You searched for subject:(Iron deficiency anemia).
Showing records 1 – 30 of
135 total matches.
◁ [1] [2] [3] [4] [5] ▶
University of Aberdeen
1.
Mossa-Al Hashimi, Lina.
Effect of iron deficiency on membrane structure and function.
Degree: PhD, 2013, University of Aberdeen
URL: https://eu03.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12152527110005941 
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.577623
► Iron deficiency is one of the most common nutritional disorders worldwide. It is especially serious during pregnancy with serious health consequences for both the mother…
(more)
▼ Iron deficiency is one of the most common nutritional disorders worldwide. It is especially serious during pregnancy with serious health consequences for both the mother and her developing fetus. In humans these include fetal growth retardation, impaired cognitive development and premature birth. In rats, the pups born to iron deficient mothers are smaller, with changes in liver and heart size. As adults, the offspring develop hypertension and obesity. Why these changes occur is not clear. One possible hypothesis is that iron deficiency changes the cell membrane. I aimed to investigate this hypothesis, using an in-house iron deficient maternal rat model, designed by our group, additionally I have designed an iron deficient human liver hepatoma cell line model (HepG2). The effect of iron deficiency on maternal and neonatal erythrocytes membranes was tested. Iron deficiency significantly increased the mothers’ erythrocytes sensitivity to low osmotic pressure. In contrast, the neonates’ erythrocytes sensitivity was not affected by iron deficiency. The effect of iron deficiency on membrane protein profile was also studied in maternal and neonatal liver total membrane proteins, using proteomics analysis. Mitochondrial proteins were the most affected, especially in neonates. Whole cell patch clamp recording was used to study the effect of iron deficiency on the membranes’ electrophysiological properties. HepG2 cells had linear current-voltage relationships between -130 and +60 mV. Furthermore iron deficiency reduced the membranes’ input resistance reflected by an increase in holding current and in slope conductance. These changes were not reversed by K+ channel blockers (Ba2+ and quinine) suggesting no change in K+ channel protein expression. Interestingly and unexpectedly it increased the change in conductance, Sr2+ had a similar effect. Therefore iron deficient membranes had increased permeabilit
Subjects/Keywords: 616.1; Iron deficiency anemia
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mossa-Al Hashimi, L. (2013). Effect of iron deficiency on membrane structure and function. (Doctoral Dissertation). University of Aberdeen. Retrieved from https://eu03.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12152527110005941 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.577623
Chicago Manual of Style (16th Edition):
Mossa-Al Hashimi, Lina. “Effect of iron deficiency on membrane structure and function.” 2013. Doctoral Dissertation, University of Aberdeen. Accessed January 23, 2021.
https://eu03.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12152527110005941 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.577623.
MLA Handbook (7th Edition):
Mossa-Al Hashimi, Lina. “Effect of iron deficiency on membrane structure and function.” 2013. Web. 23 Jan 2021.
Vancouver:
Mossa-Al Hashimi L. Effect of iron deficiency on membrane structure and function. [Internet] [Doctoral dissertation]. University of Aberdeen; 2013. [cited 2021 Jan 23].
Available from: https://eu03.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12152527110005941 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.577623.
Council of Science Editors:
Mossa-Al Hashimi L. Effect of iron deficiency on membrane structure and function. [Doctoral Dissertation]. University of Aberdeen; 2013. Available from: https://eu03.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12152527110005941 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.577623
University of Guelph
2.
Charles, Christopher Vaughn.
Happy Fish: A Novel Iron Supplementation Technique to
Prevent Iron Deficiency Anemia in Women in Rural Cambodia.
Degree: PhD, Biomedical Sciences, 2012, University of Guelph
URL: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/3638
► Maternal and child undernutrition are a significant problem in the developing world, with serious consequences for human health and socio-economic development. In Cambodia, 55% of…
(more)
▼ Maternal and child undernutrition are a significant
problem in the developing world, with serious consequences for
human health and socio-economic development. In Cambodia, 55% of
children, 43% of women of reproductive age, and 50% of pregnant
women are anemic. Current prevention and control practices rely on
supplementation with
iron pills or large-scale food fortification,
neither of which are affordable or feasible in rural Cambodia. In
the study areas, 97% of women did not meet their daily
iron
requirements. The current research focuses on the design and
evaluation of an innovative
iron supplementation technique. A
culturally acceptable, inexpensive and lightweight
iron ingot was
designed to resemble a fish species considered lucky in Khmer
culture. The ingot, referred to as ‘try sabay’ or ‘happy fish’, was
designed to supply
iron at a slow, steady rate.
Iron leaching was
observed in water and soup samples prepared with the
iron fish when
used concurrently with an acidifier. More than 75% of daily
iron
requirements can be met with regular use. Its use in the common pot
of soup or boiled water provides supplementation to the entire
family. The effectiveness of the
iron fish was investigated in a
randomized community trial involving 310 women in rural Cambodia.
Blood samples were taken at baseline and every three months
thereafter, over a 12-month trial period. Significant increases in
hemoglobin concentrations were observed in women allocated an
iron
fish when compared to controls throughout the study, with an
endline difference of 11.6 g/L. Significant improvements in serum
ferritin concentration were observed at 9 months (6.9 ng/mL) and
endline (30.8 ng/mL) in women who used an
iron fish regularly when
compared to the control group. Overall, use of the
iron fish led to
a two-fold reduction in the prevalence of
anemia. The supplement
was used daily by 94% of the households at the end of the trial.
The study highlights the acceptability and effectiveness of a
fish-shaped
iron ingot as a means of improving dietary
iron
content. It offers a promising, simple solution to
iron deficiency
anemia if the project can be scaled-up for use throughout the
country.
Advisors/Committee Members: Summerlee, Alastair, Dewey, Cate.
Subjects/Keywords: Anemia; Cambodia; Iron deficiency; Iron fish; Supplementation
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Charles, C. V. (2012). Happy Fish: A Novel Iron Supplementation Technique to
Prevent Iron Deficiency Anemia in Women in Rural Cambodia. (Doctoral Dissertation). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/3638
Chicago Manual of Style (16th Edition):
Charles, Christopher Vaughn. “Happy Fish: A Novel Iron Supplementation Technique to
Prevent Iron Deficiency Anemia in Women in Rural Cambodia.” 2012. Doctoral Dissertation, University of Guelph. Accessed January 23, 2021.
https://atrium.lib.uoguelph.ca/xmlui/handle/10214/3638.
MLA Handbook (7th Edition):
Charles, Christopher Vaughn. “Happy Fish: A Novel Iron Supplementation Technique to
Prevent Iron Deficiency Anemia in Women in Rural Cambodia.” 2012. Web. 23 Jan 2021.
Vancouver:
Charles CV. Happy Fish: A Novel Iron Supplementation Technique to
Prevent Iron Deficiency Anemia in Women in Rural Cambodia. [Internet] [Doctoral dissertation]. University of Guelph; 2012. [cited 2021 Jan 23].
Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/3638.
Council of Science Editors:
Charles CV. Happy Fish: A Novel Iron Supplementation Technique to
Prevent Iron Deficiency Anemia in Women in Rural Cambodia. [Doctoral Dissertation]. University of Guelph; 2012. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/3638
3.
Cruz, Rodrigo Danelon da.
Avaliação da deficiência de ferro durante o processo gestacional e sua relação com o consumo alimentar e a suplementação com ferro.
Degree: Mestrado, Análises Clínicas, 2010, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/9/9136/tde-05042010-163741/
;
► A deficiência de ferro e anemia ferropriva são problemas de ordem mundial. Para as mulheres no período gestacional, a preocupação com o estado do ferro…
(more)
▼ A deficiência de ferro e anemia ferropriva são problemas de ordem mundial. Para as mulheres no período gestacional, a preocupação com o estado do ferro no organismo deve ser ainda maior, pois a deficiência desse elemento pode causar prejuízo na formação dos bebês. O objetivo do projeto é avaliar a evolução da freqüência de deficiência de ferro e anemia ferropriva e os parâmetros de ferro no organismo de mulheres grávidas durante toda a gestação e relacionar com dados da dieta e suplementação de ferro. Também avaliamos os dados sócio-demográficos e nutricionais maternos, além dos parâmetros de ferro, com o peso dos seus recém nascidos. Participaram do estudo 183 gestantes, 103 terminaram o protocolo e das quais foram colhidas amostras de sangue nas idades gestacionais de 16, 28 e 36 semanas. Para avaliação nutricional foram aplicados três inquéritos recordatórios de 24 horas no dia da coleta. Foram realizadas as determinações de ferro sérico, saturação de transferrina, ferritina sérica, capacidade total de ligação ao ferro (CTLF) e concentração sérica do receptor de transferrina (sTfR), além da dosagem da concentração de hemoglobina. As gestantes foram classificadas em seis grupos conforme a suplementação com ferro em cada idade gestacional: as mulheres que não utilizaram essa suplementação foram incluídas no grupo 1 (N=21); enquanto as participantes que fizeram o uso de suplementação em todas as idades gestacionais, até 16 semanas de gravidez e com 28 e 36 semanas de gestação foram incluídas nos grupos 2 (N= 17), 3 (N=12) e 4 (N=24), respectivamente. Os outros 2 grupos foram constituídos por mulheres que utilizaram a suplementação somente com 28 semanas de gestação (Grupo 5, N= 19) e com 36 semanas de gestação (grupo 6 , N= 10). Não houve correlação entre os consumo de ferro da dieta e os parâmetros que avaliam o estado do ferro no sangue. Houve aumento da freqüência de deficiência de ferro em todos os grupos estudados, mas não ocorreu aumento da freqüência de anemia e nem anemia ferropriva.
Iron deficiency and iron deficiency anemia are worldwilde problems. For women during pregnancy, concern about the iron status should be even higher, because the iron deficiency may impair the formation of newborn. The objectives of this work was evaluate the frequency of iron deficiency and iron deficiency anemia and iron status markers of pregnant women during pregnancy and correlate with diet intake and iron supplementation. We also assess the socio-demographic, maternal nutrition and iron status with birth weight of their newborns. The study included 183 women, 103 completed the protocol. Blood samples was collected at gestational ages of 16, 28 and 36 weeks. Nutrient intake was assessed by 24 hour dietary recall applied at the same time of blood samples. We analyzed serum iron, transferrin saturation, serum ferritin, total iron binding capacity (TIBC), serum transferrin receptor (sTfR), and hemoglobin. Patients were classified into six groups according to iron supplementation: women who did not use this supplement were…
Advisors/Committee Members: Guerra-Shinohara, Elvira Maria.
Subjects/Keywords: Anemia; Anemia; Anemia ferropriva; Deficiência de ferro; Gravidez; Iron deficiency; Iron deficiency anemia; Iron supplementation; Pregnancy; Suplementação de ferro
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Cruz, R. D. d. (2010). Avaliação da deficiência de ferro durante o processo gestacional e sua relação com o consumo alimentar e a suplementação com ferro. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/9/9136/tde-05042010-163741/ ;
Chicago Manual of Style (16th Edition):
Cruz, Rodrigo Danelon da. “Avaliação da deficiência de ferro durante o processo gestacional e sua relação com o consumo alimentar e a suplementação com ferro.” 2010. Masters Thesis, University of São Paulo. Accessed January 23, 2021.
http://www.teses.usp.br/teses/disponiveis/9/9136/tde-05042010-163741/ ;.
MLA Handbook (7th Edition):
Cruz, Rodrigo Danelon da. “Avaliação da deficiência de ferro durante o processo gestacional e sua relação com o consumo alimentar e a suplementação com ferro.” 2010. Web. 23 Jan 2021.
Vancouver:
Cruz RDd. Avaliação da deficiência de ferro durante o processo gestacional e sua relação com o consumo alimentar e a suplementação com ferro. [Internet] [Masters thesis]. University of São Paulo; 2010. [cited 2021 Jan 23].
Available from: http://www.teses.usp.br/teses/disponiveis/9/9136/tde-05042010-163741/ ;.
Council of Science Editors:
Cruz RDd. Avaliação da deficiência de ferro durante o processo gestacional e sua relação com o consumo alimentar e a suplementação com ferro. [Masters Thesis]. University of São Paulo; 2010. Available from: http://www.teses.usp.br/teses/disponiveis/9/9136/tde-05042010-163741/ ;
Massey University
4.
Moor, Charlotte Felicity.
Iron status of preterm infants after hospital discharge.
Degree: Masters, Science in Nutrition and Dietetics, 2013, Massey University
URL: http://hdl.handle.net/10179/5205
► Background: Preterm infants are at an increased risk of developing iron deficiency (defined in paeditaric populations as a ferritin value <12 μg/L or a serum…
(more)
▼ Background: Preterm infants are at an increased risk of developing iron deficiency
(defined in paeditaric populations as a ferritin value <12 μg/L or a serum transferrin
receptor concentration >2.4 mg/L) after discharge due to their shortened gestational
length, increased requirements for rapid growth, and excessive blood losses through
phlebotomy. Optimising preterm infant iron status after discharge is important as poor
iron status has been associated with negative health and neurodevelopmental
outcomes later in life. Only preterm infants born before 32 weeks gestation or with a
birth weight less than 1800 g currently receive routine iron supplementation after
discharge from Auckland City Hospital; however there is paucity of evidence to
determine whether this is best practice.
Objective: To investigate the iron status of preterm infants in Auckland, New Zealand
at four months after discharge from hospital.
Methods: Sixty one preterm infants were recruited through Auckland City Hospital. At
four months after discharge infant haemoglobin, serum ferritin and soluble transferrin
receptor (sTfR) concentrations were measured to assess iron status. Weight, length
and head circumference were also measured. Information about iron supplementation
and mode of feeding was collected using an online questionnaire. Statistical analysis
using independent t-tests, Mann-Whitney tests and bivariate correlations were
performed.
Results: 16.4% of preterm infants had iron deficiency anaemia (defined in paediatric
populations as a haemoglobin less than 110 g/L in conjunction with low iron stores) at
four months after discharge, with an additional 6.6% of preterm infants classified as
having iron deficiency. No infant had iron overload. Iron supplementation was
associated with significantly higher haemoglobin (P<0.001) and serum ferritin
(P<0.001) concentrations along with lower sTfR concentrations (P=0.005) at four
months after discharge. Iron supplementation was also protective against suboptimal
iron status at four months after discharge (P=0.018). Mode of feeding, introduction of
solids, intrauterine growth restriction, and maternal iron status had no effect on infant
iron status at four months after discharge. There was also no relationship between
growth and iron supplementation or iron status at four months after discharge.
