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1.
Gilardin, Laurent.
Identification des épitopes T d’ADAMTS13 chez les patients atteints de Purpura Thrombotique Thrombocytopénique : ADAMTS13 T cell epitope identification in ThromboticThrombocytopenic Purpura patients.
Degree: Docteur es, Sciences de la vie et de la santé, 2019, Université Paris-Saclay (ComUE)
URL: http://www.theses.fr/2019SACLS520 
► Le purpura thrombotique thrombocytopénique (PTT) est une maladie autoimmune rare et grave caractérisée par la présence d’anticorps dirigés contre ADAMTS13 (A13), une protéase impliquée dans…
(more)
▼ Le purpura thrombotique thrombocytopénique (PTT) est une maladie autoimmune rare et grave caractérisée par la présence d’anticorps dirigés contre ADAMTS13 (A13), une protéase impliquée dans l’hémostase primaire. L’implication des lymphocytes T CD4⁺ spécifiques d’ADAMTS13, dans la physiopathologie de la maladie est suggérée par une restriction pour l’haplotype HLA-DRB1*11 (DR11), l’isotype IgG des anticorps. Dans ce travail, nous avons cherché à identifier les épitopes T d’A13. Tout d’abord, nous avons sélectionné in silico les peptides d’A13 susceptibles d’être présentés par les molécules HLA-DR11. Ensuite, l’étude de la liaison de ces peptides à des molécules HLA-DR11 par des tests ELISA compétitifs a permis d’identifier les peptides les plus affins. Enfin, nous avons déterminé les peptides d’ADAMTS13 reconnus par les lymphocytes T CD4⁺ de donneurs sains et de patients porteurs de l’haplotype DR11. Ces travaux ont également été reproduits pour l’haplotype HLA-DR1 et dans un modèle murin de souris transgéniques humanisées exprimant l’haplotype HLA-DR1. Les résultats de ce travail nous permettent d’envisager d’isoler des lymphocytes T CD4⁺ spécifiques d’ADAMTS13 chez les patients afin de mieux les caractériser aux différents stades de la maladie et de suivre leur évolution sous traitement dans le but de mieux anticiper les rechutes.
Thrombotic thrombocytopenic purpura (TTP) is a rare and severe disease characterized by auto-antibodies directed against ADAMTS13 (A13), a plasmatic protein involved in haemostasis. The implication of CD4⁺ T cells in the pathogenesis of the disease is suggested by the existence of a restriction to particular HLA-DR alleles and by the IgG isotype of the antibodies. In this study, we wished to determine the T cell epitopes of A13. First, we selected in silico the immunodominant peptides, based on their binding capacity to HLA-DR11 molecules. Second, their binding capacity to purified HLA-DR11 molecules using a ELISA competitive assay led us to identify the best binder peptides. Finally, we determined the peptides recognized by human CD4⁺ T cells from DR11 healthy donors and patients. These results were reproduced for the HLA-DR1 haplotype and in a transgenic humanized HLA-DR1 mouse model. In a perspective point of view, our results will allow us to further isolate the specific CD4⁺ T cells in order to characterize them at different steps of the disease and during follow-up to better anticipate relapses.
Advisors/Committee Members: Saule, Simon (thesis director), Lacroix-Desmazes, Sébastien (thesis director).
Subjects/Keywords: Épitope T; ADAMTS13; Purpura; PTT; MAT; T-Cell epitope; TTP; Purpura; ADAMTS13; TMA
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APA (6th Edition):
Gilardin, L. (2019). Identification des épitopes T d’ADAMTS13 chez les patients atteints de Purpura Thrombotique Thrombocytopénique : ADAMTS13 T cell epitope identification in ThromboticThrombocytopenic Purpura patients. (Doctoral Dissertation). Université Paris-Saclay (ComUE). Retrieved from http://www.theses.fr/2019SACLS520
Chicago Manual of Style (16th Edition):
Gilardin, Laurent. “Identification des épitopes T d’ADAMTS13 chez les patients atteints de Purpura Thrombotique Thrombocytopénique : ADAMTS13 T cell epitope identification in ThromboticThrombocytopenic Purpura patients.” 2019. Doctoral Dissertation, Université Paris-Saclay (ComUE). Accessed January 19, 2021.
http://www.theses.fr/2019SACLS520.
MLA Handbook (7th Edition):
Gilardin, Laurent. “Identification des épitopes T d’ADAMTS13 chez les patients atteints de Purpura Thrombotique Thrombocytopénique : ADAMTS13 T cell epitope identification in ThromboticThrombocytopenic Purpura patients.” 2019. Web. 19 Jan 2021.
Vancouver:
Gilardin L. Identification des épitopes T d’ADAMTS13 chez les patients atteints de Purpura Thrombotique Thrombocytopénique : ADAMTS13 T cell epitope identification in ThromboticThrombocytopenic Purpura patients. [Internet] [Doctoral dissertation]. Université Paris-Saclay (ComUE); 2019. [cited 2021 Jan 19].
Available from: http://www.theses.fr/2019SACLS520.
Council of Science Editors:
Gilardin L. Identification des épitopes T d’ADAMTS13 chez les patients atteints de Purpura Thrombotique Thrombocytopénique : ADAMTS13 T cell epitope identification in ThromboticThrombocytopenic Purpura patients. [Doctoral Dissertation]. Université Paris-Saclay (ComUE); 2019. Available from: http://www.theses.fr/2019SACLS520
University of Huddersfield
2.
Samuels, Robert.
Values of Engagement: Exploring Digital Media through Generation and Neoliberalism.
Degree: 2018, University of Huddersfield
URL: http://eprints.hud.ac.uk/id/eprint/34813/1/Samuels%20THESIS.pdf
► Within existing literature (Fiske, 1992; Jenkins, 2006; Bruns, 2007; 2008a) digital media engagement is often understood through audience productivity, privileging productive fans over unproductive others,…
(more)
▼ Within existing literature (Fiske, 1992; Jenkins, 2006; Bruns, 2007; 2008a) digital media engagement is often understood through audience productivity, privileging productive fans over unproductive others, and limiting our understanding of how and why users engage with digital media. In my study, I complicate this discourse by exploring the multi-modal value of digital engagement within an original and empirically-grounded ‘cascade’ model. Adopting a qualitative interview study, I collected in-depth interviews from 34 participants, aged 20-30, exploring my respondents’ performances of their engagement through generation and neoliberalism.
Theoretically, I argue for the plurality of value and engagement, which my participants negotiate across varying contexts (Boltanski and Thévenot, 1987/2006) through my cascade model, which aligns four original modes of engagement: fan-like, guarded, routinised, and restricted, with distinct forms of value: community, personal, habitual, and reflective. Participants enter the model via one of three levels, fluidly hybridising value and engagement in a variety of differentiated ways. Through this analysis, I argue that neoliberalism (Rose, 1999; McGuigan, 2014) emerged as a key contextual factor framing the value of participants’ engagement, with the position via which respondents enter, and thus negotiate, the cascade model relating to their specific neoliberal dispositions towards ‘right’ and ‘wrong’ ‘self-branding’ (Marwick, 2013).
By aligning participants’ neoliberal dispositions with digital cultural capital (Bourdieu, 1993; Rojas et al, 2000), I also critically interrogate the ‘digital natives’ concept (Prensky, 2001; 2012; Palfrey and Gasser, 2008), arguing that the varying levels of capital and differing engagement modes in my data challenge this monolithic discourse which assumes a shared generational digital habitus. Within my innovative model, the value of engagement is not only multi-modal, but inherently fluid, with my approach complicating discourse in this field beyond existing notions of productivity, without arguing for audience productivity as normative or positing a binary of productive and unproductive engagement. This study, therefore, is vital to furthering our understanding of how and why users engage with digital media (Light, 2014; Park, 2017; Bury,2018), and the value of this practice within neoliberal digital media ‘worlds’ (Boltanski and Thévenot, 1987/2006, p. 215).
Subjects/Keywords: H Social Sciences (General); T Technology (General)
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APA ·
Chicago ·
MLA ·
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CSE |
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Manager
APA (6th Edition):
Samuels, R. (2018). Values of Engagement: Exploring Digital Media through Generation and Neoliberalism. (Doctoral Dissertation). University of Huddersfield. Retrieved from http://eprints.hud.ac.uk/id/eprint/34813/1/Samuels%20THESIS.pdf
Chicago Manual of Style (16th Edition):
Samuels, Robert. “Values of Engagement: Exploring Digital Media through Generation and Neoliberalism.” 2018. Doctoral Dissertation, University of Huddersfield. Accessed January 19, 2021.
http://eprints.hud.ac.uk/id/eprint/34813/1/Samuels%20THESIS.pdf.
MLA Handbook (7th Edition):
Samuels, Robert. “Values of Engagement: Exploring Digital Media through Generation and Neoliberalism.” 2018. Web. 19 Jan 2021.
Vancouver:
Samuels R. Values of Engagement: Exploring Digital Media through Generation and Neoliberalism. [Internet] [Doctoral dissertation]. University of Huddersfield; 2018. [cited 2021 Jan 19].
Available from: http://eprints.hud.ac.uk/id/eprint/34813/1/Samuels%20THESIS.pdf.
Council of Science Editors:
Samuels R. Values of Engagement: Exploring Digital Media through Generation and Neoliberalism. [Doctoral Dissertation]. University of Huddersfield; 2018. Available from: http://eprints.hud.ac.uk/id/eprint/34813/1/Samuels%20THESIS.pdf
University of Huddersfield
3.
Stone, Tobias.
AN EXAMINATION OF STARTUP ACCELERATORS USING SOCIAL NETWORK THEORY.
Degree: 2018, University of Huddersfield
URL: http://eprints.hud.ac.uk/id/eprint/34731/1/Stone%20THESIS.pdf
► This thesis combines a literature review and a case study in order to examine startup accelerators as social networks. The literature review looks at two…
(more)
▼ This thesis combines a literature review and a case study in order to examine startup accelerators as social networks. The literature review looks at two distinct bodies of research; the first on Social Network Theory, in order to create a framework within which to describe an accelerator as a social network, the second on startup accelerators in order to understand their structure and evolution as business support programs. The case study uses EyeFocus Accelerator, founded by this researcher, to test some of the ideas formulated from the literature.
The literature demonstrates that accelerators are social networks, and the dynamics between the different actors in those networks can be explained and defined using the vocabulary and concepts of Social Network Theory. This describes the structure of the accelerator network, and how such a network is able to reward people with Social Capital, which is observed in this thesis to be the currency of accelerators.
Consequently, the unique nature of the research in this thesis is to describe accelerators using the language and concepts of Social Network Theory, providing new insights into how and why accelerators work.
This understanding identifies that value in accelerators lies in their ability to facilitate the flow of non-redundant information, and to provide early access to this information. Creating this value also enables accelerators to withdraw access to that value as a threat of sanction against bad actors.
Other aspects of the social network structure and behaviour of accelerators are examined, including the tendency of weak ties and non-redundancy of information to decay over time, suggesting that this may explain the typical fixed term of most accelerators.
Combined, this theory leads to an accelerator being described as a dynamic social network with a high level of closure at the core, set within a weak network architecture, with many weak ties, and consequently many bridging ties. It is policed using link reciprocity, and its currency is Social Capital. The skill used to operate in this network involves having complex role and status sets.
Subjects/Keywords: H Social Sciences (General); T Technology (General)
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APA ·
Chicago ·
MLA ·
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CSE |
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Manager
APA (6th Edition):
Stone, T. (2018). AN EXAMINATION OF STARTUP ACCELERATORS USING SOCIAL NETWORK THEORY. (Doctoral Dissertation). University of Huddersfield. Retrieved from http://eprints.hud.ac.uk/id/eprint/34731/1/Stone%20THESIS.pdf
Chicago Manual of Style (16th Edition):
Stone, Tobias. “AN EXAMINATION OF STARTUP ACCELERATORS USING SOCIAL NETWORK THEORY.” 2018. Doctoral Dissertation, University of Huddersfield. Accessed January 19, 2021.
http://eprints.hud.ac.uk/id/eprint/34731/1/Stone%20THESIS.pdf.
MLA Handbook (7th Edition):
Stone, Tobias. “AN EXAMINATION OF STARTUP ACCELERATORS USING SOCIAL NETWORK THEORY.” 2018. Web. 19 Jan 2021.
Vancouver:
Stone T. AN EXAMINATION OF STARTUP ACCELERATORS USING SOCIAL NETWORK THEORY. [Internet] [Doctoral dissertation]. University of Huddersfield; 2018. [cited 2021 Jan 19].
Available from: http://eprints.hud.ac.uk/id/eprint/34731/1/Stone%20THESIS.pdf.
Council of Science Editors:
Stone T. AN EXAMINATION OF STARTUP ACCELERATORS USING SOCIAL NETWORK THEORY. [Doctoral Dissertation]. University of Huddersfield; 2018. Available from: http://eprints.hud.ac.uk/id/eprint/34731/1/Stone%20THESIS.pdf
University of Huddersfield
4.
Kenny, Megan.
WHO’S FOLLOWING YOU? CYBER VIOLENCE ON SOCIAL MEDIA.
Degree: 2018, University of Huddersfield
URL: http://eprints.hud.ac.uk/id/eprint/34871/1/Kenny%20THESIS.pdf
► Social media use has become an integral part of daily life. Within these increasingly influential online communities, a proportion of users are subject to negative…
(more)
▼ Social media use has become an integral part of daily life. Within these increasingly influential online communities, a proportion of users are subject to negative online contact in a phenomenon labelled cyberviolence. Cyberviolence is defined as harm delivered by electronic means to a person or people who perceive this contact as negative.A review of existing literature revealed that, despite reliance on distinct offline definitions, all behaviours explored could be classified according to three key themes: sexual, threatening and humiliating cyberviolence. To assess the prevalence of these forms of cyberviolence across social media, 370 participants completed an online survey that featured items relating to victimisation and perpetration, as well as a number of well-established personality measures. These measures explored key traits and models of personality including the Big Five model to assess the potential role of an individual’s personality in their engagement in cyberviolence. The results of this thesis suggest that differences exist between those involved in cyberviolence and those who do not engage in cyberviolence on certain key personality traits including psychopathy and narcissism. Models of cybervictimisation, perpetration and a hybrid of cybervictimisation/perpetration revealed that these traits explained approximately ten percent of the variance in cyberviolence indicating that other factors, besides individual personalities, may have more influence over engagement in and/or experience of these behaviours. Overall findings suggest that there is little to demarcate those involved in cyberviolence, as victims or perpetrators, leading to the conclusion that this is not a niche area of deviance, but may be a mainstream side effect of social media use. The implications of these findings are discussed.
