subject:(Fetus)

University of Manchester

1. Sibley, Colin. The nutrient exchange phenotype of the placenta in fetal growth restriction : characterization, adaptation and regulation.

Degree: Thesis (D.Sc.), 2013, University of Manchester

URL: https://www.research.manchester.ac.uk/portal/en/theses/the-nutrient-exchange-phenotype-of-the-placenta-in-fetalgrowth-restriction-characterization-adaptation-and-regulation(35a27da9-ad7c-4e7e-8e91-8742304a5c9c).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.588114

► An essential function of the placenta is the exchange of nutrients, and wasteproducts of fetal metabolism, between mother and fetus. The placenta thereforeplays a key… (more)

▼ An essential function of the placenta is the exchange of nutrients, and wasteproducts of fetal metabolism, between mother and fetus. The placenta thereforeplays a key role in determining fetal growth and size at birth. Fetal growthrestriction (FGR) is a complication affecting around 5% of pregnancies. Thereare several possible causes of FGR but the most common in the Western world isplacental dysfunction. The FGR baby is at much greater risk of stillbirth andneurodevelopmental morbidities than the normally grown baby. Furthermore, thesmaller baby per se has an increased risk of a range of morbidities as an adult.The thrust of the work covered in this thesis was to improve understanding of theabnormalities in placental exchange physiology associated with FGR. The goalwas (and is) to develop new placental diagnostic biomarkers for the disease andnew treatments based on improving placental function.The first tranche of work described showed that there are specific changes intransporter activities in the placenta in FGR. My colleagues and I showed thatSystem A amino acid transporter activity in the microvillous plasma membrane(MVM) of the syncytiotrophoblast (transporting epithelium of the placenta) isreduced, per mg membrane protein, and that this reduction is related to theseverity of the disease. This contrasted with our observation in normal pregnancythat MVM System A activity, per mg protein, is inversely related to size of the babyat birth, and first suggested the concept of placental adaptation to fetal growthdemand. We, and others, went on to show that a number of other transporters inthe syncytiotrophoblast are altered in FGR. However, not all transporters areaffected and at least one is upregulated. This led me to hypothesise that some ofthese changes are causal to FGR and some are responses, or adaptations, toabnormal fetal growth. The direct causes of transporter activity changes are notknown but our work, and that of others, suggests that glucocorticoids play a role.We also showed that transporter activities in the placenta are affected in othercomplications where fetal growth is aberrant. Furthermore, we provided evidencethat denuded areas of the syncytiotrophoblast might be the morphologicalcorrelate of a route of passive transfer of hydrophilic solutes across the placenta.Our studies in a mouse model of FGR suggest that abnormalities in such aparacellular route may be part of the placental dysfunction in the disease.In the final group of publications of this thesis I describe work showing gestationalchanges in placental transporter activities. I suggest that these are primarilyregulated to maintain fetal growth trajectory, but may also provide for specificnutrient demands at particular times in gestation. This explanation was supportedby work with genetically modified mice showing experimentally that placentaltransporter activity is regulated, or adapted, in relation to fetal growth demand. Itappears from several studies described here that there is a matching of fetalgrowth demand and placental nutrient…

Subjects/Keywords: 612.6; Placenta; Fetus

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APA (6^th Edition):

Sibley, C. (2013). The nutrient exchange phenotype of the placenta in fetal growth restriction : characterization, adaptation and regulation. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/the-nutrient-exchange-phenotype-of-the-placenta-in-fetalgrowth-restriction-characterization-adaptation-and-regulation(35a27da9-ad7c-4e7e-8e91-8742304a5c9c).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.588114

Chicago Manual of Style (16^th Edition):

Sibley, Colin. “The nutrient exchange phenotype of the placenta in fetal growth restriction : characterization, adaptation and regulation.” 2013. Doctoral Dissertation, University of Manchester. Accessed January 29, 2020. https://www.research.manchester.ac.uk/portal/en/theses/the-nutrient-exchange-phenotype-of-the-placenta-in-fetalgrowth-restriction-characterization-adaptation-and-regulation(35a27da9-ad7c-4e7e-8e91-8742304a5c9c).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.588114.

MLA Handbook (7^th Edition):

Sibley, Colin. “The nutrient exchange phenotype of the placenta in fetal growth restriction : characterization, adaptation and regulation.” 2013. Web. 29 Jan 2020.

Vancouver:

Sibley C. The nutrient exchange phenotype of the placenta in fetal growth restriction : characterization, adaptation and regulation. [Internet] [Doctoral dissertation]. University of Manchester; 2013. [cited 2020 Jan 29]. Available from: https://www.research.manchester.ac.uk/portal/en/theses/the-nutrient-exchange-phenotype-of-the-placenta-in-fetalgrowth-restriction-characterization-adaptation-and-regulation(35a27da9-ad7c-4e7e-8e91-8742304a5c9c).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.588114.

Council of Science Editors:

Sibley C. The nutrient exchange phenotype of the placenta in fetal growth restriction : characterization, adaptation and regulation. [Doctoral Dissertation]. University of Manchester; 2013. Available from: https://www.research.manchester.ac.uk/portal/en/theses/the-nutrient-exchange-phenotype-of-the-placenta-in-fetalgrowth-restriction-characterization-adaptation-and-regulation(35a27da9-ad7c-4e7e-8e91-8742304a5c9c).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.588114

University of Hawaii – Manoa

2. Montes, Ana Maria. Lung-derived growth factors : possible paracrine effectors of fetal lung development.

Degree: PhD, 2009, University of Hawaii – Manoa

URL: http://hdl.handle.net/10125/9418

►

Typescript.

Bibliography: leaves 103-111.

Photocopy.

Microfilm.

x, 111 leaves, bound ill. 29 cm

Morphogenesis involves the specific arrangement of embryonic cell populations which ultimately results… (more)

▼

Typescript.

Bibliography: leaves 103-111.

Photocopy.

Microfilm.

x, 111 leaves, bound ill. 29 cm

Morphogenesis involves the specific arrangement of embryonic cell populations which ultimately results in organs with unique structures. Substantial evidence suggests that cell and tissue interactions are the primary regulatory mechanisms for the developmental process. A potential role for paracrine secretions in lung organogenesis has been hypothesized (Alescio & Piperno, 1957). These studies present direct support for the paracrine model by demonstrating the presence of locally produced mitogenic/maturational factors in fetal rat lung tissue. Conditioned serum free medium (CSFM) from nineteen-day fetal rat lung cultures was shown to contain several bioactive peptides as detected by 3H-Thymidine incorporation into chick embryo and rat lung fibroblasts, as well as 14C-choline incorporation into surfactant in mixed cell cultures. Using ion-exchange chromatography and Sephadex gel filtration, a partially purified mitogen, 11-111, was obtained. Although II-III cross-reacts in the somatomedin-C (Sm-C) radioimmunoassay, disc polyacrylamide gel electrophoresis demonstrates that this component has an electrophoretic mobility [Rf value] of 0.59 (+/-0.02) and does not co-migrate with Sm-C in this system (Rf = 0.53 ) and, thus, is probably not authentic Sm-C. The partially purified II-III stimulates mitosis in chick embryo fibroblasts and post-natal rat lung fibroblasts. Multiplication in fetal rat lung fibroblast cultures is stimulated only when these are pre-incubated with a competence factor or unprocessed CSFM. This suggests the existence of an endogenously produced competence factor important in the regulation of fetal lung growth. Preparation II-III does not possess surfactant stimulating activity as assessed by 3H-choline incorporation into lipids in predominantly type-II cell cultures. However, a peak of surfactant stimulating activity was found to elute off Sephadex G-75 at a Kav = 0.23 (MW approx. 13 Kd) and was distinct from the mitogenic II-III peak (Kav = 0.50). These data demonstrate the presence of a maturational/ mitogenic factor, influencing type-II mixed cell cultures. In addition, II-III had been shown to play an autocrine role stimulating the proliferation of fetal lung fibroblasts. Finally, these data suggest the existance of a local produced competence factor.

Subjects/Keywords: Lungs – Growth; Fetus – Growth

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APA (6^th Edition):

Montes, A. M. (2009). Lung-derived growth factors : possible paracrine effectors of fetal lung development. (Doctoral Dissertation). University of Hawaii – Manoa. Retrieved from http://hdl.handle.net/10125/9418

Chicago Manual of Style (16^th Edition):

Montes, Ana Maria. “Lung-derived growth factors : possible paracrine effectors of fetal lung development.” 2009. Doctoral Dissertation, University of Hawaii – Manoa. Accessed January 29, 2020. http://hdl.handle.net/10125/9418.

MLA Handbook (7^th Edition):

Montes, Ana Maria. “Lung-derived growth factors : possible paracrine effectors of fetal lung development.” 2009. Web. 29 Jan 2020.

Vancouver:

Montes AM. Lung-derived growth factors : possible paracrine effectors of fetal lung development. [Internet] [Doctoral dissertation]. University of Hawaii – Manoa; 2009. [cited 2020 Jan 29]. Available from: http://hdl.handle.net/10125/9418.

Council of Science Editors:

Montes AM. Lung-derived growth factors : possible paracrine effectors of fetal lung development. [Doctoral Dissertation]. University of Hawaii – Manoa; 2009. Available from: http://hdl.handle.net/10125/9418

Montana State University

3. Alexander, James Kermott. The utilization of carbohydrate intermediates and amino acids by Vibrio Fetus.

Degree: College of Agriculture, 1954, Montana State University

URL: https://scholarworks.montana.edu/xmlui/handle/1/4737

Subjects/Keywords: Campylobacter fetus.

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APA (6^th Edition):

Alexander, J. K. (1954). The utilization of carbohydrate intermediates and amino acids by Vibrio Fetus. (Thesis). Montana State University. Retrieved from https://scholarworks.montana.edu/xmlui/handle/1/4737

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Alexander, James Kermott. “The utilization of carbohydrate intermediates and amino acids by Vibrio Fetus.” 1954. Thesis, Montana State University. Accessed January 29, 2020. https://scholarworks.montana.edu/xmlui/handle/1/4737.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Alexander, James Kermott. “The utilization of carbohydrate intermediates and amino acids by Vibrio Fetus.” 1954. Web. 29 Jan 2020.

Vancouver:

Alexander JK. The utilization of carbohydrate intermediates and amino acids by Vibrio Fetus. [Internet] [Thesis]. Montana State University; 1954. [cited 2020 Jan 29]. Available from: https://scholarworks.montana.edu/xmlui/handle/1/4737.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Alexander JK. The utilization of carbohydrate intermediates and amino acids by Vibrio Fetus. [Thesis]. Montana State University; 1954. Available from: https://scholarworks.montana.edu/xmlui/handle/1/4737

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Montana State University

4. May, Lewis K. The microaerophilic nature of Vibrio Fetus.

Degree: College of Agriculture, 1953, Montana State University

URL: https://scholarworks.montana.edu/xmlui/handle/1/5715

Subjects/Keywords: Campylobacter fetus.

