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You searched for subject:(Hypernatremia). Showing records 1 – 3 of 3 total matches.

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1. Sheyo, Ninza. Changes in selected electrolytes in adult intensive care patients at the University Teaching Hospital, Lusaka, Zambia.

Degree: 2019, University of Zimbabwe

The importance of regulating potassium and sodium levels is well recognized in most Intensive Care Units (ICU). Various institutions across the globe have found varying figures on the extent and causes of electrolytes derangements in ICUs. Some tertiary hospitals in Africa similar to the University Teaching Hospital (UTH), Lusaka, have reported prevalence’s of over 66% of the patients in ICU having multiple electrolyte abnormalities. However, the extent of electrolyte derangements in patients admitted to the Main Intensive Care Unit (MICU) at UTH, Lusaka, Zambia is unknown. This study aimed to evaluate the twenty-four-hour changes in selected electrolytes in adult patients admitted to MICU at UTH, Lusaka, Zambia. An Observational Cross-Sectional Study. Blood samples obtained from a peripheral vein in Heparinized bottles for renal function tests were measured using the Beckman Counter/Au480 (Serial: 2013102691) machine at UTH. Normal serum concentrations of sodium and potassium were considered as 135-145 and 3.5 - 4.5mmol/L, respectively. Statistical analysis was performed with Stata. A total number of one hundred (100) patients were enrolled in this study with a mean age of 36.8 (SD = 12.1). The mean value of sodium level was 136.7 (SD = 8.9) mmol/L and 139.0 (SD = 11.6) mmol/L, on admission and 24 hours post admission respectively. This difference in serum sodium level was shown to be statistically significant with a P-value = 0.005. Hypernatremia was shown to be associated with an increased risk of death (p = 0.02) in the Unit with an odds ratio of 4.3at 95% confidence interval of 1.3 to 13.9. Hyponatremia was the most prevalent electrolyte imbalance but was neither shown to be associated with mortality (P-value = 0.2) nor prolonged ICU stay at 24 hours post admission. The mean value of potassium level was 4.2 (SD = 1.1) mmol/L and 4.3 (SD = 1.1), on admission and 24 hours post admission respectively. This difference was shown to be not statistically significant (P-value = 0.6). Neither hypokalaemia (p = 0.2) nor hyperkalaemia (p = 0.1) were associated with mortality at 24 hours post admission and there was no association with duration of stay in ICU. There is a significant change in serum sodium levels after 24 hours post admission but there is no significant change in potassium level. Hyponatremia being the most prevalent. Hypernatremia remains significantly associated with mortality and therefore, correcting electrolyte imbalances in ICU patients is an urgent necessity. vi Keywords: Hypernatremia, Hyponatremia, Hypokalaemia, Hyperkalaemia, Electrolytes

Subjects/Keywords: Electrolytes derangement; Hypernatremia; Hyponatremia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Sheyo, N. (2019). Changes in selected electrolytes in adult intensive care patients at the University Teaching Hospital, Lusaka, Zambia. (Thesis). University of Zimbabwe. Retrieved from http://dspace.unza.zm/handle/123456789/6363

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Sheyo, Ninza. “Changes in selected electrolytes in adult intensive care patients at the University Teaching Hospital, Lusaka, Zambia.” 2019. Thesis, University of Zimbabwe. Accessed October 01, 2020. http://dspace.unza.zm/handle/123456789/6363.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Sheyo, Ninza. “Changes in selected electrolytes in adult intensive care patients at the University Teaching Hospital, Lusaka, Zambia.” 2019. Web. 01 Oct 2020.

Vancouver:

Sheyo N. Changes in selected electrolytes in adult intensive care patients at the University Teaching Hospital, Lusaka, Zambia. [Internet] [Thesis]. University of Zimbabwe; 2019. [cited 2020 Oct 01]. Available from: http://dspace.unza.zm/handle/123456789/6363.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sheyo N. Changes in selected electrolytes in adult intensive care patients at the University Teaching Hospital, Lusaka, Zambia. [Thesis]. University of Zimbabwe; 2019. Available from: http://dspace.unza.zm/handle/123456789/6363

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

2. Bieda, Amelia L. THE USE OF ENTERAL STERILE WATER FOR THE TREATMENTOF HYPERNATREMIAIN EXTREMELY LOW BIRTH WEIGHT INFANTS.

