subject:(Histopathology)

Addis Ababa University

1. Natnael, Teshager. PATHOLOGICAL AND SEROPREVALENCE STUDIES ON INFECTIOUS BURSAL DISEASE IN CHICKENS IN AND AROUND BAHIR DAR, NORTH WEST, ETHIOPIA.

Degree: 2015, Addis Ababa University

URL: http://etd.aau.edu.et/dspace/handle/123456789/7613

► A cross sectional study was conducted from January 2015 to May 2015 to characterize the pathological changes and to determine seroprevalence of IBD and its… (more)

▼ A cross sectional study was conducted from January 2015 to May 2015 to characterize the pathological changes and to determine seroprevalence of IBD and its associated risk factors in chickens in and around Bahir Dar. The clinical signs observed in IBD infected chickens were whitish diarrhea mixed with blood, ruffled feather, and massive death within short period. The necropsy findings were petichial hemorrhage in bursa of fabricius, kidney, thymus, spleen, thigh and pectoral muscles. Bursa of fabricius became edematous in serosa and mucosal part, whitish-creamy and atrophied as the course of the disease progressed. Kidney became pale and ureter was turgid with urate in a numbers of cases. The histopathological changes in this study revealed that edema of bursa of fabricius, formation of cystic follicles, depletion of lymphocytes, fibrosis and follicular architecture lost. Severe, moderate and mild lesion score were observed in bursa of fabricius. Infiltrations of heterophils were noted both in lymphoid and non lymphoid tissues. Depletion of lymphoid cell in germinal center of spleen and total depletion of lymphoid cells were encountered in thymus gland. The kidney tubules were filled by exudates and necrotized cuboidal cells. Sera collected from a total of 320 chickens were subjected to IELISA test and disclosed an overall prevalence of 51.56% (CI: 45.95 – 57.14) in study area. The seroprevalence of IBD among chickens showed a statistically significant difference (P<0.05) among study sites namely Andassa (72.73%), Gombat (50%), Wonjeta (47.69%), Meshenty (44.44%) and Bahir Dar (42.42%). The susceptibility of chickens to IBDV revealed a statistically significant difference (P<0.05) among different breeds where Koekoek was found more prone to IBD infection with seroprevalence of 67.11% followed by Bovans brown (57.69%), local breeds (48.31%), and Bovans white (40.28%). The seroprevalence of IBD was also significantly associated (P<0.05) with the age of chickens and among farm systems. These studies clearly indicated that IBD infection is a common and wide spread problem affecting a number of chicken breeds under different management systems and hence an urgent control intervention should be in place. Advisors/Committee Members: Dr. Hagos Ashenafi (advisor).

Subjects/Keywords: Seroprevalence; Histopathology; Chickens

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Natnael, T. (2015). PATHOLOGICAL AND SEROPREVALENCE STUDIES ON INFECTIOUS BURSAL DISEASE IN CHICKENS IN AND AROUND BAHIR DAR, NORTH WEST, ETHIOPIA. (Thesis). Addis Ababa University. Retrieved from http://etd.aau.edu.et/dspace/handle/123456789/7613

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Natnael, Teshager. “PATHOLOGICAL AND SEROPREVALENCE STUDIES ON INFECTIOUS BURSAL DISEASE IN CHICKENS IN AND AROUND BAHIR DAR, NORTH WEST, ETHIOPIA. ” 2015. Thesis, Addis Ababa University. Accessed April 18, 2021. http://etd.aau.edu.et/dspace/handle/123456789/7613.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Natnael, Teshager. “PATHOLOGICAL AND SEROPREVALENCE STUDIES ON INFECTIOUS BURSAL DISEASE IN CHICKENS IN AND AROUND BAHIR DAR, NORTH WEST, ETHIOPIA. ” 2015. Web. 18 Apr 2021.

Vancouver:

Natnael T. PATHOLOGICAL AND SEROPREVALENCE STUDIES ON INFECTIOUS BURSAL DISEASE IN CHICKENS IN AND AROUND BAHIR DAR, NORTH WEST, ETHIOPIA. [Internet] [Thesis]. Addis Ababa University; 2015. [cited 2021 Apr 18]. Available from: http://etd.aau.edu.et/dspace/handle/123456789/7613.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Natnael T. PATHOLOGICAL AND SEROPREVALENCE STUDIES ON INFECTIOUS BURSAL DISEASE IN CHICKENS IN AND AROUND BAHIR DAR, NORTH WEST, ETHIOPIA. [Thesis]. Addis Ababa University; 2015. Available from: http://etd.aau.edu.et/dspace/handle/123456789/7613

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Addis Ababa University

2. Kibruyesfa, Bayou. LESION CHARACTERIZATION, BACTERIAL ISOLATION AND VIRAL DETECTION FROM RESPIRATORY TRACT OF DROMEDARY CAMELS SLAUGHTERED AT ADDIS ABABA AKAKI MUNICIPAL ABATTOIR, ETHIOPIA .

Degree: 2015, Addis Ababa University

URL: http://etd.aau.edu.et/dspace/handle/123456789/7796

► This study was carried out with the aim of lesions characterization, bacterial isolation and identification and viral detection from lesions of respiratory system of dromedary… (more)

▼ This study was carried out with the aim of lesions characterization, bacterial isolation and identification and viral detection from lesions of respiratory system of dromedary camels slaughtered at Addis Ababa Akaki Abattoir from December 2014 to April 2015. A total of 207 camels were inspected during the study period. Of the lungs inspected, 53 (25.6%) had one or more gross lesions. Interstitial pneumonia 17 (8.2%), pulmonary emphysema 12 (5.8%), bronchopneumonia 11 (5.3%) and atelectasis 5 (2.4%) were among the most frequently detected pulmonary lesions. The difference of gross lesions frequency and distribution was not statistically significant (P>0.05) between male and female camels. However, gross lesions frequency and distribution significantly varied (P<0.05) among different age groups, lung lobes and between right and left lungs. Histologically interstitial pneumonia was characterized by thickening of intra alveolar septae; congested interstitial capillaries and interstitial infiltrations by lymphocytes and other mononuclear cells and suppurative bronchopneumonia by bronchiolar wall and peribronchiolar infiltration with inflammatory cells particularly neutrophils. Whereas, distended alveoli and collapsed alveoli were seen in tissue sections of pulmonary emphysema and atelectasis, respectively. From 53 lungs with gross lesions bacterial isolation and identification was made. A total of 70 bacterial isolates were detected on sheep blood agar plates from 50 (94.3%) of the processed lung tissues. Rhodococcus equi (20%), Aeromonas hydrophila (12.9%), Coagulase negative staphylococci (11.4%), Actinobacillus spp. (10%), Bacillus spp. (10%), Corynebacterium spp. (8.6%) Escherichia coli (7.1%) and Pasteurella spp. (5.7%) were among the major bacterial isolates. Besides, 25 lung samples with gross lesions were processed for viral propagation in tissue culture; 10/25 (40%) of them exhibited morphologic alterations (CPE) on VERO cell monolayer. The presence of virus in the samples was evidenced by rounding, sloughing and aggregation of infected VERO cells. The result of this study highlights that pulmonary lesions could be detected from camels that apparently looked healthy harbouring a number of pathogenic organisms in the lesions. Hence, further study should be conducted on the camels’ respiratory diseases and lesions. Advisors/Committee Members: Dr. Fufa Dawo (advisor).

Subjects/Keywords: Bacteria; Camel; Histopathology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Kibruyesfa, B. (2015). LESION CHARACTERIZATION, BACTERIAL ISOLATION AND VIRAL DETECTION FROM RESPIRATORY TRACT OF DROMEDARY CAMELS SLAUGHTERED AT ADDIS ABABA AKAKI MUNICIPAL ABATTOIR, ETHIOPIA . (Thesis). Addis Ababa University. Retrieved from http://etd.aau.edu.et/dspace/handle/123456789/7796

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kibruyesfa, Bayou. “LESION CHARACTERIZATION, BACTERIAL ISOLATION AND VIRAL DETECTION FROM RESPIRATORY TRACT OF DROMEDARY CAMELS SLAUGHTERED AT ADDIS ABABA AKAKI MUNICIPAL ABATTOIR, ETHIOPIA .” 2015. Thesis, Addis Ababa University. Accessed April 18, 2021. http://etd.aau.edu.et/dspace/handle/123456789/7796.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kibruyesfa, Bayou. “LESION CHARACTERIZATION, BACTERIAL ISOLATION AND VIRAL DETECTION FROM RESPIRATORY TRACT OF DROMEDARY CAMELS SLAUGHTERED AT ADDIS ABABA AKAKI MUNICIPAL ABATTOIR, ETHIOPIA .” 2015. Web. 18 Apr 2021.

Vancouver:

Kibruyesfa B. LESION CHARACTERIZATION, BACTERIAL ISOLATION AND VIRAL DETECTION FROM RESPIRATORY TRACT OF DROMEDARY CAMELS SLAUGHTERED AT ADDIS ABABA AKAKI MUNICIPAL ABATTOIR, ETHIOPIA . [Internet] [Thesis]. Addis Ababa University; 2015. [cited 2021 Apr 18]. Available from: http://etd.aau.edu.et/dspace/handle/123456789/7796.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kibruyesfa B. LESION CHARACTERIZATION, BACTERIAL ISOLATION AND VIRAL DETECTION FROM RESPIRATORY TRACT OF DROMEDARY CAMELS SLAUGHTERED AT ADDIS ABABA AKAKI MUNICIPAL ABATTOIR, ETHIOPIA . [Thesis]. Addis Ababa University; 2015. Available from: http://etd.aau.edu.et/dspace/handle/123456789/7796

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Addis Ababa University

3. Girmay, Amare. CHRONIC EFFECTS OF THE AQUEOUS LEAF EXTRACT OF Syzygium guineense ON SOME BLOOD PARAMETERS AND HISTOPATHOLOGY OF LIVER AND KIDNEY OF MICE .

Degree: 2009, Addis Ababa University

URL: http://etd.aau.edu.et/dspace/handle/123456789/6841

► Syzygium guineense is a tropical evergreen tree commonly used by traditional medicine practitioners in Ethiopia for the treatment of diarrhea. In this investigation, the histopathologic… (more)

Subjects/Keywords: guineense; histopathology; hematology; liver; kidney.

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APA (6^th Edition):

Girmay, A. (2009). CHRONIC EFFECTS OF THE AQUEOUS LEAF EXTRACT OF Syzygium guineense ON SOME BLOOD PARAMETERS AND HISTOPATHOLOGY OF LIVER AND KIDNEY OF MICE . (Thesis). Addis Ababa University. Retrieved from http://etd.aau.edu.et/dspace/handle/123456789/6841

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Girmay, Amare. “CHRONIC EFFECTS OF THE AQUEOUS LEAF EXTRACT OF Syzygium guineense ON SOME BLOOD PARAMETERS AND HISTOPATHOLOGY OF LIVER AND KIDNEY OF MICE .” 2009. Thesis, Addis Ababa University. Accessed April 18, 2021. http://etd.aau.edu.et/dspace/handle/123456789/6841.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Girmay, Amare. “CHRONIC EFFECTS OF THE AQUEOUS LEAF EXTRACT OF Syzygium guineense ON SOME BLOOD PARAMETERS AND HISTOPATHOLOGY OF LIVER AND KIDNEY OF MICE .” 2009. Web. 18 Apr 2021.