Subjects/Keywords: H Social Sciences (General); T Technology (General)
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APA (6th Edition):
Kenny, M. (2018). WHO’S FOLLOWING YOU? CYBER VIOLENCE ON SOCIAL MEDIA. (Thesis). University of Huddersfield. Retrieved from http://eprints.hud.ac.uk/id/eprint/34871/1/Kenny%20THESIS.pdf
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Kenny, Megan. “WHO’S FOLLOWING YOU? CYBER VIOLENCE ON SOCIAL MEDIA.” 2018. Thesis, University of Huddersfield. Accessed January 19, 2021.
http://eprints.hud.ac.uk/id/eprint/34871/1/Kenny%20THESIS.pdf.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Kenny, Megan. “WHO’S FOLLOWING YOU? CYBER VIOLENCE ON SOCIAL MEDIA.” 2018. Web. 19 Jan 2021.
Vancouver:
Kenny M. WHO’S FOLLOWING YOU? CYBER VIOLENCE ON SOCIAL MEDIA. [Internet] [Thesis]. University of Huddersfield; 2018. [cited 2021 Jan 19].
Available from: http://eprints.hud.ac.uk/id/eprint/34871/1/Kenny%20THESIS.pdf.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Kenny M. WHO’S FOLLOWING YOU? CYBER VIOLENCE ON SOCIAL MEDIA. [Thesis]. University of Huddersfield; 2018. Available from: http://eprints.hud.ac.uk/id/eprint/34871/1/Kenny%20THESIS.pdf
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
5.
Ledda, Marcelo Eduardo.
GRIDTICS – Bases para la constitución de una empresa de desarrollo de software embebido.
Degree: Instituto de Ciencias de la Administración, 2011, Universidad Católica de Córdoba
URL: http://pa.bibdigital.uccor.edu.ar/68/
► GridTICs es un grupo de investigación, desarrollo e ingeniería de proyectos relacionado a las tecnologías de información y comunicación, perteneciente a la Universidad Tecnológica Nacional…
(more)
▼ GridTICs es un grupo de investigación, desarrollo e ingeniería de proyectos relacionado a las tecnologías de información y comunicación, perteneciente a la Universidad Tecnológica Nacional Facultad Regional Mendoza. Se propone desarrollar empresarialmente su área de sistemas embebidos.
El estudio ha pretendido sentar las bases para el desarrollo de un negocio, principalmente de software, orientado al sector de sistemas embebidos.
Para la confección del trabajo se consultaron fuentes primarias como integrantes de GridTICs y actores clave en la Universidad y empresarios del negocio de software. Como complemento se examinaron textos, revistas, documentos, prensa, y principalmente, sitios de internet correspondientes a empresas y cámaras empresariales referentes del sector.
Se logró conocer que la productividad de la industria no es capaz de mantenerse al nivel de las necesidades actuales. El sector presenta un atractivo "estructural" y “transversal”, a partir de las demandas que presentan todos los sectores de la economía.
Indicadores como "Grado de aplicabilidad de los Sistemas Embebidos en cualquier ámbito sectorial" no dejan de crecer. Los Sistemas Embebidos continuarán revolucionando los sectores de energía, transporte, comunicaciones y automatización industrial y de servicios, entre otros.
En cuanto a las bases para llevar a cabo adecuadas estrategias de negocio, es necesario realizar un adecuado estudio de mercado, dado lo amplio del sector, concentrando el análisis en aquellos entornos que estén al alcance de las posibilidades y competencias, así como de infraestructura disponible.
En cuanto al tipo de trabajos a realizar se pudo observar que no es muy conveniente iniciar actividades en: desarrollo de producto, servicios orientados a aplicaciones que impliquen una alta frecuencia (eléctrica) de operación, o un complejo y costoso equipamiento, solo para la etapa de pruebas. Desde el punto de vista del tipo de cliente, no se debería abordar mercados de empresas finales, si no empresas proveedoras de soluciones embebidas.
Finalizando se observa que se presentan importantes desafíos a sortear, en materia de recursos humanos, financiamiento y habilidades de gestión empresaria en general, propios del salto estratégico planteado
Subjects/Keywords: H Ciencias Sociales (General); T Tecnología (General)
Record Details
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MLA ·
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CSE |
Export
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Manager
APA (6th Edition):
Ledda, M. E. (2011). GRIDTICS – Bases para la constitución de una empresa de desarrollo de software embebido. (Masters Thesis). Universidad Católica de Córdoba. Retrieved from http://pa.bibdigital.uccor.edu.ar/68/
Chicago Manual of Style (16th Edition):
Ledda, Marcelo Eduardo. “GRIDTICS – Bases para la constitución de una empresa de desarrollo de software embebido.” 2011. Masters Thesis, Universidad Católica de Córdoba. Accessed January 19, 2021.
http://pa.bibdigital.uccor.edu.ar/68/.
MLA Handbook (7th Edition):
Ledda, Marcelo Eduardo. “GRIDTICS – Bases para la constitución de una empresa de desarrollo de software embebido.” 2011. Web. 19 Jan 2021.
Vancouver:
Ledda ME. GRIDTICS – Bases para la constitución de una empresa de desarrollo de software embebido. [Internet] [Masters thesis]. Universidad Católica de Córdoba; 2011. [cited 2021 Jan 19].
Available from: http://pa.bibdigital.uccor.edu.ar/68/.
Council of Science Editors:
Ledda ME. GRIDTICS – Bases para la constitución de una empresa de desarrollo de software embebido. [Masters Thesis]. Universidad Católica de Córdoba; 2011. Available from: http://pa.bibdigital.uccor.edu.ar/68/
University of Huddersfield
6.
Samuels, Robert.
Values of engagement : exploring digital media through generation and neoliberalism.
Degree: PhD, 2018, University of Huddersfield
URL: http://eprints.hud.ac.uk/id/eprint/34813/
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.769062
► Within existing literature (Fiske, 1992; Jenkins, 2006; Bruns, 2007; 2008a) digital media engagement is often understood through audience productivity, privileging productive fans over unproductive others,…
(more)
▼ Within existing literature (Fiske, 1992; Jenkins, 2006; Bruns, 2007; 2008a) digital media engagement is often understood through audience productivity, privileging productive fans over unproductive others, and limiting our understanding of how and why users engage with digital media. In my study, I complicate this discourse by exploring the multi-modal value of digital engagement within an original and empirically-grounded 'cascade' model. Adopting a qualitative interview study, I collected in-depth interviews from 34 participants, aged 20-30, exploring my respondents' performances of their engagement through generation and neoliberalism. Theoretically, I argue for the plurality of value and engagement, which my participants negotiate across varying contexts (Boltanski and Thévenot, 1987/2006) through my cascade model, which aligns four original modes of engagement: fan-like, guarded, routinised, and restricted, with distinct forms of value: community, personal, habitual, and reflective. Participants enter the model via one of three levels, fluidly hybridising value and engagement in a variety of differentiated ways. Through this analysis, I argue that neoliberalism (Rose, 1999; McGuigan, 2014) emerged as a key contextual factor framing the value of participants' engagement, with the position via which respondents enter, and thus negotiate, the cascade model relating to their specific neoliberal dispositions towards 'right' and 'wrong' 'self-branding' (Marwick, 2013). By aligning participants' neoliberal dispositions with digital cultural capital (Bourdieu, 1993; Rojas et al, 2000), I also critically interrogate the 'digital natives' concept (Prensky, 2001; 2012; Palfrey and Gasser, 2008), arguing that the varying levels of capital and differing engagement modes in my data challenge this monolithic discourse which assumes a shared generational digital habitus. Within my innovative model, the value of engagement is not only multi-modal, but inherently fluid, with my approach complicating discourse in this field beyond existing notions of productivity, without arguing for audience productivity as normative or positing a binary of productive and unproductive engagement. This study, therefore, is vital to furthering our understanding of how and why users engage with digital media (Light, 2014; Park, 2017; Bury,2018), and the value of this practice within neoliberal digital media 'worlds' (Boltanski and Thévenot, 1987/2006, p. 215).
Subjects/Keywords: H Social Sciences (General); T Technology (General)
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Samuels, R. (2018). Values of engagement : exploring digital media through generation and neoliberalism. (Doctoral Dissertation). University of Huddersfield. Retrieved from http://eprints.hud.ac.uk/id/eprint/34813/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.769062
Chicago Manual of Style (16th Edition):
Samuels, Robert. “Values of engagement : exploring digital media through generation and neoliberalism.” 2018. Doctoral Dissertation, University of Huddersfield. Accessed January 19, 2021.
http://eprints.hud.ac.uk/id/eprint/34813/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.769062.
MLA Handbook (7th Edition):
Samuels, Robert. “Values of engagement : exploring digital media through generation and neoliberalism.” 2018. Web. 19 Jan 2021.
Vancouver:
Samuels R. Values of engagement : exploring digital media through generation and neoliberalism. [Internet] [Doctoral dissertation]. University of Huddersfield; 2018. [cited 2021 Jan 19].
Available from: http://eprints.hud.ac.uk/id/eprint/34813/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.769062.
Council of Science Editors:
Samuels R. Values of engagement : exploring digital media through generation and neoliberalism. [Doctoral Dissertation]. University of Huddersfield; 2018. Available from: http://eprints.hud.ac.uk/id/eprint/34813/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.769062
University of Glasgow
7.
McCallum, Claire H.
Evaluating the impact of physical activity apps and wearables : an interdisciplinary investigation of research designs and methods.
Degree: PhD, 2019, University of Glasgow
URL: http://theses.gla.ac.uk/72978/
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.775938
► Many smartphone apps and wearables have been developed to promote physical activity, however there are challenges in assessing their impact. Apps and wearables are rapidly…
(more)
▼ Many smartphone apps and wearables have been developed to promote physical activity, however there are challenges in assessing their impact. Apps and wearables are rapidly evolving technologies and thousands of physical activity apps that are publicly available on app stores remain unevaluated. There are concerns that traditional "gold standard" evaluation approaches, such as randomised control trials (RCTs), may be too slow to keep up with these, and produce effectiveness results that do not reflect real world settings. Rapid research designs (such as single case designs; SCDs) and innovative data collection methods (in-device sensors, device-generated user logs) have been proposed to improve research efficiency, yet preliminary evidence suggests they are not widely used in mHealth. This thesis reports three studies undertaken to investigate the use of rapid research designs and efficient methods for evaluating physical activity apps and wearables. First, a scoping review of the extent to which these approaches are employed by health and HCI researchers. Second, semi-structured interviews with researchers, data scientists and industry professionals to provide a deeper understanding of current evaluation practices. Third, the development and refinement of a methodological framework to support researchers in using SCDs in automated app store evaluations of physical activity apps. The findings suggest rapid research designs are not often employed in evaluations of physical activity and other health behaviour change apps. Researchers feel they face opportunity barriers (e.g. risking not being funded or published) and do not have the necessary skills (e.g. in using device generated user logs). Industry professionals appear to lack the motivation and time to evaluate effectiveness. Trade-offs were perceived between the measurement accuracy of in-device sensors and other factors such as user burden. Automated trials may speed up evaluations of physical activity apps and wearables, and the suggested data collection framework aims to support researchers in conducting rigorous effectiveness evaluations using app store- based SCDs. However, further work is needed to enable industry professionals to use the framework to evaluate their publicly-available apps.
Subjects/Keywords: H Social Sciences (General); T Technology (General)
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APA ·
Chicago ·
MLA ·
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CSE |
Export
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Manager
APA (6th Edition):
McCallum, C. H. (2019). Evaluating the impact of physical activity apps and wearables : an interdisciplinary investigation of research designs and methods. (Doctoral Dissertation). University of Glasgow. Retrieved from http://theses.gla.ac.uk/72978/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.775938
Chicago Manual of Style (16th Edition):
McCallum, Claire H. “Evaluating the impact of physical activity apps and wearables : an interdisciplinary investigation of research designs and methods.” 2019. Doctoral Dissertation, University of Glasgow. Accessed January 19, 2021.
http://theses.gla.ac.uk/72978/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.775938.
MLA Handbook (7th Edition):
McCallum, Claire H. “Evaluating the impact of physical activity apps and wearables : an interdisciplinary investigation of research designs and methods.” 2019. Web. 19 Jan 2021.
Vancouver:
McCallum CH. Evaluating the impact of physical activity apps and wearables : an interdisciplinary investigation of research designs and methods. [Internet] [Doctoral dissertation]. University of Glasgow; 2019. [cited 2021 Jan 19].
Available from: http://theses.gla.ac.uk/72978/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.775938.
Council of Science Editors:
McCallum CH. Evaluating the impact of physical activity apps and wearables : an interdisciplinary investigation of research designs and methods. [Doctoral Dissertation]. University of Glasgow; 2019. Available from: http://theses.gla.ac.uk/72978/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.775938
8.
Zeng, Qiulan.
Numerical Schemes for 1-D Two-Phase Flows.