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APA (6^th Edition):

May, L. K. (1953). The microaerophilic nature of Vibrio Fetus. (Thesis). Montana State University. Retrieved from https://scholarworks.montana.edu/xmlui/handle/1/5715

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

May, Lewis K. “The microaerophilic nature of Vibrio Fetus.” 1953. Thesis, Montana State University. Accessed January 29, 2020. https://scholarworks.montana.edu/xmlui/handle/1/5715.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

May, Lewis K. “The microaerophilic nature of Vibrio Fetus.” 1953. Web. 29 Jan 2020.

Vancouver:

May LK. The microaerophilic nature of Vibrio Fetus. [Internet] [Thesis]. Montana State University; 1953. [cited 2020 Jan 29]. Available from: https://scholarworks.montana.edu/xmlui/handle/1/5715.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

May LK. The microaerophilic nature of Vibrio Fetus. [Thesis]. Montana State University; 1953. Available from: https://scholarworks.montana.edu/xmlui/handle/1/5715

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Sydney

5. Walsh, Anna. The Legal Status of Prenatal Life in Australia .

Degree: 2015, University of Sydney

URL: http://hdl.handle.net/2123/14310

► This thesis is a doctrinal analysis of the legislation and case law in Australia regulating destruction of the fetus in the contexts of third party… (more)

Subjects/Keywords: fetus; abortion; conscientious objection

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APA (6^th Edition):

Walsh, A. (2015). The Legal Status of Prenatal Life in Australia . (Thesis). University of Sydney. Retrieved from http://hdl.handle.net/2123/14310

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Walsh, Anna. “The Legal Status of Prenatal Life in Australia .” 2015. Thesis, University of Sydney. Accessed January 29, 2020. http://hdl.handle.net/2123/14310.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Walsh, Anna. “The Legal Status of Prenatal Life in Australia .” 2015. Web. 29 Jan 2020.

Vancouver:

Walsh A. The Legal Status of Prenatal Life in Australia . [Internet] [Thesis]. University of Sydney; 2015. [cited 2020 Jan 29]. Available from: http://hdl.handle.net/2123/14310.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Walsh A. The Legal Status of Prenatal Life in Australia . [Thesis]. University of Sydney; 2015. Available from: http://hdl.handle.net/2123/14310

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Michigan State University

6. Sprague, James I., Jr. Growth and development of the swine fetus.

Degree: PhD, 1961, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:37603

Subjects/Keywords: Swine; Fetus

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APA (6^th Edition):

Sprague, James I., J. (1961). Growth and development of the swine fetus. (Doctoral Dissertation). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:37603

Chicago Manual of Style (16^th Edition):

Sprague, James I., Jr. “Growth and development of the swine fetus.” 1961. Doctoral Dissertation, Michigan State University. Accessed January 29, 2020. http://etd.lib.msu.edu/islandora/object/etd:37603.

MLA Handbook (7^th Edition):

Sprague, James I., Jr. “Growth and development of the swine fetus.” 1961. Web. 29 Jan 2020.

Vancouver:

Sprague, James I. J. Growth and development of the swine fetus. [Internet] [Doctoral dissertation]. Michigan State University; 1961. [cited 2020 Jan 29]. Available from: http://etd.lib.msu.edu/islandora/object/etd:37603.

Council of Science Editors:

Sprague, James I. J. Growth and development of the swine fetus. [Doctoral Dissertation]. Michigan State University; 1961. Available from: http://etd.lib.msu.edu/islandora/object/etd:37603

Universidade Federal de Santa Maria

7. Ana Cláudia Mello Groff. PCR PARA O DIAGNÓSTICO DA CAMPILOBACTERIOSE GENITAL BOVINA.

Degree: 2005, Universidade Federal de Santa Maria

URL: http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=1473

►

A campilobacteriose genital bovina, caracterizada principalmente por infertilidade, é uma doença de difícil diagnóstico, devido à natureza microaerófila do seu agente etiológico, o Campylobacter fetus,… (more)

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A campilobacteriose genital bovina, caracterizada principalmente por infertilidade, é uma doença de difícil diagnóstico, devido à natureza microaerófila do seu agente etiológico, o Campylobacter fetus, tendo assim sua prevalência subestimada. Este trabalho teve por objetivo avaliar a utilização da técnica de PCR para o diagnóstico da campilobacteriose genital bovina, utilizando amostras de aspirado prepucial, muco cervical e conteúdo abomasal de fetos abortados, coletadas em meio de transporte e enriquecimento; bem como comparar seu desempenho com a técnica do isolamento bacteriano. Foram testados cinco diferentes protocolos de extração de DNA de Campylobacter fetus: termo extração, lise com proteinase K, lise com isotiocianato de guanidina, lise com DNAzol? e lise com brometo de cetiltrimetilamônio (CTAB). Também foram avaliadas a especificidade, a sensibilidade e a aplicação da técnica da PCR em amostras clínicas. Os resultados indicaram que o CTAB foi o protocolo de extração mais eficiente; o par de primers utilizado mostrou-se específico; e o limite de detecção foi 63 unidades formadoras de colônias (UFC) de C. fetus. A PCR encontrou 24% (68/277) das amostras clínicas positivas para C. fetus, enquanto a cultura encontrou 2,8% (8/277). A técnica da PCR é específica e sensível, e mostra-se superior a cultura no diagnóstico da campilobacteriose genital bovina.

Bovine genital campylobacteriosis is a disease of difficult diagnostic because of the microaerophilic nature of its etiologic agent, Campylobacter fetus, thereby causing the prevalence related to this disease to be underestimated. The purpose of this study was to evaluate the utilization of PCR for the diagnosis of genital campylobacteriosis, using samples obtained from bull prepuce aspirate, cow cervical mucus, and abomasum contents obtained from aborted fetuses, collected in transport and enrichment medium. Five different DNA extraction protocols were tested: thermal extraction, lyses with proteinase K, lyses with guanidine isothiocyanate, lyses with DNAzol? , and lyses with CTAB. The specificity, sensitivity and technical application of PCR assay were also evaluated with clinical samples. The PCR performance was compared to the culture technique for bacterial isolation. The CTAB was the most efficient extraction protocol; the pair of primers used was shown to be specific; and the limit of detection was of 63 CFU of Campylobacter fetus. PCR demonstrated that 24% (68/277) of the clinical samples were positive for Campylobacter fetus, while only 2.8% (8/277) of samples were positive by culture techinque. These results indicate that the PCR technique is specific and sensitivy, and is superior to the culture for the diagnosis of bovine genital campylobacteriosis.

Advisors/Committee Members: Rudi Weiblen, Agueda Palmira Castagna de Vargas.

Subjects/Keywords: diagnóstico; campylobacter fetus; isolamento; MEDICINA VETERINARIA; campylobacter fetus; diagnostic; culture

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APA (6^th Edition):

Groff, A. C. M. (2005). PCR PARA O DIAGNÓSTICO DA CAMPILOBACTERIOSE GENITAL BOVINA. (Thesis). Universidade Federal de Santa Maria. Retrieved from http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=1473

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Groff, Ana Cláudia Mello. “PCR PARA O DIAGNÓSTICO DA CAMPILOBACTERIOSE GENITAL BOVINA.” 2005. Thesis, Universidade Federal de Santa Maria. Accessed January 29, 2020. http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=1473.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Groff, Ana Cláudia Mello. “PCR PARA O DIAGNÓSTICO DA CAMPILOBACTERIOSE GENITAL BOVINA.” 2005. Web. 29 Jan 2020.

Vancouver:

Groff ACM. PCR PARA O DIAGNÓSTICO DA CAMPILOBACTERIOSE GENITAL BOVINA. [Internet] [Thesis]. Universidade Federal de Santa Maria; 2005. [cited 2020 Jan 29]. Available from: http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=1473.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Groff ACM. PCR PARA O DIAGNÓSTICO DA CAMPILOBACTERIOSE GENITAL BOVINA. [Thesis]. Universidade Federal de Santa Maria; 2005. Available from: http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=1473

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Missouri – Columbia

8. Kirkpatrick, James R., 1983-. Examination of exogenous estrogenic chemical exposure and altered fetal nutrition in the CD-1 mouse fetus.

Degree: 2009, University of Missouri – Columbia

URL: http://hdl.handle.net/10355/9679

► My dissertation examines two issues related to disruption of fetal growth: exposure to exogenous estrogenic chemicals and altered nutrition. My first set of studies was… (more)

Subjects/Keywords: Fetus – Growth; Fetus – Nutrition; Estrogen – Toxicology; Mice – Pregnancy

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APA (6^th Edition):

Kirkpatrick, James R., 1. (2009). Examination of exogenous estrogenic chemical exposure and altered fetal nutrition in the CD-1 mouse fetus. (Thesis). University of Missouri – Columbia. Retrieved from http://hdl.handle.net/10355/9679

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kirkpatrick, James R., 1983-. “Examination of exogenous estrogenic chemical exposure and altered fetal nutrition in the CD-1 mouse fetus.” 2009. Thesis, University of Missouri – Columbia. Accessed January 29, 2020. http://hdl.handle.net/10355/9679.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kirkpatrick, James R., 1983-. “Examination of exogenous estrogenic chemical exposure and altered fetal nutrition in the CD-1 mouse fetus.” 2009. Web. 29 Jan 2020.