Conclusion: Preterm infants who did not receive iron supplements after discharge had
an increased risk of developing iron deficiency and iron deficiency anaemia at four
months after discharge. Routine iron supplementation for all preterm infants
combined with screening for iron deficiency anaemia after discharge appears to be a
safe and effective way to reduce the risk of iron deficiency and iron deficiency anaemia
at four months after discharge.
Subjects/Keywords: Preterm infants;
Premature infants;
Iron deficiency;
Iron deficiency anemia in infants
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Moor, C. F. (2013). Iron status of preterm infants after hospital discharge. (Masters Thesis). Massey University. Retrieved from http://hdl.handle.net/10179/5205
Chicago Manual of Style (16th Edition):
Moor, Charlotte Felicity. “Iron status of preterm infants after hospital discharge.” 2013. Masters Thesis, Massey University. Accessed January 23, 2021.
http://hdl.handle.net/10179/5205.
MLA Handbook (7th Edition):
Moor, Charlotte Felicity. “Iron status of preterm infants after hospital discharge.” 2013. Web. 23 Jan 2021.
Vancouver:
Moor CF. Iron status of preterm infants after hospital discharge. [Internet] [Masters thesis]. Massey University; 2013. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/10179/5205.
Council of Science Editors:
Moor CF. Iron status of preterm infants after hospital discharge. [Masters Thesis]. Massey University; 2013. Available from: http://hdl.handle.net/10179/5205
Oregon State University
5.
Chao, Lucia Sy-Jing Lo.
Influence of fish on the bioavailability of plant iron in the anemic rat.
Degree: MS, Food Science and Technology, 1979, Oregon State University
URL: http://hdl.handle.net/1957/26147
Subjects/Keywords: Iron deficiency anemia
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Chao, L. S. L. (1979). Influence of fish on the bioavailability of plant iron in the anemic rat. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/26147
Chicago Manual of Style (16th Edition):
Chao, Lucia Sy-Jing Lo. “Influence of fish on the bioavailability of plant iron in the anemic rat.” 1979. Masters Thesis, Oregon State University. Accessed January 23, 2021.
http://hdl.handle.net/1957/26147.
MLA Handbook (7th Edition):
Chao, Lucia Sy-Jing Lo. “Influence of fish on the bioavailability of plant iron in the anemic rat.” 1979. Web. 23 Jan 2021.
Vancouver:
Chao LSL. Influence of fish on the bioavailability of plant iron in the anemic rat. [Internet] [Masters thesis]. Oregon State University; 1979. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/1957/26147.
Council of Science Editors:
Chao LSL. Influence of fish on the bioavailability of plant iron in the anemic rat. [Masters Thesis]. Oregon State University; 1979. Available from: http://hdl.handle.net/1957/26147
Vanderbilt University
6.
Beckett, Amber Celeste.
Interplay between Helicobacter pylori, diet and disease.
Degree: PhD, Microbiology and Immunology, 2018, Vanderbilt University
URL: http://hdl.handle.net/1803/10532
► Epidemiologic studies have provided conflicting data regarding an association between Helicobacter pylori infection and iron deficiency anemia (IDA) in humans. In this thesis, I describe…
(more)
▼ Epidemiologic studies have provided conflicting data regarding an association between Helicobacter pylori infection and
iron deficiency anemia (IDA) in humans. In this thesis, I describe the use of a Mongolian gerbil model to investigate potential roles of H. pylori infection and diet in IDA. The experimental results indicate that H. pylori infection can cause IDA and that the composition of the diet influences the incidence and severity of H. pylori-induced IDA. Additionally, a high salt diet increased the incidence of gastric ulceration in infected gerbils. Finally, I examined H. pylori genetic adaptation in the Mongolian gerbil stomach. This environment is of particular interest because H. pylori-infected gerbils develop severe gastric inflammation and often develop gastric adenocarcinoma or gastric ulceration. I analyzed the whole genome sequences of H. pylori strains cultured from experimentally infected gerbils in comparison to the genome sequence of the input strain, and identified numerous polymorphisms that were positively selected in vivo.
Advisors/Committee Members: Jim Cassat (committee member), Thomas Aune (committee member), Mary Kay Washington (committee member), Holly Algood (committee member), David Aronoff (Committee Chair).
Subjects/Keywords: H. pylori; anemia; iron deficiency; gastric cancer
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Beckett, A. C. (2018). Interplay between Helicobacter pylori, diet and disease. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/10532
Chicago Manual of Style (16th Edition):
Beckett, Amber Celeste. “Interplay between Helicobacter pylori, diet and disease.” 2018. Doctoral Dissertation, Vanderbilt University. Accessed January 23, 2021.
http://hdl.handle.net/1803/10532.
MLA Handbook (7th Edition):
Beckett, Amber Celeste. “Interplay between Helicobacter pylori, diet and disease.” 2018. Web. 23 Jan 2021.
Vancouver:
Beckett AC. Interplay between Helicobacter pylori, diet and disease. [Internet] [Doctoral dissertation]. Vanderbilt University; 2018. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/1803/10532.
Council of Science Editors:
Beckett AC. Interplay between Helicobacter pylori, diet and disease. [Doctoral Dissertation]. Vanderbilt University; 2018. Available from: http://hdl.handle.net/1803/10532
7.
Chikwanda, Ephraim.
Evaluation of hepcidin as a potential biomaker for the differential diagnosis of iron deficiency anaemia and anaemia of chronic disease at Ndola central hospital,Zambia.
Degree: 2017, University of Zimbabwe
URL: http://dspace.unza.zm/handle/123456789/6331
► Anaemia affects approximately 1.62 billion people globally corresponding to 24.8% of the world’s population. Iron deficiency anaemia (IDA) and anaemia of chronic disease (ACD) are…
(more)
▼ Anaemia affects approximately 1.62 billion people globally corresponding to 24.8% of the world’s population. Iron deficiency anaemia (IDA) and anaemia of chronic disease (ACD) are the most common forms of anaemia. A hormone produced by the liver, hepcidin, is the primary regulator of iron homeostasis and its production increases in ACD and decreases in IDA. Usually, ACD and IDA coexist and sometimes look identical on peripheral blood smears.
The current study aims to evaluate the diagnostic value of hepcidin to predict ACD from IDA as well as the diagnostic value of hepcidin to predict ACD from a combination of IDA and ACD.
Specimens presenting with haematological indices suggestive of IDA and/or ACD following World Health Organisation (WHO) standard case definitions were identified among samples coming to the Haematology laboratory for routine investigations. Serum hepcidin, serum ferritin, serum iron and total iron binding capacity (TIBC) were assessed. Demographic data was obtained from specimen requisition forms.
Of the 66 participants, 62.1% (n = 41) were females and IDA was more common among females (36.4%) than males (6.1%) while ACD was more common in males (19.7%) than females (12.1%). Anaemia of chronic disease participants had significantly higher hepcidin levels than IDA and IDA/ACD (p<0.001). There was a significant positive correlation between serum hepcidin and serum ferritin levels (p < 0.001).
We found that IDA participants had significantly lower hepcidin levels than ACD and IDA/ACD combined. Therefore, serum hepcidin could be considered in diagnosing and distinguishing ACD from IDA or IDA/ACD as it also had high diagnostic sensitivity and specificity compared to other markers.
Key words: Hepcidin; Iron Deficiency Anaemia; Anaemia of chronic Disease.
Subjects/Keywords: Anaemia – Chronic Disease; Iron deficiency anemia – Zambia
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Chikwanda, E. (2017). Evaluation of hepcidin as a potential biomaker for the differential diagnosis of iron deficiency anaemia and anaemia of chronic disease at Ndola central hospital,Zambia. (Thesis). University of Zimbabwe. Retrieved from http://dspace.unza.zm/handle/123456789/6331
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Chikwanda, Ephraim. “Evaluation of hepcidin as a potential biomaker for the differential diagnosis of iron deficiency anaemia and anaemia of chronic disease at Ndola central hospital,Zambia.” 2017. Thesis, University of Zimbabwe. Accessed January 23, 2021.
http://dspace.unza.zm/handle/123456789/6331.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Chikwanda, Ephraim. “Evaluation of hepcidin as a potential biomaker for the differential diagnosis of iron deficiency anaemia and anaemia of chronic disease at Ndola central hospital,Zambia.” 2017. Web. 23 Jan 2021.
Vancouver:
Chikwanda E. Evaluation of hepcidin as a potential biomaker for the differential diagnosis of iron deficiency anaemia and anaemia of chronic disease at Ndola central hospital,Zambia. [Internet] [Thesis]. University of Zimbabwe; 2017. [cited 2021 Jan 23].
Available from: http://dspace.unza.zm/handle/123456789/6331.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Chikwanda E. Evaluation of hepcidin as a potential biomaker for the differential diagnosis of iron deficiency anaemia and anaemia of chronic disease at Ndola central hospital,Zambia. [Thesis]. University of Zimbabwe; 2017. Available from: http://dspace.unza.zm/handle/123456789/6331
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Hawaii – Manoa
9.
Hill, Brian Patrick.
Do current medical procedures sufficiently diagnose iron deficiency?.
Degree: 2015, University of Hawaii – Manoa
URL: http://hdl.handle.net/10125/100328
► M.S. University of Hawaii at Manoa 2014.
Iron deficiency is the most common nutrient deficiency throughout the world, including the United States. Although it has…
(more)
▼ M.S. University of Hawaii at Manoa 2014.
Iron deficiency is the most common nutrient deficiency throughout the world, including the United States. Although it has been known for over 125 years that symptomatic iron deficiency can exist in individuals despite normal levels of blood hemoglobin and red blood cell indices, current standards of medical practice frequently rely on measures of hemoglobin, hematocrit, mean corpuscular volume (MCV), and red blood cell distribution width (RDW) to screen for iron deficiency. The objective of this research is to determine how frequently iron deficient individuals are undiagnosed using hemoglobin, hematocrit, MCV, and RDW as indicators of iron status.
Data from eight National Health and Nutrition Examination Surveys (NHANES) studies (1976-2010) were included in the analysis. Males and females with data values for serum ferritin, hemoglobin, hematocrit, MCV, and RDW, not known to be pregnant or to have given birth within a year of data collection, were included in the analysis. Blood values from 56,000 individuals were stratified by study, gender, age and serum ferritin levels. Iron status was determined through the use of serum ferritin. Individuals were considered to be iron deficient and "missed" if adjusted serum ferritin was <21 ng/ml, but the levels of hemoglobin, hematocrit, MCV, and RDW were within normal ranges provided by the Centers for Disease Control and Prevention (CDC). Nonanemic iron deficiency (NAID) in various female age groups was missed 34% to 82% of the time. Younger males were missed for NAID 52% to 81% of the time, and males 40 years and older from 21% to 26% of the time. Therefore, screening for iron deficiency using hemoglobin, hematocrit, MCV and/or RDW fails to detect a significant portion of iron deficient individuals and can result both in delayed diagnosis and/or misdiagnosis that adversely affects the quality of life of the individual and incurs unnecessary medical costs.
Subjects/Keywords: nonanemic iron deficiency; ferritin; anemia; hemoglobin
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Hill, B. P. (2015). Do current medical procedures sufficiently diagnose iron deficiency?. (Thesis). University of Hawaii – Manoa. Retrieved from http://hdl.handle.net/10125/100328
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Hill, Brian Patrick. “Do current medical procedures sufficiently diagnose iron deficiency?.” 2015. Thesis, University of Hawaii – Manoa. Accessed January 23, 2021.
http://hdl.handle.net/10125/100328.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Hill, Brian Patrick. “Do current medical procedures sufficiently diagnose iron deficiency?.” 2015. Web. 23 Jan 2021.
Vancouver:
Hill BP. Do current medical procedures sufficiently diagnose iron deficiency?. [Internet] [Thesis]. University of Hawaii – Manoa; 2015. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/10125/100328.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Hill BP. Do current medical procedures sufficiently diagnose iron deficiency?. [Thesis]. University of Hawaii – Manoa; 2015. Available from: http://hdl.handle.net/10125/100328
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Helsinki
10.
Keskinen, Aurora.
Raskaudenaikaisen raudanpuuteanemian hoito suonensisäisellä rautalisällä.
Degree: Medicinska fakulteten, 2018, University of Helsinki
URL: http://hdl.handle.net/10138/235811
► Anemia koskettaa maailmanlaajuisesti jopa neljäsosaa väestöstä. Raskaana olevat naiset ovat erityisessä riskiryhmässä. Raudanpuutteen on arveltu liittyvän jopa 90 % raskausajan anemioista. Raudanpuuteanemialla on todettu yhteys…
(more)
▼ Anemia koskettaa maailmanlaajuisesti jopa neljäsosaa väestöstä. Raskaana olevat naiset ovat erityisessä riskiryhmässä. Raudanpuutteen on arveltu liittyvän jopa 90 % raskausajan anemioista. Raudanpuuteanemialla on todettu yhteys äitien ja lasten kuolleisuuteen, vastasyntyneen matalampaan syntymäpainoon, ennenaikaiseen synnytykseen sekä suurentuneeseen riskiin leikkaukselliselle synnytykselle, lisäksi raskaudenaikainen anemia saattaa lisätä riskiä lapsen anemialle vuoden ikään saakka. Raskaudenaikaista raudanpuuteanemiaa on jo pitkään hoidettu suun kautta otettavalla rautalisällä. Suun kautta otettava valmiste aiheuttaa osalle käyttäjistä merkittäviä sivuvaikutuksia eivätkä kaikki myöskään saa suun kautta otettavalla raudalla riittävää hoitovastetta. Uudet suonensisäiset rautavalmisteet on todettu turvallisiksi ja tehokkaiksi ja niihin liittyy vähemmän sivuvaikutuksia kuin suun kautta annosteltavaan rautaan.
Aineistomme käsitti 146 HYKS Naistenklinikan synnyttäjää, jotka olivat vuosina 2012 - 2017 saaneet suonensisäistä rautahoitoa ferrikarboksimaltoosilla (Ferinject®). Tarkoituksena oli kuvata aineiston synnyttäjät, raskaudet ja vastasyntyneet sekä selvittää Ferinjectin® mahdollisia sivuvaikutuksia ja vaikutusta laboratorioarvoihin.
Totesimme, että Ferinject® oli turvallinen valmiste eikä siihen liittynyt aineistossamme merkittäviä sivuvaikutuksia. Ferinject®-lääkkeen tehoa laboratorioarvoihin, kuten hemoglobiiniin, oli tässä aineistossa haastava arvioida, sillä kontrolliarvot oli otettu laajalla aikavälillä ja osalta tutkittavista ne puuttuivat kokonaan. Aineistossamme oli enemmän anemian riskitekijöitä kuin väestössä keskimäärin. Riskitekijöitä olivat esimerkiksi, että äiti oli uudelleensynnyttäjä tai että kyseessä oli monisikiöraskaus. Lisäksi keisarileikkauksia, ennenaikaisuutta ja istukan kiinnittymishäiriöitä tavattiin väestön keskimääräistä tasoa enemmän. Lasten myöhempää vointia ei tutkimuksemme puitteissa tulla seuraamaan.