Degree: 2017, University of Waterloo
URL: http://hdl.handle.net/10012/11890
► Modeling of two-phase flows with strong thermal and mechanical non-equilibrium ef- fects is important in engineering applications, such as the nuclear industry. The Advection Upstream…
(more)
▼ Modeling of two-phase flows with strong thermal and mechanical non-equilibrium ef-
fects is important in engineering applications, such as the nuclear industry. The Advection
Upstream Splitting Methods (AUSM-family schemes) are very popular due to their at-
tractive features for multiphase flow modeling. However, the computational efficiency of
collocated-grid-based AUSM-family schemes with explicit time integration are inferior due
to a number of issues. These include the odd-even decoupling of the collocated-grid-based
AUSM-family schemes for low-Mach-number flows, the non-conservative characteristic of
the two-phase governing equations, and the Courant-Friedrichs-Levy (CFL) number limi-
tation for the explicit time integration.
This thesis focuses on improving the accuracy and efficiency of calculation for all-Mach-
number two-phase flows. In order to achieve this objective, this thesis makes the first
attempt at using implicit staggered-grid-based AUSM-family (SG-AUSM-family) schemes.
This is a novel approach since most work in the publicly available literature solves multi-
phase compressible flow problems explicitly over collocated grids. In this thesis, a four-
equation generic two-fluid model is mainly considered. In addition, Newton’s method with
a numerical Jacobian matrix is employed to solve the implicitly discretized equations. The
benchmark test cases include Ransom’s water faucet, the oscillating manometer, the phase
separation, and the air-water shock tube problems.
In the first stage, after thorough mathematical analysis and numerical tests of various
explicit AUSM-family schemes on collocated grids, insight into the numerical dissipation
mechanism of the AUSM-family schemes was gained. This motivates the author to propose
a new scheme, namely, the staggered-grid-based AUSMFVS (SG-AUSMFVS) scheme, to
solve the stiff phase separation problem.
The second stage of the work is to examine the numerical accuracy and computational
efficiency of collocated-grid-based implicit AUSM-family schemes. Results demonstrate
that with certain time step size selections, the implicit AUSM-family schemes are superior
to their explicit counterparts, in terms of numerical accuracy and computational efficiency.
The third phase of the work is the application of the first-order SG-AUSM-family
schemes on the benchmark test cases. Results demonstrate the advantages of staggered-
grid-based AUSM + (SG-AUSM + ) and staggered-grid-based AUSMDV (SG-AUSMDV) over
their collocated-grid-based counterparts. With a staggered-grid arrangement, odd-even de-
coupling issues can be avoided. As a result, no additional diffusion terms are needed when
using SG-AUSM + and SG-AUSMDV schemes for low-Mach-number two-phase flows. Fur-
thermore, since the pressure and void fraction are already stored at the interface of the
velocity control volume, no interpolation of interfacial pressure is needed for the momen-
tum equations, thereby saving computational time. Finally, the SG-AUSM + scheme is
capable of producing accurate…
Subjects/Keywords: CFD; Multiphase flows; T-H codes; AUSM
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MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Zeng, Q. (2017). Numerical Schemes for 1-D Two-Phase Flows. (Thesis). University of Waterloo. Retrieved from http://hdl.handle.net/10012/11890
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Zeng, Qiulan. “Numerical Schemes for 1-D Two-Phase Flows.” 2017. Thesis, University of Waterloo. Accessed January 19, 2021.
http://hdl.handle.net/10012/11890.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Zeng, Qiulan. “Numerical Schemes for 1-D Two-Phase Flows.” 2017. Web. 19 Jan 2021.
Vancouver:
Zeng Q. Numerical Schemes for 1-D Two-Phase Flows. [Internet] [Thesis]. University of Waterloo; 2017. [cited 2021 Jan 19].
Available from: http://hdl.handle.net/10012/11890.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Zeng Q. Numerical Schemes for 1-D Two-Phase Flows. [Thesis]. University of Waterloo; 2017. Available from: http://hdl.handle.net/10012/11890
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Penn State University
9.
Kren, Nancy Porterfield.
Characterization of Functional Regions of OGFr.
Degree: 2015, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/26247
► The Opioid Growth Factor (OGF)-OGF receptor (OGFr) axis is present and tonically active in animal and human cancer cell lines, as well as human tumors.…
(more)
▼ The Opioid Growth Factor (OGF)-OGF receptor (OGFr) axis is present and tonically active in animal and human cancer cell lines, as well as human tumors. The OGF-OGFr pathway tonically mediates cell replication in cancer, with OGF serving as an autocrine-produced inhibitory pentapeptide. The inhibitory action of OGF on cell replication requires that OGF bind to OGFr, traffic into the nucleus to upregulate inhibitory kinases, p16 and p21 that act to stall the progression from G1-S phase of the cell cycle. Little is currently known about the functional regions required for this function.
To begin to characterize the functional regions of OGFr, mutations in OGFr identified in cancer samples were characterized. Two mutations identified in cancer samples, S378I and R444H, were characterized with respect to their effects on localization of the receptor, as well as their ability to alter DNA synthesis. R444H demonstrated a significant decrease in the nuclear/cytoplasmic ratio while S378I showed no change. Both mutations demonstrated a loss of response to OGF and the long-acting opioid receptor antagonist naltrexone (NTX) in growth assays. R444H also demonstrated a loss of inhibition in DNA synthesis, while S378I showed no significant change compared to OGFr in the BrdU assay. These data demonstrate that cancer mutations such as R444H are capable of altering the inhibitory function of OGFr, while other mutations such as S378I may be capable of altering the response to the ligand OGF or the antagonist NTX. These data contribute to the understanding of the functionally required regions of OGFr and warrant further characterization of mutations identified in cancer samples.OGFr has three nuclear localization signals (NLS) that have previously been characterized. OGFr requires at least two of the three NLSs for entry into the nucleus and for inhibition of cell proliferation. When NLSs were mutated, OGFr was excluded from the nucleus and proliferation inhibition was lost. The nuclear export of OGFr is currently unknown. In this study, endogenous OGFr, as well as exogenously expressed OGFr-EGFP, demonstrated significant nuclear accumulation in response to leptomycin B (LMB), an inhibitor of CRM1 dependent nuclear export, suggesting OGFr is exported in a CRM1 dependent manner. One leucine rich sequence fitting the consensus sequence for nuclear export signals (
NES) was identified. To better characterize this sequence, the associated leucines, L217 L220 L223 and L225, were mutated to alanine in isolation as well as in combinations. All of the mutations resulted in decreased nuclear accumulation. In support of decreased nuclear localization, subNES demonstrated a loss of inhibition. When the proposed
NES was fused to EGFP,
NES-EGFP, it responded to LMB, indicating this sequence is capable of functioning as an export signal in isolation. To investigate why the sequence functions differently in isolation than in the context of the full-length protein, the localization of subNES was evaluated in the presence of MG132, a potent inhibitor of…
Advisors/Committee Members: Patricia McLaughlin, Dissertation Advisor/Co-Advisor, Michael Verderame, Committee Member, Ira Joseph Ropson, Committee Member, Lisa M Shantz, Committee Member, Samuel Shaomin Zhang, Committee Member.
Subjects/Keywords: OGFr; NES; Tandem Repeats
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to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kren, N. P. (2015). Characterization of Functional Regions of OGFr. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/26247
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Kren, Nancy Porterfield. “Characterization of Functional Regions of OGFr.” 2015. Thesis, Penn State University. Accessed January 19, 2021.
https://submit-etda.libraries.psu.edu/catalog/26247.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Kren, Nancy Porterfield. “Characterization of Functional Regions of OGFr.” 2015. Web. 19 Jan 2021.
Vancouver:
Kren NP. Characterization of Functional Regions of OGFr. [Internet] [Thesis]. Penn State University; 2015. [cited 2021 Jan 19].
Available from: https://submit-etda.libraries.psu.edu/catalog/26247.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Kren NP. Characterization of Functional Regions of OGFr. [Thesis]. Penn State University; 2015. Available from: https://submit-etda.libraries.psu.edu/catalog/26247
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Arizona
10.
Boroson, Ethan Rain.
Optimization Under Uncertainty of Nonlinear Energy Sinks
.
Degree: 2015, University of Arizona
URL: http://hdl.handle.net/10150/595972
► Nonlinear Energy Sinks (NESs) are a promising technique for passively reducing the amplitude of vibrations. Through nonlinear stiffness properties, a NES is able to passively…
(more)
▼ Nonlinear Energy Sinks (NESs) are a promising technique for passively reducing the amplitude of vibrations. Through nonlinear stiffness properties, a
NES is able to passively absorb energy. Unlike a traditional Tuned Mass Damper (TMD), NESs do not require a specific tuning and absorb energy from a wide range of frequencies. However, each
NES is only efficient over a limited range of excitations. In addition,
NES efficiency is extremely sensitive to perturbations in design parameters or loading, demonstrating a nearly discontinuous efficiency. Therefore, in order to optimally design a
NES, uncertainties must be accounted for. This thesis focuses on optimally selecting parameters to design an effective
NES system through optimization under uncertainty. For this purpose, a specific algorithm is introduced that makes use of clustering techniques to segregate efficient and inefficient
NES behavior. SVM and Kriging approximations as well as new adaptive sampling techniques are used for the optimization under uncertainty. The variables of the problems are either random design variables or aleatory variables. For example, the excitation applied to the main vibrating system is treated as aleatory. In an effort to increase the range of excitations for which NESs are effective, a combination of NESs configured in parallel is considered. Optimization under uncertainty is performed on several examples with varying design parameters as well as different numbers of NESs (from 1 to 10). Results show that combining NESs in parallel is an effective method to increase the excitation range over which a
NES is effective.
Advisors/Committee Members: Missoum, Samy (advisor), Missoum, Samy (committeemember), Nikravesh, Parviz (committeemember), Shkarayev, Sergey (committeemember).
Subjects/Keywords: Optimization;
Uncertainty;
Mechanical Engineering;
NES
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to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Boroson, E. R. (2015). Optimization Under Uncertainty of Nonlinear Energy Sinks
. (Masters Thesis). University of Arizona. Retrieved from http://hdl.handle.net/10150/595972
Chicago Manual of Style (16th Edition):
Boroson, Ethan Rain. “Optimization Under Uncertainty of Nonlinear Energy Sinks
.” 2015. Masters Thesis, University of Arizona. Accessed January 19, 2021.
http://hdl.handle.net/10150/595972.
MLA Handbook (7th Edition):
Boroson, Ethan Rain. “Optimization Under Uncertainty of Nonlinear Energy Sinks
.” 2015. Web. 19 Jan 2021.
Vancouver:
Boroson ER. Optimization Under Uncertainty of Nonlinear Energy Sinks
. [Internet] [Masters thesis]. University of Arizona; 2015. [cited 2021 Jan 19].
Available from: http://hdl.handle.net/10150/595972.
Council of Science Editors:
Boroson ER. Optimization Under Uncertainty of Nonlinear Energy Sinks
. [Masters Thesis]. University of Arizona; 2015. Available from: http://hdl.handle.net/10150/595972
University of New Mexico
11.
Brunsing, Ryan.
Induction of interleukin-10 within the T(H)17 effector population using the GPER agonist G-1.
Degree: Biomedical Sciences Graduate Program, 2013, University of New Mexico
URL: https://digitalrepository.unm.edu/biom_etds/115
► A critical mechanism in immune homeostasis is the ability to stop an ongoing inflammatory response once the inciting agent has been destroyed or neutralized. Failure…
(more)
▼ A critical mechanism in immune homeostasis is the ability to stop an ongoing inflammatory response once the inciting agent has been destroyed or neutralized. Failure to do so can lead to autoimmune disease. One mechanism the immune system utilizes to self regulate is the secretion of immunosuppressive cytokines. For example, the cytokine interleukin-10 (IL10) is a potent suppressor of numerous key immune cell populations. Among the cells that secrete IL10 are several subsets of the CD4+
T cell family. As CD4+
T cells are commonly found within diseased tissue in the setting of autoimmune disease, medications capable of inducing IL10 expression in local CD4+
T populations would be of great therapeutic interest. The small molecule G-1, an agonist directed against the membrane-bound estrogen receptor GPER, is known to attenuate the multiple sclerosis-like animal model EAE. However, its effects on CD4+
T cell populations were previously unknown. Using cultures of purified CD4+
T cells, we show that G-1 can elicit ERK-dependent expression of IL10. G-1 treated cultures secreted 3-fold more IL10, with no change in the proinflammatory cytokines IL17A, TNFα, and IFNy. Analysis of Foxp3 and RORyt expression demonstrated increased percentages of IL10+ cells in both the TH17 (RORyt+) and Foxp3+RORyt+ hybrid
T cell compartments. We also show that, in mice, in vivo treatment with G-1 leads to increased IL10 secretion from splenocytes. These results demonstrate that G-1 acts directly on CD4+
T cells, and to our knowledge provide the first example of a synthetic small molecule capable of eliciting IL10 expression in TH17 or hybrid
T cell populations. While G-1 treatment was not effective in a murine model of colitis, investigations of its effects in other
T cell-based disease models are warranted.
Advisors/Committee Members: Prossnitz, Eric, Prossnitz, Eric, Lipscomb, Mary, Lyons, C. Rick, Hjelle, Brian.
Subjects/Keywords: GPER; G-1; CD4+ T cells; interleukin-10; T(H)17 cells
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APA ·
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MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Brunsing, R. (2013). Induction of interleukin-10 within the T(H)17 effector population using the GPER agonist G-1. (Doctoral Dissertation). University of New Mexico. Retrieved from https://digitalrepository.unm.edu/biom_etds/115
Chicago Manual of Style (16th Edition):
Brunsing, Ryan. “Induction of interleukin-10 within the T(H)17 effector population using the GPER agonist G-1.” 2013. Doctoral Dissertation, University of New Mexico. Accessed January 19, 2021.
https://digitalrepository.unm.edu/biom_etds/115.
MLA Handbook (7th Edition):
Brunsing, Ryan. “Induction of interleukin-10 within the T(H)17 effector population using the GPER agonist G-1.” 2013. Web. 19 Jan 2021.
