subject:(Microfluidic flow control system)

University of Pennsylvania

1. Qin, Mian. Microfluidic Pumping With Surface Tension Force and Magnetohydrodynamic Drive.

Degree: 2011, University of Pennsylvania

URL: https://repository.upenn.edu/edissertations/385

► Micropumping is difficult to design and control as compared to their macro-scale counterparts due to the size limitation. The first part of this dissertation focuses… (more)

▼ Micropumping is difficult to design and control as compared to their macro-scale counterparts due to the size limitation. The first part of this dissertation focuses on micropumping with surface tension forces. A simple, single-action, capillary pump/valve consisting of a bi-phase slug confined in a non-uniform conduit is described. At low temperatures, the slug is solid and seals the conduit. Once heated above its melting temperature, the liquid slug moves spontaneously along a predetermined path due to surface tension forces imbalance. This technique can be easily combined with other propulsion mechanisms such as pressure and magnetohydrodynamics (MHD). The second part of this dissertation focuses on MHD micropumping, which provides a convenient, programmable means for propelling liquids and controlling fluid flow without a need for mechanical pumps and valves. Firstly, we examined the response of a model one dimensional electrochemical thin film to time-independent and time-dependent applied polarizations, using the Nernst-Planck (NP) model with electroneutrality and the Poisson-Nernst-Planck (PNP) model without electro -neutrality, respectively. The NP model with well designed boundary conditions was v developed, proved capable of describing the bulk behavior as accurate as the full PNP model. Secondly, we studied the MHD propelled liquid motion in a uniform conduit patterned with cylinders. We proved equivalence in MHD and pressure driven flow patterns under certain conditions. We examined the effect of interior obstacles on the electric current flow in the conduit and showed the existence of particular pillar geometry that maximizes the current. Thirdly, we looked at MHD flow of a binary electrolyte between concentric cylinders. The base flow was similar to the pressure driven flow in the same setup. The first order perturbation fields, however, behave differently as the traditional Dean’s flow. We carried out one-dimensional linear stability analysis for the unbounded small gap situation and solved it as an eigenvalue problem. Two-dimensional nonlinear simulation was performed for finite gap size or bounded situations. We observed strong directionality of the applied electric field for the onset of stability. Results in this study could help enhance the stability of the system or introduce secondary motion depending on the nature of the applications.

Subjects/Keywords: magnetohydrodynamic flow; MHD; microfluidic; electrochemical system; surface tension; electrokinetic flow; Other Mechanical Engineering; Transport Phenomena

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APA (6^th Edition):

Qin, M. (2011). Microfluidic Pumping With Surface Tension Force and Magnetohydrodynamic Drive. (Thesis). University of Pennsylvania. Retrieved from https://repository.upenn.edu/edissertations/385

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Qin, Mian. “Microfluidic Pumping With Surface Tension Force and Magnetohydrodynamic Drive.” 2011. Thesis, University of Pennsylvania. Accessed April 16, 2021. https://repository.upenn.edu/edissertations/385.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Qin, Mian. “Microfluidic Pumping With Surface Tension Force and Magnetohydrodynamic Drive.” 2011. Web. 16 Apr 2021.

Vancouver:

Qin M. Microfluidic Pumping With Surface Tension Force and Magnetohydrodynamic Drive. [Internet] [Thesis]. University of Pennsylvania; 2011. [cited 2021 Apr 16]. Available from: https://repository.upenn.edu/edissertations/385.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Qin M. Microfluidic Pumping With Surface Tension Force and Magnetohydrodynamic Drive. [Thesis]. University of Pennsylvania; 2011. Available from: https://repository.upenn.edu/edissertations/385

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

NSYSU

2. Chen, Chung-hsiang. Novel Cassette-Based Two Dimensional Paper Chromatography Integrated with Electrospray Ionization for Mass Spectrometry Detections.

Degree: Master, Mechanical and Electro-Mechanical Engineering, 2016, NSYSU

URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0820116-055341

► This research successfully presents a lateral flow cassette combined with electrospray ionization (ESI) for rapid mass spectrometry detection of ambient samples. The developed aims to… (more)

▼ This research successfully presents a lateral flow cassette combined with electrospray ionization (ESI) for rapid mass spectrometry detection of ambient samples. The developed aims to substitute conventional food-safety examination approaches such as high performance liquid chromatography tandem mass spectrometer (HPLC/MS) and gas chromatography tandem mass spectrometer (GC/MS). The cassette is demonstrated with the ingredient separation and electrospray process of the ambient liquid samples under unique cassette-based two-dimensional (2-D) paper chromatography scheme. Liquid sample is directly applied on the cassette for sample separation with paper chromatography and then concentrated with the second paper chromatography for enhancing the detection performance of ESI. Results show that the electrospray ion intensity is enhanced for 100 times higher after the 2-D paper chromatography process for sample enrichment. The whole process can be done in 30 min on a patterned filter paper. The time and cost for food-safety examination can be dramatically reduced with the developed method. The experimental results also indicated that the developed cassette exhibits a lower limit of detection (LOD) of 1.0 ppb for detecting acetaminophen and vitamin B2. The intensity for ESI on the paper tips is as high as 1010 ions/ cm3 for the paper tip of 60o. Several samples including like Chinese herbal medicines (cinnamon), raw vegetables (garlic, green onion), clinical medicines (acetaminophen, chlorpheniramine), paraquat-spiked garlic sample are used to evaluate the performance of the developed method. Moreover, two pesticides of pyrimethanil (fungicide) and fluazifop-butyl (herbicides) in raw fresh green onion are detected with high SNR (signal to noise ratio) of 4.77 dB. The developed method has shown its potential on rapid food-safety examination compared to conventional HPLC/MS & GC/MS. Advisors/Committee Members: Cheng-Hsin Chuang (chair), Shin-Pon Ju (chair), Wei-Chih Lin (chair), Lung-Ming Fu (chair), Che-Hsin Lin (committee member).

Subjects/Keywords: Electrospray ionization; Lateral flow system; Paper-based microfluidic; Paper chromatography; Mass spectrometry

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APA (6^th Edition):

Chen, C. (2016). Novel Cassette-Based Two Dimensional Paper Chromatography Integrated with Electrospray Ionization for Mass Spectrometry Detections. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0820116-055341

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Chen, Chung-hsiang. “Novel Cassette-Based Two Dimensional Paper Chromatography Integrated with Electrospray Ionization for Mass Spectrometry Detections.” 2016. Thesis, NSYSU. Accessed April 16, 2021. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0820116-055341.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Chen, Chung-hsiang. “Novel Cassette-Based Two Dimensional Paper Chromatography Integrated with Electrospray Ionization for Mass Spectrometry Detections.” 2016. Web. 16 Apr 2021.

Vancouver:

Chen C. Novel Cassette-Based Two Dimensional Paper Chromatography Integrated with Electrospray Ionization for Mass Spectrometry Detections. [Internet] [Thesis]. NSYSU; 2016. [cited 2021 Apr 16]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0820116-055341.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Chen C. Novel Cassette-Based Two Dimensional Paper Chromatography Integrated with Electrospray Ionization for Mass Spectrometry Detections. [Thesis]. NSYSU; 2016. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0820116-055341

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Cornell University

3. Yu, Yizui. Passive Microfluidic Mixer Fabrication And Flow Test.

Degree: M.S., Applied Physics, Applied Physics, 2012, Cornell University

URL: http://hdl.handle.net/1813/31192

► This study proposed different materials of microfluidic mixer fabrication and their flow test. Two different design based on a T-mixer were fabricated. J-shaped and vertical… (more)

Subjects/Keywords: Microfluidic mixer; fabrication; flow test

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APA (6^th Edition):

Yu, Y. (2012). Passive Microfluidic Mixer Fabrication And Flow Test. (Masters Thesis). Cornell University. Retrieved from http://hdl.handle.net/1813/31192

Chicago Manual of Style (16^th Edition):

Yu, Yizui. “Passive Microfluidic Mixer Fabrication And Flow Test.” 2012. Masters Thesis, Cornell University. Accessed April 16, 2021. http://hdl.handle.net/1813/31192.

MLA Handbook (7^th Edition):

Yu, Yizui. “Passive Microfluidic Mixer Fabrication And Flow Test.” 2012. Web. 16 Apr 2021.

Vancouver:

Yu Y. Passive Microfluidic Mixer Fabrication And Flow Test. [Internet] [Masters thesis]. Cornell University; 2012. [cited 2021 Apr 16]. Available from: http://hdl.handle.net/1813/31192.

Council of Science Editors:

Yu Y. Passive Microfluidic Mixer Fabrication And Flow Test. [Masters Thesis]. Cornell University; 2012. Available from: http://hdl.handle.net/1813/31192

University of British Columbia

4. Bazargan, Vahid. Micro flow control using thermally responsive polymer solutions.

Degree: Master of Applied Science - MASc, Mechanical Engineering, 2008, University of British Columbia

URL: http://hdl.handle.net/2429/2638

► Microfluidics refers to devices and methods for controlling and manipulating fluid flows at length scales less than a millimeter. Miniaturization of a laboratory to a… (more)

Subjects/Keywords: Microfluidic; Pluronic solutions; Microchannel; Micro flow control

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APA (6^th Edition):

Bazargan, V. (2008). Micro flow control using thermally responsive polymer solutions. (Masters Thesis). University of British Columbia. Retrieved from http://hdl.handle.net/2429/2638

Chicago Manual of Style (16^th Edition):

Bazargan, Vahid. “Micro flow control using thermally responsive polymer solutions.” 2008. Masters Thesis, University of British Columbia. Accessed April 16, 2021. http://hdl.handle.net/2429/2638.

MLA Handbook (7^th Edition):

Bazargan, Vahid. “Micro flow control using thermally responsive polymer solutions.” 2008. Web. 16 Apr 2021.

Vancouver:

Bazargan V. Micro flow control using thermally responsive polymer solutions. [Internet] [Masters thesis]. University of British Columbia; 2008. [cited 2021 Apr 16]. Available from: http://hdl.handle.net/2429/2638.

Council of Science Editors:

Bazargan V. Micro flow control using thermally responsive polymer solutions. [Masters Thesis]. University of British Columbia; 2008. Available from: http://hdl.handle.net/2429/2638

University of Michigan

5. Sammarco, Timothy S. A microfluidic thermocapillary pumping system for microfabricated analysis devices.

Degree: PhD, Mechanics, 1999, University of Michigan

URL: http://hdl.handle.net/2027.42/131778

► A non-mechanical pumping mechanism, thermocapillary pumping (TCP), is developed for moving nano-liter sized drops of liquid within integrated microfabricated analysis devices. In TCP, one end… (more)

▼ A non-mechanical pumping mechanism, thermocapillary pumping (TCP), is developed for moving nano-liter sized drops of liquid within integrated microfabricated analysis devices. In TCP, one end of a single drop is heated to create a surface tension difference between the ends of the drop, which causes a capillary pressure difference between the two drop ends and results in drop motion. TCP velocities of up to ~20 mm/min were measured with different liquids at temperature differences between approximately 10 and 70°C, in agreement with theoretical predictions within corresponding uncertainty limits. Several techniques are suggested for assisting TCP when contact angle hysteresis, a resistance opposing TCP, is too large. These techniques include using surface treatments to reduce the contact angle hysteresis, converging channels to offset hysteresis, or an applied pressure to assist in movement. Results are also presented from a finite difference, heat transfer analysis of TCP devices. The analysis incorporates both fluid flow and energy transport through multiple device layers. Factors examined include the choice of channel/substrate material and thickness, pumping velocity, and channel/substrate boundary conditions. Results from a base case design with single-sided heating (fused silica heater substrate, glass channel cap, and water) show that near uniform interface temperatures can be achieved with drop velocities below ~1 cm/s. Extending the analysis to thermal reaction channels heated from bottom side, it was shown that uniform reaction temperatures Were obtained when channel/reactor heights were maintained below ~50 mum. Lastly, an integrated Y-shaped device was designed and fabricated to integrate typical movement, mixing, and reaction operations within a single device. The above integral integrated reaction sequence was performed using a restriction digest reaction (RDR), which a common DNA analysis reaction. By integrating these operations into a single micro microfabricated device using TCP, the successful integration of a common DNA analysis reaction, a restriction digest reaction was demonstrated. Using repetitions of the Y-device case format, more complicated analysis systems, such as one for DNA sequencing, may be fabricated. Advisors/Committee Members: Burns, Mark A. (advisor).

