wang, C. (2016). Development of registration methods for cardiovascular anatomy and function using advanced 3T MRI, 320-slice CT and PET imaging. (Doctoral Dissertation). University of Edinburgh. Retrieved from http://hdl.handle.net/1842/22918

Chicago Manual of Style (16^th Edition):

Wang, Chengjia. “Development of registration methods for cardiovascular anatomy and function using advanced 3T MRI, 320-slice CT and PET imaging.” 2016. Doctoral Dissertation, University of Edinburgh. Accessed December 07, 2019. http://hdl.handle.net/1842/22918.

MLA Handbook (7^th Edition):

Wang, Chengjia. “Development of registration methods for cardiovascular anatomy and function using advanced 3T MRI, 320-slice CT and PET imaging.” 2016. Web. 07 Dec 2019.

Vancouver:

Wang C. Development of registration methods for cardiovascular anatomy and function using advanced 3T MRI, 320-slice CT and PET imaging. [Internet] [Doctoral dissertation]. University of Edinburgh; 2016. [cited 2019 Dec 07]. Available from: http://hdl.handle.net/1842/22918.

Council of Science Editors:

Wang C. Development of registration methods for cardiovascular anatomy and function using advanced 3T MRI, 320-slice CT and PET imaging. [Doctoral Dissertation]. University of Edinburgh; 2016. Available from: http://hdl.handle.net/1842/22918

The Ohio State University

22. Kumar, Vidhya. Towards Multiorgan Characterization of Cardiometabolic Health and Disease.

Degree: PhD, Biomedical Sciences, 2018, The Ohio State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1523624759693821

► Cardiometabolic disease, a condition characterized by an abnormal metabolic phenotype,presents a major public health burden, as it is a chronic condition that affects over 30%… (more)

Subjects/Keywords: Biomedical Research; Health; cardiometabolic disease; metabolic syndrome; tissue characterization; non-invasive; multi-modality; MRI; magnetic resonance; CT; computed tomography

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APA (6^th Edition):

Kumar, V. (2018). Towards Multiorgan Characterization of Cardiometabolic Health and Disease. (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1523624759693821

Chicago Manual of Style (16^th Edition):

Kumar, Vidhya. “Towards Multiorgan Characterization of Cardiometabolic Health and Disease.” 2018. Doctoral Dissertation, The Ohio State University. Accessed December 07, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1523624759693821.

MLA Handbook (7^th Edition):

Kumar, Vidhya. “Towards Multiorgan Characterization of Cardiometabolic Health and Disease.” 2018. Web. 07 Dec 2019.

Vancouver:

Kumar V. Towards Multiorgan Characterization of Cardiometabolic Health and Disease. [Internet] [Doctoral dissertation]. The Ohio State University; 2018. [cited 2019 Dec 07]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1523624759693821.

Council of Science Editors:

Kumar V. Towards Multiorgan Characterization of Cardiometabolic Health and Disease. [Doctoral Dissertation]. The Ohio State University; 2018. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1523624759693821

23. Hanoune, Souheïl. Vers un modèle plausible de sélection de l'action pour un robot mobile : Toward a plausible model of action selection for a mobile robot.

Degree: Docteur es, STIC (sciences et technologies de l'information et de la communication) - Cergy, 2015, Cergy-Pontoise

URL: http://www.theses.fr/2015CERG0758

►

Cette thèse étudie les mécanismes de sélection de l'action et de choix de stratégie tels qu'ils apparaissent à travers des expériences animales et des enregistrements… (more)

