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You searched for subject:(High throughput screening Drug development ). Showing records 1 – 30 of 100168 total matches.

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University of Aberdeen

1. Mavridis, Lazaros. High throughput virtual drug screening using spherical harmonic molecular surface representations.

Degree: 2009, University of Aberdeen

 This thesis presents new spherical harmonic (SH) approaches for ligand-based high-throughput virtual screening (HTVS). If it is assumed that small drug molecules may be adequately… (more)

Subjects/Keywords: 615; Drugs : High throughput screening (Drug development)

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APA (6th Edition):

Mavridis, L. (2009). High throughput virtual drug screening using spherical harmonic molecular surface representations. (Doctoral Dissertation). University of Aberdeen. Retrieved from http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=25936 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.499650

Chicago Manual of Style (16th Edition):

Mavridis, Lazaros. “High throughput virtual drug screening using spherical harmonic molecular surface representations.” 2009. Doctoral Dissertation, University of Aberdeen. Accessed October 21, 2019. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=25936 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.499650.

MLA Handbook (7th Edition):

Mavridis, Lazaros. “High throughput virtual drug screening using spherical harmonic molecular surface representations.” 2009. Web. 21 Oct 2019.

Vancouver:

Mavridis L. High throughput virtual drug screening using spherical harmonic molecular surface representations. [Internet] [Doctoral dissertation]. University of Aberdeen; 2009. [cited 2019 Oct 21]. Available from: http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=25936 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.499650.

Council of Science Editors:

Mavridis L. High throughput virtual drug screening using spherical harmonic molecular surface representations. [Doctoral Dissertation]. University of Aberdeen; 2009. Available from: http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=25936 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.499650


Oregon State University

2. Mandrell, David. Automated manipulation of zebrafish embryos for high-throughput toxicology screening of nanomaterials.

Degree: MS, Industrial Engineering, 2010, Oregon State University

 The field of nanotechnology has been rapidly developing new materials. These materials have become incorporated into consumer products and the environment after only minimal assessment… (more)

Subjects/Keywords: Automation; High throughput screening (Drug development)

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APA (6th Edition):

Mandrell, D. (2010). Automated manipulation of zebrafish embryos for high-throughput toxicology screening of nanomaterials. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/16495

Chicago Manual of Style (16th Edition):

Mandrell, David. “Automated manipulation of zebrafish embryos for high-throughput toxicology screening of nanomaterials.” 2010. Masters Thesis, Oregon State University. Accessed October 21, 2019. http://hdl.handle.net/1957/16495.

MLA Handbook (7th Edition):

Mandrell, David. “Automated manipulation of zebrafish embryos for high-throughput toxicology screening of nanomaterials.” 2010. Web. 21 Oct 2019.

Vancouver:

Mandrell D. Automated manipulation of zebrafish embryos for high-throughput toxicology screening of nanomaterials. [Internet] [Masters thesis]. Oregon State University; 2010. [cited 2019 Oct 21]. Available from: http://hdl.handle.net/1957/16495.

Council of Science Editors:

Mandrell D. Automated manipulation of zebrafish embryos for high-throughput toxicology screening of nanomaterials. [Masters Thesis]. Oregon State University; 2010. Available from: http://hdl.handle.net/1957/16495


Texas A&M University

3. LaiHing, Steven 1983-. Using High Throughput Screening to Acquire Promising Drug Candidates Against Mycobacterium tuberculosis.

Degree: 2011, Texas A&M University

 Mycobacterium tuberculosis currently affects 1/3 of the world's population. Over the past 20 years tuberculosis has become more resistant to all front line drugs used… (more)

Subjects/Keywords: HTS; TB; MTB; Drug Development and Design; High Throughput Screening; Tuberculosis

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APA (6th Edition):

LaiHing, S. 1. (2011). Using High Throughput Screening to Acquire Promising Drug Candidates Against Mycobacterium tuberculosis. (Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/153195

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

LaiHing, Steven 1983-. “Using High Throughput Screening to Acquire Promising Drug Candidates Against Mycobacterium tuberculosis.” 2011. Thesis, Texas A&M University. Accessed October 21, 2019. http://hdl.handle.net/1969.1/153195.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

LaiHing, Steven 1983-. “Using High Throughput Screening to Acquire Promising Drug Candidates Against Mycobacterium tuberculosis.” 2011. Web. 21 Oct 2019.

Vancouver:

LaiHing S1. Using High Throughput Screening to Acquire Promising Drug Candidates Against Mycobacterium tuberculosis. [Internet] [Thesis]. Texas A&M University; 2011. [cited 2019 Oct 21]. Available from: http://hdl.handle.net/1969.1/153195.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

LaiHing S1. Using High Throughput Screening to Acquire Promising Drug Candidates Against Mycobacterium tuberculosis. [Thesis]. Texas A&M University; 2011. Available from: http://hdl.handle.net/1969.1/153195

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Columbia University

4. Yozwiak, Carrie Elizabeth. Development of Methods for the Discovery of Small Molecule Biological Probes.

Degree: 2017, Columbia University

 Advances in combinatorial chemistry have facilitated the production of large chemical libraries that can be used as tools to discover biological probes and therapeutics. High-throughput(more)

Subjects/Keywords: Chemistry; Biology; Molecular probes; High throughput screening (Drug development)

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APA (6th Edition):

Yozwiak, C. E. (2017). Development of Methods for the Discovery of Small Molecule Biological Probes. (Doctoral Dissertation). Columbia University. Retrieved from https://doi.org/10.7916/D8NZ8KW9

Chicago Manual of Style (16th Edition):

Yozwiak, Carrie Elizabeth. “Development of Methods for the Discovery of Small Molecule Biological Probes.” 2017. Doctoral Dissertation, Columbia University. Accessed October 21, 2019. https://doi.org/10.7916/D8NZ8KW9.

MLA Handbook (7th Edition):

Yozwiak, Carrie Elizabeth. “Development of Methods for the Discovery of Small Molecule Biological Probes.” 2017. Web. 21 Oct 2019.

Vancouver:

Yozwiak CE. Development of Methods for the Discovery of Small Molecule Biological Probes. [Internet] [Doctoral dissertation]. Columbia University; 2017. [cited 2019 Oct 21]. Available from: https://doi.org/10.7916/D8NZ8KW9.

Council of Science Editors:

Yozwiak CE. Development of Methods for the Discovery of Small Molecule Biological Probes. [Doctoral Dissertation]. Columbia University; 2017. Available from: https://doi.org/10.7916/D8NZ8KW9


Rutgers University

5. Inoyama, Daigo, 1981-. The discovery of small-molecule inhibitors of keap1-nrf2 interaction with homogeneous fluorescence-based high throughput screening assays.

