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1. Bortolli, Juliane de Quadros de. Efeito da aplica??o t?pica do extrato de camomila e da curcumina em ?lceras traum?ticas em l?ngua de ratos : an?lise cl?nica e histol?gica.

Degree: 2018, Pontifical Catholic University of Rio Grande do Sul

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Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES

The oral mucosa is a frequent site for traumatic ulcers, which can be caused by mechanical or chemical agents. There is no a gold standard treatment for the management of these lesions, which can be painful and have a negative impact on quality of life. Although studies suggest the use of chamomile and curcumin in the treatment of ulcerated lesions of the oral mucosa, there is no a consensus as to its efficacy in the management of these lesions. The literature has shown that both phytotherapics modulate the levels of inflammatory cytokines such as TNF-? and IL-1?. Therefore, in the first article of this dissertation, an integrative literature review was conducted investigating the efficacy of topical interventions with chamomile and curcumin in the management of pain and in the healing of ulcerated lesions of the oral mucosa. Few controlled clinical trials have been found and they suggest a beneficial effect of chamomile and curcumin in the healing process and in the reduction of symptoms in patients with oral mucositis, recurrent aphthous ulceration and oral lichen planus. Studies in animal demonstrated a reduction in the inflammatory wound healing phase, increased deposition of collagen fibers and epithelization. The second article of this dissertation presents an experimental study, which was carried out to evaluate the effect of the 10% chamomile extract and 2% curcumin in the repair of traumatic ulcers on tongue of rats. Thirty-nine Wistar rats were divided into three groups: control, chamomile extract and curcumin. A 5-mm-diameter excisional wound was made in the center of ventral tongue. The substances were applied as a gel twice daily for five days. The animals were euthanized 7 days after the lesions were made. In the macroscopic evaluation, there was no significant difference among chamomile, curcumin and control groups regarding to area of residual ulcer (P= 0.20). Histological analysis also showed no difference among the groups regarding newly formed epithelium area (P=0.97) or intensity of inflammatory infiltrate (P=0.72). Considering the experimental model, the findings of the present study showed that 10% chamomile extract and 2% curcumin did not accelerate the repair of traumatic oral ulcers or reduced the intensity of the inflammatory infiltrate, contradicting previous findings in the…

Advisors/Committee Members: Salum, Fernanda Gon?alves.

Subjects/Keywords: Extrato de Camomila; Curcumina; Cicatriza??o; ?lceras Orais; Fitoter?picos; Chamomile Extract; Curcumin; Wound Healing; Oral Ulcer; Natural Compounds; CIENCIAS DA SAUDE::ODONTOLOGIA

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APA (6th Edition):

Bortolli, J. d. Q. d. (2018). Efeito da aplica??o t?pica do extrato de camomila e da curcumina em ?lceras traum?ticas em l?ngua de ratos : an?lise cl?nica e histol?gica. (Masters Thesis). Pontifical Catholic University of Rio Grande do Sul. Retrieved from http://tede2.pucrs.br/tede2/handle/tede/8188

Chicago Manual of Style (16th Edition):

Bortolli, Juliane de Quadros de. “Efeito da aplica??o t?pica do extrato de camomila e da curcumina em ?lceras traum?ticas em l?ngua de ratos : an?lise cl?nica e histol?gica.” 2018. Masters Thesis, Pontifical Catholic University of Rio Grande do Sul. Accessed April 10, 2021. http://tede2.pucrs.br/tede2/handle/tede/8188.

MLA Handbook (7th Edition):

Bortolli, Juliane de Quadros de. “Efeito da aplica??o t?pica do extrato de camomila e da curcumina em ?lceras traum?ticas em l?ngua de ratos : an?lise cl?nica e histol?gica.” 2018. Web. 10 Apr 2021.

Vancouver:

Bortolli JdQd. Efeito da aplica??o t?pica do extrato de camomila e da curcumina em ?lceras traum?ticas em l?ngua de ratos : an?lise cl?nica e histol?gica. [Internet] [Masters thesis]. Pontifical Catholic University of Rio Grande do Sul; 2018. [cited 2021 Apr 10]. Available from: http://tede2.pucrs.br/tede2/handle/tede/8188.

Council of Science Editors:

Bortolli JdQd. Efeito da aplica??o t?pica do extrato de camomila e da curcumina em ?lceras traum?ticas em l?ngua de ratos : an?lise cl?nica e histol?gica. [Masters Thesis]. Pontifical Catholic University of Rio Grande do Sul; 2018. Available from: http://tede2.pucrs.br/tede2/handle/tede/8188

2. Aleluia, Augusto Cezar Magalh??es. Determina????o de macro e microelementos em medicamentos fitoter??picos.

Degree: 2015, Instituto de Qu??mica; Programa de P??s Gradua????o em Qu??mica; IQ; brasil