Subjects/Keywords: Analysis; Devices; Flow; Microfabricated; Microfluidic; Pumping; System; Thermocapillary

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APA (6^th Edition):

Sammarco, T. S. (1999). A microfluidic thermocapillary pumping system for microfabricated analysis devices. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/131778

Chicago Manual of Style (16^th Edition):

Sammarco, Timothy S. “A microfluidic thermocapillary pumping system for microfabricated analysis devices.” 1999. Doctoral Dissertation, University of Michigan. Accessed April 16, 2021. http://hdl.handle.net/2027.42/131778.

MLA Handbook (7^th Edition):

Sammarco, Timothy S. “A microfluidic thermocapillary pumping system for microfabricated analysis devices.” 1999. Web. 16 Apr 2021.

Vancouver:

Sammarco TS. A microfluidic thermocapillary pumping system for microfabricated analysis devices. [Internet] [Doctoral dissertation]. University of Michigan; 1999. [cited 2021 Apr 16]. Available from: http://hdl.handle.net/2027.42/131778.

Council of Science Editors:

Sammarco TS. A microfluidic thermocapillary pumping system for microfabricated analysis devices. [Doctoral Dissertation]. University of Michigan; 1999. Available from: http://hdl.handle.net/2027.42/131778

Michigan State University

6. Gross, Bethany. Microfluidic and 3D printing technologies for the development of an in vitro thrombus mimic.

Degree: 2016, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:3989

►

Thesis Ph. D. Michigan State University. Chemistry 2016.

Platelets from individuals with diabetes, cystic fibrosis, multiple sclerosis, hypertension, and sickle cell anemia are hyperactive or… (more)

▼

Thesis Ph. D. Michigan State University. Chemistry 2016.

Platelets from individuals with diabetes, cystic fibrosis, multiple sclerosis, hypertension, and sickle cell anemia are hyperactive or more likely to aggregate and form a blood clot or thrombus. Furthermore, each of these diseases exhibits abnormal red blood cell (RBC) adenosine triphosphate (ATP) release, an agonist of platelet activation. RBC-derived ATP release is also a proven factor in the regulation of vascular tone through a signal cascade that results in nitric oxide release from endothelial cells and relaxation of smooth muscle cells. This relaxation leads to vessel dilation and a localized increase in blood flow. The presence of hyperactive platelets in conjunction with altered RBC-derived ATP release results in an impaired ability to dilate local resistance vessels, and ultimately puts individuals with these diseases at higher risk for deleterious thrombus formation. The work detailed in this dissertation outlines the development of microfluidic and 3D printed in vitro models of in vivo circulation, capable of inducing an injury to a localized region of the endothelium. Specifically, chemical and electrical lysis of endothelial cells will be demonstrated through the use of embedded or removable electrodes or with laser irradiation of a photochemical dye. The fabricated devices mimic flow seen in blood vessels, facilitate the study of platelet adhesion to sub-endothelial collagen, and allow for the study of thrombus formation in stored blood samples showing altered ATP release from RBCs. With a more rapid fabrication process, reusability of the final device, and possibility of standardization via open software sharing, 3D printing offers a more attractive method to develop and utilize an in vitro thrombus mimic compared to more widely employed soft lithographic techniques. Channels of 3D printed devices featured a stenosis region (0.8 mm height, 2 mm length, and 1 mm width) and wide regions (device 1: 5; device 2: 3.83 mm width). Surface modification of channels with either polydimethylsiloxane (PDMS) or polystyrene (PS) was necessary to promote endothelial cell adherence. Thicknesses of PDMS and PS channel coatings were determined using scanning electron microscopy. The PDMS coating varied in thickness from 3 μm to 100 μm. Multiple PS coatings were required to form a 100 μm thick coating. Cells remained viable on the devices for five days (98% viable), though cell coverage decreased after day four with static media delivery. Optimal lysis conditions (applied electrical potential and duration) were determined for the two different geometries of the 3D printed devices to ensure localized endothelial cell clearance. Selective cell lysis was achieved with efficiencies of 94% (device 1) and 96% (device 2). FDA approved blood storage solutions expose RBCs to hyperglycemic amounts of glucose. As seen with RBCs from individuals with diabetes, ATP release from stored RBCs is significantly decreased compared to control RBCs. The effect of this decreased ATP…

Advisors/Committee Members: Spence, Dana, Bruening, Merlin, Blanchard, Gary, Beaulac, Remi.

Subjects/Keywords: Blood flow – Simulation methods; Thrombosis – Simulation methods; Cardiovascular system – Diseases – Simulation methods; Microfluidic devices; Three-dimensional printing; Chemistry; Biomedical engineering

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APA (6^th Edition):

Gross, B. (2016). Microfluidic and 3D printing technologies for the development of an in vitro thrombus mimic. (Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:3989

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Gross, Bethany. “Microfluidic and 3D printing technologies for the development of an in vitro thrombus mimic.” 2016. Thesis, Michigan State University. Accessed April 16, 2021. http://etd.lib.msu.edu/islandora/object/etd:3989.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Gross, Bethany. “Microfluidic and 3D printing technologies for the development of an in vitro thrombus mimic.” 2016. Web. 16 Apr 2021.

Vancouver:

Gross B. Microfluidic and 3D printing technologies for the development of an in vitro thrombus mimic. [Internet] [Thesis]. Michigan State University; 2016. [cited 2021 Apr 16]. Available from: http://etd.lib.msu.edu/islandora/object/etd:3989.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Gross B. Microfluidic and 3D printing technologies for the development of an in vitro thrombus mimic. [Thesis]. Michigan State University; 2016. Available from: http://etd.lib.msu.edu/islandora/object/etd:3989

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Delft University of Technology

7. Rosema, Yann (author). Fault-tolerance in decentralized motorway traffic management.

Degree: 2020, Delft University of Technology

URL: http://resolver.tudelft.nl/uuid:b2f59038-efbb-4adf-a02d-50cdc995e249

►

In the Dutch motorway traffic management (MTM) system used by Rijkswaterstaat, a central system and multiple outstations alongside the road communicate with each other to… (more)

Subjects/Keywords: Multi-Agent System; Traffic control; Flow Control; IOT

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APA (6^th Edition):

Rosema, Y. (. (2020). Fault-tolerance in decentralized motorway traffic management. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:b2f59038-efbb-4adf-a02d-50cdc995e249

Chicago Manual of Style (16^th Edition):

Rosema, Yann (author). “Fault-tolerance in decentralized motorway traffic management.” 2020. Masters Thesis, Delft University of Technology. Accessed April 16, 2021. http://resolver.tudelft.nl/uuid:b2f59038-efbb-4adf-a02d-50cdc995e249.

MLA Handbook (7^th Edition):

Rosema, Yann (author). “Fault-tolerance in decentralized motorway traffic management.” 2020. Web. 16 Apr 2021.

Vancouver:

Rosema Y(. Fault-tolerance in decentralized motorway traffic management. [Internet] [Masters thesis]. Delft University of Technology; 2020. [cited 2021 Apr 16]. Available from: http://resolver.tudelft.nl/uuid:b2f59038-efbb-4adf-a02d-50cdc995e249.

Council of Science Editors:

Rosema Y(. Fault-tolerance in decentralized motorway traffic management. [Masters Thesis]. Delft University of Technology; 2020. Available from: http://resolver.tudelft.nl/uuid:b2f59038-efbb-4adf-a02d-50cdc995e249

University of Alberta

8. Islam, Md Zahurul. Development of an Efficient Quasi-3D Microfluidic Flow Model and Fabrication and Characterization of an All-PDMS Opto-Microfluidic Flow Cytometer.

Degree: PhD, Department of Electrical and Computer Engineering, 2012, University of Alberta

URL: https://era.library.ualberta.ca/files/ms35tb126

► In this thesis, development of a novel microfluidic flow model, and, fabrication and testing of microfluidic cytometer for potential cell detection and sorting applications are… (more)

▼ In this thesis, development of a novel microfluidic flow model, and, fabrication and testing of microfluidic cytometer for potential cell detection and sorting applications are described. The model is formulated by decomposing the flow profile along the height of microfluidic device into a Fourier series that converts the 3D flow equations into a series of coupled 2D equations and is applicable to planar microfluidic devices only. It is validated against the analytical solution for flow in a straight rectangular channel and the full 3D solution of a commercial Navier-Stokes solver for flow in a T-channel. Comparable accuracy to the full 3D numerical solution is achieved by using only three Fourier terms with significant decrease in computation time. The model is also extended to the problems with time-varying boundary conditions. We fabricated two first generation miniaturized cytometer prototypes and used them for preliminary proof-of-concepts experiments. They were built by cutting fluidic channels into two different polymer materials and bonding them between two standard glass slides with epoxy and fusion bonding. We fabricated a second generation of flow cytometer chip consisting of an integrated 2D hydrodynamic focusing system, solid-core optical waveguides and a hydrodynamic side-flow switching system on an all-PDMS platform. Optical propagation losses of the integrated waveguides and signal-to-noise ratio (SNR) of its detection system were characterized. The propagation losses were found to be 1.6 and 1.5 dB/cm for the green and red light, respectively. Detection of fluorescent signal through the waveguide yielded improved SNR than the conventional method of under-chip detection. Fluid flow speeds were estimated from volumetric flow measurements and fluorescent particle tracking experiments and the width of the hydrodynamically focused stream was extracted from microscope flow images. The results were compared to the simulation values obtained from the Q3D model and reasonable agreement was observed. Detection and sorting of microparticles were demonstrated using this device and initial results are presented. The numerical model, the fabrication techniques, and the experimental methods developed in this thesis may be applied to many biomedical engineering applications that use devices utilizing microfluidic flow and optical interrogation.

Subjects/Keywords: Cell sorter; Opto-microfluidic device; Microfluidic modeling; Micro-scale flow

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APA (6^th Edition):

Islam, M. Z. (2012). Development of an Efficient Quasi-3D Microfluidic Flow Model and Fabrication and Characterization of an All-PDMS Opto-Microfluidic Flow Cytometer. (Doctoral Dissertation). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/ms35tb126

Chicago Manual of Style (16^th Edition):

Islam, Md Zahurul. “Development of an Efficient Quasi-3D Microfluidic Flow Model and Fabrication and Characterization of an All-PDMS Opto-Microfluidic Flow Cytometer.” 2012. Doctoral Dissertation, University of Alberta. Accessed April 16, 2021. https://era.library.ualberta.ca/files/ms35tb126.

MLA Handbook (7^th Edition):

Islam, Md Zahurul. “Development of an Efficient Quasi-3D Microfluidic Flow Model and Fabrication and Characterization of an All-PDMS Opto-Microfluidic Flow Cytometer.” 2012. Web. 16 Apr 2021.

Vancouver:

Islam MZ. Development of an Efficient Quasi-3D Microfluidic Flow Model and Fabrication and Characterization of an All-PDMS Opto-Microfluidic Flow Cytometer. [Internet] [Doctoral dissertation]. University of Alberta; 2012. [cited 2021 Apr 16]. Available from: https://era.library.ualberta.ca/files/ms35tb126.

Council of Science Editors:

Islam MZ. Development of an Efficient Quasi-3D Microfluidic Flow Model and Fabrication and Characterization of an All-PDMS Opto-Microfluidic Flow Cytometer. [Doctoral Dissertation]. University of Alberta; 2012. Available from: https://era.library.ualberta.ca/files/ms35tb126

Indian Institute of Science

9. Regmi, Raju. Light Sheet Based Microfluidic Flow Cytometry Techniques for High throughput Interrogation and High-resolution Imaging.

