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1.
Chabala, Freeman W.
Likelihood of development renal dysfunction after one year of treatment with tenofovir(TDF) in HIV/AIDS patients at the UTH: An analytical cross-section study.
Degree: 2015, University of Zimbabwe
URL: http://dspace.unza.zm/handle/123456789/3787
► Studies have suggested that Sub-Sahara Africans are prone to HIV-related renal dysfunction. A study done in Zambia showed increased deaths among HIV/AIDS patients who had…
(more)
▼ Studies have suggested that Sub-Sahara Africans are prone to HIV-related renal dysfunction. A study done in Zambia showed increased deaths among HIV/AIDS patients who had renal dysfunction. Tenofovir Disoproxil Fumarate (TDF) one of the first line antiretroviral drugs in Zambia, has been associated with renal tubulopathy and nephrotoxicity in many studies. In Zambia, TDF has been in use since 2007. This study was set out to determine whether TDF had similar Nephrotoxic effects in patients receiving TDF- based regimen at the largest Antiretroviral Therapy (ART) Centre in Lusaka. It aimed at determining the likelihood of patients with no renal dysfunction (CLcr method) at initiation of therapy developing renal dysfunction after 1 year of treatment with TDF- based regimen compared to those on non- TDF- based regimen (these patients were either on Stavudine (D4T)- based regimen or Zidovudine (AZT)- based regimen).
An analytical cross- sectional study involved analysis of data obtained from 549 randomly selected HIV/AIDS patient files that were started on ART between September, 2007 and January, 2013. Out of the 549 patients, 275 patients were on TDF- based regimen and 274 patients were on non- TDF- based regimen.
Findings showed a significantly larger number of participants on TDF developing renal dysfunction from having no renal dysfunction at baseline compared to those on non- TDF- based regimen; 51 out of 180 verses 8 out of 207, P< 0.001. Upon controlling for age and sex, logistic regression model showed that HIV/AIDS patients on TDF- based regimen were 8.77 times more likely to develop renal dysfunction after one year of therapy from having no renal dysfunction at baseline compared to those on non- TDF- based regimen.
It was concluded that treatment with TDF- based regimen was strongly associated with developing renal dysfunction after 1 year of treatment compared to non TDF- based regimen. There is need for follow up of patients on TDF- based regimen or therapy modification to reduce cases of renal dysfunction in patients on treatment thereby allowing them benefit fully by the treatment.
Subjects/Keywords: Renal Failure; Kidney Failure
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APA (6th Edition):
Chabala, F. W. (2015). Likelihood of development renal dysfunction after one year of treatment with tenofovir(TDF) in HIV/AIDS patients at the UTH: An analytical cross-section study. (Thesis). University of Zimbabwe. Retrieved from http://dspace.unza.zm/handle/123456789/3787
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Chabala, Freeman W. “Likelihood of development renal dysfunction after one year of treatment with tenofovir(TDF) in HIV/AIDS patients at the UTH: An analytical cross-section study.” 2015. Thesis, University of Zimbabwe. Accessed January 23, 2021.
http://dspace.unza.zm/handle/123456789/3787.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Chabala, Freeman W. “Likelihood of development renal dysfunction after one year of treatment with tenofovir(TDF) in HIV/AIDS patients at the UTH: An analytical cross-section study.” 2015. Web. 23 Jan 2021.
Vancouver:
Chabala FW. Likelihood of development renal dysfunction after one year of treatment with tenofovir(TDF) in HIV/AIDS patients at the UTH: An analytical cross-section study. [Internet] [Thesis]. University of Zimbabwe; 2015. [cited 2021 Jan 23].
Available from: http://dspace.unza.zm/handle/123456789/3787.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Chabala FW. Likelihood of development renal dysfunction after one year of treatment with tenofovir(TDF) in HIV/AIDS patients at the UTH: An analytical cross-section study. [Thesis]. University of Zimbabwe; 2015. Available from: http://dspace.unza.zm/handle/123456789/3787
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Alberta
2.
Dewart, Krista D.
Impact of Recall Visits on Hospitlaization Rates in a Heart
Failure Clinic.
Degree: Master of Nursing, Faculty of Nursing, 2014, University of Alberta
URL: https://era.library.ualberta.ca/files/707957863
► Many heart failure (HF) hospital admissions are avoidable with appropriate surveillance and self-care support that HF Clinics can provide. Previous studies conducted vary in approach…
(more)
▼ Many heart failure (HF) hospital admissions are
avoidable with appropriate surveillance and self-care support that
HF Clinics can provide. Previous studies conducted vary in approach
to surveillance. The goal of this study was to assess the impact of
frequency of HF Clinic recall visits on hospital admissions. A
retrospective cohort of 110 patients enrolled in a HF Clinic was
selected. Correlations were conducted among demographic
characteristics, clinical variables, number of recall visits, and
hospital admission rates. Significant variables were entered into
multivariate regression analysis to determine predictors of
frequency of recall visits and hospital admissions. HF clinic visit
recall frequency was not predictive of hospitalization rates in
this cohort. The main predictor of hospital admissions was the
baseline Seattle Heart Failure Model score. Additional study of
this composite score as a potential tool for determining HF Clinic
recall frequency is required.
Subjects/Keywords: Heart Failure
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APA ·
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APA (6th Edition):
Dewart, K. D. (2014). Impact of Recall Visits on Hospitlaization Rates in a Heart
Failure Clinic. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/707957863
Chicago Manual of Style (16th Edition):
Dewart, Krista D. “Impact of Recall Visits on Hospitlaization Rates in a Heart
Failure Clinic.” 2014. Masters Thesis, University of Alberta. Accessed January 23, 2021.
https://era.library.ualberta.ca/files/707957863.
MLA Handbook (7th Edition):
Dewart, Krista D. “Impact of Recall Visits on Hospitlaization Rates in a Heart
Failure Clinic.” 2014. Web. 23 Jan 2021.
Vancouver:
Dewart KD. Impact of Recall Visits on Hospitlaization Rates in a Heart
Failure Clinic. [Internet] [Masters thesis]. University of Alberta; 2014. [cited 2021 Jan 23].
Available from: https://era.library.ualberta.ca/files/707957863.
Council of Science Editors:
Dewart KD. Impact of Recall Visits on Hospitlaization Rates in a Heart
Failure Clinic. [Masters Thesis]. University of Alberta; 2014. Available from: https://era.library.ualberta.ca/files/707957863

Texas A&M University
3.
Zambrano, Orlando.
Error-in-variables for failure criteria applied to the near -wellbore region.
Degree: PhD, Petroleum Engineering, 2004, Texas A&M University
URL: http://hdl.handle.net/1969.1/196
► The development of a methodology to improve the parametric representation of the failure criteria used to characterize rock strength of a reservoir rock in the…
(more)
▼ The development of a methodology to improve the parametric representation of the
failure criteria used to characterize rock strength of a reservoir rock in the near-wellbore region is the focus of this study. We adopted a statistical method, so-called error-in-variables (EIV), to take into account experimental errors in all of the measured variables. The proposed methodology is employed to obtain the parameters of the
failure envelope (2D criteria) from experimental data in the following cases:
When the experimental data are used directly to determine the
failure envelope in the Mohr plane. When a
failure envelope is first obtained in the principal-stress plane and then transformed into the Mohr plane using Computer Algebra. When the presence of pore fluid requires the consideration of effective stresses. When the brittle-ductile transition requires special form of the envelope (cap models) Using generalization of previously developed methods, we employed EIV methods to obtain the parameters of a
failure surface in the principal-stress space (3D criteria).The basic hypothesis of this work is that the EIV method provides a better representation of
failure criteria than the previous methodology. The basic application of any
failure criterion is to determine whether a certain stress state will or will not lead to
failure. A parametric representation is considered better than another if the likelihood of obtaining the wrong answer is less than in the other case. Therefore, the best representation (within a certain family of envelopes or surfaces) is the one minimizing the objective function, which is nothing else but the likelihood of this wrong answer. To test the basic hypothesis of this work, I compared the objective function (likelihood of erroneous decision) calculated with parametric representations obtained by various methods. To achieve this I evaluated a well-documented, published set of experimental data, for which
failure envelopes have been fitted by other methods. This work is limited to the processing of data obtained in experiments conducted in homogenous, isotropic rock at isothermal conditions. Sedimentary rocks such as sandstone are the focus of this study because of their importance in near-wellbore reservoir rock stability problems. Nevertheless, the methodology developed in this work is not limited to this type of rock.