Degree: PhD, Medicinal Chemistry, 2014, Rutgers University

Keap1-Nrf2 interaction is a key protein-protein interaction involved in the activation of antioxidant response element which regulates the expression of cytoprotective enzymes in response to… (more)

Subjects/Keywords: Protein-protein interactions; High throughput screening (Drug development)

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APA (6th Edition):

Inoyama, Daigo, 1. (2014). The discovery of small-molecule inhibitors of keap1-nrf2 interaction with homogeneous fluorescence-based high throughput screening assays. (Doctoral Dissertation). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/45302/

Chicago Manual of Style (16th Edition):

Inoyama, Daigo, 1981-. “The discovery of small-molecule inhibitors of keap1-nrf2 interaction with homogeneous fluorescence-based high throughput screening assays.” 2014. Doctoral Dissertation, Rutgers University. Accessed October 21, 2019. https://rucore.libraries.rutgers.edu/rutgers-lib/45302/.

MLA Handbook (7th Edition):

Inoyama, Daigo, 1981-. “The discovery of small-molecule inhibitors of keap1-nrf2 interaction with homogeneous fluorescence-based high throughput screening assays.” 2014. Web. 21 Oct 2019.

Vancouver:

Inoyama, Daigo 1. The discovery of small-molecule inhibitors of keap1-nrf2 interaction with homogeneous fluorescence-based high throughput screening assays. [Internet] [Doctoral dissertation]. Rutgers University; 2014. [cited 2019 Oct 21]. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/45302/.

Council of Science Editors:

Inoyama, Daigo 1. The discovery of small-molecule inhibitors of keap1-nrf2 interaction with homogeneous fluorescence-based high throughput screening assays. [Doctoral Dissertation]. Rutgers University; 2014. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/45302/


University of Hong Kong

6. Tang, Hin-long. High throughput spinning-disk imaging bioassay : from single-cell imaging to whole slide histopathology.

Degree: PhD, 2017, University of Hong Kong

 Accessing detailed spatial information of cells, microscopy allows high-content cell-based phenotypic assay, but at a compromised measurement throughput. Notable example is imaging flow cytometry in… (more)

Subjects/Keywords: Imaging systems in biology; High throughput screening (Drug development); Imaging systems in medicine

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APA (6th Edition):

Tang, H. (2017). High throughput spinning-disk imaging bioassay : from single-cell imaging to whole slide histopathology. (Doctoral Dissertation). University of Hong Kong. Retrieved from http://hdl.handle.net/10722/250756

Chicago Manual of Style (16th Edition):

Tang, Hin-long. “High throughput spinning-disk imaging bioassay : from single-cell imaging to whole slide histopathology.” 2017. Doctoral Dissertation, University of Hong Kong. Accessed October 21, 2019. http://hdl.handle.net/10722/250756.

MLA Handbook (7th Edition):

Tang, Hin-long. “High throughput spinning-disk imaging bioassay : from single-cell imaging to whole slide histopathology.” 2017. Web. 21 Oct 2019.

Vancouver:

Tang H. High throughput spinning-disk imaging bioassay : from single-cell imaging to whole slide histopathology. [Internet] [Doctoral dissertation]. University of Hong Kong; 2017. [cited 2019 Oct 21]. Available from: http://hdl.handle.net/10722/250756.

Council of Science Editors:

Tang H. High throughput spinning-disk imaging bioassay : from single-cell imaging to whole slide histopathology. [Doctoral Dissertation]. University of Hong Kong; 2017. Available from: http://hdl.handle.net/10722/250756


University of Aberdeen

7. Mavridis, Lazaros. High throughput virtual drug screening using spherical harmonic molecular surface representations.

Degree: Dept. of Computing Science., 2009, University of Aberdeen

Subjects/Keywords: Drugs; High throughput screening (Drug development)

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APA (6th Edition):

Mavridis, L. (2009). High throughput virtual drug screening using spherical harmonic molecular surface representations. (Doctoral Dissertation). University of Aberdeen. Retrieved from http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=25936 ; http://digitool2.abdn.ac.uk:1801/webclient/DeliveryManager?pid=25936&custom_att_2=simple_viewer

Chicago Manual of Style (16th Edition):

Mavridis, Lazaros. “High throughput virtual drug screening using spherical harmonic molecular surface representations.” 2009. Doctoral Dissertation, University of Aberdeen. Accessed October 21, 2019. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=25936 ; http://digitool2.abdn.ac.uk:1801/webclient/DeliveryManager?pid=25936&custom_att_2=simple_viewer.

MLA Handbook (7th Edition):

Mavridis, Lazaros. “High throughput virtual drug screening using spherical harmonic molecular surface representations.” 2009. Web. 21 Oct 2019.

Vancouver:

Mavridis L. High throughput virtual drug screening using spherical harmonic molecular surface representations. [Internet] [Doctoral dissertation]. University of Aberdeen; 2009. [cited 2019 Oct 21]. Available from: http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=25936 ; http://digitool2.abdn.ac.uk:1801/webclient/DeliveryManager?pid=25936&custom_att_2=simple_viewer.

Council of Science Editors:

Mavridis L. High throughput virtual drug screening using spherical harmonic molecular surface representations. [Doctoral Dissertation]. University of Aberdeen; 2009. Available from: http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=25936 ; http://digitool2.abdn.ac.uk:1801/webclient/DeliveryManager?pid=25936&custom_att_2=simple_viewer


Columbia University

8. Ray, Forest. PLATE-Seq: An Efficient and Scalable Method for Using RNA-Seq as a Primary Output in High Throughput Drug Screens.

Degree: 2016, Columbia University

 The identification of drug treatments that are useful in diverse therapeutic settings is a significant driving force in biomedical research [Macarron et al., 2011], [Poureetezadi… (more)

Subjects/Keywords: Drugs – Effectiveness; High throughput screening (Drug development); Gene expression – Research – Methodology; Biology

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APA (6th Edition):

Ray, F. (2016). PLATE-Seq: An Efficient and Scalable Method for Using RNA-Seq as a Primary Output in High Throughput Drug Screens. (Doctoral Dissertation). Columbia University. Retrieved from https://doi.org/10.7916/D8DV1K17

Chicago Manual of Style (16th Edition):

Ray, Forest. “PLATE-Seq: An Efficient and Scalable Method for Using RNA-Seq as a Primary Output in High Throughput Drug Screens.” 2016. Doctoral Dissertation, Columbia University. Accessed October 21, 2019. https://doi.org/10.7916/D8DV1K17.

MLA Handbook (7th Edition):

Ray, Forest. “PLATE-Seq: An Efficient and Scalable Method for Using RNA-Seq as a Primary Output in High Throughput Drug Screens.” 2016. Web. 21 Oct 2019.

Vancouver:

Ray F. PLATE-Seq: An Efficient and Scalable Method for Using RNA-Seq as a Primary Output in High Throughput Drug Screens. [Internet] [Doctoral dissertation]. Columbia University; 2016. [cited 2019 Oct 21]. Available from: https://doi.org/10.7916/D8DV1K17.