Degree: MSc Engg, Faculty of Engineering, 2018, Indian Institute of Science

URL: http://etd.iisc.ac.in/handle/2005/3108

► Light allows to non-invasively study the complex and dynamic biological phenomenon undergoing within cells and tissues in their native state. The development of super-resolution microscopes… (more)

▼ Light allows to non-invasively study the complex and dynamic biological phenomenon undergoing within cells and tissues in their native state. The development of super-resolution microscopes in recent years has helped to overcome the fundamental limitation imposed by Abbe’s diﬀraction limit, thereby revolutionizing the ﬁeld of molecular and cellular biology. With the advancement of various super-resolution techniques (like STED, PALM, and 4Pi) it is now possible to visualize the nanometeric cellular structures and their dynamics in real time. The limitations of existing ﬂuorescence microscopy techniques are: poor axial resolution when compared to their lateral counterpart, and their inability to produce high resolution images of dynamic samples. This thesis covers two broadly connected areas of ﬂuorescence imaging techniques while addressing these limitations. First, the PSF engineering and spatial ﬁltering technique for axial super-resolution microscopy and second, the integration of light sheet illumination PSF with microﬂuidic cytometry for imaging cells on-the-go. The ﬁrst chapter gives an explicit description on the fundamentals of ﬂuorescence imaging. This introductory chapter includes a variety of optical microscopes, PSF engineering, the resolution limit imposed by the wave nature of light, the photochemistry of the ﬂuorescent dyes, and their proper selection for ﬂuorescence experiments. In addition to the state-of-art imaging techniques, namely Laser Scanning Confocal Microscopy and Light Sheet Microscopy, this chapter also gives a brief explanation on the evolution of imaging cytometry techniques. Their high speed analytic capability (i.e sorting and counting) makes this technique an important tool in health care diagnosis and other various biomedical applications. The chapter ends with a discussion on the operating principle of the ﬂow cytometers and their limitations. The second chapter in this thesis describes the spatial ﬁltering technique for engineering the PSF to eliminate the side-lobes in the system PSF of the 4Pi Confocal Microscopes. Employing an amplitude mask with binary light transmission windows (also called binary ﬁlters), the incident light is structured to minimize the secondary lobes. These lobes are responsible for exciting the oﬀ-focal planes in the specimen, hence provide incorrect map of the ﬂuorophore distribution in the object. The elimination of the side-lobes is essential for the artifact-free axial super-resolution microscopy. This second chapter describes the spatial ﬁltering technique in details (its mathematical formulation, application in ﬂuorescence microscopy for generation of desired PSF including Bessellike beam). Speciﬁcally, spatial ﬁltering technique is employed in 4Pi type-C Confocal Microscope. The spatial mask used results in the reduction of the side-lobes in 1PE case while they are nearly eliminated in 2PE variant of the proposed technique. The side-lobes are reduced by 46% and 76% for 1PE and 2PE when compared to the existing 4Pi type-C Confocal Microscope… Advisors/Committee Members: Mondal, Partha Pratim (advisor).

Subjects/Keywords: Cytometry Techniques; Fluorescence Phenomenon; Optical Microscopy; Fluorescence Imaging Techniques; Microfluidic Flow Cytometry; Imaging Flow Cytometry; Imaging Cytometry System; Spatial Filtering; High Resolution Imaging; Point Spread Function (PSF); Instrumentation

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APA (6^th Edition):

Regmi, R. (2018). Light Sheet Based Microfluidic Flow Cytometry Techniques for High throughput Interrogation and High-resolution Imaging. (Masters Thesis). Indian Institute of Science. Retrieved from http://etd.iisc.ac.in/handle/2005/3108

Chicago Manual of Style (16^th Edition):

Regmi, Raju. “Light Sheet Based Microfluidic Flow Cytometry Techniques for High throughput Interrogation and High-resolution Imaging.” 2018. Masters Thesis, Indian Institute of Science. Accessed April 16, 2021. http://etd.iisc.ac.in/handle/2005/3108.

MLA Handbook (7^th Edition):

Regmi, Raju. “Light Sheet Based Microfluidic Flow Cytometry Techniques for High throughput Interrogation and High-resolution Imaging.” 2018. Web. 16 Apr 2021.

Vancouver:

Regmi R. Light Sheet Based Microfluidic Flow Cytometry Techniques for High throughput Interrogation and High-resolution Imaging. [Internet] [Masters thesis]. Indian Institute of Science; 2018. [cited 2021 Apr 16]. Available from: http://etd.iisc.ac.in/handle/2005/3108.

Council of Science Editors:

Regmi R. Light Sheet Based Microfluidic Flow Cytometry Techniques for High throughput Interrogation and High-resolution Imaging. [Masters Thesis]. Indian Institute of Science; 2018. Available from: http://etd.iisc.ac.in/handle/2005/3108

University of Toronto

10. Motagamwala, Ali Hussain. A Microfluidic, Extensional Flow Device for Manipulating Soft Particles.

Degree: 2013, University of Toronto

URL: http://hdl.handle.net/1807/43263

►

A computer-controlled microfluidic extensional flow device is developed for trapping and manipulating micron-sized hard and soft particles. The extensional flow is generated in a diamond-shaped… (more)

Subjects/Keywords: Microfluidic; particle trapping; extensional flow; tentiometry; 0542

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APA (6^th Edition):

Motagamwala, A. H. (2013). A Microfluidic, Extensional Flow Device for Manipulating Soft Particles. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/43263

Chicago Manual of Style (16^th Edition):

Motagamwala, Ali Hussain. “A Microfluidic, Extensional Flow Device for Manipulating Soft Particles.” 2013. Masters Thesis, University of Toronto. Accessed April 16, 2021. http://hdl.handle.net/1807/43263.

MLA Handbook (7^th Edition):

Motagamwala, Ali Hussain. “A Microfluidic, Extensional Flow Device for Manipulating Soft Particles.” 2013. Web. 16 Apr 2021.

Vancouver:

Motagamwala AH. A Microfluidic, Extensional Flow Device for Manipulating Soft Particles. [Internet] [Masters thesis]. University of Toronto; 2013. [cited 2021 Apr 16]. Available from: http://hdl.handle.net/1807/43263.

Council of Science Editors:

Motagamwala AH. A Microfluidic, Extensional Flow Device for Manipulating Soft Particles. [Masters Thesis]. University of Toronto; 2013. Available from: http://hdl.handle.net/1807/43263

University of Connecticut

11. Ghaisas, Neha A. Understanding Formation and Transport of Amorphous Iron Oxyhydroxides in Porous Media using Microfluidic Flow Cells- a Novel Method to Study Freshwater Iron Cycling.

Degree: MS, Environmental Engineering, 2011, University of Connecticut

URL: https://opencommons.uconn.edu/gs_theses/170

► The ground water and surface water interface (GSI or Hyporheic zone) is a spatially- and temporally-fluctuating biogeochemical transition zone connecting these two distinct hydrological… (more)

▼ The ground water and surface water interface (GSI or Hyporheic zone) is a spatially- and temporally-fluctuating biogeochemical transition zone connecting these two distinct hydrological components. The mixing zone is characterized by a near neutral pH, ambient temperature and a sharp oxygen concentration which in turn has deep impact on the iron cycling and thus the fate of contaminants in the water column. We constructed an experimental micromodel that to observe key processes that affect biogeochemical iron cycling in the fresh water interface zones where the oxic surface water mixes with Fe (II) rich underlying ground water. The flow cell was constructed from Polydimethylsiloxane, (PDMS) a transparent, biologically inert silicone polymer which can be modified to represent the surface properties of natural porous media by oxygen plasma exposure. Our results demonstrated that with 25 seconds of high RF oxygen plasma exposure, the zeta potential of the PDMS surface is well within the reported range for other silicates and can be used as a surrogate for natural porous media. Using preformed iron oxide particles, a particle deposition rate of 415 min^-1 and a single collector efficiency of 0.081 were obtained after PDMS “beads” had reached steady state coating. Iron oxide coating thicknesses on the PDMS beads were greatest at the inlet side of the flow cell and decreased in the flow direction toward the outlet. Reverse chemical gradients of dissolved Fe (II) and oxygen were created in a flow cell using a diffusive mixer to deliver source waters containing iron-only or oxygen-only solutions at circum-neutral pH. Subsequent monitoring of iron oxidation in the flow cell showed iron oxide particles to form and accumulate along the longitudinal center-line of the flow cell where the theoretical Fe (II) oxidation rate was calculated to be highest. Iron oxide particle accumulation in the flow cell was greatest around beads located at the inlet and decreased with distance along the flow path towards the outlet. These results indicate that PDMS micro-models may be used to simulate mixing zones in porous media, in particular the mixing of oxygen-rich water with anoxic iron- or metal-rich groundwater that represents an important aspect of biogeochemical iron cycling in the groundwater-surface water interface. Advisors/Committee Members: Leslie M. Shor;Joseph T. Bushey, Allison A. MacKay.

Subjects/Keywords: Microfluidic Flow Cells; Hyporheic Zone; adsorption; HFO

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APA (6^th Edition):

Ghaisas, N. A. (2011). Understanding Formation and Transport of Amorphous Iron Oxyhydroxides in Porous Media using Microfluidic Flow Cells- a Novel Method to Study Freshwater Iron Cycling. (Masters Thesis). University of Connecticut. Retrieved from https://opencommons.uconn.edu/gs_theses/170

Chicago Manual of Style (16^th Edition):

Ghaisas, Neha A. “Understanding Formation and Transport of Amorphous Iron Oxyhydroxides in Porous Media using Microfluidic Flow Cells- a Novel Method to Study Freshwater Iron Cycling.” 2011. Masters Thesis, University of Connecticut. Accessed April 16, 2021. https://opencommons.uconn.edu/gs_theses/170.

MLA Handbook (7^th Edition):

Ghaisas, Neha A. “Understanding Formation and Transport of Amorphous Iron Oxyhydroxides in Porous Media using Microfluidic Flow Cells- a Novel Method to Study Freshwater Iron Cycling.” 2011. Web. 16 Apr 2021.

Vancouver:

Ghaisas NA. Understanding Formation and Transport of Amorphous Iron Oxyhydroxides in Porous Media using Microfluidic Flow Cells- a Novel Method to Study Freshwater Iron Cycling. [Internet] [Masters thesis]. University of Connecticut; 2011. [cited 2021 Apr 16]. Available from: https://opencommons.uconn.edu/gs_theses/170.

Council of Science Editors:

Ghaisas NA. Understanding Formation and Transport of Amorphous Iron Oxyhydroxides in Porous Media using Microfluidic Flow Cells- a Novel Method to Study Freshwater Iron Cycling. [Masters Thesis]. University of Connecticut; 2011. Available from: https://opencommons.uconn.edu/gs_theses/170

University of Illinois – Urbana-Champaign

12. Thorson, Michael R. Using microscale flow cells to study the electrochemical reduction of carbon dioxide.

Degree: PhD, 0300, 2012, University of Illinois – Urbana-Champaign

URL: http://hdl.handle.net/2142/34541

► An electrochemical process to reduce CO2 has potential to store electrical energy from renewable sources such as wind and solar in chemical form via the… (more)

▼ An electrochemical process to reduce CO2 has potential to store electrical energy from renewable sources such as wind and solar in chemical form via the production of chemical fuels and feedstocks. When combined with a “green” renewable source, this technology provides a means of (a) reducing dependence on foreign oil via enhancing the penetration of renewable technologies into the transportation sector and (b) reducing CO2 emissions by moving away from fossil fuels (Chapter 1). The goal of this research is to use a microfluidic platform to study the influence of electrolytes, reactor conditions and catalysts to address the three primary challenges for the electrochemical reduction of CO2 to CO: (1) low reaction energetic efficiency; (2) low reaction rate; and (3) poor reaction selectivity. This dissertation reports an investigation of roles electrolytes, operating conditions, and catalysts can play in the reduction of CO2. The anion and cation size, along with pH, were found to drastically influence both the current density and selectivity of the product distribution (Chapter 2). Specifically, small anions and large cations were found to favor the production of CO and hinder the evolution of H2. The microfluidic reactor was used to look at the performance of a larger cation, EMIM BF4, an ionic liquid. With the ionic liquid-based electrolyte, an early cathode onset potential was observed at the expense of poor anode performance. The poor anode performance was overcome via the addition of a secondary electrolyte stream. Using the modified reactor, in the presence of an EMIM BF4 electrolyte solution, CO production was achieved at a reactor potential of only 1.5 V, which constitutes a maximum cathode overpotential of 0.17 V (Chapter 3). This low onset potential constitutes a drastic reduction in the onset potential for CO production in an arrangement that achieves excellent selectivity for CO. While the energetic efficiency in the dual electrolyte setup was drastically improved, the achieved current density was quite low because the EMIM+ cation poisoned the cathode. Because the poor anode performance was from the BF4 anion, the membrane could be eliminated by substituting a BF4 anion in the ionic liquid electrolyte solution for either a OH or Cl anion. The substitution of the BF4 anion for either a OH or Cl anion enabled drastic improvements in the partial current density for CO when using either an EMIM OH or an EMIM Cl electrolyte solution (Chapter 4). Further improvements were achieved via bolstering the conductivity with the addition of a secondary salt, KOH. Amine-based novel organometallic complexes have been developed for the electrochemical reduction of CO2 to CO (Chapter 5). Specifically, several silver-based organometallic catalysts, AgDAT, AgPc, and AgPz, have comparable or better current densities with increased selectivity for CO as compared to Ag nanoparticle-based catalysts. Furthermore, when comparing the performance relative to the silver loading, the amine-based organometallic… Advisors/Committee Members: Kenis, Paul J.A. (advisor), Kenis, Paul J.A. (Committee Chair), Zukoski, Charles F. (committee member), Schroeder, Charles M. (committee member), Gewirth, Andrew A. (committee member), Rauchfuss, Thomas B. (committee member).