Advisors/Committee Members: Valko, Peter P. (advisor), Russell, James E. (advisor), Ikelle, Luc T. (committee member), Blasingame, Thomas A. (committee member).
Subjects/Keywords: failure
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Zambrano, O. (2004). Error-in-variables for failure criteria applied to the near -wellbore region. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/196
Chicago Manual of Style (16th Edition):
Zambrano, Orlando. “Error-in-variables for failure criteria applied to the near -wellbore region.” 2004. Doctoral Dissertation, Texas A&M University. Accessed January 23, 2021.
http://hdl.handle.net/1969.1/196.
MLA Handbook (7th Edition):
Zambrano, Orlando. “Error-in-variables for failure criteria applied to the near -wellbore region.” 2004. Web. 23 Jan 2021.
Vancouver:
Zambrano O. Error-in-variables for failure criteria applied to the near -wellbore region. [Internet] [Doctoral dissertation]. Texas A&M University; 2004. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/1969.1/196.
Council of Science Editors:
Zambrano O. Error-in-variables for failure criteria applied to the near -wellbore region. [Doctoral Dissertation]. Texas A&M University; 2004. Available from: http://hdl.handle.net/1969.1/196
4.
Budrewicz, Jay.
Novel Heart Failure Model Development in Swine.
Degree: Biomedical Engineering, 2017, Brown University
URL: https://repository.library.brown.edu/studio/item/bdr:733284/
► Abstract of Novel Heart Failure Development in Swine, by Jay Budrewicz, ScM., Brown University, May 2017. Objective: There is a need for a simple and…
(more)
▼ Abstract of Novel Heart
Failure Development in Swine,
by Jay Budrewicz, ScM., Brown University, May 2017. Objective:
There is a need for a simple and reliable large animal doxorubicin
cardiotoxicity heart
failure model that is created through similar
means as it is caused in humans. The model is necessary for the
testing of novel and existing drugs and medical devices used to
treat this condition. Methods: Two juvenile Yorkshire swine were
administered different doses per body mass (30mg/m2 and 3mg/m2) of
a doxorubicin hydrogel. It was serially delivered, percutaneously
through the sub-xyphoid region, to the pericardial sac. The
doxorubicin hydrogel was formulated to become viscous and remain in
the pericardium following weekly administrations. Transesophageal
Echocardiography Data, hemodynamic data and general health data
were collected to evaluate the effects of the toxin. At necropsy
evidence of macroscopic findings were collected and processed for
histological examination. Results: The animal that received the
30mg/m2 dose displayed clinical observations (dyspnea and wet
cough) that prevented it from surviving for more than two
administrations or reaching the intended 42 day time point. This
animal had a left ventricular ejection fraction that decreased from
56 to 23%. Histological observations of the left atrium showed
evidence of fibrous exudates in the pericardium. In the myocardium
of the left atrium, there was a zone of superficial myocardial
pallor-degeneration. The animal that received the 3mg/m2 dose did
not exhibit any signs of doxorubicin induced heart
failure.
Conclusion: The two doses tested in this doxorubicin induced heart
failure model development appear to be too high and two low. The
30mg/m2 dose resulted in off target cardiotoxicity described as
pericarditis/epicarditis combined with pericardial effusion
resulting in right sided heart
failure. The 3mg/m2 did not result
in any significant cardiotoxicity. Doses in between the two tested
for this model need to be used in an attempt to identify the right
dose that will be successful in creating the desired
toxicity.
Advisors/Committee Members: Mathiowitz, Edith (Advisor), Schell, Jacquelyn (Reader), Scott, Jeffrey (Reader).
Subjects/Keywords: Heart failure
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Budrewicz, J. (2017). Novel Heart Failure Model Development in Swine. (Thesis). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:733284/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Budrewicz, Jay. “Novel Heart Failure Model Development in Swine.” 2017. Thesis, Brown University. Accessed January 23, 2021.
https://repository.library.brown.edu/studio/item/bdr:733284/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Budrewicz, Jay. “Novel Heart Failure Model Development in Swine.” 2017. Web. 23 Jan 2021.
Vancouver:
Budrewicz J. Novel Heart Failure Model Development in Swine. [Internet] [Thesis]. Brown University; 2017. [cited 2021 Jan 23].
Available from: https://repository.library.brown.edu/studio/item/bdr:733284/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Budrewicz J. Novel Heart Failure Model Development in Swine. [Thesis]. Brown University; 2017. Available from: https://repository.library.brown.edu/studio/item/bdr:733284/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Wake Forest University
5.
Christensen, Brittany.
Examining the Role of Body Mass Index in Heart Failure with a Preserved Ejection Fraction: Is there an Obesity Phenotype?.
Degree: 2019, Wake Forest University
URL: http://hdl.handle.net/10339/93983
Although preliminary research suggests there may be an obese HFpEF phenotype, the purpose of this investigation was to examine the impact of BMI status on four key domains of HFpEF; plasma neurohormone levels, health related quality of life (HRQOL), exercise capacity, and LV function.
Subjects/Keywords: heart failure
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Christensen, B. (2019). Examining the Role of Body Mass Index in Heart Failure with a Preserved Ejection Fraction: Is there an Obesity Phenotype?. (Thesis). Wake Forest University. Retrieved from http://hdl.handle.net/10339/93983
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Christensen, Brittany. “Examining the Role of Body Mass Index in Heart Failure with a Preserved Ejection Fraction: Is there an Obesity Phenotype?.” 2019. Thesis, Wake Forest University. Accessed January 23, 2021.
http://hdl.handle.net/10339/93983.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Christensen, Brittany. “Examining the Role of Body Mass Index in Heart Failure with a Preserved Ejection Fraction: Is there an Obesity Phenotype?.” 2019. Web. 23 Jan 2021.
Vancouver:
Christensen B. Examining the Role of Body Mass Index in Heart Failure with a Preserved Ejection Fraction: Is there an Obesity Phenotype?. [Internet] [Thesis]. Wake Forest University; 2019. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/10339/93983.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Christensen B. Examining the Role of Body Mass Index in Heart Failure with a Preserved Ejection Fraction: Is there an Obesity Phenotype?. [Thesis]. Wake Forest University; 2019. Available from: http://hdl.handle.net/10339/93983
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Manitoba
6.
Figueiredo Pereira De Faria, Ane Cristina.
The utility of state fragility indicators as measures of state failure.