Vancouver:
Brunsing R. Induction of interleukin-10 within the T(H)17 effector population using the GPER agonist G-1. [Internet] [Doctoral dissertation]. University of New Mexico; 2013. [cited 2021 Jan 19].
Available from: https://digitalrepository.unm.edu/biom_etds/115.
Council of Science Editors:
Brunsing R. Induction of interleukin-10 within the T(H)17 effector population using the GPER agonist G-1. [Doctoral Dissertation]. University of New Mexico; 2013. Available from: https://digitalrepository.unm.edu/biom_etds/115
University of Huddersfield
12.
Blackwell, Kane.
SOCIAL MEDIA, NEWS, AND YOUTHS: HOW YOUNG ADULTS CONSTRUCT AND ENGAGE NEWS CONTENT ON FACEBOOK.
Degree: 2018, University of Huddersfield
URL: http://eprints.hud.ac.uk/id/eprint/34820/1/Blackwell%20THESIS.pdf
► This research aims to investigate and critically assess how and to what extent young adults engage with ‘news’ on Facebook and what types of content…
(more)
▼ This research aims to investigate and critically assess how and to what extent young adults engage with ‘news’ on Facebook and what types of content they engage with. Eight young adults aged 22-30 years were interviewed along with the observation of their Facebook activity-logs over a 1-month period, from May 22nd to June 19th, during the 2017 UK general election and campaign period. The findings indicated overall that the participants used Facebook primarily as an intermediary for developing social context/understanding of news, as a means for commentary and personal expression; complementary to, prior and proceeding, their news engagement through additional media. The specifics of the participants’ Facebook engagement are outlined and discussed in detail.
Subjects/Keywords: H Social Sciences (General); JA Political science (General); T Technology (General)
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APA ·
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APA (6th Edition):
Blackwell, K. (2018). SOCIAL MEDIA, NEWS, AND YOUTHS: HOW YOUNG ADULTS CONSTRUCT AND ENGAGE NEWS CONTENT ON FACEBOOK. (Masters Thesis). University of Huddersfield. Retrieved from http://eprints.hud.ac.uk/id/eprint/34820/1/Blackwell%20THESIS.pdf
Chicago Manual of Style (16th Edition):
Blackwell, Kane. “SOCIAL MEDIA, NEWS, AND YOUTHS: HOW YOUNG ADULTS CONSTRUCT AND ENGAGE NEWS CONTENT ON FACEBOOK.” 2018. Masters Thesis, University of Huddersfield. Accessed January 19, 2021.
http://eprints.hud.ac.uk/id/eprint/34820/1/Blackwell%20THESIS.pdf.
MLA Handbook (7th Edition):
Blackwell, Kane. “SOCIAL MEDIA, NEWS, AND YOUTHS: HOW YOUNG ADULTS CONSTRUCT AND ENGAGE NEWS CONTENT ON FACEBOOK.” 2018. Web. 19 Jan 2021.
Vancouver:
Blackwell K. SOCIAL MEDIA, NEWS, AND YOUTHS: HOW YOUNG ADULTS CONSTRUCT AND ENGAGE NEWS CONTENT ON FACEBOOK. [Internet] [Masters thesis]. University of Huddersfield; 2018. [cited 2021 Jan 19].
Available from: http://eprints.hud.ac.uk/id/eprint/34820/1/Blackwell%20THESIS.pdf.
Council of Science Editors:
Blackwell K. SOCIAL MEDIA, NEWS, AND YOUTHS: HOW YOUNG ADULTS CONSTRUCT AND ENGAGE NEWS CONTENT ON FACEBOOK. [Masters Thesis]. University of Huddersfield; 2018. Available from: http://eprints.hud.ac.uk/id/eprint/34820/1/Blackwell%20THESIS.pdf
13.
Kyriakidou-Zacharoudiou, Avgousta.
Distributed development of large-scale distributed systems : the case of the particle physics grid.
Degree: PhD, 2011, London School of Economics and Political Science (University of London)
URL: http://etheses.lse.ac.uk/212/
;
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.547866
► Developing a Grid within High Energy Physics for the Large Hadron Collider particle accelerator is characterised as a highly collaborative, distributed and dynamic systems development…
(more)
▼ Developing a Grid within High Energy Physics for the Large Hadron Collider particle accelerator is characterised as a highly collaborative, distributed and dynamic systems development effort. This research examines the way this distributed Grid is developed, deployed and provided as a service to the thousands of physicists analysing data from the Large Hadron Collider. The particle physics community has always been at the forefront of computing with a tradition of working in large distributed collaborations, therefore providing a "distinctive" case of distributed systems development practice. The focus of concern is the collaborative systems development practices employed by particle physicists in their attempt to develop a usable Grid. The research aims to offer lessons and practical recommendations to those involved in globally distributed systems development and to inform the information systems development literature. Global software development presents unaddressed challenges to organisations and it is argued that there is an urgent need for new systems development practices and strategies to be created that can facilitate and embrace the rapid changes of the environment and the complexities involved in such projects. The contribution of the study, therefore, is a framework of guidance towards engendering what the author defines as "Hybrid Experimental Agile Distributed Systems Development Communities" revealing a set of dynamic collaborative practices for those organisational contexts engaged in distributed systems development. The framework will allow them to reflect on their own practice and perhaps foster a similarly dynamic flexible community in order to manage their global software development effort. The research is in the form of an interpretative qualitative exploratory case study, which draws upon Activity Theory, and frames the Grid's distributed development activity as a complex overarching networked activity system influenced by the context, the community's tools, rules, norms, culture, history, past experiences, shared visions and collaborative way of working. Tensions and contradictions throughout the development of this Grid are explored and surfaced, with the research focusing on how these are resolved in order for the activity system to achieve stability. Such stability leads to the construction of new knowledge and learning and the formation of new systems development practices. In studying this, practices are considered as an emergent property linked to improvisation, bricolage and dynamic competences that unfold as large-scale projects evolve.
Subjects/Keywords: 539.7; H Social Sciences (General) : QC Physics : T Technology (General)
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Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kyriakidou-Zacharoudiou, A. (2011). Distributed development of large-scale distributed systems : the case of the particle physics grid. (Doctoral Dissertation). London School of Economics and Political Science (University of London). Retrieved from http://etheses.lse.ac.uk/212/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.547866
Chicago Manual of Style (16th Edition):
Kyriakidou-Zacharoudiou, Avgousta. “Distributed development of large-scale distributed systems : the case of the particle physics grid.” 2011. Doctoral Dissertation, London School of Economics and Political Science (University of London). Accessed January 19, 2021.
http://etheses.lse.ac.uk/212/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.547866.
MLA Handbook (7th Edition):
Kyriakidou-Zacharoudiou, Avgousta. “Distributed development of large-scale distributed systems : the case of the particle physics grid.” 2011. Web. 19 Jan 2021.
Vancouver:
Kyriakidou-Zacharoudiou A. Distributed development of large-scale distributed systems : the case of the particle physics grid. [Internet] [Doctoral dissertation]. London School of Economics and Political Science (University of London); 2011. [cited 2021 Jan 19].
Available from: http://etheses.lse.ac.uk/212/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.547866.
Council of Science Editors:
Kyriakidou-Zacharoudiou A. Distributed development of large-scale distributed systems : the case of the particle physics grid. [Doctoral Dissertation]. London School of Economics and Political Science (University of London); 2011. Available from: http://etheses.lse.ac.uk/212/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.547866
14.
Eaton, Benjamin David.
The dynamics of digital platform innovation : unfolding the paradox of control and generativity in Apple's iOS.
Degree: PhD, 2012, London School of Economics and Political Science (University of London)
URL: http://etheses.lse.ac.uk/463/
;
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.571040
► Mobile digital platforms provide an architectural basis for third party innovation of platform complements. Platform owners have property rights, enabling them to establish a boundary…
(more)
▼ Mobile digital platforms provide an architectural basis for third party innovation of platform complements. Platform owners have property rights, enabling them to establish a boundary of permissible innovation demarcating the permitted from the prohibited. This allows for the curation of complements, which provides a means of controlling for value creation. Consequently, platform innovationthe innovation of platform complements is occasionally refused by platform owners. When this occurs tensions may arise between the two parties over where the boundary of permissible innovation should lie. Tussles may break out, embodied in complex interactions, as each party attempts to get its way. Eventually an outcome is achieved, and a platform innovation is either allowed or prohibited. A body of platform innovation literature is emerging from fields including information systems. Whilst this literature considers many aspects of platform innovation, the dynamics concerning the control of the innovation of platform innovation complements is overlooked. This research attempts to address that gap. Its relevance to information systems concerns the digitalisation of platforms as systemsdigital infrastructures, which affects their capacity for innovation and regulation. This research uses the method of narrative networks to analyse 45 examples of contested platform innovation. This approach, informed by empirical data sourced from over 4500 blog entries, identifies patterned sequences of actions across the examples. These sequences describe how tension builds, how control is asserted, and how control is then resisted. A theory of formal managerial control is used to explain how mechanisms of control are applied by platform owners as well as how developers respond to control. The principle contribution of this research is to theory. It develops and presents a theory to describe and explain the dynamics of contested innovation of complements on curated digital platforms. In doing so, iIt challenges the understanding that the platform owner alone controls platform design rules and concerning which platform complements are allowed, and which are notthe boundary of permissible innovation. Furthermore, tThe study indicates opens up the possibility that the forces of digitalisation provide third parties with the power to affect influence platform architecture, but at the cost of additional means of being controlled.
Subjects/Keywords: 621.39; H Social Sciences (General); T Technology (General)
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Eaton, B. D. (2012). The dynamics of digital platform innovation : unfolding the paradox of control and generativity in Apple's iOS. (Doctoral Dissertation). London School of Economics and Political Science (University of London). Retrieved from http://etheses.lse.ac.uk/463/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.571040
Chicago Manual of Style (16th Edition):
Eaton, Benjamin David. “The dynamics of digital platform innovation : unfolding the paradox of control and generativity in Apple's iOS.” 2012. Doctoral Dissertation, London School of Economics and Political Science (University of London). Accessed January 19, 2021.
http://etheses.lse.ac.uk/463/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.571040.
MLA Handbook (7th Edition):
Eaton, Benjamin David. “The dynamics of digital platform innovation : unfolding the paradox of control and generativity in Apple's iOS.” 2012. Web. 19 Jan 2021.
Vancouver:
Eaton BD. The dynamics of digital platform innovation : unfolding the paradox of control and generativity in Apple's iOS. [Internet] [Doctoral dissertation]. London School of Economics and Political Science (University of London); 2012. [cited 2021 Jan 19].
Available from: http://etheses.lse.ac.uk/463/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.571040.
Council of Science Editors:
Eaton BD. The dynamics of digital platform innovation : unfolding the paradox of control and generativity in Apple's iOS. [Doctoral Dissertation]. London School of Economics and Political Science (University of London); 2012. Available from: http://etheses.lse.ac.uk/463/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.571040
15.
Kenny, Megan.
Who's following you? : cyber violence on social media.
Degree: PhD, 2018, University of Huddersfield
URL: http://eprints.hud.ac.uk/id/eprint/34871/
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.777814
► Social media use has become an integral part of daily life. Within these increasingly influential online communities, a proportion of users are subject to negative…
(more)
▼ Social media use has become an integral part of daily life. Within these increasingly influential online communities, a proportion of users are subject to negative online contact in a phenomenon labelled cyberviolence. Cyberviolence is defined as harm delivered by electronic means to a person or people who perceive this contact as negative. A review of existing literature revealed that, despite reliance on distinct offline definitions, all behaviours explored could be classified according to three key themes: sexual, threatening and humiliating cyberviolence. To assess the prevalence of these forms of cyberviolence across social media, 370 participants completed an online survey that featured items relating to victimisation and perpetration, as well as a number of well-established personality measures. These measures explored key traits and models of personality including the Big Five model to assess the potential role of an individual's personality in their engagement in cyberviolence. The results of this thesis suggest that differences exist between those involved in cyberviolence and those who do not engage in cyberviolence on certain key personality traits including psychopathy and narcissism. Models of cybervictimisation, perpetration and a hybrid of cybervictimisation/perpetration revealed that these traits explained approximately ten percent of the variance in cyberviolence indicating that other factors, besides individual personalities, may have more influence over engagement in and/or experience of these behaviours. Overall findings suggest that there is little to demarcate those involved in cyberviolence, as victims or perpetrators, leading to the conclusion that this is not a niche area of deviance, but may be a mainstream side effect of social media use. The implications of these findings are discussed.
Subjects/Keywords: 610; H Social Sciences (General); T Technology (General)
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APA (6th Edition):
Kenny, M. (2018). Who's following you? : cyber violence on social media. (Doctoral Dissertation). University of Huddersfield. Retrieved from http://eprints.hud.ac.uk/id/eprint/34871/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.777814
Chicago Manual of Style (16th Edition):
Kenny, Megan. “Who's following you? : cyber violence on social media.” 2018. Doctoral Dissertation, University of Huddersfield. Accessed January 19, 2021.
http://eprints.hud.ac.uk/id/eprint/34871/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.777814.
MLA Handbook (7th Edition):
Kenny, Megan. “Who's following you? : cyber violence on social media.” 2018. Web. 19 Jan 2021.
Vancouver:
Kenny M. Who's following you? : cyber violence on social media. [Internet] [Doctoral dissertation]. University of Huddersfield; 2018. [cited 2021 Jan 19].
Available from: http://eprints.hud.ac.uk/id/eprint/34871/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.777814.
Council of Science Editors:
Kenny M. Who's following you? : cyber violence on social media. [Doctoral Dissertation]. University of Huddersfield; 2018. Available from: http://eprints.hud.ac.uk/id/eprint/34871/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.777814
University of Glasgow
16.
Sotiropoulos, Panagiotis.
HRM innovation through technology in Greece : factors influencing the adoption, diffusion and exploitation of e-HRM and social media.