Vancouver:

Girmay A. CHRONIC EFFECTS OF THE AQUEOUS LEAF EXTRACT OF Syzygium guineense ON SOME BLOOD PARAMETERS AND HISTOPATHOLOGY OF LIVER AND KIDNEY OF MICE . [Internet] [Thesis]. Addis Ababa University; 2009. [cited 2021 Apr 18]. Available from: http://etd.aau.edu.et/dspace/handle/123456789/6841.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Girmay A. CHRONIC EFFECTS OF THE AQUEOUS LEAF EXTRACT OF Syzygium guineense ON SOME BLOOD PARAMETERS AND HISTOPATHOLOGY OF LIVER AND KIDNEY OF MICE . [Thesis]. Addis Ababa University; 2009. Available from: http://etd.aau.edu.et/dspace/handle/123456789/6841

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Addis Ababa University

4. Giorgis, Okbazgi. Assessment of Histopathology Services in Ethiopia .

Degree: 2015, Addis Ababa University

URL: http://etd.aau.edu.et/dspace/handle/123456789/7599

► Background: The scarcity of having histopathology laboratory in the nation will cause the difficulty to diagnose as well as follow up cancer diseases. Besides, the… (more)

▼ Background: The scarcity of having histopathology laboratory in the nation will cause the difficulty to diagnose as well as follow up cancer diseases. Besides, the scarcity of professionals also contributes for the lack of the service in developing countries like Ethiopia. Laboratory technicians who do not have proper training and experience are active in the current histopathology laboratories in these countries. Objective: To assess the histopathology laboratory practices in Ethiopia. Method: Cross sectional study-design, and convenient sampling method were used. Data were collected by using pretested observational checklist. The Principal Investigator (PI) collected the data in April 2015 at all histopathology laboratories in Ethiopia, which practice investigation of both biopsy and cytology, Fine Needle Aspiration Cytology (FNAC) and have set up of histopathology laboratory. The number of histopathology specimen per year computed the data by the number of pathologists and laboratory personnel in that laboratory. Data was entered and analyzed using Microsoft Excel 2010 software. Result: There were 11 histopathology laboratories who set up with equipment except Afar and Somali region where no histopathology laboratories were available. The available laboratories process and diagnose biopsy as well as FNAC. About 55% of laboratories in the country owned cryostat. All laboratories own microtome, 82% of the laboratories use automatic tissue processing and embedding machine whereas the rest use manually. All facilities use manual mounting and staining method, and 36.4% owned automatic staining machine. Grossing equipment and slide warmer table or oven is available at all facilities, whereas slide and block storage cabinet is available in 54.5% of the laboratories. The number of pathologists range between one and eight where AFGH, AGHMC, GGH have one. AHRI, KGH, GUH, ASUH, HUH, and JUSH have two. EPHI /St. Paul have four, and TASH has eight pathologists: thus the highest number of biopsies per pathologist per year was received by EPHI/St. Paul (1144), GGH (1008), and TASH (813). The highest FNAC per pathologist per year was practiced by GGH (4800), ASUH (1488), AFGH (1365), HUH (1200), and GUH (1196). The overall average numbers of biopsies and FNAC per pathologist per year were 715 and 901 respectively. Whereas the respective average numbers for histopathology xi laboratory personnel per year were 508 and 640. The lowest turnaround time (TAT) of 1 week for biopsy samples analysis was achieved by KGH and AFGH while three teaching hospitals had longer TAT of 30 days. (JUSH, HUH, ASUH) Conclusion: There is a scarcity of a histopathology laboratory set up as well as of pathologists and laboratory personnel. The available histopathology laboratories are not adequate and their distribution is concerned in Addis Ababa and major cities: besides; there is no histopathology laboratory in two regions of the country (Afar and Somali regions). Recommendation: The Federal Ministry of Health (FMoH)… Advisors/Committee Members: Aster Tsegaye ( PhD) (advisor).

Subjects/Keywords: histopathology; laboratory practices; Ethiopia.

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Giorgis, O. (2015). Assessment of Histopathology Services in Ethiopia . (Thesis). Addis Ababa University. Retrieved from http://etd.aau.edu.et/dspace/handle/123456789/7599

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Giorgis, Okbazgi. “Assessment of Histopathology Services in Ethiopia .” 2015. Thesis, Addis Ababa University. Accessed April 18, 2021. http://etd.aau.edu.et/dspace/handle/123456789/7599.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Giorgis, Okbazgi. “Assessment of Histopathology Services in Ethiopia .” 2015. Web. 18 Apr 2021.

Vancouver:

Giorgis O. Assessment of Histopathology Services in Ethiopia . [Internet] [Thesis]. Addis Ababa University; 2015. [cited 2021 Apr 18]. Available from: http://etd.aau.edu.et/dspace/handle/123456789/7599.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Giorgis O. Assessment of Histopathology Services in Ethiopia . [Thesis]. Addis Ababa University; 2015. Available from: http://etd.aau.edu.et/dspace/handle/123456789/7599

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Univerzitet u Beogradu

5. Koturović, Zoran M., 1965-. Histopatološka analiza uzoraka dobijenih inicizionom biopsijom zida suzne kese tokom spoljašnje dakriocistorinostomije.

Degree: Medicinski fakultet, 2017, Univerzitet u Beogradu

URL: https://fedorabg.bg.ac.rs/fedora/get/o:14671/bdef:Content/get

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Medicina - Oftalmologija / Medicine - Ophthalmology

Poremećaji u odvodnom sistemu suza koji dovode do opstrukcije oticanja istih čest su problem u oftalmologiji. Blokada ekskretornog… (more)

Subjects/Keywords: Lacrimal sac; histopathology; dacryocystorhinostomy

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APA (6^th Edition):

Koturović, Zoran M., 1. (2017). Histopatološka analiza uzoraka dobijenih inicizionom biopsijom zida suzne kese tokom spoljašnje dakriocistorinostomije. (Thesis). Univerzitet u Beogradu. Retrieved from https://fedorabg.bg.ac.rs/fedora/get/o:14671/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Koturović, Zoran M., 1965-. “Histopatološka analiza uzoraka dobijenih inicizionom biopsijom zida suzne kese tokom spoljašnje dakriocistorinostomije.” 2017. Thesis, Univerzitet u Beogradu. Accessed April 18, 2021. https://fedorabg.bg.ac.rs/fedora/get/o:14671/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Koturović, Zoran M., 1965-. “Histopatološka analiza uzoraka dobijenih inicizionom biopsijom zida suzne kese tokom spoljašnje dakriocistorinostomije.” 2017. Web. 18 Apr 2021.

Vancouver:

Koturović, Zoran M. 1. Histopatološka analiza uzoraka dobijenih inicizionom biopsijom zida suzne kese tokom spoljašnje dakriocistorinostomije. [Internet] [Thesis]. Univerzitet u Beogradu; 2017. [cited 2021 Apr 18]. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:14671/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Koturović, Zoran M. 1. Histopatološka analiza uzoraka dobijenih inicizionom biopsijom zida suzne kese tokom spoljašnje dakriocistorinostomije. [Thesis]. Univerzitet u Beogradu; 2017. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:14671/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Addis Ababa University

6. Assefa, Meseret. Histopathological Pattern of Central Nervous System Tumors:A 5-year retrospective study, at a Tertiary Hospital in Ethiopia.

Degree: 2019, Addis Ababa University

URL: http://etd.aau.edu.et/handle/123456789/21176

► Introduction: Central nervous system tumors are a heterogeneous group of neoplasms, they differ not only in their histomorphological features but also have a distinct biological… (more)

▼ Introduction: Central nervous system tumors are a heterogeneous group of neoplasms, they differ not only in their histomorphological features but also have a distinct biological background and disease course. CNS tumors are confined to the brain, spinal cord, meninges, cranial and Para spinal nerves, with each tumor having its own features, location, morphology, prognosis and treatment. Objective:The purpose of this study is to provide the histopathological pattern of CNS tumors in a tertiary care center in Ethiopia. Material and method: A retrospective descriptive histopathological analysis of central nervous system tumors carried out in the Postgraduate Department of Pathology in Tikur Anbessa Specialized Referral Hospital (TAH), Addis Ababa, Ethiopia. Patients data were retrieved from the archives of the department of Pathology for a period of 5 years from January 01, 2015 to August 31, 2019. Result:A total of 565 cases were analyzed and a wide range of histopathological diagnosis of CNS tumors was observed. Patients ages ranged from 2minths-80 years with a mean age of 36.9 years and a male to female ratio of 1:1.11. Majority of tumors had intracranial location (499 cases, 88.3%).Most of CNS tumors were low grade belonged to Grade I 70% followed by grade II 14. 8%. Tumors of meningeal tissue were most common 51.9% followed by neuroepithelial 24.2 %. When examining the data pertaining to specific types of tumors, most frequent type of CNS tumors was meningioma(272 cases, 48.1%) followed by astrocytoma (86 cases, 15.2%) . Conclusion:The present study thus reflects the histopathological patterns of CNS tumors from our center. Although there is availability of advanced imaging techniques at present, still histopathological examination is gold standard in their diagnosis.The conventional H & E staining is the mainstay for pathologic diagnosis, and IHC also plays a major role in differential diagnosis and improving diagnostic accuracy. Advisors/Committee Members: Girma, Yonas(MD), Associate Professor of Pathology (advisor).

Subjects/Keywords: CNS Tumors; Meningioma; Astrocytoma& Histopathology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Assefa, M. (2019). Histopathological Pattern of Central Nervous System Tumors:A 5-year retrospective study, at a Tertiary Hospital in Ethiopia. (Thesis). Addis Ababa University. Retrieved from http://etd.aau.edu.et/handle/123456789/21176

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Assefa, Meseret. “Histopathological Pattern of Central Nervous System Tumors:A 5-year retrospective study, at a Tertiary Hospital in Ethiopia. ” 2019. Thesis, Addis Ababa University. Accessed April 18, 2021. http://etd.aau.edu.et/handle/123456789/21176.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Assefa, Meseret. “Histopathological Pattern of Central Nervous System Tumors:A 5-year retrospective study, at a Tertiary Hospital in Ethiopia. ” 2019. Web. 18 Apr 2021.

Vancouver:

Assefa M. Histopathological Pattern of Central Nervous System Tumors:A 5-year retrospective study, at a Tertiary Hospital in Ethiopia. [Internet] [Thesis]. Addis Ababa University; 2019. [cited 2021 Apr 18]. Available from: http://etd.aau.edu.et/handle/123456789/21176.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Assefa M. Histopathological Pattern of Central Nervous System Tumors:A 5-year retrospective study, at a Tertiary Hospital in Ethiopia. [Thesis]. Addis Ababa University; 2019. Available from: http://etd.aau.edu.et/handle/123456789/21176

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade Estadual de Campinas

7. Rumayor Piña, Alicia, 1984-. Análise comparativa das características histológicas e imunoistoquímicas do pilomatricoma, craniofaringioma e tumor odontogênico cístico calcificante.

Degree: Faculdade de Odontologia de Piracicaba; Programa de Pós-Graduação em Estomatopatologia, 2013, Universidade Estadual de Campinas

URL: RUMAYOR PIÑA, Alicia. Análise comparativa das características histológicas e imunoistoquímicas do pilomatricoma, craniofaringioma e tumor odontogênico cístico calcificante. 2013. 87 f. Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba, Piracicaba, SP. Disponível em: <http://www.repositorio.unicamp.br/handle/REPOSIP/288359>. Acesso em: 22 ago. 2018. ; http://repositorio.unicamp.br/jspui/handle/REPOSIP/288359

►

Orientador: Oslei Paes de Almeida

Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba

Made available in DSpace on 2018-08-22T06:50:59Z (GMT). No.… (more)

▼

Orientador: Oslei Paes de Almeida

Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba

Made available in DSpace on 2018-08-22T06:50:59Z (GMT). No. of bitstreams: 1 RumayorPina_Alicia_M.pdf: 5492242 bytes, checksum: d72d6dba44229ac2e8e3d662cfee7879 (MD5) Previous issue date: 2013

Resumo: Pilomatricoma (PM), craniofaringioma (CF) e tumor odontogênico cístico calcificante (TOCC) são tumores que compartilham uma característica histopatológica marcante, a presença de células fantasmas. O objetivo deste trabalho foi analisar e comparar as características histológicas e imunoistoquímicas destas neoplasias. Foram usados 43 casos, sendo 21 PMs, 14 CFs e 8 TOCCs. A metodologia incluiu avaliação de todos os casos em cortes corados em hematoxilina e eosina, e reações imunoistoquímicas para anticorpos contra CKs AE1/AE3, 8, 14 e 19, CD138, ?-Catenina, Glut-1, D2-40, FAS e CD10. Os PMs acometeram principalmente a pele da região facial de homens com média de idade de 17 anos. Os CFs envolveram a região supraselar de pacientes na primeira e segunda década de vida. Os TOCCs predominaram na mandíbula de mulheres com média de idade de 47 anos. Microscopicamente, células basalóides, transicionais e fantasmas foram os principais tipos celulares observados nos PMs. Os CFs e TOCCs apresentaram epitélio formado por camada basal de células colunares em paliçada, região suprabasal composta por células escamosas triangulares, com aspecto semelhante ao retículo estrelado, além de regiões de células transicionais, fantasmas e agregados de células epiteliais em padrão de redemoinho. Nos PMs, as células basalóides mostraram positividade para CD138, ?-Catenina e CD10, enquanto que as células transicionais expressaram principalmente FAS. Todos os casos de CF e TOCC mostraram positividade para CK AE1/AE3 em todas as camadas do epitélio. Nos CFs, CK14 foi expressa na camada basal, e CK8 na região semelhante ao retículo estrelado. Além disto, as células transicionais mostraram expressão forte para Glut-1 e os agregados celulares em forma de redemoinho para CD10. Com relação ao TOCC, a camada basal e a região semelhante ao retículo estrelado mostraram positividade para CK14 e ?-Catenina, enquanto que as células transicionais expressaram CK19, FAS e CD10. As estruturas em padrão de redemoinho foram intensamente positivas para CKs 8, 19 e CD10. Observou-se expressão nuclear de ?-Catenina nos casos de CF e TOCC nas células transicionais e nos agregados em redemoinho. As células fantasmas mostraram expressão fraca apenas para AE1/AE3 e FAS. Em resumo, a semelhança histológica principal entre os três tumores, é a presença de células fantasmas. Apesar de apresentarem aspectos histológicos similares, as três lesões estudadas apresentam histogênese diferente. O mecanismo de formação das células fantasmas a partir das células epiteliais é difícil de ser determinado visto que há perda de expressão de praticamente todos os marcadores usados neste estudo

Pilomatricoma (PM), craniopharyngioma (CP) and…

Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS, Almeida, Oslei Paes de, 1948-, Sobrinho, Mário José Romañach Gonzalez, Vargas, Pablo Agustin.