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CNPq e CAPES

A utiliza????o de medicamentos fitoter??picos ?? global, ocorrendo em diferentes classes sociais. O uso de plantas para fins medicinais foi a base para a consolida????o da terap??utica utilizando fitoter??picos, os quais correspondem ??nica e exclusivamente a produtos fabricados a partir de mat??ria-prima vegetal. A qualidade de um medicamento ?? resultado de todo o processo para a sua obten????o, desde os componentes utilizados na formula????o at?? sua dispensa????o aos indiv??duos. Dentre as possibilidades de desvio da qualidade com ou sem comprometimento da sa??de humana destaca-se o teor de certos elementos qu??micos presentes nos produtos. O presente trabalho teve como objetivo determinar a partir de um m??todo validado os macroelementos Na, K, Ca, Mg e P e os microelementos Se e Zn em medicamentos fitoter??picos comercializados em farm??cias e drogarias da cidade de Salvador-Ba empregando espectrometria de emis??o ??ptica com plasma indutivamente acoplado (ICP OES) e analisar os dados obtidos por ferramentas de an??lise explorat??ria, an??lise de componentes principais (PCA) e an??lise de grupamentos hier??rquicos (HCA). Para valida????o do m??todo anal??tico proposto, foram analisados os par??metros estabelecidos pela IUPAC. A exatid??o do m??todo foi confirmada a partir da compara????o dos valores de concentra????o obtidos experimentalmente com os valores certificados em material de refer??ncia. A precis??o, expressa pelo desvio padr??o relativo (RSD), foi avaliada em duas amostras reais, variando entre 1,15 e 14,1%. Os limites de quantifica????o foram estabelecidos, sendo 0,0026; 0,0385; 0,0207; 0,0071; 0,0072; 0,0010 e 0,0009 mg g-1 para Na, K, Ca, Mg, P, Se e Zn, respectivamente, demonstrando a sensibilidade do m??todo. A partir das an??lises de PCA e HCA, foi observado a forma????o de grupos, o que permitiu a discrimina????o dos medicamentos pelas concentra????es dos analitos determinados. Avaliou-se o teor dos mesmos conforme posologia indicada em bul??rio, evidenciando altos valores de Na e Se em algumas amostras ?? luz das recomenda????es de ingest??o di??ria preconizadas pela Organiza????o Mundial da Sa??de (OMS) e Ag??ncia Nacional de Vigil??ncia Sanit??ria (ANVISA). O emprego de ferramentas quimiom??tricas demonstrou-se satisfat??rio e eficaz para avalia????o de macro e microelementos em amostras complexas.

Herbals medicines consume happens all over the world at different social…

Advisors/Committee Members: Ferreira, Sergio Luis Costa, Santos, Ana Maria Pinto dos, Silva, Lid??rcia Cavalcanti Ribeiro Cerqueira e.

Subjects/Keywords: Qu??mica Anal??tica; Fitoter??picos; Macroelementos; Microelementos; PCA; HCA; Ervas - Uso terap??utico; Produtos qu??micos - Efeitos fisiol??gico; Medicamentos - An??lise - Metais; Farm??cia - Comercio - Salvador(BA); An??lise espectral

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Aleluia, A. C. M. (2015). Determina????o de macro e microelementos em medicamentos fitoter??picos. (Masters Thesis). Instituto de Qu??mica; Programa de P??s Gradua????o em Qu??mica; IQ; brasil. Retrieved from http://repositorio.ufba.br/ri/handle/ri/19186

Chicago Manual of Style (16th Edition):

Aleluia, Augusto Cezar Magalh??es. “Determina????o de macro e microelementos em medicamentos fitoter??picos.” 2015. Masters Thesis, Instituto de Qu??mica; Programa de P??s Gradua????o em Qu??mica; IQ; brasil. Accessed April 10, 2021. http://repositorio.ufba.br/ri/handle/ri/19186.

MLA Handbook (7th Edition):

Aleluia, Augusto Cezar Magalh??es. “Determina????o de macro e microelementos em medicamentos fitoter??picos.” 2015. Web. 10 Apr 2021.

Vancouver:

Aleluia ACM. Determina????o de macro e microelementos em medicamentos fitoter??picos. [Internet] [Masters thesis]. Instituto de Qu??mica; Programa de P??s Gradua????o em Qu??mica; IQ; brasil; 2015. [cited 2021 Apr 10]. Available from: http://repositorio.ufba.br/ri/handle/ri/19186.

Council of Science Editors:

Aleluia ACM. Determina????o de macro e microelementos em medicamentos fitoter??picos. [Masters Thesis]. Instituto de Qu??mica; Programa de P??s Gradua????o em Qu??mica; IQ; brasil; 2015. Available from: http://repositorio.ufba.br/ri/handle/ri/19186

3. LEITE, Maria Rita de C?ssia. Perspectiva e potencialidades para cria??o de um curso de Mestrado em Plantas Medicinais e Fitoter?picos na Universidade Federal Rural do Rio de Janeiro - UFRRJ.