Subjects/Keywords: pregnancy; iron deficiency anemia; ferric carboxymaltose; pregnancy; iron deficiency anemia; ferric carboxymaltose
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Keskinen, A. (2018). Raskaudenaikaisen raudanpuuteanemian hoito suonensisäisellä rautalisällä. (Masters Thesis). University of Helsinki. Retrieved from http://hdl.handle.net/10138/235811
Chicago Manual of Style (16th Edition):
Keskinen, Aurora. “Raskaudenaikaisen raudanpuuteanemian hoito suonensisäisellä rautalisällä.” 2018. Masters Thesis, University of Helsinki. Accessed January 23, 2021.
http://hdl.handle.net/10138/235811.
MLA Handbook (7th Edition):
Keskinen, Aurora. “Raskaudenaikaisen raudanpuuteanemian hoito suonensisäisellä rautalisällä.” 2018. Web. 23 Jan 2021.
Vancouver:
Keskinen A. Raskaudenaikaisen raudanpuuteanemian hoito suonensisäisellä rautalisällä. [Internet] [Masters thesis]. University of Helsinki; 2018. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/10138/235811.
Council of Science Editors:
Keskinen A. Raskaudenaikaisen raudanpuuteanemian hoito suonensisäisellä rautalisällä. [Masters Thesis]. University of Helsinki; 2018. Available from: http://hdl.handle.net/10138/235811
Aristotle University Of Thessaloniki (AUTH); Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ)
11.
Papageorgiou, Vaia.
Συσχέτιση πυρετικών σπασμών με την ύπαρξη σιδηροπενίας ή σιδηροπενικής αναιμίας στα παιδιά.
Degree: 2014, Aristotle University Of Thessaloniki (AUTH); Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ)
URL: http://hdl.handle.net/10442/hedi/36959
► Purpose: to perform recordings of the iron status of children with febrile seizures (FS) via evaluation of several laboratory tests and to investigate whether there…
(more)
▼ Purpose: to perform recordings of the iron status of children with febrile seizures (FS) via evaluation of several laboratory tests and to investigate whether there is any association between iron deficiency-iron deficiency anemia and FS.Material: This was a prospective case-control study including patients since March 2009 to March 2011. The sample of the study included children between 6 and 60 months and two groups were selected: 50 children with FS (patients) and 50 children with febrile illness without seizures (controls). The controls were matched to the cases by age and gender.Methods: For every participant of the survey a thorough clinical history was taken. The diagnosis of FS was made and they were defined as simple or complex. Blood samples were collected and hematological investigations were performed for hemoglobin concentration, hematocrit, MCV, RDW, serum iron, serum ferritin, TIBC, transferrin’s saturation and serum soluble transferrin receptors. An informed consent was obtained from parents or legal guardians of the children in order to participate.Results: The patients and controls were 25.6±13.2 and 25.1±14.2 months of mean age, respectively. Thirty-six (72%) of the cases had simple FS, twelve (24%) complex and 2 (4%) febrile status epilepticus. In 18 out of 50 cases (36%), there was positive history for FS. There were no statistical difference regarding gender, characteristics of personal history, obstetric-perinatal history and family history. We found, though, only a statistical difference in family history for FS (46% of cases vs 4% of controls, p<0.001). The mean levels of serum ferritin were significantly lower in cases (p: 0.02). The mean value of TIBC was significantly higher in cases (p: 0.04). The mean levels of hemoglobin were higher in cases but the difference failed to attain any statistical difference (p: 0.06). There were no other statistical significant differences between the cases and controls in the rest of laboratory testing. Regarding complex FS in particular, the mean levels of serum ferritin were significantly lower in cases than controls (p: 0.009). The mean value of TIBC was significantly higher in cases (p: 0.012). Iron deficiency was defined as level of serum ferritin ≤30 ng/ml, in terms of a febrile-infectious episode. A significantly higher proportion of cases (12/50 vs 2/50, p: 0,004) were iron deficient. Anemia was defined as hemoglobin concentration ≤10.5 g/dl for children 6-24 months and ≤11.5 g/dl for children older than 24 months. Iron deficiency anemia was more frequent among cases as compared to the controls (4% vs 2%), but the difference was not statistical significant (p: 0.54).Conclusions: Children with FS have lower levels of serum ferritin and higher levels of TIBC, suggesting an association between iron deficiency and FS. Especially, in complex FS the levels of serum ferritin were lower and levels of TIBC were higher, which verifies and reinforces our prime conclusion. Since iron deficiency seems to be related to the pathogenesis of FS, early prevention…
Subjects/Keywords: Πυρετικοί σπασμοί; Σίδηρος; Σιδηροπενία; Σιδηροπενική αναιμία; Febrile seizures; Iron; Iron deficiency; Iron deficiency anemia
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Papageorgiou, V. (2014). Συσχέτιση πυρετικών σπασμών με την ύπαρξη σιδηροπενίας ή σιδηροπενικής αναιμίας στα παιδιά. (Thesis). Aristotle University Of Thessaloniki (AUTH); Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ). Retrieved from http://hdl.handle.net/10442/hedi/36959
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Papageorgiou, Vaia. “Συσχέτιση πυρετικών σπασμών με την ύπαρξη σιδηροπενίας ή σιδηροπενικής αναιμίας στα παιδιά.” 2014. Thesis, Aristotle University Of Thessaloniki (AUTH); Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ). Accessed January 23, 2021.
http://hdl.handle.net/10442/hedi/36959.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Papageorgiou, Vaia. “Συσχέτιση πυρετικών σπασμών με την ύπαρξη σιδηροπενίας ή σιδηροπενικής αναιμίας στα παιδιά.” 2014. Web. 23 Jan 2021.
Vancouver:
Papageorgiou V. Συσχέτιση πυρετικών σπασμών με την ύπαρξη σιδηροπενίας ή σιδηροπενικής αναιμίας στα παιδιά. [Internet] [Thesis]. Aristotle University Of Thessaloniki (AUTH); Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ); 2014. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/10442/hedi/36959.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Papageorgiou V. Συσχέτιση πυρετικών σπασμών με την ύπαρξη σιδηροπενίας ή σιδηροπενικής αναιμίας στα παιδιά. [Thesis]. Aristotle University Of Thessaloniki (AUTH); Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ); 2014. Available from: http://hdl.handle.net/10442/hedi/36959
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
12.
Azevedo, Bernadete Aparecida Raimundo.
Consumo de ferro e orientação alimentar: uma análise envolvendo gestantes.
Degree: Mestrado, Nutrição em Saúde Pública, 2010, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/6/6138/tde-22102010-103507/
;
► Introdução: o período gestacional provoca alterações fisiológicas importantes para a mulher aumentando a necessidade de alguns micronutrientes, dentre eles, o ferro. A falta deste mineral…
(more)
▼ Introdução: o período gestacional provoca alterações fisiológicas importantes para a mulher aumentando a necessidade de alguns micronutrientes, dentre eles, o ferro. A falta deste mineral causa anemia ferropriva e conseqüências deletérias para o binômio mãe/concepto. A orientação nutricional pode ser um instrumento eficaz na redução desta carência. Objetivo: estimar o consumo de alimentos fontes de ferro incluindo os fortificados, identificar a percepção das gestantes em relação às causas e riscos da anemia na gestação e a participação do Programa Saúde da Família na orientação alimentar. Metodologia: o estudo foi realizado em São Caetano do Sul, com 109 gestantes atendidas pelo Programa de Pré-natal e beneficiadas pelo Programa Saúde da Família (PSF). A avaliação do consumo alimentar foi realizada utilizando-se o questionário de freqüência alimentar (QFA). Para avaliar a percepção das causas e riscos da anemia na gestação bem como da orientação alimentar utilizou-se questionário estruturado. Foi realizada análise exploratória dos dados por meio do cálculo de estatística descritiva e proporções. As análises estatísticas foram realizadas utilizando-se o software STATA versão 9.1. Resultados: o consumo per capita diário médio das carnes mais consumidas foi 33,74g (DP= 30,48) de carne bovina e 36,30g (DP= 26,20) de carne de frango. O pão mais consumido foi o francês, com consumo per capita diário médio de 53,51g (DP= 39,56). Quase todas as gestantes (93,58 por cento) desconhecem as causas e (86,24 por cento) desconhecem os riscos da anemia na gestação e a percepção de 91,74 por cento das mulheres é a de que não existe orientação alimentar no programa de atenção à gestante. Conclusões: o consumo alimentar das gestantes em relação aos alimentos fontes de ferro e aos fortificados com esse mineral mostrou-se insuficiente para atender à demanda e reduzir o risco decorrente da deficiência 8 de ferro. Para a redução da prevalência de anemia, a minoria recebeu orientação alimentar e a maioria desconhece as causas e conseqüências da deficiência de ferro na gestação
Introduction: The pregnance induces important physiological changes that lead to the increased need for some micronutrients like iron. The lack of this mineral causes anemia and deleterious consequences for both the mother and fetus. Nutritional counseling can be an effective tool in reducing anemia occurence. Objective: To estimate the intake of food sources of iron including fortified, identify the perception of women regarding the causes and risks of anemia in pregnancy and determine the direction of the Program Health Family in nutritional orientation. Methods: The study was conducted in Sao Caetano do Sul, with 109 pregnant women attending the Prenatal Program and benefit from the Family Health Program (PSF). The dietary intake assessment was performed using the food frequency questionnaire (FFQ). To assess the perception of the causes and risks of anemia in pregnancy as well as nutritional guidance, we used a structured questionnaire. We performed exploratory…
Advisors/Committee Members: Szarfarc, Sophia Cornbluth.
Subjects/Keywords: Anemia Ferropriva; Consumo Alimentar; Food Intake; Gestantes; Iron Deficiency Anemia; Pregnant
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Azevedo, B. A. R. (2010). Consumo de ferro e orientação alimentar: uma análise envolvendo gestantes. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/6/6138/tde-22102010-103507/ ;
Chicago Manual of Style (16th Edition):
Azevedo, Bernadete Aparecida Raimundo. “Consumo de ferro e orientação alimentar: uma análise envolvendo gestantes.” 2010. Masters Thesis, University of São Paulo. Accessed January 23, 2021.
http://www.teses.usp.br/teses/disponiveis/6/6138/tde-22102010-103507/ ;.
MLA Handbook (7th Edition):
Azevedo, Bernadete Aparecida Raimundo. “Consumo de ferro e orientação alimentar: uma análise envolvendo gestantes.” 2010. Web. 23 Jan 2021.
Vancouver:
Azevedo BAR. Consumo de ferro e orientação alimentar: uma análise envolvendo gestantes. [Internet] [Masters thesis]. University of São Paulo; 2010. [cited 2021 Jan 23].
Available from: http://www.teses.usp.br/teses/disponiveis/6/6138/tde-22102010-103507/ ;.
Council of Science Editors:
Azevedo BAR. Consumo de ferro e orientação alimentar: uma análise envolvendo gestantes. [Masters Thesis]. University of São Paulo; 2010. Available from: http://www.teses.usp.br/teses/disponiveis/6/6138/tde-22102010-103507/ ;
University of Toronto
13.
Khan, Waqas Ullah.
Controlling Iron Defeciency Anemia and Preventing Calcium Deficiency in Bangladesh Children: A Novel Approach Using a Multi-micronutrient Powder (MNP) Formulation.
Degree: 2011, University of Toronto
URL: http://hdl.handle.net/1807/29576
► Iron deficiency anemia (IDA) and calcium deficiency affect millions of children globally. Sprinkles is a multi-micronutrient powder (MNP) that has successfully treated anemic infants and…
(more)
▼ Iron deficiency anemia (IDA) and calcium deficiency affect millions of children globally. Sprinkles is a multi-micronutrient powder (MNP) that has successfully treated anemic infants and can be modified to include additional micronutrients. The efficacy for treating IDA and preventing calcium deficiency requires evaluation due to potential nutrient interactions. We assessed the efficacy of Sprinkles MNP including iron with and without calcium on hemoglobin (Hb) response in 100 anemic rural Bangladeshi infants for 2 months. Sprinkles MNP with and without calcium resulted in a significantly higher Hb concentrations in both groups (P<0.0001 and P<0.0001). However, infants who received Sprinkles MNP without calcium had a significantly higher change in Hb concentration (P=0.024) and rate of recovery from anemia (P=0.008). No differences in socio-demographic or dietary characteristics were documented between groups. Although both groups had an improvement in Hb status, the antagonistic interaction between iron and calcium requires further study.
MAST
Advisors/Committee Members: Zlotkin, Stanley H., Nutritional Sciences.
Subjects/Keywords: Iron Deficiency Anemia; Calcium Deficiency; Nutrient-Nutrient Interaction; Micronutrient Powder; 0570
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Khan, W. U. (2011). Controlling Iron Defeciency Anemia and Preventing Calcium Deficiency in Bangladesh Children: A Novel Approach Using a Multi-micronutrient Powder (MNP) Formulation. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/29576
Chicago Manual of Style (16th Edition):
Khan, Waqas Ullah. “Controlling Iron Defeciency Anemia and Preventing Calcium Deficiency in Bangladesh Children: A Novel Approach Using a Multi-micronutrient Powder (MNP) Formulation.” 2011. Masters Thesis, University of Toronto. Accessed January 23, 2021.
http://hdl.handle.net/1807/29576.
MLA Handbook (7th Edition):
Khan, Waqas Ullah. “Controlling Iron Defeciency Anemia and Preventing Calcium Deficiency in Bangladesh Children: A Novel Approach Using a Multi-micronutrient Powder (MNP) Formulation.” 2011. Web. 23 Jan 2021.
Vancouver:
Khan WU. Controlling Iron Defeciency Anemia and Preventing Calcium Deficiency in Bangladesh Children: A Novel Approach Using a Multi-micronutrient Powder (MNP) Formulation. [Internet] [Masters thesis]. University of Toronto; 2011. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/1807/29576.
Council of Science Editors:
Khan WU. Controlling Iron Defeciency Anemia and Preventing Calcium Deficiency in Bangladesh Children: A Novel Approach Using a Multi-micronutrient Powder (MNP) Formulation. [Masters Thesis]. University of Toronto; 2011. Available from: http://hdl.handle.net/1807/29576
14.
Stulbach, Tamara Eugenia.
Avaliação do programa nacional de suplementação de ferro no controle de anemia, em crianças de 6 a 24 meses, assistidas nos centros de educação infantil do município do Guarujá.