Subjects/Keywords: Histopatologia; Imuno-histoquímica; Histopathology; Immunohistochemistry

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Rumayor Piña, Alicia, 1. (2013). Análise comparativa das características histológicas e imunoistoquímicas do pilomatricoma, craniofaringioma e tumor odontogênico cístico calcificante. (Masters Thesis). Universidade Estadual de Campinas. Retrieved from RUMAYOR PIÑA, Alicia. Análise comparativa das características histológicas e imunoistoquímicas do pilomatricoma, craniofaringioma e tumor odontogênico cístico calcificante. 2013. 87 f. Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba, Piracicaba, SP. Disponível em: <http://www.repositorio.unicamp.br/handle/REPOSIP/288359>. Acesso em: 22 ago. 2018. ; http://repositorio.unicamp.br/jspui/handle/REPOSIP/288359

Chicago Manual of Style (16^th Edition):

Rumayor Piña, Alicia, 1984-. “Análise comparativa das características histológicas e imunoistoquímicas do pilomatricoma, craniofaringioma e tumor odontogênico cístico calcificante.” 2013. Masters Thesis, Universidade Estadual de Campinas. Accessed April 18, 2021. RUMAYOR PIÑA, Alicia. Análise comparativa das características histológicas e imunoistoquímicas do pilomatricoma, craniofaringioma e tumor odontogênico cístico calcificante. 2013. 87 f. Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba, Piracicaba, SP. Disponível em: <http://www.repositorio.unicamp.br/handle/REPOSIP/288359>. Acesso em: 22 ago. 2018. ; http://repositorio.unicamp.br/jspui/handle/REPOSIP/288359.

MLA Handbook (7^th Edition):

Rumayor Piña, Alicia, 1984-. “Análise comparativa das características histológicas e imunoistoquímicas do pilomatricoma, craniofaringioma e tumor odontogênico cístico calcificante.” 2013. Web. 18 Apr 2021.

Vancouver:

Rumayor Piña, Alicia 1. Análise comparativa das características histológicas e imunoistoquímicas do pilomatricoma, craniofaringioma e tumor odontogênico cístico calcificante. [Internet] [Masters thesis]. Universidade Estadual de Campinas; 2013. [cited 2021 Apr 18]. Available from: RUMAYOR PIÑA, Alicia. Análise comparativa das características histológicas e imunoistoquímicas do pilomatricoma, craniofaringioma e tumor odontogênico cístico calcificante. 2013. 87 f. Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba, Piracicaba, SP. Disponível em: <http://www.repositorio.unicamp.br/handle/REPOSIP/288359>. Acesso em: 22 ago. 2018. ; http://repositorio.unicamp.br/jspui/handle/REPOSIP/288359.

Council of Science Editors:

Rumayor Piña, Alicia 1. Análise comparativa das características histológicas e imunoistoquímicas do pilomatricoma, craniofaringioma e tumor odontogênico cístico calcificante. [Masters Thesis]. Universidade Estadual de Campinas; 2013. Available from: RUMAYOR PIÑA, Alicia. Análise comparativa das características histológicas e imunoistoquímicas do pilomatricoma, craniofaringioma e tumor odontogênico cístico calcificante. 2013. 87 f. Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba, Piracicaba, SP. Disponível em: <http://www.repositorio.unicamp.br/handle/REPOSIP/288359>. Acesso em: 22 ago. 2018. ; http://repositorio.unicamp.br/jspui/handle/REPOSIP/288359

Michigan State University

8. Muth, Otto H. A histopathological study of the bovine kidney.

Degree: MS, 1935, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:14233

Subjects/Keywords: Cattle – Histopathology; Kidneys – Histopathology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Muth, O. H. (1935). A histopathological study of the bovine kidney. (Masters Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:14233

Chicago Manual of Style (16^th Edition):

Muth, Otto H. “A histopathological study of the bovine kidney.” 1935. Masters Thesis, Michigan State University. Accessed April 18, 2021. http://etd.lib.msu.edu/islandora/object/etd:14233.

MLA Handbook (7^th Edition):

Muth, Otto H. “A histopathological study of the bovine kidney.” 1935. Web. 18 Apr 2021.

Vancouver:

Muth OH. A histopathological study of the bovine kidney. [Internet] [Masters thesis]. Michigan State University; 1935. [cited 2021 Apr 18]. Available from: http://etd.lib.msu.edu/islandora/object/etd:14233.

Council of Science Editors:

Muth OH. A histopathological study of the bovine kidney. [Masters Thesis]. Michigan State University; 1935. Available from: http://etd.lib.msu.edu/islandora/object/etd:14233

9. Cristina Santos da Silva. Morphobiological, ultrastructural and histopathological study in sylvatic strains isolated from Triatoma vitticeps (Stal, 1859) in sylvatic strains isolated from Triatoma vitticeps (Stal, 1859) in the State of Rio de Janeiro.

Degree: 2006, Universidade Federal Rural do Rio de Janeiro

URL: http://bdtd.ufrrj.br//tde_busca/arquivo.php?codArquivo=773

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Triatoma vitticeps, espécie de hábito silvestre com distribuição geográfica restrita aos Estados do Rio de Janeiro, Espírito Santo, Minas Gerais e Bahia. Em Minas Gerais… (more)

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Triatoma vitticeps, espécie de hábito silvestre com distribuição geográfica restrita aos Estados do Rio de Janeiro, Espírito Santo, Minas Gerais e Bahia. Em Minas Gerais e Espírito Santo vêm invadindo o domicílio, e às vezes é encontrado domiciliado freqüentemente com taxas altas de infecção por Trypanosoma cruzi. O alvo deste estudo é avaliar a diversidade de parasitas em três áreas (duas no município de Santa Maria Madalena e uma em Conceição de Macabu) por parâmetros morfobiológico, biométrico, ultraestrutural e histopatológico. Sete isolados identificados como T. cruzi, foram mantidos em NNN+LIT+20% de soro fetal bovino. Estudos morfométricos e de diferenciação celular foram baseados nas formas epimastigotas e tripomastigotas obtidas nas curvas de crescimento no 4, 7, 10, 13, 17 e 20 dias para as amostras SMM32, SMM53, SMM81, SMM98, SMM100 da área A, SMM36 da área B, e SMM1da área F e extendidos do 23, 27, 30, 33, 37 e 40 para as amostras SMM36 e SMM98. O crescimento máximo foi observado no 4 dia para SMM100 (45.000 células/μl); no 7 dia para SMM53 (52.750 células/μl); no 10 dia para SMM 1 (21.000 células/μl) e SMM32 (33.125 células/μl); no 13 dia para SMM81 (46.000 células/μl l) e no 20 dia para a amostra SMM36 (54.375 células/μl). A amostra SMM32 e SMM100 apresentaram crescimento depois de um leve declínio. A taxa de metaciclogênese era menor que 30% nos isolados SMM32, SMM53, SMM100 e SMM1 e mais alto que 80% em SMM81 e SMM98. Com o aumento de dias de avaliação da curva de crescimento, a amostra SMM36 apresentou crescimento máximo no 33 dia (90.125 células/μl) declínando ao final (40 dia). Estes resultados demonstram uma diversidade no comportamento destes isolados. A morfometria foi baseada nas formas epimastigotes e tripomastigotas encontradas no 10, 17 e 20 dias da curva de crescimento, também sugere a heterogeneidade destes isolados. Embora a maioria dos dados sobre a ultraestrutura de T. cruzi tenham sido obtidos de formas epimastigotas mantidas em meio de cultura, o estudo realizado nas formas isoladas de triatomíneos mostrou as mesmas estruturas típicas presentes tais como cinetoplasto, microtúbulos subpeliculares, bolsa flagelar e axonema. A amostra SMM36 produziu uma alta mortalidade em camundongos inoculados com tripomastigotas. Os resultados histopatológicos com 10 e 60 dias após infecção mostram um intenso tropismo para músculo cardíaco e intenso infiltrado mononuclear. Estes resultados evidenciam a diversidade de parasitos que infectam espécimes de T. vitticeps, enfatizando o hábito silvestre desta espécie e a complexidade epidemiológica da região estudada.

Triatoma vitticeps is a wild species with restricted geographic distribution to the States of Rio de Janeiro, Espírito Santo, Minas Gerais and Bahia. In Minas Gerais and Espírito Santo it is invading the domicile, being found sometimes domiciliated, frequently with high rates of infection by Trypanosoma cruzi. The aim of this study is to evaluate the parasite diversity in the three sites (two in the…

Advisors/Committee Members: Nadja Lima Pinheiro.

Subjects/Keywords: histopathology; histopatologia; morfobiologia; Trypanosoma cruzi; PARASITOLOGIA; morphobiology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Silva, C. S. d. (2006). Morphobiological, ultrastructural and histopathological study in sylvatic strains isolated from Triatoma vitticeps (Stal, 1859) in sylvatic strains isolated from Triatoma vitticeps (Stal, 1859) in the State of Rio de Janeiro. (Thesis). Universidade Federal Rural do Rio de Janeiro. Retrieved from http://bdtd.ufrrj.br//tde_busca/arquivo.php?codArquivo=773

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Silva, Cristina Santos da. “Morphobiological, ultrastructural and histopathological study in sylvatic strains isolated from Triatoma vitticeps (Stal, 1859) in sylvatic strains isolated from Triatoma vitticeps (Stal, 1859) in the State of Rio de Janeiro.” 2006. Thesis, Universidade Federal Rural do Rio de Janeiro. Accessed April 18, 2021. http://bdtd.ufrrj.br//tde_busca/arquivo.php?codArquivo=773.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Silva, Cristina Santos da. “Morphobiological, ultrastructural and histopathological study in sylvatic strains isolated from Triatoma vitticeps (Stal, 1859) in sylvatic strains isolated from Triatoma vitticeps (Stal, 1859) in the State of Rio de Janeiro.” 2006. Web. 18 Apr 2021.

Vancouver:

Silva CSd. Morphobiological, ultrastructural and histopathological study in sylvatic strains isolated from Triatoma vitticeps (Stal, 1859) in sylvatic strains isolated from Triatoma vitticeps (Stal, 1859) in the State of Rio de Janeiro. [Internet] [Thesis]. Universidade Federal Rural do Rio de Janeiro; 2006. [cited 2021 Apr 18]. Available from: http://bdtd.ufrrj.br//tde_busca/arquivo.php?codArquivo=773.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Silva CSd. Morphobiological, ultrastructural and histopathological study in sylvatic strains isolated from Triatoma vitticeps (Stal, 1859) in sylvatic strains isolated from Triatoma vitticeps (Stal, 1859) in the State of Rio de Janeiro. [Thesis]. Universidade Federal Rural do Rio de Janeiro; 2006. Available from: http://bdtd.ufrrj.br//tde_busca/arquivo.php?codArquivo=773

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

10. Sudheer, N S; Dr.Rosamma,Philip. Mangrove plant Ceriops tagal as a potential source of anti White Spot Syndrome Virus preparations for Penaeus monodon.