▼

Cette thèse étudie les mécanismes de sélection de l'action et de choix de stratégie tels qu'ils apparaissent à travers des expériences animales et des enregistrements neurobiologiques. Nous proposons ensuite des modèles biologiquement plausibles de la sélection de l'action. L'objectif est de mieux comprendre le fonctionnement du cerveau chez les êtres vivants et de pouvoir endéduire des architectures de contrôle bio-inspirées, plus robustes et adaptées à l'environnement. Les modèles étudiés sont réalisés avec des réseaux de neurones artificiels, permettant de modéliser des régions cérébrales et ainsi pouvoir simuler le fonctionnement du cerveau, ce qui permet de tester nos hypothèses sur des robots et des agents virtuels.L'étude de la sélection de l'action pour des robots mobiles implique plusieurs approches. La sélection de l'action peut être étudiée du point de vue du choix entre plusieurs actions basiques, e.g. un choix binaire aller à gauche ou à droite. Ceci passe forcément par l'acquisition et la catégorisation d'instants et d'événements spéciaux, perçus ou effectués, qui représentent des contextes dans lesquels la perception change, le comportement est modifié ou bien la sélection est réalisée. Ainsi, la thèse traite aussi de l'acquisition, la catégorisation et l'encodage de ces événements importants dans la sélection del'action.Enfin, on s'intéressera à la sélection de l'action du point de vue de la sélection de stratégie. Les différents comportements peuvent être dirigés consciemment ou bien être des automatismes acquis avec l'habitude. Le but ici est d'explorer différentes approches pour que le robot puisse développer ces deux capacités, mais aussi d'étudier les interactions entre ces types de mécanismes dans la cadre de tâches de navigation.Les travaux de cette thèse se basent sur la modélisation du fonctionnement de différentes boucles hippocampo-cortico-basales impliquées dans des tâches de navigation, de sélection de l'action et de catégorisations multimodales. En particulier, nous avons un modèle de l'hippocampe permettant d'apprendre des associations spatio-temporelles et des conditionnements multimodaux entre des événements perceptifs. Il se base sur des associations sensorimotrices entre des cellules appelées cellules de lieu qui sont associées avec des actions pour définir des comportements cohérents. Le modèle fait aussi intervenir des cellules de transition hippocampiques, permettant de faire des prédictions temporelles sur les événements futurs. Celles-ci permettent l'apprentissagede séquences spatio-temporelles, notamment du fait qu'elles représentent le substrat neuronal à l'apprentissage d'une carte cognitive, située elle au niveau du cortex préfrontal et/ou pariétal.Ce type de carte permet de planifier des chemins à suivre en fonction des motivations du robot, ce qui permet de rejoindre différents buts précédemment découverts dans l'environnement.

This thesis aims at studying the different mechanisms involved in action selection and decision making processes, according to animal…

Advisors/Committee Members: Quoy, Mathias (thesis director).

Subjects/Keywords: Robotique mobile; Neuroscience; Apprentissage; Réseaux de neurones; Selection de l'action; Multimodalité; Mobile robots; Neuroscience; Learning; Neural Networks; Action selection; Multi-Modality

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APA (6^th Edition):

Hanoune, S. (2015). Vers un modèle plausible de sélection de l'action pour un robot mobile : Toward a plausible model of action selection for a mobile robot. (Doctoral Dissertation). Cergy-Pontoise. Retrieved from http://www.theses.fr/2015CERG0758

Chicago Manual of Style (16^th Edition):

Hanoune, Souheïl. “Vers un modèle plausible de sélection de l'action pour un robot mobile : Toward a plausible model of action selection for a mobile robot.” 2015. Doctoral Dissertation, Cergy-Pontoise. Accessed December 07, 2019. http://www.theses.fr/2015CERG0758.

MLA Handbook (7^th Edition):

Hanoune, Souheïl. “Vers un modèle plausible de sélection de l'action pour un robot mobile : Toward a plausible model of action selection for a mobile robot.” 2015. Web. 07 Dec 2019.

Vancouver:

Hanoune S. Vers un modèle plausible de sélection de l'action pour un robot mobile : Toward a plausible model of action selection for a mobile robot. [Internet] [Doctoral dissertation]. Cergy-Pontoise; 2015. [cited 2019 Dec 07]. Available from: http://www.theses.fr/2015CERG0758.

