subject:(Fluido c rebro espinal)

1. Saciloto, Thalita Rocha. Desenvolvimento e aplicação de eletrodos compósitos impressos à base de grafite e poliuretana.

Degree: PhD, Química Analítica e Inorgânica, 2014, University of São Paulo

URL: http://www.teses.usp.br/teses/disponiveis/75/75135/tde-29042015-162546/ ;

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Um método de fabricação para eletrodos compósitos impressos à base de grafite e resina poliuretana (EIGPU) foi desenvolvido, iniciando-se pela tinta e processo para a… (more)

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Um método de fabricação para eletrodos compósitos impressos à base de grafite e resina poliuretana (EIGPU) foi desenvolvido, iniciando-se pela tinta e processo para a impressão, além da otimização dos parâmetros para garantir a aplicabilidade e maximização da resposta dos mesmos. Os parâmetros otimizados na fabricação da tinta foram a composição de 60% grafite e 40% poliuretana (m/m), a natureza e quantidade de solvente, dimensão do conjunto impresso, quantidade de demãos aplicadas no processo de \"screen-printing\", espessura da máscara adesiva e o tipo de isolante que define os contatos elétricos e a área ativa do eletrodo. Também foi proposto e desenvolvido um procedimento de ativação da superfície do eletrodo, que consiste em uma compressão do compósito, seguido de tratamento eletroquímico da superfície do eletrodo de trabalho, que se mostraram fundamentais para o desempenho adequado do sensor. Os resultados desses estudos inciais foram avaliados usando K3[Fe(CN)6], como sonda eletroquímica. Em seguida, o EIGPU foi avaliado quanto ao seu potencial para determinação de analitos de interesse farmacológico, usando como modelo o paracetamola (APAP) e suas misturasb com cafeína (CAF) em amostras de fármacos (LOD=0,81a, 0,84b(APAP), 1,6b(CAF) µmol L-1); ambiental: Zn2+, Pb2+, Cu2+ e Hg2+ simultaneamente em amostras de etanol combustível (LOD=300, 65, 30, 46 nmol L-1, respectivamente) e biológico: epinefrina (EP) em amostras artificiais de fluido cérebro-espinal sintético (LOD=42,8 e 768 nmol L-1, para DPV e SWV, respectivamente). Para isso, foram usadas Voltametria Cíclica (CV), Voltametria de Pulso Diferencial (DPV), Voltametria de Pulso Diferencial de Redissolução Anódica (DPASV) e Voltametria de Onda Quadrada (SWV). Na determinação dos analitos de interesse ambiental, os eletrodos impressos foram modificados com sílica SBA-15, antes e após organofuncionalização com a espécie benzotiazol-2-tiol. Os compósitos modificados foram preparados substituindo quantidades correspondentes de pó de grafite de modo a obter eletrodos com 5% (m/m) do modificador. Antes de realizar as análises, foram feitas as otimizações dos parâmetros envolvidos em cada técnica escolhida e obtidas as curvas analíticas. Em seguida, o EIGPU foi utilizado na determinação dos analitos nas respectivas matrizes. A quantidade dos analitos presentes nas amostras foi determinada pelo método de adição de padrão, em triplicata. Os resultados foram comparados com aqueles obtidos por Cromatografia Líquida de Alta Eficiência (HPLC) e Espectroscopia de Absorção Atômica (AAS), para as análises farmacêuticas e ambientais, respectivamente.

A method for the fabrication of a graphite polyurethane composite based screen printed electrodes (EIGPU) was proposed by developing a ink and a imprinting procedure after optimizing parameters such as ink composition 60% graphite and 40% polyurethane (m/m), nature and quantity of solvent, dimensions of the electrode set, number of ink layers, deepness of the adhesive mask and nature of the insulating that defines the active…

Advisors/Committee Members: Cavalheiro, Eder Tadeu Gomes.

Subjects/Keywords: Amostras farmacêuticas; Cerebro-spinal fluid; Electroanalysis; Eletroanálise; Eletrodo impresso; Etanol combustível; Ethanol fuel; Fluido cérebro-espinal; Pharmaceutical samples; Screen-printed electrode

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Saciloto, T. R. (2014). Desenvolvimento e aplicação de eletrodos compósitos impressos à base de grafite e poliuretana. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/75/75135/tde-29042015-162546/ ;

Chicago Manual of Style (16^th Edition):

Saciloto, Thalita Rocha. “Desenvolvimento e aplicação de eletrodos compósitos impressos à base de grafite e poliuretana.” 2014. Doctoral Dissertation, University of São Paulo. Accessed January 22, 2021. http://www.teses.usp.br/teses/disponiveis/75/75135/tde-29042015-162546/ ;.

MLA Handbook (7^th Edition):

Saciloto, Thalita Rocha. “Desenvolvimento e aplicação de eletrodos compósitos impressos à base de grafite e poliuretana.” 2014. Web. 22 Jan 2021.

Vancouver:

Saciloto TR. Desenvolvimento e aplicação de eletrodos compósitos impressos à base de grafite e poliuretana. [Internet] [Doctoral dissertation]. University of São Paulo; 2014. [cited 2021 Jan 22]. Available from: http://www.teses.usp.br/teses/disponiveis/75/75135/tde-29042015-162546/ ;.

Council of Science Editors:

Saciloto TR. Desenvolvimento e aplicação de eletrodos compósitos impressos à base de grafite e poliuretana. [Doctoral Dissertation]. University of São Paulo; 2014. Available from: http://www.teses.usp.br/teses/disponiveis/75/75135/tde-29042015-162546/ ;

Universidade do Rio Grande do Sul

2. Riffel, Ana Paula Konzen. Vitamina C e vitamina E atenuam a nocicepção e modificam parâmetros oxidativos e proteínas de sinalização em medula espinal de ratos com dor neuropática.

Degree: 2017, Universidade do Rio Grande do Sul

URL: http://hdl.handle.net/10183/175089

► A dor neuropática (dor devido à lesão no tecido nervoso) é uma condição debilitante, com alta incidência na população mundial. O tratamento dessa condição dolorosa… (more)

▼ A dor neuropática (dor devido à lesão no tecido nervoso) é uma condição debilitante, com alta incidência na população mundial. O tratamento dessa condição dolorosa ainda é um grande desafio na clínica devido às ações limitadas dos fármacos atualmente disponíveis e seus consequentes efeitos colaterais. O uso de substâncias com potencial antioxidante no tratamento da dor neuropática vem sendo amplamente discutido devido à participação das espécies reativas de oxigênio e de nitrogênio nessa condição dolorosa. O ácido ascórbico (vitamina C) e o !-tocoferol (vitamina E) representam potentes antioxidantes, os quais são adquiridos por custo relativamente baixo, são bem aceitos pela população, muito utilizados como suplemento alimentar, e parecem possuir algum efeito analgésico, embora esse último efeito tenha ainda muitas questões especulativas e que necessita esclarecimentos. Por estes motivos, o objetivo deste estudo foi avaliar o efeito das vitaminas C e E, administradas isoladas ou juntas, sobre parâmetros nociceptivos, oxidativos e nitrosativos, e proteínas de sinalização intracelular em ratos com constrição no nervo isquiático (CCI, do inglês chronic constriction injury), um modelo de dor neuropática. Após aprovação pelo comitê de ética no uso de animal da UFRGS (#23352), ratos Wistar machos, com idade de 60 dias, foram divididos em 3 grupos experimentais: controle (ratos que não sofreram intervenção cirúrgica), sham (ratos que tiveram o nervo isquiático direito apenas exposto) e CCI (ratos que tiveram o nervo isquiático exposto e esse recebeu 4 amarraduras em seu tronco comum). Cada grupo experimental foi dividido em subgrupos que receberam administração de veículo (salina ou água de beber acrescidas de Tween 80 a 1%), vitamina C (30 mg/kg/dia), vitamina E (15 mg/kg/dia) ou coadministração de vitaminas C+E nas mesmas doses. As administrações foram intraperitoneal ou por via oral, por período de 3 e 10 dias. Os parâmetros nociceptivos utilizados para avaliar sensibilidade mecânica, sensibilidade térmica e recuperação funcional do nervo foram os testes de von Frey eletrônico, teste da placa quente e do índice funcional do isquiático (IFI), respectivamente. Para avaliar o efeito antinociceptivo da administração i.p. dos tratamentos, os parâmetros nociceptivos foram mensurados antes do procedimento cirúrgico, e aos 3, 5, 7 e 10 dias após a lesão nervosa. Ao final dos períodos de 3 e 10 dias, os animais foram mortos por decapitação, e foi coletado plasma, para determinação de indicadores de função hepática e renal (alanina aminotransferase, aspartato aminotransferase, gama GT, bilirrubina e creatinina); fígado, para determinação da morfologia dos hepatócitos e parâmetros oxidativos (hidroperóxidos lipídicos, Glutationa-s-transferase - GST, e capacidade antioxidante total - TAC); nervo isquiático lesionado, para determinação de parâmetros oxidativos (hidroperóxidos lipídicos e TAC); e o segmento lombossacral da medula espinal, para determinação de parâmetros oxidativos (formação de ânion superóxido - SAG, e valores de… Advisors/Committee Members: Partata, Wania Aparecida.

Subjects/Keywords: Ácido ascórbico; Vitamin C; Vitamina E; Oxidative stress; Neuropathic pain; Alfa-tocoferol; Neuralgia; Vitamin E; Nociceptividade; Estresse oxidativo; Medula espinal

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Riffel, A. P. K. (2017). Vitamina C e vitamina E atenuam a nocicepção e modificam parâmetros oxidativos e proteínas de sinalização em medula espinal de ratos com dor neuropática. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/175089

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Riffel, Ana Paula Konzen. “Vitamina C e vitamina E atenuam a nocicepção e modificam parâmetros oxidativos e proteínas de sinalização em medula espinal de ratos com dor neuropática.” 2017. Thesis, Universidade do Rio Grande do Sul. Accessed January 22, 2021. http://hdl.handle.net/10183/175089.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Riffel, Ana Paula Konzen. “Vitamina C e vitamina E atenuam a nocicepção e modificam parâmetros oxidativos e proteínas de sinalização em medula espinal de ratos com dor neuropática.” 2017. Web. 22 Jan 2021.

Vancouver:

Riffel APK. Vitamina C e vitamina E atenuam a nocicepção e modificam parâmetros oxidativos e proteínas de sinalização em medula espinal de ratos com dor neuropática. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2017. [cited 2021 Jan 22]. Available from: http://hdl.handle.net/10183/175089.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Riffel APK. Vitamina C e vitamina E atenuam a nocicepção e modificam parâmetros oxidativos e proteínas de sinalização em medula espinal de ratos com dor neuropática. [Thesis]. Universidade do Rio Grande do Sul; 2017. Available from: http://hdl.handle.net/10183/175089

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Brno University of Technology

3. Figuli, Juraj. Predpätý most cez rieku Oravu: Prestressed bridge over the Orava river.

Degree: 2019, Brno University of Technology

URL: http://hdl.handle.net/11012/29189

► The objective of bachelor’s thesis is design and dimensions of a single pole road bridge, which is designed for traffic in the city. Work forms… (more)

Subjects/Keywords: Predpätie; dvoj-trám; rebro.; Prestress; two-beam; rib.

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APA (6^th Edition):

Figuli, J. (2019). Predpätý most cez rieku Oravu: Prestressed bridge over the Orava river. (Thesis). Brno University of Technology. Retrieved from http://hdl.handle.net/11012/29189

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Figuli, Juraj. “Predpätý most cez rieku Oravu: Prestressed bridge over the Orava river.” 2019. Thesis, Brno University of Technology. Accessed January 22, 2021. http://hdl.handle.net/11012/29189.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Figuli, Juraj. “Predpätý most cez rieku Oravu: Prestressed bridge over the Orava river.” 2019. Web. 22 Jan 2021.

Vancouver:

Figuli J. Predpätý most cez rieku Oravu: Prestressed bridge over the Orava river. [Internet] [Thesis]. Brno University of Technology; 2019. [cited 2021 Jan 22]. Available from: http://hdl.handle.net/11012/29189.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Figuli J. Predpätý most cez rieku Oravu: Prestressed bridge over the Orava river. [Thesis]. Brno University of Technology; 2019. Available from: http://hdl.handle.net/11012/29189

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidad de Valladolid

4. Valsero Herguedas, María Esther. Efecto neurotrófico "in vivo" del fluido cerebroespinal embrionario durante el desarrollo de la médula espinal y en células mesenquimales y amnióticas.