Vancouver:

Kirkpatrick, James R. 1. Examination of exogenous estrogenic chemical exposure and altered fetal nutrition in the CD-1 mouse fetus. [Internet] [Thesis]. University of Missouri – Columbia; 2009. [cited 2020 Jan 29]. Available from: http://hdl.handle.net/10355/9679.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kirkpatrick, James R. 1. Examination of exogenous estrogenic chemical exposure and altered fetal nutrition in the CD-1 mouse fetus. [Thesis]. University of Missouri – Columbia; 2009. Available from: http://hdl.handle.net/10355/9679

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Western Australia

9. Breckler, Liza Anne. The role of maternal-fetal interactions on the aetiology of allergic disease.

Degree: PhD, 2008, University of Western Australia

URL: http://repository.uwa.edu.au:80/R/?func=dbin-jump-full&object_id=12767&local_base=GEN01-INS01

► [Truncated abstract] The dramatic increase in the expression of allergic diseases such as asthma and allergy over the last 20-30 years has highlighted the urgent… (more)

▼ [Truncated abstract] The dramatic increase in the expression of allergic diseases such as asthma and allergy over the last 20-30 years has highlighted the urgent need to identify causative factors. It was hypothesised that direct immune interactions between mother and fetus contribute to the cytokine milieu of pregnancy, thus influencing immune maturation after birth. Further it was speculated that the cytokine responses produced as a result of maternalfetal interactions are Th-2 skewed in women allergic disease, which programmes their offspring towards developing an allergic phenotype after birth. To test this hypothesis a cohort of 169 pregnant women were recruited at 20 weeks gestation and defined as allergic or non-allergic based on both clinical history and skin prick test sensitisation. These women and their infants were followed up throughout pregnancy (20 weeks, 30 weeks, 36 weeks gestation and 6 weeks post-partum) and up to 2.5 years of age. Mixed lymphocyte reactions (MLR) were used to measure maternal cytokine (IL-6, IL-10, IL-13 and IFN-) and lymphoproliferative responses to fetal alloantigens at each pregnancy time-point. Human leukocyte antigen (HLA) typing of mothers and infants were performed to assess the effect of HLA mismatch on maternal MLR responses to their fetus. After delivery, mononuclear cells (MNC) were isolated from cord blood (CB) and stimulated with allergens, mitogen and toll-like receptor (TLR) ligands. .... As IL-6 also participates in adaptive immunity by promoting Th-2 differentiation it is proposed that the production of IL-6 as a results of maternal encounters with paternal antigens during pregnancy, contribute to the Th-2 skewed responses observed universally in most infants at birth. Associations between maternal-fetal interaction and clinical outcomes in infancy: Although clinical signs of allergy in infancy were not the main outcome measure of this thesis, there were interesting, yet complex relationships between the production of these maternal cytokines towards the fetus and allergic disease at infant follow-ups. Increased maternal IFN-γ to fetal alloantigen was associated with asthma at 2.5 years and a trend towards recurrent wheeze at 12 months. In contrast decreased maternal IL-13 production was associated with IgE mediated food allergy at 12 months. Adjusting for maternal allergy and other potential confounders including infant gender, method of delivery, HLA mismatch, and paternal allergy did not account for these relationships. Further follow-ups of these infants are required to determine if these relationship last in to early childhood. In conclusion, the findings of this thesis provides further support for the hypothesis that immune responses at birth are programmed prenatally, and that this programming has implications later in life. Importantly, the placenta is the immunologically active interface between mother and fetus during pregnancy. Therefore it is emphasised that there is a crucial need for future research to focus on early immune programming at the…

Subjects/Keywords: Allergy; Maternal-fetal exchange; Cytokines; Fetus; Fetus; Pregnancy; Allergic Disease; Immunity

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Breckler, L. A. (2008). The role of maternal-fetal interactions on the aetiology of allergic disease. (Doctoral Dissertation). University of Western Australia. Retrieved from http://repository.uwa.edu.au:80/R/?func=dbin-jump-full&object_id=12767&local_base=GEN01-INS01

Chicago Manual of Style (16^th Edition):

Breckler, Liza Anne. “The role of maternal-fetal interactions on the aetiology of allergic disease.” 2008. Doctoral Dissertation, University of Western Australia. Accessed January 29, 2020. http://repository.uwa.edu.au:80/R/?func=dbin-jump-full&object_id=12767&local_base=GEN01-INS01.

MLA Handbook (7^th Edition):

Breckler, Liza Anne. “The role of maternal-fetal interactions on the aetiology of allergic disease.” 2008. Web. 29 Jan 2020.

Vancouver:

Breckler LA. The role of maternal-fetal interactions on the aetiology of allergic disease. [Internet] [Doctoral dissertation]. University of Western Australia; 2008. [cited 2020 Jan 29]. Available from: http://repository.uwa.edu.au:80/R/?func=dbin-jump-full&object_id=12767&local_base=GEN01-INS01.

Council of Science Editors:

Breckler LA. The role of maternal-fetal interactions on the aetiology of allergic disease. [Doctoral Dissertation]. University of Western Australia; 2008. Available from: http://repository.uwa.edu.au:80/R/?func=dbin-jump-full&object_id=12767&local_base=GEN01-INS01

University of Hong Kong

10. Woo, Chit-shing, Jackson. Ochratoxin A: endocrine disruption potential,transplacental kinetics and maternal exposure assessment.

Degree: PhD, 2012, University of Hong Kong

URL: Woo, C. J. [胡哲誠]. (2012). Ochratoxin A : endocrine disruption potential, transplacental kinetics and maternal exposure assessment. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b4979954 ; http://dx.doi.org/10.5353/th_b4979954 ; http://hdl.handle.net/10722/181520

► Mycotoxin contamination in food commodities is an age-old problem. Due to the detrimental impact of mycotoxins on human health, exposure to mycotoxins and their health… (more)

▼ Mycotoxin contamination in food commodities is an age-old problem. Due to the detrimental impact of mycotoxins on human health, exposure to mycotoxins and their health implications have been increasingly recognized. Ochratoxin A (OTA), one of the mycotoxins, has been found to cause diverse toxicities in animals, with potential impact on human health. OTA has been reported to be teratogenic and interfere with steroidogenesis in vivo. Chronic exposure of pregnant women to OTA may be hazardous for the human foetus, especially when endocrine and developmental toxicities are taken into consideration. Accordingly, in the first part of this project, I hypothesized that OTA may interfere with enzymes involved in human placental steroidogenesis. By evaluation of human placental 3β–hydroxysteroid dehydrogenase/isomerase (3β-HSD) at both mRNA and protein (hormonal) levels, my results showed that OTA could up-regulate 3β-HSD1 expression in human placental cells with concentration relevant to human exposure. This study is the first to report the endocrine disruption potential of OTA in human placental cells. As several mycotoxins have been demonstrated previously to cross human placental barrier and OTA has been associated with developmental toxicity in vivo, I further hypothesized that OTA may be transferred through human placenta and accumulate in foetal compartment. In the second part of this project, human perfused placenta was used to investigate the placental toxicokinetics of OTA using concentrations found in serum of pregnant women. Findings from this study clearly showed that the transfer of OTA through term human placenta was minimal, contradicting the existing epidemiological studies reporting higher foetal OTA levels than maternal. This is the first study where transplacental kinetics of OTA has been studied in human perfused placenta. To assess the relevance of the study findings, it is very important to provide information on maternal OTA exposure during pregnancy. Currently there is limited information regarding OTA exposure of pregnant women. The third part of this project aimed at evaluating the frequency and level of exposure to OTA in pregnant women from Egypt, where exposure to dietary mycotoxins is common due to the environmental conditions. Biomonitoring of both serum and urinary OTA levels showed that more than 70% of pregnant women were exposed to OTA with a geometric mean of 0.27 ng/ml in serum and 37.21 pg/mg creatinine in urine indicating frequent exposure of this subpopulation. As an ultimate aim, maternal-foetal risk assessment served as a conclusive part of this project to predict and evaluate both maternal and foetal risk of exposure to OTA during pregnancy. Data from the exposure of pregnant women in Egypt to OTA were further ultilized to conduct maternal-foetal risk assessment in relation to OTA exposure. Based on the refined Klaassen equation for exposure estimation during pregnancy and the benchmark dose approach for risk assessment, this subpopulation of pregnant women generally…

Subjects/Keywords: Placenta - physiology.; Fetus - Physiology.; Endocrine toxicology.; Mycotoxins.

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APA (6^th Edition):

Woo, Chit-shing, J. (2012). Ochratoxin A: endocrine disruption potential,transplacental kinetics and maternal exposure assessment. (Doctoral Dissertation). University of Hong Kong. Retrieved from Woo, C. J. [胡哲誠]. (2012). Ochratoxin A : endocrine disruption potential, transplacental kinetics and maternal exposure assessment. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b4979954 ; http://dx.doi.org/10.5353/th_b4979954 ; http://hdl.handle.net/10722/181520

Chicago Manual of Style (16^th Edition):

Woo, Chit-shing, Jackson. “Ochratoxin A: endocrine disruption potential,transplacental kinetics and maternal exposure assessment.” 2012. Doctoral Dissertation, University of Hong Kong. Accessed January 29, 2020. Woo, C. J. [胡哲誠]. (2012). Ochratoxin A : endocrine disruption potential, transplacental kinetics and maternal exposure assessment. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b4979954 ; http://dx.doi.org/10.5353/th_b4979954 ; http://hdl.handle.net/10722/181520.

MLA Handbook (7^th Edition):

Woo, Chit-shing, Jackson. “Ochratoxin A: endocrine disruption potential,transplacental kinetics and maternal exposure assessment.” 2012. Web. 29 Jan 2020.

Vancouver:

Woo, Chit-shing J. Ochratoxin A: endocrine disruption potential,transplacental kinetics and maternal exposure assessment. [Internet] [Doctoral dissertation]. University of Hong Kong; 2012. [cited 2020 Jan 29]. Available from: Woo, C. J. [胡哲誠]. (2012). Ochratoxin A : endocrine disruption potential, transplacental kinetics and maternal exposure assessment. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b4979954 ; http://dx.doi.org/10.5353/th_b4979954 ; http://hdl.handle.net/10722/181520.

Council of Science Editors:

Woo, Chit-shing J. Ochratoxin A: endocrine disruption potential,transplacental kinetics and maternal exposure assessment. [Doctoral Dissertation]. University of Hong Kong; 2012. Available from: Woo, C. J. [胡哲誠]. (2012). Ochratoxin A : endocrine disruption potential, transplacental kinetics and maternal exposure assessment. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b4979954 ; http://dx.doi.org/10.5353/th_b4979954 ; http://hdl.handle.net/10722/181520

University of Oxford

11. Fore, Ian Michael. The distribution of cardiac output in the fetus.

Degree: 1982, University of Oxford

URL: http://ora.ox.ac.uk/objects/uuid:f9a0ac22-2baf-408f-83e5-9eedb5809014 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.345430

Subjects/Keywords: 612; Fetus : Hypertension

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APA (6^th Edition):

Fore, I. M. (1982). The distribution of cardiac output in the fetus. (Doctoral Dissertation). University of Oxford. Retrieved from http://ora.ox.ac.uk/objects/uuid:f9a0ac22-2baf-408f-83e5-9eedb5809014 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.345430

Chicago Manual of Style (16^th Edition):

Fore, Ian Michael. “The distribution of cardiac output in the fetus.” 1982. Doctoral Dissertation, University of Oxford. Accessed January 29, 2020. http://ora.ox.ac.uk/objects/uuid:f9a0ac22-2baf-408f-83e5-9eedb5809014 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.345430.

MLA Handbook (7^th Edition):

Fore, Ian Michael. “The distribution of cardiac output in the fetus.” 1982. Web. 29 Jan 2020.

Vancouver:

Fore IM. The distribution of cardiac output in the fetus. [Internet] [Doctoral dissertation]. University of Oxford; 1982. [cited 2020 Jan 29]. Available from: http://ora.ox.ac.uk/objects/uuid:f9a0ac22-2baf-408f-83e5-9eedb5809014 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.345430.