Degree: PhD, 2014, University of Glasgow
URL: http://theses.gla.ac.uk/5869/
;
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637654
► Although, electronic human resources management (e-HRM) and social media technologies appear to be increasingly used by companies to design and deliver their human resources management…
(more)
▼ Although, electronic human resources management (e-HRM) and social media technologies appear to be increasingly used by companies to design and deliver their human resources management (HRM) practices in order to face the demands of knowledge based economies, there is little empirical evidence concerning whether the absorption of these technologies leads to HRM innovation. To address this gap, this thesis examines the relationships between the absorptive capacity (ACAP) of organisations, e-HRM and social media technologies, and HRM innovation. Drawing mainly on the ACAP theory when paralleled with the innovation diffusion theory, a conceptual model was created from which a range of research hypotheses were deductively developed. These hypotheses were tested by surveying a sample of two hundred large companies that operate in Greece using varied statistical techniques such as parallel analysis, exploratory factor analysis (EFA), confirmatory factor analysis (CFA), mediation analysis with bootstrapping, moderation analysis and Pearson’s correlation. To examine the reasons and the ways firms have absorbed e-HRM and social media in Greece, semi-structured interviews were conducted with the human resources (HR) directors of eight companies that had participated in the survey and had demonstrated high information communication technology (ICT) adoption. The results suggested that the ACAP of firms for e-HRM and social media has a significant effect on HRM innovation. The factors that determine ACAP and HRM innovation are: (1) the e-HRM and social media technologies, (2) the characteristics of these technologies, (3) prior knowledge and experience of firms, and (4) national culture. The adoption reasons included improvements in: data management, information security, confidentiality of data, HR service delivery, organisational culture, institutional isomorphism, and environmentally friendly e-HRM. In the case of multinational companies (MNCs): need for control by the headquarters, transparency and standardisation. Based on these findings, this thesis contributes a new framework of HRM innovation from organisational ACAP for e-HRM and social media and an alternative operationalisation of ACAP for technological knowledge around HRM. Implications for HRM, e-HRM and ACAP academics as well as HR practitioners and their companies are concluded along with the limitations of this thesis and future research suggestions.
Subjects/Keywords: 658.3009495; B Philosophy (General); H Social Sciences (General); T Technology (General)
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Sotiropoulos, P. (2014). HRM innovation through technology in Greece : factors influencing the adoption, diffusion and exploitation of e-HRM and social media. (Doctoral Dissertation). University of Glasgow. Retrieved from http://theses.gla.ac.uk/5869/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637654
Chicago Manual of Style (16th Edition):
Sotiropoulos, Panagiotis. “HRM innovation through technology in Greece : factors influencing the adoption, diffusion and exploitation of e-HRM and social media.” 2014. Doctoral Dissertation, University of Glasgow. Accessed January 19, 2021.
http://theses.gla.ac.uk/5869/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637654.
MLA Handbook (7th Edition):
Sotiropoulos, Panagiotis. “HRM innovation through technology in Greece : factors influencing the adoption, diffusion and exploitation of e-HRM and social media.” 2014. Web. 19 Jan 2021.
Vancouver:
Sotiropoulos P. HRM innovation through technology in Greece : factors influencing the adoption, diffusion and exploitation of e-HRM and social media. [Internet] [Doctoral dissertation]. University of Glasgow; 2014. [cited 2021 Jan 19].
Available from: http://theses.gla.ac.uk/5869/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637654.
Council of Science Editors:
Sotiropoulos P. HRM innovation through technology in Greece : factors influencing the adoption, diffusion and exploitation of e-HRM and social media. [Doctoral Dissertation]. University of Glasgow; 2014. Available from: http://theses.gla.ac.uk/5869/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637654
University of Glasgow
17.
Munro, Fiona Robertson.
Renewable energy in Scotland: Extending the transition-periphery dynamics approach.
Degree: PhD, 2018, University of Glasgow
URL: http://theses.gla.ac.uk/8714/
► Scotland is being transformed as renewable energy resources are being exploited through new developments and infrastructure as part of an energy transition. Scotland has a…
(more)
▼ Scotland is being transformed as renewable energy resources are being exploited through new developments and infrastructure as part of an energy transition. Scotland has a significant amount of potential onshore and offshore renewable energy available for capture largely located in rural and isolated regions. Some of this potential renewable energy has been developed and contributes to the increasing amount of energy from low carbon sources in the UK, aiding in the UK reaching its greenhouse gas (GHG) emission targets.
This thesis responds to four research questions. The first proposes an analytical framework that incorporates the concept of resource peripheries and processes of peripheralization and centralization in the multilevel perspective (MLP) from the sociotechnical transitions literature. The second discusses the transition dynamics during the renewable energy transition in Scotland that are being shaped by a number of drivers including the shift to community ownership in Scotland and a range of policies, targets, and legislation. The third address the relationship dynamics between cores and peripheries created through processes of peripheralization that include relational, multi-dimensional processes that are also multi-scalar. The fourth discusses the uneven multi-scalar dynamics created as a transition occurs with processes of peripheralization and centralization creating resource peripheries as ‘transition-periphery dynamics’. By better understanding these dynamics and relationships during transitions the renewable energy transition can be better informed to deal with possible implications and ensure possible benefits are secured for a more sustainable future.
Subjects/Keywords: G Geography (General); H Social Sciences (General); T Technology (General)
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
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Manager
APA (6th Edition):
Munro, F. R. (2018). Renewable energy in Scotland: Extending the transition-periphery dynamics approach. (Doctoral Dissertation). University of Glasgow. Retrieved from http://theses.gla.ac.uk/8714/
Chicago Manual of Style (16th Edition):
Munro, Fiona Robertson. “Renewable energy in Scotland: Extending the transition-periphery dynamics approach.” 2018. Doctoral Dissertation, University of Glasgow. Accessed January 19, 2021.
http://theses.gla.ac.uk/8714/.
MLA Handbook (7th Edition):
Munro, Fiona Robertson. “Renewable energy in Scotland: Extending the transition-periphery dynamics approach.” 2018. Web. 19 Jan 2021.
Vancouver:
Munro FR. Renewable energy in Scotland: Extending the transition-periphery dynamics approach. [Internet] [Doctoral dissertation]. University of Glasgow; 2018. [cited 2021 Jan 19].
Available from: http://theses.gla.ac.uk/8714/.
Council of Science Editors:
Munro FR. Renewable energy in Scotland: Extending the transition-periphery dynamics approach. [Doctoral Dissertation]. University of Glasgow; 2018. Available from: http://theses.gla.ac.uk/8714/
University of Glasgow
18.
Sotiropoulos, Panagiotis.
HRΜ innovation through technology in Greece: factors influencing the adoption, diffusion and exploitation of e-HRM and social media.
Degree: PhD, 2014, University of Glasgow
URL: http://theses.gla.ac.uk/5869/
► Although, electronic human resources management (e-HRM) and social media technologies appear to be increasingly used by companies to design and deliver their human resources management…
(more)
▼ Although, electronic human resources management (e-HRM) and social media technologies appear to be increasingly used by companies to design and deliver their human resources management (HRM) practices in order to face the demands of knowledge based economies, there is little empirical evidence concerning whether the absorption of these technologies leads to HRM innovation. To address this gap, this thesis examines the relationships between the absorptive capacity (ACAP) of organisations, e-HRM and social media technologies, and HRM innovation. Drawing mainly on the ACAP theory when paralleled with the innovation diffusion theory, a conceptual model was created from which a range of research hypotheses were deductively developed. These hypotheses were tested by surveying a sample of two hundred large companies that operate in Greece using varied statistical techniques such as parallel analysis, exploratory factor analysis (EFA), confirmatory factor analysis (CFA), mediation analysis with bootstrapping, moderation analysis and Pearson’s correlation. To examine the reasons and the ways firms have absorbed e-HRM and social media in Greece, semi-structured interviews were conducted with the human resources (HR) directors of eight companies that had participated in the survey and had demonstrated high information communication technology (ICT) adoption. The results suggested that the ACAP of firms for e-HRM and social media has a significant effect on HRM innovation. The factors that determine ACAP and HRM innovation are: (1) the e-HRM and social media technologies, (2) the characteristics of these technologies, (3) prior knowledge and experience of firms, and (4) national culture. The adoption reasons included improvements in: data management, information security, confidentiality of data, HR service delivery, organisational culture, institutional isomorphism, and environmentally friendly e-HRM. In the case of multinational companies (MNCs): need for control by the headquarters, transparency and standardisation. Based on these findings, this thesis contributes a new framework of HRM innovation from organisational ACAP for e-HRM and social media and an alternative operationalisation of ACAP for technological knowledge around HRM. Implications for HRM, e-HRM and ACAP academics as well as HR practitioners and their companies are concluded along with the limitations of this thesis and future research suggestions.
Subjects/Keywords: B Philosophy (General); H Social Sciences (General); T Technology (General)
Record Details
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Record Details
Similar Records
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« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Sotiropoulos, P. (2014). HRΜ innovation through technology in Greece: factors influencing the adoption, diffusion and exploitation of e-HRM and social media. (Doctoral Dissertation). University of Glasgow. Retrieved from http://theses.gla.ac.uk/5869/
Chicago Manual of Style (16th Edition):
Sotiropoulos, Panagiotis. “HRΜ innovation through technology in Greece: factors influencing the adoption, diffusion and exploitation of e-HRM and social media.” 2014. Doctoral Dissertation, University of Glasgow. Accessed January 19, 2021.
http://theses.gla.ac.uk/5869/.
MLA Handbook (7th Edition):
Sotiropoulos, Panagiotis. “HRΜ innovation through technology in Greece: factors influencing the adoption, diffusion and exploitation of e-HRM and social media.” 2014. Web. 19 Jan 2021.
Vancouver:
Sotiropoulos P. HRΜ innovation through technology in Greece: factors influencing the adoption, diffusion and exploitation of e-HRM and social media. [Internet] [Doctoral dissertation]. University of Glasgow; 2014. [cited 2021 Jan 19].
Available from: http://theses.gla.ac.uk/5869/.
Council of Science Editors:
Sotiropoulos P. HRΜ innovation through technology in Greece: factors influencing the adoption, diffusion and exploitation of e-HRM and social media. [Doctoral Dissertation]. University of Glasgow; 2014. Available from: http://theses.gla.ac.uk/5869/
The London School of Economics and Political Science (LSE)
19.
Kyriakidou-Zacharoudiou, Avgousta.
Distributed development of large-scale distributed systems: the case of the particle physics grid.
Degree: phd, 2011, The London School of Economics and Political Science (LSE)
URL: http://etheses.lse.ac.uk/212/
► Developing a Grid within High Energy Physics for the Large Hadron Collider particle accelerator is characterised as a highly collaborative, distributed and dynamic systems development…
(more)
▼ Developing a Grid within High Energy Physics for the Large Hadron Collider particle accelerator is characterised as a highly collaborative, distributed and dynamic systems development effort. This research examines the way this distributed Grid is developed, deployed and provided as a service to the thousands of physicists analysing data from the Large Hadron Collider. The particle physics community has always been at the forefront of computing with a tradition of working in large distributed collaborations, therefore providing a "distinctive" case of distributed systems development practice. The focus of concern is the collaborative systems development practices employed by particle physicists in their attempt to develop a usable Grid.
The research aims to offer lessons and practical recommendations to those involved in globally distributed systems development and to inform the information systems development literature. Global software development presents unaddressed challenges to organisations and it is argued that there is an urgent need for new systems development practices and strategies to be created that can facilitate and embrace the rapid changes of the environment and the complexities involved in such projects. The contribution of the study, therefore, is a framework of guidance towards engendering what the author defines as "Hybrid Experimental Agile Distributed Systems Development Communities" revealing a set of dynamic collaborative practices for those organisational contexts engaged in distributed systems development. The framework will allow them to reflect on their own practice and perhaps foster a similarly dynamic flexible community in order to manage their global software development effort.
The research is in the form of an interpretative qualitative exploratory case study, which draws upon Activity Theory, and frames the Grid's distributed development activity as a complex overarching networked activity system influenced by the context, the community's tools, rules, norms, culture, history, past experiences, shared visions and collaborative way of working. Tensions and contradictions throughout the development of this Grid are explored and surfaced, with the research focusing on how these are resolved in order for the activity system to achieve stability. Such stability leads to the construction of new knowledge and learning and the formation of new systems development practices. In studying this, practices are considered as an emergent property linked to improvisation, bricolage and dynamic competences that unfold as large-scale projects evolve.
Subjects/Keywords: H Social Sciences (General); QC Physics; T Technology (General)
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kyriakidou-Zacharoudiou, A. (2011). Distributed development of large-scale distributed systems: the case of the particle physics grid. (Doctoral Dissertation). The London School of Economics and Political Science (LSE). Retrieved from http://etheses.lse.ac.uk/212/
Chicago Manual of Style (16th Edition):
Kyriakidou-Zacharoudiou, Avgousta. “Distributed development of large-scale distributed systems: the case of the particle physics grid.” 2011. Doctoral Dissertation, The London School of Economics and Political Science (LSE). Accessed January 19, 2021.
http://etheses.lse.ac.uk/212/.
MLA Handbook (7th Edition):
Kyriakidou-Zacharoudiou, Avgousta. “Distributed development of large-scale distributed systems: the case of the particle physics grid.” 2011. Web. 19 Jan 2021.
Vancouver:
Kyriakidou-Zacharoudiou A. Distributed development of large-scale distributed systems: the case of the particle physics grid. [Internet] [Doctoral dissertation]. The London School of Economics and Political Science (LSE); 2011. [cited 2021 Jan 19].
Available from: http://etheses.lse.ac.uk/212/.
Council of Science Editors:
Kyriakidou-Zacharoudiou A. Distributed development of large-scale distributed systems: the case of the particle physics grid. [Doctoral Dissertation]. The London School of Economics and Political Science (LSE); 2011. Available from: http://etheses.lse.ac.uk/212/
The London School of Economics and Political Science (LSE)
20.
Kaparoglu, Zeynep.