Degree: 2015, Universidad de Valladolid

URL: http://uvadoc.uva.es/handle/10324/17978

► Se ha demostrado la función del fluido cerebroespinal embrionario (E-CSF) como regulador del comportamiento neuroepitelial en mesencéfalo, en embriones de pollo y rata. Factores de… (more)

Subjects/Keywords: Neurología; Embriología; Médula espinal

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Valsero Herguedas, M. E. (2015). Efecto neurotrófico "in vivo" del fluido cerebroespinal embrionario durante el desarrollo de la médula espinal y en células mesenquimales y amnióticas. (Thesis). Universidad de Valladolid. Retrieved from http://uvadoc.uva.es/handle/10324/17978

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Valsero Herguedas, María Esther. “Efecto neurotrófico "in vivo" del fluido cerebroespinal embrionario durante el desarrollo de la médula espinal y en células mesenquimales y amnióticas.” 2015. Thesis, Universidad de Valladolid. Accessed January 22, 2021. http://uvadoc.uva.es/handle/10324/17978.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Valsero Herguedas, María Esther. “Efecto neurotrófico "in vivo" del fluido cerebroespinal embrionario durante el desarrollo de la médula espinal y en células mesenquimales y amnióticas.” 2015. Web. 22 Jan 2021.

Vancouver:

Valsero Herguedas ME. Efecto neurotrófico "in vivo" del fluido cerebroespinal embrionario durante el desarrollo de la médula espinal y en células mesenquimales y amnióticas. [Internet] [Thesis]. Universidad de Valladolid; 2015. [cited 2021 Jan 22]. Available from: http://uvadoc.uva.es/handle/10324/17978.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Valsero Herguedas ME. Efecto neurotrófico "in vivo" del fluido cerebroespinal embrionario durante el desarrollo de la médula espinal y en células mesenquimales y amnióticas. [Thesis]. Universidad de Valladolid; 2015. Available from: http://uvadoc.uva.es/handle/10324/17978

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

5. Martínez Figueroa, Antonio. Conduccion medular somatosensorial método indirecto de estudio de la conducción en la médula espinal .

Degree: 1998, Universidad da Coruña

URL: http://hdl.handle.net/2183/5572

Subjects/Keywords: Médula espinal

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Martínez Figueroa, A. (1998). Conduccion medular somatosensorial método indirecto de estudio de la conducción en la médula espinal . (Doctoral Dissertation). Universidad da Coruña. Retrieved from http://hdl.handle.net/2183/5572

Chicago Manual of Style (16^th Edition):

Martínez Figueroa, Antonio. “Conduccion medular somatosensorial método indirecto de estudio de la conducción en la médula espinal .” 1998. Doctoral Dissertation, Universidad da Coruña. Accessed January 22, 2021. http://hdl.handle.net/2183/5572.

MLA Handbook (7^th Edition):

Martínez Figueroa, Antonio. “Conduccion medular somatosensorial método indirecto de estudio de la conducción en la médula espinal .” 1998. Web. 22 Jan 2021.

Vancouver:

Martínez Figueroa A. Conduccion medular somatosensorial método indirecto de estudio de la conducción en la médula espinal . [Internet] [Doctoral dissertation]. Universidad da Coruña; 1998. [cited 2021 Jan 22]. Available from: http://hdl.handle.net/2183/5572.

Council of Science Editors:

Martínez Figueroa A. Conduccion medular somatosensorial método indirecto de estudio de la conducción en la médula espinal . [Doctoral Dissertation]. Universidad da Coruña; 1998. Available from: http://hdl.handle.net/2183/5572

Universidad Andrés Bello

6. Anguita Salinas, Consuelo. Caracterización del crecimiento y renovación axonal durante la regeneración de la médula espinal en larvas de pez cebra .

Degree: 2016, Universidad Andrés Bello

URL: http://repositorio.unab.cl/xmlui/handle/ria/3697

► La regeneración neuronal es uno de los temas más relevantes en investigación biomédica ya que representa uno de los desafíos más complejos para la medicina… (more)

Subjects/Keywords: Pez Cebra; Médula Espinal

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APA (6^th Edition):

Anguita Salinas, C. (2016). Caracterización del crecimiento y renovación axonal durante la regeneración de la médula espinal en larvas de pez cebra . (Thesis). Universidad Andrés Bello. Retrieved from http://repositorio.unab.cl/xmlui/handle/ria/3697

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Anguita Salinas, Consuelo. “Caracterización del crecimiento y renovación axonal durante la regeneración de la médula espinal en larvas de pez cebra .” 2016. Thesis, Universidad Andrés Bello. Accessed January 22, 2021. http://repositorio.unab.cl/xmlui/handle/ria/3697.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Anguita Salinas, Consuelo. “Caracterización del crecimiento y renovación axonal durante la regeneración de la médula espinal en larvas de pez cebra .” 2016. Web. 22 Jan 2021.

Vancouver:

Anguita Salinas C. Caracterización del crecimiento y renovación axonal durante la regeneración de la médula espinal en larvas de pez cebra . [Internet] [Thesis]. Universidad Andrés Bello; 2016. [cited 2021 Jan 22]. Available from: http://repositorio.unab.cl/xmlui/handle/ria/3697.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Anguita Salinas C. Caracterización del crecimiento y renovación axonal durante la regeneración de la médula espinal en larvas de pez cebra . [Thesis]. Universidad Andrés Bello; 2016. Available from: http://repositorio.unab.cl/xmlui/handle/ria/3697

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidad de Chile

7. Caballero Fink, Stephanie. Efecto de la manipulación vertebral cervical alta en la variabilidad de la frecuencia cardíaca.

Degree: 2012, Universidad de Chile

URL: http://repositorio.uchile.cl/handle/2250/117005

► Al sistema nervioso autónomo se le atribuye en parte el control de la ritmicidad cardíaca a través de sus ramas, simpática y parasimpática. Existen diversos… (more)

▼ Al sistema nervioso autónomo se le atribuye en parte el control de la ritmicidad cardíaca a través de sus ramas, simpática y parasimpática. Existen diversos factores que son capaces de otorgarle variabilidad al ritmo cardíaco y esto se puede cuantificar gracias al análisis de la variabilidad de la frecuencia cardíaco, el cual entrega información en dos dominios, tiempo y frecuencia. Por otra parte, la columna cervical alta posee una relación anatómica directa con raíces nerviosas que forman parte del sistéma nervioso autónomo. Además se sabe que la manipulación vertebral es un método seguro de corregir disfunciones neurales provenientes de desajustes de segmentos vertebrales. El objetivo principal de esta investigación fue cuantificar y describir los valores del dominio frecuencia de la variabilidad de la frecuancia cardíaca de 24 sujetos jóvenes sanos, los cuales fueron citados por conveniencia a dos sesiones, en una de ellas recibieron una manipulación vertebral y en la otra sólo una movilización del segmento a evaluar. El diseño de investigación fue pre experimental, siendo cada sujeto su propio parámetro de comparación. La información recolectada se analizó estadísticamente, comparando los valores obtenidos antes y después de cada intervención, sin encontrar cambios significativos en los valores de variabilidad de los sujetos, luego de ser sometidos a una manipulación vertebral. Sin embargo, se hace necesaria la continua investigación de este ámbito, con el fin de profundizar en el conocimiento de este comportamiento fisiológico.; The cardiac rhythmicity is partially attributed to the autonomic nervous system, through his sympathetic and parasympathetic branches. There are some factors capable of giving certain variability to this rhythmicity, and this can be quantified through heart rate variability analysis, that gives information in two domains, time and frequency. On the other side, high cervical spine has direct anatomical relationship with some nerve roots, which form parts of the parasympathetic branch. Also, spine manipulation is well known as a safe correcting method of neural dysfunctions from spine segments. The main objective of this investigation was to quantify, describe and compare the values of the heart rate variability frequency domain of 24 young healthy subjects who were called by convenience twice for separate sessions, in one of them they received a spinal manipulation and in the other one just a mobilization of the evaluated segment. The investigation design was pre experimental, i.e. each subject’s parameters were used for comparison. Statistical analysis was performed to the collected data, comparing the values obtained before and after each intervention. No significant changes were found on subject’s variability after a spinal manipulation, nevertheless, more investigation on this scope is necessary to increase the knowledge on this physiological behavior.

Subjects/Keywords: Manipulación espinal; Frecuencia cardíaca

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Caballero Fink, S. (2012). Efecto de la manipulación vertebral cervical alta en la variabilidad de la frecuencia cardíaca. (Thesis). Universidad de Chile. Retrieved from http://repositorio.uchile.cl/handle/2250/117005

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Caballero Fink, Stephanie. “Efecto de la manipulación vertebral cervical alta en la variabilidad de la frecuencia cardíaca.” 2012. Thesis, Universidad de Chile. Accessed January 22, 2021. http://repositorio.uchile.cl/handle/2250/117005.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Caballero Fink, Stephanie. “Efecto de la manipulación vertebral cervical alta en la variabilidad de la frecuencia cardíaca.” 2012. Web. 22 Jan 2021.

Vancouver:

Caballero Fink S. Efecto de la manipulación vertebral cervical alta en la variabilidad de la frecuencia cardíaca. [Internet] [Thesis]. Universidad de Chile; 2012. [cited 2021 Jan 22]. Available from: http://repositorio.uchile.cl/handle/2250/117005.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Caballero Fink S. Efecto de la manipulación vertebral cervical alta en la variabilidad de la frecuencia cardíaca. [Thesis]. Universidad de Chile; 2012. Available from: http://repositorio.uchile.cl/handle/2250/117005

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

8. Chávez Asmat, Roberto Jesús. Aplicación de Pancreatina en modelo de lesión medular experimental como medio de regeneración neuronal.

Degree: 2011, National University of San Marcos

URL: http://hdl.handle.net/20.500.12672/462

► – Objective: To determine the degradation of glial scar and the presence of neuronal regeneration in rabbits with experimental spinal cord injury who received application… (more)

▼ – Objective: To determine the degradation of glial scar and the presence of neuronal regeneration in rabbits with experimental spinal cord injury who received application of pancreatin. Design: Experimental. Institution: Faculty of Medicine-San Marcos, Small Animal Clinic-San Marcos University, Institute of Pharmaceutical Sciences and Natural Resources "Juan de Dios Guevara", National Institute of Neurological Sciences, Centre for Magnetic Resonance-DIPSAC, Lima. Biological materials: New Zealand rabbits (n = 12) Methods: We divided into two phases, first with a biochemical method for the determination of glial scar degradation effect by pancreatin and the second with an in vivo method, which reproduces the model Hashimoto spinal cord injury after two months, made the formation of 2 groups at random, an enzyme group (receiving 5 mg of pancreatin in 100 µL 0.1 M phosphate buffer pH 6.7 intrathecally) and a control group ( received 100 µL 0.1 M phosphate buffer pH 6.7 intrathecally) both for a period of 21 days. The experimental animals were evaluated before, after injury and during the administration of the enzyme with the clinical trials BBB (Basso, Beattie and Bresnahan), Tarlov, open-field activity, inclined plane and cylinder. Scores were compared in clinical trials as well as histopathological findings through non-parametric Wilcoxon and Mann-Whitney test. For the study was considered a confidence level of 95%. Results: Clinical evaluations performed at regular intervals on days 0, 7, 14 and 21 for the application of pancreatin (enzyme group) and phosphate buffer (control group) showed no statistically significant difference between groups. Was obtained in the enzyme group lower cavity area expressed in mm2 and percentage with respect to control this being a significant difference (p = 0.008 and p = 0.042 respectively). There was obtained between the enzyme and control group a significant difference in connective tissue content, the presence of astrocytes and myelinated area (p = 0.222, p = 0.421 and p = 1,000 respectively). In the control group does not appear axonogenesis or very little in comparison of the enzyme group that has more dimensions of axonogenesis and even evidence of amputation neuromas. Conclusion: The pancreatin applied in experimental spinal cord injury promotes the reduction of intramedullary cavities and axonogenesis type neuronal regeneration. – Keywords: Spinal cord injury, experimental model, neuronal regeneration and pancreatin Advisors/Committee Members: Effio Imán, Pablo Humberto (advisor).