Degree: PhD, Nutrição, 2009, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/6/6133/tde-16012009-155209/
;
► Introdução: A anemia por deficiência de ferro em crianças é um dos maiores problemas nutricionais enfrentados pelos países em desenvolvimento. O Programa Nacional de Suplementação…
(more)
▼ Introdução: A
anemia por deficiência de ferro em crianças é um dos maiores problemas nutricionais enfrentados pelos países em desenvolvimento. O Programa Nacional de Suplementação de Ferro instituído no Brasil em 2005, que visa o controle dessa deficiência nutricional, consiste na suplementação semanal, com sulfato ferroso, distribuído gratuitamente nos postos de saúde, a crianças de 6 a 18 meses. Objetivo: verificar a efetividade do Programa Nacional de Suplementação de Ferro no controle da
anemia ferropriva, em lactentes atendidos nas creches municipais do Guarujá. Metodologia: O trabalho foi autorizado pelas Secretarias Municipais de Saúde e Educação do município e teve o consentimento livre e esclarecido dos responsáveis pelas crianças.Os responsáveis responderam no início do estudo a um questionário sobre as características sociais, econômicas e hábitos alimentares da família.Todas as crianças entre 6 e 24 meses de idade, durante um período de 24 semanas, receberam doses semanais de sulfato ferroso conforme às recomendações propostas pelo Programa Nacional de Suplementação de Ferro.As crianças foram avaliadas quanto à prevalência da
anemia e o sucesso da intervenção que foi determinado pelos valores de concentração da hemoglobina no início e após o período de intervenção. Resultados: Participaram do estudo 136 crianças. A maioria das famílias (64%) recebia menos de 2 salários mínimos e 58% delas declararam ser a mãe o chefe da casa. A escolaridade foi definida considerando anos completos de estudo e 46,3% estudou por 8 anos ou mais. O estado nutricional das crianças foi avaliado pelas curvas de referência da OMS (2006) e CDC (2000). Verificou-se que, independente da referência utilizada as crianças apresentaram percentual importante de déficit estatural e de sobrepeso. Pelo padrão da OMS (2006), 30,8% das crianças foram diagnosticadas com baixa estatura, enquanto pelo CDC (2000) a prevalência foi de 18%. O sobrepeso foi observado em 24% pela OMS (2006) e 18% pelo CDC (2000). A prevalência de
anemia no início do estudo foi de 39% e de 30,8% no final do período de intervenção. Entre as crianças inicialmente anêmicas foi observado um aumento médio da concentração de hemoglobina de 1,19g/dL ( p = 0,000). Independente do estado inicial da criança a intervenção foi eficaz na redução da
anemia. A alimentação no domicílio mostrou-se bem semelhante àquela oferecida na creche. A presença de alimentos fontes de ferro natural e/ou fortificados foi observada em todas as refeições, mas, mesmo assim, a ingestão dietética do nutriente em pauta não atingiu a quantidade recomendada para atender a necessidade dos lactentes. Sendo assim a suplementação profilática oferecida pelo Programa Nacional de Suplementação de Ferro é fundamental para atender à demanda do mineral e assim permitir o adequado desenvolvimento dos menores de 2 anos. Conclusão: Sendo os lactentes um grupo de risco para a deficiência de ferro e considerando as inúmeras conseqüências deletérias acarretadas por essa carência nutricional o Programa Nacional de…
Advisors/Committee Members: Szarfarc, Sophia Cornbluth.
Subjects/Keywords: Anemia; Anemia Ferropriva; Ferro; Infants; Iron; Iron-Deficiency; Lactentes; Sulfato Ferroso; Suplementação; Supplementation
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Stulbach, T. E. (2009). Avaliação do programa nacional de suplementação de ferro no controle de anemia, em crianças de 6 a 24 meses, assistidas nos centros de educação infantil do município do Guarujá. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/6/6133/tde-16012009-155209/ ;
Chicago Manual of Style (16th Edition):
Stulbach, Tamara Eugenia. “Avaliação do programa nacional de suplementação de ferro no controle de anemia, em crianças de 6 a 24 meses, assistidas nos centros de educação infantil do município do Guarujá.” 2009. Doctoral Dissertation, University of São Paulo. Accessed January 23, 2021.
http://www.teses.usp.br/teses/disponiveis/6/6133/tde-16012009-155209/ ;.
MLA Handbook (7th Edition):
Stulbach, Tamara Eugenia. “Avaliação do programa nacional de suplementação de ferro no controle de anemia, em crianças de 6 a 24 meses, assistidas nos centros de educação infantil do município do Guarujá.” 2009. Web. 23 Jan 2021.
Vancouver:
Stulbach TE. Avaliação do programa nacional de suplementação de ferro no controle de anemia, em crianças de 6 a 24 meses, assistidas nos centros de educação infantil do município do Guarujá. [Internet] [Doctoral dissertation]. University of São Paulo; 2009. [cited 2021 Jan 23].
Available from: http://www.teses.usp.br/teses/disponiveis/6/6133/tde-16012009-155209/ ;.
Council of Science Editors:
Stulbach TE. Avaliação do programa nacional de suplementação de ferro no controle de anemia, em crianças de 6 a 24 meses, assistidas nos centros de educação infantil do município do Guarujá. [Doctoral Dissertation]. University of São Paulo; 2009. Available from: http://www.teses.usp.br/teses/disponiveis/6/6133/tde-16012009-155209/ ;
Boston University
15.
Lyons, Christopher Kyle.
Active management of iron deficiency anemia in patients with inflammatory bowel disease.
Degree: MS, Medical Sciences, 2019, Boston University
URL: http://hdl.handle.net/2144/36587
► Iron deficiency anemia (IDA) is a common extra-intestinal manifestation of inflammatory bowel disease (IBD). It is particularly common in the pediatric population, with 40-60% of…
(more)
▼ Iron deficiency anemia (IDA) is a common extra-intestinal manifestation of inflammatory bowel disease (IBD). It is particularly common in the pediatric population, with 40-60% of pediatric patients with IBD meeting criteria for
anemia (Aljomah et al, 2018). A number of studies have examined the use of both IV and oral
iron treatments to treat
anemia in IBD, but few have examined the safety and efficacy of these treatments in children and how they impact a patient’s health-related quality of life. We conducted a prospective cohort study of 79 pediatric patients admitted to Boston Children’s Hospital for management of their IBD. 48 of these patients received IV
iron, 13 received oral
iron, and 12 were not treated with either. Treatment with IV
iron resulted in a statistically significant increase in hemoglobin of 1.75g/dL+/-1.4g/dL (mean +/- SD) from admission to the time of their first post-discharge visit (p=0.0001). Prescription of oral
iron at the time of discharge did not result in a significant increase in hemoglobin over the same interval (p=0.481). Though there was a positive trend, IV
iron treatment did not result in a significant change in health-related quality of life (HRQOL) measurements as measured by the IMPACT-III questionnaire (p=0.06). Our study suggests that IDA is common in patients admitted for management of their IBD, IV
iron is more efficacious in raising hemoglobin, and that larger studies will be needed to more fully demonstrate the impact of effective
iron repletion on overall quality of life in these patients.
Advisors/Committee Members: Young, Aaron W. (advisor), Rufo, Paul A. (advisor).
Subjects/Keywords: Medicine; Inflammatory bowel disease; Iron deficiency anemia; IV iron; Pediatric IBD
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Lyons, C. K. (2019). Active management of iron deficiency anemia in patients with inflammatory bowel disease. (Masters Thesis). Boston University. Retrieved from http://hdl.handle.net/2144/36587
Chicago Manual of Style (16th Edition):
Lyons, Christopher Kyle. “Active management of iron deficiency anemia in patients with inflammatory bowel disease.” 2019. Masters Thesis, Boston University. Accessed January 23, 2021.
http://hdl.handle.net/2144/36587.
MLA Handbook (7th Edition):
Lyons, Christopher Kyle. “Active management of iron deficiency anemia in patients with inflammatory bowel disease.” 2019. Web. 23 Jan 2021.
Vancouver:
Lyons CK. Active management of iron deficiency anemia in patients with inflammatory bowel disease. [Internet] [Masters thesis]. Boston University; 2019. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/2144/36587.
Council of Science Editors:
Lyons CK. Active management of iron deficiency anemia in patients with inflammatory bowel disease. [Masters Thesis]. Boston University; 2019. Available from: http://hdl.handle.net/2144/36587
Boston University
16.
Spaan, Jonathan.
Treatment of iron deficiency in pediatric patients with inflammatory bowel disease.
Degree: MS, Medical Sciences, 2020, Boston University
URL: http://hdl.handle.net/2144/41370
► Iron deficiency anemia (IDA) is the most common extraintestinal complication encountered in patients with Inflammatory Bowel Disease (IBD), and it is more prevalent in pediatric…
(more)
▼ Iron deficiency anemia (IDA) is the most common extraintestinal complication encountered in patients with Inflammatory Bowel Disease (IBD), and it is more prevalent in pediatric patients compared to adults (Rogler and Vavricka). The inflammation and blood loss from the disease impacts both the absorption and storage of
iron in the body (Rogler and Vavricka). With the intent of establishing a standard of care for IDA treatment in patients with IBD, we conducted a prospective study of 104 consecutive pediatric patients to assess the safety and efficacy of intravenous (IV)
iron therapy compared to oral therapy and no treatment, as well as the effects of
iron therapy on patient quality of life. Efficacy was assessed by comparing the change in hemoglobin levels in the interval between admission to outpatient follow-up. The average time to the first ambulatory follow-up was 29.08 days. 69 patients received IV
iron therapy, 17 patients received oral
iron supplementation, and 18 patients had no treatment. Treatment with IV
iron resulted in a statistically significant increase in hemoglobin levels (2.00 g/dL ± 1.57 g/dL, as mean ± standard deviation) from admission to the first follow-up ambulatory appointment (p < .0001). Patients receiving IV
iron therapy also experienced a significantly greater mean increase in hemoglobin levels than those treated with oral
iron (p = .0084) or no treatment (p = .0018). Further, patients treated with IV
iron experienced a significant increase in their quality of life at follow-up compared to admission as measured by the Impact-III questionnaire (p = .0179). Our study illustrates the importance of screening pediatric patients with IBD for IDA and suggests that IV
iron treatment is safe and more effective in raising hematologic and
iron measures than orally- administered alternative options.
Advisors/Committee Members: Stearns-Kurosawa, Deborah J. (advisor).
Subjects/Keywords: Medicine; Inflammatory bowel disease; Iron; Iron deficiency anemia
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Spaan, J. (2020). Treatment of iron deficiency in pediatric patients with inflammatory bowel disease. (Masters Thesis). Boston University. Retrieved from http://hdl.handle.net/2144/41370
Chicago Manual of Style (16th Edition):
Spaan, Jonathan. “Treatment of iron deficiency in pediatric patients with inflammatory bowel disease.” 2020. Masters Thesis, Boston University. Accessed January 23, 2021.
http://hdl.handle.net/2144/41370.
MLA Handbook (7th Edition):
Spaan, Jonathan. “Treatment of iron deficiency in pediatric patients with inflammatory bowel disease.” 2020. Web. 23 Jan 2021.
Vancouver:
Spaan J. Treatment of iron deficiency in pediatric patients with inflammatory bowel disease. [Internet] [Masters thesis]. Boston University; 2020. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/2144/41370.
Council of Science Editors:
Spaan J. Treatment of iron deficiency in pediatric patients with inflammatory bowel disease. [Masters Thesis]. Boston University; 2020. Available from: http://hdl.handle.net/2144/41370
University of KwaZulu-Natal
17.
Mkhize, Princess Zinhle.
Adherence to iron prophylactic therapy during pregnancy in an urban regional hospital in Durban, South Africa.
Degree: 2017, University of KwaZulu-Natal
URL: http://hdl.handle.net/10413/16034
► Iron and folic acid supplementation plays a major role in prevention and control of iron deficiency anaemia in antenatal care. In South Africa, although all…
(more)
▼ Iron and folic acid supplementation plays a major role in prevention and control of
iron deficiency anaemia
in antenatal care. In South Africa, although all pregnant women receive
iron, folate and calcium
supplementation throughout pregnancy, anaemia is still common. Low adherence may be a key contributor
to the ineffectiveness of supplementation programs.Therefore, this study was conducted to examine
adherence to prophylactic
iron supplementation during the antenatal period. An observational clinical study
was conducted in a regional hospital from January- December 2016. Women (n=100 HIV uninfected and
n=100 HIV infected) were recruited and subdivided into three groups: (a) 1st attendees ≤ 34 weeks (n=33),
(b) 34-36 weeks (n =34) and (c) ≥ 37 weeks /birth (n=33) respectively. A structured questionnaire was used
for data collection.
Data were coded and computed onto an excel sheet for statistical analysis using SPSS software.
Data from women (n = 24) from 1st visit attendees ≤ 34 weeks and 34-36 weeks subgroups indicated that
pill count and self-reported data reflected 50% adherence and 46% non-adherence, being higher in the HIV
infected women (75%). Nausea was the commonest side effect in all trimesters (79, 2%). Adherence
(27.8%) and non-adherence (72.1%) to
iron, folic acid and calcium supplementation were observed in 176
(88%) women.
Promoting essential strategies on the importance of consumption and effectiveness of
iron prophylactic
therapy is essential to maintain and improve anaemia in antenatal attendees during pregnancy.
Advisors/Committee Members: Moodley, Jagidesa. (advisor), Naicker, Thajasvarie. (advisor).
Subjects/Keywords: Iron prophylactic therapy.; Iron deficiency anaemia.; Adhere to prophylactic iron.; Anemia in antenatal.; Prophylectic iron.
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mkhize, P. Z. (2017). Adherence to iron prophylactic therapy during pregnancy in an urban regional hospital in Durban, South Africa. (Thesis). University of KwaZulu-Natal. Retrieved from http://hdl.handle.net/10413/16034
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Mkhize, Princess Zinhle. “Adherence to iron prophylactic therapy during pregnancy in an urban regional hospital in Durban, South Africa.” 2017. Thesis, University of KwaZulu-Natal. Accessed January 23, 2021.
http://hdl.handle.net/10413/16034.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Mkhize, Princess Zinhle. “Adherence to iron prophylactic therapy during pregnancy in an urban regional hospital in Durban, South Africa.” 2017. Web. 23 Jan 2021.
Vancouver:
Mkhize PZ. Adherence to iron prophylactic therapy during pregnancy in an urban regional hospital in Durban, South Africa. [Internet] [Thesis]. University of KwaZulu-Natal; 2017. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/10413/16034.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Mkhize PZ. Adherence to iron prophylactic therapy during pregnancy in an urban regional hospital in Durban, South Africa. [Thesis]. University of KwaZulu-Natal; 2017. Available from: http://hdl.handle.net/10413/16034
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Florida
18.