Council of Science Editors:

Ray F. PLATE-Seq: An Efficient and Scalable Method for Using RNA-Seq as a Primary Output in High Throughput Drug Screens. [Doctoral Dissertation]. Columbia University; 2016. Available from: https://doi.org/10.7916/D8DV1K17


University of Minnesota

9. Liang, Shuang. Identification of compounds inhibiting a Leishmania RNA editing reaction.

Degree: PhD, Pharmacology, 2010, University of Minnesota

 Several species of Leishmania are human pathogens that afflict more than 12 million people worldwide, and the current treatment options are limited. An RNA editing… (more)

Subjects/Keywords: Assay development; Drug identification; High-throughput screening; Leishmania; RNA editing; SELEX; Pharmacology

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APA (6th Edition):

Liang, S. (2010). Identification of compounds inhibiting a Leishmania RNA editing reaction. (Doctoral Dissertation). University of Minnesota. Retrieved from http://purl.umn.edu/100401

Chicago Manual of Style (16th Edition):

Liang, Shuang. “Identification of compounds inhibiting a Leishmania RNA editing reaction.” 2010. Doctoral Dissertation, University of Minnesota. Accessed October 21, 2019. http://purl.umn.edu/100401.

MLA Handbook (7th Edition):

Liang, Shuang. “Identification of compounds inhibiting a Leishmania RNA editing reaction.” 2010. Web. 21 Oct 2019.

Vancouver:

Liang S. Identification of compounds inhibiting a Leishmania RNA editing reaction. [Internet] [Doctoral dissertation]. University of Minnesota; 2010. [cited 2019 Oct 21]. Available from: http://purl.umn.edu/100401.

Council of Science Editors:

Liang S. Identification of compounds inhibiting a Leishmania RNA editing reaction. [Doctoral Dissertation]. University of Minnesota; 2010. Available from: http://purl.umn.edu/100401

10. Kenney, Shelby R. Development of a high throughput small molecule screen using Staphylococcus aureus invasion of cells.

Degree: Thesis (M.S.), 2009, Ball State University

 Staphylococcus aureus is a common and versatile opportunistic pathogen in humans. Increases in the incidence of community acquired and nosocomial infections, coupled with the emergence… (more)

Subjects/Keywords: High throughput screening (Drug development); Staphylococcus aureus; Statins (Cardiovascular agents) – Physiological effect; Endocytosis

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APA (6th Edition):

Kenney, S. R. (2009). Development of a high throughput small molecule screen using Staphylococcus aureus invasion of cells. (Masters Thesis). Ball State University. Retrieved from http://cardinalscholar.bsu.edu/handle/123456789/193789

Chicago Manual of Style (16th Edition):

Kenney, Shelby R. “Development of a high throughput small molecule screen using Staphylococcus aureus invasion of cells.” 2009. Masters Thesis, Ball State University. Accessed October 21, 2019. http://cardinalscholar.bsu.edu/handle/123456789/193789.

MLA Handbook (7th Edition):

Kenney, Shelby R. “Development of a high throughput small molecule screen using Staphylococcus aureus invasion of cells.” 2009. Web. 21 Oct 2019.

Vancouver:

Kenney SR. Development of a high throughput small molecule screen using Staphylococcus aureus invasion of cells. [Internet] [Masters thesis]. Ball State University; 2009. [cited 2019 Oct 21]. Available from: http://cardinalscholar.bsu.edu/handle/123456789/193789.

Council of Science Editors:

Kenney SR. Development of a high throughput small molecule screen using Staphylococcus aureus invasion of cells. [Masters Thesis]. Ball State University; 2009. Available from: http://cardinalscholar.bsu.edu/handle/123456789/193789


IUPUI

11. Bapat, Aditi Ajit. Inhibition of Ape1's DNA Repair Activity as a Target in Cancer: Identification of Novel Small Molecules that have Translational Potential for Molecularly Targeted Cancer Therapy.

Degree: 2010, IUPUI

Indiana University-Purdue University Indianapolis (IUPUI)

The DNA Base Excision Repair (BER) pathway repairs DNA damaged by endogenous and exogenous agents including chemotherapeutic agents. Removal of… (more)

Subjects/Keywords: Ape1; High-throughput screening; Cancer Chemotherapy; Base Excision Repair; DNA Repair; Endonucleases; DNA repair; High throughput screening (Drug development); Cancer  – Prognosis; Cancer  – Chemotherapy

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APA (6th Edition):

Bapat, A. A. (2010). Inhibition of Ape1's DNA Repair Activity as a Target in Cancer: Identification of Novel Small Molecules that have Translational Potential for Molecularly Targeted Cancer Therapy. (Thesis). IUPUI. Retrieved from http://hdl.handle.net/1805/2062

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Bapat, Aditi Ajit. “Inhibition of Ape1's DNA Repair Activity as a Target in Cancer: Identification of Novel Small Molecules that have Translational Potential for Molecularly Targeted Cancer Therapy.” 2010. Thesis, IUPUI. Accessed October 21, 2019. http://hdl.handle.net/1805/2062.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Bapat, Aditi Ajit. “Inhibition of Ape1's DNA Repair Activity as a Target in Cancer: Identification of Novel Small Molecules that have Translational Potential for Molecularly Targeted Cancer Therapy.” 2010. Web. 21 Oct 2019.

Vancouver:

Bapat AA. Inhibition of Ape1's DNA Repair Activity as a Target in Cancer: Identification of Novel Small Molecules that have Translational Potential for Molecularly Targeted Cancer Therapy. [Internet] [Thesis]. IUPUI; 2010. [cited 2019 Oct 21]. Available from: http://hdl.handle.net/1805/2062.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bapat AA. Inhibition of Ape1's DNA Repair Activity as a Target in Cancer: Identification of Novel Small Molecules that have Translational Potential for Molecularly Targeted Cancer Therapy. [Thesis]. IUPUI; 2010. Available from: http://hdl.handle.net/1805/2062

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Hong Kong University of Science and Technology

12. Tian, Honglei. A high throughput screening method for anti-cancer drug leads discovery from the herbal medicine.

Degree: 2006, Hong Kong University of Science and Technology

 A high throughput anti-cancer drug leads screening method has been successfully established employing the cell line we reported in 2001. The method is based on… (more)

Subjects/Keywords: High throughput screening (Drug development); Herbs  – Therapeutic use

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APA (6th Edition):

Tian, H. (2006). A high throughput screening method for anti-cancer drug leads discovery from the herbal medicine. (Thesis). Hong Kong University of Science and Technology. Retrieved from https://doi.org/10.14711/thesis-b930889 ; http://repository.ust.hk/ir/bitstream/1783.1-3798/1/th_redirect.html

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Tian, Honglei. “A high throughput screening method for anti-cancer drug leads discovery from the herbal medicine.” 2006. Thesis, Hong Kong University of Science and Technology. Accessed October 21, 2019. https://doi.org/10.14711/thesis-b930889 ; http://repository.ust.hk/ir/bitstream/1783.1-3798/1/th_redirect.html.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Tian, Honglei. “A high throughput screening method for anti-cancer drug leads discovery from the herbal medicine.” 2006. Web. 21 Oct 2019.