Subjects/Keywords: Médula espinal - Heridas y lesiones; Médula espinal - Regeneración; Pancreatina

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APA (6^th Edition):

Chávez Asmat, R. J. (2011). Aplicación de Pancreatina en modelo de lesión medular experimental como medio de regeneración neuronal. (Thesis). National University of San Marcos. Retrieved from http://hdl.handle.net/20.500.12672/462

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Chávez Asmat, Roberto Jesús. “Aplicación de Pancreatina en modelo de lesión medular experimental como medio de regeneración neuronal.” 2011. Thesis, National University of San Marcos. Accessed January 22, 2021. http://hdl.handle.net/20.500.12672/462.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Chávez Asmat, Roberto Jesús. “Aplicación de Pancreatina en modelo de lesión medular experimental como medio de regeneración neuronal.” 2011. Web. 22 Jan 2021.

Vancouver:

Chávez Asmat RJ. Aplicación de Pancreatina en modelo de lesión medular experimental como medio de regeneración neuronal. [Internet] [Thesis]. National University of San Marcos; 2011. [cited 2021 Jan 22]. Available from: http://hdl.handle.net/20.500.12672/462.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Chávez Asmat RJ. Aplicación de Pancreatina en modelo de lesión medular experimental como medio de regeneración neuronal. [Thesis]. National University of San Marcos; 2011. Available from: http://hdl.handle.net/20.500.12672/462

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Univerzitet u Beogradu

9. Milenković, Petar P., 1982-. Age estimation based on analyses of sternal end of clavicle and the first costal cartilage.

Degree: Medicinski fakultet, 2015, Univerzitet u Beogradu

URL: https://fedorabg.bg.ac.rs/fedora/get/o:9761/bdef:Content/get

►

MEDICINE – Skeletal Biology / MEDICINA – Biologija skeleta

In order to establish reliable age indicator in the period when all other epiphyseal age indicators… (more)

▼

MEDICINE – Skeletal Biology / MEDICINA – Biologija skeleta

In order to establish reliable age indicator in the period when all other epiphyseal age indicators have already been inactivated medial clavicle as the bone with the longest period of growth became the object of various investigations. However, the lack of population-specific method often made it unreliable in some population groups. The influence of socioeconomic conditions as well as interethnic and interracial variation on skeletal epiphyseal union phases has been acknowledged in scientific literature. Therefore, the importance of developing reliable population-specific age estimation methodology for the specific geographic region is outlined. The ossification patterns of the first costal cartilage represent another interesting feature of the same anatomical region which according to its position in human body is accessible for examinations in living individuals who undergo conventional radiographic and computed tomography examinations in the same field of view as clavicle. The broad range of macroscopic, histomorphometric and radiological analyses were conducted in order to establish the reliable age indicator. However, it remained unclear whether introduction of new more precise anatomical and other criteria in analyses of the medial clavicle and the first costal cartilage as well as their mutual analyses would be beneficial for age estimation. Therefore, this study encompassed our local population and was carried out with aim to examine whether morphological, radiological and histological analysis of medial clavicles as well as radiological examination of the first costal cartilage could be applied with success in age assessment of individuals. The study was composed of two sections. The first part of the study encompassed the collection of medial clavicles which was founded in cooperation of Laboratory for Anthropology, Institute of Anatomy with the Institute of Forensic Medicine, School of Medicine, University of Belgrade. The sample comprised 67 medial clavicles derived from individuals of different sex with age range from 20 to 90 years...

Advisors/Committee Members: Nikolić, Slobodan, 1965-.

Subjects/Keywords: ključna kost; prvo rebro; rebarna hrskavica; makroskopski; histomorfometrijski; radiološki; CT; pol; utvrđivanje starosti

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APA (6^th Edition):

Milenković, Petar P., 1. (2015). Age estimation based on analyses of sternal end of clavicle and the first costal cartilage. (Thesis). Univerzitet u Beogradu. Retrieved from https://fedorabg.bg.ac.rs/fedora/get/o:9761/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Milenković, Petar P., 1982-. “Age estimation based on analyses of sternal end of clavicle and the first costal cartilage.” 2015. Thesis, Univerzitet u Beogradu. Accessed January 22, 2021. https://fedorabg.bg.ac.rs/fedora/get/o:9761/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Milenković, Petar P., 1982-. “Age estimation based on analyses of sternal end of clavicle and the first costal cartilage.” 2015. Web. 22 Jan 2021.

Vancouver:

Milenković, Petar P. 1. Age estimation based on analyses of sternal end of clavicle and the first costal cartilage. [Internet] [Thesis]. Univerzitet u Beogradu; 2015. [cited 2021 Jan 22]. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:9761/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Milenković, Petar P. 1. Age estimation based on analyses of sternal end of clavicle and the first costal cartilage. [Thesis]. Univerzitet u Beogradu; 2015. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:9761/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade do Rio Grande do Sul

10. Horst, Andréa. Efeito da N-acetilcisteína sobre proteínas de sinalização e parâmetros oxidativos em medula espinal de ratos com dor neuropática.

Degree: 2017, Universidade do Rio Grande do Sul

URL: http://hdl.handle.net/10183/170680

► Introdução: A dor neuropática (dor originada como consequência direta de uma lesão ou doença afetando o sistema somatossensorial, em seus elementos periféricos ou no sistema… (more)

▼ Introdução: A dor neuropática (dor originada como consequência direta de uma lesão ou doença afetando o sistema somatossensorial, em seus elementos periféricos ou no sistema nervoso central - SNC) possui uma alta incidência na população mundial e afeta a qualidade da vida dos pacientes acometidos por ela. O tratamento dessa condição dolorosa é ainda um desafio aos profissionais da saúde, pois os fármacos usados possuem ação limitada e diversos efeitos colaterais. Assim, há um grande interesse na busca por novos fármacos para tratar dor neuropática. Os estudos mostram o envolvimento das espécies reativas de oxigênio (EROs) nos distintos tipos de dor, incluindo a neuropática. Dado ao envolvimento dessas espécies, moléculas com ação antioxidante são fortes candidatas como coadjuvantes no tratamento de condições dolorosas. Diversos estudos mostraram que a administração de N-acetilcisteína (NAC), uma molécula com ações complexas, dentre elas a de antioxidante, produz antinocicepção em animais com constrição crônica no nervo isquiático (CCI, do inglês chronic constriction injury), um modelo de dor neuropática. Contudo, ainda são pouco conhecidos os mecanismos envolvidos no efeito antinociceptivo da NAC. Dessa forma, o presente estudo teve como objetivo avaliar os efeitos temporais da administração intraperitoneal de solução salina e NAC, na dose de 150 mg/kg/dia, dado por 1, 3 ou 7 dias, sobre indicadores de comportamento nociceptivo e de recuperação de função locomotora, e moléculas de sinalização celular e parâmetros de estresse oxidativo em medula espinal lombossacral de ratos sem e com CCI. Esse segmento da medula espinal foi escolhido por ser a região de entrada das informações aferentes do nervo isquiático. O projeto que antecedeu o presente estudo foi aprovado pela Comissão de Ética no uso de animais da UFRGS (número de protocolo: 23407). Metodologia: Foram utilizados 180 ratos Wistar machos, pesando 200-300g, divididos em 3 grupos experimentais: controle (animais que não sofreram nenhuma intervenção cirúrgica), sham (animais que tiveram o nervo isquiático direito apenas exposto) e CCI (animais que tiveram o nervo isquiático direito exposto e recebeu 4 amarraduras em seu terço inicial). Estes grupos experimentais foram subdivididos em subgrupos que receberam administração X intraperitoneal de solução salina ou NAC, na dose de 150 mg/kg/dia, por período de 1, 3 ou 7 dias. Os testes de von Frey eletrônico e do índice funcional do isquiático (IFI) avaliaram a sensibilidade mecânica e a recuperação funcional do nervo, respectivamente, nos períodos antes da lesão e 1, 3 e 7 dias após a lesão nervosa. Ao final dos períodos de 1, 3 e 7 dias, os animais foram mortos por decapitação e a medula espinal lombossacral retirada e usada para as determinações: formação do ânion superóxido, hidroperóxidos lipídicos, capacidade antioxidante total (TAC, do inglês total antioxidante capacity), ácido ascórbico, expressão da proteína p-38 fosforilada, e quantificação do RNA mensageiro (mRNA) do NFкB. Outros grupos de animais foram… Advisors/Committee Members: Partata, Wania Aparecida.

Subjects/Keywords: Acetilcisteína; Neuralgia; Nociceptividade; Nervo isquiático; Medula espinal

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Horst, A. (2017). Efeito da N-acetilcisteína sobre proteínas de sinalização e parâmetros oxidativos em medula espinal de ratos com dor neuropática. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/170680

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Horst, Andréa. “Efeito da N-acetilcisteína sobre proteínas de sinalização e parâmetros oxidativos em medula espinal de ratos com dor neuropática.” 2017. Thesis, Universidade do Rio Grande do Sul. Accessed January 22, 2021. http://hdl.handle.net/10183/170680.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Horst, Andréa. “Efeito da N-acetilcisteína sobre proteínas de sinalização e parâmetros oxidativos em medula espinal de ratos com dor neuropática.” 2017. Web. 22 Jan 2021.

Vancouver:

Horst A. Efeito da N-acetilcisteína sobre proteínas de sinalização e parâmetros oxidativos em medula espinal de ratos com dor neuropática. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2017. [cited 2021 Jan 22]. Available from: http://hdl.handle.net/10183/170680.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Horst A. Efeito da N-acetilcisteína sobre proteínas de sinalização e parâmetros oxidativos em medula espinal de ratos com dor neuropática. [Thesis]. Universidade do Rio Grande do Sul; 2017. Available from: http://hdl.handle.net/10183/170680

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat de Valencia

11. Navarré Gimeno, Aránzazu. Estudio de la afectación medular en la Esclerosis Múltiple. Establecimiento de patrones de lesión en neuroimagen y su relación con la discapacidad.

Degree: 2015, Universitat de Valencia

URL: http://hdl.handle.net/10550/50732

► La Esclerosis Múltiple (EM) es una enfermedad de evolución muy variable sin factores pronósticos de discapacidad claramente definidos. La médula espinal es una localización relevante… (more)

▼ La Esclerosis Múltiple (EM) es una enfermedad de evolución muy variable sin factores pronósticos de discapacidad claramente definidos. La médula espinal es una localización relevante para el desarrollo de discapacidad física en los pacientes con EM. Por su estructura, es esperable que sea clínicamente elocuente; sin embargo, en la EM es frecuente encontrar afectación medular silente por resonancia magnética (RM), siendo relevante para el diagnóstico de la enfermedad, pero su relación con el desarrollo de la discapacidad no se ha demostrado claramente, lo cual contribuye a la disociación clínico-radiológica de esta enfermedad. La RM es la herramienta diagnóstica más sensible en la EM. El uso y las secuencias de la RM cerebral está bien estandarizado, pero existe controversia sobre la necesidad de realizar estudio de RM medular a los pacientes con EM y no existe consenso sobre las secuencias óptimas. La médula espinal ha sido poco estudiada por RM hasta hace unos años debido a dificultades técnicas puesto que la adquisición de la imagen es susceptible de artefactos de campo magnético y de movimiento y a la falta de consenso en la necesidad de su estudio. La región cervical de la médula es la que más frecuentemente se afecta en la EM y la menos susceptible a los artefactos de movimiento en la adquisición de la imagen; además, se ha observado que la afectación dorsal puede predecirse por el grado de afectación cervical. Por ello, los estudios de RM en EM se restringen habitualmente a la ME cervical con el propósito de optimizar los recursos económicos y de tiempo de adquisición de la imagen. La afectación medular en la EM puede ser focal y/o difusa; se ha relacionado clásicamente la forma difusa con las formas progresivas de la enfermedad. Además, aunque es esperable que exista una interrelación entre la afectación cerebral y medular en los pacientes con EM dado que se trata de una misma enfermedad que afecta a todo el SNC, parece que las alteraciones en cerebro y médula suceden de forma independiente, no habiéndose encontrado relación en estudios anatomo-patológicos entre la carga lesional cerebral y el daño axonal en los tractos espinales. Por otra parte, la RM medular convencional no es capaz de detectar el sustrato patológico de la afectación focal y difusa que acontece en la EM a nivel de la médula espinal, con lo que su papel como factor predictor de discapacidad es controvertido. En los últimos 10-15 años ha adquirido interés el estudio de la médula espinal en la EM, desarrollándose mejoras técnicas en la adquisición de la imagen convencional e investigándose nuevas técnicas de imagen cuantitativas como el estudio de la atrofia espinal que se ha relacionado con la discapacidad en estudios en pacientes con EM de larga evolución y en pacientes con formas progresivas de la enfermedad. Además, si bien se puede detectar atrofia espinal en EM recurrentes precoces, parece que en estos estadíos iniciales, la variabilidad estructural de la médula y la carga lesional cervical explican la discapacidad mejor que la propia… Advisors/Committee Members: Coret Ferrer, Francisco (advisor).