Degree: 2009, Cochin University of Science and Technology

URL: http://dyuthi.cusat.ac.in/purl/3004

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White spot syndrome virus (WSSV) is the deadliest virus among crustaceans ever discovered having several unique and novel features. Recent developments in genomics and proteomics… (more)

Subjects/Keywords: White spot syndrome virus (WSSV); Shrimp; Histopathology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sudheer, N. S. D. R. (2009). Mangrove plant Ceriops tagal as a potential source of anti White Spot Syndrome Virus preparations for Penaeus monodon. (Thesis). Cochin University of Science and Technology. Retrieved from http://dyuthi.cusat.ac.in/purl/3004

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sudheer, N S; Dr Rosamma,Philip. “Mangrove plant Ceriops tagal as a potential source of anti White Spot Syndrome Virus preparations for Penaeus monodon.” 2009. Thesis, Cochin University of Science and Technology. Accessed April 18, 2021. http://dyuthi.cusat.ac.in/purl/3004.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sudheer, N S; Dr Rosamma,Philip. “Mangrove plant Ceriops tagal as a potential source of anti White Spot Syndrome Virus preparations for Penaeus monodon.” 2009. Web. 18 Apr 2021.

Vancouver:

Sudheer NSDR. Mangrove plant Ceriops tagal as a potential source of anti White Spot Syndrome Virus preparations for Penaeus monodon. [Internet] [Thesis]. Cochin University of Science and Technology; 2009. [cited 2021 Apr 18]. Available from: http://dyuthi.cusat.ac.in/purl/3004.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sudheer NSDR. Mangrove plant Ceriops tagal as a potential source of anti White Spot Syndrome Virus preparations for Penaeus monodon. [Thesis]. Cochin University of Science and Technology; 2009. Available from: http://dyuthi.cusat.ac.in/purl/3004

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Addis Ababa University

11. Teklehaimanot, Hadgu. The Effect of Solanum nigrum L. on Histopathology of Liver and Kidneys of Rats .

Degree: 2014, Addis Ababa University

URL: http://etd.aau.edu.et/dspace/handle/123456789/5174

► Summary Solanum nigrum L. is commonly called black nightshade that belongs to Solanaceae (potato) family. It is a fairly common herb or short-lived perennial shrub,… (more)

Subjects/Keywords: Solanum nigrum L.; Histopathology; Liver; Kidneys; Rats

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Teklehaimanot, H. (2014). The Effect of Solanum nigrum L. on Histopathology of Liver and Kidneys of Rats . (Thesis). Addis Ababa University. Retrieved from http://etd.aau.edu.et/dspace/handle/123456789/5174

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Teklehaimanot, Hadgu. “The Effect of Solanum nigrum L. on Histopathology of Liver and Kidneys of Rats .” 2014. Thesis, Addis Ababa University. Accessed April 18, 2021. http://etd.aau.edu.et/dspace/handle/123456789/5174.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Teklehaimanot, Hadgu. “The Effect of Solanum nigrum L. on Histopathology of Liver and Kidneys of Rats .” 2014. Web. 18 Apr 2021.

Vancouver:

Teklehaimanot H. The Effect of Solanum nigrum L. on Histopathology of Liver and Kidneys of Rats . [Internet] [Thesis]. Addis Ababa University; 2014. [cited 2021 Apr 18]. Available from: http://etd.aau.edu.et/dspace/handle/123456789/5174.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Teklehaimanot H. The Effect of Solanum nigrum L. on Histopathology of Liver and Kidneys of Rats . [Thesis]. Addis Ababa University; 2014. Available from: http://etd.aau.edu.et/dspace/handle/123456789/5174

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Addis Ababa University

12. Ketema, Mekonen. Evaluation of the acute and Subacute toxicity of aqueous leaves extracts of Artemisia afra on brain, heart and suprarenal gland in Swiss albino mice.

Degree: 2015, Addis Ababa University

URL: http://etd.aau.edu.et/dspace/handle/123456789/7989

► Having primary health care is a human right which is fulfilled by western country because of expansion of health infrastructure, and increased quantity and quality… (more)

▼ Having primary health care is a human right which is fulfilled by western country because of expansion of health infrastructure, and increased quantity and quality of health professionals. But many developing countries including Ethiopia are yet far from achieving this. In Ethiopia, the majority of population relay on traditional medicine as a source of health care. The most common sources of traditional medicine are plants. A.afra is one of these plants that are used to treat different aliments. The aim of the present study was to investigate the toxic effects of A.afra on brain, heart and suprarenal glands. The study was conducted at Addis Ababa University, College of Health Science, School of Medicine, Department of Anatomy & Department of Physiology from Jan, 2014 to July, 2015. The plant was collected from Bale National park in Oromia Regional State. The plant was air dried and aqueous extract was prepared. In this research a total of 54 male and female mice of 8-12 weeks of age weighing 25-30g were used. The extract was given by oral rout in both acute and subacute study. The doses for acute toxicity study were 200mg/kg, 700mg/kg, 1200mg/kg, 2200mg/kg, 3200mg/kg, 4200mg/kg and 5000mg/kg of body weight, while for subacute toxcicy study a doses of 600mg/kg(low dose) and 1800mg/kg(high dose) of body weight were used. LD50 was grounded to be greater or above 5000mg/kg which indicates that the plant is relatively safe. There were no observed signs of toxicity at the lower three doses, although mild toxicity sign was observed at the higher dose level in dose dependent manner. In the subacute study, two treatment groups 600mg/kg and 1800mg/kg and one control group containing both sexes were used. Weights of mice were measured weekly and individual mice were observed for possible toxicity sign. At the end of 28 days, the animals were scarified and organs were harvested and processed for microscopic examination. No toxicity signs were observed in all treatment groups. There were also no significant weight changes between the treated and control group. On microscopic examination of the brain, heart and suprarenal glands no sign of cellular injury was observed. From this study it can be concluded that A.afra is relatively safe in mice. Advisors/Committee Members: Mekbeb Afework(Dr.) (advisor).

Subjects/Keywords: Traditional medicine; A.afra; Toxicity study; LD50; Histopathology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ketema, M. (2015). Evaluation of the acute and Subacute toxicity of aqueous leaves extracts of Artemisia afra on brain, heart and suprarenal gland in Swiss albino mice. (Thesis). Addis Ababa University. Retrieved from http://etd.aau.edu.et/dspace/handle/123456789/7989

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ketema, Mekonen. “Evaluation of the acute and Subacute toxicity of aqueous leaves extracts of Artemisia afra on brain, heart and suprarenal gland in Swiss albino mice. ” 2015. Thesis, Addis Ababa University. Accessed April 18, 2021. http://etd.aau.edu.et/dspace/handle/123456789/7989.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ketema, Mekonen. “Evaluation of the acute and Subacute toxicity of aqueous leaves extracts of Artemisia afra on brain, heart and suprarenal gland in Swiss albino mice. ” 2015. Web. 18 Apr 2021.

Vancouver:

Ketema M. Evaluation of the acute and Subacute toxicity of aqueous leaves extracts of Artemisia afra on brain, heart and suprarenal gland in Swiss albino mice. [Internet] [Thesis]. Addis Ababa University; 2015. [cited 2021 Apr 18]. Available from: http://etd.aau.edu.et/dspace/handle/123456789/7989.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ketema M. Evaluation of the acute and Subacute toxicity of aqueous leaves extracts of Artemisia afra on brain, heart and suprarenal gland in Swiss albino mice. [Thesis]. Addis Ababa University; 2015. Available from: http://etd.aau.edu.et/dspace/handle/123456789/7989

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade Nova

13. Martins, Carla Maria Alves. Toxicological effects of a pharmaceutical, simvastatin, in Gammarus locusta: histopathological evaluation.

Degree: 2013, Universidade Nova

URL: http://www.rcaap.pt/detail.jsp?id=oai:run.unl.pt:10362/10801

►

Dissertação para obtenção do Grau de Mestre em Engenharia do Ambiente

Pharmaceuticals and their derivatives are considered emerging organic contaminants of aquatic ecosystems, mostly by… (more)

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Dissertação para obtenção do Grau de Mestre em Engenharia do Ambiente

Pharmaceuticals and their derivatives are considered emerging organic contaminants of aquatic ecosystems, mostly by inputs from domestic and hospital effluents. The toxicological risk associated to these substances results essentially from their ability to act on a specific metabolic process. These substances have been revealed toxic to aquatic organisms as well as to the human populations that depend on these ecosystems. However, the toxicity of pharmaceuticals in the environment is not yet well known, such as for simvastatin, which is a human drug used for the treatment of high levels of cholesterol. The amphipod Gammarus locusta is a species with high ecological relevance and high importance in toxicological studies, both acute and chronic. However, histopathological appraisals on these organisms are almost absent. Gammarus locusta (newborn) were exposed to a chronic assay with a broad range of sublethal concentrations of simvastatin. At the end of their life cycle, males and females were subjected to a histopathological evaluation using histochemical techniques for light bright-field and fluorescence microscopy, considering the hepatopancreas as the main target-organ. The comparison between the control treatment and the organisms exposed to several concentrations of the pharmaceutical permitted the selection and evaluation of qualitative and quantitative histopathological biomarkers. The results show non-monotonic dose-response curves that support the physiological alterations on the hepatopancreas epithelium reflecting alterations in the metabolism of carbohydrates, enzymatic activity and lipid storage. However, no evidence of severe lesions in this and other organs could be related to exposure. Females presented a higher ability to react to the pharmaceutical than males, when exposed to the lower concentrations of simvastatin. This can be connected with the higher energy reserves of females, associated in part to their reproductive functions. In conclusion, simvastatin affects amphipod metabolism that is responsible by alterations on cellular structures of the hepatopancreas, revealing thus more important physiological alterations than direct damage induced by the pharmaceutical.

Advisors/Committee Members: Costa, Maria Helena, Costa, Pedro Manuel Broa.

Subjects/Keywords: Amphipod; Pharmaceuticals; Histology; Histopathology; Toxicity bioassays; Hepatopancreas

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Martins, C. M. A. (2013). Toxicological effects of a pharmaceutical, simvastatin, in Gammarus locusta: histopathological evaluation. (Thesis). Universidade Nova. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:run.unl.pt:10362/10801

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Martins, Carla Maria Alves. “Toxicological effects of a pharmaceutical, simvastatin, in Gammarus locusta: histopathological evaluation.” 2013. Thesis, Universidade Nova. Accessed April 18, 2021. http://www.rcaap.pt/detail.jsp?id=oai:run.unl.pt:10362/10801.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Martins, Carla Maria Alves. “Toxicological effects of a pharmaceutical, simvastatin, in Gammarus locusta: histopathological evaluation.” 2013. Web. 18 Apr 2021.

Vancouver:

Martins CMA. Toxicological effects of a pharmaceutical, simvastatin, in Gammarus locusta: histopathological evaluation. [Internet] [Thesis]. Universidade Nova; 2013. [cited 2021 Apr 18]. Available from: http://www.rcaap.pt/detail.jsp?id=oai:run.unl.pt:10362/10801.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Martins CMA. Toxicological effects of a pharmaceutical, simvastatin, in Gammarus locusta: histopathological evaluation. [Thesis]. Universidade Nova; 2013. Available from: http://www.rcaap.pt/detail.jsp?id=oai:run.unl.pt:10362/10801

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

14. Starobinets, Olga. Validation of Multiparametric Magnetic Resonance Imaging Techniques for Evaluating the Prostate.

Degree: Bioengineering, 2017, University of California – San Francisco

URL: http://www.escholarship.org/uc/item/6p38157c

► Prostate cancer is extremely common. With recent advancements in cancer detection, an increasing number of men at a younger age face the difficult choice between… (more)

Subjects/Keywords: Biomedical engineering; Histopathology; Imaging; MRI; Multiparametric; Prostate

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APA (6^th Edition):

Starobinets, O. (2017). Validation of Multiparametric Magnetic Resonance Imaging Techniques for Evaluating the Prostate. (Thesis). University of California – San Francisco. Retrieved from http://www.escholarship.org/uc/item/6p38157c

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Starobinets, Olga. “Validation of Multiparametric Magnetic Resonance Imaging Techniques for Evaluating the Prostate.” 2017. Thesis, University of California – San Francisco. Accessed April 18, 2021. http://www.escholarship.org/uc/item/6p38157c.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Starobinets, Olga. “Validation of Multiparametric Magnetic Resonance Imaging Techniques for Evaluating the Prostate.” 2017. Web. 18 Apr 2021.