Council of Science Editors:

Fore IM. The distribution of cardiac output in the fetus. [Doctoral Dissertation]. University of Oxford; 1982. Available from: http://ora.ox.ac.uk/objects/uuid:f9a0ac22-2baf-408f-83e5-9eedb5809014 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.345430

University of Western Australia

12. Samnakay, Naeem. Antenatal bladder outflow obstruction : effects of morphology and apoptosis in the fetal kidney, and effects on fetal ACTH and cortisol levels in an ovine model.

Degree: M.Med.Sc., 2008, University of Western Australia

URL: http://repository.uwa.edu.au:80/R/?func=dbin-jump-full&object_id=10157&local_base=GEN01-INS01

► Posterior urethral valves cause bladder outflow obstruction and damage to the developing fetal kidney. Posterior urethral valves affect 1 in 8000 new-born males. A third… (more)

▼ Posterior urethral valves cause bladder outflow obstruction and damage to the developing fetal kidney. Posterior urethral valves affect 1 in 8000 new-born males. A third of these children develop end stage renal failure by adolescence, despite valve ablation in the early post-natal period, implying that majority of the damage to the kidneys occurs in utero. How does this damage occur, and should we intervene in utero? The answers to these questions require further research, and are the basis to this thesis. This thesis focused on the effect bladder outflow obstruction has on morphology and apoptosis in the fetal kidney in a fetal lamb model. It also looked at the effect of bladder outflow obstruction on fetal stress hormone levels. Bladder outflow obstruction was created surgically in fetal lambs at day 70 of gestation, and fetal kidneys were analysed at day 2, 5, 10, 20 and 30 after creation of obstruction. Controls undergoing sham surgery were used for comparison. Four aspects were investigated: - effects of bladder outflow obstruction on renal histology effects of bladder outflow obstruction on expression of pro-apoptosis gene Bax and anti-apoptosis gene Bcl-X - effects of bladder outflow obstruction on renal regional apoptosis effects of bladder outflow obstruction on serum fetal ACTH and cortisol levels. Bladder outflow obstruction resulted in sequential morphological change in the fetal kidney over time. By 2 days post-obstruction, cystic change was noted. In addition, patchy attenuation of the nephrogenic blastema was evident by 5 days post-obstruction, with more confluent blastemal attenuation as well as generalized renal architectural disorganization by 10 days post-obstruction. By 20 and 30 days post-obstruction, cystic renal dysplasia had developed. Bladder outflow obstruction resulted in an increase in the ratio of renal expression of pro-apoptosis gene Bax to anti-apoptosis gene Bcl-X. Regional apoptosis counts showed increased tubular apoptosis compared to controls at 2 days post-obstruction, and increased blastemal apoptosis compared to controls at 5 days post-obstruction. By 10 days post-obstruction, blastemal apoptosis counts were reduced compared to controls. There were no significant differences in fetal serum ACTH and cortisol levels between fetal lambs with bladder outflow obstruction and controls. In conclusion, the results of this thesis outline the spectrum of morphological change in the fetal kidney over 30 days of bladder outflow obstruction. They show that detectable changes in morphology occur within two days of bladder outflow obstruction. Likewise, detectable changes in gene expression occur within 2 days of bladder outflow obstruction. The increased ratio of expression of Bax to Bcl-X suggests a swing towards increased apoptosis in response to bladder outflow obstruction. Further research is required to ascertain if these changes are reversible. However, the early onset of these changes as shown in this thesis suggests that any fetal intervention to protect the fetal kidney from the…

Subjects/Keywords: Hydronephrosis; Fetus; Fetal hydronephrosis; Posterior urethral valves

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APA (6^th Edition):

Samnakay, N. (2008). Antenatal bladder outflow obstruction : effects of morphology and apoptosis in the fetal kidney, and effects on fetal ACTH and cortisol levels in an ovine model. (Masters Thesis). University of Western Australia. Retrieved from http://repository.uwa.edu.au:80/R/?func=dbin-jump-full&object_id=10157&local_base=GEN01-INS01

Chicago Manual of Style (16^th Edition):

Samnakay, Naeem. “Antenatal bladder outflow obstruction : effects of morphology and apoptosis in the fetal kidney, and effects on fetal ACTH and cortisol levels in an ovine model.” 2008. Masters Thesis, University of Western Australia. Accessed January 29, 2020. http://repository.uwa.edu.au:80/R/?func=dbin-jump-full&object_id=10157&local_base=GEN01-INS01.

MLA Handbook (7^th Edition):

Samnakay, Naeem. “Antenatal bladder outflow obstruction : effects of morphology and apoptosis in the fetal kidney, and effects on fetal ACTH and cortisol levels in an ovine model.” 2008. Web. 29 Jan 2020.

Vancouver:

Samnakay N. Antenatal bladder outflow obstruction : effects of morphology and apoptosis in the fetal kidney, and effects on fetal ACTH and cortisol levels in an ovine model. [Internet] [Masters thesis]. University of Western Australia; 2008. [cited 2020 Jan 29]. Available from: http://repository.uwa.edu.au:80/R/?func=dbin-jump-full&object_id=10157&local_base=GEN01-INS01.

Council of Science Editors:

Samnakay N. Antenatal bladder outflow obstruction : effects of morphology and apoptosis in the fetal kidney, and effects on fetal ACTH and cortisol levels in an ovine model. [Masters Thesis]. University of Western Australia; 2008. Available from: http://repository.uwa.edu.au:80/R/?func=dbin-jump-full&object_id=10157&local_base=GEN01-INS01

University of Sydney

13. Eviston, David. Fetal Thymus Changes in Pre-eclampsia and the Developmental Origins of Allergic Disease .

Degree: 2018, University of Sydney

URL: http://hdl.handle.net/2123/18414

► Pre-eclampsia is a systemic disorder unique to human pregnancy and a leading cause of maternal-fetal morbidity and mortality worldwide. While its exact aetiology remains unknown,… (more)

▼ Pre-eclampsia is a systemic disorder unique to human pregnancy and a leading cause of maternal-fetal morbidity and mortality worldwide. While its exact aetiology remains unknown, maternal immune changes in pre-eclampsia, including reduced regulatory T cells (Treg), support a breakdown in maternal-fetal immune tolerance. The current immune theory for pre-eclampsia is likely to be incomplete, however, as fetal immune function is not considered. Although obvious restrictions limit access to the human fetus, the thymus, a primary immune organ, can be readily observed by ultrasound at mid-gestation. Fetal thymus changes observed via ultrasound can therefore offer non-invasive insight into fetal immunity. Beyond its immediate consequences to maternal-fetal wellbeing, pre-eclampsia has been linked to childhood allergy. This suggests fetal programming of allergic disease, a concept also supported by studies linking newborn head size with allergy. A possible explanation for this link centres on altered neurotrophin levels, including BDNF. Neurotrophins are important mediators of brain growth and development, which are also dysregulated in allergic disease. Cord blood BDNF levels are also altered in pre-eclampsia. We therefore hypothesized that pre-eclampsia would be associated with altered fetal head growth. This thesis consists of five publications. Firstly, Chapters 3 and 4, observed a smaller fetal thymus in pre- eclampsia, with a smaller fetal thymus preceding clinical disease. The third study, Chapter 5, included a large prospective study which confirmed the findings of Chapter 4. Chapter 5 also included thymus histopathology, which revealed dramatic apoptosis of thymocytes in pre-eclampsia, especially affecting Treg cells. Adding to our theory of neurotrophin dysregulation as a possible factor in fetal programming, Chapter 6 demonstrated increased fetal head growth in pre-eclampsia. Finally, Chapter 7 found reduced fetal head size at mid-gestation to be associated with childhood allergy. In summary, this research has shown fetal thymus changes to precede clinical disease in pre-eclampsia, possibly reflecting an active role for fetal immunity in disease pathogenesis. Our findings also support the developmental programming of allergic disease.

Subjects/Keywords: fetus; thymus; ultrasound; pre-eclampsia; allergy; developmental

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APA (6^th Edition):

Eviston, D. (2018). Fetal Thymus Changes in Pre-eclampsia and the Developmental Origins of Allergic Disease . (Thesis). University of Sydney. Retrieved from http://hdl.handle.net/2123/18414

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Eviston, David. “Fetal Thymus Changes in Pre-eclampsia and the Developmental Origins of Allergic Disease .” 2018. Thesis, University of Sydney. Accessed January 29, 2020. http://hdl.handle.net/2123/18414.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Eviston, David. “Fetal Thymus Changes in Pre-eclampsia and the Developmental Origins of Allergic Disease .” 2018. Web. 29 Jan 2020.

Vancouver:

Eviston D. Fetal Thymus Changes in Pre-eclampsia and the Developmental Origins of Allergic Disease . [Internet] [Thesis]. University of Sydney; 2018. [cited 2020 Jan 29]. Available from: http://hdl.handle.net/2123/18414.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Eviston D. Fetal Thymus Changes in Pre-eclampsia and the Developmental Origins of Allergic Disease . [Thesis]. University of Sydney; 2018. Available from: http://hdl.handle.net/2123/18414

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

14. Sibley, Colin. The Nutrient Exchange Phenotype of the Placenta in FetalGrowth Restriction: Characterization, Adaptation and Regulation.

Degree: 2013, University of Manchester

URL: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:205138

► An essential function of the placenta is the exchange of nutrients, and wasteproducts of fetal metabolism, between mother and fetus. The placenta thereforeplays a key… (more)

▼ An essential function of the placenta is the exchange of nutrients, and wasteproducts of fetal metabolism, between mother and fetus. The placenta thereforeplays a key role in determining fetal growth and size at birth. Fetal growthrestriction (FGR) is a complication affecting around 5% of pregnancies. Thereare several possible causes of FGR but the most common in the Western world isplacental dysfunction. The FGR baby is at much greater risk of stillbirth andneurodevelopmental morbidities than the normally grown baby. Furthermore, thesmaller baby per se has an increased risk of a range of morbidities as an adult.The thrust of the work covered in this thesis was to improve understanding of theabnormalities in placental exchange physiology associated with FGR. The goalwas (and is) to develop new placental diagnostic biomarkers for the disease andnew treatments based on improving placental function.The first tranche of work described showed that there are specific changes intransporter activities in the placenta in FGR. My colleagues and I showed thatSystem A amino acid transporter activity in the microvillous plasma membrane(MVM) of the syncytiotrophoblast (transporting epithelium of the placenta) isreduced, per mg membrane protein, and that this reduction is related to theseverity of the disease. This contrasted with our observation in normal pregnancythat MVM System A activity, per mg protein, is inversely related to size of the babyat birth, and first suggested the concept of placental adaptation to fetal growthdemand. We, and others, went on to show that a number of other transporters inthe syncytiotrophoblast are altered in FGR. However, not all transporters areaffected and at least one is upregulated. This led me to hypothesise that some ofthese changes are causal to FGR and some are responses, or adaptations, toabnormal fetal growth. The direct causes of transporter activity changes are notknown but our work, and that of others, suggests that glucocorticoids play a role.We also showed that transporter activities in the placenta are affected in othercomplications where fetal growth is aberrant. Furthermore, we provided evidencethat denuded areas of the syncytiotrophoblast might be the morphologicalcorrelate of a route of passive transfer of hydrophilic solutes across the placenta.Our studies in a mouse model of FGR suggest that abnormalities in such aparacellular route may be part of the placental dysfunction in the disease.In the final group of publications of this thesis I describe work showing gestationalchanges in placental transporter activities. I suggest that these are primarilyregulated to maintain fetal growth trajectory, but may also provide for specificnutrient demands at particular times in gestation. This explanation was supportedby work with genetically modified mice showing experimentally that placentaltransporter activity is regulated, or adapted, in relation to fetal growth demand. Itappears from several studies described here that there is a matching of fetalgrowth demand and placental nutrient… Advisors/Committee Members: Aplin, John.