Vancouver:

Tian H. A high throughput screening method for anti-cancer drug leads discovery from the herbal medicine. [Internet] [Thesis]. Hong Kong University of Science and Technology; 2006. [cited 2019 Oct 21]. Available from: https://doi.org/10.14711/thesis-b930889 ; http://repository.ust.hk/ir/bitstream/1783.1-3798/1/th_redirect.html.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Tian H. A high throughput screening method for anti-cancer drug leads discovery from the herbal medicine. [Thesis]. Hong Kong University of Science and Technology; 2006. Available from: https://doi.org/10.14711/thesis-b930889 ; http://repository.ust.hk/ir/bitstream/1783.1-3798/1/th_redirect.html

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of California – Santa Cruz

13. Woehrmann, Marcos H. Predicting the Mode of Action of Bioactive Compounds via High Throughput Screening and Computational Algorithms.

Degree: Biomolecular Engineering and Bioinformatics, 2015, University of California – Santa Cruz

 To develop more effective therapies to treat human diseases, a better method of finding the biological targets and modes of action of new compounds is… (more)

Subjects/Keywords: Bioinformatics; Bioinformatics; Cytological Profiling; Drug Target Prediction; High-throughput Screening; HTS

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APA (6th Edition):

Woehrmann, M. H. (2015). Predicting the Mode of Action of Bioactive Compounds via High Throughput Screening and Computational Algorithms. (Thesis). University of California – Santa Cruz. Retrieved from http://www.escholarship.org/uc/item/9976p4ch

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Woehrmann, Marcos H. “Predicting the Mode of Action of Bioactive Compounds via High Throughput Screening and Computational Algorithms.” 2015. Thesis, University of California – Santa Cruz. Accessed October 21, 2019. http://www.escholarship.org/uc/item/9976p4ch.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Woehrmann, Marcos H. “Predicting the Mode of Action of Bioactive Compounds via High Throughput Screening and Computational Algorithms.” 2015. Web. 21 Oct 2019.

Vancouver:

Woehrmann MH. Predicting the Mode of Action of Bioactive Compounds via High Throughput Screening and Computational Algorithms. [Internet] [Thesis]. University of California – Santa Cruz; 2015. [cited 2019 Oct 21]. Available from: http://www.escholarship.org/uc/item/9976p4ch.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Woehrmann MH. Predicting the Mode of Action of Bioactive Compounds via High Throughput Screening and Computational Algorithms. [Thesis]. University of California – Santa Cruz; 2015. Available from: http://www.escholarship.org/uc/item/9976p4ch

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Vanderbilt University

14. Sandlin, Rebecca Davis. Hemozoin: A Target-Based Approach to Antimalarial Drug Discovery.

Degree: PhD, Chemistry, 2013, Vanderbilt University

 The emergence of drug resistant strains of Plasmodium spp. creates a critical need for the development of novel antimalarials. Hemozoin, a crystalline heme detoxification biomineral… (more)

Subjects/Keywords: beta-hematin; P. falciparum; high-throughput screening; drug discovery; malaria; hemozoin

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APA (6th Edition):

Sandlin, R. D. (2013). Hemozoin: A Target-Based Approach to Antimalarial Drug Discovery. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://etd.library.vanderbilt.edu/available/etd-02252013-071515/ ;

Chicago Manual of Style (16th Edition):

Sandlin, Rebecca Davis. “Hemozoin: A Target-Based Approach to Antimalarial Drug Discovery.” 2013. Doctoral Dissertation, Vanderbilt University. Accessed October 21, 2019. http://etd.library.vanderbilt.edu/available/etd-02252013-071515/ ;.

MLA Handbook (7th Edition):

Sandlin, Rebecca Davis. “Hemozoin: A Target-Based Approach to Antimalarial Drug Discovery.” 2013. Web. 21 Oct 2019.

Vancouver:

Sandlin RD. Hemozoin: A Target-Based Approach to Antimalarial Drug Discovery. [Internet] [Doctoral dissertation]. Vanderbilt University; 2013. [cited 2019 Oct 21]. Available from: http://etd.library.vanderbilt.edu/available/etd-02252013-071515/ ;.

Council of Science Editors:

Sandlin RD. Hemozoin: A Target-Based Approach to Antimalarial Drug Discovery. [Doctoral Dissertation]. Vanderbilt University; 2013. Available from: http://etd.library.vanderbilt.edu/available/etd-02252013-071515/ ;


Northeastern University

15. Silva, Lisseth E. Hit-to-lead optimization of kinase-targeted inhibitors of Trypanosoma brucei growth.

Degree: MS, Department of Chemistry and Chemical Biology, 2016, Northeastern University

 Neglected tropical diseases affect over one billion people worldwide. They are "neglected" because they affect the poorest parts of the world and do not attract… (more)

Subjects/Keywords: high throughput screening; human african trypanosomiasis; neglected tropical diseases; sleeping sickness; target repurposing; Protein kinases; Inhibitors; Therapeutic use; Enzyme inhibitors; Therapeutic use; Trypanosoma brucei; African trypanosomiasis; Treatment; Antiparasitic agents; High throughput screening (Drug development); Drug development

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Silva, L. E. (2016). Hit-to-lead optimization of kinase-targeted inhibitors of Trypanosoma brucei growth. (Masters Thesis). Northeastern University. Retrieved from http://hdl.handle.net/2047/D20195406

Chicago Manual of Style (16th Edition):

Silva, Lisseth E. “Hit-to-lead optimization of kinase-targeted inhibitors of Trypanosoma brucei growth.” 2016. Masters Thesis, Northeastern University. Accessed October 21, 2019. http://hdl.handle.net/2047/D20195406.

MLA Handbook (7th Edition):

Silva, Lisseth E. “Hit-to-lead optimization of kinase-targeted inhibitors of Trypanosoma brucei growth.” 2016. Web. 21 Oct 2019.

Vancouver:

Silva LE. Hit-to-lead optimization of kinase-targeted inhibitors of Trypanosoma brucei growth. [Internet] [Masters thesis]. Northeastern University; 2016. [cited 2019 Oct 21]. Available from: http://hdl.handle.net/2047/D20195406.

Council of Science Editors:

Silva LE. Hit-to-lead optimization of kinase-targeted inhibitors of Trypanosoma brucei growth. [Masters Thesis]. Northeastern University; 2016. Available from: http://hdl.handle.net/2047/D20195406


University of Toronto

16. Chebotarev, Oleg. High Throughput Microfluidic Platform Capable of Mimicking Key Vascular Microenvironments.

Degree: 2013, University of Toronto

The process of finding a new drug against a chosen target for a vascular disease usually involves high-throughput screening in static multi-well plates. However, due… (more)

Subjects/Keywords: Microfluidics; High throughput screening; Drug Screening; Monocyte adhesion; TNF-alpha; 0548; 0541

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APA (6th Edition):

Chebotarev, O. (2013). High Throughput Microfluidic Platform Capable of Mimicking Key Vascular Microenvironments. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/69980

Chicago Manual of Style (16th Edition):

Chebotarev, Oleg. “High Throughput Microfluidic Platform Capable of Mimicking Key Vascular Microenvironments.” 2013. Masters Thesis, University of Toronto. Accessed October 21, 2019. http://hdl.handle.net/1807/69980.