Subjects/Keywords: Microfluidic; Electrochemistry; Carbon Dioxide Conversion; Flow Reactor

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APA (6^th Edition):

Thorson, M. R. (2012). Using microscale flow cells to study the electrochemical reduction of carbon dioxide. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/34541

Chicago Manual of Style (16^th Edition):

Thorson, Michael R. “Using microscale flow cells to study the electrochemical reduction of carbon dioxide.” 2012. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed April 16, 2021. http://hdl.handle.net/2142/34541.

MLA Handbook (7^th Edition):

Thorson, Michael R. “Using microscale flow cells to study the electrochemical reduction of carbon dioxide.” 2012. Web. 16 Apr 2021.

Vancouver:

Thorson MR. Using microscale flow cells to study the electrochemical reduction of carbon dioxide. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2012. [cited 2021 Apr 16]. Available from: http://hdl.handle.net/2142/34541.

Council of Science Editors:

Thorson MR. Using microscale flow cells to study the electrochemical reduction of carbon dioxide. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2012. Available from: http://hdl.handle.net/2142/34541

13. Varon, Eliott. Contrôle réactif d'écoulements décollés à l'aide de PIV temps réel : Closed-loop control separated flows using real-time PIV.

Degree: Docteur es, Mécanique, 2017, Paris Sciences et Lettres (ComUE)

URL: http://www.theses.fr/2017PSLET008

►

Les écoulements décollés sont omniprésents dans la nature comme dans les écoulements industriels (aérodynamique externe des véhicules, des bâtiments, écoulements autour d’aubes de turbines, aérodynamique… (more)

▼

Les écoulements décollés sont omniprésents dans la nature comme dans les écoulements industriels (aérodynamique externe des véhicules, des bâtiments, écoulements autour d’aubes de turbines, aérodynamique interne dans des tuyaux...) où ils sont en général sources de nuisances (vibrations, bruit aéroacousitque, forces de traînée ou de portance). Les enjeux associés à la compréhension et à la maîtrise de tels écoulements, caractérisés par une bulle de recirculation, sont donc considérables.Un capteur "visuel" non invasif développé au laboratoire PMMH est d'abord amélioré afin d'accéder en temps réel aux champs de vitesses - et à leurs grandeurs dérivées - des écoulements rencontrés en soufflerie industrielle. Basé sur un algorithme de flot optique issu de la vision par ordinateur, cette approche expérimentale novatrice permet de faciliter les études paramétriques et peut être implémenté dans des boucles de contrôle réactif.Ensuite, les mesures obtenues pour un écoulement sur une plaque plane sont analysées dans le cadre de l'identification de système. Un modèle d’ordre réduit est alors construit par apprentissage, permettant de prédire la dynamique de la transition de la couche limite laminaire vers la turbulence.Enfin, le sillage pleinement turbulent derrière une géométrie modélisant une voiture simplifiée est caractérisé, de façon classique et en tant que système dynamique. Différentes modifications de l'écoulement à l'aide de micro-jets sont testées. Une loi de contrôle réactif consistant à suivre et forcer la recirculation est mise en œuvre avec succès.

Separated flows are ubiquitous in nature and industrial systems, such as diffusers, airfoils, air conditioning plants, moving vehicles... As the separation can strongly influence the performances of such devices, investigating their dynamics and their control is of great interest.A visual sensor developed at PMMH laboratory is first improved to measure in real time the velocity fields and its derived values for flows available in wind tunnels. Based on an optical flow algorithm from the computer vision domain, this new experimental approach makes easier parametric studies and may be used in closed-loop controls.The dynamics of the flow over a flat plate are then investigated. A system identification method - the dynamic observer - is successfully implemented to build a reduced-order model of the transient flow, which captures and predicts well the instabilities generated.Finally, the fully turbulent wake of the square-back Ahmed body is described. Dynamical system tools are applied to characterize it. Using continuous and pulsed micro-jets, different forcing strategies are analyzed. An opposition closed-loop control is implemented, tracking and driving the recirculation.

Advisors/Committee Members: Aider, Jean-Luc (thesis director).

Subjects/Keywords: Contrôle d'écoulements; Flot optique; Sillage; Système dynamique; Flow control; Optical flow; Wake; Dynamical system; 620

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APA (6^th Edition):

Varon, E. (2017). Contrôle réactif d'écoulements décollés à l'aide de PIV temps réel : Closed-loop control separated flows using real-time PIV. (Doctoral Dissertation). Paris Sciences et Lettres (ComUE). Retrieved from http://www.theses.fr/2017PSLET008

Chicago Manual of Style (16^th Edition):

Varon, Eliott. “Contrôle réactif d'écoulements décollés à l'aide de PIV temps réel : Closed-loop control separated flows using real-time PIV.” 2017. Doctoral Dissertation, Paris Sciences et Lettres (ComUE). Accessed April 16, 2021. http://www.theses.fr/2017PSLET008.

MLA Handbook (7^th Edition):

Varon, Eliott. “Contrôle réactif d'écoulements décollés à l'aide de PIV temps réel : Closed-loop control separated flows using real-time PIV.” 2017. Web. 16 Apr 2021.

Vancouver:

Varon E. Contrôle réactif d'écoulements décollés à l'aide de PIV temps réel : Closed-loop control separated flows using real-time PIV. [Internet] [Doctoral dissertation]. Paris Sciences et Lettres (ComUE); 2017. [cited 2021 Apr 16]. Available from: http://www.theses.fr/2017PSLET008.

Council of Science Editors:

Varon E. Contrôle réactif d'écoulements décollés à l'aide de PIV temps réel : Closed-loop control separated flows using real-time PIV. [Doctoral Dissertation]. Paris Sciences et Lettres (ComUE); 2017. Available from: http://www.theses.fr/2017PSLET008

University of Newcastle upon Tyne

14. Mundy, David H. Decentralised control flow : a computational model for distributed systems.

Degree: PhD, 1988, University of Newcastle upon Tyne

URL: http://theses.ncl.ac.uk/jspui/handle/10443/2050 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381525

► This thesis presents two sets of principles for the organisation of distributed computing systems. Details of models of computation based on these principles are together… (more)

▼ This thesis presents two sets of principles for the organisation of distributed computing systems. Details of models of computation based on these principles are together given, with proposals for programming languages based on each model of computation. The recursive control flow principles are based on the concept of recursive control flow computing system structuring. A recursive comprises a group of subordinate computing systems connected together by Each subordinate computing system may either be a communications medium. which a a computing system consists of a processing unit, memory some is itself a recursive component, and input/output devices, or computing components control flow system. The memory of all the computing systems within a recursive control flow computing subordinate system are arranged in a hierarchy. Using suitable addresses, any part of the hierarchy is accessible to any sequence of instructions which may be executed by the processing unit of a subordinate computing system. This rise to serious difficulties in the global accessibility gives understanding of programs written the meaning of in a programming language recursive control flow on the model of computation. based Reasoning about a particular program in isolation is difficult because of the potential interference between the execution different programs cannot be ignored . alternative principles, decentralised control flow, restrict the The accessibility of subordinate global the memory components of the computing The basis of the concept of objects forms the systems. principles. Information channels may flow along unnamed between instances of these objects, this being the only way in which one instance of an object may communicate with some other instance of an object. Reasoning particular program written in a programming language about a based on the decentralised control flow model of computation is easier since it is that there will be no interference between the guaranteed execution of different programs.

Subjects/Keywords: 629.8; Control flow computing system

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APA (6^th Edition):

Mundy, D. H. (1988). Decentralised control flow : a computational model for distributed systems. (Doctoral Dissertation). University of Newcastle upon Tyne. Retrieved from http://theses.ncl.ac.uk/jspui/handle/10443/2050 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381525

Chicago Manual of Style (16^th Edition):

Mundy, David H. “Decentralised control flow : a computational model for distributed systems.” 1988. Doctoral Dissertation, University of Newcastle upon Tyne. Accessed April 16, 2021. http://theses.ncl.ac.uk/jspui/handle/10443/2050 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381525.

MLA Handbook (7^th Edition):

Mundy, David H. “Decentralised control flow : a computational model for distributed systems.” 1988. Web. 16 Apr 2021.

Vancouver:

Mundy DH. Decentralised control flow : a computational model for distributed systems. [Internet] [Doctoral dissertation]. University of Newcastle upon Tyne; 1988. [cited 2021 Apr 16]. Available from: http://theses.ncl.ac.uk/jspui/handle/10443/2050 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381525.

Council of Science Editors:

Mundy DH. Decentralised control flow : a computational model for distributed systems. [Doctoral Dissertation]. University of Newcastle upon Tyne; 1988. Available from: http://theses.ncl.ac.uk/jspui/handle/10443/2050 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381525

Delft University of Technology

15. Van Egmond, J.J. (author). Passive Flow Separation Control for High Lift: An Experimental Investigation on a Novel Vortex Generator.

Degree: 2015, Delft University of Technology

URL: http://resolver.tudelft.nl/uuid:b2328172-746b-4a0b-9937-f2e70f97c224

►

A current focus in the quest for improvement in fuel efficiency in aircraft design is the simplification of complex high lift systems. A simpler high… (more)

▼

A current focus in the quest for improvement in fuel efficiency in aircraft design is the simplification of complex high lift systems. A simpler high lift system in combination with flow separation control is potentially able to meet the current high lift performance requirements, while still reducing overall complexity. Passive flow separation control is promising for its inherent simplicity. This is in line with the main goal of simplification of the high lift system. This thesis covers an exploratory and experimental investigation of a novel type of passive vortex generator: the internal vortex generator. Its distinctive feature, an internal structure for the generation of vortices below the surface, is hypothesized to create strong vortices low inside the boundary layer. Due to this increase in effectiveness the internal vortex generator can potentially outperform external vortex generators. As no literature is currently available on this novel concept, different designs are evaluated using numerical analysis. The wedge type internal vortex generator, similar to a backward wedge external vortex generator, is found to produce the most stable and strong vortices, which are inherently close to the surface. Its close resemblance to the well-documented backward wedge external vortex generator allows for a detailed design that is based on a literature study. Moreover, it allows for an interesting reference case to be present during the experiment test. The internal vortex generator is experimentally tested against its geometrically equivalent external vortex generator. Both vortex generator types are equipped on the same single element high lift model and tested in the Low Speed Low Turbulence Wind Tunnel at the Delft University of Technology. Force measurements indicate a more than 3% increase in maximum lift compared to baseline, while the geometrically equivalent external vortex increases the maximum lift with less than 1%. When the boundary layer is artificially tripped at 0.067 chord length, the internal vortex generator increases maximum lift with 33% compared to baseline, while the external vortex generator increases the lift coefficient with 16%. Due to practical limitations the force measurements do not accurately represent a real-world condition. Critical analysis, strengthened by oil visualizations and XFOIL simulations, suggest that the wedge-type internal vortex generator is capable of achieving more lift than the force measurements indicate. Moreover, the internal vortex generator concept is found to inhibit unique qualities that can be exploited in future research. Overall, the internal vortex generator concept shows to be a viable improvement to regular vortex generators. Therefore, future research is highly encouraged.

Flight Performance and Propulsion

Aerospace Engineering

Advisors/Committee Members: Veldhuis, L.L.M. (mentor).

Subjects/Keywords: vortex generators; high lift system; passive flow control

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APA (6^th Edition):

Van Egmond, J. J. (. (2015). Passive Flow Separation Control for High Lift: An Experimental Investigation on a Novel Vortex Generator. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:b2328172-746b-4a0b-9937-f2e70f97c224

Chicago Manual of Style (16^th Edition):

Van Egmond, J J (author). “Passive Flow Separation Control for High Lift: An Experimental Investigation on a Novel Vortex Generator.” 2015. Masters Thesis, Delft University of Technology. Accessed April 16, 2021. http://resolver.tudelft.nl/uuid:b2328172-746b-4a0b-9937-f2e70f97c224.