Council of Science Editors:

Hanoune S. Vers un modèle plausible de sélection de l'action pour un robot mobile : Toward a plausible model of action selection for a mobile robot. [Doctoral Dissertation]. Cergy-Pontoise; 2015. Available from: http://www.theses.fr/2015CERG0758

University of Michigan

24. Green, Crystal. Automated Deformable Mapping Methods to Relate Corresponding Lesions in 3D X-ray and 3D Ultrasound Breast Images.

Degree: PhD, Nuclear Engineering & Radiological Sciences, 2019, University of Michigan

URL: http://hdl.handle.net/2027.42/150042

► Mammography is the current standard imaging method for detecting breast cancer by using x-rays to produce 2D images of the breast. However, with mammography alone… (more)

▼ Mammography is the current standard imaging method for detecting breast cancer by using x-rays to produce 2D images of the breast. However, with mammography alone there is difficulty determining whether a lesion is benign or malignant and reduced sensitivity to detecting lesions in dense breasts. Ultrasound imaging used in conjunction with mammography has shown valuable contributions for lesion characterization by differentiating between solid and cystic lesions. Conventional breast ultrasound has high false positive rates; however, it has shown improved abilities to detect lesions in dense breasts. Breast ultrasound is typically performed freehand to produce anterior-to-posterior 2D images in a different geometry (supine) than mammography (upright). This difference in geometries is likely responsible for the finding that at least 10% of the time lesions found in the ultrasound images do not correspond with lesions found in mammograms. To solve this problem additional imaging techniques must be investigated to aid a radiologist in identifying corresponding lesions in the two modalities to ensure early detection of a potential cancer. This dissertation describes and validates automated deformable mapping methods to register and relate corresponding lesions between multi-modality images acquired using 3D mammography (Digital Breast Tomosynthesis (DBT) and dedicated breast Computed Tomography (bCT)) and 3D ultrasound (Automated Breast Ultrasound (ABUS)). The methodology involves the use of finite element modeling and analysis to simulate the differences in compression and breast orientation to better align lesions acquired from images from these modalities. Preliminary studies were performed using several multimodality compressible breast phantoms to determine breast lesion registrations between: i) cranio-caudal (CC) and mediolateral oblique (MLO) DBT views and ABUS, ii) simulated bCT and DBT (CC and MLO views), and iii) simulated bCT and ABUS. Distances between the centers of masses, dCOM, of corresponding lesions were used to assess the deformable mapping method. These phantom studies showed the potential to apply this technique for real breast lesions with mean dCOM registration values as low as 4.9 ± 2.4 mm for DBT (CC view) mapped to ABUS, 9.3 ± 2.8 mm for DBT (MLO view) mapped to ABUS, 4.8 ± 2.4 mm for bCT mapped to ABUS, 5.0 ± 2.2 mm for bCT mapped to DBT (CC view), and 4.7 ± 2.5 mm for bCT mapped to DBT (MLO view). All of the phantom studies showed that using external fiducial markers helped improve the registration capability of the deformable mapping algorithm. An IRB-approved proof-of-concept study was performed with patient volunteers to validate the deformable registration method on 5 patient datasets with a total of up to 7 lesions for DBT (CC and MLO views) to ABUS registration. Resulting dCOM’s using the deformable method showed statistically significant improvements over rigid registration techniques with a mean dCOM of 11.6 ± 5.3 mm for DBT (CC view) mapped to ABUS and a mean dCOM of 12.3 ± 4.8 mm… Advisors/Committee Members: Bielajew, Alex F (committee member), Goodsitt, Mitchell M (committee member), Carson, Paul L (committee member), Brock, Kristy K (committee member), Matuszak, Martha M (committee member).