Degree: Political Studies, 2017, University of Manitoba
URL: http://hdl.handle.net/1993/32428
► The state, as an organizational actor, holds an important role in the national sphere as a provider of public goods (social contract), and when it…
(more)
▼ The state, as an organizational actor, holds an important role in the national sphere as a provider of public goods (social contract), and when it fails to do so, it is seen as state
failure. This
failure is conceptualized along a general spectrum from weak, failed, to collapsed. This analysis examines the theoretical concepts of state
failure and the utility of labelling states along this spectrum. The literature overview shows that there is generally agreement that state
failure is a linear process, and it is conceptualized in terms of stages. However, there is a distinct conceptual disagreement on the definition of the stages among scholars, as well as key indicators to measure state
failure. An examination of the four dominant datasets indicates that they and their comparative results provide little basis for classifying states of value for decision-makers contemplating intervention in some form or other. Future research, theoretical, conceptual and empirical is needed to provide a basis for evaluating the most useful tools or options for intervention along the process of state
failure.
Advisors/Committee Members: Fergusson, James (Political Studies) (supervisor), Rounce, Andrea (Political Studies) Byrne, Sean (Peace and Conflict Studies) (examiningcommittee).
Subjects/Keywords: State failure
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Figueiredo Pereira De Faria, A. C. (2017). The utility of state fragility indicators as measures of state failure. (Masters Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/32428
Chicago Manual of Style (16th Edition):
Figueiredo Pereira De Faria, Ane Cristina. “The utility of state fragility indicators as measures of state failure.” 2017. Masters Thesis, University of Manitoba. Accessed January 23, 2021.
http://hdl.handle.net/1993/32428.
MLA Handbook (7th Edition):
Figueiredo Pereira De Faria, Ane Cristina. “The utility of state fragility indicators as measures of state failure.” 2017. Web. 23 Jan 2021.
Vancouver:
Figueiredo Pereira De Faria AC. The utility of state fragility indicators as measures of state failure. [Internet] [Masters thesis]. University of Manitoba; 2017. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/1993/32428.
Council of Science Editors:
Figueiredo Pereira De Faria AC. The utility of state fragility indicators as measures of state failure. [Masters Thesis]. University of Manitoba; 2017. Available from: http://hdl.handle.net/1993/32428

University of Debrecen
7.
Nagy, Melinda.
Intercultural Pragmatic Failure
.
Degree: DE – TEK – Bölcsészettudományi Kar, 2013, University of Debrecen
URL: http://hdl.handle.net/2437/170508
► The goal of this essay is to gain insight to both what exactly pragmatics is and how it might be important or how it might…
(more)
▼ The goal of this essay is to gain insight to both what exactly pragmatics is and how it
might be important or how it might be rather indistinct to semantics (and other linguistic
fields). Further in elaborating or defining pragmatic meaning, this in turn along with a fuller
understanding of culture can better help to isolate cross-cultural pragmatic
failure from other
types of communication
failure. Finally, I attempt to answer how to help students to be better
equipped in avoiding cross-cultural communication problems that which may be more related
to individual character and beliefs.
Advisors/Committee Members: Furkó, Péter (advisor).
Subjects/Keywords: pragmatic failure;
sociopragmatic failure;
politeness;
culture
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Nagy, M. (2013). Intercultural Pragmatic Failure
. (Thesis). University of Debrecen. Retrieved from http://hdl.handle.net/2437/170508
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Nagy, Melinda. “Intercultural Pragmatic Failure
.” 2013. Thesis, University of Debrecen. Accessed January 23, 2021.
http://hdl.handle.net/2437/170508.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Nagy, Melinda. “Intercultural Pragmatic Failure
.” 2013. Web. 23 Jan 2021.
Vancouver:
Nagy M. Intercultural Pragmatic Failure
. [Internet] [Thesis]. University of Debrecen; 2013. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/2437/170508.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Nagy M. Intercultural Pragmatic Failure
. [Thesis]. University of Debrecen; 2013. Available from: http://hdl.handle.net/2437/170508
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Minnesota
8.
LaGarde, Michelle.
The morphodynamic influence of base-level change and waves on lake sediment.
Degree: MS, Earth Sciences, 2018, University of Minnesota
URL: http://hdl.handle.net/11299/201726
► Lakes continuously accumulate sediment, a process that has been ongoing since their formation. The sediment consists of soil particles and biological remains that runoff from…
(more)
▼ Lakes continuously accumulate sediment, a process that has been ongoing since their formation. The sediment consists of soil particles and biological remains that runoff from the watershed and into the lake. The sediment may also contain particles from aeolian transported material from the “airshed” and biological and inorganic precipitated minerals. Thus, lake sediment is a continuous environmental archive, containing information about the history of the lake, and its surroundings. Unfortunately, lake sediment is subject to remobilization and mixing due to a variety of sediment transport processes, such as mass wasting. There has been limited research on how base-level change influences mass wasting, in particular, slope failure. Some studies suggest slope failures are correlated with base-level fall and/or base-level rise, while others suggest they don’t correlate at all. To address this controversy, I conducted flume experiments at the Saint Anthony Falls Laboratory (SAFL) to observe slope failure in sediment mixtures containing four different walnut-shell/kaolinite ratios. Three base-level change rates were tested, producing 12 base-level change experiments. Another set of experiments was also designed to investigate what effect, if any, the addition of waves would have on mass flow. Video recordings were taken during each experiment and were analyzed to study the geometry of each profile before and after base-level change had occurred. Results suggest that there is consistent sediment transport when waves are present, aiding in the transportation of walnut-shell downslope. Without waves, transport is limited, and the clinoform is subject to compaction, or slump formation, depending on clay content. This difference depends heavily on a sediment’s composition, where hydraulic conductivity (K) plays an important role in water transmission through the clinoform. My experiments suggest that slope failures in the field would occur in lake sediment with higher clay content. Base-level change itself has no effect on the occurrence of failures, but slope failures should occur during base-level change if clay content is high. With only base-level change, we can expect to see compacted lake sediment with lower clay content (~15-33% clay). Slope failures (slumps) occur in lake sediment with higher clay content (~50%). With the presence of waves, however, wavebase plays an important role in sediment transport. Wave-base greatly influences sediment transport downslope, which is seen in my experimental work. This suggests that waves in the field also transport lake sediment downslope while washing away any finegrained particles (i.e. clay).
Subjects/Keywords: failure; lake; mass failure; sediment; slope; slump
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
LaGarde, M. (2018). The morphodynamic influence of base-level change and waves on lake sediment. (Masters Thesis). University of Minnesota. Retrieved from http://hdl.handle.net/11299/201726
Chicago Manual of Style (16th Edition):
LaGarde, Michelle. “The morphodynamic influence of base-level change and waves on lake sediment.” 2018. Masters Thesis, University of Minnesota. Accessed January 23, 2021.
http://hdl.handle.net/11299/201726.
MLA Handbook (7th Edition):
LaGarde, Michelle. “The morphodynamic influence of base-level change and waves on lake sediment.” 2018. Web. 23 Jan 2021.
Vancouver:
LaGarde M. The morphodynamic influence of base-level change and waves on lake sediment. [Internet] [Masters thesis]. University of Minnesota; 2018. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/11299/201726.
Council of Science Editors:
LaGarde M. The morphodynamic influence of base-level change and waves on lake sediment. [Masters Thesis]. University of Minnesota; 2018. Available from: http://hdl.handle.net/11299/201726

University of Texas – Austin
9.
-7997-3272.
Localization and failure of Aluminum 6061-T6 under biaxial loading.