MLA Handbook (7^th Edition):

Van Egmond, J J (author). “Passive Flow Separation Control for High Lift: An Experimental Investigation on a Novel Vortex Generator.” 2015. Web. 16 Apr 2021.

Vancouver:

Van Egmond JJ(. Passive Flow Separation Control for High Lift: An Experimental Investigation on a Novel Vortex Generator. [Internet] [Masters thesis]. Delft University of Technology; 2015. [cited 2021 Apr 16]. Available from: http://resolver.tudelft.nl/uuid:b2328172-746b-4a0b-9937-f2e70f97c224.

Council of Science Editors:

Van Egmond JJ(. Passive Flow Separation Control for High Lift: An Experimental Investigation on a Novel Vortex Generator. [Masters Thesis]. Delft University of Technology; 2015. Available from: http://resolver.tudelft.nl/uuid:b2328172-746b-4a0b-9937-f2e70f97c224

Hong Kong University of Science and Technology

16. Wang, Limu. Functional material and its application in digital control of microfluidic devices.

Degree: 2011, Hong Kong University of Science and Technology

URL: http://repository.ust.hk/ir/Record/1783.1-7618 ; https://doi.org/10.14711/thesis-b1160529 ; http://repository.ust.hk/ir/bitstream/1783.1-7618/1/th_redirect.html

► Microfluidics is a low-cost technique for fast-diagnosis and micro-synthesis. Within a decade it might become the foundation of Point-of-Care (POC) and Lab-on-a-Chip (LOC) applications. In… (more)

▼ Microfluidics is a low-cost technique for fast-diagnosis and micro-synthesis. Within a decade it might become the foundation of Point-of-Care (POC) and Lab-on-a-Chip (LOC) applications. In microfluidic research, control of micro-droplets is one of the basic topics. Those pico-liter droplets are perfectly suitable for micro-synthesis, drug screening, and chemical tracing. As a result, large-scale integration and high-density control unions are required. Meanwhile, individual manipulation of micro-droplets remains a challenge: the shortcomings in automatic, reliable and scalable methods for logic control prevent further integration of microfluidic applications. simple control schemes are required while preserving the delicacy of micro-devices. Among the materials that used for microfluidic chip fabrication, Polydimethylsiloxane (PDMS) is one of the most commonly used, not only serving as the stamp for pattern transfer, but also as an unique substrate in chip fabrication owing to its properties such as transparency, biocompatibility, and good flexibility. By employing PDMS, various chip-embedded control modules are realized. However, PDMS is a non-conducting polymer, on which fabricating metallic structures for micro-devices is challenging due to the weak adhesion between the metal and PDMS. Therefore, transport of electric signal is one of the fundamental difficulties to realize digitalized control on PDMS based microfluidic chip, which restricted further development of LOC and POC applications. This thesis presents two approaches to realize digitalized control of microfluid chips. One is to develop functional material, which is CI-PDMS that responds to electric and magnetic field. CI-PDMS is a kind of magnetic elastomer that is fabricated out of PDMS and nano powder. Another approach is to develop micro microstructures and components that provide active control and digitalized response in PDMS based chips. We employed CI-PDMS, AgPDMS and Giant Electrorheological Fluid (GERF), which are smart material that incorporate nano structures, to fabricated micro-pressure sensors, micro-actuators, micro-mixers and micro-logic gate, to convey the electrical signals, and perform chip operation in digitalized approach. We realized the first microfluid based universal logic gate by incorporating the smart material developed in our lab, and provided a facile structure to implement the microfluid logic control by this new logic component. We further proposed a simple and fast chip prototyping method, which is time saving and cost effective to fabricate the microstructure developed in our lab, as an improvement of existing microfluidic chip fabrication technology. In the final part, a summary of these interwoven technologies is presented in the form of technology family tree, while a prospect is provided for the future development of the trend of digitalized microfluidics.

Subjects/Keywords: Microfluidics ; Microfluidic devices ; Digital control systems

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APA (6^th Edition):

Wang, L. (2011). Functional material and its application in digital control of microfluidic devices. (Thesis). Hong Kong University of Science and Technology. Retrieved from http://repository.ust.hk/ir/Record/1783.1-7618 ; https://doi.org/10.14711/thesis-b1160529 ; http://repository.ust.hk/ir/bitstream/1783.1-7618/1/th_redirect.html

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Wang, Limu. “Functional material and its application in digital control of microfluidic devices.” 2011. Thesis, Hong Kong University of Science and Technology. Accessed April 16, 2021. http://repository.ust.hk/ir/Record/1783.1-7618 ; https://doi.org/10.14711/thesis-b1160529 ; http://repository.ust.hk/ir/bitstream/1783.1-7618/1/th_redirect.html.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Wang, Limu. “Functional material and its application in digital control of microfluidic devices.” 2011. Web. 16 Apr 2021.

Vancouver:

Wang L. Functional material and its application in digital control of microfluidic devices. [Internet] [Thesis]. Hong Kong University of Science and Technology; 2011. [cited 2021 Apr 16]. Available from: http://repository.ust.hk/ir/Record/1783.1-7618 ; https://doi.org/10.14711/thesis-b1160529 ; http://repository.ust.hk/ir/bitstream/1783.1-7618/1/th_redirect.html.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Wang L. Functional material and its application in digital control of microfluidic devices. [Thesis]. Hong Kong University of Science and Technology; 2011. Available from: http://repository.ust.hk/ir/Record/1783.1-7618 ; https://doi.org/10.14711/thesis-b1160529 ; http://repository.ust.hk/ir/bitstream/1783.1-7618/1/th_redirect.html

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

NSYSU

17. Ju, Po-yau. Microfluidic Flow Meter and Viscometer Utilizing Flow Induced Vibration Phenomena on an Optic Fiber Cantilever.

Degree: Master, Mechanical and Electro-Mechanical Engineering, 2011, NSYSU

URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0826111-154527

► This study developed a microfluidic flow sensor for the detections of velocity and viscosity, especially for ultra-low viscosity detection. An etched optic fiber with the… (more)

Subjects/Keywords: flow-induced vibration; spectra analysis; flow meter; microfluidic chip; viscometer

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ju, P. (2011). Microfluidic Flow Meter and Viscometer Utilizing Flow Induced Vibration Phenomena on an Optic Fiber Cantilever. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0826111-154527

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ju, Po-yau. “Microfluidic Flow Meter and Viscometer Utilizing Flow Induced Vibration Phenomena on an Optic Fiber Cantilever.” 2011. Thesis, NSYSU. Accessed April 16, 2021. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0826111-154527.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ju, Po-yau. “Microfluidic Flow Meter and Viscometer Utilizing Flow Induced Vibration Phenomena on an Optic Fiber Cantilever.” 2011. Web. 16 Apr 2021.

Vancouver:

Ju P. Microfluidic Flow Meter and Viscometer Utilizing Flow Induced Vibration Phenomena on an Optic Fiber Cantilever. [Internet] [Thesis]. NSYSU; 2011. [cited 2021 Apr 16]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0826111-154527.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ju P. Microfluidic Flow Meter and Viscometer Utilizing Flow Induced Vibration Phenomena on an Optic Fiber Cantilever. [Thesis]. NSYSU; 2011. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0826111-154527

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Alberta

18. Ha, Debbie Feng Shan. Development of Microfluidic Chips and a Customised Flow Control System for use in a Label-Free Cytometer.

Degree: MS, Department of Electrical and Computer Engineering, 2013, University of Alberta

URL: https://era.library.ualberta.ca/files/kw52j912k

► Conventional cytometry uses fluorescently labelled cells that are laborious and costly to prepare. Using a label-free technique, individual cells can be differentiated by light scattering… (more)

Subjects/Keywords: flow control system; biomedical instrumentation; microfludic chip design; flow cytometry; pressure driven flow; light scattering; PDMS; microfluidics; label-free detection

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ha, D. F. S. (2013). Development of Microfluidic Chips and a Customised Flow Control System for use in a Label-Free Cytometer. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/kw52j912k

Chicago Manual of Style (16^th Edition):

Ha, Debbie Feng Shan. “Development of Microfluidic Chips and a Customised Flow Control System for use in a Label-Free Cytometer.” 2013. Masters Thesis, University of Alberta. Accessed April 16, 2021. https://era.library.ualberta.ca/files/kw52j912k.

MLA Handbook (7^th Edition):

Ha, Debbie Feng Shan. “Development of Microfluidic Chips and a Customised Flow Control System for use in a Label-Free Cytometer.” 2013. Web. 16 Apr 2021.

Vancouver:

Ha DFS. Development of Microfluidic Chips and a Customised Flow Control System for use in a Label-Free Cytometer. [Internet] [Masters thesis]. University of Alberta; 2013. [cited 2021 Apr 16]. Available from: https://era.library.ualberta.ca/files/kw52j912k.

Council of Science Editors:

Ha DFS. Development of Microfluidic Chips and a Customised Flow Control System for use in a Label-Free Cytometer. [Masters Thesis]. University of Alberta; 2013. Available from: https://era.library.ualberta.ca/files/kw52j912k

Univerzitet u Beogradu

19. Ilić, Biljana G., 1974-. Хибридни систем управљања струјањем у аеротунелима великих брзина.

Degree: Mašinski fakultet, 2018, Univerzitet u Beogradu

URL: https://fedorabg.bg.ac.rs/fedora/get/o:17821/bdef:Content/get

►

Машинство-Ваздухопловство / Mechanical engineering-Aeronautics

Аеротунели су основни алат на који се ослањају истраживачи у области експерименталне аеродинамике. Настанак, употреба и развој аеротунела су били, а… (more)

▼

Машинство-Ваздухопловство / Mechanical engineering-Aeronautics

Аеротунели су основни алат на који се ослањају истраживачи у области експерименталне аеродинамике. Настанак, употреба и развој аеротунела су били, а и даље јесу, мотивисани заинтересованошћу за широк спектар проблема у аеродинамици, као и чињеницом да теоријске и нумеричке методе не могу да понуде све резултате потребне за доношење одлука о детаљном пројектовању у многим практичним проблемима. Најуспешнији приступ у решавању скоро сваког аеродинамичког проблема базиран је на примени резултата добијених теоријским, експерименталним и нумеричким методама, комбинованих на одговарајући начин и допуњених искуством. Већина светских аеротунела изграђена је пре 50 до 70 година. Слична ситуација је и у аеродинамичкој лабораторији Војнотехничког института у Београду, у оквиру које је најновији аеротунел почео са радом пре неких 30 година. У многим инсталацијама су током радног века увођена извесна технолошка унапређења праћена новим експерименталним техникама, што је омогућавало да се аеротунели увек прилагоде актуелним потребама, упркос томе што су нова решења увођена на појединачној бази, без неке систематске методологије. Међутим, убрзани технолошки развој последњих година је подстакао размишљања о импликацијама на истраживања у будућности, као и о инвестицијама и променама које би требало да се покрену данас у оквиру припрема за неизбежне промене до којих ће доћи у наредних неколико деценија. Резултати студија утицаја технолошког развоја на ангажованост аеротунела, после благог пада почетком 21. века, крајем прве деценије 21. века показују тренд поновног раста, који се делом приписује традиционално високим захтевима војне и ваздухопловне индустрије, а делом неким новим изазовима у области аеродинамичког пројектовања. Резултат тога је да се тренутно у више земаља широм света планира или је у току изградња нових аеротунела. На бази предвиђања индустрије и академске заједнице да ће већина аеротунелских капацитета на различитим нивоима употребе бити потребна током 21. века, у дисертацији су идентификоване кључне области стратегије развоја аеротунела у којима су потребне смернице за испуњавање захтева које доноси будућност. Једна од тих области је управљање, а мотивација за истраживање обављено у оквиру дисертације била је давање смерница за даљи развој у области управљања струјањем у аеротунелима великих брзина. У дисертацији је традиционално разматрање аеротунела као инсталација за обављање стандардних типова аеродинамичких експеримената замењено сагледавањем аеротунела као система за управљање струјањем. Идеја је била да се комбиновањем метода из две области истраживања – аеродинамике и теорије управљања – које се независно развијају већ дуги низ година, стекне бољи увид у физички процес са једне стране, а са друге стране да се идентификује методологија управљања струјањем која би била универзално применљива у аеротунелима великих брзина, а која би донела побољшање тачности експеримената и њихове ефикасности...

Advisors/Committee Members: Stupar, Slobodan, 1951-.