Subjects/Keywords: Placenta; Fetus

…own right. Abnormal fetal growth may be defined as the failure of a fetus to reach its… …during early pregnancy, improving blood flow to the fast growing placenta and fetus (… …the interactions between fetus and placenta and, most recently, exploration of methods by… …the greater will be its ability to transport nutrient to the fetus. However, this seemed… …the time) to keep the total number of transporters per placenta and per fetus constant…

13 more images…

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APA (6^th Edition):

Sibley, C. (2013). The Nutrient Exchange Phenotype of the Placenta in FetalGrowth Restriction: Characterization, Adaptation and Regulation. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:205138

Chicago Manual of Style (16^th Edition):

Sibley, Colin. “The Nutrient Exchange Phenotype of the Placenta in FetalGrowth Restriction: Characterization, Adaptation and Regulation.” 2013. Doctoral Dissertation, University of Manchester. Accessed January 29, 2020. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:205138.

MLA Handbook (7^th Edition):

Sibley, Colin. “The Nutrient Exchange Phenotype of the Placenta in FetalGrowth Restriction: Characterization, Adaptation and Regulation.” 2013. Web. 29 Jan 2020.

Vancouver:

Sibley C. The Nutrient Exchange Phenotype of the Placenta in FetalGrowth Restriction: Characterization, Adaptation and Regulation. [Internet] [Doctoral dissertation]. University of Manchester; 2013. [cited 2020 Jan 29]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:205138.

Council of Science Editors:

Sibley C. The Nutrient Exchange Phenotype of the Placenta in FetalGrowth Restriction: Characterization, Adaptation and Regulation. [Doctoral Dissertation]. University of Manchester; 2013. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:205138

University of Dundee

15. Marx, Viola. Fetal responsiveness to auditory and tactile stimulation.

Degree: PhD, 2018, University of Dundee

URL: http://hdl.handle.net/10588/c3a21d95-627d-4f82-be92-d6dc9c3837b9

► The aim of this thesis was to examine fetal behavioural responses to auditory and tactile stimulation. Responses were examined for the second- and third-trimester fetuses… (more)

▼ The aim of this thesis was to examine fetal behavioural responses to auditory and tactile stimulation. Responses were examined for the second- and third-trimester fetuses (second-trimester ≤ 27 gestational weeks (wGA), third- trimester >27 wGA), in both experiments, respectively. Experiment 1 of this thesis examined fetal behavioural responses to the mother’s recorded and live voice, contrasting findings to an environmental sound and silent control conditions. Behavioural responses of 30 fetuses trimester (20-33 wGA, N = 13 in the 2nd and N = 17 in the 3rd trimester) Were examined in the following conditions were explored: (1) mother’s live, (2) and recorded voice, (3) an environmental sound, and (4) a silent control condition. Findings showed the strongest responses to maternal sounds as well as differential responses between gestational age groups. Younger fetuses displayed an arousal response to maternal voice, whereas third-trimester fetuses displayed an orientating response. The aim of Experiment 2 was to examine whether fetuses can differentiate between different human sources of tactile stimulation of the maternal abdomen. Behavioural responses of 28 fetuses (20-33 wGA, N = 15 in the 2nd and N = 13 in the 3rd trimester) were examined across four conditions: (1) mother’s, (2) father’s, and (3) stranger’s touch, as well as a (4) silent control condition. Differential responses to the tactile stimulation were found, especially in reaching of the uterine wall, and self- touch across the four conditions. Third- trimester fetuses touched the uterus wall for significantly longer than fetuses in the second-trimester. The strongest responses were found to the mother’s touch. Further differential responses were found between age groups, with third-trimester fetuses clearly differentiating between different sources of tactile stimulation, while second-trimester fetuses hardly showed differentiated responses. It is suggested that maturational differences in both experiments are due to the fetal development of the central nervous system, and might indicate the emergence of a proprioceptive self-awareness by the 3rd trimester.

Subjects/Keywords: Fetus; Fetal Psychology; Mother; Touch; Tactile; Ultrasound

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APA (6^th Edition):

Marx, V. (2018). Fetal responsiveness to auditory and tactile stimulation. (Doctoral Dissertation). University of Dundee. Retrieved from http://hdl.handle.net/10588/c3a21d95-627d-4f82-be92-d6dc9c3837b9

Chicago Manual of Style (16^th Edition):

Marx, Viola. “Fetal responsiveness to auditory and tactile stimulation.” 2018. Doctoral Dissertation, University of Dundee. Accessed January 29, 2020. http://hdl.handle.net/10588/c3a21d95-627d-4f82-be92-d6dc9c3837b9.

MLA Handbook (7^th Edition):

Marx, Viola. “Fetal responsiveness to auditory and tactile stimulation.” 2018. Web. 29 Jan 2020.

Vancouver:

Marx V. Fetal responsiveness to auditory and tactile stimulation. [Internet] [Doctoral dissertation]. University of Dundee; 2018. [cited 2020 Jan 29]. Available from: http://hdl.handle.net/10588/c3a21d95-627d-4f82-be92-d6dc9c3837b9.

Council of Science Editors:

Marx V. Fetal responsiveness to auditory and tactile stimulation. [Doctoral Dissertation]. University of Dundee; 2018. Available from: http://hdl.handle.net/10588/c3a21d95-627d-4f82-be92-d6dc9c3837b9

16. Yunusova, Roza. Effects of Maternal Nutrition, Intrauterine Growth Restriction (IUGR), and Estrogen (E2) Supplementation on Placental and Fetal Intestinal Growth and Development in Sheep.

Degree: MS, Animal Sciences, 2012, North Dakota State University

URL: http://hdl.handle.net/10365/26539

► The placenta and fetal intestines are two key nutrient transport organs that sustain and nurture growing fetus. Insufficient placental development and consequently inadequate fetal nutrient… (more)

Subjects/Keywords: Mothers – Nutrition.; Fetus – Nutrition.; Intestines.; Sheep.; Placenta.

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APA (6^th Edition):

Yunusova, R. (2012). Effects of Maternal Nutrition, Intrauterine Growth Restriction (IUGR), and Estrogen (E2) Supplementation on Placental and Fetal Intestinal Growth and Development in Sheep. (Masters Thesis). North Dakota State University. Retrieved from http://hdl.handle.net/10365/26539

Chicago Manual of Style (16^th Edition):

Yunusova, Roza. “Effects of Maternal Nutrition, Intrauterine Growth Restriction (IUGR), and Estrogen (E2) Supplementation on Placental and Fetal Intestinal Growth and Development in Sheep.” 2012. Masters Thesis, North Dakota State University. Accessed January 29, 2020. http://hdl.handle.net/10365/26539.

MLA Handbook (7^th Edition):

Yunusova, Roza. “Effects of Maternal Nutrition, Intrauterine Growth Restriction (IUGR), and Estrogen (E2) Supplementation on Placental and Fetal Intestinal Growth and Development in Sheep.” 2012. Web. 29 Jan 2020.

Vancouver:

Yunusova R. Effects of Maternal Nutrition, Intrauterine Growth Restriction (IUGR), and Estrogen (E2) Supplementation on Placental and Fetal Intestinal Growth and Development in Sheep. [Internet] [Masters thesis]. North Dakota State University; 2012. [cited 2020 Jan 29]. Available from: http://hdl.handle.net/10365/26539.

Council of Science Editors:

Yunusova R. Effects of Maternal Nutrition, Intrauterine Growth Restriction (IUGR), and Estrogen (E2) Supplementation on Placental and Fetal Intestinal Growth and Development in Sheep. [Masters Thesis]. North Dakota State University; 2012. Available from: http://hdl.handle.net/10365/26539

Queens University

17. Lee, Grace. Fetal and Newborn Auditory Processing of the Mother's and Father's Voice .

Degree: Nursing, 2010, Queens University

URL: http://hdl.handle.net/1974/6027

► Term fetuses show differential heart rate responses to their mother’s vs. a female stranger’s voice and newborns show a preference for their mother’s vs. a… (more)

Subjects/Keywords: Fetus; Newborn; Audition; Language; Voice; Learning

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APA (6^th Edition):

Lee, G. (2010). Fetal and Newborn Auditory Processing of the Mother's and Father's Voice . (Thesis). Queens University. Retrieved from http://hdl.handle.net/1974/6027

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Lee, Grace. “Fetal and Newborn Auditory Processing of the Mother's and Father's Voice .” 2010. Thesis, Queens University. Accessed January 29, 2020. http://hdl.handle.net/1974/6027.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Lee, Grace. “Fetal and Newborn Auditory Processing of the Mother's and Father's Voice .” 2010. Web. 29 Jan 2020.

Vancouver:

Lee G. Fetal and Newborn Auditory Processing of the Mother's and Father's Voice . [Internet] [Thesis]. Queens University; 2010. [cited 2020 Jan 29]. Available from: http://hdl.handle.net/1974/6027.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Lee G. Fetal and Newborn Auditory Processing of the Mother's and Father's Voice . [Thesis]. Queens University; 2010. Available from: http://hdl.handle.net/1974/6027

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Rutgers University

18. Saeki, EIko, 1979-. Contested boundaries of personhood: the moral status of the fetus and infant in late Tokugawa Japan.

Degree: PhD, Sociology, 2017, Rutgers University

URL: https://rucore.libraries.rutgers.edu/rutgers-lib/55675/

►

This dissertation examines the competing notions of personhood in the late Tokugawa era in Japan (from the mid-eighteenth to the late nineteenth centuries), by investigating… (more)

Subjects/Keywords: Fetus – Moral and ethical aspects – Japan

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APA (6^th Edition):

Saeki, EIko, 1. (2017). Contested boundaries of personhood: the moral status of the fetus and infant in late Tokugawa Japan. (Doctoral Dissertation). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/55675/

Chicago Manual of Style (16^th Edition):

Saeki, EIko, 1979-. “Contested boundaries of personhood: the moral status of the fetus and infant in late Tokugawa Japan.” 2017. Doctoral Dissertation, Rutgers University. Accessed January 29, 2020. https://rucore.libraries.rutgers.edu/rutgers-lib/55675/.