Vancouver:

Starobinets O. Validation of Multiparametric Magnetic Resonance Imaging Techniques for Evaluating the Prostate. [Internet] [Thesis]. University of California – San Francisco; 2017. [cited 2021 Apr 18]. Available from: http://www.escholarship.org/uc/item/6p38157c.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Starobinets O. Validation of Multiparametric Magnetic Resonance Imaging Techniques for Evaluating the Prostate. [Thesis]. University of California – San Francisco; 2017. Available from: http://www.escholarship.org/uc/item/6p38157c

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

15. Randall-Demllo, SY. Investigation of neoplastic transition of the colonic epithelium in the Winnie mouse model of spontaneous chronic colitis.

Degree: 2017, University of Tasmania

URL: https://eprints.utas.edu.au/23911/1/Randall_Demllo_whole_thesis.pdf

► Inflammatory bowel diseases (IBD) include a range of pathologies, with ulcerative colitis (UC) and Crohn’s disease (CD) representing the bulk of IBD cases. Both UC… (more)

▼ Inflammatory bowel diseases (IBD) include a range of pathologies, with ulcerative colitis (UC) and Crohn’s disease (CD) representing the bulk of IBD cases. Both UC and CD are life-long immune disorders which are the cause of significant morbidity with the incidences of both diseases increasing globally. Chronic inflammation of the colon, such as that occurring in ulcerative colitis or Crohn’s colitis is associated with an increased risk of colorectal cancer. The mechanisms responsible for the transition from chronically inflamed tissue and colorectal cancer remain largely unknown. Defects in the formation of a colonic mucous lining impermeable to bacterial penetration have been associated with inflammatory bowel diseases. Genetic ablation of the predominant gel-forming mucin in the colon, mucin-2 (Muc2), produces a chronic colitis by permitting contact between the host tissues and the micro-organisms resident within the colon. Animals with defects in mucus synthesis also display an increased incidence of intestinal tumours, the development of which may accelerated by the severity of the concomitant chronic inflammation. The present study therefore aimed to investigate the utility of using the Winnie mouse to model the progression of chronic colitis to colonic cancer. Winnie carry a homozygous missense mutation in Muc2, resulting in spontaneous colitis and ER stress due to Muc2 misfolding. Since Winnie display features of UC, we intended to characterise the molecular mechanisms mediating the transition from chronically inflamed mucosa to early pre-cancerous lesions in these animals. Administration of the colonic irritant dextran sulphate sodium (DSS) in a regimen of three, seven-day cycles in Winnie mice to simulate bouts of severe inflammation was trialled. The distal colon of Winnie mice after completion of the DSS protocol revealed hyperplastic mucosa with glandular morphological abnormalities resembling pre-cancerous change. Architectural derangement consistent with high-grade dysplasia was present in 55% of Winnie receiving DSS whereas these features were absent untreated Winnie or wild-type mice (χ(²) = 6.667, P ¡ 0.01). Penetration of crypts beyond the muscularis mucosae was observed infrequently (27% of Winnie mice after DSS) but was absent in wild-type (WT) animals irrespective of treatment. Although dysplasia-like changes were evident after the completion of five DSS cycles, cessation of DSS administration allowed a return to a uniform crypt morphology. Three cycles of DSS increased expression of Ccl5, Trp53 by 10% and 28% (P <0.05) but Cav1 decreased 44% in Winnie + DSS relative to WT + DSS. Expression of Myc was unchanged in Winnie with or without DSS, but increased in WT following three cycles of DSS. Changes in distribution of vimentin and N-cadherin were not observed in the colon of Winnie suggesting that EMT was not involved in the manifestation of the observed pathology in the Winnie colon. Though the cancerous potential of the lesions observed in Winnie was unclear, the described model may be…

Subjects/Keywords: colitis; precancer; Mucin-2; mice histopathology

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APA (6^th Edition):

Randall-Demllo, S. (2017). Investigation of neoplastic transition of the colonic epithelium in the Winnie mouse model of spontaneous chronic colitis. (Thesis). University of Tasmania. Retrieved from https://eprints.utas.edu.au/23911/1/Randall_Demllo_whole_thesis.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Randall-Demllo, SY. “Investigation of neoplastic transition of the colonic epithelium in the Winnie mouse model of spontaneous chronic colitis.” 2017. Thesis, University of Tasmania. Accessed April 18, 2021. https://eprints.utas.edu.au/23911/1/Randall_Demllo_whole_thesis.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Randall-Demllo, SY. “Investigation of neoplastic transition of the colonic epithelium in the Winnie mouse model of spontaneous chronic colitis.” 2017. Web. 18 Apr 2021.

Vancouver:

Randall-Demllo S. Investigation of neoplastic transition of the colonic epithelium in the Winnie mouse model of spontaneous chronic colitis. [Internet] [Thesis]. University of Tasmania; 2017. [cited 2021 Apr 18]. Available from: https://eprints.utas.edu.au/23911/1/Randall_Demllo_whole_thesis.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Randall-Demllo S. Investigation of neoplastic transition of the colonic epithelium in the Winnie mouse model of spontaneous chronic colitis. [Thesis]. University of Tasmania; 2017. Available from: https://eprints.utas.edu.au/23911/1/Randall_Demllo_whole_thesis.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Plymouth

16. Al-Bairuty, Genan Adnan. Histopathological effects of metal and metalic nanoparticles on the body systems of rainbow trout (Oncorhynchus mykiss).

Degree: PhD, 2013, University of Plymouth

URL: http://hdl.handle.net/10026.1/2879

► Histopathology studies of metal nanoparticles (NPs) compared to traditional forms of metal in fish are scarce. Additionally, it is unclear whether metal nanoparticles cause greater… (more)

▼ Histopathology studies of metal nanoparticles (NPs) compared to traditional forms of metal in fish are scarce. Additionally, it is unclear whether metal nanoparticles cause greater or different pathologies compared to other forms of metal. The current study aimed to assess the pathological effects of Cu-NPs and TiO2 NPs on rainbow trout via various routes of exposure and, where appropriate, to compare them to either the equivalent dissolved metal salts or bulk powder forms. The first experiment showed that waterborne exposure to Cu-NPs and CuSO4 caused similar types of organ pathologies and alteration in the spleen content, however there were some material-type effects in the incidence injuries; with Cu-NPs in some organs by causing more injury in the intestine, liver, and brain when compared to effects caused by the equivalent concentration of CuSO4. Lowering water pH did have an effect on the toxicity of Cu-NPs and dissolved Cu in trout, and the results illustrated that both Cu treatments are more toxic at pH 5 than pH 7 by causing more physiological and pathological changes, although both CuSO4 and Cu-NP treatments showed similar types of organ lesions. Waterborne exposure to TiO2 NPs and bulk forms of TiO2 showed similar types of organ pathologies and alteration in the spleen contents, but there was a material-type effect in some organs (more injury with the bulk treatment than the NP form). After 96 h following intravenous injections of bulk or TiO2 NPs in trout, organs showed similar types of pathologies; except the spleen and kidney which showed a material-type effects (more injury with NPs than the bulk forms). This could be attributed to the highest Ti accumulation from the TiO2 NP treatment in the kidney and spleens, or to the role of these organs in filtrating the circulating blood. Overall, this thesis demonstrates that metal-NPs produced similar types of organ pathologies to traditional forms of metals through different routes of exposure, but there were some material-type effects on the incidence of injuries in some organs. The results have also added some understanding on the fate, and effects of NPs by identifying the target organs involved. Some of the nano-specific effects may need to be given extra consideration in environmental and human health risk assessments.

Subjects/Keywords: 639.3; Histopathology, metal, metal nanoparticles, fish

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Al-Bairuty, G. A. (2013). Histopathological effects of metal and metalic nanoparticles on the body systems of rainbow trout (Oncorhynchus mykiss). (Doctoral Dissertation). University of Plymouth. Retrieved from http://hdl.handle.net/10026.1/2879

Chicago Manual of Style (16^th Edition):

Al-Bairuty, Genan Adnan. “Histopathological effects of metal and metalic nanoparticles on the body systems of rainbow trout (Oncorhynchus mykiss).” 2013. Doctoral Dissertation, University of Plymouth. Accessed April 18, 2021. http://hdl.handle.net/10026.1/2879.

MLA Handbook (7^th Edition):

Al-Bairuty, Genan Adnan. “Histopathological effects of metal and metalic nanoparticles on the body systems of rainbow trout (Oncorhynchus mykiss).” 2013. Web. 18 Apr 2021.

Vancouver:

Al-Bairuty GA. Histopathological effects of metal and metalic nanoparticles on the body systems of rainbow trout (Oncorhynchus mykiss). [Internet] [Doctoral dissertation]. University of Plymouth; 2013. [cited 2021 Apr 18]. Available from: http://hdl.handle.net/10026.1/2879.

Council of Science Editors:

Al-Bairuty GA. Histopathological effects of metal and metalic nanoparticles on the body systems of rainbow trout (Oncorhynchus mykiss). [Doctoral Dissertation]. University of Plymouth; 2013. Available from: http://hdl.handle.net/10026.1/2879

17. Crowley, Darragh. Cancer cell-platelet interactions in ovarian cancer metastasis.

Degree: 2012, Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy

URL: http://hdl.handle.net/2262/78868

►

THESIS 9965

Ovarian cancer is the leading cause of death from gynaecological malignancy worldwide with an estimated global incidence of 225,900 and mortality of 140,200… (more)

Subjects/Keywords: Histopathology, Ph.D.; Ph.D. Trinity College Dublin

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APA (6^th Edition):

Crowley, D. (2012). Cancer cell-platelet interactions in ovarian cancer metastasis. (Thesis). Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy. Retrieved from http://hdl.handle.net/2262/78868

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Crowley, Darragh. “Cancer cell-platelet interactions in ovarian cancer metastasis.” 2012. Thesis, Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy. Accessed April 18, 2021. http://hdl.handle.net/2262/78868.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Crowley, Darragh. “Cancer cell-platelet interactions in ovarian cancer metastasis.” 2012. Web. 18 Apr 2021.

Vancouver:

Crowley D. Cancer cell-platelet interactions in ovarian cancer metastasis. [Internet] [Thesis]. Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy; 2012. [cited 2021 Apr 18]. Available from: http://hdl.handle.net/2262/78868.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Crowley D. Cancer cell-platelet interactions in ovarian cancer metastasis. [Thesis]. Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy; 2012. Available from: http://hdl.handle.net/2262/78868

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

18. Sommerville, Gary. Non-coding RNA expression in cancer stem cell progenies derived from tumours +/-BRAF V600E mutation.

Degree: 2013, Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy

URL: http://hdl.handle.net/2262/79356

►

THESIS 10159

Cancer has placed a huge burden on the global health system and rising rates in particular cancer types such as lung cancer and… (more)

Subjects/Keywords: Histopathology, Ph.D.; Ph.D. Trinity College Dublin

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APA (6^th Edition):

Sommerville, G. (2013). Non-coding RNA expression in cancer stem cell progenies derived from tumours +/-BRAF V600E mutation. (Thesis). Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy. Retrieved from http://hdl.handle.net/2262/79356

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sommerville, Gary. “Non-coding RNA expression in cancer stem cell progenies derived from tumours +/-BRAF V600E mutation.” 2013. Thesis, Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy. Accessed April 18, 2021. http://hdl.handle.net/2262/79356.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sommerville, Gary. “Non-coding RNA expression in cancer stem cell progenies derived from tumours +/-BRAF V600E mutation.” 2013. Web. 18 Apr 2021.

Vancouver:

Sommerville G. Non-coding RNA expression in cancer stem cell progenies derived from tumours +/-BRAF V600E mutation. [Internet] [Thesis]. Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy; 2013. [cited 2021 Apr 18]. Available from: http://hdl.handle.net/2262/79356.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sommerville G. Non-coding RNA expression in cancer stem cell progenies derived from tumours +/-BRAF V600E mutation. [Thesis]. Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy; 2013. Available from: http://hdl.handle.net/2262/79356

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

19. White, Christine. HPV mRNA and p16[ink4a] / Ki-67 detection for improved diagnosis and management of cervical neoplasia in smokers.