Degree: PhD, Engineering Mechanics, 2019, University of Texas – Austin
URL: http://dx.doi.org/10.26153/tsw/2142
► The adoption of new materials for light-weighting purposes in the automotive industry has been hindered by these materials’ limited ductility and more-complicated constitutive models. Establishing…
(more)
▼ The adoption of new materials for light-weighting purposes in the automotive industry has been hindered by these materials’ limited ductility and more-complicated constitutive models. Establishing the onset of
failure through experiment is challenging, and numerical predictions depend strongly on the adopted material model. With this in mind, a series of experiments was developed with the goal of providing directly-measurable strains and stresses at
failure. Custom-designed Al 6061 T6 tubular specimens with a thin-walled test section are loaded in radial stress paths in the nominal axial-shear stress space. Stereo digital image correlation is used to monitor the specimen surface throughout the experiment. The stress and deformation within the test section are uniform until a load maximum is reached, beyond which deformation localizes into a circumferential band with width the order of the wall thickness. The series of experiments shows that the strain at
failure monotonically increases as the triaxiality decreases, a result that is contrary to previously-reported results for this alloy. The strains at
failure are also significantly larger than previously-reported values, with equivalent strains around 1.5 at low triaxialities. This experimental methodology provides a robust means of directly establishing
failure strains that can be employed as
failure criteria in numerical simulations. In support of a separate effort to numerically reproduce the responses and localization in these tension-torsion experiments, a series of combined tension and internal pressure experiments on the same tube stock was conducted. In these experiments, the tubes are loaded in radial paths in the nominal axial-hoop stress space. The data obtained proved sufficient for calibrating the non-quadratic, 18-parameter, anisotropic constitutive model of Barlat and coworkers. With the calibrated constitutive model, a large-deformation material stress-strain curve was inversely extracted from the post-necking response in a uniaxial tension test. The pressure-tension experiments were then studied numerically through a finite element (FE) model that incorporated the calibrated constitutive model and hardening response. The analysis shows that properly-calibrated plasticity with an accurate stress-strain curve and suitable FE mesh is capable of reproducing the measured responses as well as the localized deformations that developed prior to burst.
Advisors/Committee Members: Kyriakides, S. (advisor), Kovar, Desiderio (committee member), Liechti, Kenneth (committee member), Mear, Mark (committee member), Ravi-Chandar, Krishnaswamy (committee member).
Subjects/Keywords: Localization; Failure; Plasticity; Ductile failure; Plasticity; Anisotropy
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
-7997-3272. (2019). Localization and failure of Aluminum 6061-T6 under biaxial loading. (Doctoral Dissertation). University of Texas – Austin. Retrieved from http://dx.doi.org/10.26153/tsw/2142
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Chicago Manual of Style (16th Edition):
-7997-3272. “Localization and failure of Aluminum 6061-T6 under biaxial loading.” 2019. Doctoral Dissertation, University of Texas – Austin. Accessed January 23, 2021.
http://dx.doi.org/10.26153/tsw/2142.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
MLA Handbook (7th Edition):
-7997-3272. “Localization and failure of Aluminum 6061-T6 under biaxial loading.” 2019. Web. 23 Jan 2021.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Vancouver:
-7997-3272. Localization and failure of Aluminum 6061-T6 under biaxial loading. [Internet] [Doctoral dissertation]. University of Texas – Austin; 2019. [cited 2021 Jan 23].
Available from: http://dx.doi.org/10.26153/tsw/2142.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Council of Science Editors:
-7997-3272. Localization and failure of Aluminum 6061-T6 under biaxial loading. [Doctoral Dissertation]. University of Texas – Austin; 2019. Available from: http://dx.doi.org/10.26153/tsw/2142
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete

University of Oxford
10.
Rayner, Jennifer.
The effects of obesity and weight loss in heart failure : imaging the obesity paradox using magnetic resonance imaging and spectroscopy.
Degree: PhD, 2019, University of Oxford
URL: http://ora.ox.ac.uk/objects/uuid:a44bd194-5775-43c6-a1ad-abb8f2213323
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.804417
► Obesity and cardiovascular function are closely linked on a number of different levels, from the impact of the whole-body complications of obesity, to the geometric…
(more)
▼ Obesity and cardiovascular function are closely linked on a number of different levels, from the impact of the whole-body complications of obesity, to the geometric remodelling inflicted on the heart and vasculature by increased body weight, to the influence of the endocrine state of the body on intracellular signalling cascades, to the very efficiency of energy generation and transfer within the myocyte itself. Whilst obesity is one of the main contributing risks to the development of number of different cardiovascular diseases, it has a particularly strong relationship with the development of heart failure. However, there is a counterintuitive association with survival in established disease and increasing body mass index, known as the obesity paradox. This underlines the complex relationship between the two conditions, and poses the question as to whether there is a protective physiological mechanism at play within the obese myocardium. Magnetic resonance imaging is perfectly placed to interrogate this interplay in more detail, being the gold-standard technique for assessing a number of different parameters of cardiovascular structure and function, but also unveiling the potential for investigating cellular physiological parameters using non-invasive spectroscopic techniques. It is known that inflexibility in substrate selection has an impact on cardiovascular function and that this plays an important role in the development of diabetic cardiomyopathy, as well as potentially the obesity phenotype. In this thesis, I use the popular Very Low Calorie Diet in a healthy obese cohort, both to assess its efficacy in treating obesity-related cardiovascular disease, and also to demonstrate the impact of altering the availability of myocardial substrate on cardiovascular function. While after 8 weeks of dietary intervention, myocardial steatosis and diastolic dysfunction are reversed, there is an interesting early deterioration in function, associated with an increase in circulating fatty acids and deposition of ectopic lipid within the myocardium. This highlights the potential for dietary intervention as a treatment strategy in metabolic cardiac dysfunction, but also the need for caution in a population with pre-existing cardiovascular disease. While substrate selection is an important factor in determining the efficiency of energy generation, the rate of transfer of ATP from the mitochondrion to the myofibril is also a key step in regulating myocardial energy transduction. This step is catalysed by the creatine kinase enzyme, enabling PCr to act as a buffer maintaining rates of ATP delivery under fluctuating demand. The reaction rate of creatine kinase can be interrogated with sophisticated non-invasive MR spectroscopic techniques, and has been found to be reduced in heart failure. In obesity, however, there is typically preserved systolic function despite reduced PCr/ATP concentrations, which raises the question of whether creatine kinase kinetics compensate to maintain ATP delivery. I investigated this question in obese…
Subjects/Keywords: Obesity; Heart failure
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Rayner, J. (2019). The effects of obesity and weight loss in heart failure : imaging the obesity paradox using magnetic resonance imaging and spectroscopy. (Doctoral Dissertation). University of Oxford. Retrieved from http://ora.ox.ac.uk/objects/uuid:a44bd194-5775-43c6-a1ad-abb8f2213323 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.804417
Chicago Manual of Style (16th Edition):
Rayner, Jennifer. “The effects of obesity and weight loss in heart failure : imaging the obesity paradox using magnetic resonance imaging and spectroscopy.” 2019. Doctoral Dissertation, University of Oxford. Accessed January 23, 2021.
http://ora.ox.ac.uk/objects/uuid:a44bd194-5775-43c6-a1ad-abb8f2213323 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.804417.
MLA Handbook (7th Edition):
Rayner, Jennifer. “The effects of obesity and weight loss in heart failure : imaging the obesity paradox using magnetic resonance imaging and spectroscopy.” 2019. Web. 23 Jan 2021.
Vancouver:
Rayner J. The effects of obesity and weight loss in heart failure : imaging the obesity paradox using magnetic resonance imaging and spectroscopy. [Internet] [Doctoral dissertation]. University of Oxford; 2019. [cited 2021 Jan 23].
Available from: http://ora.ox.ac.uk/objects/uuid:a44bd194-5775-43c6-a1ad-abb8f2213323 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.804417.
Council of Science Editors:
Rayner J. The effects of obesity and weight loss in heart failure : imaging the obesity paradox using magnetic resonance imaging and spectroscopy. [Doctoral Dissertation]. University of Oxford; 2019. Available from: http://ora.ox.ac.uk/objects/uuid:a44bd194-5775-43c6-a1ad-abb8f2213323 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.804417

Addis Ababa University
11.