MLA Handbook (7th Edition):

Chebotarev, Oleg. “High Throughput Microfluidic Platform Capable of Mimicking Key Vascular Microenvironments.” 2013. Web. 21 Oct 2019.

Vancouver:

Chebotarev O. High Throughput Microfluidic Platform Capable of Mimicking Key Vascular Microenvironments. [Internet] [Masters thesis]. University of Toronto; 2013. [cited 2019 Oct 21]. Available from: http://hdl.handle.net/1807/69980.

Council of Science Editors:

Chebotarev O. High Throughput Microfluidic Platform Capable of Mimicking Key Vascular Microenvironments. [Masters Thesis]. University of Toronto; 2013. Available from: http://hdl.handle.net/1807/69980


University of New Mexico

17. Saunders, Matthew. Microsphere based protease assays and high throughput screening of bacterial toxin proteases.

Degree: Biomedical Sciences Graduate Program, 2009, University of New Mexico

 Proteases, proteins which cleave peptide bonds in other proteins, are a large and varied group of proteins which regulate a variety of physiological processes. Methodologies… (more)

Subjects/Keywords: High Throughput Screening; Flow Cytometry

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APA (6th Edition):

Saunders, M. (2009). Microsphere based protease assays and high throughput screening of bacterial toxin proteases. (Doctoral Dissertation). University of New Mexico. Retrieved from https://digitalrepository.unm.edu/biom_etds/1

Chicago Manual of Style (16th Edition):

Saunders, Matthew. “Microsphere based protease assays and high throughput screening of bacterial toxin proteases.” 2009. Doctoral Dissertation, University of New Mexico. Accessed October 21, 2019. https://digitalrepository.unm.edu/biom_etds/1.

MLA Handbook (7th Edition):

Saunders, Matthew. “Microsphere based protease assays and high throughput screening of bacterial toxin proteases.” 2009. Web. 21 Oct 2019.

Vancouver:

Saunders M. Microsphere based protease assays and high throughput screening of bacterial toxin proteases. [Internet] [Doctoral dissertation]. University of New Mexico; 2009. [cited 2019 Oct 21]. Available from: https://digitalrepository.unm.edu/biom_etds/1.

Council of Science Editors:

Saunders M. Microsphere based protease assays and high throughput screening of bacterial toxin proteases. [Doctoral Dissertation]. University of New Mexico; 2009. Available from: https://digitalrepository.unm.edu/biom_etds/1


The Ohio State University

18. Zhang, Xudong. 3-D cell-based high-throughput screening for drug discovery and cell culture process development.

Degree: PhD, Ohio State Biochemistry Program, 2008, The Ohio State University

 Based on three-dimensional (3-D) cultures of GFP-expressing mammalian cells, a novel microbiorector array capable of online monitoring of biological activities was developed. The 3-D microbioreactor… (more)

Subjects/Keywords: Biochemistry; Biology; Biomedical Research; Cellular Biology; Chemical Engineering; Pharmaceuticals; Toxicology; 3-D; cell-based; high-throughput screening; drug discovery; cell culture process development; autofluorescence

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APA (6th Edition):

Zhang, X. (2008). 3-D cell-based high-throughput screening for drug discovery and cell culture process development. (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1204701561

Chicago Manual of Style (16th Edition):

Zhang, Xudong. “3-D cell-based high-throughput screening for drug discovery and cell culture process development.” 2008. Doctoral Dissertation, The Ohio State University. Accessed October 21, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1204701561.

MLA Handbook (7th Edition):

Zhang, Xudong. “3-D cell-based high-throughput screening for drug discovery and cell culture process development.” 2008. Web. 21 Oct 2019.

Vancouver:

Zhang X. 3-D cell-based high-throughput screening for drug discovery and cell culture process development. [Internet] [Doctoral dissertation]. The Ohio State University; 2008. [cited 2019 Oct 21]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1204701561.

Council of Science Editors:

Zhang X. 3-D cell-based high-throughput screening for drug discovery and cell culture process development. [Doctoral Dissertation]. The Ohio State University; 2008. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1204701561


The Ohio State University

19. He, Shanshan. Neglected Tropical Disease Chemotherapy: Mechanistic Characterization of Antitrypanosomal Dihydroquinolines and Development of a High Throughput Antileishmanial Screening Assay.

Degree: PhD, Pharmacy, 2012, The Ohio State University

  Human African trypanosomiasis (HAT) and leishmaniasis are identified by the World Health Organization (WHO) as neglected tropical diseases (NTDs), together with Chagas disease and… (more)

Subjects/Keywords: Parasitology; Pharmacy Sciences; Antitrypanosomal dihydroquinolines; Mode of action; Drug-like Properties; High Throughput Antileishmanial Screening

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APA (6th Edition):

He, S. (2012). Neglected Tropical Disease Chemotherapy: Mechanistic Characterization of Antitrypanosomal Dihydroquinolines and Development of a High Throughput Antileishmanial Screening Assay. (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1337980540

Chicago Manual of Style (16th Edition):

He, Shanshan. “Neglected Tropical Disease Chemotherapy: Mechanistic Characterization of Antitrypanosomal Dihydroquinolines and Development of a High Throughput Antileishmanial Screening Assay.” 2012. Doctoral Dissertation, The Ohio State University. Accessed October 21, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1337980540.

MLA Handbook (7th Edition):

He, Shanshan. “Neglected Tropical Disease Chemotherapy: Mechanistic Characterization of Antitrypanosomal Dihydroquinolines and Development of a High Throughput Antileishmanial Screening Assay.” 2012. Web. 21 Oct 2019.

Vancouver:

He S. Neglected Tropical Disease Chemotherapy: Mechanistic Characterization of Antitrypanosomal Dihydroquinolines and Development of a High Throughput Antileishmanial Screening Assay. [Internet] [Doctoral dissertation]. The Ohio State University; 2012. [cited 2019 Oct 21]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1337980540.

Council of Science Editors:

He S. Neglected Tropical Disease Chemotherapy: Mechanistic Characterization of Antitrypanosomal Dihydroquinolines and Development of a High Throughput Antileishmanial Screening Assay. [Doctoral Dissertation]. The Ohio State University; 2012. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1337980540


University of Illinois – Chicago

20. Yapici, Engin. Time-Gated Luminescence Detection for High-Throughput Screening of Protein Interaction and Inhibitions.

