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You searched for subject:(Hypothalamic amenorrhea). Showing records 1 – 2 of 2 total matches.

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1. Koutoulakis, Ioannis. Μελέτη υποθαλαμικής αμηνόρροιας.

Degree: 2017, University of Ioannina; Πανεπιστήμιο Ιωαννίνων

Hypothalamic amenorrhea, is characterized by the absence of menstrual cycles for three months, low estrogen levels and low/normal levels of gonadotrophins, Functional Hypothalamic Amenorrhea is a commonest cause of primary and secondary amenorrhea, it accounts for over thirty percent of cases of amenorrhea in women of reproductive age and may lead infertility and bone loss. Functional Hypothalamic Amenorrhea occurs when a relative energy deficit (owing eating disorders, excessive exercise) disrupt the secretion of hypothalamic Gonadotrophins Releasing Hormone (GnRH). There are three main types of FHA, all of which are commonly interrelated: stress related amenorrhea, weight loss related amenorrhea and excessive exercise related amenorrhea. There are three main types of FHA, all of which are commonly interrelated: stress related amenorrhea, weight loss related amenorrhea and excessive related amenorrhea. The association between low levels of estrogens (disease such as Premature Ovarian Failure) and cardiovascular disease has been suggested in several studies, but hasn’t been investigated in cases of FHA. Cardiovascular disease, including coronary artery disease, stroke and peripheral vascular disease is the leading cause of death among women. Vascular endothelial dysfunction is an early marker of arteriosclerosis. Women with FHA present and increased risk for cardiovascular disease, which might be attributed to the early onset of vascular endothelial dysfunction associated with sex steroid deficiency. This thesis will constitute a prospective study of patient with FHA who admitted at the Unit of Gynaecological Endocrinology, at the University Hospital of Ioannina, under the main purpose to evaluation of endothelium function by assessment of the Flow Mediated Dilation of brancial artery and correlate to controls group. The secondary objective of this study is to determine the levels of hormones and lipid acids in women with hypothamic amenorrhea and controls group. Also, in this study, the efficacy (through the menstrual period recovery and gonadotrophines levels improvement) of the treatment (including hormone replacement treatment along with weight gain, either reduction in physical exercise or psychotherapy), was observed.

Η υποθαλαμική αμηνόρροια είναι η διακοπή της εμμηνορρυσίας για χρονικό διάστημα μεγαλύτερο των τριών μηνών και χαρακτηρίζεται από χαμηλά επίπεδα των γοναδοτροφινών και των οιστρογόνων λόγω της διαταραχής στην κατά ώσεις έκκριση της GnRH. Η υποθαλαμική αμηνόρροια αποτελεί την συχνότερη αιτία πρωτοπαθούς και δευτεροπαθούς αμηνόρροιας και ευθύνεται για το 30% των γυναικών με αμηνόρροια στην αναπαραγωγική ηλικία. Τα συχνότερα αίτια της υποθαλαμικής αμηνόρροιας είναι η διαταραχή πρόσληψης τροφής (νευρογενής ανορεξία), η έντονη σωματική άσκηση και το στρες. Κύριο χαρακτηριστικό της λειτουργικής υποθαλαμικής αμηνόρροιας αποτελεί η αθλητική τριάδα που περιλαμβάνει τις διαταραχές πρόσληψης ενέργειας, την διαταραχή της εμμήνου ρύσεως και τη διαταραχή του οστικού μεταβολισμού. Η καρδιαγγειακή νόσος όπως η…

Subjects/Keywords: Υποθαλαμική αμηνόρροια; Αμηνόρροια; Ανορεξία; Καρδιαγγειακός κίνδυνος; Hypothalamic amenorrhea; Anorexia; Risk for cardiovascular

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Koutoulakis, I. (2017). Μελέτη υποθαλαμικής αμηνόρροιας. (Thesis). University of Ioannina; Πανεπιστήμιο Ιωαννίνων. Retrieved from http://hdl.handle.net/10442/hedi/44417

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Koutoulakis, Ioannis. “Μελέτη υποθαλαμικής αμηνόρροιας.” 2017. Thesis, University of Ioannina; Πανεπιστήμιο Ιωαννίνων. Accessed August 04, 2020. http://hdl.handle.net/10442/hedi/44417.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Koutoulakis, Ioannis. “Μελέτη υποθαλαμικής αμηνόρροιας.” 2017. Web. 04 Aug 2020.