Subjects/Keywords: deformable registration; multi-modality breast imaging; biomechanical modeling; digital breast tomosynthesis; automated breast ultrasound; Nuclear Engineering and Radiological Sciences; Engineering

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APA (6^th Edition):

Green, C. (2019). Automated Deformable Mapping Methods to Relate Corresponding Lesions in 3D X-ray and 3D Ultrasound Breast Images. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/150042

Chicago Manual of Style (16^th Edition):

Green, Crystal. “Automated Deformable Mapping Methods to Relate Corresponding Lesions in 3D X-ray and 3D Ultrasound Breast Images.” 2019. Doctoral Dissertation, University of Michigan. Accessed December 07, 2019. http://hdl.handle.net/2027.42/150042.

MLA Handbook (7^th Edition):

Green, Crystal. “Automated Deformable Mapping Methods to Relate Corresponding Lesions in 3D X-ray and 3D Ultrasound Breast Images.” 2019. Web. 07 Dec 2019.

Vancouver:

Green C. Automated Deformable Mapping Methods to Relate Corresponding Lesions in 3D X-ray and 3D Ultrasound Breast Images. [Internet] [Doctoral dissertation]. University of Michigan; 2019. [cited 2019 Dec 07]. Available from: http://hdl.handle.net/2027.42/150042.

Council of Science Editors:

Green C. Automated Deformable Mapping Methods to Relate Corresponding Lesions in 3D X-ray and 3D Ultrasound Breast Images. [Doctoral Dissertation]. University of Michigan; 2019. Available from: http://hdl.handle.net/2027.42/150042

25. Postma, Barteld. Serious auralizations : Auralisations sérieuses.

Degree: Docteur es, Informatique, 2017, Paris Saclay

URL: http://www.theses.fr/2017SACLS091

► Au cours des dernières décennies, la présence des auralisations dans l’acoustique architecturale et la réalité virtuelle est devenue de plus en plus importante. De nombreuses… (more)

▼ Au cours des dernières décennies, la présence des auralisations dans l’acoustique architecturale et la réalité virtuelle est devenue de plus en plus importante. De nombreuses applications en découlent, telles que les explorations de la réalité virtuelle multimodale ou les études de l’influence acoustique des rénovations et la recherche historique. Malgré ces nombreux cas d’utilisation, peu d’études scientifiques ont été réalisées sur le sujet. L’objectif de cette thèse était donc d’examiner l’utilisation d’auralisations acoustiques de salles, basées sur l’acoustique géométrique (GA) comme outil scientifique et visant à aider à la création d’auralisations historiquement exactes plus écologiquement valables. Déjà dans les années 1930 les premières tentatives ont été entreprises pour rendre audible (de manière imaginaire) les champs sonores. Les développements au cours des 80 dernières années ont conduit à des améliorations significatives des auralisations. Aujourd’hui, si l’on veut créer des auralisations, l’enregistrement anéchoïque réalisé préalablement doit être convolué avec une réponse impulsionnelle ambiante, mesurée ou simulée (RIR). Les logiciels GA sont souvent utilisés pour calculer numériquement la RIR de géométries compliquées. Les méthodes basées sur les ondes sont gourmandes en calcul, nécessitant des modèles géométriques complexes et des données d’entrée complexes. Cette thèse vise à améliorer la qualité des auralisations entièrement calculées. À cette fin, on a étudié l’étalonnage des modèles acoustiques des salles et l’inclusion de la directivité vocale dynamique. Des mesures acoustiques de la pièce ont été réalisées dans quatre salles et des modèles d’acoustique géométrique ont été créés des mêmes espaces. Une procédure méthodique de calibration du modèle a été proposée, réalisée dans les quatre salles, et validée au préalable par comparaison d’estimation de paramètres. Des tests d’écoute subjectifs comparant des auralisations mesurée set simulées pour trois espaces différents ont révélé que les auralisations étaient également perçues pour huit attributs acoustiques évalués. Par la suite, un cadre permettant d’inclure la directivité vocale dynamique a été présenté. Les résultats des tests d’écoute ont montré des différences perceptuelles entre la directivité vocale dynamique et la directivité de source statique pour la plausibilité, l’enveloppement de l’auralisation ainsi que la largeur perçue de la source. L’amélioration de la validité écologique des auralisations a permis d’étudier l’influence des visualisations sur l’expérience acoustique, avec un degré de confiance raisonnable que les effets perçus sont également applicables dans des situations réelles. À cet effet, un cadre a été établi qui a permis des évaluations multimodales de pièces de théâtre et de concerts. Les résultats d’un test d’écoute multi-modal présentant une scène cohérente visuelle-sonore ont confirmé les différences perceptuelles entre les auralisations de directivité vocale dynamique et statique. Dans ce même cadre, un second… Advisors/Committee Members: Katz, Brian F.G. (thesis director).