Gulec, Sukru.
Physiological Role of Intestinal Copper Transporter Atp7a in Iron Metabolism.
Degree: PhD, Nutritional Sciences, 2013, University of Florida
URL: https://ufdc.ufl.edu/UFE0045306
► The Menkes Copper-Transporting ATPase(Atp7a) is an intestinal copper (Cu) transporter that is essential for assimilation of dietary Cu. Studies showed that Atp7a is induced in…
(more)
▼ The Menkes Copper-Transporting ATPase(Atp7a) is an intestinal copper (Cu) transporter that is essential for assimilation of dietary Cu. Studies showed that Atp7a is induced in the rodent intestine during
iron (Fe)
deficiency, when serum and liver Cu levels increase. Thus, to test the hypothesis that Atp7a is important for Fe absorption and maintain Fe balance in body during Fe
deficiency, I initiated an investigation in Atp7a mutant (Brindled) male mice. Brindled mice express mutant form of Atp7a with reduced function. Because mutant mice die perinatally of severe Cu
deficiency, Cu was administered intraperitoneally at 7 and 9 days-of-age. After 3 month recovery period, rescued mutant mice and wild-type litter mates were deprived of dietary Fe for 3 weeks, and Fe homeostasis was studied. Results showed that Brindled mice were able to appropriately regulate Fe absorption in response to Fe deprivation; however,unlike the situation in wild-type litter mates, subsequent changes in intestinal and liver Cu levels in the mutants may have been necessary to support Fe homeostasis. An essential role for Atp7a in Fe absorption in these mice was thus not clearly identified, but possible residual Atp7a function and the complex Fe - and Cu -deficient phenotype of the mutant mice complicated data interpretation. Next, I evaluated a possible role for Atp7a in Fe absorption by developing Atp7a knock down (KD) rat intestinal epithelial (IEC-6) cells using shRNA technology. In Atp7a KD cells, Cu loading increased intracellular Cu levels, consistent with defective Cu export function of Atp7a. Expression of Fe transport-related genes was altered in KD cells. Expression of hephaestin (Heph), ferroxidase important for Fe export from intestine, was strongly repressed in KD cells.Heph down regulation was associated with a reduction in ferroxidase activity in KD cells. Conversely, expression of ferroportin 1 (Fpn1), basolateral Fe exporter,increased in KD cells. Importantly, increased Fpn1 expression correlated with enhanced transepithelial Fe transport observed in the Atp7a KD cells. This increase in transport suggested a minimal role for Heph in Fe absorption. Atp7asilencing thus altered Fe flux, suggesting that Atp7a function or intracellular Cu levels are important to maintain cellular Fe homeostasis. ( en )
Advisors/Committee Members: Collins, James Forrest (committee chair), Knutson, Mitchell D (committee member), Cousins, Robert J (committee member), Stevens, Bruce R (committee member), Vidyasagar, Sadasivan (committee member).
Subjects/Keywords: Dietary iron; Enterocytes; Homeostasis; Iron; Iron absorption; Iron deficiency anemia; Liver; Messenger RNA; Metabolism; Rats; absorption – atp7a – copper – deficiency – intestinal – iron
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Gulec, S. (2013). Physiological Role of Intestinal Copper Transporter Atp7a in Iron Metabolism. (Doctoral Dissertation). University of Florida. Retrieved from https://ufdc.ufl.edu/UFE0045306
Chicago Manual of Style (16th Edition):
Gulec, Sukru. “Physiological Role of Intestinal Copper Transporter Atp7a in Iron Metabolism.” 2013. Doctoral Dissertation, University of Florida. Accessed January 23, 2021.
https://ufdc.ufl.edu/UFE0045306.
MLA Handbook (7th Edition):
Gulec, Sukru. “Physiological Role of Intestinal Copper Transporter Atp7a in Iron Metabolism.” 2013. Web. 23 Jan 2021.
Vancouver:
Gulec S. Physiological Role of Intestinal Copper Transporter Atp7a in Iron Metabolism. [Internet] [Doctoral dissertation]. University of Florida; 2013. [cited 2021 Jan 23].
Available from: https://ufdc.ufl.edu/UFE0045306.
Council of Science Editors:
Gulec S. Physiological Role of Intestinal Copper Transporter Atp7a in Iron Metabolism. [Doctoral Dissertation]. University of Florida; 2013. Available from: https://ufdc.ufl.edu/UFE0045306
University of Florida
19.
Jiang, Lingli.
The role of Dmt1 in the copper-related compensatory response of the intestinal epithelium during iron-deficiency.
Degree: PhD, Nutritional Sciences, 2013, University of Florida
URL: https://ufdc.ufl.edu/UFE0045156
► Many human and animal studies have shown that serum and liver copper levels increase during iron deficiency. In addition, divalent metal transporter 1 (Dmt1) and…
(more)
▼ Many human and animal studies have shown that serum and liver copper levels increase during
iron deficiency. In addition, divalent metal transporter 1 (Dmt1) and the Menkes copper-transporting ATPase (Atp7a) are strongly up-regulated in the duodenum of
iron-deficient rats. These findings suggest an important interaction between
iron (Fe) and copper (Cu) during
iron deficiency. The hypothesis that Dmt1 is necessary for alterations in the expression/activity of copper-related proteins during
iron deficiency was tested. Experiments were performed in the Belgrade (b) rat model of genetic
iron deficiency. Dmt1 and Atp7a mRNA expression, along with other metal homeostasis- related genes (e.g. Tfr1), was increased in enterocytes from b/b rats (as compared to +/b rats), while hephaestin (Heph) did not change. In the liver, Cp mRNA expression was unaltered. Immunoblots demonstrated that Atp7a protein expression increased in the b/b rats, along with duodenal Heph protein expression (transports copper during low-
iron states, when it is strongly induced, and competing
iron atoms are low in abundance. First, the Belgrade rat model was utilized to show that mutated Dmt1 cannot increase copper transport in the
iron-deficient b/b rats, but the +/b rats did show changes in copper levels during
iron deficiency. To further explore the possible copper transport by Dmt1, a doxycycline (DOX) inducible Dmt1 over-expression system in HEK-293 cells was employed. In DOX-treated cells with confirmed Dmt1 over-expression, 64Cu uptake was not different from untreated cells. However, a significant increase in copper uptake was noted (~3 fold) when cells were treated with DOX in the presence of an
iron chelator (as compared to DOX only-treated cells). It is therefore concluded that under normal conditions, Dmt1 does not transport copper, but that it may be involved in copper transport under low-
iron conditions. ( en )
Advisors/Committee Members: Collins, James Forrest (committee chair), Knutson, Mitchell D (committee member), Sitren, Harry S (committee member), Clanton, Thomas Lindsay (committee member).
Subjects/Keywords: Anemia; Dietary iron; Enterocytes; Iron; Iron deficiency anemia; Liver; Messenger RNA; Metabolism; Rats; Street performers; belgrade – copper – dmt1 – iron – transport
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Jiang, L. (2013). The role of Dmt1 in the copper-related compensatory response of the intestinal epithelium during iron-deficiency. (Doctoral Dissertation). University of Florida. Retrieved from https://ufdc.ufl.edu/UFE0045156
Chicago Manual of Style (16th Edition):
Jiang, Lingli. “The role of Dmt1 in the copper-related compensatory response of the intestinal epithelium during iron-deficiency.” 2013. Doctoral Dissertation, University of Florida. Accessed January 23, 2021.
https://ufdc.ufl.edu/UFE0045156.
MLA Handbook (7th Edition):
Jiang, Lingli. “The role of Dmt1 in the copper-related compensatory response of the intestinal epithelium during iron-deficiency.” 2013. Web. 23 Jan 2021.
Vancouver:
Jiang L. The role of Dmt1 in the copper-related compensatory response of the intestinal epithelium during iron-deficiency. [Internet] [Doctoral dissertation]. University of Florida; 2013. [cited 2021 Jan 23].
Available from: https://ufdc.ufl.edu/UFE0045156.
Council of Science Editors:
Jiang L. The role of Dmt1 in the copper-related compensatory response of the intestinal epithelium during iron-deficiency. [Doctoral Dissertation]. University of Florida; 2013. Available from: https://ufdc.ufl.edu/UFE0045156
20.
Tavares, Cristiane Fernandes de Freitas.
Estudo dos principais fatores que contribuem para o desenvolvimento das anemias hipocrômicas microcíticas em crianças na fase escolar.
Degree: PhD, Biociências Aplicadas à Farmácia, 2011, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/60/60135/tde-28032012-151617/
;
► Varios fatores contribuem para o desenvolvimento da anemia, que constitui um dos mais graves problemas de saude publica. A anemia hipocromica microcitica e a forma…
(more)
▼ Varios fatores contribuem para o desenvolvimento da
anemia, que constitui um dos mais graves problemas de saude publica. A
anemia hipocromica microcitica e a forma mais comum em criancas e adolescentes. Dentre as causas desta
anemia estao: a) deficiencia de ferro, que resulta de um longo periodo do balanco negativo do micronutriente e causa retardo no crescimento e comprometimento do desempenho cognitivo de criancas; b) contaminacao por chumbo (plumbismo) que tambem afeta o desenvolvimento das criancas, podendo ser agravada nos portadores de polimorfismo da enzima ALAD; c) hemoglobinopatias (hemoglobinas variantes e talassemias), anemias herdadas que afetam 7% da populacao mundial. Devido a alta prevalencia destas patologias, o presente trabalho teve como objetivo estudar um grupo de criancas de escolas publicas, identificando os fatores que contribuem para o desenvolvimento de anemias hipocromicas microciticas e estabelecer relacoes entre as caracteristicas laboratoriais das doencas. Participaram do estudo 427 criancas, com idade entre 6 a 9 anos, sendo 235 do sexo feminino e 192 do sexo masculino, alunos de Escolas Municipais e Estaduais, da zona norte da cidade de Ribeirao Preto-SP. Foram analisados: a) numero global de eritrocitos e leucocitos, concentracao de hemoglobina, hematocrito, indices hematimetricos e distribuicao da amplitude das celulas vermelhas (contador automatico Micros 45 . Horiba ABXR) e calculo do indice matematico RDWI; b) niveis plasmaticos de chumbo (espectrometro de massa com plasma indutivamente acoplado VG Plasmaquad PQIIR) e estudo das delecoes dos polimorfismos da enzima ALAD, por PCR; c) status ferrico pelos niveis de ferritina serica (imunoquimioluminescencia utilizando kit Ferritin Immulite . DPCR e equipamento Immulite 1 - DPCR), receptor de transferrina soluvel (ensaio imunoenzimatico, utilizando o kit Quantikine soluble transferrin receptor da R&D SystemsR e o leitor de microplacas de ELISA READER 210, modelo Microwell System Organon TeknikaR) e calculo do indice sTfR/log ferritina; d) analise das hemoglobinas por eletroforese em acetato de celulose, pH alcalino, por HPLC (sistema automatizado Variant II Bio-RadR e kit gÀ-talassemia Short Program) e PCR para a principal delecao de ¿- talassemias. Com base no criterio recomendado pela OMS para definir
anemia (Hb menor que 11,5 g/dL), verificou-se que 75 (17,6%) criancas eram anemicas, sendo 33 (44%) portadoras de algum tipo de hemoglobinopatia, 29 (38,6%) com anemias de causa desconhecida e 13 (17,4%) com
anemia por deficiencia de ferro. Das anemias, apenas 14 eram anemias hipocromicas microciticas, sendo que 10 (71,4%) eram algum tipo de hemoglobinopatia, 2 (14,2%) ADF e 2 (14,2%) de causa desconhecida. Na populacao estudada, a prevalencia de hemoglobinopatias foi de 16,6% , a saber: 11,6% com ¿-talassemia; 4% com aumento de Hb F; 3,5% com Hb AS; 2,8% com À-talassemia; 0,96% com ¿/À-talassemia e 0,24% com Hb AC. Os niveis de chumbo plasmatico, em todos os participantes do estudo, estavam dentro do recomendado pelo Center for…
Advisors/Committee Members: Souza, Ana Maria de.
Subjects/Keywords: Anemia hipocrômica microcítica; Anemia por deficiência de ferro.; Hemoglobinopathies; Hemoglobinopatias; Hypochromic microcytic anemia; Iron deficiency anemia; Lead poisoning; Plumbismo
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Tavares, C. F. d. F. (2011). Estudo dos principais fatores que contribuem para o desenvolvimento das anemias hipocrômicas microcíticas em crianças na fase escolar. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/60/60135/tde-28032012-151617/ ;
Chicago Manual of Style (16th Edition):
Tavares, Cristiane Fernandes de Freitas. “Estudo dos principais fatores que contribuem para o desenvolvimento das anemias hipocrômicas microcíticas em crianças na fase escolar.” 2011. Doctoral Dissertation, University of São Paulo. Accessed January 23, 2021.
http://www.teses.usp.br/teses/disponiveis/60/60135/tde-28032012-151617/ ;.
MLA Handbook (7th Edition):
Tavares, Cristiane Fernandes de Freitas. “Estudo dos principais fatores que contribuem para o desenvolvimento das anemias hipocrômicas microcíticas em crianças na fase escolar.” 2011. Web. 23 Jan 2021.
Vancouver:
Tavares CFdF. Estudo dos principais fatores que contribuem para o desenvolvimento das anemias hipocrômicas microcíticas em crianças na fase escolar. [Internet] [Doctoral dissertation]. University of São Paulo; 2011. [cited 2021 Jan 23].
Available from: http://www.teses.usp.br/teses/disponiveis/60/60135/tde-28032012-151617/ ;.
Council of Science Editors:
Tavares CFdF. Estudo dos principais fatores que contribuem para o desenvolvimento das anemias hipocrômicas microcíticas em crianças na fase escolar. [Doctoral Dissertation]. University of São Paulo; 2011. Available from: http://www.teses.usp.br/teses/disponiveis/60/60135/tde-28032012-151617/ ;
Massey University
21.
Kafa, Rosemary I'ilu.
Iron status and factors influencing iron status of Solomon Islands women living in New Zealand : a thesis presented in the partial fulfillment of the requirements for the degree of Masters of Science (Human Nutrition), Massey University, Albany, New Zealand
.
Degree: 2012, Massey University
URL: http://hdl.handle.net/10179/4718
► Iron deficiency is a global problem among women of reproductive age, particularly in developing countries. A recent survey from the Solomon Islands reported that 44%…
(more)
▼ Iron deficiency is a global problem among women of reproductive age, particularly in developing countries. A recent survey from the Solomon Islands reported that 44% of women of reproductive aged were anaemic. Currently nothing is known about the iron status of women from the Solomon Islands living in New Zealand (NZ).