Matchmakers or tastemakers? Platformization of cultural intermediation & social media’s engines for ‘making up taste’.
Degree: phd, 2018, The London School of Economics and Political Science (LSE)
URL: http://etheses.lse.ac.uk/4194/
► There are long-standing practices and processes that have traditionally mediated between the processes of production and consumption of cultural content. The prominent instances of these…
(more)
▼ There are long-standing practices and processes that have traditionally mediated between the processes of production and consumption of cultural content. The prominent instances of these are: curating content by identifying and selecting cultural content in order to promote to a particular set of audiences; measuring audience behaviours to construct knowledge about their tastes; and guiding audiences through recommendations from cultural experts. These cultural intermediation processes are currently being transformed, and social media platforms play important roles in this transformation. However, their role is often attributed to the work of users and/or recommendation algorithms. Thus, the processes through which data about users’ taste are aggregated and made ready for algorithmic processing are largely neglected. This study takes this problematic as an important gap in our understanding of social media platforms’ role in the transformation of cultural intermediation. To address this gap, the notion of platformization is used as a theoretical lens to examine the role of users and algorithms as part of social media’s distinct data-based sociotechnical configuration, which is built on the so-called ‘platform-logic’. Based on a set of conceptual ideas and the findings derived through a single case study on a music discovery platform, this thesis developed a framework to explain ‘platformization of cultural intermediation’. This framework outlines how curation, guidance, and measurement processes are ‘plat-formed’ in the course of development and optimisation of a social media platform. This is the main contribution of the thesis. The study also contributes to the literature by developing the concept of social media’s engines for ‘making up taste’. This concept illuminates how social media operate as sociotechnical cultural intermediaries and participates in tastemaking in ways that acquire legitimacy from the long-standing trust in the objectivity of classification, quantification, and measurement processes.
Subjects/Keywords: H Social Sciences (General); T Technology (General); ZA4450 Databases
Record Details
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Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kaparoglu, Z. (2018). Matchmakers or tastemakers? Platformization of cultural intermediation & social media’s engines for ‘making up taste’. (Doctoral Dissertation). The London School of Economics and Political Science (LSE). Retrieved from http://etheses.lse.ac.uk/4194/
Chicago Manual of Style (16th Edition):
Kaparoglu, Zeynep. “Matchmakers or tastemakers? Platformization of cultural intermediation & social media’s engines for ‘making up taste’.” 2018. Doctoral Dissertation, The London School of Economics and Political Science (LSE). Accessed January 19, 2021.
http://etheses.lse.ac.uk/4194/.
MLA Handbook (7th Edition):
Kaparoglu, Zeynep. “Matchmakers or tastemakers? Platformization of cultural intermediation & social media’s engines for ‘making up taste’.” 2018. Web. 19 Jan 2021.
Vancouver:
Kaparoglu Z. Matchmakers or tastemakers? Platformization of cultural intermediation & social media’s engines for ‘making up taste’. [Internet] [Doctoral dissertation]. The London School of Economics and Political Science (LSE); 2018. [cited 2021 Jan 19].
Available from: http://etheses.lse.ac.uk/4194/.
Council of Science Editors:
Kaparoglu Z. Matchmakers or tastemakers? Platformization of cultural intermediation & social media’s engines for ‘making up taste’. [Doctoral Dissertation]. The London School of Economics and Political Science (LSE); 2018. Available from: http://etheses.lse.ac.uk/4194/
University of Huddersfield
21.
Stone, Tobias.
An examination of startup accelerators using social network theory.
Degree: PhD, 2018, University of Huddersfield
URL: http://eprints.hud.ac.uk/id/eprint/34731/
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.762032
► This thesis combines a literature review and a case study in order to examine startup accelerators as social networks. The literature review looks at two…
(more)
▼ This thesis combines a literature review and a case study in order to examine startup accelerators as social networks. The literature review looks at two distinct bodies of research; the first on Social Network Theory, in order to create a framework within which to describe an accelerator as a social network, the second on startup accelerators in order to understand their structure and evolution as business support programs. The case study uses EyeFocus Accelerator, founded by this researcher, to test some of the ideas formulated from the literature. The literature demonstrates that accelerators are social networks, and the dynamics between the different actors in those networks can be explained and defined using the vocabulary and concepts of Social Network Theory. This describes the structure of the accelerator network, and how such a network is able to reward people with Social Capital, which is observed in this thesis to be the currency of accelerators. Consequently, the unique nature of the research in this thesis is to describe accelerators using the language and concepts of Social Network Theory, providing new insights into how and why accelerators work. This understanding identifies that value in accelerators lies in their ability to facilitate the flow of non-redundant information, and to provide early access to this information. Creating this value also enables accelerators to withdraw access to that value as a threat of sanction against bad actors. Other aspects of the social network structure and behaviour of accelerators are examined, including the tendency of weak ties and non-redundancy of information to decay over time, suggesting that this may explain the typical fixed term of most accelerators. Combined, this theory leads to an accelerator being described as a dynamic social network with a high level of closure at the core, set within a weak network architecture, with many weak ties, and consequently many bridging ties. It is policed using link reciprocity, and its currency is Social Capital. The skill used to operate in this network involves having complex role and status sets.
Subjects/Keywords: 302.3; H Social Sciences (General); T Technology (General)
Record Details
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Stone, T. (2018). An examination of startup accelerators using social network theory. (Doctoral Dissertation). University of Huddersfield. Retrieved from http://eprints.hud.ac.uk/id/eprint/34731/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.762032
Chicago Manual of Style (16th Edition):
Stone, Tobias. “An examination of startup accelerators using social network theory.” 2018. Doctoral Dissertation, University of Huddersfield. Accessed January 19, 2021.
http://eprints.hud.ac.uk/id/eprint/34731/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.762032.
MLA Handbook (7th Edition):
Stone, Tobias. “An examination of startup accelerators using social network theory.” 2018. Web. 19 Jan 2021.
Vancouver:
Stone T. An examination of startup accelerators using social network theory. [Internet] [Doctoral dissertation]. University of Huddersfield; 2018. [cited 2021 Jan 19].
Available from: http://eprints.hud.ac.uk/id/eprint/34731/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.762032.
Council of Science Editors:
Stone T. An examination of startup accelerators using social network theory. [Doctoral Dissertation]. University of Huddersfield; 2018. Available from: http://eprints.hud.ac.uk/id/eprint/34731/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.762032
22.
Kaparoglu, Zeynep.
Matchmakers or tastemakers? : platformization of cultural intermediation & social media's engines for 'making up taste'.
Degree: PhD, 2018, London School of Economics and Political Science (University of London)
URL: http://etheses.lse.ac.uk/4194/
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.819636
► There are long-standing practices and processes that have traditionally mediated between the processes of production and consumption of cultural content. The prominent instances of these…
(more)
▼ There are long-standing practices and processes that have traditionally mediated between the processes of production and consumption of cultural content. The prominent instances of these are: curating content by identifying and selecting cultural content in order to promote to a particular set of audiences; measuring audience behaviours to construct knowledge about their tastes; and guiding audiences through recommendations from cultural experts. These cultural intermediation processes are currently being transformed, and social media platforms play important roles in this transformation. However, their role is often attributed to the work of users and/or recommendation algorithms. Thus, the processes through which data about users’ taste are aggregated and made ready for algorithmic processing are largely neglected. This study takes this problematic as an important gap in our understanding of social media platforms’ role in the transformation of cultural intermediation. To address this gap, the notion of platformization is used as a theoretical lens to examine the role of users and algorithms as part of social media’s distinct data-based sociotechnical configuration, which is built on the so-called ‘platform-logic’. Based on a set of conceptual ideas and the findings derived through a single case study on a music discovery platform, this thesis developed a framework to explain ‘platformization of cultural intermediation’. This framework outlines how curation, guidance, and measurement processes are ‘plat-formed’ in the course of development and optimisation of a social media platform. This is the main contribution of the thesis. The study also contributes to the literature by developing the concept of social media’s engines for ‘making up taste’. This concept illuminates how social media operate as sociotechnical cultural intermediaries and participates in tastemaking in ways that acquire legitimacy from the long-standing trust in the objectivity of classification, quantification, and measurement processes.
Subjects/Keywords: H Social Sciences (General); T Technology (General); ZA4450 Databases
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kaparoglu, Z. (2018). Matchmakers or tastemakers? : platformization of cultural intermediation & social media's engines for 'making up taste'. (Doctoral Dissertation). London School of Economics and Political Science (University of London). Retrieved from http://etheses.lse.ac.uk/4194/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.819636
Chicago Manual of Style (16th Edition):
Kaparoglu, Zeynep. “Matchmakers or tastemakers? : platformization of cultural intermediation & social media's engines for 'making up taste'.” 2018. Doctoral Dissertation, London School of Economics and Political Science (University of London). Accessed January 19, 2021.
http://etheses.lse.ac.uk/4194/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.819636.
MLA Handbook (7th Edition):
Kaparoglu, Zeynep. “Matchmakers or tastemakers? : platformization of cultural intermediation & social media's engines for 'making up taste'.” 2018. Web. 19 Jan 2021.
Vancouver:
Kaparoglu Z. Matchmakers or tastemakers? : platformization of cultural intermediation & social media's engines for 'making up taste'. [Internet] [Doctoral dissertation]. London School of Economics and Political Science (University of London); 2018. [cited 2021 Jan 19].
Available from: http://etheses.lse.ac.uk/4194/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.819636.
Council of Science Editors:
Kaparoglu Z. Matchmakers or tastemakers? : platformization of cultural intermediation & social media's engines for 'making up taste'. [Doctoral Dissertation]. London School of Economics and Political Science (University of London); 2018. Available from: http://etheses.lse.ac.uk/4194/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.819636
University of Birmingham
23.
Alsaif, Mohammed.
Factors affecting citizens' adoption of e-government moderated by socio-cultural values in Saudi Arabia.
Degree: PhD, 2014, University of Birmingham
URL: http://etheses.bham.ac.uk//id/eprint/4851/
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.600275
► This study aims to consider the problems associated with the low response of citizens to the adoption of e-government in developing Arab countries, with a…
(more)
▼ This study aims to consider the problems associated with the low response of citizens to the adoption of e-government in developing Arab countries, with a predominant focus on the Kingdom of Saudi Arabia. The study has validated the UTAUT in Saudi Arabia and has extend the theory by including further variable such as the trust, compatibility, awareness and the service quality which proposed to influence citizens adoption of e-government in Saudi Arabia. As the adoption consider as an efficient method to evaluate the success of the implementation. It is necessary for this new innovation to be tailored to citizens’ wishes, and taking into account the religious, cultural, traditional and other beliefs to ensure the widespread adoption of this innovation. The finding reveals that performance expectancy is the strong predictor of the intention to use e-government followed by the trust of the internet. On the other hand, intention to use behaviour, computer self-efficacy and availability of resources found to be significant predictors of the usage behaviour.
Subjects/Keywords: 352.3; H Social Sciences (General); T Technology (General)
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MLA ·
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APA (6th Edition):
Alsaif, M. (2014). Factors affecting citizens' adoption of e-government moderated by socio-cultural values in Saudi Arabia. (Doctoral Dissertation). University of Birmingham. Retrieved from http://etheses.bham.ac.uk//id/eprint/4851/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.600275
Chicago Manual of Style (16th Edition):
Alsaif, Mohammed. “Factors affecting citizens' adoption of e-government moderated by socio-cultural values in Saudi Arabia.” 2014. Doctoral Dissertation, University of Birmingham. Accessed January 19, 2021.
http://etheses.bham.ac.uk//id/eprint/4851/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.600275.
MLA Handbook (7th Edition):
Alsaif, Mohammed. “Factors affecting citizens' adoption of e-government moderated by socio-cultural values in Saudi Arabia.” 2014. Web. 19 Jan 2021.
Vancouver:
Alsaif M. Factors affecting citizens' adoption of e-government moderated by socio-cultural values in Saudi Arabia. [Internet] [Doctoral dissertation]. University of Birmingham; 2014. [cited 2021 Jan 19].
Available from: http://etheses.bham.ac.uk//id/eprint/4851/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.600275.
Council of Science Editors:
Alsaif M. Factors affecting citizens' adoption of e-government moderated by socio-cultural values in Saudi Arabia. [Doctoral Dissertation]. University of Birmingham; 2014. Available from: http://etheses.bham.ac.uk//id/eprint/4851/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.600275
24.
Martin, Sam C.
Coeliac disease : chronic illness and self-care in the digital age.
Degree: PhD, 2017, University of Warwick
URL: http://wrap.warwick.ac.uk/103497/
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.752432
► This doctoral research contributes to three main fields: the Sociology of Health and Illness (SHI), specifically in the way it speaks to Coeliac Disease; and…
(more)
▼ This doctoral research contributes to three main fields: the Sociology of Health and Illness (SHI), specifically in the way it speaks to Coeliac Disease; and the field of Big Social Data and Health in general. Research in SHI, has typically focussed on the effects of diagnosis on self-identity, and illness narratives used in adapting to life with chronic disease. While there have been recent studies looking at how general food cultures, obesity and diabetes are visualised on social media, there have been no studies about the visualisation of self-care and identity in relation to Coeliac Disease specifically. Current social research in Coeliac Disease is mainly focused on the psychological impact of being diagnosed with Coeliac Disease and the challenge the gluten free diet can put on individuals. There is little in the literature about how individuals self-manage Coeliac Disease or share identity across social media platforms, or how they use social media to navigate risk. Current literature in the field of Big Social Data and Health, mainly looks at how social media offers opportunities to socially share or disseminate public health information between organisations and the public, as well as how the use of wearable technology and apps are used to quantify health. It does not look at how the chronically ill share symptoms, identity and self-care across social media platforms. This thesis adds to the literature by bringing together the fields of SHI, Big Social Data and Health, and Social Science research into Coeliac Disease to understand and visualise the way Coeliac patients actively use social media platforms in the process of self-care and self-identity. It explores how social media can be used to tell a chronic illness narrative, and thus illustrate the process of diagnosis, and how individuals adapt to life as a Coeliac on the gluten free diet (GFD). In doing so, this research provides an illustrative example of how social media data can be used to both inform and complement research on Coeliac Disease specifically, and the fields of SHI and digital social science more generally.