TIGIST, ANTENEH.
HYDRAULIC FAILURE OF MICRO EMBANKMENT DAMS AND REMEDIAL MEASURES CASE STUDY: ZANA MED, AMHARA REGION)
.
Degree: 2012, Addis Ababa University
URL: http://etd.aau.edu.et/dspace/handle/123456789/4097
► The main intention of this study is identifying the causes of hydraulic failure of Zana Micro- Embankment dam with emphasize on seepage. The selected area…
(more)
▼ The main intention of this study is identifying the causes of hydraulic
failure of Zana Micro-
Embankment dam with emphasize on seepage. The selected area is found in Amhara National
regional state, North Gonder zone, East Belesa woreda. The dam is located on Zana River,
tributary of the Tekeze River.
Even though the study area has been selected based on the available data as compared with the
other problem area, to attain the primary objective of the research the available data is so limited.
The work has delt with a unidirectional investigation. Seepage analysis and filter media design of
the dam which has been stated in the design document were thoroughly investigated.
Darcy’s law-phreatic line, flow Net and SEEP/W software model are used to analyze the quantity
of seepage through homogeneous and zoned dam, without the provision of filter material. The
flow net diagram is drawn with help of AutoCAD soft ware aided by free hand sketching for both
cases.
The expected quantity of seepage estimated with these different methods relatively resembles
each other. The maximum seepage through the dam as per the SEEP/W software model analysis
that includes foundation seepage is 7.06*10-3 cm3/sec. This value is compared with the quantity
of seepage estimated at the designed document that is 7.31*10-2cm3/sec. Therefore, the design
document has no problem of quantifying the expected quantity of seepage. However, the drainage
system is not properly designed at the design document. To this end, failurity of seepage at the d/s
face of the dam which are threatening the dam stability are expected to result from improper filter
media design. Even though, the dam has a problem data on construction history, this study
analyze with the help of field investigation, the cause of seepage failurity at side of spillway due
to poor construction quality.
To alleviate the problem grouting, impervious blanketing and d/s berming are the proposed
remedial measures for seepage and leakage failures.
Advisors/Committee Members: Dr. Bayou Chane (advisor).
Subjects/Keywords: HYDRAULIC FAILURE;
REMEDIAL
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
TIGIST, A. (2012). HYDRAULIC FAILURE OF MICRO EMBANKMENT DAMS AND REMEDIAL MEASURES CASE STUDY: ZANA MED, AMHARA REGION)
. (Thesis). Addis Ababa University. Retrieved from http://etd.aau.edu.et/dspace/handle/123456789/4097
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
TIGIST, ANTENEH. “HYDRAULIC FAILURE OF MICRO EMBANKMENT DAMS AND REMEDIAL MEASURES CASE STUDY: ZANA MED, AMHARA REGION)
.” 2012. Thesis, Addis Ababa University. Accessed January 23, 2021.
http://etd.aau.edu.et/dspace/handle/123456789/4097.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
TIGIST, ANTENEH. “HYDRAULIC FAILURE OF MICRO EMBANKMENT DAMS AND REMEDIAL MEASURES CASE STUDY: ZANA MED, AMHARA REGION)
.” 2012. Web. 23 Jan 2021.
Vancouver:
TIGIST A. HYDRAULIC FAILURE OF MICRO EMBANKMENT DAMS AND REMEDIAL MEASURES CASE STUDY: ZANA MED, AMHARA REGION)
. [Internet] [Thesis]. Addis Ababa University; 2012. [cited 2021 Jan 23].
Available from: http://etd.aau.edu.et/dspace/handle/123456789/4097.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
TIGIST A. HYDRAULIC FAILURE OF MICRO EMBANKMENT DAMS AND REMEDIAL MEASURES CASE STUDY: ZANA MED, AMHARA REGION)
. [Thesis]. Addis Ababa University; 2012. Available from: http://etd.aau.edu.et/dspace/handle/123456789/4097
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Wake Forest University
12.
Love, Nathan.
THE RELATIONSHIP BETWEEN SELF-REPORT AND PERFORMANCE-BASED MEASURES OF PHYSICAL FUNCTION FOLLOWING AN INTENSIVE CARE UNIT STAY.
Degree: 2016, Wake Forest University
URL: http://hdl.handle.net/10339/59265
► PURPOSE: The relationship between self-report and performance-based measures of physical function has not been addressed in ICU patients. The purpose of this study was to…
(more)
▼ PURPOSE: The relationship between self-report and performance-based measures of physical function has not been addressed in ICU patients. The purpose of this study was to examine this association in these patients. METHODS: 300 ICU patients were randomized into an exercise program (ExP) or standard of care (SoC). Self-report (SF-36 Physical Function Subscale (SF-36pfs), Functional Performance Inventory-Short Form (FPI-SF)) as well as performance-based (Short Physical Performance Battery (SPPB), skeletal muscle strength) measures were taken at hospital discharge, 2, 4, and 6 months post-enrollment. Partial correlations between self-report and performance-based measures of physical function in each group were calculated. Covariates included age, APACHE III score, and gender. Alpha was set at p < 0.05. RESULTS: At hospital discharge, a significant, but weak, correlation (r = 0.32) was found between the SF-36 and SPPB in the SoC group. At 2 months, weak to moderate correlations were found between self-report and performance measures in both groups. In the SoC group, the SF-36 was significantly correlated with the SPPB (r = 0.47) and muscular strength (r = 0.34); the FPI was significantly correlated with the SPPB (r = 0.64) and muscular strength (r = 0.52. In the ExP group, the SF-36 was significantly correlated with the SPPB (r = 0.61) and muscular strength (r = 0.42); the FPI was significantly correlated with the SPPB (r = 0.54) and with muscular strength (r = 0.28). A similar pattern was seen at 4 and 6 months in both groups. CONCLUSION: Self-report and performance-based measures of physical function appear to assess different constructs at hospital discharge. Following recovery from an ICU stay, these measures become complementary, but indicate different constructs are being assessed.
Subjects/Keywords: acute respiratory failure
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Love, N. (2016). THE RELATIONSHIP BETWEEN SELF-REPORT AND PERFORMANCE-BASED MEASURES OF PHYSICAL FUNCTION FOLLOWING AN INTENSIVE CARE UNIT STAY. (Thesis). Wake Forest University. Retrieved from http://hdl.handle.net/10339/59265
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Love, Nathan. “THE RELATIONSHIP BETWEEN SELF-REPORT AND PERFORMANCE-BASED MEASURES OF PHYSICAL FUNCTION FOLLOWING AN INTENSIVE CARE UNIT STAY.” 2016. Thesis, Wake Forest University. Accessed January 23, 2021.
http://hdl.handle.net/10339/59265.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Love, Nathan. “THE RELATIONSHIP BETWEEN SELF-REPORT AND PERFORMANCE-BASED MEASURES OF PHYSICAL FUNCTION FOLLOWING AN INTENSIVE CARE UNIT STAY.” 2016. Web. 23 Jan 2021.
Vancouver:
Love N. THE RELATIONSHIP BETWEEN SELF-REPORT AND PERFORMANCE-BASED MEASURES OF PHYSICAL FUNCTION FOLLOWING AN INTENSIVE CARE UNIT STAY. [Internet] [Thesis]. Wake Forest University; 2016. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/10339/59265.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Love N. THE RELATIONSHIP BETWEEN SELF-REPORT AND PERFORMANCE-BASED MEASURES OF PHYSICAL FUNCTION FOLLOWING AN INTENSIVE CARE UNIT STAY. [Thesis]. Wake Forest University; 2016. Available from: http://hdl.handle.net/10339/59265
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Australian National University
13.