Subjects/Keywords: esclerosis múltiple; médula espinal; discapacidad; resonancia magnética

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Navarré Gimeno, A. (2015). Estudio de la afectación medular en la Esclerosis Múltiple. Establecimiento de patrones de lesión en neuroimagen y su relación con la discapacidad. (Doctoral Dissertation). Universitat de Valencia. Retrieved from http://hdl.handle.net/10550/50732

Chicago Manual of Style (16^th Edition):

Navarré Gimeno, Aránzazu. “Estudio de la afectación medular en la Esclerosis Múltiple. Establecimiento de patrones de lesión en neuroimagen y su relación con la discapacidad. ” 2015. Doctoral Dissertation, Universitat de Valencia. Accessed January 22, 2021. http://hdl.handle.net/10550/50732.

MLA Handbook (7^th Edition):

Navarré Gimeno, Aránzazu. “Estudio de la afectación medular en la Esclerosis Múltiple. Establecimiento de patrones de lesión en neuroimagen y su relación con la discapacidad. ” 2015. Web. 22 Jan 2021.

Vancouver:

Navarré Gimeno A. Estudio de la afectación medular en la Esclerosis Múltiple. Establecimiento de patrones de lesión en neuroimagen y su relación con la discapacidad. [Internet] [Doctoral dissertation]. Universitat de Valencia; 2015. [cited 2021 Jan 22]. Available from: http://hdl.handle.net/10550/50732.

Council of Science Editors:

Navarré Gimeno A. Estudio de la afectación medular en la Esclerosis Múltiple. Establecimiento de patrones de lesión en neuroimagen y su relación con la discapacidad. [Doctoral Dissertation]. Universitat de Valencia; 2015. Available from: http://hdl.handle.net/10550/50732

Universitat de Valencia

12. Tornero Tornero, Juan Carlos. Efecto de la duloxetina sobre la expresión de fos en el tronco del encéfalo y en la médula espinal de la rata en modelos de dolor persistente .

Degree: 2015, Universitat de Valencia

URL: http://hdl.handle.net/10550/50955

► A pesar de los ensayos clínicos en humanos que avalan el uso clínico de la duloxetina en dolor neuropático, todavía no se conoce en profundidad… (more)

▼ A pesar de los ensayos clínicos en humanos que avalan el uso clínico de la duloxetina en dolor neuropático, todavía no se conoce en profundidad el sustrato anatómico en el que subyace el efecto analgésico de este antidepresivo. Nuestra revisión bibliográfica sobre el tema no ha ofrecido ni un solo trabajo en el que se pretenda identificar las estructuras neurales supraespinales que se activan o al menos se ven alteradas tras la administración de duloxetina en animales sanos, o con diferentes tipos de dolor neuropático. Parece, sin embargo, que la identificación de los centros troncoencefálicos que ven alterada su actividad neuronal por la administración de estas sustancias, sería de gran utilidad para una mejor compresión de sus mecanismos de acción, lo que permitiría mejorar su eficacia tanto empleado de forma individual como en posibles combinaciones con otros fármacos analgésicos. Basados en su mecanismo de acción, la inhibición de la recaptación de serotonina y noradrenalina, nuestro estudio se centra en estudiar el papel que el principal núcleo serotoninérgico, el núcleo dorsal del rafe (DR), y el principal núcleo noradrenérgico, el locus coeruleus (LC), juegan en el efecto analgésico de la duloxetina. Nuestra hipótesis de trabajo defiende, por un lado, que las ratas con lesión nerviosa producida por el modelo de constricción crónica del ciático (CCI) a las que se introduzca un tratamiento con duloxetina presentarán analgesia respecto a las ratas a las que se aplique este modelo y se traten con vehículo. Por otro lado, teniendo en cuenta el mecanismo de acción conocido de la duloxetina (inhibición de la recaptación de serotonina y noradrenalina), esperamos que los principales núcleos noradrenérgico y serotoninérgico troncoencefálicos vean significativamente alterada su actividad tras la administración de la duloxetina en el modelo de dolor neuropático empleado, y que dicho efecto, se refleje a nivel medular. Los objetivos de este trabajo son varios: 1º: Comprobar si el tratamiento con duloxetina reduce o no la alodinia y/o la hiperalgesia inducida en los animales de experimentación por la aplicación del modelo de dolor neuropático CCI. 2º: Comprobar si el tratamiento con duloxetina reduce o no la actividad neuronal inducida en el asta posterior de la médula espinal de los animales de experimentación por la aplicación del modelo de dolor neuropático CCI. 3º: Comprobar si el tratamiento con duloxetina modifica o no la actividad neuronal en los centros troncoencefálicos seleccionados para este estudio (el DR y el LC), tanto en animales a los que se aplique un estímulo nociceptivo (CCI) como a los que no. Para alcanzar nuestros objetivos empleamos test conductuales de medida de alodinia e hiperalgesia (Electro Von Frey y Randall y Sellito). Asimismo, analizamos mediante inmunodetección de la proteína Fos, ampliamente utilizada como marcador de actividad neuronal en estudios de dolor, el efecto de la duloxetina en la actividad neuronal de los centros neurales objeto del estudio. El interés de alcanzar los… Advisors/Committee Members: Valverde Navarro, Alfonso A (advisor).

Subjects/Keywords: dolor persistente; duloxetina; fos; medula espinal

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Tornero Tornero, J. C. (2015). Efecto de la duloxetina sobre la expresión de fos en el tronco del encéfalo y en la médula espinal de la rata en modelos de dolor persistente . (Doctoral Dissertation). Universitat de Valencia. Retrieved from http://hdl.handle.net/10550/50955

Chicago Manual of Style (16^th Edition):

Tornero Tornero, Juan Carlos. “Efecto de la duloxetina sobre la expresión de fos en el tronco del encéfalo y en la médula espinal de la rata en modelos de dolor persistente .” 2015. Doctoral Dissertation, Universitat de Valencia. Accessed January 22, 2021. http://hdl.handle.net/10550/50955.

MLA Handbook (7^th Edition):

Tornero Tornero, Juan Carlos. “Efecto de la duloxetina sobre la expresión de fos en el tronco del encéfalo y en la médula espinal de la rata en modelos de dolor persistente .” 2015. Web. 22 Jan 2021.

Vancouver:

Tornero Tornero JC. Efecto de la duloxetina sobre la expresión de fos en el tronco del encéfalo y en la médula espinal de la rata en modelos de dolor persistente . [Internet] [Doctoral dissertation]. Universitat de Valencia; 2015. [cited 2021 Jan 22]. Available from: http://hdl.handle.net/10550/50955.

Council of Science Editors:

Tornero Tornero JC. Efecto de la duloxetina sobre la expresión de fos en el tronco del encéfalo y en la médula espinal de la rata en modelos de dolor persistente . [Doctoral Dissertation]. Universitat de Valencia; 2015. Available from: http://hdl.handle.net/10550/50955

13. Montoto Marqués, Antonio. Lesión medular traumática en Galicia(1995-2014): estudio de la evolución epidemiológica y resultados clínico-funcionales .

Degree: 2018, Universidad da Coruña

URL: http://hdl.handle.net/2183/20926

► [Resumen] Introducción La incidencia mundial de la lesión medular traumática (LMT) es muy variable. Recientes estudios señalan que estamos asistiendo a un cambio epidemiológico de… (more)

▼ [Resumen] Introducción La incidencia mundial de la lesión medular traumática (LMT) es muy variable. Recientes estudios señalan que estamos asistiendo a un cambio epidemiológico de la LMT. Este cambio puede originar una serie de consecuencias en el modelo de atención. Conocer las características epidemiológicas y demográficas de la LMT es vital para planificar las prioridades, asignar los recursos sanitarios adecuados y también, para identificar las directrices de la prevención. Objetivo Determinar las características epidemiológicas de los pacientes con LMT en Galicia durante el periodo 1995-2014 y analizar la afectación neurológica y los factores determinantes de la evolución clínica y funcional en dicho periodo. Material y método Se realizó un estudio observacional con seguimiento retrospectivo y prospectivo de los pacientes con lesión medular de etiología traumática que ingresaron en la Unidad de Lesionados Medulares (ULM) del Complejo Hospitalario Universitario de A Coruña en el período comprendido entre enero de 1995 y diciembre del 2014. Se estudiaron variables socio-demográficas, comorbilidad según el índice de Charlson, etiología, variables de la exploración neurológica según la clasificación ASIA/ISCOS de la lesión medular, tipo de lesión ósea, lesiones asociadas, manejo terapéutico, ingreso en UCI, funcionalidad según la escala Spinal Cord Independence Measure III (SCIM III), capacidad de marcha y escala de marcha de la LM Walking Index Spinal Cord Injury II (WISCI II), destino y tratamiento rehabilitador al alta hospitalaria, y mortalidad. El análisis estadístico se realizó mediante el programa SPSS 19.0. Se efectuó un estudio descriptivo de las variables, expresando las variables cuantitativas como media ± desviación típica y las cualitativas como valor absoluto y porcentaje, con una estimación de su 95% de intervalo de confianza. La comparación de medias se realizó por medio de la t-Student o el test de Mann-Whitney. La comparación múltiple de media se efectuó mediante el ANOVA o el test de Kruskal-Wallis. La asociación de las variables cualitativas se estimó por medio del estadístico Chi cuadrado y la correlación entre variables cuantitativas por medio del coeficiente de correlación de Pearson o Spearman. Se calcularon las tasas de incidencia cruda para cada tipo de lesión, y las tasas estandarizadas ajustadas por edad por el método directo, siendo expresadas como tasas/100.000 habitantes/año. Para el análisis de tendencias de las tasas se utilizaron modelos de regresión 'joinpoint'. Para determinar qué variables se asocian a los eventos de interés realizamos análisis multivariado de regresión lineal múltiple y logística. Se determinó la supervivencia de los pacientes utilizando la metodología de Kaplan-Meier y un modelo de riesgos proporcionales de Cox. Advisors/Committee Members: Toro Santos, Francisco Javier de (advisor).

Subjects/Keywords: Médula espinal-Lesiones y heridas-Epidemiología; Médula espinal-Lesiones y heridas-Pacientes-Investigación-Galicia

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Montoto Marqués, A. (2018). Lesión medular traumática en Galicia(1995-2014): estudio de la evolución epidemiológica y resultados clínico-funcionales . (Doctoral Dissertation). Universidad da Coruña. Retrieved from http://hdl.handle.net/2183/20926

Chicago Manual of Style (16^th Edition):

Montoto Marqués, Antonio. “Lesión medular traumática en Galicia(1995-2014): estudio de la evolución epidemiológica y resultados clínico-funcionales .” 2018. Doctoral Dissertation, Universidad da Coruña. Accessed January 22, 2021. http://hdl.handle.net/2183/20926.

MLA Handbook (7^th Edition):

Montoto Marqués, Antonio. “Lesión medular traumática en Galicia(1995-2014): estudio de la evolución epidemiológica y resultados clínico-funcionales .” 2018. Web. 22 Jan 2021.

Vancouver:

Montoto Marqués A. Lesión medular traumática en Galicia(1995-2014): estudio de la evolución epidemiológica y resultados clínico-funcionales . [Internet] [Doctoral dissertation]. Universidad da Coruña; 2018. [cited 2021 Jan 22]. Available from: http://hdl.handle.net/2183/20926.

Council of Science Editors:

Montoto Marqués A. Lesión medular traumática en Galicia(1995-2014): estudio de la evolución epidemiológica y resultados clínico-funcionales . [Doctoral Dissertation]. Universidad da Coruña; 2018. Available from: http://hdl.handle.net/2183/20926

Universidade do Rio Grande do Norte

14. Lima, Rafaelly Lira Cavalcanti. Reúso da água produzida na fabricação de fluidos de perfuração base emulsão inversa e sua influência nas propriedades do fluido .