Subjects/Keywords: Réalité virtuelle; Auralisations; Visualisations; Acoustique archéologique; Calibration; Direction de la voix; Multi-modalité; Virtual reality; Auralizations; Visualizations; Archaeological acoustics; Calibration; Voice directivity; Multi-modality

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APA (6^th Edition):

Postma, B. (2017). Serious auralizations : Auralisations sérieuses. (Doctoral Dissertation). Paris Saclay. Retrieved from http://www.theses.fr/2017SACLS091

Chicago Manual of Style (16^th Edition):

Postma, Barteld. “Serious auralizations : Auralisations sérieuses.” 2017. Doctoral Dissertation, Paris Saclay. Accessed December 07, 2019. http://www.theses.fr/2017SACLS091.

MLA Handbook (7^th Edition):

Postma, Barteld. “Serious auralizations : Auralisations sérieuses.” 2017. Web. 07 Dec 2019.

Vancouver:

Postma B. Serious auralizations : Auralisations sérieuses. [Internet] [Doctoral dissertation]. Paris Saclay; 2017. [cited 2019 Dec 07]. Available from: http://www.theses.fr/2017SACLS091.

Council of Science Editors:

Postma B. Serious auralizations : Auralisations sérieuses. [Doctoral Dissertation]. Paris Saclay; 2017. Available from: http://www.theses.fr/2017SACLS091

Brno University of Technology

26. Hanák, Jaroslav. Aplikace pro demonstraci multi-biometrické fúze .

Degree: 2014, Brno University of Technology

URL: http://hdl.handle.net/11012/56414

► Tato práce je zaměřena na oblast biometrie, multi-biometrie, normalizace a fúze v multi-biometrických systémech a jejich hodnocení výkonnosti. Obsahuje stručný úvod do této problematiky a… (more)

Subjects/Keywords: Biometrie; multi-biometrie; fúze; normalizace; Qt; FMR; FNMR; EER; aplikace; modality; výkonnost; DET; hustota pravděpodobnosti.; Biometric; multi-biometric; fusion; normalization; Qt; FMR; FNMR; EER; application; modalities; performance; DET; probability density.

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hanák, J. (2014). Aplikace pro demonstraci multi-biometrické fúze . (Thesis). Brno University of Technology. Retrieved from http://hdl.handle.net/11012/56414

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Hanák, Jaroslav. “Aplikace pro demonstraci multi-biometrické fúze .” 2014. Thesis, Brno University of Technology. Accessed December 07, 2019. http://hdl.handle.net/11012/56414.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Hanák, Jaroslav. “Aplikace pro demonstraci multi-biometrické fúze .” 2014. Web. 07 Dec 2019.