Subjects/Keywords: 362.1963; H Social Sciences (General); HM Sociology; T Technology (General)
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Martin, S. C. (2017). Coeliac disease : chronic illness and self-care in the digital age. (Doctoral Dissertation). University of Warwick. Retrieved from http://wrap.warwick.ac.uk/103497/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.752432
Chicago Manual of Style (16th Edition):
Martin, Sam C. “Coeliac disease : chronic illness and self-care in the digital age.” 2017. Doctoral Dissertation, University of Warwick. Accessed January 19, 2021.
http://wrap.warwick.ac.uk/103497/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.752432.
MLA Handbook (7th Edition):
Martin, Sam C. “Coeliac disease : chronic illness and self-care in the digital age.” 2017. Web. 19 Jan 2021.
Vancouver:
Martin SC. Coeliac disease : chronic illness and self-care in the digital age. [Internet] [Doctoral dissertation]. University of Warwick; 2017. [cited 2021 Jan 19].
Available from: http://wrap.warwick.ac.uk/103497/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.752432.
Council of Science Editors:
Martin SC. Coeliac disease : chronic illness and self-care in the digital age. [Doctoral Dissertation]. University of Warwick; 2017. Available from: http://wrap.warwick.ac.uk/103497/ ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.752432
25.
Paul, David.
Geometrical Locating Scheme for Complex Hybrid Manufacturing: Multiple Additive Manufacturing and Machining
.
Degree: Chalmers tekniska högskola / Institutionen för industri- och materialvetenskap, 2019, Chalmers University of Technology
URL: http://hdl.handle.net/20.500.12380/300358
► The technology of additive manufacturing is rapidly developing as one of the most sustainable alternatives for the traditional manufacturing processes. Additive manufacturing technologies offer numerous…
(more)
▼ The technology of additive manufacturing is rapidly developing as one of the most
sustainable alternatives for the traditional manufacturing processes. Additive manufacturing
technologies offer numerous advantages such as weight reduction, design
freedom, reducing material waste and so on. But to manufacture complex components,
the traditional manufacturing processes are still needed to obtain the final
desired geometry.
DiSAM is one such project that is happening in Sweden, aiming to improve the
technology readiness of additive manufacturing processes. A complex aircraft component
is being manufactured in this project using both additive manufacturing
and traditional manufacturing processes. In this process of complex manufacturing
where, multiple additive manufacturing processes and machining processes are involved,
the effect of the locating scheme in each step of manufacturing process plays
a vital role in providing the desired geometrical accuracy.
This thesis work was carried out to develop a locating scheme that was most suitable
to follow in this complex manufacturing process chain. The component from the
engine exit structure of a gas turbine engine which is termed as "H-Sector" was the
product in focus.
Information was collected through interviews with the stakeholders of the DiSAM
project. The manufacturing process flow was studied to finalize on the parameters
that affects the geometrical accuracy at different manufacturing steps. The critical
areas of the components were identified which needs to be focused in developing
locating scheme at each manufacturing step.
The software RD&T was used in evaluating the locating schemes. Different locating
scheme strategies were developed. Sensitivity analysis was carried out to compare
between the strategies and finalizing on the final locating scheme.
This thesis outcome will help in making decisions regarding the locating scheme
for the DiSAM project. The same method can be followed in developing different
locating scheme for different geometry in the future.
Subjects/Keywords: H-sector; locating scheme; SLM; LMD; machining; RD&T
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Paul, D. (2019). Geometrical Locating Scheme for Complex Hybrid Manufacturing: Multiple Additive Manufacturing and Machining
. (Thesis). Chalmers University of Technology. Retrieved from http://hdl.handle.net/20.500.12380/300358
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Paul, David. “Geometrical Locating Scheme for Complex Hybrid Manufacturing: Multiple Additive Manufacturing and Machining
.” 2019. Thesis, Chalmers University of Technology. Accessed January 19, 2021.
http://hdl.handle.net/20.500.12380/300358.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Paul, David. “Geometrical Locating Scheme for Complex Hybrid Manufacturing: Multiple Additive Manufacturing and Machining
.” 2019. Web. 19 Jan 2021.
Vancouver:
Paul D. Geometrical Locating Scheme for Complex Hybrid Manufacturing: Multiple Additive Manufacturing and Machining
. [Internet] [Thesis]. Chalmers University of Technology; 2019. [cited 2021 Jan 19].
Available from: http://hdl.handle.net/20.500.12380/300358.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Paul D. Geometrical Locating Scheme for Complex Hybrid Manufacturing: Multiple Additive Manufacturing and Machining
. [Thesis]. Chalmers University of Technology; 2019. Available from: http://hdl.handle.net/20.500.12380/300358
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
26.
Brito, Rafaela Rodrigues de [UNESP].
Imobilização de lipase com atividade de transesterificação produzida pelo novo isolado Acremonium-like rog 2.1.9 em matrizes a base de resíduos agroindustriais e aplicação na produção de biodiesel.
Degree: 2017, Universidade Estadual Paulista
URL: http://hdl.handle.net/11449/148890
► As lipases apresentam atividades catalíticas específicas as quais permitem seu uso em diferentes setores da indústria, como de alimentos, tratamento de águas residuais, cosméticos, farmacêuticos…
(more)
▼ As lipases apresentam atividades catalíticas específicas as quais permitem seu uso em diferentes setores da indústria, como de alimentos, tratamento de águas residuais, cosméticos, farmacêuticos e biocombutíveis. A imobilização dessas enzimas torna mais eficiente sua aplicação uma vez que preserva suas propriedades bioquímicas nas condições reacionais e facilita recuperação e reutilização. O objetivo deste trabalho foi caracterizar a lipase bruta produzida pelo fungo Acremonium-like
ROG 2.1.9, purificá-la parcialmente e imobilizá-la em diferentes matrizes, incluindo resíduos agro-industriais, e sua utilização na produção de biodiesel por transesterificação enzimática. A enzima apresentou maior atividade a pH 7,0 e a 45°C e estabilidade na presença de n-hexano e metanol, com 92% e 40% de atividade residual, respectivamente, após 24 horas em presença daqueles compostos. A lipase mostrou ainda, especificidade por ácidos graxos de cadeia média como p-nitrofenil decanoato (C10:0), seguido de p-nitrofenil palmitato (C16:0). A enzima foi purificada parcialmente por precipitação fracionada com sulfato de amônio, com maior rendimento obtido na faixa entre 30-50% de saturação do sal. Após ser parcialmente purificada, a lipase foi imobilizada por adsorção em bagaço de cana e sabugo de milho não ativados, por meio de interação hidrofóbica em Sepabeads C18, Lewatit 105 e Lewatit 1600, por interação iônica em PEI-agarose, MANAE-sabugo de milho e MANAE-bagaço de cana e por ligação covalente multipontual em Glioxil-sabugo de milho e Glioxil-bagaço de cana. As imobilizações por interação iônica apresentaram os maiores rendimentos, com aumento de 100% na atividade da enzima imobilizada em MANAE-sabugo e os derivados gerados a partir destes suportes foram selecionados para os trabalhos seguintes. O derivado Lip-MANAE-sabugo apresentou maior força de interação iônica (a enzima não se dissociou da matriz), Lip-MANAE-bagaço foi o mais estável termicamente (45°C) e o derivado Lip-PEI-agarose foi o mais estável em etanol (30% v/v). A atividade da lipase imobilizada em MANAE-sabugo e MANAE-bagaço aumentou na presença de etanol, n-hexano e DMSO, e na presença dos surfactantes CTAB e Triton x-100. Com base nos resultados, pode-se concluir que o uso dos resíduos agro-industriais (bagaço de cana e sabugo de milho) como suporte, após serem ativados com grupos amino, é uma alternativa eficaz e de baixo custo para aplicação de lipases imobilizadas.
Advisors/Committee Members: Gomes, Eleni [UNESP], Universidade Estadual Paulista (UNESP).
Subjects/Keywords: Biodiesel; Imobilização; Transesterificação enzimática; Biocatálise; Acremonium-like ROG 2.1.9
Record Details
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APA ·
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MLA ·
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Export
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Manager
APA (6th Edition):
Brito, R. R. d. [. (2017). Imobilização de lipase com atividade de transesterificação produzida pelo novo isolado Acremonium-like rog 2.1.9 em matrizes a base de resíduos agroindustriais e aplicação na produção de biodiesel. (Thesis). Universidade Estadual Paulista. Retrieved from http://hdl.handle.net/11449/148890
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Brito, Rafaela Rodrigues de [UNESP]. “Imobilização de lipase com atividade de transesterificação produzida pelo novo isolado Acremonium-like rog 2.1.9 em matrizes a base de resíduos agroindustriais e aplicação na produção de biodiesel.” 2017. Thesis, Universidade Estadual Paulista. Accessed January 19, 2021.
http://hdl.handle.net/11449/148890.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Brito, Rafaela Rodrigues de [UNESP]. “Imobilização de lipase com atividade de transesterificação produzida pelo novo isolado Acremonium-like rog 2.1.9 em matrizes a base de resíduos agroindustriais e aplicação na produção de biodiesel.” 2017. Web. 19 Jan 2021.
Vancouver:
Brito RRd[. Imobilização de lipase com atividade de transesterificação produzida pelo novo isolado Acremonium-like rog 2.1.9 em matrizes a base de resíduos agroindustriais e aplicação na produção de biodiesel. [Internet] [Thesis]. Universidade Estadual Paulista; 2017. [cited 2021 Jan 19].
Available from: http://hdl.handle.net/11449/148890.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Brito RRd[. Imobilização de lipase com atividade de transesterificação produzida pelo novo isolado Acremonium-like rog 2.1.9 em matrizes a base de resíduos agroindustriais e aplicação na produção de biodiesel. [Thesis]. Universidade Estadual Paulista; 2017. Available from: http://hdl.handle.net/11449/148890
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
NSYSU
27.
Kao, Man-hua.
The Study of Customer Management in the Age of Dataï¼A Case of Company A.
Degree: Master, Business Management, 2017, NSYSU
URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0604117-175648
► For most industries, customers are important assets for the enterprises. The emergence of new customers and the loss of existing customers are inevitable. Hence how…
(more)
▼ For most industries, customers are important assets for the enterprises. The emergence of new customers and the loss of existing customers are inevitable. Hence how to build up the long-term relationship between company and customers by giving them appropriate care, or to sacrifice a certain level of those low profitable customers in order to increase maximum profit has always been the aim of customer relationship management (Customer Relationship Management, CRM).ã
ããWith the evolution of the times and technology, data analysis has become an important part of customer relationship management. Once transactions were generated, the enterprises will be able to use the records to calculate the customer lifetime value (Customer Lifetime Value, CLV). In other words, the value can be utilize by the enterprise to predict customersâ future contribution level via customersâ previous consumption behaviors. Enterprises could develop different CRM based on different CLV.
ããIn recent years, customer relationship management has been widely used in the financial industry, insurance industry, general retail industry, etc. However, this study will focus on the development of CRM in hairdressing industry. In addition to the feature of physical channels and a fixed frequency of consumption of customers, the loyalty of customers will be lessened by hair designers, which could not be seen in other industries. Therefore, how to increase customersâ loyalty to companies is an important key of the development CRM.
ããThrough a case study and background research of company A, this study further analyze the customer transaction records between 2009 to 2016 by applying
NES model to segment customers. Using regression analysis to predict CLV of each segmentation, and giving different strategic advices based on the regression analysis and the customer management matrix proposed by Kumar and Rajan to develop and retain customers for company A. This study will provide a set of customer relationship management practices that can be used effectively in Taiwan's hairdressing industry. It is advisable for Taiwanese managers in hairdressing industry, when they are making marketing strategies by data.
Advisors/Committee Members: Chi-Cheng Wu (committee member), Hsuan-Yi Chou (chair), Wei-Ning Wu (chair).
Subjects/Keywords: Data; CLV; Segmentation; CRM; NES model
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APA ·
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Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kao, M. (2017). The Study of Customer Management in the Age of Dataï¼A Case of Company A. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0604117-175648
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Kao, Man-hua. “The Study of Customer Management in the Age of Dataï¼A Case of Company A.” 2017. Thesis, NSYSU. Accessed January 19, 2021.
http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0604117-175648.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Kao, Man-hua. “The Study of Customer Management in the Age of Dataï¼A Case of Company A.” 2017. Web. 19 Jan 2021.
Vancouver:
Kao M. The Study of Customer Management in the Age of Dataï¼A Case of Company A. [Internet] [Thesis]. NSYSU; 2017. [cited 2021 Jan 19].
Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0604117-175648.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Kao M. The Study of Customer Management in the Age of Dataï¼A Case of Company A. [Thesis]. NSYSU; 2017. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0604117-175648
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Iceland
28.
Hrafnhildur Þórólfsdóttir.
Náttúra og saga í Nesi við Seltjörn - verkefnasafn og greinargerð
.
Degree: 2011, University of Iceland
URL: http://hdl.handle.net/1946/9577
► Greinargerð þessi og verkefnasafn er lokaverkefni til B.Ed.- prófs frá menntavísindasviði Háskóla Íslands. Í verkefnasafninu eru þrettán verkefni sem tengjast á einn eða annan hátt…
(more)
▼ Greinargerð þessi og verkefnasafn er lokaverkefni til B.Ed.- prófs frá menntavísindasviði Háskóla Íslands.
Í verkefnasafninu eru þrettán verkefni sem tengjast á einn eða annan hátt Urtagarðinum í Nesi á Seltjarnarnesi og/eða Lækningaminjasafni Íslands sem starfrækt er í Nesstofu á sama stað. Sagt er frá tilurð og skipulagi Urtagarðsins sem opnaður var á safnasvæðinu í Nesi sumarið 2010.