Degree: 2019, Universidade do Rio Grande do Norte

URL: http://repositorio.ufrn.br/handle/123456789/28542

► Oil production plays an important role for the economy and society development. However, the waste generated from the production to exploration need to be minimized,… (more)

▼ Oil production plays an important role for the economy and society development. However, the waste generated from the production to exploration need to be minimized, once that toxic waste is produced and cannot be disposed into the environment. The search for treatment and adequate reuse for waste such as drilling fluids and produced water prevent severe damage. In the oil industry, drilling fluid is critical for a good drilling, due to the required pressures and need to clean the well. However, the high volumes of fluids after this drilling stage become waste, just as the water produced in the production phase is a high volume residue. Reducing the environmental liabilities generated in the production of drilling fluids, with the reuse of water produced in the formulation of non-aqueous base fluids containing synthetic olefin, an example that the oil industry can reinvent itself and work to absorb their own waste. Thus, clean water consumption in the new formulations is avoided and reduces the final volume of waste, considering the different stages until oil production. The objective of this work was to formulate drilling fluids using produced water and study its properties. Thus, non-aqueous drilling fluids were formulated and tested in this study, containing between 20- 40% of water produced without treatment. The aqueous phase of these fluids is usually constituted by a brine, due to the required inhibition potential. The same inhibition criterion was applied to the produced water (PW), being the clay swelling analyzed in a Linear Swell Meter, and compared the brines applied to non-aqueous fluids. The PW simulated a residue containing emulsified oil, thus, presenting a high degree of difficulty for its treatment. Through factorial experimental planning 33 it was possible to verify the influence of the residue, and additives such as emulsifier and viscosifying on the rheological parameters and electrical stability. A rheometer was used to obtain rheological data of great quality and a potentiostate was used for corrosion analyses of the produced water and fluids. Comparisons between the fluids already used today and those prepared with the different PW were performed. The tests showed that although the produced water was corrosive, it does not affect the corrosion potential of the drilling fluids because the residue was emulsified. Thus, since the drilling fluid must meet the needs of the drilling operation and develop its function satisfactorily in relation to rheological parameters such as flow limit, plastic viscosity and gels. Commercial software has been applied to simulate the cleaning efficiency of a well with offshore characteristics, in relation to its geometry. According to the directional simulation, the last phase corresponds to the open well and starts in a horizontal stretch of 90°. The fluids formulated with produced water revealed similar corrosion and performance equivalent to those currently applied. For all the flows studied, the simulation showed satisfactory… Advisors/Committee Members: Dantas, Tereza Neuma de Castro (advisor).

Subjects/Keywords: Reúso de água produzida; Fluido de perfuração; Fluido não aquoso; Fluido base olefina

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APA (6^th Edition):

Lima, R. L. C. (2019). Reúso da água produzida na fabricação de fluidos de perfuração base emulsão inversa e sua influência nas propriedades do fluido . (Masters Thesis). Universidade do Rio Grande do Norte. Retrieved from http://repositorio.ufrn.br/handle/123456789/28542

Chicago Manual of Style (16^th Edition):

Lima, Rafaelly Lira Cavalcanti. “Reúso da água produzida na fabricação de fluidos de perfuração base emulsão inversa e sua influência nas propriedades do fluido .” 2019. Masters Thesis, Universidade do Rio Grande do Norte. Accessed January 22, 2021. http://repositorio.ufrn.br/handle/123456789/28542.

MLA Handbook (7^th Edition):

Lima, Rafaelly Lira Cavalcanti. “Reúso da água produzida na fabricação de fluidos de perfuração base emulsão inversa e sua influência nas propriedades do fluido .” 2019. Web. 22 Jan 2021.

Vancouver:

Lima RLC. Reúso da água produzida na fabricação de fluidos de perfuração base emulsão inversa e sua influência nas propriedades do fluido . [Internet] [Masters thesis]. Universidade do Rio Grande do Norte; 2019. [cited 2021 Jan 22]. Available from: http://repositorio.ufrn.br/handle/123456789/28542.

Council of Science Editors:

Lima RLC. Reúso da água produzida na fabricação de fluidos de perfuração base emulsão inversa e sua influência nas propriedades do fluido . [Masters Thesis]. Universidade do Rio Grande do Norte; 2019. Available from: http://repositorio.ufrn.br/handle/123456789/28542

Universidade do Rio Grande do Norte

15. Costa, Rosimeire Filgueira. Contribuição da poliacrilamida parcialmente hidrolisada em associação com a bentonita em fluidos de perfuração aquosos .

Degree: 2015, Universidade do Rio Grande do Norte

URL: http://repositorio.ufrn.br/handle/123456789/20287

► In this study, we investigated the effect of addition of partially hydrolyzed polyacrylamide (HPAM) and bentonite in the physicochemical properties of acquous drilling fluids. Two… (more)

▼ In this study, we investigated the effect of addition of partially hydrolyzed polyacrylamide (HPAM) and bentonite in the physicochemical properties of acquous drilling fluids. Two formulations were evaluated: F1 formulation, which was used as reference, containing carboxymethylcellulose (CMC), magnesium oxide (MgO), calcite (calcium carbonate - CaCO3 ), xanthan gum, sodium chloride (NaCl) and triazine (bactericidal); and F2, containig HPAM steady of CMC and bentonite in substituition of calcite. The prepared fluids were characterized by rheological properties, lubricity and fluid loss. Calcite was characterized by granulometry and thermal gravimetric analysis (TGA). The formulation F2 presented filtration control at 93◦C 34 mL while F1 had total filtration. The lubricity coefficient was 0.1623 for F2 and 0.2542 for F1, causing reduction in torque of 25% for F1 and 52 % for F2, compared to water. In the temperature of 49 ◦C and shear rate of 1022 s −1 , the apparent viscosities were 25, 5 and 48 cP for F1 and F2 formulation, respectively, showing greater thermal resistance to F2. With the confirmation of higher thermal stability of F2, factorial design was conducted in order to determine the HPAM and of bentonite concentrations that resulted in the better performance of the fluids. The statistical design response surfaces indicated the best concentrations of HPAM (4.3g/L) and bentonite (28.5 g/L) to achieve improved properties of the fluids (apparent viscosity, plastic viscosity, yield point and fluid loss) with 95% confidence, as well as the correlations between these factors (HPAM and bentonite concentrations). The thermal aging tests indicated that the formulations containing HPAM and bentonite may be used to the maximum temperature until 150 ◦C. The analyze of the filter cake formed after filtration of fluids by X-ray diffraction showed specific interactions between the bentonite and HPAM, explaining the greater thermal stability of F2 compared to the fluid F1, that supports maximum temperature of 93 ◦C. Advisors/Committee Members: Balaban, Rosângela de Carvalho (advisor), 65946499734 (advisor), http://lattes.cnpq.br/7711521318854102 (advisor).

Subjects/Keywords: HPAM; Bentonita; Fluido de perfuração

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Costa, R. F. (2015). Contribuição da poliacrilamida parcialmente hidrolisada em associação com a bentonita em fluidos de perfuração aquosos . (Thesis). Universidade do Rio Grande do Norte. Retrieved from http://repositorio.ufrn.br/handle/123456789/20287

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Costa, Rosimeire Filgueira. “Contribuição da poliacrilamida parcialmente hidrolisada em associação com a bentonita em fluidos de perfuração aquosos .” 2015. Thesis, Universidade do Rio Grande do Norte. Accessed January 22, 2021. http://repositorio.ufrn.br/handle/123456789/20287.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Costa, Rosimeire Filgueira. “Contribuição da poliacrilamida parcialmente hidrolisada em associação com a bentonita em fluidos de perfuração aquosos .” 2015. Web. 22 Jan 2021.

Vancouver:

Costa RF. Contribuição da poliacrilamida parcialmente hidrolisada em associação com a bentonita em fluidos de perfuração aquosos . [Internet] [Thesis]. Universidade do Rio Grande do Norte; 2015. [cited 2021 Jan 22]. Available from: http://repositorio.ufrn.br/handle/123456789/20287.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Costa RF. Contribuição da poliacrilamida parcialmente hidrolisada em associação com a bentonita em fluidos de perfuração aquosos . [Thesis]. Universidade do Rio Grande do Norte; 2015. Available from: http://repositorio.ufrn.br/handle/123456789/20287

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade do Rio Grande do Norte

16. Costa, Rosimeire Filgueira. Contribuição da poliacrilamida parcialmente hidrolisada em associação com a bentonita em fluidos de perfuração aquosos .

Degree: 2015, Universidade do Rio Grande do Norte

URL: http://repositorio.ufrn.br/handle/123456789/20287

► In this study, we investigated the effect of addition of partially hydrolyzed polyacrylamide (HPAM) and bentonite in the physicochemical properties of acquous drilling fluids. Two… (more)

▼ In this study, we investigated the effect of addition of partially hydrolyzed polyacrylamide (HPAM) and bentonite in the physicochemical properties of acquous drilling fluids. Two formulations were evaluated: F1 formulation, which was used as reference, containing carboxymethylcellulose (CMC), magnesium oxide (MgO), calcite (calcium carbonate - CaCO3 ), xanthan gum, sodium chloride (NaCl) and triazine (bactericidal); and F2, containig HPAM steady of CMC and bentonite in substituition of calcite. The prepared fluids were characterized by rheological properties, lubricity and fluid loss. Calcite was characterized by granulometry and thermal gravimetric analysis (TGA). The formulation F2 presented filtration control at 93◦C 34 mL while F1 had total filtration. The lubricity coefficient was 0.1623 for F2 and 0.2542 for F1, causing reduction in torque of 25% for F1 and 52 % for F2, compared to water. In the temperature of 49 ◦C and shear rate of 1022 s −1 , the apparent viscosities were 25, 5 and 48 cP for F1 and F2 formulation, respectively, showing greater thermal resistance to F2. With the confirmation of higher thermal stability of F2, factorial design was conducted in order to determine the HPAM and of bentonite concentrations that resulted in the better performance of the fluids. The statistical design response surfaces indicated the best concentrations of HPAM (4.3g/L) and bentonite (28.5 g/L) to achieve improved properties of the fluids (apparent viscosity, plastic viscosity, yield point and fluid loss) with 95% confidence, as well as the correlations between these factors (HPAM and bentonite concentrations). The thermal aging tests indicated that the formulations containing HPAM and bentonite may be used to the maximum temperature until 150 ◦C. The analyze of the filter cake formed after filtration of fluids by X-ray diffraction showed specific interactions between the bentonite and HPAM, explaining the greater thermal stability of F2 compared to the fluid F1, that supports maximum temperature of 93 ◦C. Advisors/Committee Members: Balaban, Rosângela de Carvalho (advisor), 65946499734 (advisor), http://lattes.cnpq.br/7711521318854102 (advisor).

Subjects/Keywords: HPAM; Bentonita; Fluido de perfuração

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Costa, R. F. (2015). Contribuição da poliacrilamida parcialmente hidrolisada em associação com a bentonita em fluidos de perfuração aquosos . (Masters Thesis). Universidade do Rio Grande do Norte. Retrieved from http://repositorio.ufrn.br/handle/123456789/20287

Chicago Manual of Style (16^th Edition):

Costa, Rosimeire Filgueira. “Contribuição da poliacrilamida parcialmente hidrolisada em associação com a bentonita em fluidos de perfuração aquosos .” 2015. Masters Thesis, Universidade do Rio Grande do Norte. Accessed January 22, 2021. http://repositorio.ufrn.br/handle/123456789/20287.

MLA Handbook (7^th Edition):

Costa, Rosimeire Filgueira. “Contribuição da poliacrilamida parcialmente hidrolisada em associação com a bentonita em fluidos de perfuração aquosos .” 2015. Web. 22 Jan 2021.

Vancouver:

Costa RF. Contribuição da poliacrilamida parcialmente hidrolisada em associação com a bentonita em fluidos de perfuração aquosos . [Internet] [Masters thesis]. Universidade do Rio Grande do Norte; 2015. [cited 2021 Jan 22]. Available from: http://repositorio.ufrn.br/handle/123456789/20287.

Council of Science Editors:

Costa RF. Contribuição da poliacrilamida parcialmente hidrolisada em associação com a bentonita em fluidos de perfuração aquosos . [Masters Thesis]. Universidade do Rio Grande do Norte; 2015. Available from: http://repositorio.ufrn.br/handle/123456789/20287

Universidade do Rio Grande do Sul

17. Nicola, Fabrício do Couto. Associação de treino locomotor em esteira e células-tronco no tratamento da lesão medular experimental.