Subjects/Keywords: flow control; experimental aerodynamics; wind tunnel; high-speed wind tunnel; supersonic wind tunnel; compressible flow; cascade control; feedback control; feedforward control; control system synthesis; dynamic model; simulation modelling; hybrid system; hierarchical system; distributed control

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ilić, Biljana G., 1. (2018). Хибридни систем управљања струјањем у аеротунелима великих брзина. (Thesis). Univerzitet u Beogradu. Retrieved from https://fedorabg.bg.ac.rs/fedora/get/o:17821/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ilić, Biljana G., 1974-. “Хибридни систем управљања струјањем у аеротунелима великих брзина.” 2018. Thesis, Univerzitet u Beogradu. Accessed April 16, 2021. https://fedorabg.bg.ac.rs/fedora/get/o:17821/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ilić, Biljana G., 1974-. “Хибридни систем управљања струјањем у аеротунелима великих брзина.” 2018. Web. 16 Apr 2021.

Vancouver:

Ilić, Biljana G. 1. Хибридни систем управљања струјањем у аеротунелима великих брзина. [Internet] [Thesis]. Univerzitet u Beogradu; 2018. [cited 2021 Apr 16]. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:17821/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ilić, Biljana G. 1. Хибридни систем управљања струјањем у аеротунелима великих брзина. [Thesis]. Univerzitet u Beogradu; 2018. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:17821/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Massey University

20. Chou, Steven Chun-Wei. An investigation into the application of microfluidics to the analysis of chromosome conformation.

Degree: MS, Molecular BioScience, 2011, Massey University

URL: http://hdl.handle.net/10179/2804

► Ever since the discovery of DNA, biologists have been striving to unravel its mysteries. Many efforts have been made over the years to further our… (more)

▼ Ever since the discovery of DNA, biologists have been striving to unravel its mysteries. Many efforts have been made over the years to further our understanding of genes, what they do and how they function. Genomes exist as a 3D structure inside the nucleus and they are not randomly arranged. However, there are still many gaps in the knowledge of how the structure fills this 3D space. Using chromosome conformation capture (3C) and other methods based on proximity ligation, interactions between different sections on the chromosome can be captured. A computer simulated 3D chromosome model can then be created based on the interaction data. Currently, global interaction maps can only be created for populations of cells. The overall goal of this research is to develop a protocol that will enable the capture of chromosome interactions within a single cell. This requires the use of microfluidic chips due to the minute quantity of DNA within a single cell. Therefore the main objectives of this research are to: 1) build and test a microfluidic system (lab-on-a-chip or LOC) that will aid in the capture of interand intra- chromosomal interactions of a single cell; and 2) characterize the restriction and ligation of DNA that will be performed in a microfluidic system. In order to assess the efficiency of DNA digestion within microfluidic chips, EcoRI and MspI digestion kinetics within microtubes is first characterized to establish a base line for comparison with digestion kinetics within microfluidic chips. The Km, Vmax and Kcat for EcoRI within microtubes are 32 nM, 0.14 nM s-1 and 1.4 fmol s-1 U-1 respectively. The Km, Vmax and Kcat for MspI within microtubes are 125 nM, 1.46 nM s-1 and 29.2 fmol s-1 U-1 respectively. On the other hand, the digestion kinetics within microfluidic chips is undetermined, because both restriction enzymes exhibit non-specific nuclease activity within microfluidic chips under the conditions tested. The exhibition of non-specific nuclease activity is unexpected and causes ligation of DNA performed in microfluidic chips to fail. The non-specific nuclease activity of EcoRI and MspI within microfluidic chips is also problematic for the overall goal of developing a protocol that will enable the capture of chromosome interactions within a single cell, because the non-specific nuclease activity would cause loss of template and random variations in results obtained.

Subjects/Keywords: Chromosome analysis; Lab-on-a-chip; Microfluidic system; Microfluidic chips; Chromosome interactions

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Chou, S. C. (2011). An investigation into the application of microfluidics to the analysis of chromosome conformation. (Masters Thesis). Massey University. Retrieved from http://hdl.handle.net/10179/2804

Chicago Manual of Style (16^th Edition):

Chou, Steven Chun-Wei. “An investigation into the application of microfluidics to the analysis of chromosome conformation.” 2011. Masters Thesis, Massey University. Accessed April 16, 2021. http://hdl.handle.net/10179/2804.

MLA Handbook (7^th Edition):

Chou, Steven Chun-Wei. “An investigation into the application of microfluidics to the analysis of chromosome conformation.” 2011. Web. 16 Apr 2021.

Vancouver:

Chou SC. An investigation into the application of microfluidics to the analysis of chromosome conformation. [Internet] [Masters thesis]. Massey University; 2011. [cited 2021 Apr 16]. Available from: http://hdl.handle.net/10179/2804.

Council of Science Editors:

Chou SC. An investigation into the application of microfluidics to the analysis of chromosome conformation. [Masters Thesis]. Massey University; 2011. Available from: http://hdl.handle.net/10179/2804

Oregon State University

21. Weymann, Davis. Properties of hydrogels for immobilization of bacteria in a commercial microfluidic dioreactor.

Degree: MS, 2017, Oregon State University

URL: http://hdl.handle.net/1957/61554

► Current technological shortcomings limit the economic viability of capturing and utilizing small sources of methane. The development of a reactor to overcome these limitations would… (more)

▼ Current technological shortcomings limit the economic viability of capturing and utilizing small sources of methane. The development of a reactor to overcome these limitations would unlock economic opportunity and incentivize reduced methane emissions. A microfluidic bioreactor containing immobilized methanotrophs has the potential to overcome these limitations by profitably converting small quantities of methane to more valuable liquid products. The material used for immobilizing bacteria in a microfluidic bioreactor must meet four criteria: biocompatibility, mechanical stability, reactor adhesion, and economic viability. This paper describes the development of a novel blend of agar and cross-linked polyvinyl alcohol (PVA) that meets these requirements. The properties of agar/PVA blend hydrogels strongly depend on the ratio and absolute concentration of the constituent polymers, and the processes by which the polymers are cross-linked. The microscopic morphology of these blend hydrogels is theorized to be two interacting and competing phases formed by agar and PVA molecules mutually interfering with cross-linking via hydrogen bonding, and separating due to spinodal decomposition. Evidence for the proposed morphology is discussed. Blend hydrogels of 2/5% agar/PVA are particularly promising, combining the desirable properties of both agar (low swelling) and PVA (strength and adhesion). The 2/5% agar/PVA gels exhibited little swelling in water and nitrate mineral salts-based media. They also adhered to polycarbonate and stainless steel surfaces treated with ozone or oxygen plasma. Cultures of Methylomicrobium buryatense 5GB1 (5GB1) immobilized in these gels showed a reduction of metabolic activity rates, partly due to exposure to high concentrations of sulfate and phosphate during cross-linking. Shortening cross-linker exposure time from 2 hours to 30 minutes greatly improved activity rates, and immobilized cells exhibited increased activity rates over time as fresh methane was added. Based on these results, the 2/5% agar/PVA blend hydrogels are suitable for the immobilization of 5GB1 in a microfluidic bioreactor. Further improvement of activity rates may be possible. Preservation of 5GB1 by lyophilization was unsuccessful. Cultures preserved in solutions of 5% bovine serum albumin and 10% sucrose or trehalose maintained metabolic activity rates after freezing at -80°C, but showed no activity after lyophilization. Advisors/Committee Members: Schilke, Karl (advisor), Jovanovic, Goran (committee member).

Subjects/Keywords: Microfluidic

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Weymann, D. (2017). Properties of hydrogels for immobilization of bacteria in a commercial microfluidic dioreactor. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/61554

Chicago Manual of Style (16^th Edition):

Weymann, Davis. “Properties of hydrogels for immobilization of bacteria in a commercial microfluidic dioreactor.” 2017. Masters Thesis, Oregon State University. Accessed April 16, 2021. http://hdl.handle.net/1957/61554.

MLA Handbook (7^th Edition):

Weymann, Davis. “Properties of hydrogels for immobilization of bacteria in a commercial microfluidic dioreactor.” 2017. Web. 16 Apr 2021.

Vancouver:

Weymann D. Properties of hydrogels for immobilization of bacteria in a commercial microfluidic dioreactor. [Internet] [Masters thesis]. Oregon State University; 2017. [cited 2021 Apr 16]. Available from: http://hdl.handle.net/1957/61554.

Council of Science Editors:

Weymann D. Properties of hydrogels for immobilization of bacteria in a commercial microfluidic dioreactor. [Masters Thesis]. Oregon State University; 2017. Available from: http://hdl.handle.net/1957/61554

Indian Institute of Science

22. Jagannadh, Veerendra Kalyan. Point-of-Care High-throughput Optofluidic Microscope for Quantitative Imaging Cytometry.

Degree: PhD, Faculty of Engineering, 2018, Indian Institute of Science

URL: http://etd.iisc.ac.in/handle/2005/3274

► Biological research and Clinical Diagnostics heavily rely on Optical Microscopy for analyzing properties of cells. The experimental protocol for con-ducting a microscopy based diagnostic test… (more)

▼ Biological research and Clinical Diagnostics heavily rely on Optical Microscopy for analyzing properties of cells. The experimental protocol for con-ducting a microscopy based diagnostic test consists of several manual steps, like sample extraction, slide preparation and inspection. Recent advances in optical microscopy have predominantly focused on resolution enhancement. Whereas, the aspect of automating the manual steps and enhancing imaging throughput were relatively less explored. Cost-e ective automation of clinical microscopy would potentially enable the creation of diagnostic devices with a wide range of medical and biological applications. Further, automation plays an important role in enabling diagnostic testing in resource-limited settings. This thesis presents a novel optofluidics based approach for automation of clinical diagnostic microscopy. A system-level integrated optofluidic architecture, which enables the automation of overall diagnostic work- ow has been proposed. Based on the proposed architecture, three different prototypes, which can enable point-of-care (POC) imaging cytometry have been developed. The characterization of these prototypes has been performed. Following which, the applicability of the platform for usage in diagnostic testing has been validated. The prototypes were used to demonstrate applications like Cell Viability Assay, Red Blood Cell Counting, Diagnosis of Malaria and Spherocytosis. An important performance metric of the device is the throughput (number of cells imaged per second). A novel microfluidic channel design, capable of enabling imaging throughputs of about 2000 cells per second has been incorporated into the instrument. Further, material properties of the sample handling component (microfluidic device) determine several functional aspects of the instrument. Ultrafast-laser inscription (ULI) based glass microfluidic devices have been identi ed and tested as viable alternatives to Polydimethylsiloxane (PDMS) based microfluidic chips. Cellular imaging with POC platforms has thus far been limited to acquisition of 2D morphology. To potentially enable 3D cellular imaging with POC platforms, a novel slanted channel microfluidic chip design has been proposed. The proposed design has been experimentally validated by performing 3D imaging of fluorescent microspheres and cells. It is envisaged that the proposed innovation would aid to the current e orts towards implementing good quality health-care in rural scenarios. The thesis is organized in the following manner : The overall thesis can be divided into two parts. The first part (chapters 2, 3) of the thesis deals with the optical aspects of the proposed Optofluidic instrument (development, characterization and validations demonstrating its use in poc diagnostic applications). The second part (chapters 4,5,6) of the thesis details the microfluidic sample handling aspects implemented with the help of custom fabricated microfludic devices, the integration of the prototype, func-tional framework of the device. Chapter 2… Advisors/Committee Members: Gorthi, Sai Siva (advisor).

Subjects/Keywords: Optofluidic Microscope; Quantitative Imaging Cytometry; Quantitative Morphometry; Cell Enumeration; Optical System Characterization; Point-of-Care Cytometry; Imaging Flow Cytometry; Optofluidic Imaging Flow Analyzer; Microfluidic Microscopy; Microfluidics; Ultrafast-laser inscription (ULI); Polydimethylsiloxane (PDMS); Instrumentation

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Jagannadh, V. K. (2018). Point-of-Care High-throughput Optofluidic Microscope for Quantitative Imaging Cytometry. (Doctoral Dissertation). Indian Institute of Science. Retrieved from http://etd.iisc.ac.in/handle/2005/3274

Chicago Manual of Style (16^th Edition):

Jagannadh, Veerendra Kalyan. “Point-of-Care High-throughput Optofluidic Microscope for Quantitative Imaging Cytometry.” 2018. Doctoral Dissertation, Indian Institute of Science. Accessed April 16, 2021. http://etd.iisc.ac.in/handle/2005/3274.