Degree: 2012, Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy

URL: http://hdl.handle.net/2262/79394

►

THESIS 10158

Persistent infection with high risk human papillomavirus (HR HPV) is the main etiological agent in the development of cervical cancer. The use of… (more)

Subjects/Keywords: Histopathology, Ph.D.; Ph.D. Trinity College Dublin

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APA (6^th Edition):

White, C. (2012). HPV mRNA and p16[ink4a] / Ki-67 detection for improved diagnosis and management of cervical neoplasia in smokers. (Thesis). Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy. Retrieved from http://hdl.handle.net/2262/79394

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

White, Christine. “HPV mRNA and p16[ink4a] / Ki-67 detection for improved diagnosis and management of cervical neoplasia in smokers.” 2012. Thesis, Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy. Accessed April 18, 2021. http://hdl.handle.net/2262/79394.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

White, Christine. “HPV mRNA and p16[ink4a] / Ki-67 detection for improved diagnosis and management of cervical neoplasia in smokers.” 2012. Web. 18 Apr 2021.

Vancouver:

White C. HPV mRNA and p16[ink4a] / Ki-67 detection for improved diagnosis and management of cervical neoplasia in smokers. [Internet] [Thesis]. Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy; 2012. [cited 2021 Apr 18]. Available from: http://hdl.handle.net/2262/79394.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

White C. HPV mRNA and p16[ink4a] / Ki-67 detection for improved diagnosis and management of cervical neoplasia in smokers. [Thesis]. Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy; 2012. Available from: http://hdl.handle.net/2262/79394

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

20. O'Mahony, James F. Modelling the cost-effectiveness of cancer prevention : reframing models to better match policy questions.

Degree: 2013, Trinity College (Dublin, Ireland). School of Medicine. Centre of Health Policy and Management

URL: http://hdl.handle.net/2262/85256

►

THESIS 9943

This thesis comprises six papers concerning methodological issues in cost- effectiveness analysis (CEA) of healthcare interventions. The unifying theme to these studies is… (more)

Subjects/Keywords: Histopathology, Ph.D.; Ph.D. Trinity College Dublin

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APA (6^th Edition):

O'Mahony, J. F. (2013). Modelling the cost-effectiveness of cancer prevention : reframing models to better match policy questions. (Thesis). Trinity College (Dublin, Ireland). School of Medicine. Centre of Health Policy and Management. Retrieved from http://hdl.handle.net/2262/85256

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

O'Mahony, James F. “Modelling the cost-effectiveness of cancer prevention : reframing models to better match policy questions.” 2013. Thesis, Trinity College (Dublin, Ireland). School of Medicine. Centre of Health Policy and Management. Accessed April 18, 2021. http://hdl.handle.net/2262/85256.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

O'Mahony, James F. “Modelling the cost-effectiveness of cancer prevention : reframing models to better match policy questions.” 2013. Web. 18 Apr 2021.

Vancouver:

O'Mahony JF. Modelling the cost-effectiveness of cancer prevention : reframing models to better match policy questions. [Internet] [Thesis]. Trinity College (Dublin, Ireland). School of Medicine. Centre of Health Policy and Management; 2013. [cited 2021 Apr 18]. Available from: http://hdl.handle.net/2262/85256.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

O'Mahony JF. Modelling the cost-effectiveness of cancer prevention : reframing models to better match policy questions. [Thesis]. Trinity College (Dublin, Ireland). School of Medicine. Centre of Health Policy and Management; 2013. Available from: http://hdl.handle.net/2262/85256

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

21. Kelly, Lorna Catherine-Noelle. Post-transcriptional Dysregulation by microRNAs is implicated in the Pathogenesis of Gastrointestinal Stromal Tumour [GIST].

Degree: 2013, Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy

URL: http://hdl.handle.net/2262/79069

►

THESIS 10138

In a cohort of 73 GISTs including adult mutant, adult wild-type and paediatric cases miRNA expression was examined using TaqMan? Low Density Arrays… (more)

Subjects/Keywords: Histopathology, Ph.D.; Ph.D. Trinity College Dublin

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APA (6^th Edition):

Kelly, L. C. (2013). Post-transcriptional Dysregulation by microRNAs is implicated in the Pathogenesis of Gastrointestinal Stromal Tumour [GIST]. (Thesis). Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy. Retrieved from http://hdl.handle.net/2262/79069

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kelly, Lorna Catherine-Noelle. “Post-transcriptional Dysregulation by microRNAs is implicated in the Pathogenesis of Gastrointestinal Stromal Tumour [GIST].” 2013. Thesis, Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy. Accessed April 18, 2021. http://hdl.handle.net/2262/79069.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kelly, Lorna Catherine-Noelle. “Post-transcriptional Dysregulation by microRNAs is implicated in the Pathogenesis of Gastrointestinal Stromal Tumour [GIST].” 2013. Web. 18 Apr 2021.

Vancouver:

Kelly LC. Post-transcriptional Dysregulation by microRNAs is implicated in the Pathogenesis of Gastrointestinal Stromal Tumour [GIST]. [Internet] [Thesis]. Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy; 2013. [cited 2021 Apr 18]. Available from: http://hdl.handle.net/2262/79069.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kelly LC. Post-transcriptional Dysregulation by microRNAs is implicated in the Pathogenesis of Gastrointestinal Stromal Tumour [GIST]. [Thesis]. Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy; 2013. Available from: http://hdl.handle.net/2262/79069

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

22. Walsh, Kathryn Jane. Prognosis of resected, early-stage, lung adenocarcinoma patients.

Degree: PhD, 2018, University of Edinburgh

URL: http://hdl.handle.net/1842/28992

► Lung cancer is the leading cause of cancer related death worldwide; despite recent treatment developments survival rates remain poor and are closely related to the… (more)

▼ Lung cancer is the leading cause of cancer related death worldwide; despite recent treatment developments survival rates remain poor and are closely related to the patient’s clinical stage. Even among patients with early-stage lung cancer, which is amenable to surgical resection, prognosis is highly variable; some go on to live disease-free for many years whereas others quickly recur. Although post-operative chemotherapy is available it has associated morbidities and it is unclear which patients would benefit; therefore, there is a need for more effective stratification of patients. The adenocarcinoma sub-type of lung cancer is known to be morphologically heterogeneous however the majority of observed growth patterns, assessed by light microscopy, can be characterised into one of five formations: lepidic, papillary, acinar, solid and micropapillary. The morphology of each tumour has been proposed as a marker of prognosis and several studies have published a link between the most prevalent growth pattern and prognosis; suggesting those with predominantly solid or micropapillary tumours to have the least favourable outcomes. Indeed, it is now recommended that the proportion of each growth pattern and the predominant growth pattern should be reported for all resected lung adenocarcinomas; although no differential treatments have been recommended based on this assessment. The aim of this study was to determine whether combining the analysis of clinicopathological; morphological; and candidate protein, molecular genetic and transcriptomic characteristics in a single cohort of 208 early-stage, resected, adenocarcinomas with clinical follow-up could be used to identify a subset of patients at high risk of recurrence. Comprehensive morphological analysis was carried out including the presence, proportion and number of individual growth patterns; the predominant growth pattern as well as features previously associated with tumour grade (the presence of large numbers of mitotic figures, apoptotic bodies, inflammatory cells, prominent nucleoli, pleomorphic tumour cells, dyscohesive tumour cells and large amounts of necrosis and scar tissue within the tumour). In addition, gene expression was assessed using a panel of 31 cell-cycle related genes, EGFR and KRAS mutation status was determined, and EGFR and TTF1 protein expression investigated. In this study the predominant growth pattern defined by histopathology showed no ability to identify a group of patients with a poorer prognosis either in univariable or multivariable analysis. Univariable analysis identified nodal status [hazard ratio of N1 compared to N0 was 2.16 (95% CI 1.48 to 3.16, p< 0.0005)], clinical stage [hazard ratios of stage IIa and IIb compared to stage Ia were 3.15 (95% CI 1.73 to 5.73, p< 0.0005) and 2.22 (95% CI 1.10 to 4.48, p= 0.025) respectively], the presence of a significant amount of the papillary growth pattern [the hazard ratio of those with less than 8.5% papillary pattern was 0.657 (95% CI 0.44 to 0.98, p= 0.035)], and overall tumour grade score…

Subjects/Keywords: lung cancer; adenocarcinoma; morphology; prognosis; histopathology

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APA (6^th Edition):

Walsh, K. J. (2018). Prognosis of resected, early-stage, lung adenocarcinoma patients. (Doctoral Dissertation). University of Edinburgh. Retrieved from http://hdl.handle.net/1842/28992

Chicago Manual of Style (16^th Edition):

Walsh, Kathryn Jane. “Prognosis of resected, early-stage, lung adenocarcinoma patients.” 2018. Doctoral Dissertation, University of Edinburgh. Accessed April 18, 2021. http://hdl.handle.net/1842/28992.

MLA Handbook (7^th Edition):

Walsh, Kathryn Jane. “Prognosis of resected, early-stage, lung adenocarcinoma patients.” 2018. Web. 18 Apr 2021.

Vancouver:

Walsh KJ. Prognosis of resected, early-stage, lung adenocarcinoma patients. [Internet] [Doctoral dissertation]. University of Edinburgh; 2018. [cited 2021 Apr 18]. Available from: http://hdl.handle.net/1842/28992.

Council of Science Editors:

Walsh KJ. Prognosis of resected, early-stage, lung adenocarcinoma patients. [Doctoral Dissertation]. University of Edinburgh; 2018. Available from: http://hdl.handle.net/1842/28992

University of Georgia

23. Sutherland, Kathryn Patterson. Etiology and histopathology of the white pox disease of the Caribbean elkhorn coral Acropora palmata.

Degree: 2014, University of Georgia

URL: http://hdl.handle.net/10724/21381

► White pox is a lethal disease of the Caribbean elkhorn coral, Acropora palmata. White pox was first reported in 1996 in the Florida Keys, and… (more)

▼ White pox is a lethal disease of the Caribbean elkhorn coral, Acropora palmata. White pox was first reported in 1996 in the Florida Keys, and has since been observed throughout the Caribbean. Annual photographic monitoring at eight coral reef sites in the Florida Keys showed that A. palmata populations with white pox disease signs sustained losses averaging 87% between 1996 and 2002. Rate of tissue loss associated with white pox is rapid, averaging 2.5 cm2'day"l, and is greatest during periods of seasonally elevated temperature and rainfall. The etiology of white pox was determined t rough examination of surface mucopolysaccharide layers (SML) from white pox- affected and unaffected corals collected on reefs throughout the Caribbean. Metabolic profiles of pure bacterial strains isolated from SML were used to identify potential pathogens. Potential pathogens were experimentally inoculated onto healthy A. palmata. Corals inoculated with isolate PDL l00 showed white pox signs, and PDL lOO was reisolated from these corals (satisfying Koch's postulates). 16S rDNA gene sequence analyses of PDL 100 demonstrated a 100% identity to the enterobacterium Serratia marcescens. The source of the S. marcescens strain that causes white pox is uncertain. This study begins the search for the origin of the pathogen through the screening of seawater collected in the Florida Keys using biochemical and restriction analyses. Thirteen bacterial isolates were identified as putatively belonging to the genus Serratia, and the majority of these isolates were from stations where human fecal contamination of seawater is probable. White pox-affected and apparently healthy oral tissues were collected from white pox- diseased colonies of Acropora palmata in the Florida Keys. Tissues were processed for histopathology with light microscopy. White pox i associated with rounding of granular gland cells, necrosis, and atrophy. Most lesions were, concentrated in the coenosarc tissue. Cellular and tissue degeneration, however, was observed in other apparently healthy and diseased coral tissues, and there was no significant difference ,in the number or type of abnormalities present in diseased versus apparently healthy specimens. 'The e similarities may indicate that colonies affected by white pox sustain a whole-colony reaction to infection.