Liang, Jiaai.
Investigation of Failure Behaviour of a Glass-Fibre Reinforced Thermoplastic Composite
.
Degree: 2017, Australian National University
URL: http://hdl.handle.net/1885/143658
► This work focuses on the fibre dominated failure of the woven thermoplastic fibre-reinforced composite. The novel experimental methodology induced failures in different deformation modes for…
(more)
▼ This work focuses on the fibre dominated failure of the woven
thermoplastic fibre-reinforced composite. The novel experimental
methodology induced failures in different deformation modes for
the Glass Fibre Reinforced Polypropylene (GFRP) composite
studied. Hence the path dependency effect on the failure of this
material system can be studied experimentally through the
three-dimensional (3D) Digital Image Correlation (DIC) system. A
novel failure metric based on the strains experienced by the
fibre bundles is developed. From the experimental results, this
failure metric is found to be able to eliminate path dependency
effect and is independent of fibre orientations. In Finite
Element Analysis (FEA), this failure metric is incorporated with
the simulations as a virtual tool to predict failures of the GFRP
material.
From the experimental results, failure envelopes with the failure
metric based on the principal strain and fibre strain are
developed respectively. Both failure envelopes are implemented in
the FEA simulation. The simulations incorporated with the failure
metric in principal strain cannot accurately predict failure for
the GFRP material system. The simulations incorporated with the
failure metric in fibre strain, on the contrary, are found to be
able to provide predictions that have a better agreement with the
experimental results.
Subjects/Keywords: Thermoplastic;
Composite;
Failure
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Liang, J. (2017). Investigation of Failure Behaviour of a Glass-Fibre Reinforced Thermoplastic Composite
. (Thesis). Australian National University. Retrieved from http://hdl.handle.net/1885/143658
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Liang, Jiaai. “Investigation of Failure Behaviour of a Glass-Fibre Reinforced Thermoplastic Composite
.” 2017. Thesis, Australian National University. Accessed January 23, 2021.
http://hdl.handle.net/1885/143658.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Liang, Jiaai. “Investigation of Failure Behaviour of a Glass-Fibre Reinforced Thermoplastic Composite
.” 2017. Web. 23 Jan 2021.
Vancouver:
Liang J. Investigation of Failure Behaviour of a Glass-Fibre Reinforced Thermoplastic Composite
. [Internet] [Thesis]. Australian National University; 2017. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/1885/143658.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Liang J. Investigation of Failure Behaviour of a Glass-Fibre Reinforced Thermoplastic Composite
. [Thesis]. Australian National University; 2017. Available from: http://hdl.handle.net/1885/143658
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Exeter
14.
Casely, William Robert.
An analysis of intelligent failure within corporate entrepreneurship.
Degree: PhD, 2016, University of Exeter
URL: http://hdl.handle.net/10871/27620
► Intelligent failure occurs when an entrepreneurial initiative falls short of its anticipated performance. It provides valuable new knowledge to the organisation and is recognised as…
(more)
▼ Intelligent failure occurs when an entrepreneurial initiative falls short of its anticipated performance. It provides valuable new knowledge to the organisation and is recognised as an important factor in long-term corporate entrepreneurial success. This thesis is located within the domain of corporate entrepreneurship and entrepreneurial failure, and explores the various processes of intelligent failure. The specific aim of this thesis is to learn how organisations manage intelligent failure. Research takes an inductive approach with the predominant use of a qualitative methodology and, as part of a multiple case study strategy, research is carried out in six organisations operating in differing sectors within the UK. Findings indicate that the organisations often fail to manage intelligent failure. There is little evidence of a strategic approach to learning from failure and, where learning occurs, it is predominantly unstructured. This is significant because literature consistently argues that a structured process is required to manage learning from failure successfully. This research recognises that structured processes may be more effective than unstructured processes when looked at in isolation. However, this thesis argues that unstructured mechanisms do have inherent value. Therefore, when organisations develop failure management processes, a dual path may be considered, which might extract value from both systems as is contextually appropriate. This may enable organisations to maximise their ability to learn from failure. This thesis adds to existing management theory in the corporate entrepreneurship domain. In specifically focusing on the structured and unstructured forms within the process of intelligent failure, this thesis addresses a gap in current literature. It also adds to existing literature that centres on the practical management of the learning from failure process.
Subjects/Keywords: 658.4; Intelligent failure; Learning from failure; Managing intelligent failure; Entrepreneurial failure; Entrepreneurial environment
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Casely, W. R. (2016). An analysis of intelligent failure within corporate entrepreneurship. (Doctoral Dissertation). University of Exeter. Retrieved from http://hdl.handle.net/10871/27620
Chicago Manual of Style (16th Edition):
Casely, William Robert. “An analysis of intelligent failure within corporate entrepreneurship.” 2016. Doctoral Dissertation, University of Exeter. Accessed January 23, 2021.
http://hdl.handle.net/10871/27620.
MLA Handbook (7th Edition):
Casely, William Robert. “An analysis of intelligent failure within corporate entrepreneurship.” 2016. Web. 23 Jan 2021.
Vancouver:
Casely WR. An analysis of intelligent failure within corporate entrepreneurship. [Internet] [Doctoral dissertation]. University of Exeter; 2016. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/10871/27620.
Council of Science Editors:
Casely WR. An analysis of intelligent failure within corporate entrepreneurship. [Doctoral Dissertation]. University of Exeter; 2016. Available from: http://hdl.handle.net/10871/27620

University of Waikato
15.
Singh, Smita.
Experiencing and Learning from Entrepreneurial Failure
.
Degree: 2011, University of Waikato
URL: http://hdl.handle.net/10289/5965
► Entrepreneurship literature has long focused on stories of entrepreneurial success. However, in recent years consensus has begun to build around the importance of also studying…
(more)
▼ Entrepreneurship literature has long focused on stories of entrepreneurial success. However, in recent years consensus has begun to build around the importance of also studying
failure in order to develop a more holistic understanding of entrepreneurship. It has been argued that
failure can have an impact on entrepreneurial decision-making in subsequent ventures and can be a difficult experience for an entrepreneur to go through. In spite of such speculations and acknowledgements,
failure remains a relatively underresearched area, except perhaps from the primary perspective of the reasons behind
failure. While this is an important area of investigation − as understanding reasons behind
failure can improve the probability of success in subsequent entrepreneurial endeavours – it is equally important to understand the experience of
failure. The primary aim of this thesis is to understand
failure from the perspective of entrepreneurs who have experienced it. Its second aim is to build a theoretical framework of
failure based on those experiences.
The overarching research question for this study is: “How do entrepreneurs experience venture
failure and learn from this experience?” The three supporting subquestions are: “What do entrepreneurs experience when their venture fails?”, “How do entrepreneurs stay resilient when the venture fails?”, and “What do the entrepreneurs learn from experiencing venture
failure?” Using the philosophical position of interpretive, phenomenological symbolic interactionism and narrative as a strategy of inquiry, stories of
failure as told by 21 entrepreneurs during in-depth interviews are analysed. Using the metaphor of fabric tear and repair, theoretical constructs developed from the findings are integrated into a framework and discussed in the light of relevant literature. The framework highlights that
failure leads to considerable challenges for the entrepreneurs and triggers grief. After grief, however, comes resilience. In this journey, resilience came from acceptance and hope, states that shifted the entrepreneurs’ perspective on venture
failure from one which saw it as a negative, end-all event to one that framed it as a challenging, survivable event. This resilience fuelled their efforts to adapt to their changed reality. Grief faded as entrepreneurs dealt with the challenges. From this experience, the entrepreneurs learnt business lessons and transformed in such a way as to become more spiritually inclined.