Vancouver:

Hanák J. Aplikace pro demonstraci multi-biometrické fúze . [Internet] [Thesis]. Brno University of Technology; 2014. [cited 2019 Dec 07]. Available from: http://hdl.handle.net/11012/56414.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Hanák J. Aplikace pro demonstraci multi-biometrické fúze . [Thesis]. Brno University of Technology; 2014. Available from: http://hdl.handle.net/11012/56414

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

27. Wang, Hening. Development of multi-modality polymer-coated quantum dots for cancer imaging.

Degree: PhD, Biomedical Engineering (Joint GT/Emory Department), 2016, Georgia Tech

URL: http://hdl.handle.net/1853/55611

► Cancer has become a large threat to people’s health and lives in the world. It is very important if we can achieve the early diagnosis… (more)

Subjects/Keywords: Quantum dots; Multi-modality; Cancer imaging; Hyaluronic Acid

…x5D; 52 Figure 4.2: Multi-modality imaging machines. (A) Quad-modality imaging… …TEM figure of HA-DOTA Cu QDs to show a size distribution 88 Figure 5.1: Multi-modality… …imaging probe based on our HA-cystamine QDs system 92 Figure 5.2: Multi-modality imaging probe… …DOTA). These multi-modality imaging probes provide the ability for fluorescence imaging… …require multiple imaging modalities bind to a single probe, a multi-modality imaging probe has…

11 more images…

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Wang, H. (2016). Development of multi-modality polymer-coated quantum dots for cancer imaging. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/55611

Chicago Manual of Style (16^th Edition):

Wang, Hening. “Development of multi-modality polymer-coated quantum dots for cancer imaging.” 2016. Doctoral Dissertation, Georgia Tech. Accessed December 07, 2019. http://hdl.handle.net/1853/55611.

MLA Handbook (7^th Edition):

Wang, Hening. “Development of multi-modality polymer-coated quantum dots for cancer imaging.” 2016. Web. 07 Dec 2019.

Vancouver:

Wang H. Development of multi-modality polymer-coated quantum dots for cancer imaging. [Internet] [Doctoral dissertation]. Georgia Tech; 2016. [cited 2019 Dec 07]. Available from: http://hdl.handle.net/1853/55611.

Council of Science Editors:

Wang H. Development of multi-modality polymer-coated quantum dots for cancer imaging. [Doctoral Dissertation]. Georgia Tech; 2016. Available from: http://hdl.handle.net/1853/55611

28. CHAO XIONG. TOWARDS MULTI-MODAL FACE RECOGNITION IN THE WILD.

Degree: 2015, National University of Singapore

URL: http://scholarbank.nus.edu.sg/handle/10635/135179

Subjects/Keywords: Face Recognition; Face Verification; Multi-Modality; Deep Learning; Random Forest; Feature Learning

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

XIONG, C. (2015). TOWARDS MULTI-MODAL FACE RECOGNITION IN THE WILD. (Thesis). National University of Singapore. Retrieved from http://scholarbank.nus.edu.sg/handle/10635/135179

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

XIONG, CHAO. “TOWARDS MULTI-MODAL FACE RECOGNITION IN THE WILD.” 2015. Thesis, National University of Singapore. Accessed December 07, 2019. http://scholarbank.nus.edu.sg/handle/10635/135179.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

XIONG, CHAO. “TOWARDS MULTI-MODAL FACE RECOGNITION IN THE WILD.” 2015. Web. 07 Dec 2019.

Vancouver:

XIONG C. TOWARDS MULTI-MODAL FACE RECOGNITION IN THE WILD. [Internet] [Thesis]. National University of Singapore; 2015. [cited 2019 Dec 07]. Available from: http://scholarbank.nus.edu.sg/handle/10635/135179.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

XIONG C. TOWARDS MULTI-MODAL FACE RECOGNITION IN THE WILD. [Thesis]. National University of Singapore; 2015. Available from: http://scholarbank.nus.edu.sg/handle/10635/135179

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

29. Gao, Zhenhuan. Omnidirectional view and multi-modal streaming in 3D tele-immersion system.

Degree: MS, Computer Science, 2015, University of Illinois – Urbana-Champaign

URL: http://hdl.handle.net/2142/89071

► 3D Tele-immersion (3DTI) technology allows full-body, multi-modal content delivery among geographically dispersed users. In 3DTI, user’s 3D model will be captured by multiple RGB-D (color… (more)