MLA Handbook (7^th Edition):

Saeki, EIko, 1979-. “Contested boundaries of personhood: the moral status of the fetus and infant in late Tokugawa Japan.” 2017. Web. 29 Jan 2020.

Vancouver:

Saeki, EIko 1. Contested boundaries of personhood: the moral status of the fetus and infant in late Tokugawa Japan. [Internet] [Doctoral dissertation]. Rutgers University; 2017. [cited 2020 Jan 29]. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/55675/.

Council of Science Editors:

Saeki, EIko 1. Contested boundaries of personhood: the moral status of the fetus and infant in late Tokugawa Japan. [Doctoral Dissertation]. Rutgers University; 2017. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/55675/

Uppsala University

19. Lindgren, Karin. Kvinnors upplevelser av smärta och blödning samt möjlighet att upptäcka fostret i samband med hemabort : En enkätstudie vid två kliniker i Sverige.

Degree: Women's and Children's Health, 2012, Uppsala University

URL: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-175737

► The purpose of this study was to investigate women's experiences of pain, bleeding,to discover the fetus, hospitalization associated with medical abortion at home and… (more)

Subjects/Keywords: Medical abortion; Home; Misoprostol; Bleeding; Pain; Fetus.

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APA (6^th Edition):

Lindgren, K. (2012). Kvinnors upplevelser av smärta och blödning samt möjlighet att upptäcka fostret i samband med hemabort : En enkätstudie vid två kliniker i Sverige. (Thesis). Uppsala University. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-175737

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Lindgren, Karin. “Kvinnors upplevelser av smärta och blödning samt möjlighet att upptäcka fostret i samband med hemabort : En enkätstudie vid två kliniker i Sverige.” 2012. Thesis, Uppsala University. Accessed January 29, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-175737.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Lindgren, Karin. “Kvinnors upplevelser av smärta och blödning samt möjlighet att upptäcka fostret i samband med hemabort : En enkätstudie vid två kliniker i Sverige.” 2012. Web. 29 Jan 2020.

Vancouver:

Lindgren K. Kvinnors upplevelser av smärta och blödning samt möjlighet att upptäcka fostret i samband med hemabort : En enkätstudie vid två kliniker i Sverige. [Internet] [Thesis]. Uppsala University; 2012. [cited 2020 Jan 29]. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-175737.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Lindgren K. Kvinnors upplevelser av smärta och blödning samt möjlighet att upptäcka fostret i samband med hemabort : En enkätstudie vid två kliniker i Sverige. [Thesis]. Uppsala University; 2012. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-175737

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Gothenburg / Göteborgs Universitet

20. Karlsson, Kirsten, 1931-. Intrauterine asphyxia : an experimental study in rabbits and sheep with special reference to uterine blood flow and fetal cerebral reactions.

Degree: 1974, University of Gothenburg / Göteborgs Universitet

URL: http://hdl.handle.net/2077/12192

Subjects/Keywords: Asphyxia; Fetus: physiology

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APA (6^th Edition):

Karlsson, Kirsten, 1. (1974). Intrauterine asphyxia : an experimental study in rabbits and sheep with special reference to uterine blood flow and fetal cerebral reactions. (Thesis). University of Gothenburg / Göteborgs Universitet. Retrieved from http://hdl.handle.net/2077/12192

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Karlsson, Kirsten, 1931-. “Intrauterine asphyxia : an experimental study in rabbits and sheep with special reference to uterine blood flow and fetal cerebral reactions.” 1974. Thesis, University of Gothenburg / Göteborgs Universitet. Accessed January 29, 2020. http://hdl.handle.net/2077/12192.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Karlsson, Kirsten, 1931-. “Intrauterine asphyxia : an experimental study in rabbits and sheep with special reference to uterine blood flow and fetal cerebral reactions.” 1974. Web. 29 Jan 2020.

Vancouver:

Karlsson, Kirsten 1. Intrauterine asphyxia : an experimental study in rabbits and sheep with special reference to uterine blood flow and fetal cerebral reactions. [Internet] [Thesis]. University of Gothenburg / Göteborgs Universitet; 1974. [cited 2020 Jan 29]. Available from: http://hdl.handle.net/2077/12192.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Karlsson, Kirsten 1. Intrauterine asphyxia : an experimental study in rabbits and sheep with special reference to uterine blood flow and fetal cerebral reactions. [Thesis]. University of Gothenburg / Göteborgs Universitet; 1974. Available from: http://hdl.handle.net/2077/12192

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Michigan State University

21. Fowler, Edward Herbert. The developmental histology of the integument of fetal pigs.

Degree: MS, 1962, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:9667

Subjects/Keywords: Skin; Swine; Fetus

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APA (6^th Edition):

Fowler, E. H. (1962). The developmental histology of the integument of fetal pigs. (Masters Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:9667

Chicago Manual of Style (16^th Edition):

Fowler, Edward Herbert. “The developmental histology of the integument of fetal pigs.” 1962. Masters Thesis, Michigan State University. Accessed January 29, 2020. http://etd.lib.msu.edu/islandora/object/etd:9667.

MLA Handbook (7^th Edition):

Fowler, Edward Herbert. “The developmental histology of the integument of fetal pigs.” 1962. Web. 29 Jan 2020.

Vancouver:

Fowler EH. The developmental histology of the integument of fetal pigs. [Internet] [Masters thesis]. Michigan State University; 1962. [cited 2020 Jan 29]. Available from: http://etd.lib.msu.edu/islandora/object/etd:9667.

Council of Science Editors:

Fowler EH. The developmental histology of the integument of fetal pigs. [Masters Thesis]. Michigan State University; 1962. Available from: http://etd.lib.msu.edu/islandora/object/etd:9667

Universitat de Barcelona

22. Illa Armengol, Míriam. Brain effects of fetal growth restriction and their prevention in an animal model.

Degree: 2017, Universitat de Barcelona

URL: http://hdl.handle.net/10803/565667

► BACKGROUND: Chronic hypoxia due to placental insufficiency and prenatal undernutrition are probably the two major causes worldwide of an adverse intrauterine environment having an impact… (more)

▼ BACKGROUND: Chronic hypoxia due to placental insufficiency and prenatal undernutrition are probably the two major causes worldwide of an adverse intrauterine environment having an impact on neurodevelopment. Clinically, both situations manifest as an intrauterine growth restriction (IUGR), a situation defined as a significant reduction in fetal growth resulting in a birth weight below the 10th percentile. This situation is a well-recognized cause of neurobehavioral and cognitive impairments extending beyond childhood and early adulthood period. Although all these evidence, the structural ground of these functional impairments and the pathophysiological mechanisms are not fully characterized. An improvement in these two aspects would allow us to propose different therapeutic strategies aiming to ameliorate and even revert the long-lasting consequences of the IUGR. HYPOTHESIS: We hypothesized that IUGR produces subtle structural brain changes that underlie the long-term neurobehavioral and cognitive impairments. The severity of the neurodevelopmental consequences might be related to the severity of the prenatal insult (reduction in nutrients with or without a reduction in oxygen). High-resolution brain imaging along with specific histological techniques focused on neuronal connectivity could evidence these structural brain changes. Additionally, we hypothesized that an early postnatal stimulation might ameliorate the structural and functional impairments that persist at the long-term period after IUGR. METHODS: Two animal models of IUGR were used in this thesis: i. A cohort of pregnant rabbits was randomized to reproduce an undernutrition model based on maternal food reduction intake, ii. Another cohort of pregnant rabbits was randomized to the placental insufficiency model based on the surgical ligation of 40-50% of the uteroplacental vessels that irrigate each gestational sac. After the delivery in both models, IUGR and controls animals were followed up to the 70th postnatal days. At the 30th postnatal days, a subgroup of IUGR animals was randomized to an environmental enrichment strategy. In all the groups at the neonatal period, general motor skills, reflexes, and olfactory sensitivity were evaluated. Similarly, at the 70th postnatal days, anxiety, memory, and learning were evaluated. Afterward, animals were sacrificed and brains were fixed and diffusion MRI was then performed. In a subset of animals, changes at the microstructural level and differences in the number of fibers in two specific brain circuits (anxiety and memory circuits) were performed by using a Voxel-Based approach (VBA) and Tractography analysis, respectively. Moreover, brain networks were obtained and evaluated by means of a Connectomics. Finally, a subgroup of animals was also histologically evaluated by means of dendritic spine and perineural nets evaluation in the Hippocampus. RESULTS: IUGR animals showed poorer functional performance in both moments, especially in the model of placental insufficiency. At the long-term… Advisors/Committee Members: Universitat de Barcelona. Facultat de Medicina, [email protected] (authoremail), false (authoremailshow), Gratacós Solsona, Eduard (director), Figueras Retuerta, Francesc (director), true (authorsendemail).

Subjects/Keywords: Fetus; Feto; Neurobiologia del desenvolupament; Neurobiología del desarrollo; Developmental neurobiology; Malalties del fetus; Enfermedades fetales; Fetus diseases; Histologia; Histología; Histology; Ciències de la Salut; 618

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APA (6^th Edition):

Illa Armengol, M. (2017). Brain effects of fetal growth restriction and their prevention in an animal model. (Thesis). Universitat de Barcelona. Retrieved from http://hdl.handle.net/10803/565667

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Illa Armengol, Míriam. “Brain effects of fetal growth restriction and their prevention in an animal model.” 2017. Thesis, Universitat de Barcelona. Accessed January 29, 2020. http://hdl.handle.net/10803/565667.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Illa Armengol, Míriam. “Brain effects of fetal growth restriction and their prevention in an animal model.” 2017. Web. 29 Jan 2020.

Vancouver:

Illa Armengol M. Brain effects of fetal growth restriction and their prevention in an animal model. [Internet] [Thesis]. Universitat de Barcelona; 2017. [cited 2020 Jan 29]. Available from: http://hdl.handle.net/10803/565667.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Illa Armengol M. Brain effects of fetal growth restriction and their prevention in an animal model. [Thesis]. Universitat de Barcelona; 2017. Available from: http://hdl.handle.net/10803/565667

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Hong Kong

23. Cheong, Kah-bik. The use of volumetry by three-dimensional ultrasound in the first trimester.

Degree: M. Phil., 2009, University of Hong Kong

URL: Cheong, K. [張嘉碧]. (2009). The use of volumetry by three-dimensional ultrasound in the first trimester. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b4357233 ; http://dx.doi.org/10.5353/th_b4357233 ; http://hdl.handle.net/10722/57007

published_or_final_version

Obstetrics and Gynaecology

Master

Master of Philosophy

Advisors/Committee Members: Ng, EHY.