Degree: 2015, University of Illinois – Chicago

High throughput screening (HTS) assays are a key component of the drug discovery processes. They are designed to identify biologically active molecules that can ultimately… (more)

Subjects/Keywords: TR-FRET; High-Throughput Screening (HTS); Drug Discovery; Lanthanides; Protein-Protein Interactions (PPI)

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APA (6th Edition):

Yapici, E. (2015). Time-Gated Luminescence Detection for High-Throughput Screening of Protein Interaction and Inhibitions. (Thesis). University of Illinois – Chicago. Retrieved from http://hdl.handle.net/10027/19574

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Yapici, Engin. “Time-Gated Luminescence Detection for High-Throughput Screening of Protein Interaction and Inhibitions.” 2015. Thesis, University of Illinois – Chicago. Accessed October 21, 2019. http://hdl.handle.net/10027/19574.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Yapici, Engin. “Time-Gated Luminescence Detection for High-Throughput Screening of Protein Interaction and Inhibitions.” 2015. Web. 21 Oct 2019.

Vancouver:

Yapici E. Time-Gated Luminescence Detection for High-Throughput Screening of Protein Interaction and Inhibitions. [Internet] [Thesis]. University of Illinois – Chicago; 2015. [cited 2019 Oct 21]. Available from: http://hdl.handle.net/10027/19574.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Yapici E. Time-Gated Luminescence Detection for High-Throughput Screening of Protein Interaction and Inhibitions. [Thesis]. University of Illinois – Chicago; 2015. Available from: http://hdl.handle.net/10027/19574

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Western Ontario

21. Black, Morgan D. High Throughput Screening For Drug Discovery In Head And Neck Squamous Cell Carcinoma.

Degree: 2015, University of Western Ontario

 Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide and despite advancements in traditional therapies, the survival rate of ~40%… (more)

Subjects/Keywords: HNSCC; HPV; high throughput; drug screening; targeted therapy; precision medicine; Translational Medical Research

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APA (6th Edition):

Black, M. D. (2015). High Throughput Screening For Drug Discovery In Head And Neck Squamous Cell Carcinoma. (Thesis). University of Western Ontario. Retrieved from https://ir.lib.uwo.ca/etd/3154

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Black, Morgan D. “High Throughput Screening For Drug Discovery In Head And Neck Squamous Cell Carcinoma.” 2015. Thesis, University of Western Ontario. Accessed October 21, 2019. https://ir.lib.uwo.ca/etd/3154.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Black, Morgan D. “High Throughput Screening For Drug Discovery In Head And Neck Squamous Cell Carcinoma.” 2015. Web. 21 Oct 2019.

Vancouver:

Black MD. High Throughput Screening For Drug Discovery In Head And Neck Squamous Cell Carcinoma. [Internet] [Thesis]. University of Western Ontario; 2015. [cited 2019 Oct 21]. Available from: https://ir.lib.uwo.ca/etd/3154.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Black MD. High Throughput Screening For Drug Discovery In Head And Neck Squamous Cell Carcinoma. [Thesis]. University of Western Ontario; 2015. Available from: https://ir.lib.uwo.ca/etd/3154

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Illinois – Chicago

22. Rice, Amy J. Dihydroorotase from Bacillus anthracis and Staphylococcus aureus.

Degree: 2016, University of Illinois – Chicago

 The de novo pyrimidine biosynthesis pathway is a potential target for antibacterial drug development and has been implicated in bacterial survival and proliferation during host… (more)

Subjects/Keywords: Drug discovery; High-throughput screening; Protein purification; Surface Plasmon Resonance; X-ray crystallography

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APA (6th Edition):

Rice, A. J. (2016). Dihydroorotase from Bacillus anthracis and Staphylococcus aureus. (Thesis). University of Illinois – Chicago. Retrieved from http://hdl.handle.net/10027/21340

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Rice, Amy J. “Dihydroorotase from Bacillus anthracis and Staphylococcus aureus.” 2016. Thesis, University of Illinois – Chicago. Accessed October 21, 2019. http://hdl.handle.net/10027/21340.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Rice, Amy J. “Dihydroorotase from Bacillus anthracis and Staphylococcus aureus.” 2016. Web. 21 Oct 2019.

Vancouver:

Rice AJ. Dihydroorotase from Bacillus anthracis and Staphylococcus aureus. [Internet] [Thesis]. University of Illinois – Chicago; 2016. [cited 2019 Oct 21]. Available from: http://hdl.handle.net/10027/21340.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Rice AJ. Dihydroorotase from Bacillus anthracis and Staphylococcus aureus. [Thesis]. University of Illinois – Chicago; 2016. Available from: http://hdl.handle.net/10027/21340

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Loyola University Chicago

23. Prajapati, Kushal. Development of Cell Based Reporter Assay to Measure PKC-Delta Promoter Activity.

Degree: MS, Pharmacology and Experimental Therapeutics, 2013, Loyola University Chicago

  Protein kinase C- δ (PKC-δ) acts as a tumor suppressor in skin cancer and is lost in 30% of human Squamous Cell Carcinoma (SCC).… (more)

Subjects/Keywords: Drug Discovery; Gene Reporter Assay; High Throughput Screening; PKC-Delta; Pharmacy and Pharmaceutical Sciences

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APA (6th Edition):

Prajapati, K. (2013). Development of Cell Based Reporter Assay to Measure PKC-Delta Promoter Activity. (Thesis). Loyola University Chicago. Retrieved from http://ecommons.luc.edu/luc_theses/1862

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Prajapati, Kushal. “Development of Cell Based Reporter Assay to Measure PKC-Delta Promoter Activity.” 2013. Thesis, Loyola University Chicago. Accessed October 21, 2019. http://ecommons.luc.edu/luc_theses/1862.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Prajapati, Kushal. “Development of Cell Based Reporter Assay to Measure PKC-Delta Promoter Activity.” 2013. Web. 21 Oct 2019.

Vancouver:

Prajapati K. Development of Cell Based Reporter Assay to Measure PKC-Delta Promoter Activity. [Internet] [Thesis]. Loyola University Chicago; 2013. [cited 2019 Oct 21]. Available from: http://ecommons.luc.edu/luc_theses/1862.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Prajapati K. Development of Cell Based Reporter Assay to Measure PKC-Delta Promoter Activity. [Thesis]. Loyola University Chicago; 2013. Available from: http://ecommons.luc.edu/luc_theses/1862

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of New Mexico

24. Zhu, Jingsh. DEVELOPMENT AND KINETIC MODELING OF MULTIPLEX MICROSPHERE ASSAYS FOR HIGH-THROUGHPUT DISCOVERY OF PROTEASE ACTIVE SMALL MOLECULE COMPOUNDS.

Degree: Nanoscience and Microsystems, 2014, University of New Mexico

 In this dissertation, we have designed a series of recombinant fluorescent full-length protease substrates containing the cleavage sites separated by a biotinylation tag and a… (more)

Subjects/Keywords: Protease; Microsphere; Multiplex; High-throughput screening; Drug Discovery; Inhibitors; Kinetic mechanism; Nanosphere

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APA (6th Edition):

Zhu, J. (2014). DEVELOPMENT AND KINETIC MODELING OF MULTIPLEX MICROSPHERE ASSAYS FOR HIGH-THROUGHPUT DISCOVERY OF PROTEASE ACTIVE SMALL MOLECULE COMPOUNDS. (Doctoral Dissertation). University of New Mexico. Retrieved from http://hdl.handle.net/1928/24363

Chicago Manual of Style (16th Edition):

Zhu, Jingsh. “DEVELOPMENT AND KINETIC MODELING OF MULTIPLEX MICROSPHERE ASSAYS FOR HIGH-THROUGHPUT DISCOVERY OF PROTEASE ACTIVE SMALL MOLECULE COMPOUNDS.” 2014. Doctoral Dissertation, University of New Mexico. Accessed October 21, 2019. http://hdl.handle.net/1928/24363.