Degree: PhD, Nursing, 2013, Case Western Reserve University

There has been tremendous improvement in the survival rate of extremely low birth weight (ELBW) infants, but as a result, there are associated morbidities. ELBW infants are vulnerable to electrolyte imbalance, particularly hypernatremia (serum sodium value = 150 mEq/L). There are different approaches in the management of hypernatremia but little consensus as to the optimal approach. Liberal intravenous fluid administration is the standard treatment but is associated with comorbidities such as patent ductus arteriosus, bronchopulmonary dysplasia and intraventricular hemorrhage. The purpose of this prospective, randomized control trial (N=19) was to examine the use of enteral sterile water feeds as an alternative management strategy on the incidence and duration of hypernatremia; patterns in serum sodium values; magnitude of change in serum sodium values, and the relationship between the onset of hypernatremia and onset of diuresis during the first week of life. Infants in the study were = 27 weeks gestational age and = 1,100 grams birth weight. The study consisted of three groups: the control group (n=8) who received intravenous fluid; the prophylactic group (n=6) who received enteral sterile water feeds when their serum sodium value was = 145 mEq/L and the intervention group (n=5) who received enteral sterile water feeds when their serum sodium value was = 150 mEq/L. There were no statistically significant differences in the incidence, duration or magnitude of change in serum sodium values in the three groups; nor were there statistically significant differences in the onset of hypernatremia or diuresis. There were statistically significant differences when analyzing patterns of morning sodium values: from day one to two (p=.008) and day one to three (p =0.015) and from day three to (p =0.01) four and four to five (p =0.005). There was a statistically significant increase in sodium values found from day one (p=.000) to two and day two to three (p=.051)ELBW infants who received enteral sterile water feeds did not have a decrease in the incidence or duration of hypernatremia when compared to ELBW infants who did not receive ESWF. Since the sample size was small, it was not possible to identify cause and effect relationships among variables. Advisors/Committee Members: Dowling, Donna (Committee Chair).

Subjects/Keywords: Nursing; Hypernatremia; extremely low birth weight infants; sterile water feeds

…10 Table 4. Incidence and Mortality of Infants with Hypernatremia… …41 Table 7. Comparison of Hypernatremia Studies… …24. Episodes of Hypernatremia by Groups… …Hypernatremia ........................................................................116 x List of… …Mean Sodium Values by Group over 14 Time Points Figure H. Duration of Hypernatremia Figure I… 

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Bieda, A. L. (2013). THE USE OF ENTERAL STERILE WATER FOR THE TREATMENTOF HYPERNATREMIAIN EXTREMELY LOW BIRTH WEIGHT INFANTS. (Doctoral Dissertation). Case Western Reserve University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=case1363103838

Chicago Manual of Style (16th Edition):

Bieda, Amelia L. “THE USE OF ENTERAL STERILE WATER FOR THE TREATMENTOF HYPERNATREMIAIN EXTREMELY LOW BIRTH WEIGHT INFANTS.” 2013. Doctoral Dissertation, Case Western Reserve University. Accessed October 01, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=case1363103838.

MLA Handbook (7th Edition):

Bieda, Amelia L. “THE USE OF ENTERAL STERILE WATER FOR THE TREATMENTOF HYPERNATREMIAIN EXTREMELY LOW BIRTH WEIGHT INFANTS.” 2013. Web. 01 Oct 2020.

Vancouver:

Bieda AL. THE USE OF ENTERAL STERILE WATER FOR THE TREATMENTOF HYPERNATREMIAIN EXTREMELY LOW BIRTH WEIGHT INFANTS. [Internet] [Doctoral dissertation]. Case Western Reserve University; 2013. [cited 2020 Oct 01]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1363103838.

Council of Science Editors:

Bieda AL. THE USE OF ENTERAL STERILE WATER FOR THE TREATMENTOF HYPERNATREMIAIN EXTREMELY LOW BIRTH WEIGHT INFANTS. [Doctoral Dissertation]. Case Western Reserve University; 2013. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1363103838


Universidade do Estado do Rio de Janeiro

3. Renata de Souza Mendes. Avaliação da disnatremia em pacientes com indicação de suporte renal em unidades de terapia intensiva.