Subjects/Keywords: Volume (Cubic content); Fetus - Ultrasonic imaging.; Fetus - Abnormalities.

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APA (6^th Edition):

Cheong, K. (2009). The use of volumetry by three-dimensional ultrasound in the first trimester. (Masters Thesis). University of Hong Kong. Retrieved from Cheong, K. [張嘉碧]. (2009). The use of volumetry by three-dimensional ultrasound in the first trimester. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b4357233 ; http://dx.doi.org/10.5353/th_b4357233 ; http://hdl.handle.net/10722/57007

Chicago Manual of Style (16^th Edition):

Cheong, Kah-bik. “The use of volumetry by three-dimensional ultrasound in the first trimester.” 2009. Masters Thesis, University of Hong Kong. Accessed January 29, 2020. Cheong, K. [張嘉碧]. (2009). The use of volumetry by three-dimensional ultrasound in the first trimester. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b4357233 ; http://dx.doi.org/10.5353/th_b4357233 ; http://hdl.handle.net/10722/57007.

MLA Handbook (7^th Edition):

Cheong, Kah-bik. “The use of volumetry by three-dimensional ultrasound in the first trimester.” 2009. Web. 29 Jan 2020.

Vancouver:

Cheong K. The use of volumetry by three-dimensional ultrasound in the first trimester. [Internet] [Masters thesis]. University of Hong Kong; 2009. [cited 2020 Jan 29]. Available from: Cheong, K. [張嘉碧]. (2009). The use of volumetry by three-dimensional ultrasound in the first trimester. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b4357233 ; http://dx.doi.org/10.5353/th_b4357233 ; http://hdl.handle.net/10722/57007.

Council of Science Editors:

Cheong K. The use of volumetry by three-dimensional ultrasound in the first trimester. [Masters Thesis]. University of Hong Kong; 2009. Available from: Cheong, K. [張嘉碧]. (2009). The use of volumetry by three-dimensional ultrasound in the first trimester. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b4357233 ; http://dx.doi.org/10.5353/th_b4357233 ; http://hdl.handle.net/10722/57007

University of Hong Kong

24. 林勇行; Lam, Yung-hang. Sonographic features of fetuses with homozygous [alpha]-thalassaemia-1during early pregnancy.

Degree: Doctor of Medicine, 2001, University of Hong Kong

URL: Lam, Y. [林勇行]. (2001). Sonographic features of fetuses with homozygous [alpha]-thalassaemia-1 during early pregnancy. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b3198174 ; http://dx.doi.org/10.5353/th_b3198174 ; http://hdl.handle.net/10722/27883

published_or_final_version

Medicine

Master

Doctor of Medicine

Subjects/Keywords: Thalassemia.; Fetus - Ultrasonic imaging.; Fetus - Diseases - Diagnosis.; Pregnancy - Complications.

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APA (6^th Edition):

林勇行; Lam, Y. (2001). Sonographic features of fetuses with homozygous [alpha]-thalassaemia-1during early pregnancy. (Doctoral Dissertation). University of Hong Kong. Retrieved from Lam, Y. [林勇行]. (2001). Sonographic features of fetuses with homozygous [alpha]-thalassaemia-1 during early pregnancy. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b3198174 ; http://dx.doi.org/10.5353/th_b3198174 ; http://hdl.handle.net/10722/27883

Chicago Manual of Style (16^th Edition):

林勇行; Lam, Yung-hang. “Sonographic features of fetuses with homozygous [alpha]-thalassaemia-1during early pregnancy.” 2001. Doctoral Dissertation, University of Hong Kong. Accessed January 29, 2020. Lam, Y. [林勇行]. (2001). Sonographic features of fetuses with homozygous [alpha]-thalassaemia-1 during early pregnancy. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b3198174 ; http://dx.doi.org/10.5353/th_b3198174 ; http://hdl.handle.net/10722/27883.

MLA Handbook (7^th Edition):

林勇行; Lam, Yung-hang. “Sonographic features of fetuses with homozygous [alpha]-thalassaemia-1during early pregnancy.” 2001. Web. 29 Jan 2020.

Vancouver:

林勇行; Lam Y. Sonographic features of fetuses with homozygous [alpha]-thalassaemia-1during early pregnancy. [Internet] [Doctoral dissertation]. University of Hong Kong; 2001. [cited 2020 Jan 29]. Available from: Lam, Y. [林勇行]. (2001). Sonographic features of fetuses with homozygous [alpha]-thalassaemia-1 during early pregnancy. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b3198174 ; http://dx.doi.org/10.5353/th_b3198174 ; http://hdl.handle.net/10722/27883.

Council of Science Editors:

林勇行; Lam Y. Sonographic features of fetuses with homozygous [alpha]-thalassaemia-1during early pregnancy. [Doctoral Dissertation]. University of Hong Kong; 2001. Available from: Lam, Y. [林勇行]. (2001). Sonographic features of fetuses with homozygous [alpha]-thalassaemia-1 during early pregnancy. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b3198174 ; http://dx.doi.org/10.5353/th_b3198174 ; http://hdl.handle.net/10722/27883

University of Florida

25. Maynard, Matthew R. Hybrid Computational Phantoms of the Developing Fetus and Pregnant Female Construction and Application to Select Internal Radiation Dosimetry Studies.

Degree: PhD, Biomedical Engineering, 2013, University of Florida

URL: http://ufdc.ufl.edu/UFE0045953

► The developing human fetus is sensitive to ionizing radiation and can experience a number of deleterious health effects following radiation exposure. Although not as immediately… (more)

▼ The developing human fetus is sensitive to ionizing radiation and can experience a number of deleterious health effects following radiation exposure. Although not as immediately severe as many possible health effects, radiation-induced cancer nevertheless represents an important risk, particularly for studies such as to the European Union's Epidemiological Studies of Exposed Southern Urals Populations (SOLO) project, which investigates long-term health effects from protracted radiation exposures. For such studies, dose estimates for individual organs are required in order to mathematically quantify organ-specific health risks. One method to estimate fetal radiation doses associated with in utero exposures is by computationally simulating irradiation events using virtual replicas of the pregnant female and her fetus. First, several series of anatomically-detailed computational phantoms were constructed to represent the pregnant mother and fetus of the Western and Russian Urals populations. Second,through computational simulations performed on these phantoms, a comprehensive set of fetal radiation dose coefficients (S-values), which correlate internal radiation activity in source organs with absorbed doses in target organs, was calculated for radionuclides of interest to SOLO. Among all fetal ages, S-values ranged in magnitude from ~10-14 to ~10-10 Gy-Bq-1-s-1 for fetal source organs and from ~10-18 to ~10-14 Gy-Bq-1-s-1 for maternal source organs, depending on particle type, particle energy and fetal age. For a given radionuclide and fetal age, S-values for fetal source organs were approximately two orders of magnitude larger than for maternal source organs. Little variation in S-value was observed among fetal source organs, while variations of over 100% with respect to the mean were observed for maternal source organs near the fetus. S-value variations from maternal source organs were highly dependent on the position of the fetus and separation distance from the source organ. The computational phantoms developed in this work provide novel pathways for assessing fetal radiation dosimetry at the level of individual organs. This anatomical resolution is critical for dose tracking and cancer risk estimates associated with various radiation exposures,including non-medical sources such as those involving the SOLO cohorts and Japanese atomic bomb survivors as well as medically-administered radiation from procedures such as computed tomography (CT). ( en ) Advisors/Committee Members: Bolch, Wesley Emmett (committee chair), Hintenlang, David Eric (committee member), Aris, John Phillip (committee member), Tillman, Mark D (committee member), Shifrin, Roger Yale (committee member), Moawad, Nashat Sayed (committee member).

Subjects/Keywords: Body tissues; Bones; Cranium; Dosage; Fetus; Gestational age; Human organs; Radionuclides; Reproduction; Vertebrae; female – fetus – phantom – pregnant – radiation – solo – urals

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APA (6^th Edition):

Maynard, M. R. (2013). Hybrid Computational Phantoms of the Developing Fetus and Pregnant Female Construction and Application to Select Internal Radiation Dosimetry Studies. (Doctoral Dissertation). University of Florida. Retrieved from http://ufdc.ufl.edu/UFE0045953

Chicago Manual of Style (16^th Edition):

Maynard, Matthew R. “Hybrid Computational Phantoms of the Developing Fetus and Pregnant Female Construction and Application to Select Internal Radiation Dosimetry Studies.” 2013. Doctoral Dissertation, University of Florida. Accessed January 29, 2020. http://ufdc.ufl.edu/UFE0045953.

MLA Handbook (7^th Edition):

Maynard, Matthew R. “Hybrid Computational Phantoms of the Developing Fetus and Pregnant Female Construction and Application to Select Internal Radiation Dosimetry Studies.” 2013. Web. 29 Jan 2020.

Vancouver:

Maynard MR. Hybrid Computational Phantoms of the Developing Fetus and Pregnant Female Construction and Application to Select Internal Radiation Dosimetry Studies. [Internet] [Doctoral dissertation]. University of Florida; 2013. [cited 2020 Jan 29]. Available from: http://ufdc.ufl.edu/UFE0045953.

Council of Science Editors:

Maynard MR. Hybrid Computational Phantoms of the Developing Fetus and Pregnant Female Construction and Application to Select Internal Radiation Dosimetry Studies. [Doctoral Dissertation]. University of Florida; 2013. Available from: http://ufdc.ufl.edu/UFE0045953

University of Florida

26. Perrone, Dana. The Role of the Mineralocorticoid Receptor in the Hypothalamic-Pituitary-Adrenal Axis in Fetal Life.

Degree: 2010, University of Florida

URL: http://ufdc.ufl.edu/AA00059994

► The development of the HPA axis is especially important in neonatal heath. In the fetus, the release of glucocorticoids stimulates the maturation of organs and… (more)

Subjects/Keywords: Corticosteroids; Fetus; Glucocorticoids; Hypothalamus; Messenger RNA; Mineralocorticoid receptors; Polymerase chain reaction; Pregnancy; Receptors; Sheep; Fetus – Development; Hypothalamic-pituitary-adrenal axis; Mineralocorticoids

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APA (6^th Edition):

Perrone, D. (2010). The Role of the Mineralocorticoid Receptor in the Hypothalamic-Pituitary-Adrenal Axis in Fetal Life. (Thesis). University of Florida. Retrieved from http://ufdc.ufl.edu/AA00059994

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Perrone, Dana. “The Role of the Mineralocorticoid Receptor in the Hypothalamic-Pituitary-Adrenal Axis in Fetal Life.” 2010. Thesis, University of Florida. Accessed January 29, 2020. http://ufdc.ufl.edu/AA00059994.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Perrone, Dana. “The Role of the Mineralocorticoid Receptor in the Hypothalamic-Pituitary-Adrenal Axis in Fetal Life.” 2010. Web. 29 Jan 2020.