Vancouver:

Koutoulakis I. Μελέτη υποθαλαμικής αμηνόρροιας. [Internet] [Thesis]. University of Ioannina; Πανεπιστήμιο Ιωαννίνων; 2017. [cited 2020 Aug 04]. Available from: http://hdl.handle.net/10442/hedi/44417.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Koutoulakis I. Μελέτη υποθαλαμικής αμηνόρροιας. [Thesis]. University of Ioannina; Πανεπιστήμιο Ιωαννίνων; 2017. Available from: http://hdl.handle.net/10442/hedi/44417

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

2. O'Donnell, Emma. Cardiovascular Consequences of Estrogen Deficiency: Studies in Premenopausal Women.

Degree: 2013, University of Toronto

The influence of estrogen deficiency in physically active women with functional hypothalamic amenorrhea (ExFHA) on cardiovascular regulation is unknown. Three mechanistic studies compared cardiovascular responses to exercise and orthostatic stress in ExFHA women with responses in physically active (ExOv) and sedentary (SedOv) eumenorrheic ovulatory women. Measures included calf blood flow (BF), brachial artery (BA) endothelial dependent and independent function, shear rate (SR), vascular resistance (VR), blood pressure (BP), heart rate (HR), HR variability (HRV), muscle sympathetic nervous activity (MSNA), and serum renin-angiotensin-aldosterone system (RAAS) components. Study one examined the effects of a single bout of dynamic exercise on vascular function in ExFHA (n=12), ExOv (n=14), and SedOv (n=15) women. Pre-exercise, calf BF and BA endothelium-dependent flow-mediated vasodilation (FMD%) were lower (p<0.05) in ExFHA versus ovulatory women in association with higher (p<0.05) calf VR and lower (p<0.05) SR, respectively. Endothelium-independent vasodilation, assessed at baseline only, was also lower (p<0.05) in ExFHA. Post-exercise, calf BF was increased and VR decreased (p<0.05) in ExFHA women, similar (p>0.05) to that observed in ovulatory women. FMD% and SR were augmented (p<0.05) post-exercise, but both remained lower (p<0.05) in ExFHA versus ovulatory women (p<0.05). Study two investigated neurohumoral (MSNA and RAAS) BP regulation during orthostatic stress in ExFHA (n=12) and ExOv (n=17) women. Baseline systolic BP was lower (p<0.05) in ExFHA versus ExOv. Neurohumoral measures did not differ (p>0.05) between the groups at baseline. However, during hypotensive stimuli, MSNA increased to a greater extent (p<0.05), yet angiotensin II and renin were not activated in ExFHA women. Study three examined autonomic control of HR during orthostatic stress in ExFHA (n=11), ExOv (n=17), and SedOv (n=17) women. Lower HR (p<0.05) at rest and during orthostatic stress in ExFHA was associated with markedly elevated (p<0.05) HRV due to higher (p<0.05) parasympathetic modulation. Sympathetic modulation did not differ (p>0.05) between the groups. These studies indicate altered cardiovascular regulation in otherwise healthy ExFHA women. The influence of estrogen deficiency per se in these alterations are not clear, but in light of the etiology of amenorrhea, it is likely that complex interactions between estrogen and energy deficiency and exercise training are involved.

PhD

Advisors/Committee Members: Goodman, Jack, Harvey, Paula J., Exercise Sciences.

Subjects/Keywords: Cardiovascular; Estrogen; Exercise; Functional Hypothalamic Amenorrhea; 0566

Hypothalamic Amenorrhea.................................................................. 64 2.13… …Cardiovascular Related Findings in Physically Active Women with Functional Hypothalamic Amenorrhea… …FUNCTIONAL HYPOTHALAMIC AMENORRHEA… …women with functional hypothalamic amenorrhea ExOv Physically active women with eumenorrheic… …Functional hypothalamic amenorrhea FMD Flow mediated dilation FMD% Percentage increase in… 

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

O'Donnell, E. (2013). Cardiovascular Consequences of Estrogen Deficiency: Studies in Premenopausal Women. (Doctoral Dissertation). University of Toronto. Retrieved from http://hdl.handle.net/1807/43692

Chicago Manual of Style (16th Edition):

O'Donnell, Emma. “Cardiovascular Consequences of Estrogen Deficiency: Studies in Premenopausal Women.” 2013. Doctoral Dissertation, University of Toronto. Accessed August 04, 2020. http://hdl.handle.net/1807/43692.

MLA Handbook (7th Edition):

O'Donnell, Emma. “Cardiovascular Consequences of Estrogen Deficiency: Studies in Premenopausal Women.” 2013. Web. 04 Aug 2020.

Vancouver:

O'Donnell E. Cardiovascular Consequences of Estrogen Deficiency: Studies in Premenopausal Women. [Internet] [Doctoral dissertation]. University of Toronto; 2013. [cited 2020 Aug 04]. Available from: http://hdl.handle.net/1807/43692.

Council of Science Editors:

O'Donnell E. Cardiovascular Consequences of Estrogen Deficiency: Studies in Premenopausal Women. [Doctoral Dissertation]. University of Toronto; 2013. Available from: http://hdl.handle.net/1807/43692

.