Aim:
This study aims to assess and compare iron status and factors influencing iron status of Solomon Islands with Caucasian women living in and around Auckland, NZ.
Methods:
This was a cross-sectional study comparing 40 Solomon Islands women with 80 age-matched Caucasian women living in and around Auckland. Serum ferritin (SF), C-reactive protein (CRP) and haemoglobin (Hb) were analyzed. Iron status was defined as: iron replete (SF > 20 µg/L + Hb > 120 g/L), iron deficiency (ID) (SF < 20 µg/L + Hb > 120 g/L) and iron deficiency anaemia (IDA) (SF < 20 µg/L + Hb < 120 g/L). Participants with CRP >10 mg/L were excluded from this study. Dietary assessment was conducted using a computerised iron food frequency questionnaire including questions on dietary habits, purposely to assess foods affecting iron status. In addition, a 24-hour dietary recall was used to assess the average daily nutrient intake of Solomon Islands women. Demographic and body composition data were also collected together with data on other factors affecting iron status such as blood loss and general health history.
Results:
No significant difference in the prevalence of low iron stores + IDA was found in Solomon Islands and Caucasian women (17 vs. 23%, p=0.478). The frequency of red meat, prepared meat and offal, and all white meat consumption did not differ between the two groups (p=0.187). There was a significant difference in fish/seafood consumption (p=0.001), Solomon Islands women consumed fish/seafood more frequently than Caucasian women. Solomon Islands women also consumed medium-high vitamin C fruits more frequently (p=0.002) and dairy products less frequently (p=0.001) than Caucasian women. No significant difference (p=0.872) was identified in the frequency of intake of beverages containing polyphenol between the two groups. But the analysis of individual beverages showed that Solomon Islands women more frequently consumed black tea compared to Caucasian women, the similar practice was identified from the dietary habit assessment where 40% of Solomon Islands women drank black tea an hour before or after evening meals. Fewer Solomon Islands women consumed multivitamins/minerals than Caucasian women (12.8% vs. 66.7% respectively) and none of the Solomon Islands women reported taking dietary supplements compared to 44% Caucasian women. In regards to menstrual blood loss, although there was no significant difference between the two groups in overall menstrual blood loss units, Caucasian women reported on average 1 day longer menstrual period than Solomon Islands women. A small number of women in each group had previously donated blood, but in every case it had taken place more than 6 months prior to this…
Subjects/Keywords: Solomon Islands women;
Health and hygiene;
Iron status;
Iron in the body;
Iron deficiency anemia
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kafa, R. I. (2012). Iron status and factors influencing iron status of Solomon Islands women living in New Zealand : a thesis presented in the partial fulfillment of the requirements for the degree of Masters of Science (Human Nutrition), Massey University, Albany, New Zealand
. (Thesis). Massey University. Retrieved from http://hdl.handle.net/10179/4718
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Kafa, Rosemary I'ilu. “Iron status and factors influencing iron status of Solomon Islands women living in New Zealand : a thesis presented in the partial fulfillment of the requirements for the degree of Masters of Science (Human Nutrition), Massey University, Albany, New Zealand
.” 2012. Thesis, Massey University. Accessed January 23, 2021.
http://hdl.handle.net/10179/4718.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Kafa, Rosemary I'ilu. “Iron status and factors influencing iron status of Solomon Islands women living in New Zealand : a thesis presented in the partial fulfillment of the requirements for the degree of Masters of Science (Human Nutrition), Massey University, Albany, New Zealand
.” 2012. Web. 23 Jan 2021.
Vancouver:
Kafa RI. Iron status and factors influencing iron status of Solomon Islands women living in New Zealand : a thesis presented in the partial fulfillment of the requirements for the degree of Masters of Science (Human Nutrition), Massey University, Albany, New Zealand
. [Internet] [Thesis]. Massey University; 2012. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/10179/4718.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Kafa RI. Iron status and factors influencing iron status of Solomon Islands women living in New Zealand : a thesis presented in the partial fulfillment of the requirements for the degree of Masters of Science (Human Nutrition), Massey University, Albany, New Zealand
. [Thesis]. Massey University; 2012. Available from: http://hdl.handle.net/10179/4718
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
22.
Granado, Fernanda Serra.
Evolução de indicadores nutricionais de saúde infantil entre 2003 e 2007 em área urbana de Acrelândia, Acre.
Degree: Mestrado, Nutrição em Saúde Pública, 2011, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/6/6138/tde-09092011-102559/
;
► Introdução: O panorama nutricional da infância brasileira nas últimas décadas caracteriza-se por tendência ao declínio da prevalência da desnutrição com manutenção da prevalência de anemia,…
(more)
▼ Introdução: O panorama nutricional da infância brasileira nas últimas décadas caracteriza-se por tendência ao declínio da prevalência da desnutrição com manutenção da prevalência de anemia, principalmente a ferropriva. Contudo, desigualdades regionais ainda persistem especialmente na região norte do país. A substituição precoce e inadequada do aleitamento materno por outros alimentos tem sido considerada principal responsável pelas deficiências nutricionais entre menores de dois anos. Objetivo: Caracterizar a evolução das práticas de aleitamento materno, prevalências de anemia, deficiência de ferro e desnutrição em crianças menores de 2 anos em área urbana de Acrelândia, Estado do Acre. Métodos: Análise temporal de dois inquéritos transversais de base populacional realizados em 2003 (n= 170) e 2007 (n= 224). Informações sobre condições socioeconômicas, morbidade e aleitamento materno foram obtidas por meio de questionário estruturado. Peso e comprimento das crianças foram medidos pela equipe de pesquisa, sendo considerada desnutrida a criança cujo indicador de altura para idade encontrava-se abaixo de 2 escores z, segundo padrão da Organização Mundial da Saúde (OMS). Avaliaram-se as concentrações de hemoglobina sanguínea (maiores de 6 meses de idade), ferritina e receptor de transferrina plasmáticos para diagnóstico de anemia e deficiência de ferro segundo critérios da OMS. Resultados: Na comparação entre os inquéritos 2003 e 2007, não houve diferenças estatisticamente significantes nas prevalências (intervalo com 95 por cento de confiança) de aleitamento materno total de 46 por cento (39 por cento -54 por cento ) para 53 por cento (46 por cento -59 por cento ), aleitamento materno exclusivo em menores de 6 meses de 23 por cento (10 por cento -41 por cento ) para 16 por cento (6 por cento -34 por cento ), desnutrição de 9 por cento (5 por cento -14 por cento ) para 11 por cento (8 por cento -16 por cento ), anemia de 48 por cento (39 por cento -56 por cento ) para 40 por cento (33 por cento -47 por cento ) e anemia ferropriva de 36 por cento (28 por cento -45 por cento ) para 36 por cento (29 por cento -44 por cento ), respectivamente. No entanto, houve aumento na prevalência de deficiência de ferro de 62 por cento (53 por cento -70 por cento ) para 81 por cento (75 por cento -86 por cento ) (teste do c2, p0,001). Conclusão: A presente análise não observou melhorias na prática de aleitamento materno total e exclusivo e na ocorrência de anemia no período analisado, revelando um cenário preocupante para saúde pública com aumento significativo da prevalência de deficiência de ferro nas crianças estudadas
Introduction: The nutritional picture of Brazilian infancy in recent decades is characterized by a downward trend in the prevalence of malnutrition and unchanged prevalence of anemia, especially iron deficiency anemia. However, regional inequalities persist, particularly in the North of the country. The early and inadequate introduction of foods has been considered the main factor responsible for…
Advisors/Committee Members: Cardoso, Marly Augusto.
Subjects/Keywords: Acre; Acre; Aleitamento Materno; Anemia; Anemia; Breastfeeding; Deficiência de Ferro; Desnutrição; Iron Deficiency; Malnutrition
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Granado, F. S. (2011). Evolução de indicadores nutricionais de saúde infantil entre 2003 e 2007 em área urbana de Acrelândia, Acre. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/6/6138/tde-09092011-102559/ ;
Chicago Manual of Style (16th Edition):
Granado, Fernanda Serra. “Evolução de indicadores nutricionais de saúde infantil entre 2003 e 2007 em área urbana de Acrelândia, Acre.” 2011. Masters Thesis, University of São Paulo. Accessed January 23, 2021.
http://www.teses.usp.br/teses/disponiveis/6/6138/tde-09092011-102559/ ;.
MLA Handbook (7th Edition):
Granado, Fernanda Serra. “Evolução de indicadores nutricionais de saúde infantil entre 2003 e 2007 em área urbana de Acrelândia, Acre.” 2011. Web. 23 Jan 2021.
Vancouver:
Granado FS. Evolução de indicadores nutricionais de saúde infantil entre 2003 e 2007 em área urbana de Acrelândia, Acre. [Internet] [Masters thesis]. University of São Paulo; 2011. [cited 2021 Jan 23].
Available from: http://www.teses.usp.br/teses/disponiveis/6/6138/tde-09092011-102559/ ;.
Council of Science Editors:
Granado FS. Evolução de indicadores nutricionais de saúde infantil entre 2003 e 2007 em área urbana de Acrelândia, Acre. [Masters Thesis]. University of São Paulo; 2011. Available from: http://www.teses.usp.br/teses/disponiveis/6/6138/tde-09092011-102559/ ;
23.
Machado, Edna Helena da Silva.
Anemia em gestantes atendidas em Unidades Básicas de Saúde da região administrativa do Butantã, município de São Paulo, em 2006 e 2008.
Degree: PhD, Nutrição Humana Aplicada, 2011, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/89/89131/tde-15072011-103018/
;
► O presente estudo verificou a prevalência de anemia em gestantes atendidas em 13 Unidades Básicas de Saúde da Supervisão Técnica de Saúde do Butantã-SP. Trata-se…
(more)
▼ O presente estudo verificou a prevalência de anemia em gestantes atendidas em 13 Unidades Básicas de Saúde da Supervisão Técnica de Saúde do Butantã-SP. Trata-se de estudo transversal com dados secundários de prontuários de 772 gestantes, à primeira consulta do pré-natal, nos anos de 2006 (387) e de 2008 (385). Foram incluídas no estudo as gestantes cujos prontuários apresentavam os seguintes dados: idade, peso, trimestre gestacional, concentração de hemoglobina e RDW na primeira consulta de pré-natal e ausência de doenças crônicas. De acordo com o estado nutricional pré-gestacional, observaram-se maiores prevalências de eutrofia (61 %), seguidas por 21,5 % de sobrepeso e por 10,8 % de obesidade. A prevalência de anemia foi de 10,0 % em 2006 e de 8,8 % em 2008, sem diferença estatisticamente significativa entre os valores (p > 0,05). Como esperado, a prevalência aumentou com a evolução da gestação. Em 2006 as médias de Hb diminuíram de 12,6 (1,0) g/dL no I trimestre para 12,2 (1,1) g/dL no II trimestre e 11,5 (1,0) g/dL no III trimestre gestacional. Os valores foram similares no ano de 2008. A distribuição das médias de Hb e RDW nos dois anos não mostrou diferenças estatísticas significativas (p > 0,05). As gestantes que estavam no II trimestre apresentaram risco de anisocitose maior em 41%, quando comparadas às que fizeram sua primeira consulta no primeiro trimestre. Esse nível de prevalência de anemia é classificado como associado a um risco populacional leve, segundo a Organização Mundial de Saúde.
The present study verified the prevalence of anemia among pregnant women assisted in 13 Health Basic Units of the Health Technical Supervision in Butantã-SP. This is a cross-sectional study with secondary data from medical charts of 772 pregnant women, upon the first prenatal visit to the doctor, in 2006 (387 women) and 2008 (385 women). The study included pregnant women whose medical charts contained the following data: age, weight, gestational quarter, hemoglobin concentration and RDW upon the first prenatal visit and lack of chronic diseases. According to the gestational nutritional status, the largest prevalence of eutrophic women (61 %) was observed, followed by 21.5 % overweight and 10.8 % obese. The prevalence of anemia was 10.0 % in 2006 and 8.8 % in 2008, with no statistically significant difference between the values (p > 0.05). As expected, the prevalence increased with the evolution of gestation. In 2006, the mean Hb values decreased from 12.6 (1.0) g/dL in the first quarter to 12.2 (1.1) g/dL in the second quarter and 11.5 (1.0) g/dL in the third quarter of pregnancy. The values were similar in 2008. The mean Hb distribution and RDW in both years showed no statistically significant differences (p > 0.05). The pregnant women who were in the second quarter of pregnancy showed a 41 % larger risk of anisocytosis when compared to the ones who attended the first medical visit in the first quarter of pregnancy. This level of prevalence for anemia is classified as associated to a slight risk for the population,…
Advisors/Committee Members: Colli, Celia.
Subjects/Keywords: Anemia; Anemia; Carência de ferro; Gestação; Gestation; Health policy; Iron deficiency; Política de saúde
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Machado, E. H. d. S. (2011). Anemia em gestantes atendidas em Unidades Básicas de Saúde da região administrativa do Butantã, município de São Paulo, em 2006 e 2008. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/89/89131/tde-15072011-103018/ ;
Chicago Manual of Style (16th Edition):
Machado, Edna Helena da Silva. “Anemia em gestantes atendidas em Unidades Básicas de Saúde da região administrativa do Butantã, município de São Paulo, em 2006 e 2008.” 2011. Doctoral Dissertation, University of São Paulo. Accessed January 23, 2021.
http://www.teses.usp.br/teses/disponiveis/89/89131/tde-15072011-103018/ ;.
MLA Handbook (7th Edition):
Machado, Edna Helena da Silva. “Anemia em gestantes atendidas em Unidades Básicas de Saúde da região administrativa do Butantã, município de São Paulo, em 2006 e 2008.” 2011. Web. 23 Jan 2021.
Vancouver:
Machado EHdS. Anemia em gestantes atendidas em Unidades Básicas de Saúde da região administrativa do Butantã, município de São Paulo, em 2006 e 2008. [Internet] [Doctoral dissertation]. University of São Paulo; 2011. [cited 2021 Jan 23].
Available from: http://www.teses.usp.br/teses/disponiveis/89/89131/tde-15072011-103018/ ;.
Council of Science Editors:
Machado EHdS. Anemia em gestantes atendidas em Unidades Básicas de Saúde da região administrativa do Butantã, município de São Paulo, em 2006 e 2008. [Doctoral Dissertation]. University of São Paulo; 2011. Available from: http://www.teses.usp.br/teses/disponiveis/89/89131/tde-15072011-103018/ ;
Universidade Federal do Maranhão
24.