Degree: Master, 2014, Universidade do Estado do Rio de Janeiro

As disnatremias são os distúrbios hidroeletrolíticos mais comuns, sendo relatados em cerca de 30-40% dos pacientes hospitalizados. Quando presentes na admissão em Unidade de Tratamento Intensivo (UTI) são fatores de risco independentes de pior prognóstico, estando associadas à maior letalidade hospitalar. Mesmo disnatremias limítrofes (130 135 mEq/l na hiponatremia e 145 a 150 mEq/L na hipernatremia) têm sido associadas a um maior tempo de internação na UTI e a um aumento de letalidade hospitalar, independente da gravidade da doença de base. A concentração sérica do sódio é mantida por um fino controle, por meio da regulação renal do sal e da água. Pacientes com doença renal crônica (DRC) em tratamento conservador ou em terapia renal substitutiva, apresentam maior prevalência de disnatremia. Embora a hiponatremia seja mais frequente nessa população, o diagnóstico de hipo- ou hipernatremia tem sido associado a uma maior mortalidade. Não há relato claro na literatura da prevalência de disnatremias na injúria renal aguda (IRA), em especial nos casos mais graves, em que há indicação de suporte dialítico. O presente estudo teve como objetivos avaliar a prevalência da disnatremia e o seu impacto no prognóstico de pacientes gravemente enfermos com IRA e necessidade de suporte renal (SR) na UTI.Em um período de 44 meses (de dezembro de 2004 a julho 2008) foram incluídos de forma prospectiva todos os pacientes que iniciaram SR em 14 UTIs de 3 hospitais terciários do Rio de Janeiro. Dados clínicos e laboratoriais foram coletados prospectivamente e lançados em uma planilha eletrônica para posterior análise com o software R. Os desfechos de interesse foram letalidade na UTI e no hospital. As variáveis que, além do sódio, apresentavam associação com os desfechos de interesse na análise bivariada, foram selecionadas e incluídas no modelo de regressão logística múltipla.Um total de 772 pacientes foram incluídos no estudo. A mediana da idade foi de 75 [IIQ: 61-82 anos]; 81,5% (IC: 78,4%-84%) foram admitidos na UTI por complicações clínicas. A presença de pelo menos uma comorbidade (hipertensão, diabetes, doença coronariana, insuficiência cardíaca, doença pulmonar obstrutiva crônica ou cirrose) esteve presente em 84% dos pacientes. A maior parte dos pacientes (72,5%, IC: 69,2%-75,7%) apresentava o diagnóstico de sepse. Os principais fatores contribuinte para IRA foram sepse (72%) e isquemia/choque (66%). A mortalidade na UTI foi de 64,6% (IC: 61,1%-68%) e a hospitalar foi de 69,7% (IC: 66,3%-72,9%). O diagnóstico de disnatremia foi frequente, estando presente em 47,3% (IC: 43,7%-50,9%) dos pacientes. A hipernatremia foi significantemente mais frequente do que a hiponatremia (33,7% X 13,6%, p=0.001) na população estudada. Na análise multivariada, os pacientes mais idosos, a admissão clínica, o número de comorbidades e o número de disfunções orgânicas estiveram associados a uma maior letalidade hospitalar. Os paciente com hipernatremia grave (>155 mEq/l) apresentaram maior associação com o óbito na UTI e no hospital [odds ratio… Advisors/Committee Members: José Hermógenes Rocco Suassuna, Denizar Vianna Araujo, Sérgio Fernando Ferreira dos Santos, Eduardo Rocha, Elizabeth Regina Maccariello.

Subjects/Keywords: Disnatremia; Hiponatremia; Hipernatremia; Paciente crítico; Terapia intensiva; Dysnatremia; Hyponatremia; Hypernatremia; Critically ill patient; Intensive care; NEFROLOGIA; Insuficiência renal aguda - Tese; Hiponatremia - Teses; Hipernatremia - Teses; Unidade de tratamento intensivo - Teses; Doentes em estado crítico Teses

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Mendes, R. d. S. (2014). Avaliação da disnatremia em pacientes com indicação de suporte renal em unidades de terapia intensiva. (Masters Thesis). Universidade do Estado do Rio de Janeiro. Retrieved from http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=7352 ;

Chicago Manual of Style (16th Edition):

Mendes, Renata de Souza. “Avaliação da disnatremia em pacientes com indicação de suporte renal em unidades de terapia intensiva.” 2014. Masters Thesis, Universidade do Estado do Rio de Janeiro. Accessed October 01, 2020. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=7352 ;.

MLA Handbook (7th Edition):

Mendes, Renata de Souza. “Avaliação da disnatremia em pacientes com indicação de suporte renal em unidades de terapia intensiva.” 2014. Web. 01 Oct 2020.

Vancouver:

Mendes RdS. Avaliação da disnatremia em pacientes com indicação de suporte renal em unidades de terapia intensiva. [Internet] [Masters thesis]. Universidade do Estado do Rio de Janeiro; 2014. [cited 2020 Oct 01]. Available from: http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=7352 ;.

Council of Science Editors:

Mendes RdS. Avaliação da disnatremia em pacientes com indicação de suporte renal em unidades de terapia intensiva. [Masters Thesis]. Universidade do Estado do Rio de Janeiro; 2014. Available from: http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=7352 ;

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