Vancouver:

Perrone D. The Role of the Mineralocorticoid Receptor in the Hypothalamic-Pituitary-Adrenal Axis in Fetal Life. [Internet] [Thesis]. University of Florida; 2010. [cited 2020 Jan 29]. Available from: http://ufdc.ufl.edu/AA00059994.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Perrone D. The Role of the Mineralocorticoid Receptor in the Hypothalamic-Pituitary-Adrenal Axis in Fetal Life. [Thesis]. University of Florida; 2010. Available from: http://ufdc.ufl.edu/AA00059994

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universitat de Barcelona

27. Comas Rovira, Montserrat. Cardiac dysfunction by tissue doppler in earty-and late-onset fetal growth restriction.

Degree: Departament d'Obstetrícia i Ginecologia, Pediatria i Radiologia i Medicina Física, 2011, Universitat de Barcelona

URL: http://hdl.handle.net/10803/51517

► SUMMARY 1) Background Fetal growth restriction (FGR) is present in 5-10% of the pregnancies and is associated to high perinatal and long-term cardiovascular morbidity. Subclinical… (more)

Subjects/Keywords: Medicina prenatal; Prenatal Medicine; Malalties del fetus; Enfermedades fetales; Fetus – Diseases; Ciències de la Salut; 618

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APA (6^th Edition):

Comas Rovira, M. (2011). Cardiac dysfunction by tissue doppler in earty-and late-onset fetal growth restriction. (Thesis). Universitat de Barcelona. Retrieved from http://hdl.handle.net/10803/51517

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Comas Rovira, Montserrat. “Cardiac dysfunction by tissue doppler in earty-and late-onset fetal growth restriction.” 2011. Thesis, Universitat de Barcelona. Accessed January 29, 2020. http://hdl.handle.net/10803/51517.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Comas Rovira, Montserrat. “Cardiac dysfunction by tissue doppler in earty-and late-onset fetal growth restriction.” 2011. Web. 29 Jan 2020.

Vancouver:

Comas Rovira M. Cardiac dysfunction by tissue doppler in earty-and late-onset fetal growth restriction. [Internet] [Thesis]. Universitat de Barcelona; 2011. [cited 2020 Jan 29]. Available from: http://hdl.handle.net/10803/51517.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Comas Rovira M. Cardiac dysfunction by tissue doppler in earty-and late-onset fetal growth restriction. [Thesis]. Universitat de Barcelona; 2011. Available from: http://hdl.handle.net/10803/51517

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

28. Shipp, Darlene. Effects of Perceived Fetal Movement and Fetal Ultrasound Imagery on Maternal-Fetal Attachment .

Degree: 1992, Drake U

URL: http://hdl.handle.net/2092/539

► The purpose of the study was to examine the effects of perceived fetal movement and/or viewing of the fetus by the pregnant woman via ultrasonography… (more)

Subjects/Keywords: Fetus – Movements; Fetus – Ultrasonic imaging; Attachment behavior

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Shipp, D. (1992). Effects of Perceived Fetal Movement and Fetal Ultrasound Imagery on Maternal-Fetal Attachment . (Thesis). Drake U. Retrieved from http://hdl.handle.net/2092/539

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Shipp, Darlene. “Effects of Perceived Fetal Movement and Fetal Ultrasound Imagery on Maternal-Fetal Attachment .” 1992. Thesis, Drake U. Accessed January 29, 2020. http://hdl.handle.net/2092/539.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Shipp, Darlene. “Effects of Perceived Fetal Movement and Fetal Ultrasound Imagery on Maternal-Fetal Attachment .” 1992. Web. 29 Jan 2020.

Vancouver:

Shipp D. Effects of Perceived Fetal Movement and Fetal Ultrasound Imagery on Maternal-Fetal Attachment . [Internet] [Thesis]. Drake U; 1992. [cited 2020 Jan 29]. Available from: http://hdl.handle.net/2092/539.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Shipp D. Effects of Perceived Fetal Movement and Fetal Ultrasound Imagery on Maternal-Fetal Attachment . [Thesis]. Drake U; 1992. Available from: http://hdl.handle.net/2092/539

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

The Ohio State University

29. Dennis, Richard Andrew. The development of the immune response of the fetal dog .

Degree: PhD, Graduate School, 1968, The Ohio State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1486647101628514

Subjects/Keywords: Health Sciences; Immunology; Fetus

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Dennis, R. A. (1968). The development of the immune response of the fetal dog . (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1486647101628514

Chicago Manual of Style (16^th Edition):

Dennis, Richard Andrew. “The development of the immune response of the fetal dog .” 1968. Doctoral Dissertation, The Ohio State University. Accessed January 29, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1486647101628514.

MLA Handbook (7^th Edition):

Dennis, Richard Andrew. “The development of the immune response of the fetal dog .” 1968. Web. 29 Jan 2020.

Vancouver:

Dennis RA. The development of the immune response of the fetal dog . [Internet] [Doctoral dissertation]. The Ohio State University; 1968. [cited 2020 Jan 29]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1486647101628514.

Council of Science Editors:

Dennis RA. The development of the immune response of the fetal dog . [Doctoral Dissertation]. The Ohio State University; 1968. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1486647101628514

30. Bernardes, Lisandra Stein. Análise da vascularização renal ao Power Doppler tridimensional em fetos com dilatação de vias urinárias: correlação com prognóstico renal pós-natal.

Degree: PhD, Obstetrícia e Ginecologia, 2011, University of São Paulo

URL: http://www.teses.usp.br/teses/disponiveis/5/5139/tde-18022011-124911/ ;

► INTRODUÇÃO: Não há, até o momento, método ideal de avaliação da função renal em fetos com dilatação de vias urinárias. A ultrassonografia é utilizada como… (more)

▼ INTRODUÇÃO: Não há, até o momento, método ideal de avaliação da função renal em fetos com dilatação de vias urinárias. A ultrassonografia é utilizada como um método não invasivo e alguns parâmetros, como o índice de líquido amniótico, foram descritos na predição de insuficiência renal. Entretanto, a sensibilidade é baixa e a detecção de alterações, muitas vezes, ocorre tardiamente na gestação. A avaliação bioquímica da urina ou sangue fetais acrescenta risco à gestação e, apesar de melhorar a detecção de insuficiência renal, tem sensibilidade e especificidade baixas. O Power Doppler tridimensional é um método capaz de quantificar fluxo em órgãos parenquimatosos e tem sido utilizado na quantificação de fluxo sanguíneo de órgãos fetais e placenta. Como fetos com obstrução de vias urinárias e insuficiência renal apresentam diminuição no número de glomérulos, a quantificação do fluxo renal ao Power Doppler tridimensional poderia aprimorar a avaliação da função renal desses fetos. OBJETIVOS: quantificar o fluxo renal ao Power Doppler tridimensional em fetos com suspeita de obstrução de vias urinárias e naqueles com morfologia renal normal, avaliar a influência da profundidade nos índices vasculares e comparar os índices nos fetos que evoluíram com e sem insuficiência renal no período pós-natal. MÉTODOS: fetos com hidronefrose bilateral e/ou dilatação vesical foram prospectivamente comparados com fetos sem malformações em relação à quantificação do fluxo renal ao Power Doppler tridimensional. Os parâmetros avaliados foram IV, IVF, IF e a profundidade. Após o nascimento, as crianças foram seguidas por uma equipe de nefrologia e urologia e, de acordo com a função renal, foram classificadas em 2 grupos: insuficiência renal e função renal normal. A vascularização renal foi avaliada em cada grupo e comparada ao grupo controle. RESULTADOS: vinte e três fetos com dilatação de vias urinárias e setenta e três com morfologia renal normal foram considerados para a análise estatística. Cinco crianças (21,7%) apresentaram insuficiência renal após o nascimento. IV e IVF foram significativamente mais baixos nos casos que apresentaram insuficiência renal do que naqueles com função renal normal (p=0,009 e 0,036, respectivamente). Os três índices corrigidos pela profundidade (IVCP, IFCP e IVFCP) variaram com a idade gestacional e a variação inter-observador melhorou quando eles foram utilizados. A porcentagem do IVCP e do IVFCP em relação à controles de mesma idade gestacional foi menor nos casos que desenvolveram insuficiência renal do que naqueles que evoluíram com função renal normal. CONCLUSÕES: IV e IVF foram significativamente mais baixos em fetos que evoluíram com insuficiência renal pósnatal, porém a profundidade foi um fator interferente importante. Desta forma, IVCP e IVFCP são potencialmente melhores na avaliação de fetos com suspeita de obstrução de vias urinárias. Como os índices corrigidos pela profundidade variam de acordo com a idade gestacional, é necessária a construção de curvas de normalidade por idade gestacional para… Advisors/Committee Members: Ruano, Rodrigo.

Subjects/Keywords: Feto; Fetus; Hidronefrose; Hydronephrosis; Insuficiência renal; Renal insufficiency; Ultrassonografia; Ultrassonography

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Bernardes, L. S. (2011). Análise da vascularização renal ao Power Doppler tridimensional em fetos com dilatação de vias urinárias: correlação com prognóstico renal pós-natal. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/5/5139/tde-18022011-124911/ ;

Chicago Manual of Style (16^th Edition):

Bernardes, Lisandra Stein. “Análise da vascularização renal ao Power Doppler tridimensional em fetos com dilatação de vias urinárias: correlação com prognóstico renal pós-natal.” 2011. Doctoral Dissertation, University of São Paulo. Accessed January 29, 2020. http://www.teses.usp.br/teses/disponiveis/5/5139/tde-18022011-124911/ ;.

MLA Handbook (7^th Edition):

Bernardes, Lisandra Stein. “Análise da vascularização renal ao Power Doppler tridimensional em fetos com dilatação de vias urinárias: correlação com prognóstico renal pós-natal.” 2011. Web. 29 Jan 2020.

Vancouver:

Bernardes LS. Análise da vascularização renal ao Power Doppler tridimensional em fetos com dilatação de vias urinárias: correlação com prognóstico renal pós-natal. [Internet] [Doctoral dissertation]. University of São Paulo; 2011. [cited 2020 Jan 29]. Available from: http://www.teses.usp.br/teses/disponiveis/5/5139/tde-18022011-124911/ ;.

Council of Science Editors:

Bernardes LS. Análise da vascularização renal ao Power Doppler tridimensional em fetos com dilatação de vias urinárias: correlação com prognóstico renal pós-natal. [Doctoral Dissertation]. University of São Paulo; 2011. Available from: http://www.teses.usp.br/teses/disponiveis/5/5139/tde-18022011-124911/ ;

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