ISABELLA AZEVEDO GOMES.
Deficiência de ferro como indicador de risco para cárie de estabelecimento precoce severa em crianças de 24 a 36 meses.
Degree: 2009, Universidade Federal do Maranhão
URL: http://www.tedebc.ufma.br//tde_busca/arquivo.php?codArquivo=399
► O objetivo foi avaliar a associação entre deficiência de ferro e cárie de estabelecimento precoce severa em crianças de 24 a 36 meses; levantando-se indicadores…
(more)
▼ O objetivo foi avaliar a associação entre deficiência de ferro e cárie de estabelecimento precoce severa em crianças de 24 a 36 meses; levantando-se indicadores de riscos hematológicos que possam estar relacionados ao estabelecimento precoce da doença. No exame clínico intra-bucal foram avaliados os índices de cárie (ceo), preconizado pela OMS, e presença de manchas brancas ativas (MBA).Todas as crianças foram submetidas a uma coleta de sangue , sendo as amostras mantidas refrigeradas e enviadas para processamento no Laboratório de Análises do Hemomar (São Luís-MA), para avaliação dos níveis de hemoglobina, ferritina e ferro sérico.As informações obtidas foram consolidadas em bancos de dados do programa STATA 9.0.Foi aplicada uma regressão de Poisson para associação entre as variáveis dependentes (ceo e MBA) e demais variáveis, sendo a razão das prevalências (IR) e intervalo de confiança (IC 95%).Foi observado que quanto maior o número de cavidades de cárie nas crianças, menores foram os níveis séricos da hemoglobina. Em se tratando da atividade da doença cárie (MBA), foi encontrado que quanto maior o número de lesões iniciais, menores foram os níveis séricos de hemoglobina, ferritina e ferro sérico. Os dados mostram que os níveis séricos das variáveis marcadoras da anemia ferropriva são menores quanto maior o número de lesões cariosas em crianças com cárie precoce severa.
The aim was evaluate the association between iron deficiency and severe early childhood caries in children between 24 and 36 months; rising hematological indicators that can be related to early establishment of the disease. At intraoral exam the caries index (def) praised by WHO, and the presence of active white spots (AWP) were evaluated. All the children were submitted to a bloody collection, being the samples frozen and sent to processing at Hemomar Analysis Laboratory (São Luís, Maranhão, Brazil), for the evaluation of hemoglobin, ferritin and serumal iron levels. The obtained information was consolidated in data bank of STATA 9.0 program. The Poisson regression model was applied to the association between dependent variables (def and AWP) and others, being the prevalence ratio and confidence interval (IC 95%). It was certified that the higher the number of caries cavities in children, the lower are the hemoglobin levels in serum. About caries activity (AWP), it was observed that the higher the number of initial lesions, the lower is the levels in serum of hemoglobin, ferritin and serumal iron. The data show that the levels in serum of the marked variables of iron deficiency anemia are lower when the number of caries lesions in children with severe early childhood caries is higher.
Advisors/Committee Members: Cecília Cláudia Costa Ribeiro.
Subjects/Keywords: Cárie; Nutritional state; Estado nutricional; SAUDE MATERNO-INFANTIL; Iron deficiency anemia; Anemia ferropriva; Caries
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
GOMES, I. A. (2009). Deficiência de ferro como indicador de risco para cárie de estabelecimento precoce severa em crianças de 24 a 36 meses. (Thesis). Universidade Federal do Maranhão. Retrieved from http://www.tedebc.ufma.br//tde_busca/arquivo.php?codArquivo=399
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
GOMES, ISABELLA AZEVEDO. “Deficiência de ferro como indicador de risco para cárie de estabelecimento precoce severa em crianças de 24 a 36 meses.” 2009. Thesis, Universidade Federal do Maranhão. Accessed January 23, 2021.
http://www.tedebc.ufma.br//tde_busca/arquivo.php?codArquivo=399.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
GOMES, ISABELLA AZEVEDO. “Deficiência de ferro como indicador de risco para cárie de estabelecimento precoce severa em crianças de 24 a 36 meses.” 2009. Web. 23 Jan 2021.
Vancouver:
GOMES IA. Deficiência de ferro como indicador de risco para cárie de estabelecimento precoce severa em crianças de 24 a 36 meses. [Internet] [Thesis]. Universidade Federal do Maranhão; 2009. [cited 2021 Jan 23].
Available from: http://www.tedebc.ufma.br//tde_busca/arquivo.php?codArquivo=399.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
GOMES IA. Deficiência de ferro como indicador de risco para cárie de estabelecimento precoce severa em crianças de 24 a 36 meses. [Thesis]. Universidade Federal do Maranhão; 2009. Available from: http://www.tedebc.ufma.br//tde_busca/arquivo.php?codArquivo=399
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Brigham Young University
25.
Chamberlain, Angela.
Examining the Relationship Between Anemia, Cognitive Function, and Socioeconomic Status in School-Aged Ecuadorian Children.
Degree: MS, 2015, Brigham Young University
URL: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=6916&context=etd
► Background and Objectives: It is estimated that over 40% of children in Ecuador are anemic. Anemia in children can influence physical and cognitive development…
(more)
▼ Background and Objectives: It is estimated that over 40% of children in Ecuador are anemic. Anemia in children can influence physical and cognitive development and have lasting effects on adulthood productivity and quality of life. The objectives of this study were to: (1) evaluate the relationship of anemia and cognitive function, and (2) determine the influence of demographic factors on cognitive function. Population and Setting: The sample consisted of 175 school-aged children between 5 to 11 years old attending a school in a poverty stricken area of Guayaquil, Ecuador. Methods: A descriptive correlational cross sectional design was used to study the relationship between the level of anemia and the level of cognitive function. Other demographic factors were evaluated to determine their influence on cognitive function. Data were collected at the school using the Raven's Coloured Progressive Matrices to measure cognitive function and the STAT-Site MHgb Meter to measure hemoglobin levels. Results: No significant correlation was found between the level of anemia and cognitive function. Multiple regression analysis of demographic variables and cognitive function found age (Beta=0.56, t=8.6, p=0.000) and income (Beta=0.16, t=2.5, p=0.01) to be significant predictors of cognitive function. Interpretation and Conclusion: Many factors influence cognitive function and development. Additional research is needed to determine the effect of income level and related factors, such as parental time spent with the child doing homework, value placed on education in the home, education level of the parents, and quality of nutrition. Interventions to improve socioeconomic level, enhance parenting styles that foster cognitive development, and improve nutrition should be implemented.
Subjects/Keywords: anemia; iron deficiency anemia; cognitive function; cognitive development; socioeconomic status; income; Nursing
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Chamberlain, A. (2015). Examining the Relationship Between Anemia, Cognitive Function, and Socioeconomic Status in School-Aged Ecuadorian Children. (Masters Thesis). Brigham Young University. Retrieved from https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=6916&context=etd
Chicago Manual of Style (16th Edition):
Chamberlain, Angela. “Examining the Relationship Between Anemia, Cognitive Function, and Socioeconomic Status in School-Aged Ecuadorian Children.” 2015. Masters Thesis, Brigham Young University. Accessed January 23, 2021.
https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=6916&context=etd.
MLA Handbook (7th Edition):
Chamberlain, Angela. “Examining the Relationship Between Anemia, Cognitive Function, and Socioeconomic Status in School-Aged Ecuadorian Children.” 2015. Web. 23 Jan 2021.
Vancouver:
Chamberlain A. Examining the Relationship Between Anemia, Cognitive Function, and Socioeconomic Status in School-Aged Ecuadorian Children. [Internet] [Masters thesis]. Brigham Young University; 2015. [cited 2021 Jan 23].
Available from: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=6916&context=etd.
Council of Science Editors:
Chamberlain A. Examining the Relationship Between Anemia, Cognitive Function, and Socioeconomic Status in School-Aged Ecuadorian Children. [Masters Thesis]. Brigham Young University; 2015. Available from: https://scholarsarchive.byu.edu/cgi/viewcontent.cgi?article=6916&context=etd
Universidade Federal de Santa Maria
26.
Iria Luiza Gomes Farias.
COMPRIMIDOS MASTIGÁVEIS DE FERRO CARBONILA PARA TRATAMENTO DA ANEMIA FERROPRIVA DE CRIANÇAS MENORES DE SEIS ANOS.
Degree: 2006, Universidade Federal de Santa Maria
URL: http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=697
► The objective this study is verify the efficiency and occurrence of collateral effects with the use of carbonyl iron powder, in the form of chewable…
(more)
▼ The objective this study is verify the efficiency and occurrence of collateral effects with the use of carbonyl iron powder, in the form of chewable tablets, in order to enable the use of an alternative to the conventional treatment of iron deficiency anemia with ferrous sulfate, for children under 6 years of age. The intervention proposed for the treatment of iron deficiency anemia in children almost always consists of ferrous sulfate drops that do not have the desired effectiveness. Several studies have proven the low adherence to the treatment due to collateral effects of the medication (gastrointestinal intolerance, alterations in color and consistency of stools, impregnation of iron in diapers and teeth), to the prolonged daily administration in the form of drops, to the metallic taste, as well as to socio-cultural aspects. In choosing the preparation, the content of the iron ion, tolerance, absorption, effectiveness and cost must all be considered. Carbonyl iron powder is obtained by decomposition of Fe pentacarbonyl at high temperatures, resulting in extremely pure elemental Fe (Fe0), in the form of non-toxic micro-spheres of 4-7/μm, with bioavailability in relation to 58-70% ferrous sulfate and it does not confer a metallic taste to the preparation. An open randomized clinical assay was carried out. The group studied (CA) received Carbonyl Iron and the control group (SF) received a solution of Ferrous Sulfate, both at a dose of 5mg/Kg/day, for 90 days. Seventy-three children from Family Health Units (FHU) of Santa Maria, Brazil, participated in the study. Blood was collected at 0, 30 and 90 days of treatment. The hemograms were carried out in STKS (Coulter, USA), serum iron and TIBC, by colorimetric assay and ferritin by immunometric assay. The data was analyzed with the EpiInfo program, version 3.3.2, from CDC/USA. The increase in Hb after 30 days of treatment was of 1.3g/dl (SD 0.92) for group CA and of 1.2g/dl (SD 1.13) for group SF (p>0.05). After 90 days of treatment, CA had favorable results for Ht, MCV, MCH, TIBC and ferritin (p<0.05). None of the children from group CA presented side effects, in group SF, 62% of the children presented diarrhea and/or experienced vomiting. The number of children from the control group who continued to present a level of Hb lower than 11g/dl was two-fold that of the group that received carbonyl iron. Based on the results demonstrating the same effectiveness at 30 days as for the standard ferrous sulfate and the superior results at 90 days of treatment, together with the safety (low toxicity) and excellent acceptance, carbonyl iron should be considered an important option for the therapeutic treatment of iron deficiency anemia in children under the age of six.
O objetivo deste estudo é verificar a eficácia, ocorrência de efeitos colaterais e aceitação de ferro carbonila em pó, na forma de comprimidos mastigáveis, para possibilitar uma alternativa ao tratamento convencional da anemia ferropriva com sulfato ferroso, para crianças menores de seis anos. A intervenção…
Advisors/Committee Members: Sergio Luiz Dalmora, Jose Edson Paz da Silva, Angela Regina Maciel Weinmann.
Subjects/Keywords: ferro carbonila em pó; ferro elementar em pó; anemia ferropriva; FARMACIA; carbonyl iron powder; elemental iron powder; iron deficiency anemia
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Farias, I. L. G. (2006). COMPRIMIDOS MASTIGÁVEIS DE FERRO CARBONILA PARA TRATAMENTO DA ANEMIA FERROPRIVA DE CRIANÇAS MENORES DE SEIS ANOS. (Thesis). Universidade Federal de Santa Maria. Retrieved from http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=697
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Farias, Iria Luiza Gomes. “COMPRIMIDOS MASTIGÁVEIS DE FERRO CARBONILA PARA TRATAMENTO DA ANEMIA FERROPRIVA DE CRIANÇAS MENORES DE SEIS ANOS.” 2006. Thesis, Universidade Federal de Santa Maria. Accessed January 23, 2021.
http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=697.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Farias, Iria Luiza Gomes. “COMPRIMIDOS MASTIGÁVEIS DE FERRO CARBONILA PARA TRATAMENTO DA ANEMIA FERROPRIVA DE CRIANÇAS MENORES DE SEIS ANOS.” 2006. Web. 23 Jan 2021.
Vancouver:
Farias ILG. COMPRIMIDOS MASTIGÁVEIS DE FERRO CARBONILA PARA TRATAMENTO DA ANEMIA FERROPRIVA DE CRIANÇAS MENORES DE SEIS ANOS. [Internet] [Thesis]. Universidade Federal de Santa Maria; 2006. [cited 2021 Jan 23].
Available from: http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=697.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Farias ILG. COMPRIMIDOS MASTIGÁVEIS DE FERRO CARBONILA PARA TRATAMENTO DA ANEMIA FERROPRIVA DE CRIANÇAS MENORES DE SEIS ANOS. [Thesis]. Universidade Federal de Santa Maria; 2006. Available from: http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=697
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
27.
Ohno, Yukako.
Liver Congestion in Heart Failure Contributes to Inappropriately Increased Serum Hepcidin despite Anemia : 心不全に伴う肝うっ血は貧血に関わらずヘプシジンの不適切分泌の一因となる.
Degree: 博士（医学）, 2015, Niigata University / 新潟大学
URL: http://hdl.handle.net/10191/32271
► 学位の種類: 博士（医学）. 報告番号: 甲第3987号. 学位記番号: 新大院博（医）甲第633号. 学位授与年月日: 平成27年3月23日
The Tohoku Journal of Experimental Medicine. 2015, 235(1), 69-79.
Hepcidin is a key regulator of mammalian iron…
(more)
▼ 学位の種類: 博士（医学）. 報告番号: 甲第3987号. 学位記番号: 新大院博（医）甲第633号. 学位授与年月日: 平成27年3月23日
The Tohoku Journal of Experimental Medicine. 2015, 235(1), 69-79.