The study extends the understanding of the phenomenon of
failure in entrepreneurship by presenting an empirical evidence-based framework that incorporates
failure-related challenges, entrepreneurs’ adaptation to these challenges, and the lessons learnt from this experience. Second, this study illustrates the importance of hope and acceptance in building entrepreneurial resilience, and how entrepreneurs’ social environment and sometimes spiritual beliefs play an important role in nurturing hope and an acceptance of adapting to the challenges. Policy makers, educators,…
Advisors/Committee Members: Pavlovich, Kathryn (advisor), Corner, Patricia (advisor).
Subjects/Keywords: venture failure;
grief
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Singh, S. (2011). Experiencing and Learning from Entrepreneurial Failure
. (Doctoral Dissertation). University of Waikato. Retrieved from http://hdl.handle.net/10289/5965
Chicago Manual of Style (16th Edition):
Singh, Smita. “Experiencing and Learning from Entrepreneurial Failure
.” 2011. Doctoral Dissertation, University of Waikato. Accessed January 23, 2021.
http://hdl.handle.net/10289/5965.
MLA Handbook (7th Edition):
Singh, Smita. “Experiencing and Learning from Entrepreneurial Failure
.” 2011. Web. 23 Jan 2021.
Vancouver:
Singh S. Experiencing and Learning from Entrepreneurial Failure
. [Internet] [Doctoral dissertation]. University of Waikato; 2011. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/10289/5965.
Council of Science Editors:
Singh S. Experiencing and Learning from Entrepreneurial Failure
. [Doctoral Dissertation]. University of Waikato; 2011. Available from: http://hdl.handle.net/10289/5965

University of Arizona
16.
Givens, Genevieve.
Con Confianza: Improving Heart Failure Knowledge for Spanish Speaking Patients at a Transitional Care Clinic in Southwest Arizona
.
Degree: 2019, University of Arizona
URL: http://hdl.handle.net/10150/636558
► Background: Heart failure is defined by the American Heart Association (AHA) as a chronic, progressive, and costly disease in which the heart is unable to…
(more)
▼ Background: Heart
failure is defined by the American Heart Association (AHA) as a chronic, progressive, and costly disease in which the heart is unable to meet the demands of the body, affecting millions of people worldwide (2019). A need assessment completed at Yuma Regional Medical Center’s Transitional Care Services clinic in Southwest Arizona identified Spanish speaking Latinos overwhelmingly lacked heart
failure knowledge despite standard patient education and the use of comprehensive educational materials. In order to address health concerns in this patient population, a quality improvement project aimed at improving heart
failure knowledge in Spanish speaking patients was conducted. Methods: This quality improvement project used quantitative surveys to evaluate the effectiveness of integrating American Heart Association’s (AHA, 2019) Spanish version self-check plan for heart
failure management tool into routine patient education at TCS for Spanish speaking patients. Demographic, heart
failure knowledge and patient self-management confidence levels were obtained prior to the visit. After the visit, participants were given two surveys to reassess their self- management confidence levels and determine their satisfaction with the educational tool. Participants were also given the opportunity to comment upon their experience provided insight of the usefulness of the educational tool, the project, and the TCS clinic. Results: Thirty-four patients from the TCS participated in this project. The majority of participants were male, older than 65 years, and had a less than or equal to a 3rd grade education. Confidence levels dramatically improved between baseline (66.4%) and post-intervention (90.6%). This demonstrates the effectiveness of this educational intervention which integrating an easy to follow illustrated heart
failure zone tool. Conclusion: The local need to address Latino health issues is widely apparent and this quality improvement project revealed that the development and implementation of language and literacy specific patient education materials significantly impacted participant confidence levels in managing HF. Recommendations: Findings from this project highly encourage further assessment of baseline health and reading literacy and the use of language and low literacy focused patient education materials.
Advisors/Committee Members: Pacheco, Christy (advisor), Daly, Patricia (committeemember), Flamm, Kristie (committeemember).
Subjects/Keywords: Heart Failure;
Latinos
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Givens, G. (2019). Con Confianza: Improving Heart Failure Knowledge for Spanish Speaking Patients at a Transitional Care Clinic in Southwest Arizona
. (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/636558
Chicago Manual of Style (16th Edition):
Givens, Genevieve. “Con Confianza: Improving Heart Failure Knowledge for Spanish Speaking Patients at a Transitional Care Clinic in Southwest Arizona
.” 2019. Doctoral Dissertation, University of Arizona. Accessed January 23, 2021.
http://hdl.handle.net/10150/636558.
MLA Handbook (7th Edition):
Givens, Genevieve. “Con Confianza: Improving Heart Failure Knowledge for Spanish Speaking Patients at a Transitional Care Clinic in Southwest Arizona
.” 2019. Web. 23 Jan 2021.
Vancouver:
Givens G. Con Confianza: Improving Heart Failure Knowledge for Spanish Speaking Patients at a Transitional Care Clinic in Southwest Arizona
. [Internet] [Doctoral dissertation]. University of Arizona; 2019. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/10150/636558.
Council of Science Editors:
Givens G. Con Confianza: Improving Heart Failure Knowledge for Spanish Speaking Patients at a Transitional Care Clinic in Southwest Arizona
. [Doctoral Dissertation]. University of Arizona; 2019. Available from: http://hdl.handle.net/10150/636558

Rutgers University
17.
Hegyi, Gina N., 1991-.
Arterial hemodynamics and its interaction with the left ventricle in heart failure.
Degree: MS, Biomedical Engineering, 2015, Rutgers University
URL: https://rucore.libraries.rutgers.edu/rutgers-lib/48508/
► Monitoring heart-arterial system (LV-AS) interactions of cardiovascular patients is important in achieving successful diagnosis and treatment. This is particularly true in the cases of hypertension…
(more)
▼ Monitoring heart-arterial system (LV-AS) interactions of cardiovascular patients is important in achieving successful diagnosis and treatment. This is particularly true in the cases of hypertension and heart
failure. However, there has been limited quantitative hemodynamic analysis aimed at improving the outcome for the 70-million hypertensive patients and millions of heart
failure patients. This thesis develops a model-based strategy to provide a comprehensive evaluation of the state of the vascular system and its coupling to the heart, and ultimately aims to distinguish patient groups of heart
failure with preserved or reduced ejection fraction (HFpEF and HFrEF). The first aspect of this study is analysis of arterial hemodynamics from animal experimental data collected during normotensive, vasodilation, and induced hypertension conditions. Total arterial compliance (C), peripheral resistance (Rs), and aortic characteristic impedance (Z0) based on the 3-element Windkessel model were obtained, together with frequency-domain impedance, wave reflection information, and parameters for assessing global cardiac function. Subsequently, clinical human data were collected and analyzed, focusing on the LV-AS interactions. We identified critical parameters in LV-AS interaction, i.e. effective arterial system elastance, Ea, LV systolic elastance, Emax, LV-AS coupling index, k (=Ea/Emax), and C. Results characterized hypertension by a significantly reduced C and increased Rs, confirmed by increased vascular impedance and wave reflections. Unloading the heart reversed these observations via vasodilator treatment. For human studies, we found C to be more effective than Ea in distinguishing groups of HFpEF and HFrEF patients. It was found that HFpEF patients tended to have a relatively independent coupling index, k, with respect to arterial parameter changes. The findings in this work can be incorporated into larger scale clinical studies that implement the use of pulse waveform analysis and the identified critical LV-AS interaction parameters to improve patient treatment and outcome.
Advisors/Committee Members: Li, John K-J. (chair).