MLA Handbook (7^th Edition):

Jagannadh, Veerendra Kalyan. “Point-of-Care High-throughput Optofluidic Microscope for Quantitative Imaging Cytometry.” 2018. Web. 16 Apr 2021.

Vancouver:

Jagannadh VK. Point-of-Care High-throughput Optofluidic Microscope for Quantitative Imaging Cytometry. [Internet] [Doctoral dissertation]. Indian Institute of Science; 2018. [cited 2021 Apr 16]. Available from: http://etd.iisc.ac.in/handle/2005/3274.

Council of Science Editors:

Jagannadh VK. Point-of-Care High-throughput Optofluidic Microscope for Quantitative Imaging Cytometry. [Doctoral Dissertation]. Indian Institute of Science; 2018. Available from: http://etd.iisc.ac.in/handle/2005/3274

Indian Institute of Science

23. Banoth, Earu. Absorption Flow-Cytometry for Point-of-Care Diagnostics.

Degree: PhD, Faculty of Engineering, 2018, Indian Institute of Science

URL: http://etd.iisc.ac.in/handle/2005/3620

► Medical devices are used widely at every stage of disease diagnosis and treatment. To eradicate certain infectious diseases, the development of highly sensitive diagnostic tools… (more)

▼ Medical devices are used widely at every stage of disease diagnosis and treatment. To eradicate certain infectious diseases, the development of highly sensitive diagnostic tools and techniques is essential. The work reported in this thesis presents a novel approach, which can be used for the diagnosis of various diseases in the field of clinical cytology. The central theme of this approach was to develop a simple, holistic and completely automated system for point-of-care (POC) diagnostics. This is realized through the Development of an Absorption Flow-Cytometer with Synergistic Integration of Microfluidic, Optics and simple Electronics. Quantitative diagnosis of malaria has been taken as test case for the characterization and validation of the developed technology. Malaria is a life-threatening disease widely prevalent in developing countries. Approximately half the world population undergoes a test of malaria and it kills close to half a million people every year. Early detection and treatment will reduce the number of fatalities and also decrease its transmission rate. In the recent past, several diagnostic tools have been developed to detect malaria but there are varied demands on diagnostic instruments in healthcare settings and endemic contexts. The objective of this thesis is to develop an instrument capable of identifying malaria-infected red blood cells (i-RBCs) from a given few micro-liters of whole blood. The optical absorption properties of blood cells were measured at a single-cell level to diagnose malaria. The proof-of-concept for the instrument was established in four stages, after which a prototype was also developed and validated. In the first stage, a system capable of simultaneously imaging cells and also measuring their optical absorbance properties was developed. The developed system was employed to characterize absorption properties of red blood cells (malaria-infected and healthy ones) on blood-smear. A custom-made bright-field transmission microscope in combination with a pair of laser diode and photo-detector was used to simultaneously image and measure transmittance of infected and uninfected RBCs. In the second stage, the technique was extended to enable high-throughput measurements with the use of microfluidic sample handling and synchronous data acquisition. Using this technique, the optical absorbance and morphology of infected and healthy RBCs have been characterized in statistically significant numbers. The correlation between cell morphology (from images) and single-cell optical absorbance level helped to establish the thresholds for differentiating healthy and infected cells. In the third stage, a portable prototype capable of assessing optical absorbance levels of single cells was fabricated. The developed prototype is capable of assessing cells at throughputs of about 1800 cells/ second. It was initially validated with sample suspensions containing infected and healthy RBCs obtained from malaria cultures. For the device to be usable at the field-level, it has to function in… Advisors/Committee Members: Gorthi, Sai Siva (advisor).

Subjects/Keywords: Absorption Flow-Cytometry; Qualitative Diagnosis - Malaria; Absorption Flow Analyzer; Point-of-Care (POC) Diiagnostics; Malaria Diagnostic Testing; Optofluidic Hyper-Imaging System; Microfluidics; Malaria Infected Red Blood Cells (iRBCs); Microfluidic Microscopy; Malaria Diagnosis; Malaria Detection; Instrumentation

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Banoth, E. (2018). Absorption Flow-Cytometry for Point-of-Care Diagnostics. (Doctoral Dissertation). Indian Institute of Science. Retrieved from http://etd.iisc.ac.in/handle/2005/3620

Chicago Manual of Style (16^th Edition):

Banoth, Earu. “Absorption Flow-Cytometry for Point-of-Care Diagnostics.” 2018. Doctoral Dissertation, Indian Institute of Science. Accessed April 16, 2021. http://etd.iisc.ac.in/handle/2005/3620.

MLA Handbook (7^th Edition):

Banoth, Earu. “Absorption Flow-Cytometry for Point-of-Care Diagnostics.” 2018. Web. 16 Apr 2021.

Vancouver:

Banoth E. Absorption Flow-Cytometry for Point-of-Care Diagnostics. [Internet] [Doctoral dissertation]. Indian Institute of Science; 2018. [cited 2021 Apr 16]. Available from: http://etd.iisc.ac.in/handle/2005/3620.

Council of Science Editors:

Banoth E. Absorption Flow-Cytometry for Point-of-Care Diagnostics. [Doctoral Dissertation]. Indian Institute of Science; 2018. Available from: http://etd.iisc.ac.in/handle/2005/3620

NSYSU

24. Chiou, Kai-sheng. A Multimodal Microphone Control System.

Degree: Master, Computer Science and Engineering, 2015, NSYSU

URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0614115-120518

► Though there are many types of meeting room microphone control system in the market, the most common control method can be classified into either push-button… (more)

Subjects/Keywords: Skin color detection; Nose detection; Behavior detection; Optical flow; Microphone control system

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APA (6^th Edition):

Chiou, K. (2015). A Multimodal Microphone Control System. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0614115-120518

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Chiou, Kai-sheng. “A Multimodal Microphone Control System.” 2015. Thesis, NSYSU. Accessed April 16, 2021. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0614115-120518.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Chiou, Kai-sheng. “A Multimodal Microphone Control System.” 2015. Web. 16 Apr 2021.

Vancouver:

Chiou K. A Multimodal Microphone Control System. [Internet] [Thesis]. NSYSU; 2015. [cited 2021 Apr 16]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0614115-120518.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Chiou K. A Multimodal Microphone Control System. [Thesis]. NSYSU; 2015. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0614115-120518

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of California – Berkeley

25. Arnold, Daniel Brian. Model-Free Optimal Control of Distributed Energy Resources in Electric Power Distribution Systems.

Degree: Mechanical Engineering, 2015, University of California – Berkeley

URL: http://www.escholarship.org/uc/item/3r30q0tb

► Distributed Energy Resources (DER) have the potential to both improve the manner in which the electric power distribution system is operated and provide services to… (more)

Subjects/Keywords: Electrical engineering; Mechanical engineering; distributed generation; Extremum Seeking; optimal power flow; power system control

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APA (6^th Edition):

Arnold, D. B. (2015). Model-Free Optimal Control of Distributed Energy Resources in Electric Power Distribution Systems. (Thesis). University of California – Berkeley. Retrieved from http://www.escholarship.org/uc/item/3r30q0tb

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Arnold, Daniel Brian. “Model-Free Optimal Control of Distributed Energy Resources in Electric Power Distribution Systems.” 2015. Thesis, University of California – Berkeley. Accessed April 16, 2021. http://www.escholarship.org/uc/item/3r30q0tb.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Arnold, Daniel Brian. “Model-Free Optimal Control of Distributed Energy Resources in Electric Power Distribution Systems.” 2015. Web. 16 Apr 2021.

Vancouver:

Arnold DB. Model-Free Optimal Control of Distributed Energy Resources in Electric Power Distribution Systems. [Internet] [Thesis]. University of California – Berkeley; 2015. [cited 2021 Apr 16]. Available from: http://www.escholarship.org/uc/item/3r30q0tb.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Arnold DB. Model-Free Optimal Control of Distributed Energy Resources in Electric Power Distribution Systems. [Thesis]. University of California – Berkeley; 2015. Available from: http://www.escholarship.org/uc/item/3r30q0tb

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Addis Ababa University

26. Mikias, Hailu. DYNAMIC MODELING AND TECHNO-ECONOMIC ANALYSIS OF PV-WIND-FUEL CELL HYBRID POWER SYSTEM: THE CASE STUDY OF NIFASSO .

Degree: 2014, Addis Ababa University

URL: http://etd.aau.edu.et/dspace/handle/123456789/5051

► Due to ever increasing energy consumption, rising public awareness of environmental protection and steady progress in distributed generation, alternative (i.e., renewable and fuel cell based)… (more)

▼ Due to ever increasing energy consumption, rising public awareness of environmental protection and steady progress in distributed generation, alternative (i.e., renewable and fuel cell based) distributed generation (DG) systems have attracted increased interest. Wind and photovoltaic (PV) based power generation are two of the most promising renewable energy technologies. Fuel cell (FC) systems also show great potential in DG applications of the future due to their fast technological development and the merits they have, such as high efficiency, zero or low emissions (of pollutant gases) and flexible modular structure. In this thesis work, the techno-economic feasibility study (using HOMER) of emission free hybrid power system of solar, wind and fuel cell power source unit for a given rural village (Nifasso) that can meet the electricity demand in a sustainable manner has been studied. The main power for the hybrid system comes from the solar and wind energy while the fuel cell and rechargeable batteries are used as a secondary and primary energy back up units respectively. The modeling and control of a hybrid PV-Wind-FC DG system is also addressed. Dynamic models for the major system components, namely, wind energy conversion system (WECS), PV energy conversion system (PVECS), fuel cell, electrolyzer, inverter, battery, hydrogen storage tank and an overall power flow controller unit are developed. Then, a simulation model for the proposed hybrid power system has been developed using MATLAB/Simulink environment. This is done by creating a subsystem and masked block sets of the major dynamic component models and then cascading (assembling) in to a single aggregate model. The overall power management strategy for coordinating and/or controlling power flows among the different energy sources is also presented in the thesis. Simulations have been carried out to verify the system dynamic performance using a practical load profile and weather data. The result show that the overall power management strategy is effective and the load demand is balanced successfully. To make the thesis work complete, a grid extension from the closest substation has been designed. Cost of the grid extension is estimated based on the data obtained from EEPCoUEAP office. This is done in order to compare the cost of the designed hybrid RES power system against the cost of grid extension. The result shows that breakeven grid extension distance to be 25.1 km which indicates that grid extension is preferable. Advisors/Committee Members: Dr. Getachew Bekele Beyene (advisor).

Subjects/Keywords: PV-Wind-Fuel Cell Hybrid Power System; Dynamic Modeling; TechnoEconomic; Power Flow Control

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APA (6^th Edition):

Mikias, H. (2014). DYNAMIC MODELING AND TECHNO-ECONOMIC ANALYSIS OF PV-WIND-FUEL CELL HYBRID POWER SYSTEM: THE CASE STUDY OF NIFASSO . (Thesis). Addis Ababa University. Retrieved from http://etd.aau.edu.et/dspace/handle/123456789/5051

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Mikias, Hailu. “DYNAMIC MODELING AND TECHNO-ECONOMIC ANALYSIS OF PV-WIND-FUEL CELL HYBRID POWER SYSTEM: THE CASE STUDY OF NIFASSO .” 2014. Thesis, Addis Ababa University. Accessed April 16, 2021. http://etd.aau.edu.et/dspace/handle/123456789/5051.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Mikias, Hailu. “DYNAMIC MODELING AND TECHNO-ECONOMIC ANALYSIS OF PV-WIND-FUEL CELL HYBRID POWER SYSTEM: THE CASE STUDY OF NIFASSO .” 2014. Web. 16 Apr 2021.