Hepcidin is a key regulator of mammalian iron metabolism and mainly produced by the liver. Hepcidin excess causes iron deficiency and anemia by inhibiting iron absorption from the intestine and iron release from macrophage stores. Anemia is frequently complicated with heart failure. In heart failure patients, the most frequent histologic appearance of liver is congestion. However, it remains unclear whether liver congestion associated with heart failure influences hepcidin production, thereby contributing to anemia and functional iron deficiency. In this study, we investigated this relationship in clinical and basic studies. In clinical studies of consecutive heart failure patients (n =320), anemia was a common comorbidity (41%). In heart failure patients without active infection and ongoing cancer (n = 30), log-serum hepcidin concentration of patients with liver congestion was higher than those without liver congestion (p = 0.0316). Moreover, in heart failure patients with liver congestion (n = 19), the anemia was associated with the higher serum hepcidin concentrations, which is a type of anemia characterized by induction of hepcidin. Subsequently, we produced a rat model of heart failure with liver congestion by injecting monocrotaline that causes pulmonary hypertension. The monocrotaline-treated rats displayed liver congestion with increase of hepcidin expression at 4 weeks after monocrotaline injection, followed by anemia and functional iron deficiency observed at 5 weeks. We conclude that liver congestion induces hepcidin production, which may result in anemia and functional iron deficiency in some patients with heart failure.
Subjects/Keywords: anemia; heart failure; hepcidin; iron deficiency; liver congestion
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ohno, Y. (2015). Liver Congestion in Heart Failure Contributes to Inappropriately Increased Serum Hepcidin despite Anemia : 心不全に伴う肝うっ血は貧血に関わらずヘプシジンの不適切分泌の一因となる. (Thesis). Niigata University / 新潟大学. Retrieved from http://hdl.handle.net/10191/32271
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Ohno, Yukako. “Liver Congestion in Heart Failure Contributes to Inappropriately Increased Serum Hepcidin despite Anemia : 心不全に伴う肝うっ血は貧血に関わらずヘプシジンの不適切分泌の一因となる.” 2015. Thesis, Niigata University / 新潟大学. Accessed January 23, 2021.
http://hdl.handle.net/10191/32271.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Ohno, Yukako. “Liver Congestion in Heart Failure Contributes to Inappropriately Increased Serum Hepcidin despite Anemia : 心不全に伴う肝うっ血は貧血に関わらずヘプシジンの不適切分泌の一因となる.” 2015. Web. 23 Jan 2021.
Vancouver:
Ohno Y. Liver Congestion in Heart Failure Contributes to Inappropriately Increased Serum Hepcidin despite Anemia : 心不全に伴う肝うっ血は貧血に関わらずヘプシジンの不適切分泌の一因となる. [Internet] [Thesis]. Niigata University / 新潟大学; 2015. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/10191/32271.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Ohno Y. Liver Congestion in Heart Failure Contributes to Inappropriately Increased Serum Hepcidin despite Anemia : 心不全に伴う肝うっ血は貧血に関わらずヘプシジンの不適切分泌の一因となる. [Thesis]. Niigata University / 新潟大学; 2015. Available from: http://hdl.handle.net/10191/32271
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
28.
Carmo, Lilian Sheila de Melo Pereira do.
O uso de suplemento a base de ferro e os níveis de hemoglobina identificados durante o período gravídico-puerperal.
Degree: Mestrado, Enfermagem em Saúde Pública, 2007, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/22/22133/tde-18122007-153621/
;
► O uso de suplemento a base de ferro é fundamental para profilaxia e tratamento da anemia ferropriva, agravo freqüente em gestantes que vivem em paises…
(more)
▼ O uso de suplemento a base de ferro é fundamental para profilaxia e tratamento da anemia ferropriva, agravo freqüente em gestantes que vivem em paises em desenvolvimento, e que se não for tratada, pode ter conseqüências tanto para mulher quanto para o feto. Entretanto, muitas mulheres não aderem a terapêutica. O objetivo deste estudo foi identificar a utilização de suplemento à base de ferro no ciclo grávido-puerperal, em um grupo de mulheres.Trata-se de um estudo descritivo com abordagem quantiqualitativa realizado em uma Unidade Básica e Distrital de Saúde (UBDS) de Ribeirão Preto, e que teve como sujeitos um grupo de mulheres, usuárias de um serviço de saúde, que compareceram a UBDS para consulta de puericultura. A coleta foi realizada através de entrevista, coleta de sangue para dosagem de hemoglobina e consulta aos prontuários. A idade das mulheres variou entre 19 a 24 anos, sendo que destas 36,3% apresentaram ensino fundamental incompleto e 75% referiu não trabalhar. Quanto a realização de pré-natal, 75% realizou em Centro ou Posto de Saúde tendo como média de consultas durante a gestação oito. Durante a gestação e o puerpério o valor médio de hemoglobina encontrado nas entrevistadas foi de 12,1 g/dl e 12 g/dl, respectivamente. Quanto ao uso de suplemento a base de ferro na gestação e puerpério, 81,8% referiu ter usado durante a gestação e 66,9% no puerpério. Assim, conseguimos identificar que a maioria das gestantes fez uso do suplemento durante a gestação e puerpério e que apresentaram hemoglobina maior que 11 g/dl, ou seja, não apresentavam anemia. Os dados qualitativos revelam que as mulheres desconhecem a importância do uso do suplemento neste período, sendo mais evidente a preocupação com a saúde do feto.
The supplement use the iron base is basic for Prophylaxis and treatment of the ferropriva anemia, I aggravate frequent in gestantes that live in paises in development, and that if it will not be treated, it can in such a way have consequences for woman how much for the embryo. However, many women do not adhere the therapeutical one. The objective of this study was to identify the use of supplement to the base of iron in the pregnant-puerperal cycle, in a group of mulheres.Trata-if of a descriptive study with carried through quantiqualitativa boarding in a Basic and District Unit of Saúde (UBDS) of Ribeirão Preto, and that a group of women had as citizens, users of a health service, who had appeared the UBDS for puericultura consultation. The collection was carried through through interview, collection of blood for dosage of hemoglobina and consults to handbooks. The age of the women varied enters the 19 24 years, being that of these 36.3% had presented incomplete basic education and 75% related not to work. How much the accomplishment of prenatal, 75% carried through in Center or Rank of Health having as average of consultations during gestation eight. During the gestation and the puerpério the average value of hemoglobina found in the interviewed ones was of 12,1 g/dl and 12 g/dl, respectively. How…
Advisors/Committee Members: Gomes, Flávia Azevedo.
Subjects/Keywords: anaemia; anemia; deficiência de ferro; gestação; iron deficiency; pregnancy
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Carmo, L. S. d. M. P. d. (2007). O uso de suplemento a base de ferro e os níveis de hemoglobina identificados durante o período gravídico-puerperal. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/22/22133/tde-18122007-153621/ ;
Chicago Manual of Style (16th Edition):
Carmo, Lilian Sheila de Melo Pereira do. “O uso de suplemento a base de ferro e os níveis de hemoglobina identificados durante o período gravídico-puerperal.” 2007. Masters Thesis, University of São Paulo. Accessed January 23, 2021.
http://www.teses.usp.br/teses/disponiveis/22/22133/tde-18122007-153621/ ;.
MLA Handbook (7th Edition):
Carmo, Lilian Sheila de Melo Pereira do. “O uso de suplemento a base de ferro e os níveis de hemoglobina identificados durante o período gravídico-puerperal.” 2007. Web. 23 Jan 2021.
Vancouver:
Carmo LSdMPd. O uso de suplemento a base de ferro e os níveis de hemoglobina identificados durante o período gravídico-puerperal. [Internet] [Masters thesis]. University of São Paulo; 2007. [cited 2021 Jan 23].
Available from: http://www.teses.usp.br/teses/disponiveis/22/22133/tde-18122007-153621/ ;.
Council of Science Editors:
Carmo LSdMPd. O uso de suplemento a base de ferro e os níveis de hemoglobina identificados durante o período gravídico-puerperal. [Masters Thesis]. University of São Paulo; 2007. Available from: http://www.teses.usp.br/teses/disponiveis/22/22133/tde-18122007-153621/ ;
29.
Almashjary, Majed.
The Impact of Dietary Iron Restriction on Sickling Kinetics and Hemolysis in A Transgenic Model of Sickle Cell Disease.
Degree: 2020, The Catholic University of America
URL: http://hdl.handle.net/1961/cuislandora:214730
► Sickle cell disease (SCD) is caused by polymerization of deoxy-hemoglobin-S (HbS) within the red blood cell (RBC). HbS polymerization is a concentration-dependent process. I hypothesized…
(more)
▼ Sickle cell disease (SCD) is caused by polymerization of deoxy-hemoglobin-S (HbS) within the red blood cell (RBC). HbS polymerization is a concentration-dependent process. I hypothesized that dietary
iron restriction would decrease the concentration of HbS in the RBC, resulting in delayed sickling, and decreased organ injury.To test this hypothesis, I studied male and female transgenic mice that express the human gamma, alpha and beta globin-S genes (SCD mice). To induce
iron deficiency, mice were fed an
iron-restricted diet (0-3 ppm
iron) introduced at weaning. For comparison, parallel cohorts were fed an
iron-sufficient diet (39 ppm
iron) or an
iron-abundant diet (821 ppm
iron) also introduced at weaning. After 2, 4, or 6 months on the diets, mice were euthanized to collect blood and harvest tissues.
Iron availability was determined by measuring plasma ferritin and hepcidin using ELISA kits. RBC and reticulocyte parameters were measured by an automated hematology analyzer. Hemoglobin composition was quantified by ion-exchange chromatography. Hb-O2 affinity was measured by sickling assay and HEMOX-Analyzer. RBC sickling was measured as the half-life of cells remaining round after exposure to 3% oxygen. Hemolysis was evaluated by measuring the absorbance of plasma heme, and the concentration of the heme and hemoglobin scavengers hemopexin and haptoglobin by ELISA. To examine tissues, animals were first perfused PBS. Organs were weighed to determine organ/body mass indices. Liver, spleen, and kidneys were preserved in formalin and embedded in paraffin for sectioning. Sections were stained with Prussian blue to determine
iron deposition and stained with hematoxylin and eosin for histologic analysis by a veterinary pathologist. Histologic evidence of hepatic necrosis was reported as either present or absent.Dietary
iron restriction caused depletion of
iron stores as evidenced by lower plasma ferritin levels and suppression of the negative
iron regulator hepcidin in both male and female SCD mice. RBC and reticulocyte parameters were unaffected by dietary
iron restriction, though sex differences and age-related changes were observed. Fetal hemoglobin (HbF) levels were less than 1% and were unchanged by dietary
iron restriction, though HbF levels were higher in females over time. Dietary
iron restriction increased hemoglobin oxygen affinity in the first cohort, but this finding was not confirmed in a second cohort. The half-life of round cells under conditions of 3% oxygen was increased in SCD mice after 4 or 6 months of dietary
iron restriction, but not after 2 months. The plasma heme concentration was decreased by the dietary
iron-restriction at 4 and 6 months in the first cohort but was unchanged in the second cohort. Liver mass indices were decreased in mice fed the
iron-restricted diet, and dietary
iron restriction reduced the incidence of hepatic necrosis in the females by half.Dietary
iron restriction was effective at depleting
iron stores and suppressing the negative regulator of
iron uptake, hepcidin.…
Advisors/Committee Members: The Catholic University of America (Degree granting institution), AlSalmi, Wadad (Thesis advisor), Ackerman, Hans (Thesis advisor), Castro, Oswaldo (Committee member), Nestorovich, Ekaterina (Committee member).
Subjects/Keywords: Hematology; Iron Deficiency Anemia; Red Blood Cell; Sickle Cell Disease
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Almashjary, M. (2020). The Impact of Dietary Iron Restriction on Sickling Kinetics and Hemolysis in A Transgenic Model of Sickle Cell Disease. (Thesis). The Catholic University of America. Retrieved from http://hdl.handle.net/1961/cuislandora:214730
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Almashjary, Majed. “The Impact of Dietary Iron Restriction on Sickling Kinetics and Hemolysis in A Transgenic Model of Sickle Cell Disease.” 2020. Thesis, The Catholic University of America. Accessed January 23, 2021.
http://hdl.handle.net/1961/cuislandora:214730.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Almashjary, Majed. “The Impact of Dietary Iron Restriction on Sickling Kinetics and Hemolysis in A Transgenic Model of Sickle Cell Disease.” 2020. Web. 23 Jan 2021.
Vancouver:
Almashjary M. The Impact of Dietary Iron Restriction on Sickling Kinetics and Hemolysis in A Transgenic Model of Sickle Cell Disease. [Internet] [Thesis]. The Catholic University of America; 2020. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/1961/cuislandora:214730.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Almashjary M. The Impact of Dietary Iron Restriction on Sickling Kinetics and Hemolysis in A Transgenic Model of Sickle Cell Disease. [Thesis]. The Catholic University of America; 2020. Available from: http://hdl.handle.net/1961/cuislandora:214730
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Debrecen
30.
Sunna, Lana.
Iron Deficiency Anemia among Women in the Hashemite Kingdom of Jordan
.
Degree: DE – Népegészségügyi Kar, University of Debrecen
URL: http://hdl.handle.net/2437/262835
► This study is aimed to estimate the prevalence of iron deficiency anemia in women age 15 to 49 years in the Hashemite Kingdom of Jordan…
(more)
▼ This study is aimed to estimate the prevalence of
iron deficiency anemia in women age 15 to 49 years in the Hashemite Kingdom of Jordan and analyze the correlation of different variables in relation to the level of
anemia. This study used data that were collected by the Jordan Population and Health Survey (JPFHS) in 2012.
Advisors/Committee Members: Bárdos, Helga (advisor), Debreceni Egyetem::Népegészségügyi Kar::Megelőző Orvostani Intézet (advisor).
Subjects/Keywords: Iron Deficiency;
Anemia;
Jordan
Record Details
Similar Records
Cite
Share »
Record Details
Similar Records
Cite
« Share
❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Sunna, L. (n.d.). Iron Deficiency Anemia among Women in the Hashemite Kingdom of Jordan
. (Thesis). University of Debrecen. Retrieved from http://hdl.handle.net/2437/262835
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Sunna, Lana. “Iron Deficiency Anemia among Women in the Hashemite Kingdom of Jordan
.” Thesis, University of Debrecen. Accessed January 23, 2021.
http://hdl.handle.net/2437/262835.
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Sunna, Lana. “Iron Deficiency Anemia among Women in the Hashemite Kingdom of Jordan
.” Web. 23 Jan 2021.
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Vancouver:
Sunna L. Iron Deficiency Anemia among Women in the Hashemite Kingdom of Jordan
. [Internet] [Thesis]. University of Debrecen; [cited 2021 Jan 23].
Available from: http://hdl.handle.net/2437/262835.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.
Council of Science Editors:
Sunna L. Iron Deficiency Anemia among Women in the Hashemite Kingdom of Jordan
. [Thesis]. University of Debrecen; Available from: http://hdl.handle.net/2437/262835
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.
◁ [1] [2] [3] [4] [5] ▶
. 
Open Access Theses and Dissertations