Degree: 2013, Universidade do Rio Grande do Sul

URL: http://hdl.handle.net/10183/75767

►

A lesão medular é considerada uma patologia incapacitante, para a qual até o momento não há tratamento eficaz. A lesão medular resulta em perda de… (more)

▼

A lesão medular é considerada uma patologia incapacitante, para a qual até o momento não há tratamento eficaz. A lesão medular resulta em perda de tecido, incluindo tratos de fibras mielinizadas que carregam informações motoras e sensoriais. Além dos déficits sensitivos e motores, existem as alterações viscerais e tróficas relacionadas com o nível da lesão e o tipo de lesão. O treino locomotor em esteira e o transplante de células-tronco têm sido utilizados como estratégias de recuperação no intuito de otimizar a recuperação da lesão medular experimental em ratos, porém, vêm sendo abordadas separadamente. O objetivo deste estudo é avaliar a eficácia do treino locomotor em esteira, do transplante de células-tronco mesenquimais de dente decíduo humano (SHEDs), e da combinação entre os tratamentos avaliando a recuperação da função motora e a regeneração medular após a lesão medular traumática em ratos Wistar machos utilizando o equipamento NYU Impactor. Os objetivos específicos foram comparar os efeitos do transplante de SHEDS com o treino locomotor em esteira e a combinação entre os tratamentos quanto à recuperação da função motora e histológica; demonstrar a possível diferenciação das SHEDs transplantadas, bem como a sua integração no tecido da medula lesada. Os resultados obtidos demonstram que o transplante de SHEDs e a combinação entre os tratamentos favorece a recuperação da função motora após a lesão medular em ratos Wistar, enquanto apenas o tratamento com o treino locomotor não se mostra eficaz. Observamos neuroproteção do tecido medular evidenciada pela redução da cavidade cística nos animais tratados com a combinação de transplante de SHEDs e o treino locomotor. Houve redução da cicatriz glial e aumento na expressão de neurofilamento médio (NF-M) no grupo SHEDs. As células transplantadas sobreviveram e se integraram ao tecido, não havendo indícios de diferenciação em astrócitos e/ou neurônios. Houve um aumento na cicatriz glial no grupo lesão e no grupo lesão tratado com treino locomotor, associado a maiores áreas de cavidade cística e baixa expressão de NF-M. A partir de nossos resultados, podemos concluir que o transplante de SHEDs, assim como a combinação entre transplante de SHEDs e treino locomotor, promovem a recuperação da função motora após lesão medular por contusão. Apesar da sobrevivência e integração das SHEDs ao tecido, não houve diferenciação em astrócitos e/ou neurônios. Apenas o transplante celular foi capaz de reduzir a cicatriz glial e manter a expressão de neurofilamento.

Spinal cord injury is a disabling traumatic condition and available therapeutic approaches are poorly effective. Spinal cord injury results in loss of tissue, including myelinated fiber tracts that carry sensory and motor information. In addition to motor and sensory deficits, there are visceral and trophic changes related to the level of injury and type of injury. In the search for new treatments, stem cells transplants and treadmill training have been studied separately to minimize spinal injury in experimental rats.…

Advisors/Committee Members: Netto, Carlos Alexandre.

Subjects/Keywords: Traumatismos da medula espinal; Transplante de células-tronco; Células-tronco mesenquimais; Condicionamento físico animal; Teste de esforço; Regeneração da medula espinal

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Nicola, F. d. C. (2013). Associação de treino locomotor em esteira e células-tronco no tratamento da lesão medular experimental. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/75767

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Nicola, Fabrício do Couto. “Associação de treino locomotor em esteira e células-tronco no tratamento da lesão medular experimental.” 2013. Thesis, Universidade do Rio Grande do Sul. Accessed January 22, 2021. http://hdl.handle.net/10183/75767.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Nicola, Fabrício do Couto. “Associação de treino locomotor em esteira e células-tronco no tratamento da lesão medular experimental.” 2013. Web. 22 Jan 2021.

Vancouver:

Nicola FdC. Associação de treino locomotor em esteira e células-tronco no tratamento da lesão medular experimental. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2013. [cited 2021 Jan 22]. Available from: http://hdl.handle.net/10183/75767.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Nicola FdC. Associação de treino locomotor em esteira e células-tronco no tratamento da lesão medular experimental. [Thesis]. Universidade do Rio Grande do Sul; 2013. Available from: http://hdl.handle.net/10183/75767

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat de Barcelona

18. Torroba Balmori, Mª Blanca. The Multiple Tasks Endured by PI3K during neural tube development.

Degree: 2016, Universitat de Barcelona

URL: http://hdl.handle.net/10803/399595

► El desarrollo de la médula espinal requiere una fina coordinación entre señales extracelulares y la activación de vías intracelulares específicas. De este modo se da… (more)

▼ El desarrollo de la médula espinal requiere una fina coordinación entre señales extracelulares y la activación de vías intracelulares específicas. De este modo se da una primera fase de proliferación de las células neuroepiteliales en la zona apical para aumentar el número de progenitores y una segunda fase de neurogénesis, a partir de la cual se originan diferentes tipos de neuronas. La clase IA de las PI3Ks se encuentra implicada en la transducción de señales a través de receptores tirosina quinasa (RTKs) o receptores acoplados a proteínas G (GPCRs). En respuesta a estímulos extracelulares, controlan la actividad de distintas proteínas diana a través de la producción local de lípidos PtdIns(3,4,5)P3. La clase IA de las PI3Ks, formada por enzimas heterodiméricas, consta de tres tipos de subunidades catalíticas (p110-alfa, p110-beta y p110-delta). Todas ellas son importantes para el desarrollo del sistema nervioso, sin embargo no están claras las funciones específicas de cada isoforma. El análisis de la expresión de PI3K a nivel de RNAm y proteína en la médula espinal embrionaria reveló una expresión diferencial según el estadío, siendo alta en progenitores antes de la neurogénesis y restringida a neuronas en estadíos más tardíos. Para estudiar su función en progenitores y neuronas, transfectamos formas activas de PI3K-alfa o suprimimos transitoriamente la p110-alfa en el tubo neural de embriones de pollo. La pérdida de p110-alfa provocó una alta tasa de apoptosis en ambas poblaciones, revelando su importancia en supervivencia. La sobreexpresión de la PI3K-alfa activa, en cambio, generó disrupciones muy severas del tejido neural caracterizadas por la presencia de masas celulares en la pared ventricular y mitosis ectópicas. En el lado basal, se observaron alteraciones en la laminación neuronal con células atravesando la lámina basal y crecimiento axonal aberrante. Nuestros resultados apuntan hacia la pérdida de polaridad como la principal causa de las aberraciones estructurales apicales, indicando que la PI3K-alfa tiene una función en la regulación de la polaridad apico basal. Asimismo, la PI3K-alfa parece implicada en la maduración del citoesqueleto neural y en el posicionamiento de las neuronas en el eje apico basal, funciones parcialmente mediadas por miembros de las Rho GTPasas. Advisors/Committee Members: Universitat de Barcelona. Facultat de Farmàcia, [email protected] (authoremail), false (authoremailshow), Pons Fuxá, Sebastián (director), Tauler Girona, Albert (tutor), true (authorsendemail).

Subjects/Keywords: Medul·la espinal; Médula espinal; Spinal cord; Neurobiologia del desenvolupament; Neurobiología del desarrollo; Developmental neurobiology; Ciències de la Salut; 576

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Torroba Balmori, M. B. (2016). The Multiple Tasks Endured by PI3K during neural tube development. (Thesis). Universitat de Barcelona. Retrieved from http://hdl.handle.net/10803/399595

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Torroba Balmori, Mª Blanca. “The Multiple Tasks Endured by PI3K during neural tube development.” 2016. Thesis, Universitat de Barcelona. Accessed January 22, 2021. http://hdl.handle.net/10803/399595.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Torroba Balmori, Mª Blanca. “The Multiple Tasks Endured by PI3K during neural tube development.” 2016. Web. 22 Jan 2021.

Vancouver:

Torroba Balmori MB. The Multiple Tasks Endured by PI3K during neural tube development. [Internet] [Thesis]. Universitat de Barcelona; 2016. [cited 2021 Jan 22]. Available from: http://hdl.handle.net/10803/399595.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Torroba Balmori MB. The Multiple Tasks Endured by PI3K during neural tube development. [Thesis]. Universitat de Barcelona; 2016. Available from: http://hdl.handle.net/10803/399595

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

19. Fuente Ruiz, Sandra de la. Development of new therapeutic strategies for Spinal Muscular Atrophy.

Degree: Departament de Medicina Experimental, 2020, Universitat de Lleida

URL: http://hdl.handle.net/10803/669753

► Spinal Muscular Atrophy (SMA) is a severe neurodegenerative disease and the first genetic cause of infant death. It is originated by the deletion or mutation… (more)

▼ Spinal Muscular Atrophy (SMA) is a severe neurodegenerative disease and the first genetic cause of infant death. It is originated by the deletion or mutation of Survival Motor Neuron 1 (SMN1) gene causing a Survival Motor Neuron (SMN) protein deficiency. The reduction of this protein predominantly leads to the degeneration of spinal cord motoneurons (MNs) and consequently produces skeletal muscle atrophy and weakness. The exact cellular and molecular mechanisms responsible for MN loss of function are only partially known. SMN reduction causes neurite degeneration and cell death without classical apoptotic features. Autophagy is an important and highly regulated process, essential for the removal of damaged organelles and toxic substances or proteins through lysosome degradation. This mechanism is specifically important in post-mitotic cells like MNs where autophagosome accumulation causes axonal transport disruption, interference of intracellular space trafficking, and neurite degeneration. What is well known in SMA is that intracellular SMN protein levels are critical to define the disease onset and severity, and this is partially determined by the number of copies of SMN2, the centromeric duplication of the SMN gene and the main modifier of SMA. For that reason, understanding the processes of SMN stability and degradation to identify compounds that increase protein levels is a major goal in SMA therapeutics development. Calpains are a family of calcium-dependent proteases that have been related to muscle disorders and neurodegenerative diseases. Specifically, it has been described in muscle that SMN can be a proteolytic target of calpain. Calpain activity is also involved in autophagy regulation by modulation of multiple proteins involved in the process. The objectives in the present work have been to analyze the autophagy deregulation and determine the involvement of calpain in SMN protein regulation on MNs, in order to deepen in the origin of neurodegeneration and to develop a new therapeutic approach for SMA disease. To this end, we have analyzed autophagic markers in different mouse and human SMA in vitro models. The results showed that autophagosomes and LC3 levels were increased in SMA samples compared to controls, suggesting a deregulation of the autophagy process throughout the disease progression. Moreover, calpain knockdown using an shRNA approach showed an increase of both, Smn and LC3 levels and prevented neurite degeneration occurred in SMA affected mouse MNs. Similar results were obtained in in vitro experiments using a pharmacological calpain inhibitor, calpeptin. Likewise, calpain activation produced by depolarized conditions induced α-fodrin and SMN proteolysis, confirming that calpain directly regulates the SMN protein level in MNs. Additionally, calpeptin in vivo treatment significantly improved the lifespan and motor function of two severe SMA mouse models, demonstrating the potential utility of calpain inhibitors in SMA therapeutics. Finally, the analysis of calpain pathway members in mice… Advisors/Committee Members: false (authoremailshow), Soler i Tatché, Rosa Ma. (director).

Subjects/Keywords: Atròfia Muscular Espinal; Motoneurones; Calpaina; Atrofia Muscular Espinal; Motoneuronas; Spinal Muscular Atrophy; Motoneurons; Calpain; Biologia Cel·lular; 576

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Fuente Ruiz, S. d. l. (2020). Development of new therapeutic strategies for Spinal Muscular Atrophy. (Thesis). Universitat de Lleida. Retrieved from http://hdl.handle.net/10803/669753

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Fuente Ruiz, Sandra de la. “Development of new therapeutic strategies for Spinal Muscular Atrophy.” 2020. Thesis, Universitat de Lleida. Accessed January 22, 2021. http://hdl.handle.net/10803/669753.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Fuente Ruiz, Sandra de la. “Development of new therapeutic strategies for Spinal Muscular Atrophy.” 2020. Web. 22 Jan 2021.