MLA Handbook (7th Edition):

Zhu, Jingsh. “DEVELOPMENT AND KINETIC MODELING OF MULTIPLEX MICROSPHERE ASSAYS FOR HIGH-THROUGHPUT DISCOVERY OF PROTEASE ACTIVE SMALL MOLECULE COMPOUNDS.” 2014. Web. 21 Oct 2019.

Vancouver:

Zhu J. DEVELOPMENT AND KINETIC MODELING OF MULTIPLEX MICROSPHERE ASSAYS FOR HIGH-THROUGHPUT DISCOVERY OF PROTEASE ACTIVE SMALL MOLECULE COMPOUNDS. [Internet] [Doctoral dissertation]. University of New Mexico; 2014. [cited 2019 Oct 21]. Available from: http://hdl.handle.net/1928/24363.

Council of Science Editors:

Zhu J. DEVELOPMENT AND KINETIC MODELING OF MULTIPLEX MICROSPHERE ASSAYS FOR HIGH-THROUGHPUT DISCOVERY OF PROTEASE ACTIVE SMALL MOLECULE COMPOUNDS. [Doctoral Dissertation]. University of New Mexico; 2014. Available from: http://hdl.handle.net/1928/24363


University of California – San Francisco

25. Liu, Harrison Yi. Development of Tools for Whole-Organism High-Throughput Screening.

Degree: Bioengineering, 2016, University of California – San Francisco

High-throughput screening (HTS) leverages laboratory automation and advanced analytics in order to perform experiments much more quickly than what can be accomplished by hand. Since… (more)

Subjects/Keywords: Biomedical engineering; Health sciences; Pharmaceutical sciences; c. elegans; drug discovery; high-throughput screening; zebrafish

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APA (6th Edition):

Liu, H. Y. (2016). Development of Tools for Whole-Organism High-Throughput Screening. (Thesis). University of California – San Francisco. Retrieved from http://www.escholarship.org/uc/item/8bn862xw

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Liu, Harrison Yi. “Development of Tools for Whole-Organism High-Throughput Screening.” 2016. Thesis, University of California – San Francisco. Accessed October 21, 2019. http://www.escholarship.org/uc/item/8bn862xw.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Liu, Harrison Yi. “Development of Tools for Whole-Organism High-Throughput Screening.” 2016. Web. 21 Oct 2019.

Vancouver:

Liu HY. Development of Tools for Whole-Organism High-Throughput Screening. [Internet] [Thesis]. University of California – San Francisco; 2016. [cited 2019 Oct 21]. Available from: http://www.escholarship.org/uc/item/8bn862xw.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Liu HY. Development of Tools for Whole-Organism High-Throughput Screening. [Thesis]. University of California – San Francisco; 2016. Available from: http://www.escholarship.org/uc/item/8bn862xw

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Minnesota

26. Simpkins, Scott. Analysis and interpretation of high-throughput chemical-genetic interaction screens.

Degree: PhD, Biomedical Informatics and Computational Biology, 2018, University of Minnesota

Screening chemical compounds against genome-wide mutant arrays identifies genetic perturbations that cause sensitivity or resistance to compounds of interest. The resulting chemical-genetic interaction profiles contain… (more)

Subjects/Keywords: chemical-genetic interactions; computational biology; drug discovery; genetic interactions; high-throughput screening; saccharomyces cerevisiae

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APA (6th Edition):

Simpkins, S. (2018). Analysis and interpretation of high-throughput chemical-genetic interaction screens. (Doctoral Dissertation). University of Minnesota. Retrieved from http://hdl.handle.net/11299/206377

Chicago Manual of Style (16th Edition):

Simpkins, Scott. “Analysis and interpretation of high-throughput chemical-genetic interaction screens.” 2018. Doctoral Dissertation, University of Minnesota. Accessed October 21, 2019. http://hdl.handle.net/11299/206377.

MLA Handbook (7th Edition):

Simpkins, Scott. “Analysis and interpretation of high-throughput chemical-genetic interaction screens.” 2018. Web. 21 Oct 2019.

Vancouver:

Simpkins S. Analysis and interpretation of high-throughput chemical-genetic interaction screens. [Internet] [Doctoral dissertation]. University of Minnesota; 2018. [cited 2019 Oct 21]. Available from: http://hdl.handle.net/11299/206377.

Council of Science Editors:

Simpkins S. Analysis and interpretation of high-throughput chemical-genetic interaction screens. [Doctoral Dissertation]. University of Minnesota; 2018. Available from: http://hdl.handle.net/11299/206377


University of Rochester

27. Trombetta, Ryan P. Sustained delivery of antimicrobials from 3D printed calcium phosphate scaffolds in single-stage management of osteomyelitis.

Degree: PhD, 2019, University of Rochester

 Implant-associated osteomyelitis is a bacterial bone infection that is the bane of existence for orthopedic surgeons due to its relapsing nature. The gold standard for… (more)

Subjects/Keywords: 1-stage revision; 3D printing; Drug delivery; High throughput screening; Osteomyelitis; Staphylococcus aureus

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APA (6th Edition):

Trombetta, R. P. (2019). Sustained delivery of antimicrobials from 3D printed calcium phosphate scaffolds in single-stage management of osteomyelitis. (Doctoral Dissertation). University of Rochester. Retrieved from http://hdl.handle.net/1802/35290

Chicago Manual of Style (16th Edition):

Trombetta, Ryan P. “Sustained delivery of antimicrobials from 3D printed calcium phosphate scaffolds in single-stage management of osteomyelitis.” 2019. Doctoral Dissertation, University of Rochester. Accessed October 21, 2019. http://hdl.handle.net/1802/35290.

MLA Handbook (7th Edition):

Trombetta, Ryan P. “Sustained delivery of antimicrobials from 3D printed calcium phosphate scaffolds in single-stage management of osteomyelitis.” 2019. Web. 21 Oct 2019.

Vancouver:

Trombetta RP. Sustained delivery of antimicrobials from 3D printed calcium phosphate scaffolds in single-stage management of osteomyelitis. [Internet] [Doctoral dissertation]. University of Rochester; 2019. [cited 2019 Oct 21]. Available from: http://hdl.handle.net/1802/35290.