Vancouver:

Mikias H. DYNAMIC MODELING AND TECHNO-ECONOMIC ANALYSIS OF PV-WIND-FUEL CELL HYBRID POWER SYSTEM: THE CASE STUDY OF NIFASSO . [Internet] [Thesis]. Addis Ababa University; 2014. [cited 2021 Apr 16]. Available from: http://etd.aau.edu.et/dspace/handle/123456789/5051.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Mikias H. DYNAMIC MODELING AND TECHNO-ECONOMIC ANALYSIS OF PV-WIND-FUEL CELL HYBRID POWER SYSTEM: THE CASE STUDY OF NIFASSO . [Thesis]. Addis Ababa University; 2014. Available from: http://etd.aau.edu.et/dspace/handle/123456789/5051

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

27. Wang, Jiacheng. Developing of Data Logging System for Flow Test Station in Industrial Laboratory.

Degree: Engineering Science, 2016, University of Skövde

URL: http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-13120

► CEJN is a leading transnational company with long history and professional background providing high-tech quick connect products in global market. The headquarters of the… (more)

▼ CEJN is a leading transnational company with long history and professional background providing high-tech quick connect products in global market. The headquarters of the com-pany in Skövde, Sweden, is the birthplace and core location of the entire corporation. In the headquarters, the engineer tests their products at their flow test laboratory. In the laboratory, there are flow test stations for all product ranges. Within them, the most basic are flow test benches for air, water and hydraulic oil products. The flow test benches are aim to test the products under International/Swedish standard conditions to determine the performance. This project is aimed in upgrading the test benches by engineering both hardware and soft-ware, to achieve higher level of automation of the data logging system used in the lab. All three test benches were designed and installed following requirements in corresponding in-ternational standards. The principles of testing are similar, but they are not developed from the same era, and the automation level of each test bench differs. As a result, the need of up-grading in the benches is different. In the laboratory, the recorded test results are reorganized and processed by a report genera-tor developed on Microsoft Excel. The Excel report generator is used for organize test results, calibrate the deviation of the instruments, calculate the flow coefficient of the product, gener-ate performance diagrams of the products, generate test reports for different purpose of use, and save the test data and results on the server of the company. Above all, an upgrade of the data logging system for the three flow test benches was needed. Depending on the conditions of each test bench, the project is implemented and designed the following three parts: • A hardware upgrading (flow rate computer) for the air flow test benchA new signal indicating device for replacing the old flow rate computer is purchased from Italy by the company. The new instrument contains filter function to stabilize the flow rate value. • A software upgrading (Excel report generator) for all the test benchesVisual Basic for Applications (VBA) programming language is used for developing functions such as data communication, signal decoding and user interface developing in Excel. • Develop of an automated data visualizing system for the air flow test benchData communication from the new instrument to a PC through serial port and Mod-bus RTU interface is established. The data visualizing function is compiled in the Ex-cel report generator for the air flow test, realized by VBA programming.

Subjects/Keywords: data logging system; flow test laboratory; Control Engineering; Reglerteknik; Signal Processing; Signalbehandling; Communication Systems; Kommunikationssystem

11 more images…

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APA (6^th Edition):

Wang, J. (2016). Developing of Data Logging System for Flow Test Station in Industrial Laboratory. (Thesis). University of Skövde. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-13120

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Wang, Jiacheng. “Developing of Data Logging System for Flow Test Station in Industrial Laboratory.” 2016. Thesis, University of Skövde. Accessed April 16, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-13120.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Wang, Jiacheng. “Developing of Data Logging System for Flow Test Station in Industrial Laboratory.” 2016. Web. 16 Apr 2021.

Vancouver:

Wang J. Developing of Data Logging System for Flow Test Station in Industrial Laboratory. [Internet] [Thesis]. University of Skövde; 2016. [cited 2021 Apr 16]. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-13120.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Wang J. Developing of Data Logging System for Flow Test Station in Industrial Laboratory. [Thesis]. University of Skövde; 2016. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-13120

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of KwaZulu-Natal

28. Kasie, Fentahun Moges. Development of a decision support system for decision-based part/fixture assignment and fixture flow control.

Degree: 2018, University of KwaZulu-Natal

URL: https://researchspace.ukzn.ac.za/handle/10413/17252

► An intense competition in a dynamic situation has increased the requirements that must be considered in the current manufacturing systems. Among those factors, fixtures are… (more)

▼ An intense competition in a dynamic situation has increased the requirements that must be considered in the current manufacturing systems. Among those factors, fixtures are one of the major problematic components. The cost of fixture design and manufacture contributes to 10-20% of production costs. Manufacturing firms usually use traditional methods for part/fixture assignment works. These methods are highly resource consuming and cumbersome to enumerate the available fixtures and stabilise the number of fixtures required in a system. The aim of this study was to research and develop a Decision Support System (DSS), which was useful to perform a decision-based part/fixture assignment and fixture flow control during planned production periods. The DSS was designed to assist its users to reuse/adapt the retrieved fixtures or manufacture new fixtures depending upon the state of the retrieved fixtures and the similarities between the current and retrieved cases. This DSS combined Case-Based Reasoning (CBR), fuzzy set theory, the Analytic Hierarchy Process (AHP) and Discrete-Event Simulation (DES) techniques. The Artificial Intelligence (AI) component of the DSS immensely used a fuzzy CBR system combined with the fuzzy AHP and guiding rules from general domain knowledge. The fuzzy CBR was used to represent the uncertain and imprecise values of case attributes. The fuzzy AHP was applied to elicit domain knowledge from experts to prioritise case attributes. New part orders and training samples were represented as new and prior cases respectively using an Object-Oriented (OO) method for case retrieval and decision proposal. Popular fuzzy ranking and similarity measuring approaches were utilised in the case retrieval process. A DES model was implemented to analyse the performances of the proposed solutions by the fuzzy CBR subsystem. Three scenarios were generated by this subsystem as solution alternatives that were the proposed numbers of fixtures. The performances of these scenarios were evaluated using the DES model and the best alternative was identified. The novelty of this study employed the combination of fuzzy CBR and DES methods since such kinds of combinations have not been addressed yet. A numerical example was illustrated to present the soundness of the proposed methodological approach. Keywords: Decision support systems, case-based reasoning, analytic hierarchy process, fuzzy set theory, object-oriented methods, discrete-event simulation, fixtures. Advisors/Committee Members: Bright, Glen. (advisor), Walker, Anthony John. (advisor).

Subjects/Keywords: Decision support system.; Decision-based part.; Fixture assignment.; Fixture flow control.; Case-Based Reasoning (CBR).

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APA (6^th Edition):

Kasie, F. M. (2018). Development of a decision support system for decision-based part/fixture assignment and fixture flow control. (Thesis). University of KwaZulu-Natal. Retrieved from https://researchspace.ukzn.ac.za/handle/10413/17252

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kasie, Fentahun Moges. “Development of a decision support system for decision-based part/fixture assignment and fixture flow control.” 2018. Thesis, University of KwaZulu-Natal. Accessed April 16, 2021. https://researchspace.ukzn.ac.za/handle/10413/17252.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kasie, Fentahun Moges. “Development of a decision support system for decision-based part/fixture assignment and fixture flow control.” 2018. Web. 16 Apr 2021.

Vancouver:

Kasie FM. Development of a decision support system for decision-based part/fixture assignment and fixture flow control. [Internet] [Thesis]. University of KwaZulu-Natal; 2018. [cited 2021 Apr 16]. Available from: https://researchspace.ukzn.ac.za/handle/10413/17252.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kasie FM. Development of a decision support system for decision-based part/fixture assignment and fixture flow control. [Thesis]. University of KwaZulu-Natal; 2018. Available from: https://researchspace.ukzn.ac.za/handle/10413/17252

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Illinois – Urbana-Champaign

29. Ujcich, Benjamin E. Securing the software-defined networking control plane by using control and data dependency techniques.

Degree: PhD, Electrical & Computer Engr, 2020, University of Illinois – Urbana-Champaign

URL: http://hdl.handle.net/2142/108612

► Software-defined networking (SDN) fundamentally changes how network and security practitioners design, implement, and manage their networks. SDN decouples the decision-making about traffic forwarding (i.e., the… (more)

▼ Software-defined networking (SDN) fundamentally changes how network and security practitioners design, implement, and manage their networks. SDN decouples the decision-making about traffic forwarding (i.e., the control plane) from the traffic being forwarded (i.e., the data plane). SDN also allows for network applications, or apps, to programmatically control network forwarding behavior and policy through a logically centralized control plane orchestrated by a set of SDN controllers. As a result of logical centralization, SDN controllers act as network operating systems in the coordination of shared data plane resources and comprehensive security policy implementation. SDN can support network security through the provision of security services and the assurances of policy enforcement. However, SDN’s programmability means that a network’s security considerations are different from those of traditional networks. For instance, an adversary who manipulates the programmable control plane can leverage significant control over the data plane’s behavior. In this dissertation, we demonstrate that the security posture of SDN can be enhanced using control and data dependency techniques that track information flow and enable understanding of application composability, control and data plane decoupling, and control plane insight. We support that statement through investigation of the various ways in which an attacker can use control flow and data flow dependencies to influence the SDN control plane under different threat models. We systematically explore and evaluate the SDN security posture through a combination of runtime, pre-runtime, and post-runtime contributions in both attack development and defense designs. We begin with the development a conceptual accountability framework for SDN. We analyze the extent to which various entities within SDN are accountable to each other, what they are accountable for, mechanisms for assurance about accountability, standards by which accountability is judged, and the consequences of breaching accountability. We discover significant research gaps in SDN’s accountability that impact SDN’s security posture. In particular, the results of applying the accountability framework showed that more control plane attribution is necessary at different layers of abstraction, and that insight motivated the remaining work in this dissertation. Next, we explore the influence of apps in the SDN control plane’s secure operation. We find that existing access control protections that limit what apps can do, such as role-based access controls, prove to be insufficient for preventing malicious apps from damaging control plane operations. The reason is SDN’s reliance on shared network state. We analyze SDN’s shared state model to discover that benign apps can be tricked into acting as “confused deputies”; malicious apps can poison the state used by benign apps, and that leads the benign apps to make decisions that negatively affect the network. That violates an implicit (but unenforced) integrity policy that… Advisors/Committee Members: Sanders, William H (advisor), Sanders, William H (Committee Chair), Bates, Adam (committee member), Gunter, Carl A (committee member), Iyer, Ravishankar K (committee member).

Subjects/Keywords: software-defined networking (SDN); network operating system; Open Network Operating System (ONOS); data provenance; program analysis; access control; information flow control (IFC); vulnerability discovery; exploit generation; causal analysis; information flow; data flow; control flow; accountability; security; computer networking; network applications; ProvSDN; EventScope; PicoSDN

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APA (6^th Edition):

Ujcich, B. E. (2020). Securing the software-defined networking control plane by using control and data dependency techniques. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/108612

Chicago Manual of Style (16^th Edition):

Ujcich, Benjamin E. “Securing the software-defined networking control plane by using control and data dependency techniques.” 2020. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed April 16, 2021. http://hdl.handle.net/2142/108612.

MLA Handbook (7^th Edition):

Ujcich, Benjamin E. “Securing the software-defined networking control plane by using control and data dependency techniques.” 2020. Web. 16 Apr 2021.

Vancouver:

Ujcich BE. Securing the software-defined networking control plane by using control and data dependency techniques. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2020. [cited 2021 Apr 16]. Available from: http://hdl.handle.net/2142/108612.

Council of Science Editors:

Ujcich BE. Securing the software-defined networking control plane by using control and data dependency techniques. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2020. Available from: http://hdl.handle.net/2142/108612

NSYSU

30. Wu, Jia-Lin. Simultaneously Optimized Control Pins Placement and Channels Routing of Control-Layer in Flow-Based Microfluidic Biochips.

Degree: Master, Computer Science and Engineering, 2017, NSYSU

URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0023117-100523

► Due to the advances in micro-electromechanical systems (MEMS), the lab-on-a-chip (LOC) has been developed. There are many applications of lab-on-a-chip devices, including point-of-care disease diagnostics,… (more)

Subjects/Keywords: biochip; lab-on-a-chip; continuous flow; routing; microfluidic

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APA (6^th Edition):

Wu, J. (2017). Simultaneously Optimized Control Pins Placement and Channels Routing of Control-Layer in Flow-Based Microfluidic Biochips. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0023117-100523

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Wu, Jia-Lin. “Simultaneously Optimized Control Pins Placement and Channels Routing of Control-Layer in Flow-Based Microfluidic Biochips.” 2017. Thesis, NSYSU. Accessed April 16, 2021. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0023117-100523.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Wu, Jia-Lin. “Simultaneously Optimized Control Pins Placement and Channels Routing of Control-Layer in Flow-Based Microfluidic Biochips.” 2017. Web. 16 Apr 2021.

Vancouver:

Wu J. Simultaneously Optimized Control Pins Placement and Channels Routing of Control-Layer in Flow-Based Microfluidic Biochips. [Internet] [Thesis]. NSYSU; 2017. [cited 2021 Apr 16]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0023117-100523.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Wu J. Simultaneously Optimized Control Pins Placement and Channels Routing of Control-Layer in Flow-Based Microfluidic Biochips. [Thesis]. NSYSU; 2017. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0023117-100523

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Open Access Theses and Dissertations