Subjects/Keywords: 3D; multi-modality; view; Dynamic Adaptive Streaming over HTTP (DASH)

…the complexity of multi-modality, how to manage, store and retrieve multi-modal 3D data in… …3DTI 3DTI systems aim towards multi-purpose, multi-sites, and multi-modality to enable a wide… …Omniviewer 3D DASH system The deployment of OmniViewer recording site . . MPD file and the Multi… …system is currently aiming at multi-purpose, multisites, and multi-modal platform in order to… …including omnidirectional view and multi-modal 3D video streaming. In this chapter, section 1.1…

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APA (6^th Edition):

Gao, Z. (2015). Omnidirectional view and multi-modal streaming in 3D tele-immersion system. (Thesis). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/89071

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Gao, Zhenhuan. “Omnidirectional view and multi-modal streaming in 3D tele-immersion system.” 2015. Thesis, University of Illinois – Urbana-Champaign. Accessed December 07, 2019. http://hdl.handle.net/2142/89071.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Gao, Zhenhuan. “Omnidirectional view and multi-modal streaming in 3D tele-immersion system.” 2015. Web. 07 Dec 2019.

Vancouver:

Gao Z. Omnidirectional view and multi-modal streaming in 3D tele-immersion system. [Internet] [Thesis]. University of Illinois – Urbana-Champaign; 2015. [cited 2019 Dec 07]. Available from: http://hdl.handle.net/2142/89071.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Gao Z. Omnidirectional view and multi-modal streaming in 3D tele-immersion system. [Thesis]. University of Illinois – Urbana-Champaign; 2015. Available from: http://hdl.handle.net/2142/89071

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

30. Swellengrebel, Hendrik Albert Maurits. Challenges in the multimodality treatment of rectal cancer.

Degree: 2013, Department of Clinical Oncology, Faculty of Medicine / Leiden University Medical Center (LUMC), Leiden University

URL: http://hdl.handle.net/1887/22038

► Remaining questions and current goals in the treatment of rectal cancer include optimizing staging accuracy, establishing the optimal neoadjuvant strategy to be implemented in the… (more)

Subjects/Keywords: Cancer; Rectal cancer; Organ sparing; Non-operative strategies; New multi-modality treatments; Cancer; Rectal cancer; Organ sparing; Non-operative strategies; New multi-modality treatments

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Swellengrebel, H. A. M. (2013). Challenges in the multimodality treatment of rectal cancer. (Doctoral Dissertation). Department of Clinical Oncology, Faculty of Medicine / Leiden University Medical Center (LUMC), Leiden University. Retrieved from http://hdl.handle.net/1887/22038

Chicago Manual of Style (16^th Edition):

Swellengrebel, Hendrik Albert Maurits. “Challenges in the multimodality treatment of rectal cancer.” 2013. Doctoral Dissertation, Department of Clinical Oncology, Faculty of Medicine / Leiden University Medical Center (LUMC), Leiden University. Accessed December 07, 2019. http://hdl.handle.net/1887/22038.

MLA Handbook (7^th Edition):

Swellengrebel, Hendrik Albert Maurits. “Challenges in the multimodality treatment of rectal cancer.” 2013. Web. 07 Dec 2019.

Vancouver:

Swellengrebel HAM. Challenges in the multimodality treatment of rectal cancer. [Internet] [Doctoral dissertation]. Department of Clinical Oncology, Faculty of Medicine / Leiden University Medical Center (LUMC), Leiden University; 2013. [cited 2019 Dec 07]. Available from: http://hdl.handle.net/1887/22038.

Council of Science Editors:

Swellengrebel HAM. Challenges in the multimodality treatment of rectal cancer. [Doctoral Dissertation]. Department of Clinical Oncology, Faculty of Medicine / Leiden University Medical Center (LUMC), Leiden University; 2013. Available from: http://hdl.handle.net/1887/22038

Open Access Theses and Dissertations