Council of Science Editors:

Trombetta RP. Sustained delivery of antimicrobials from 3D printed calcium phosphate scaffolds in single-stage management of osteomyelitis. [Doctoral Dissertation]. University of Rochester; 2019. Available from: http://hdl.handle.net/1802/35290

28. McCallum, Megan Marie. High-Throughput Approaches for the Assessment of Factors Influencing Bioavailability of Small Molecules in Pre-Clinical Drug Development.

Degree: PhD, Chemistry, 2013, University of Wisconsin – Milwaukee

  A bioactive molecule must pass many hurdles to be designated as a "good" pharmaceutical lead or hit compound. It should have a significant activity,… (more)

Subjects/Keywords: Drug Bioavailability; Drug Electrophilicity; Drug Permeability; Drug-Protein Binding; High-Throughput Screening; Pre-Clinical Drug Development; Analytical Chemistry; Biochemistry; Chemistry

…stages. 11 4. Analytical Methods in High-Throughput Screening For the development of new high… …speed in analysis is very important for high-throughput screening.42 Many drug molecules have… …197 xv LIST OF ABBREVIATIONS HTS High-throughput Screening HT High-throughput ADME… …x28;high-throughput screening, HTS).1 With the advent of combinatorial chemistry and… …High-Throughput In Vitro Pre-clinical Assays Understanding the interactions between drug… 

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APA (6th Edition):

McCallum, M. M. (2013). High-Throughput Approaches for the Assessment of Factors Influencing Bioavailability of Small Molecules in Pre-Clinical Drug Development. (Doctoral Dissertation). University of Wisconsin – Milwaukee. Retrieved from https://dc.uwm.edu/etd/139

Chicago Manual of Style (16th Edition):

McCallum, Megan Marie. “High-Throughput Approaches for the Assessment of Factors Influencing Bioavailability of Small Molecules in Pre-Clinical Drug Development.” 2013. Doctoral Dissertation, University of Wisconsin – Milwaukee. Accessed October 21, 2019. https://dc.uwm.edu/etd/139.

MLA Handbook (7th Edition):

McCallum, Megan Marie. “High-Throughput Approaches for the Assessment of Factors Influencing Bioavailability of Small Molecules in Pre-Clinical Drug Development.” 2013. Web. 21 Oct 2019.

Vancouver:

McCallum MM. High-Throughput Approaches for the Assessment of Factors Influencing Bioavailability of Small Molecules in Pre-Clinical Drug Development. [Internet] [Doctoral dissertation]. University of Wisconsin – Milwaukee; 2013. [cited 2019 Oct 21]. Available from: https://dc.uwm.edu/etd/139.

Council of Science Editors:

McCallum MM. High-Throughput Approaches for the Assessment of Factors Influencing Bioavailability of Small Molecules in Pre-Clinical Drug Development. [Doctoral Dissertation]. University of Wisconsin – Milwaukee; 2013. Available from: https://dc.uwm.edu/etd/139


University of California – Irvine

29. Lee, Eugene. Enhanced Detection of Drug-induced Cardiotoxicity in Human Stem Cell-Derived Cardiomyocytes Using Optical Flow, Biomimetic Substrates, and Machine Learning.

Degree: Biomedical Engineering, 2017, University of California – Irvine

 Current preclinical screening methods are ineffective at detecting cardiotoxicity: 30% of drug attritions are attributed to drug-induced cardiotoxicity. With recent advancements in stem cell technologies,… (more)

Subjects/Keywords: Biomedical engineering; Biomimetic Materials; Cardiotoxicity; High-throughput drug screening; Machine Learning; Optical Flow; Stem Cell Derived Cardiomyocytes

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Lee, E. (2017). Enhanced Detection of Drug-induced Cardiotoxicity in Human Stem Cell-Derived Cardiomyocytes Using Optical Flow, Biomimetic Substrates, and Machine Learning. (Thesis). University of California – Irvine. Retrieved from http://www.escholarship.org/uc/item/7zj4h938

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Lee, Eugene. “Enhanced Detection of Drug-induced Cardiotoxicity in Human Stem Cell-Derived Cardiomyocytes Using Optical Flow, Biomimetic Substrates, and Machine Learning.” 2017. Thesis, University of California – Irvine. Accessed October 21, 2019. http://www.escholarship.org/uc/item/7zj4h938.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Lee, Eugene. “Enhanced Detection of Drug-induced Cardiotoxicity in Human Stem Cell-Derived Cardiomyocytes Using Optical Flow, Biomimetic Substrates, and Machine Learning.” 2017. Web. 21 Oct 2019.

Vancouver:

Lee E. Enhanced Detection of Drug-induced Cardiotoxicity in Human Stem Cell-Derived Cardiomyocytes Using Optical Flow, Biomimetic Substrates, and Machine Learning. [Internet] [Thesis]. University of California – Irvine; 2017. [cited 2019 Oct 21]. Available from: http://www.escholarship.org/uc/item/7zj4h938.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Lee E. Enhanced Detection of Drug-induced Cardiotoxicity in Human Stem Cell-Derived Cardiomyocytes Using Optical Flow, Biomimetic Substrates, and Machine Learning. [Thesis]. University of California – Irvine; 2017. Available from: http://www.escholarship.org/uc/item/7zj4h938

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


McMaster University

30. Zlitni, Soumaya. DISCOVERY AND CHARACTERIZATION OF INHIBITORS OF BACTERIAL METABOLISM.

Degree: PhD, 2014, McMaster University

The alarming rise of antibacterial drug resistance and the dwindling supply of novel antibiotics highlight the need for innovative approaches in combating bacterial infections. Traditionally,… (more)

Subjects/Keywords: Antibiotic; Drug discovery; Chemical Biology; Bacteria; Metabolism; Mechanism of action; Small molecule inhibitors; High-throughput screening; Enzymology; Genetics; Bacterial physiology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Zlitni, S. (2014). DISCOVERY AND CHARACTERIZATION OF INHIBITORS OF BACTERIAL METABOLISM. (Doctoral Dissertation). McMaster University. Retrieved from http://hdl.handle.net/11375/15992

Chicago Manual of Style (16th Edition):

Zlitni, Soumaya. “DISCOVERY AND CHARACTERIZATION OF INHIBITORS OF BACTERIAL METABOLISM.” 2014. Doctoral Dissertation, McMaster University. Accessed October 21, 2019. http://hdl.handle.net/11375/15992.

MLA Handbook (7th Edition):

Zlitni, Soumaya. “DISCOVERY AND CHARACTERIZATION OF INHIBITORS OF BACTERIAL METABOLISM.” 2014. Web. 21 Oct 2019.

Vancouver:

Zlitni S. DISCOVERY AND CHARACTERIZATION OF INHIBITORS OF BACTERIAL METABOLISM. [Internet] [Doctoral dissertation]. McMaster University; 2014. [cited 2019 Oct 21]. Available from: http://hdl.handle.net/11375/15992.

Council of Science Editors:

Zlitni S. DISCOVERY AND CHARACTERIZATION OF INHIBITORS OF BACTERIAL METABOLISM. [Doctoral Dissertation]. McMaster University; 2014. Available from: http://hdl.handle.net/11375/15992

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