Subjects/Keywords: Coral; Disease; Acropora palmata; Serratia marcescens; Histopathology

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APA (6^th Edition):

Sutherland, K. P. (2014). Etiology and histopathology of the white pox disease of the Caribbean elkhorn coral Acropora palmata. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/21381

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sutherland, Kathryn Patterson. “Etiology and histopathology of the white pox disease of the Caribbean elkhorn coral Acropora palmata.” 2014. Thesis, University of Georgia. Accessed April 18, 2021. http://hdl.handle.net/10724/21381.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sutherland, Kathryn Patterson. “Etiology and histopathology of the white pox disease of the Caribbean elkhorn coral Acropora palmata.” 2014. Web. 18 Apr 2021.

Vancouver:

Sutherland KP. Etiology and histopathology of the white pox disease of the Caribbean elkhorn coral Acropora palmata. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Apr 18]. Available from: http://hdl.handle.net/10724/21381.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sutherland KP. Etiology and histopathology of the white pox disease of the Caribbean elkhorn coral Acropora palmata. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/21381

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Virginia Tech

24. Tyler, Ronald Dale Jr. Evaluation of a Paratuberculosis Quantitative Polymerase Chain Reaction Assay with Microscopic Correlation.

Degree: MS, Veterinary Medical Sciences, 2012, Virginia Tech

URL: http://hdl.handle.net/10919/41736

► Paratuberculosis is an intestinal condition in ruminants infected with Mycobacterium avium subspecies paratuberculosis (MAP) and precedes Johneâ s disease, a chronic enteric disorder in ruminants… (more)

Subjects/Keywords: Johneâ s disease; paratuberculosis; histopathology; qPCR

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APA (6^th Edition):

Tyler, R. D. J. (2012). Evaluation of a Paratuberculosis Quantitative Polymerase Chain Reaction Assay with Microscopic Correlation. (Masters Thesis). Virginia Tech. Retrieved from http://hdl.handle.net/10919/41736

Chicago Manual of Style (16^th Edition):

Tyler, Ronald Dale Jr. “Evaluation of a Paratuberculosis Quantitative Polymerase Chain Reaction Assay with Microscopic Correlation.” 2012. Masters Thesis, Virginia Tech. Accessed April 18, 2021. http://hdl.handle.net/10919/41736.

MLA Handbook (7^th Edition):

Tyler, Ronald Dale Jr. “Evaluation of a Paratuberculosis Quantitative Polymerase Chain Reaction Assay with Microscopic Correlation.” 2012. Web. 18 Apr 2021.

Vancouver:

Tyler RDJ. Evaluation of a Paratuberculosis Quantitative Polymerase Chain Reaction Assay with Microscopic Correlation. [Internet] [Masters thesis]. Virginia Tech; 2012. [cited 2021 Apr 18]. Available from: http://hdl.handle.net/10919/41736.

Council of Science Editors:

Tyler RDJ. Evaluation of a Paratuberculosis Quantitative Polymerase Chain Reaction Assay with Microscopic Correlation. [Masters Thesis]. Virginia Tech; 2012. Available from: http://hdl.handle.net/10919/41736

Oklahoma State University

25. Key, Charlotte Elise. Extrusion as a Mechanism of Host Immune Response Evasion in a Chlamydia trachomatis Murine Infection Model.

Degree: Integrative Biology, 2019, Oklahoma State University

URL: http://hdl.handle.net/11244/323407

► Chlamydia trachomatis is an obligate intracellular organism that is the leading cause of preventable blindness and sexually transmitted bacterial infections. C. trachomatis exhibits a biphasic… (more)

▼ Chlamydia trachomatis is an obligate intracellular organism that is the leading cause of preventable blindness and sexually transmitted bacterial infections. C. trachomatis exhibits a biphasic developmental cycle involving infectious elementary bodies (EB) and non-infectious, replicative reticulate bodies (RBs). At the end of its developmental cycle, EBs disseminate to neighboring cells either via host cell lysis or a novel mechanism of exit, called extrusion. It has been hypothesized that extrusions serve as a means of immune response evasion due to enclosure within host membrane. In addition, extrusions filled with multiple EBs may serve as a mode for high dose delivery of infectious organisms to tissues, rather than individual EBs from lysed host cells. Herein, female mice were intra-vaginally infected with either a C. trachomatis serovar L2 wild type strain or a mutant strain containing a silenced CT228 gene, which produces significantly more extrusions in vitro, relative to the wild type. All mice were characterized for, i.) time course of infection, ii.) systemic and mucosal immune response to infection, iii.) degree of reproductive tissue damage following clearance of infection, and iv.) recruitment of different immune cell types to reproductive tracts. In comparison to the wild-type strain, mice infected with the mutant strain revealed an increase in the time needed to clear infection, a reduction in the systemic anti-Chlamydia antibodies, and a decrease in mucous production. However, there were no significant differences amongst the concentrations of immune cells recruited to the reproductive tracts. These data may suggest that EB antigen within extrusions dampen recognition by the immune system. Therefore, further research is warranted to quantitate cytokine concentrations, to examine antigen presentation, and to examine the development of protective immunity. Advisors/Committee Members: Shaw, Jennifer H. (advisor), Lutter, Erika I. (committee member), Wozniak, Karen L. (committee member).

Subjects/Keywords: chlamydia; evasion; extrusion; histopathology; immune response; murine

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APA (6^th Edition):

Key, C. E. (2019). Extrusion as a Mechanism of Host Immune Response Evasion in a Chlamydia trachomatis Murine Infection Model. (Thesis). Oklahoma State University. Retrieved from http://hdl.handle.net/11244/323407

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Key, Charlotte Elise. “Extrusion as a Mechanism of Host Immune Response Evasion in a Chlamydia trachomatis Murine Infection Model.” 2019. Thesis, Oklahoma State University. Accessed April 18, 2021. http://hdl.handle.net/11244/323407.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Key, Charlotte Elise. “Extrusion as a Mechanism of Host Immune Response Evasion in a Chlamydia trachomatis Murine Infection Model.” 2019. Web. 18 Apr 2021.

Vancouver:

Key CE. Extrusion as a Mechanism of Host Immune Response Evasion in a Chlamydia trachomatis Murine Infection Model. [Internet] [Thesis]. Oklahoma State University; 2019. [cited 2021 Apr 18]. Available from: http://hdl.handle.net/11244/323407.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Key CE. Extrusion as a Mechanism of Host Immune Response Evasion in a Chlamydia trachomatis Murine Infection Model. [Thesis]. Oklahoma State University; 2019. Available from: http://hdl.handle.net/11244/323407

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Kent State University

26. Vignos, Megan C. A HISTOPATHOLOGICAL AND MAGNETIC RESONANCE IMAGING ASSESSMENT OF MYELOCORTICAL MULTIPLE SCLEROSIS: A NEW PATHOLOGICAL VARIANT.

Degree: PhD, College of Arts and Sciences / School of Biomedical Sciences, 2016, Kent State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=kent1461528682

► Multiple sclerosis (MS) is an inflammatory-mediated demyelinating, neurodegenerative disease characterized by a diverse clinical course and varying patterns of disease progression. It affects millions of… (more)

Subjects/Keywords: Biomedical Research; Multiple Sclerosis, Histopathology, MRI, Neurodegeneration

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APA (6^th Edition):

Vignos, M. C. (2016). A HISTOPATHOLOGICAL AND MAGNETIC RESONANCE IMAGING ASSESSMENT OF MYELOCORTICAL MULTIPLE SCLEROSIS: A NEW PATHOLOGICAL VARIANT. (Doctoral Dissertation). Kent State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=kent1461528682

Chicago Manual of Style (16^th Edition):

Vignos, Megan C. “A HISTOPATHOLOGICAL AND MAGNETIC RESONANCE IMAGING ASSESSMENT OF MYELOCORTICAL MULTIPLE SCLEROSIS: A NEW PATHOLOGICAL VARIANT.” 2016. Doctoral Dissertation, Kent State University. Accessed April 18, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=kent1461528682.

MLA Handbook (7^th Edition):

Vignos, Megan C. “A HISTOPATHOLOGICAL AND MAGNETIC RESONANCE IMAGING ASSESSMENT OF MYELOCORTICAL MULTIPLE SCLEROSIS: A NEW PATHOLOGICAL VARIANT.” 2016. Web. 18 Apr 2021.

Vancouver:

Vignos MC. A HISTOPATHOLOGICAL AND MAGNETIC RESONANCE IMAGING ASSESSMENT OF MYELOCORTICAL MULTIPLE SCLEROSIS: A NEW PATHOLOGICAL VARIANT. [Internet] [Doctoral dissertation]. Kent State University; 2016. [cited 2021 Apr 18]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=kent1461528682.

Council of Science Editors:

Vignos MC. A HISTOPATHOLOGICAL AND MAGNETIC RESONANCE IMAGING ASSESSMENT OF MYELOCORTICAL MULTIPLE SCLEROSIS: A NEW PATHOLOGICAL VARIANT. [Doctoral Dissertation]. Kent State University; 2016. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=kent1461528682

Universidade Estadual de Campinas

27. Dias, Arethusa Ingrid de Liz Medeiros, 1982-. Aspectos histopatológicos da polipose nasossinusal pré e pós corticoterapia tópica.

Degree: Faculdade de Ciências Médicas; Programa de Pós-Graduação em Ciências Médicas, 2013, Universidade Estadual de Campinas

URL: DIAS, Arethusa Ingrid de Liz Medeiros. Aspectos histopatológicos da polipose nasossinusal pré e pós corticoterapia tópica. 2013. 62 f. Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas, Campinas, SP. Disponível em: <http://www.repositorio.unicamp.br/handle/REPOSIP/308576>. Acesso em: 23 ago. 2018. ; http://repositorio.unicamp.br/jspui/handle/REPOSIP/308576

►

Orientadores: Carlos Takahiro Chone, Eulalia Sakano

Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas

Made available in DSpace on 2018-08-23T21:36:35Z (GMT). No.… (more)

▼

Orientadores: Carlos Takahiro Chone, Eulalia Sakano

Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas

Made available in DSpace on 2018-08-23T21:36:35Z (GMT). No. of bitstreams: 1 Dias_ArethusaIngriddeLizMedeiros_M.pdf: 1854166 bytes, checksum: ba03fb9925b6895d98d898626cbb0986 (MD5) Previous issue date: 2013

Resumo: Existem poucos estudos que correlacionam os aspectos histopatológicos dos pólipos nasossinusais após tratamento com corticosteróide nasal. O objetivo do presente estudo foi analisar as alterações histopatológicas dos pólipos nasais antes e após o uso de corticosteróide tópico nasal por três meses. Foi utilizado ensaio clínico, sem grupo controle. Biópsias de pólipos nasais de pacientes com polipose nasossinusal foram realizadas antes e após três meses de uso de budesonida 50 mcg, duas vezes ao dia, para análise histopatológica. Nos 35 pacientes incluídos, observou-se, após corticoterapia, um aumento da intensidade do edema na submucosa, sendo que 50% destes apresentavam edema intenso, uma redução de 47% de pacientes com infiltrado intenso de eosinófilos (p= 0,07) e não houve alteração quanto ao infiltrado de linfócitos, neutrófilos e plasmócitos. Com relação à presença dos cistos glandulares, houve aumento estatisticamente significante (p=0,031). Não se observou variação na espessura da membrana basal (p=0,344). Concluiu-se que o uso de corticosteróide tópico nasal por três meses mostrou variações no estroma e na intensidade das células dos pólipos nasossinusais

There are few papers regarding the effect of corticosteroids on histopathology of sinonasal polyps. The aim of this study was to analyze the histopathology of nasal polyps before and after three months of nasal topical corticosteroids. It was used a non-controlled clinical trial. Nasal polyps biopsies of patients with sinonasal polyposis were performed before and after three months of budesonide 50 mcg BID for histopathological analysis. Among the 35 patients included, after steroid therapy, it was observed an increase in submucosal edema intensity, half of them presenting intense edema, a 47% reduction of cases with intense eosinophils infiltration (p = 0.07). Lymphocytes, neutrophils and plasma cells infiltration in polyps was not altered by treatment. It was observed statistically significant increase in presence of glandular cysts after treatment (p = 0.031). The thickness of the basement membrane did not changes (p=0.344). This study concluded that three months use of topical nasal corticosteroids resulted in stromal and cellular variations of sinonasal polyps

Mestrado

Otorrinolaringologia

Mestra em Ciências Médicas

Advisors/Committee Members: UNIVERSIDADE ESTADUAL DE CAMPINAS, Sakano, Eulalia, 1950-, Chone, Carlos Takahiro, 1968-, Kosugi, Eduardo Makoto, Crespo, Agrício Nubiato.