Vancouver:

Fuente Ruiz Sdl. Development of new therapeutic strategies for Spinal Muscular Atrophy. [Internet] [Thesis]. Universitat de Lleida; 2020. [cited 2021 Jan 22]. Available from: http://hdl.handle.net/10803/669753.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Fuente Ruiz Sdl. Development of new therapeutic strategies for Spinal Muscular Atrophy. [Thesis]. Universitat de Lleida; 2020. Available from: http://hdl.handle.net/10803/669753

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

20. FONTANA, João Vitor Nogueira. Non-newtonian fluids in a Hele-Shaw cell: a pattern formation study .

Degree: 2014, Universidade Federal de Pernambuco

URL: http://repositorio.ufpe.br/handle/123456789/13861

► A instabilidade de Saffman-Taylor se dá na interface entre dois fluidos viscosos no interior de uma célula de Hele-Shaw (CHS). A CHS é um aparato… (more)

Subjects/Keywords: Célula de Hele-Shaw; fluido não newtoniano; fluido yield stress; fluido power-law; competição de dedos viscosos; side branching

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APA (6^th Edition):

FONTANA, J. V. N. (2014). Non-newtonian fluids in a Hele-Shaw cell: a pattern formation study . (Thesis). Universidade Federal de Pernambuco. Retrieved from http://repositorio.ufpe.br/handle/123456789/13861

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

FONTANA, João Vitor Nogueira. “Non-newtonian fluids in a Hele-Shaw cell: a pattern formation study .” 2014. Thesis, Universidade Federal de Pernambuco. Accessed January 22, 2021. http://repositorio.ufpe.br/handle/123456789/13861.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

FONTANA, João Vitor Nogueira. “Non-newtonian fluids in a Hele-Shaw cell: a pattern formation study .” 2014. Web. 22 Jan 2021.

Vancouver:

FONTANA JVN. Non-newtonian fluids in a Hele-Shaw cell: a pattern formation study . [Internet] [Thesis]. Universidade Federal de Pernambuco; 2014. [cited 2021 Jan 22]. Available from: http://repositorio.ufpe.br/handle/123456789/13861.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

FONTANA JVN. Non-newtonian fluids in a Hele-Shaw cell: a pattern formation study . [Thesis]. Universidade Federal de Pernambuco; 2014. Available from: http://repositorio.ufpe.br/handle/123456789/13861

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

21. Roberto Lima da Costa Cisne JÃnior. Transporte de Fluidos e PartÃculas em Meios Irregulares.

Degree: PhD, 2014, Universidade Federal do Ceará

URL: http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=13645 ;

► O escoamento de fluidos no interior de estruturas irregulares apresenta certa complexidade. De inÃcio, investigamos o transporte de partÃculas no interior de uma estrutura ramificada… (more)

Subjects/Keywords: FISICA DA MATERIA CONDENSADA; escoamento; fluido; particulas

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APA (6^th Edition):

JÃnior, R. L. d. C. C. (2014). Transporte de Fluidos e PartÃculas em Meios Irregulares. (Doctoral Dissertation). Universidade Federal do Ceará. Retrieved from http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=13645 ;

Chicago Manual of Style (16^th Edition):

JÃnior, Roberto Lima da Costa Cisne. “Transporte de Fluidos e PartÃculas em Meios Irregulares.” 2014. Doctoral Dissertation, Universidade Federal do Ceará. Accessed January 22, 2021. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=13645 ;.

MLA Handbook (7^th Edition):

JÃnior, Roberto Lima da Costa Cisne. “Transporte de Fluidos e PartÃculas em Meios Irregulares.” 2014. Web. 22 Jan 2021.

Vancouver:

JÃnior RLdCC. Transporte de Fluidos e PartÃculas em Meios Irregulares. [Internet] [Doctoral dissertation]. Universidade Federal do Ceará 2014. [cited 2021 Jan 22]. Available from: http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=13645 ;.

Council of Science Editors:

JÃnior RLdCC. Transporte de Fluidos e PartÃculas em Meios Irregulares. [Doctoral Dissertation]. Universidade Federal do Ceará 2014. Available from: http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=13645 ;

22. SANTOS, Eduardo Gonçalves dos. Soluções fracas para fluidos assimétricos incompressíveis com densidade variável .

Degree: 2009, Universidade Federal de Pernambuco

URL: http://repositorio.ufpe.br/handle/123456789/13962

► Estudamos a existência de solução fraca global e local no tempo para o sistema que descreve o fluxo de um fluido assimetrico incompressível com densidade… (more)

Subjects/Keywords: Solução fraca; Fluido assimetrico; Dominio ilimitado

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APA (6^th Edition):

SANTOS, E. G. d. (2009). Soluções fracas para fluidos assimétricos incompressíveis com densidade variável . (Thesis). Universidade Federal de Pernambuco. Retrieved from http://repositorio.ufpe.br/handle/123456789/13962

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

SANTOS, Eduardo Gonçalves dos. “Soluções fracas para fluidos assimétricos incompressíveis com densidade variável .” 2009. Thesis, Universidade Federal de Pernambuco. Accessed January 22, 2021. http://repositorio.ufpe.br/handle/123456789/13962.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

SANTOS, Eduardo Gonçalves dos. “Soluções fracas para fluidos assimétricos incompressíveis com densidade variável .” 2009. Web. 22 Jan 2021.

Vancouver:

SANTOS EGd. Soluções fracas para fluidos assimétricos incompressíveis com densidade variável . [Internet] [Thesis]. Universidade Federal de Pernambuco; 2009. [cited 2021 Jan 22]. Available from: http://repositorio.ufpe.br/handle/123456789/13962.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

SANTOS EGd. Soluções fracas para fluidos assimétricos incompressíveis com densidade variável . [Thesis]. Universidade Federal de Pernambuco; 2009. Available from: http://repositorio.ufpe.br/handle/123456789/13962

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade do Rio Grande do Norte

23. Ribeiro, Laís Sibaldo. Uso de água produzida na formulação de fluidos de perfuração .

Degree: 2015, Universidade do Rio Grande do Norte

URL: http://repositorio.ufrn.br/handle/123456789/19778

► Drilling fluids have fundamental importance in the petroleum activities, since they are responsible for remove the cuttings, maintain pressure and well stability, preventing collapse and… (more)

▼ Drilling fluids have fundamental importance in the petroleum activities, since they are responsible for remove the cuttings, maintain pressure and well stability, preventing collapse and inflow of fluid into the rock formation and maintain lubrication and cooling the drill. There are basically three types of drilling fluids: water-based, non-aqueous and aerated based. The water-based drilling fluid is widely used because it is less aggressive to the environment and provide excellent stability and inhibition (when the water based drilling fluid is a inhibition fluid), among other qualities. Produced water is generated simultaneously with oil during production and has high concentrations of metals and contaminants, so it’s necessary to treat for disposal this water. The produced water from the fields of Urucu-AM and Riacho da forquilha-RN have high concentrations of contaminants, metals and salts such as calcium and magnesium, complicating their treatment and disposal. Thus, the objective was to analyze the use of synthetic produced water with similar characteristics of produced water from Urucu-AM and Riacho da Forquilha-RN for formulate a water-based drilling mud, noting the influence of varying the concentration of calcium and magnesium into filtered and rheology tests. We conducted a simple 32 factorial experimental design for statistical modeling of data. The results showed that the varying concentrations of calcium and magnesium did not influence the rheology of the fluid, where in the plastic viscosity, apparent viscosity and the initial and final gels does not varied significantly. For the filtrate tests, calcium concentration in a linear fashion influenced chloride concentration, where when we have a higher concentration of calcium we have a higher the concentration of chloride in the filtrate. For the Urucu’s produced water based fluids, volume of filtrate was observed that the calcium concentration influences quadratically, this means that high calcium concentrations interfere with the power of the inhibitors used in the formulation of the filtered fluid. For Riacho’s produced water based fluid, Calcium’s influences is linear for volume of filtrate. The magnesium concentration was significant only for chloride concentration in a quadratic way just for Urucu’s produced water based fluids. The mud with maximum concentration of magnesium (9,411g/L), but minimal concentration of calcium (0,733g/L) showed good results. Therefore, a maximum water produced by magnesium concentration of 9,411g/L and the maximum calcium concentration of 0,733g/L can be used for formulating water-based drilling fluids, providing appropriate properties for this kind of fluid. Advisors/Committee Members: Dantas, Tereza Neuma de Castro (advisor), 07286937391 (advisor), http://lattes.cnpq.br/0676872399141537 (advisor).

Subjects/Keywords: Fluido de perfuração; Água produzida; Reologia; Filtrado

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ribeiro, L. S. (2015). Uso de água produzida na formulação de fluidos de perfuração . (Thesis). Universidade do Rio Grande do Norte. Retrieved from http://repositorio.ufrn.br/handle/123456789/19778

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ribeiro, Laís Sibaldo. “Uso de água produzida na formulação de fluidos de perfuração .” 2015. Thesis, Universidade do Rio Grande do Norte. Accessed January 22, 2021. http://repositorio.ufrn.br/handle/123456789/19778.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ribeiro, Laís Sibaldo. “Uso de água produzida na formulação de fluidos de perfuração .” 2015. Web. 22 Jan 2021.

Vancouver:

Ribeiro LS. Uso de água produzida na formulação de fluidos de perfuração . [Internet] [Thesis]. Universidade do Rio Grande do Norte; 2015. [cited 2021 Jan 22]. Available from: http://repositorio.ufrn.br/handle/123456789/19778.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ribeiro LS. Uso de água produzida na formulação de fluidos de perfuração . [Thesis]. Universidade do Rio Grande do Norte; 2015. Available from: http://repositorio.ufrn.br/handle/123456789/19778

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade do Rio Grande do Norte

24. Alves, Nário Cézar Câmara. Recuperação de fluido de perfuração não aquoso utilizando sistemas microemulsionados .

Degree: 2016, Universidade do Rio Grande do Norte

URL: http://repositorio.ufrn.br/handle/123456789/23698

► There are two research fields essential for the oil market: cost optimization and environmental issues. In the well drilling operations the fluid system is shown… (more)

Subjects/Keywords: Fluido de perfuração; Microemulsão; Recuperação desemulsificantes tensoativos

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Alves, N. C. C. (2016). Recuperação de fluido de perfuração não aquoso utilizando sistemas microemulsionados . (Masters Thesis). Universidade do Rio Grande do Norte. Retrieved from http://repositorio.ufrn.br/handle/123456789/23698

Chicago Manual of Style (16^th Edition):

Alves, Nário Cézar Câmara. “Recuperação de fluido de perfuração não aquoso utilizando sistemas microemulsionados .” 2016. Masters Thesis, Universidade do Rio Grande do Norte. Accessed January 22, 2021. http://repositorio.ufrn.br/handle/123456789/23698.

MLA Handbook (7^th Edition):

Alves, Nário Cézar Câmara. “Recuperação de fluido de perfuração não aquoso utilizando sistemas microemulsionados .” 2016. Web. 22 Jan 2021.

Vancouver:

Alves NCC. Recuperação de fluido de perfuração não aquoso utilizando sistemas microemulsionados . [Internet] [Masters thesis]. Universidade do Rio Grande do Norte; 2016. [cited 2021 Jan 22]. Available from: http://repositorio.ufrn.br/handle/123456789/23698.

Council of Science Editors:

Alves NCC. Recuperação de fluido de perfuração não aquoso utilizando sistemas microemulsionados . [Masters Thesis]. Universidade do Rio Grande do Norte; 2016. Available from: http://repositorio.ufrn.br/handle/123456789/23698

Universidade do Rio Grande do Norte

25. Ribeiro, Laís Sibaldo. Uso de água produzida na formulação de fluidos de perfuração .

Degree: 2015, Universidade do Rio Grande do Norte

URL: http://repositorio.ufrn.br/handle/123456789/19778

► Drilling fluids have fundamental importance in the petroleum activities, since they are responsible for remove the cuttings, maintain pressure and well stability, preventing collapse and… (more)

▼ Drilling fluids have fundamental importance in the petroleum activities, since they are responsible for remove the cuttings, maintain pressure and well stability, preventing collapse and inflow of fluid into the rock formation and maintain lubrication and cooling the drill. There are basically three types of drilling fluids: water-based, non-aqueous and aerated based. The water-based drilling fluid is widely used because it is less aggressive to the environment and provide excellent stability and inhibition (when the water based drilling fluid is a inhibition fluid), among other qualities. Produced water is generated simultaneously with oil during production and has high concentrations of metals and contaminants, so it’s necessary to treat for disposal this water. The produced water from the fields of Urucu-AM and Riacho da forquilha-RN have high concentrations of contaminants, metals and salts such as calcium and magnesium, complicating their treatment and disposal. Thus, the objective was to analyze the use of synthetic produced water with similar characteristics of produced water from Urucu-AM and Riacho da Forquilha-RN for formulate a water-based drilling mud, noting the influence of varying the concentration of calcium and magnesium into filtered and rheology tests. We conducted a simple 32 factorial experimental design for statistical modeling of data. The results showed that the varying concentrations of calcium and magnesium did not influence the rheology of the fluid, where in the plastic viscosity, apparent viscosity and the initial and final gels does not varied significantly. For the filtrate tests, calcium concentration in a linear fashion influenced chloride concentration, where when we have a higher concentration of calcium we have a higher the concentration of chloride in the filtrate. For the Urucu’s produced water based fluids, volume of filtrate was observed that the calcium concentration influences quadratically, this means that high calcium concentrations interfere with the power of the inhibitors used in the formulation of the filtered fluid. For Riacho’s produced water based fluid, Calcium’s influences is linear for volume of filtrate. The magnesium concentration was significant only for chloride concentration in a quadratic way just for Urucu’s produced water based fluids. The mud with maximum concentration of magnesium (9,411g/L), but minimal concentration of calcium (0,733g/L) showed good results. Therefore, a maximum water produced by magnesium concentration of 9,411g/L and the maximum calcium concentration of 0,733g/L can be used for formulating water-based drilling fluids, providing appropriate properties for this kind of fluid. Advisors/Committee Members: Dantas, Tereza Neuma de Castro (advisor), 07286937391 (advisor), http://lattes.cnpq.br/0676872399141537 (advisor).