Degree: 2016, Universidade Federal Rural do Rio de Janeiro; Programa de P?s-Gradua??o em Educa??o Agr?cola; UFRRJ; Brasil; Instituto de Agronomia

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In all eras and culture, human being has learned to take advantage from local natural resources, including the use of medicinal plants. Therefore, phytotherapy has presented great potential for economic and social development, considering not only Brazilian plant diversity, as well as medicinal plants has closely been associated to popular culture. In the last 25 years, 77.8% of the anti-cancer agents tested becoming unquestionable their contribution to new drugs development (Nogueira et al, 2010). On the other hand, the University has been responsible for following reality and time, as well as generating knowledge and critical mass for transforming verities for the benefit of the society, training ethical and competent professionals and citizens committed to the well-being of present and future society. Need for Stricto Sensu Post Graduation course for professional generation in the quality processing, production and control from plant raw material to herbal products has been fundamental to understand the differences between the concept of phytotherapic as medicine and the use of medicinal plants in Integrative and Complementary Therapies, always observing the rational relevance of its use. Thus, this study aimed considering the UFRRJ potential by interdisciplinary and multiprofessional manner proposing the establishment of a Stricto Sensu Post Graduation course in phytotherapics and medicinal plants prioritizing the formation of human resources acting in whole productive chain from plant raw material harvested in the field and its processing to phytotherapic medicine industrial manufacture, as well as establishing criteria for the rational use of medicinal plants within the context of the Practices of Integrative and Complementary Actions of Health Ministry for health professionals besides complying with the National Policy Guidelines for Medicinal Plants and Phytotherapics. This qualitative, descriptive and exploratory research was carried out at Universidade Federal Rural do Rio de Janeiro (UFRRJ) in Serop?dica municipality-RJ. Data from January to July, 2016 were collected. Open unstructured interviews of participant observations by telephone and e-mail with professionals working in related areas were the instruments used. As a result, the UFRRJ, for its tradition in Agricultural Sciences teaching and research has presented in its Institutes, Departments, Disciplines, Laboratories and Research Groups all the potential and infrastructure for organizing and complying with the implementation of Phytotherapics and Medicinal Plants Stricto sensu Post Graduation course .

Em todas as ?pocas e culturas…

Advisors/Committee Members: Santos, Gabriel de Ara?jo, Santos, Gabriel de Ara?jo, Damasceno J?nior, Pedro Corr?a, Peregrino, Carlos Augusto de Freitas.

Subjects/Keywords: Medicinal plants; Legislation and Public Policy; Phytotherapics; Stricto Sensu Post Graduation; Technological innovation; Plantas Medicinais; Fitoter?picos; Legisla??o e Pol?ticas P?blicas; Inova??o Tecnol?gica; P?s-Gradua??o Stricto Sensu; Educa??o

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

LEITE, M. R. d. C. (2016). Perspectiva e potencialidades para cria??o de um curso de Mestrado em Plantas Medicinais e Fitoter?picos na Universidade Federal Rural do Rio de Janeiro - UFRRJ. (Masters Thesis). Universidade Federal Rural do Rio de Janeiro; Programa de P?s-Gradua??o em Educa??o Agr?cola; UFRRJ; Brasil; Instituto de Agronomia. Retrieved from https://tede.ufrrj.br/jspui/handle/jspui/2171

Chicago Manual of Style (16th Edition):

LEITE, Maria Rita de C?ssia. “Perspectiva e potencialidades para cria??o de um curso de Mestrado em Plantas Medicinais e Fitoter?picos na Universidade Federal Rural do Rio de Janeiro - UFRRJ.” 2016. Masters Thesis, Universidade Federal Rural do Rio de Janeiro; Programa de P?s-Gradua??o em Educa??o Agr?cola; UFRRJ; Brasil; Instituto de Agronomia. Accessed April 10, 2021. https://tede.ufrrj.br/jspui/handle/jspui/2171.

MLA Handbook (7th Edition):

LEITE, Maria Rita de C?ssia. “Perspectiva e potencialidades para cria??o de um curso de Mestrado em Plantas Medicinais e Fitoter?picos na Universidade Federal Rural do Rio de Janeiro - UFRRJ.” 2016. Web. 10 Apr 2021.

Vancouver:

LEITE MRdC. Perspectiva e potencialidades para cria??o de um curso de Mestrado em Plantas Medicinais e Fitoter?picos na Universidade Federal Rural do Rio de Janeiro - UFRRJ. [Internet] [Masters thesis]. Universidade Federal Rural do Rio de Janeiro; Programa de P?s-Gradua??o em Educa??o Agr?cola; UFRRJ; Brasil; Instituto de Agronomia; 2016. [cited 2021 Apr 10]. Available from: https://tede.ufrrj.br/jspui/handle/jspui/2171.

Council of Science Editors:

LEITE MRdC. Perspectiva e potencialidades para cria??o de um curso de Mestrado em Plantas Medicinais e Fitoter?picos na Universidade Federal Rural do Rio de Janeiro - UFRRJ. [Masters Thesis]. Universidade Federal Rural do Rio de Janeiro; Programa de P?s-Gradua??o em Educa??o Agr?cola; UFRRJ; Brasil; Instituto de Agronomia; 2016. Available from: https://tede.ufrrj.br/jspui/handle/jspui/2171

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