Í greinagerðinni er fjallað um kennslufræðilegan bakgrunn verkefnanna, þar á meðal grenndarnám og safnanám. Sú kennslufræði sem verkefnasafnið byggir að mestu leyti á eru kenningar Vygotskys og Deweys sem báðir fjölluðu um nám og þroska barna. Áhersla er lögð á mikilvægi reynslunnar og upplifunar í námi en einnig er fjallað um lykilhugtak í kenningum Vygotskys; svæði mögulegrar þróunar (e. zone of proximal development).
Að lokum er verkefnasafnið kynnt og gert grein fyrir markmiðum verkefnanna.
Subjects/Keywords: Grunnskólakennarafræði;
Kennsluverkefni;
Nes við Seltjörn;
Safnafræði
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Þórólfsdóttir, H. (2011). Náttúra og saga í Nesi við Seltjörn - verkefnasafn og greinargerð
. (Thesis). University of Iceland. Retrieved from http://hdl.handle.net/1946/9577
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Þórólfsdóttir, Hrafnhildur. “Náttúra og saga í Nesi við Seltjörn - verkefnasafn og greinargerð
.” 2011. Thesis, University of Iceland. Accessed January 19, 2021.
http://hdl.handle.net/1946/9577.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Þórólfsdóttir, Hrafnhildur. “Náttúra og saga í Nesi við Seltjörn - verkefnasafn og greinargerð
.” 2011. Web. 19 Jan 2021.
Vancouver:
Þórólfsdóttir H. Náttúra og saga í Nesi við Seltjörn - verkefnasafn og greinargerð
. [Internet] [Thesis]. University of Iceland; 2011. [cited 2021 Jan 19].
Available from: http://hdl.handle.net/1946/9577.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Þórólfsdóttir H. Náttúra og saga í Nesi við Seltjörn - verkefnasafn og greinargerð
. [Thesis]. University of Iceland; 2011. Available from: http://hdl.handle.net/1946/9577
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Johannes Gutenberg Universität Mainz
29.
Fetz, Verena.
Identifizierung chemischer Transportinhibitoren zur Modulation (patho)biologischer Genprodukte.
Degree: 2012, Johannes Gutenberg Universität Mainz
URL: http://ubm.opus.hbz-nrw.de/volltexte/2012/3199/
► Die intrazelluläre Lokalisation von Proteinen und Makromolekülen unterliegt in Eukaryoten einer strengen Regulation. Insbesondere erlaubt die Kompartimentierung eukaryotischer Zellen in Zellkern und Zytoplasma den simultanen…
(more)
▼ Die intrazelluläre Lokalisation von Proteinen und Makromolekülen unterliegt in Eukaryoten einer strengen Regulation. Insbesondere erlaubt die Kompartimentierung eukaryotischer Zellen in Zellkern und Zytoplasma den simultanen Ablauf räumlich getrennter biochemischer Reaktionen, und damit die unabhängige Regulation zellulärer Programme. Da trotz intensiver Forschungsbemühungen bis dato die molekularen Details sowie die (patho)biologische Bedeutung von Kern-Zytoplasma-Transportprozessen noch immer nicht vollkommen verstanden sind, wurde im Rahmen der vorliegenden Arbeit ein Fokus auf die Identifizierung von chemischen Transportinhibitoren gelegt. Das zu diesem Zweck entwickelte Translokations-Biosensor-System basiert auf der Kombination von autofluoreszierenden Proteinen, sowie spezifisch ausgewählten Kernexport- und Kernimportsignalen. Nach Etablierung geeigneter Zellmodelle, die effizient und stabil die Translokations-Biosensoren exprimieren, wurde die 17 000 Substanzen umfassende Bibliothek der ChemBioNet-Initiative nach Kernexportinhibitoren mittels einer Fluoreszenzmikroskopie-basierten Hochdurchsatzanalyse-Plattform durchmustert. Zunächst wurden Translokations-Algorithmen, welche eine zuverlässige automatisierte Erkennung von Zellkern und Zytoplasma erlauben, optimiert. Im Folgenden konnten acht neue niedermolekulare Kernexport-Inhibitoren identifiziert werden, die sich in der Stärke, der Geschwindigkeit, sowie in der Beständigkeit der vermittelten Inhibition unterscheiden. Die Aktivität der Inhibitoren konnte auf den isolierten nukleären Exportsignalen (NES) von HIV-1 Rev und Survivin als auch auf den entsprechenden Volllängeproteinen mittels Mikroinjektionsexperimenten sowie durch umfassende in vitro und biochemische Methoden bestätigt werden. Zur Untersuchung der funktionellen Einheiten der Inhibitoren wurden homologe Substanzen auf Ihre Aktivität hin getestet. Dabei konnten für die Aktivität wichtige chemische Gruppen definiert werden. Alle Substanzen stellen neue Inhibitoren des Crm1-abhängigen Exports dar und zeigen keine nachweisbare NES-Selektivität. Interessanterweise konnte jedoch eine zytotoxische und Apoptose-induzierende Wirkung auf verschiedene Krebszellarten festgestellt werden. Da diese Wirkung unabhängig vom p53-Status der Tumorzellen ist und die Inhibitoren C3 und C5 die Vitalität nicht-maligner humaner Zellen signifikant weniger beeinträchtigen, wurden diese Substanzen zum internationalen Patent angemeldet. Da der nukleäre Export besonders für Tumorzellen einen wichtigen Überlebenssignalweg darstellt, könnte dessen reversible Hemmung ausgenutzt werden, um besonders in Kombination mit gängigen Krebstherapien eine therapeutisch relevante Tumorinhibition zu erzeugen. Eine weitere Anwendungsmöglichkeit der neuen Exportinhibitoren ist auf dem Gebiet der Infektionskrankheiten zu sehen, da auch die Aktivität des essentiellen HIV-1 Rev-Proteins inhibiert wird. Zusätzlich konnte in der Arbeit gezeigt werden, dass der zelluläre Kofaktor des Crm1-abhängigen Exports des HIV-1 Rev-Proteins, die RNA-Helikase…
Subjects/Keywords: Kern-Zytoplasma-Transport; Crm1; NES; nucleocytoplasmic transport; Crm1; NES; Natural sciences and mathematics
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APA (6th Edition):
Fetz, V. (2012). Identifizierung chemischer Transportinhibitoren zur Modulation (patho)biologischer Genprodukte. (Doctoral Dissertation). Johannes Gutenberg Universität Mainz. Retrieved from http://ubm.opus.hbz-nrw.de/volltexte/2012/3199/
Chicago Manual of Style (16th Edition):
Fetz, Verena. “Identifizierung chemischer Transportinhibitoren zur Modulation (patho)biologischer Genprodukte.” 2012. Doctoral Dissertation, Johannes Gutenberg Universität Mainz. Accessed January 19, 2021.
http://ubm.opus.hbz-nrw.de/volltexte/2012/3199/.
MLA Handbook (7th Edition):
Fetz, Verena. “Identifizierung chemischer Transportinhibitoren zur Modulation (patho)biologischer Genprodukte.” 2012. Web. 19 Jan 2021.
Vancouver:
Fetz V. Identifizierung chemischer Transportinhibitoren zur Modulation (patho)biologischer Genprodukte. [Internet] [Doctoral dissertation]. Johannes Gutenberg Universität Mainz; 2012. [cited 2021 Jan 19].
Available from: http://ubm.opus.hbz-nrw.de/volltexte/2012/3199/.
Council of Science Editors:
Fetz V. Identifizierung chemischer Transportinhibitoren zur Modulation (patho)biologischer Genprodukte. [Doctoral Dissertation]. Johannes Gutenberg Universität Mainz; 2012. Available from: http://ubm.opus.hbz-nrw.de/volltexte/2012/3199/
Siauliai University
30.
Milašiūtė,
Aurelija.
Dailės terapijos poveikis bendravimo įgūdžių
plėtojimui, dirbant su priešmokyklinio amžiaus vaikais, turinčiais
elgesio ir emocijų sunkumų.
Degree: Master, Educology, 2014, Siauliai University
URL: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2014~D_20140717_154141-95495
;
► Darbe atlikta teorinė elgesio ir emocijų sunkumų turinčių vaikų samprata, sutrikimų atsiradimo priežastys, dailės terapijos galimybės bendravimo įgūdžių plėtojimui, analizė. Kvazieksperimento metodu atliktas tyrimas, kurio…
(more)
▼ Darbe atlikta teorinė elgesio ir emocijų
sunkumų turinčių vaikų samprata, sutrikimų atsiradimo priežastys,
dailės terapijos galimybės bendravimo įgūdžių plėtojimui, analizė.
Kvazieksperimento metodu atliktas tyrimas, kurio tikslas - ištirti
dailės terapijos poveikį bendravimo įgūdžių plėtojimui, ugdant
priešmokyklinio amžiaus vaikus, turinčius elgesio ir emocijų
sunkumų. Atlikta matematinė aprašomoji duomenų analizė, pateikta
naudojant atvejo analizės metodą. Tyrime dalyvavo patogiuoju būdu
atrinkti 9 priešmokyklinio amžiaus vaikai, turintys elgesio ir
emocijų sunkumų, kurie sudarė tikslinę grupę. Empirinėje dalyje
analizuoti stebėjimo protokoluose užfiksuoti duomenys apie
bendravimo įgūdžių raišką, dinamiką dailės terapijos sesijos metu,
stebėtas poveikis. Diagnostinių piešinių testais analizuota
ugdytinių bendravimo įgūdžių požymių kaita. Ieškota bendravimo
įgūdžių požymių piešiniuose bei bendravimo įgūdžių duomenų,
fiksuotų stebėjimo protokoluose, sąsajos. Atlikus tyrimo duomenų
analizę, suformuluotos pagrindinės išvados: • Stebėjimo protokolų
duomenys parodė tendenciją dailės terapijos sesijų metu pasireikšti
pozityviai bendravimo raiškai. • pirminio ir baigiamojo
diagnostinių H-T-P piešinių rezultatai atskleidė bendravimo požymių
piešiniuose kitimą teigiama linkme. Žemos savivertės, agresyvumo,
depresyvumo požymių, įtakojančių žemą bendravimo poreikį ar
neigiamą bendravimo raišką, sumažėjo, o bendravimo poreikio požymių
padaugėjo.
The paper deals with theoretical analysis of
children with emotional and behavioral difficulties and
opportunities of art therapy in developing communication skills.
The purpose of investigation was to find out whether art therapy
has a positive effect on the development of communication skills of
preschool children with emotional and behavioral difficulties.
Quasi-experimental method was used to investigate art therapy
effect. The mathematical descriptive analysis of the data was
presented using the case study method. The study included 9
preschool children with behavioral and emotional difficulties,
target group was selected using convenient way. In empirical part
were analyzed data, about resolution skills and dynamics of the art
therapy in sessions. By the help of diagnostic drawing tests
attributes of communication skills were analyzed and captured in
monitoring protocols. After the data analysis, the most important
empirical conclusions that were drawn are: 1. Performed experiment
revealed positive effect of art therapy on the development of
social and communication skills. 2. Monitoring protocols showed a
tendency to unfold the expression of positive communication 3.
H-T-P drawing test results revealed positive direction. Low
self-esteem, aggression, depressive symptoms, affecting the low
need for communication or expression of negative communication
decreased after experiment.
Advisors/Committee Members: Bagdomas, Albinas (Master’s degree committee chair), Kaffemanienė, Irena (Master’s degree committee member), Gudonis, Vytautas (Master’s degree committee member), Ivoškuvienė, Regina (Master’s degree committee member), Miltenienė, Lina (Master’s degree committee member), Jundulienė, Asta (Master’s degree session secretary), Vaitkevičienė, Asta (Master’s thesis supervisor), Bražienė, Nijolė (Master’s thesis reviewer).
Subjects/Keywords: Dailės
terapija; Grupinė dailės
terapija; Elgesio ir emocijų
sunkumai; Bendravimo
įgūdžiai; H-T-P; Art therapy; Group art
therapy; Behavioral and emotional
difficulties; Communication
skills; H-T-P
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Milašiūtė,
Aurelija. (2014). Dailės terapijos poveikis bendravimo įgūdžių
plėtojimui, dirbant su priešmokyklinio amžiaus vaikais, turinčiais
elgesio ir emocijų sunkumų. (Masters Thesis). Siauliai University. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2014~D_20140717_154141-95495 ;
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Chicago Manual of Style (16th Edition):
Milašiūtė,
Aurelija. “Dailės terapijos poveikis bendravimo įgūdžių
plėtojimui, dirbant su priešmokyklinio amžiaus vaikais, turinčiais
elgesio ir emocijų sunkumų.” 2014. Masters Thesis, Siauliai University. Accessed January 19, 2021.
http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2014~D_20140717_154141-95495 ;.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
MLA Handbook (7th Edition):
Milašiūtė,
Aurelija. “Dailės terapijos poveikis bendravimo įgūdžių
plėtojimui, dirbant su priešmokyklinio amžiaus vaikais, turinčiais
elgesio ir emocijų sunkumų.” 2014. Web. 19 Jan 2021.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Vancouver:
Milašiūtė,
Aurelija. Dailės terapijos poveikis bendravimo įgūdžių
plėtojimui, dirbant su priešmokyklinio amžiaus vaikais, turinčiais
elgesio ir emocijų sunkumų. [Internet] [Masters thesis]. Siauliai University; 2014. [cited 2021 Jan 19].
Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2014~D_20140717_154141-95495 ;.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Council of Science Editors:
Milašiūtė,
Aurelija. Dailės terapijos poveikis bendravimo įgūdžių
plėtojimui, dirbant su priešmokyklinio amžiaus vaikais, turinčiais
elgesio ir emocijų sunkumų. [Masters Thesis]. Siauliai University; 2014. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2014~D_20140717_154141-95495 ;
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
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Open Access Theses and Dissertations