Subjects/Keywords: Biópsia; Corticosteroides; Histopatologia; Biopsy; Corticosteroid; Histopathology

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APA (6^th Edition):

Dias, Arethusa Ingrid de Liz Medeiros, 1. (2013). Aspectos histopatológicos da polipose nasossinusal pré e pós corticoterapia tópica. (Masters Thesis). Universidade Estadual de Campinas. Retrieved from DIAS, Arethusa Ingrid de Liz Medeiros. Aspectos histopatológicos da polipose nasossinusal pré e pós corticoterapia tópica. 2013. 62 f. Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas, Campinas, SP. Disponível em: <http://www.repositorio.unicamp.br/handle/REPOSIP/308576>. Acesso em: 23 ago. 2018. ; http://repositorio.unicamp.br/jspui/handle/REPOSIP/308576

Chicago Manual of Style (16^th Edition):

Dias, Arethusa Ingrid de Liz Medeiros, 1982-. “Aspectos histopatológicos da polipose nasossinusal pré e pós corticoterapia tópica.” 2013. Masters Thesis, Universidade Estadual de Campinas. Accessed April 18, 2021. DIAS, Arethusa Ingrid de Liz Medeiros. Aspectos histopatológicos da polipose nasossinusal pré e pós corticoterapia tópica. 2013. 62 f. Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas, Campinas, SP. Disponível em: <http://www.repositorio.unicamp.br/handle/REPOSIP/308576>. Acesso em: 23 ago. 2018. ; http://repositorio.unicamp.br/jspui/handle/REPOSIP/308576.

MLA Handbook (7^th Edition):

Dias, Arethusa Ingrid de Liz Medeiros, 1982-. “Aspectos histopatológicos da polipose nasossinusal pré e pós corticoterapia tópica.” 2013. Web. 18 Apr 2021.

Vancouver:

Dias, Arethusa Ingrid de Liz Medeiros 1. Aspectos histopatológicos da polipose nasossinusal pré e pós corticoterapia tópica. [Internet] [Masters thesis]. Universidade Estadual de Campinas; 2013. [cited 2021 Apr 18]. Available from: DIAS, Arethusa Ingrid de Liz Medeiros. Aspectos histopatológicos da polipose nasossinusal pré e pós corticoterapia tópica. 2013. 62 f. Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas, Campinas, SP. Disponível em: <http://www.repositorio.unicamp.br/handle/REPOSIP/308576>. Acesso em: 23 ago. 2018. ; http://repositorio.unicamp.br/jspui/handle/REPOSIP/308576.

Council of Science Editors:

Dias, Arethusa Ingrid de Liz Medeiros 1. Aspectos histopatológicos da polipose nasossinusal pré e pós corticoterapia tópica. [Masters Thesis]. Universidade Estadual de Campinas; 2013. Available from: DIAS, Arethusa Ingrid de Liz Medeiros. Aspectos histopatológicos da polipose nasossinusal pré e pós corticoterapia tópica. 2013. 62 f. Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas, Campinas, SP. Disponível em: <http://www.repositorio.unicamp.br/handle/REPOSIP/308576>. Acesso em: 23 ago. 2018. ; http://repositorio.unicamp.br/jspui/handle/REPOSIP/308576

University of the Western Cape

28. Wurdeman, Bret Mark. The evaluation and development of diagnostic tools for the detection of ichthyophonus hoferi in fish host tissue samples .

Degree: 2019, University of the Western Cape

URL: http://hdl.handle.net/11394/7868

► Ichthyophonus hoferi is a highly pathogenic histozoic parasite that has low host specificity capable of producing mass mortalities of epizootic proportions in marine commercial fish… (more)

Subjects/Keywords: Disease; Diagnostics; Ichthyophonus hoferi; DNA extraction; Histopathology

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APA (6^th Edition):

Wurdeman, B. M. (2019). The evaluation and development of diagnostic tools for the detection of ichthyophonus hoferi in fish host tissue samples . (Thesis). University of the Western Cape. Retrieved from http://hdl.handle.net/11394/7868

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Wurdeman, Bret Mark. “The evaluation and development of diagnostic tools for the detection of ichthyophonus hoferi in fish host tissue samples .” 2019. Thesis, University of the Western Cape. Accessed April 18, 2021. http://hdl.handle.net/11394/7868.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Wurdeman, Bret Mark. “The evaluation and development of diagnostic tools for the detection of ichthyophonus hoferi in fish host tissue samples .” 2019. Web. 18 Apr 2021.

Vancouver:

Wurdeman BM. The evaluation and development of diagnostic tools for the detection of ichthyophonus hoferi in fish host tissue samples . [Internet] [Thesis]. University of the Western Cape; 2019. [cited 2021 Apr 18]. Available from: http://hdl.handle.net/11394/7868.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Wurdeman BM. The evaluation and development of diagnostic tools for the detection of ichthyophonus hoferi in fish host tissue samples . [Thesis]. University of the Western Cape; 2019. Available from: http://hdl.handle.net/11394/7868

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Helsinki

29. Verkola, Marie. Histopathological features of the glandular mucosa of the normal equine stomach and comparison with lesions in a horse with equine glandular gastritis-erosion syndrome (EGGES).

Degree: Department of Equine and Small Animal Medicine; Helsingin yliopisto, Eläinlääketieteellinen tiedekunta, Kliinisen hevos- ja pieneläinlääketieteen osasto; Helsingfors universitet, Veterinärmedicinska fakulteten, Avdelningen för klinisk häst- och smådjursmedicin, 2014, University of Helsinki

URL: http://hdl.handle.net/10138/135180

► Research on lesions in the equine stomach has concentrated mainly on equine gastric ulcer syndrome (EGUS). Lesions in the glandular area of the antrum and… (more)

Subjects/Keywords: equine; gastric ulcer; histopathology; hevonen; mahahaava; histologia; Hevosten sisätaudit; Hästar internmedicin; Equine Internal Medicine; equine; gastric ulcer; histopathology

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APA (6^th Edition):

Verkola, M. (2014). Histopathological features of the glandular mucosa of the normal equine stomach and comparison with lesions in a horse with equine glandular gastritis-erosion syndrome (EGGES). (Thesis). University of Helsinki. Retrieved from http://hdl.handle.net/10138/135180

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Verkola, Marie. “Histopathological features of the glandular mucosa of the normal equine stomach and comparison with lesions in a horse with equine glandular gastritis-erosion syndrome (EGGES).” 2014. Thesis, University of Helsinki. Accessed April 18, 2021. http://hdl.handle.net/10138/135180.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Verkola, Marie. “Histopathological features of the glandular mucosa of the normal equine stomach and comparison with lesions in a horse with equine glandular gastritis-erosion syndrome (EGGES).” 2014. Web. 18 Apr 2021.

Vancouver:

Verkola M. Histopathological features of the glandular mucosa of the normal equine stomach and comparison with lesions in a horse with equine glandular gastritis-erosion syndrome (EGGES). [Internet] [Thesis]. University of Helsinki; 2014. [cited 2021 Apr 18]. Available from: http://hdl.handle.net/10138/135180.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Verkola M. Histopathological features of the glandular mucosa of the normal equine stomach and comparison with lesions in a horse with equine glandular gastritis-erosion syndrome (EGGES). [Thesis]. University of Helsinki; 2014. Available from: http://hdl.handle.net/10138/135180

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Houston

30. Mathew, Jessica 1978-. MORPHOMETRIC HISTOPATHOLOGY OF THE PHYSIOLOGICALLY FIXED KERATOCONIC CORNEA.

Degree: PhD, Physiological Optics and Vision Science, 2010, University of Houston

URL: http://hdl.handle.net/10657/424

► Purpose: Clinically, keratoconus is a condition associated with corneal ectasia, thinning, steepening and scarring, and sometimes necessitates transplant surgery. Exactly where this corneal pathology starts,… (more)

▼ Purpose: Clinically, keratoconus is a condition associated with corneal ectasia, thinning, steepening and scarring, and sometimes necessitates transplant surgery. Exactly where this corneal pathology starts, what structures are involved and what is lost in the thinning process is poorly defined in literature. The purpose of this study was to investigate the etiology, pathophysiology and the structural collapse leading to ectasia by utilizing a histopathological approach. Methods: A total of 15 surgically removed keratoconic corneas and 7 eye bank control corneas were used. The corneas were fixed in 2% glutaraldehyde in 80mM sodium cacodylate (pH 7.4, 320 to 340 mOsm/kg) and prepared for transverse sectioning with light (Olympus BX51 digital) and transmission electron microscopy (Jeol 100C, initially, and the Tecnai G2 12 twin). Serial electron micrographs were taken of the geometric center of normal corneas and the central cone region of keratoconic corneas. Montages were created for full stromal thickness lamellar counts and for assessment of the anterior limiting lamina (ALL)/stromal interface. Lamellar counts adhered to a specific set of criteria, while a morphometric approach was utilized to define the features of the ALL/stromal interface. The central cone and mid-peripheral regions of the keratoconic cornea were evaluated using light microscopy (LM) and larger anatomical and pathological structures were quantified with the aid of NIH image software. Results: The normal cornea contained 242+4 lamellae, while the keratoconic cornea averaged 319+105 but, if an extremely thinned keratoconic cornea was excluded, the average was 360+22. In the keratoconic cornea, the middle and, to a degree, posterior lamellae had broken up into smaller units. In the normal cornea, the ALL and stromal layers showed some shallow overlapping of <1µm in either direction. The anterior stromal lamellae were delicate and interweaved extensively. In central and peripheral LM assessments of the keratoconic cornea, the ALL was thinned or lost over 60% of the area examined and the thin anterior lamellae were absent. Anterior lamellae in central control cornea appeared, at intervals, to terminate surrounded by dense staining particles. This unreported stromal feature was termed electron dense formation and was not observed in the keratoconic cornea. The epithelial thickness varied greatly across the keratoconic cornea (14-92µm), while the epithelium in normal maintained a uniform thickness. Keratoconic specimens contained densely stained, distorted epithelial cells and in 58%, a grossly thickened basement membrane. Stroma in the normal cornea contained predominantly one cell type, the keratocyte, along with the occasional Schwann cell and neuron, but in keratoconus, other cells were present in areas where apparent stromal and ALL disassembling occurred. Conclusions: The keratoconic stroma had paradoxically 50% more lamellae than the normal and this was explained by the fragmentation of lamellae – not an actual increase in lamellae, but… Advisors/Committee Members: Bergmanson, Jan P. (advisor), Goosey, John D. (committee member), Leach, Norman E. (committee member), Miller, William L. (committee member), Twa, Michael D. (committee member), Rabinowitz, Yaron S. (committee member).

Subjects/Keywords: Keratoconus; Human cornea; Histopathology; Keratoconus; Eye – Histopathology

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APA (6^th Edition):

Mathew, J. 1. (2010). MORPHOMETRIC HISTOPATHOLOGY OF THE PHYSIOLOGICALLY FIXED KERATOCONIC CORNEA. (Doctoral Dissertation). University of Houston. Retrieved from http://hdl.handle.net/10657/424

Chicago Manual of Style (16^th Edition):

Mathew, Jessica 1978-. “MORPHOMETRIC HISTOPATHOLOGY OF THE PHYSIOLOGICALLY FIXED KERATOCONIC CORNEA.” 2010. Doctoral Dissertation, University of Houston. Accessed April 18, 2021. http://hdl.handle.net/10657/424.

MLA Handbook (7^th Edition):

Mathew, Jessica 1978-. “MORPHOMETRIC HISTOPATHOLOGY OF THE PHYSIOLOGICALLY FIXED KERATOCONIC CORNEA.” 2010. Web. 18 Apr 2021.

Vancouver:

Mathew J1. MORPHOMETRIC HISTOPATHOLOGY OF THE PHYSIOLOGICALLY FIXED KERATOCONIC CORNEA. [Internet] [Doctoral dissertation]. University of Houston; 2010. [cited 2021 Apr 18]. Available from: http://hdl.handle.net/10657/424.

Council of Science Editors:

Mathew J1. MORPHOMETRIC HISTOPATHOLOGY OF THE PHYSIOLOGICALLY FIXED KERATOCONIC CORNEA. [Doctoral Dissertation]. University of Houston; 2010. Available from: http://hdl.handle.net/10657/424

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Open Access Theses and Dissertations