Subjects/Keywords: Fluido de perfuração; Água produzida; Reologia; Filtrado

Record Details Similar Records Cite « Share

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ribeiro, L. S. (2015). Uso de água produzida na formulação de fluidos de perfuração . (Masters Thesis). Universidade do Rio Grande do Norte. Retrieved from http://repositorio.ufrn.br/handle/123456789/19778

Chicago Manual of Style (16^th Edition):

Ribeiro, Laís Sibaldo. “Uso de água produzida na formulação de fluidos de perfuração .” 2015. Masters Thesis, Universidade do Rio Grande do Norte. Accessed January 22, 2021. http://repositorio.ufrn.br/handle/123456789/19778.

MLA Handbook (7^th Edition):

Ribeiro, Laís Sibaldo. “Uso de água produzida na formulação de fluidos de perfuração .” 2015. Web. 22 Jan 2021.

Vancouver:

Ribeiro LS. Uso de água produzida na formulação de fluidos de perfuração . [Internet] [Masters thesis]. Universidade do Rio Grande do Norte; 2015. [cited 2021 Jan 22]. Available from: http://repositorio.ufrn.br/handle/123456789/19778.

Council of Science Editors:

Ribeiro LS. Uso de água produzida na formulação de fluidos de perfuração . [Masters Thesis]. Universidade do Rio Grande do Norte; 2015. Available from: http://repositorio.ufrn.br/handle/123456789/19778

Università degli Studi di Bergamo

26. FONTANETO, FABRIZIO. Aero-thermal performance of a film-cooled high pressure turbine blade/vane: a test case for numerical codes validation.

Degree: 2014, Università degli Studi di Bergamo

URL: http://hdl.handle.net/10446/30755

► The present thesis concentrates on the experimental activity carried in the frame of two different measurement campaigns aiming to create an experimental test-case for turbomachinery… (more)

▼ The present thesis concentrates on the experimental activity carried in the frame of two different measurement campaigns aiming to create an experimental test-case for turbomachinery codes validation. The first experimental activity was carried out at the University of Bergamo and dealt with the characterization of the aero-thermal performance of a film-cooled high pressure turbine rotor blade. Aerodynamic measurements, performed by means of a 5-hole miniaturized pressure probe, evidenced a marked asymmetry of the secondary flows between the upper and the lower semi-channels. Injection seemed not to affect at all the secondary flows pattern: at every injection rate, the cooling jets kept attached to the endwall surface and confined in the boundary layer. Such a result was confirmed by the adiabatic effectiveness distribution which was retrieved by thermochromic liquid crystals. The high performance of the cooling system had to be related to the extreme tangential arrangement of the holes. The second measurement campaign was held at the von Karman Institute for Fluid Dynamics (VKI) (Belgium). A film-cooled transonic turbine vane was investigated in a five blades linear cascade configuration and at engine-like conditions. The inlet free-stream turbulence was fully characterized by means of hot-wire anemometry. The aerodynamic performance of the cascade was assessed by traversing a 3-hole pressure probe in the downstream section. Injection was found to slightly enhance total pressure wakes. Thin-film thermometers have been used to retrieve the blade convective heat transfer coefficient (h) distribution. The non-cooled tests demonstrated that the tripping effect of the film-cooling holes is the responsible for a transition of the boundary layer. The thermal protection of the suction side always increases with the injection rate while the pressure side is showing values of h higher than those of the non-cooled case: at low injection rates, the breaks down the boundary layer.

Subjects/Keywords: ING-IND/08 - Macchine a Fluido

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

FONTANETO, F. (2014). Aero-thermal performance of a film-cooled high pressure turbine blade/vane: a test case for numerical codes validation. (Thesis). Università degli Studi di Bergamo. Retrieved from http://hdl.handle.net/10446/30755

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

FONTANETO, FABRIZIO. “Aero-thermal performance of a film-cooled high pressure turbine blade/vane: a test case for numerical codes validation.” 2014. Thesis, Università degli Studi di Bergamo. Accessed January 22, 2021. http://hdl.handle.net/10446/30755.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

FONTANETO, FABRIZIO. “Aero-thermal performance of a film-cooled high pressure turbine blade/vane: a test case for numerical codes validation.” 2014. Web. 22 Jan 2021.

Vancouver:

FONTANETO F. Aero-thermal performance of a film-cooled high pressure turbine blade/vane: a test case for numerical codes validation. [Internet] [Thesis]. Università degli Studi di Bergamo; 2014. [cited 2021 Jan 22]. Available from: http://hdl.handle.net/10446/30755.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

FONTANETO F. Aero-thermal performance of a film-cooled high pressure turbine blade/vane: a test case for numerical codes validation. [Thesis]. Università degli Studi di Bergamo; 2014. Available from: http://hdl.handle.net/10446/30755

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Università di Cagliari

27. Sanna, Alessandro. Design and implementation of a computational environment for high performance scientific computing .

Degree: 2012, Università di Cagliari

URL: http://veprints.unica.it/690/

► This thesis has a three-fold aim. The first one regards the design and implementation of a multiphysics framework for high-performance scientific and engineering computing. The… (more)

Subjects/Keywords: ING-IND/08 Macchine a fluido

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sanna, A. (2012). Design and implementation of a computational environment for high performance scientific computing . (Thesis). Università di Cagliari. Retrieved from http://veprints.unica.it/690/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sanna, Alessandro. “Design and implementation of a computational environment for high performance scientific computing .” 2012. Thesis, Università di Cagliari. Accessed January 22, 2021. http://veprints.unica.it/690/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sanna, Alessandro. “Design and implementation of a computational environment for high performance scientific computing .” 2012. Web. 22 Jan 2021.

Vancouver:

Sanna A. Design and implementation of a computational environment for high performance scientific computing . [Internet] [Thesis]. Università di Cagliari; 2012. [cited 2021 Jan 22]. Available from: http://veprints.unica.it/690/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sanna A. Design and implementation of a computational environment for high performance scientific computing . [Thesis]. Università di Cagliari; 2012. Available from: http://veprints.unica.it/690/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Università degli Studi di Padova

28. Pezzuolo, Alex. Ottimizzazione e analisi in regime dinamico di un ciclo ORC cogenerativo.

Degree: 2015, Università degli Studi di Padova

URL: http://tesi.cab.unipd.it/48142/1/tesi_Pezzuolo_Alex.pdf

► Lo scopo della tesi è di creare un programma di ottimizzazione che, date alcune specifiche d'input, ricerchi il ciclo ORC e il fluido di lavoro… (more)

Subjects/Keywords: ING-IND/08 Macchine a fluido

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Pezzuolo, A. (2015). Ottimizzazione e analisi in regime dinamico di un ciclo ORC cogenerativo. (Thesis). Università degli Studi di Padova. Retrieved from http://tesi.cab.unipd.it/48142/1/tesi_Pezzuolo_Alex.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Pezzuolo, Alex. “Ottimizzazione e analisi in regime dinamico di un ciclo ORC cogenerativo.” 2015. Thesis, Università degli Studi di Padova. Accessed January 22, 2021. http://tesi.cab.unipd.it/48142/1/tesi_Pezzuolo_Alex.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Pezzuolo, Alex. “Ottimizzazione e analisi in regime dinamico di un ciclo ORC cogenerativo.” 2015. Web. 22 Jan 2021.

Vancouver:

Pezzuolo A. Ottimizzazione e analisi in regime dinamico di un ciclo ORC cogenerativo. [Internet] [Thesis]. Università degli Studi di Padova; 2015. [cited 2021 Jan 22]. Available from: http://tesi.cab.unipd.it/48142/1/tesi_Pezzuolo_Alex.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Pezzuolo A. Ottimizzazione e analisi in regime dinamico di un ciclo ORC cogenerativo. [Thesis]. Università degli Studi di Padova; 2015. Available from: http://tesi.cab.unipd.it/48142/1/tesi_Pezzuolo_Alex.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Università degli Studi di Padova

29. Pellegrino, Marco. CFD analysis of optimized configuration of a tiltrotor at full scale conditions including rotor effects.

Degree: 2015, Università degli Studi di Padova

URL: http://tesi.cab.unipd.it/48151/1/TesiMagistrale_Pellegrino.pdf

The thesis presents the outcomes of CFD simulations on the ERICA tiltrotor at full scale conditions including rotor effects. The purpose is to investigate the benefit of the optimised parts on the overall drag reduction

Subjects/Keywords: ING-IND/08 Macchine a fluido

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Pellegrino, M. (2015). CFD analysis of optimized configuration of a tiltrotor at full scale conditions including rotor effects. (Thesis). Università degli Studi di Padova. Retrieved from http://tesi.cab.unipd.it/48151/1/TesiMagistrale_Pellegrino.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Pellegrino, Marco. “CFD analysis of optimized configuration of a tiltrotor at full scale conditions including rotor effects.” 2015. Thesis, Università degli Studi di Padova. Accessed January 22, 2021. http://tesi.cab.unipd.it/48151/1/TesiMagistrale_Pellegrino.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Pellegrino, Marco. “CFD analysis of optimized configuration of a tiltrotor at full scale conditions including rotor effects.” 2015. Web. 22 Jan 2021.

Vancouver:

Pellegrino M. CFD analysis of optimized configuration of a tiltrotor at full scale conditions including rotor effects. [Internet] [Thesis]. Università degli Studi di Padova; 2015. [cited 2021 Jan 22]. Available from: http://tesi.cab.unipd.it/48151/1/TesiMagistrale_Pellegrino.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Pellegrino M. CFD analysis of optimized configuration of a tiltrotor at full scale conditions including rotor effects. [Thesis]. Università degli Studi di Padova; 2015. Available from: http://tesi.cab.unipd.it/48151/1/TesiMagistrale_Pellegrino.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Università degli Studi di Padova

30. Baldasso, Enrico. Performance analysis of Organic rankine cycles using multi-component working fluids.

Degree: 2015, Università degli Studi di Padova

URL: http://tesi.cab.unipd.it/48157/1/Enrico_Baldasso_Tesi_Magistrale.pdf

La tesi analizza l'utilizzo di miscele in impianti solari a concentrazione al fine di comprendere se è possibile ottenere efficienze superiori rispetto al caso di fluidi puri. L'analisi considera sia le condizioni di funzionamento nominale, che le condizioni di fuori progetto

Subjects/Keywords: ING-IND/08 Macchine a fluido

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Baldasso, E. (2015). Performance analysis of Organic rankine cycles using multi-component working fluids. (Thesis). Università degli Studi di Padova. Retrieved from http://tesi.cab.unipd.it/48157/1/Enrico_Baldasso_Tesi_Magistrale.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Baldasso, Enrico. “Performance analysis of Organic rankine cycles using multi-component working fluids.” 2015. Thesis, Università degli Studi di Padova. Accessed January 22, 2021. http://tesi.cab.unipd.it/48157/1/Enrico_Baldasso_Tesi_Magistrale.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Baldasso, Enrico. “Performance analysis of Organic rankine cycles using multi-component working fluids.” 2015. Web. 22 Jan 2021.

Vancouver:

Baldasso E. Performance analysis of Organic rankine cycles using multi-component working fluids. [Internet] [Thesis]. Università degli Studi di Padova; 2015. [cited 2021 Jan 22]. Available from: http://tesi.cab.unipd.it/48157/1/Enrico_Baldasso_Tesi_Magistrale.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Baldasso E. Performance analysis of Organic rankine cycles using multi-component working fluids. [Thesis]. Università degli Studi di Padova; 2015. Available from: http://tesi.cab.unipd.it/48157/1/Enrico_Baldasso_Tesi_Magistrale.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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