Subjects/Keywords: Heart failure; Hemodynamics
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Hegyi, Gina N., 1. (2015). Arterial hemodynamics and its interaction with the left ventricle in heart failure. (Masters Thesis). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/48508/
Chicago Manual of Style (16th Edition):
Hegyi, Gina N., 1991-. “Arterial hemodynamics and its interaction with the left ventricle in heart failure.” 2015. Masters Thesis, Rutgers University. Accessed January 23, 2021.
https://rucore.libraries.rutgers.edu/rutgers-lib/48508/.
MLA Handbook (7th Edition):
Hegyi, Gina N., 1991-. “Arterial hemodynamics and its interaction with the left ventricle in heart failure.” 2015. Web. 23 Jan 2021.
Vancouver:
Hegyi, Gina N. 1. Arterial hemodynamics and its interaction with the left ventricle in heart failure. [Internet] [Masters thesis]. Rutgers University; 2015. [cited 2021 Jan 23].
Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/48508/.
Council of Science Editors:
Hegyi, Gina N. 1. Arterial hemodynamics and its interaction with the left ventricle in heart failure. [Masters Thesis]. Rutgers University; 2015. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/48508/

Georgia State University
18.
Swiniarski, Jessica.
Factors Contributing to Condom Failure.
Degree: MPH, Public Health, 2019, Georgia State University
URL: https://scholarworks.gsu.edu/iph_theses/651
► Introduction There are many personal and behavioral factors that can decrease the effectiveness of condoms, even when one is used every time. Clinical condom…
(more)
▼ Introduction There are many personal and behavioral factors that can decrease the effectiveness of condoms, even when one is used every time. Clinical condom
failure (the condom breaking, tearing, or completely slipping off the penis) contributes to less than perfect effectiveness rates and can be at least partially attributed to these personal and behavioral factors. Although specific use and storage behaviors can be reasons for a condom to break or slip, there are often other factors at play. Negative perceptions of condoms, self-efficacy when using condoms, type of sex act, and history of STI’s can all impact clinical
failure rates.
Objective The purpose of this study was to assess four major factors: negative perceptions of condoms, self-efficacy, history of STI’s, and type of sex act, and their relationship to condom breakage and slippage in a sample of 381 condom users in Atlanta, GA.
Methods Data were drawn from the baseline survey of the C-PLEASURE Study. Bivariate analyses were conducted to determine the relationship between each independent variable and the two outcome variables: experiencing condom breakage in the last 6 months and experiencing condom slippage in the last 6 months. Then two logistic regression models, one for experience of any condom breaks in the last six months and one for experience of any condom slips in the last six months, were used to further determine these relationships.
Results The only significant relationship that was found was between negative perceptions of condoms and condom slips (AOR=1.08 95% CI= [1.02, 1.14], p=0.01). History of STI’s, type of sex act, lubricant use, lubricant type, consistent condom use, and self-efficacy did not return any significant relationships with experience of condom breaks or slips in the last 6 months, although self-efficacy did approach a significant relationship with condom slips (p=.07).
Conclusions Since negative perceptions are correlated with condom
failure, attitudes and perceptions of condoms need to be addressed for greater efficacy. Further studies on self-efficacy and condom
failure should be pursued to determine how strong the protective qualities of self-efficacy can be when it comes to effective use of condoms and prevention of condom
failure.
Advisors/Committee Members: Dr. Laura Salazar, Dr. Aaron Siegler.
Subjects/Keywords: condoms; failure; STI
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Swiniarski, J. (2019). Factors Contributing to Condom Failure. (Thesis). Georgia State University. Retrieved from https://scholarworks.gsu.edu/iph_theses/651
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Swiniarski, Jessica. “Factors Contributing to Condom Failure.” 2019. Thesis, Georgia State University. Accessed January 23, 2021.
https://scholarworks.gsu.edu/iph_theses/651.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Swiniarski, Jessica. “Factors Contributing to Condom Failure.” 2019. Web. 23 Jan 2021.
Vancouver:
Swiniarski J. Factors Contributing to Condom Failure. [Internet] [Thesis]. Georgia State University; 2019. [cited 2021 Jan 23].
Available from: https://scholarworks.gsu.edu/iph_theses/651.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Swiniarski J. Factors Contributing to Condom Failure. [Thesis]. Georgia State University; 2019. Available from: https://scholarworks.gsu.edu/iph_theses/651
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Aberdeen
19.
Singh, Satnam.
Role of metabolic modulator perhexiline in heart failure with preserved ejection fraction syndrome.
Degree: PhD, 2019, University of Aberdeen
URL: https://eu03.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12153080010005941
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.816214
► Despite major advances, the pathophysiology of the syndrome of heart failure with preserved ejection fraction (HFpEF) is not completely understood but appears to be multifactorial.…
(more)
▼ Despite major advances, the pathophysiology of the syndrome of heart failure with preserved ejection fraction (HFpEF) is not completely understood but appears to be multifactorial. These patients often exhibit moderate to severe exercise limitation with considerable morbidity and mortality. Moreover, no effective treatment has been found to manage these patients despite several randomised clinical trials. Previous work from our group has demonstrated a potential role of cardiac energetic impairment in the pathophysiology of HFpEF. Furthermore in a study of patients with hypertrophic cardiomyopathy, the metabolic modulator Perhexiline was shown to improve cardiac energetic impairment and to increase exercise capacity. Therefore in this thesis I assessed the effects of Perhexiline on cardiac energetics, symptom status and exercise capacity in patients with HFpEF in a parallel group randomised placebo controlled trial. Perhexiline had no significant effect on these end points.
Subjects/Keywords: Perhexiline; Heart failure
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Singh, S. (2019). Role of metabolic modulator perhexiline in heart failure with preserved ejection fraction syndrome. (Doctoral Dissertation). University of Aberdeen. Retrieved from https://eu03.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12153080010005941 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.816214
Chicago Manual of Style (16th Edition):
Singh, Satnam. “Role of metabolic modulator perhexiline in heart failure with preserved ejection fraction syndrome.” 2019. Doctoral Dissertation, University of Aberdeen. Accessed January 23, 2021.
https://eu03.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12153080010005941 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.816214.
MLA Handbook (7th Edition):
Singh, Satnam. “Role of metabolic modulator perhexiline in heart failure with preserved ejection fraction syndrome.” 2019. Web. 23 Jan 2021.
Vancouver:
Singh S. Role of metabolic modulator perhexiline in heart failure with preserved ejection fraction syndrome. [Internet] [Doctoral dissertation]. University of Aberdeen; 2019. [cited 2021 Jan 23].
Available from: https://eu03.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12153080010005941 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.816214.
Council of Science Editors:
Singh S. Role of metabolic modulator perhexiline in heart failure with preserved ejection fraction syndrome. [Doctoral Dissertation]. University of Aberdeen; 2019. Available from: https://eu03.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12153080010005941 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.816214

Addis Ababa University
20.
Yosef, Bekele.
ailure analysis of signaling Failure analysis of signalingFailure analysis of signaling Failure analysis of signaling system of Addis Ababa system of Addis Ababasystem of Addis Ababa system of Addis Ababa – Light Rail Transit Light Rail TransitLight Rail Transit Light Rail Transit
.
Degree: 2015, Addis Ababa University
URL: http://etd.aau.edu.et/dspace/handle/123456789/7455
► Railway signaling system is one of the most important parts of the many which make up the railway system. It is the vital control system…
(more)
▼ Railway signaling system is one of the most important parts of the many which make up the
railway system. It is the vital control system which demands the use of reliable and fault tolerant
system as it directly related to the safe movement of passenger trains. Ensuring safety in railway
signaling systems is considered as significant as a guarantee of the safe and efficient operation of
the whole railway. In fact, one of the most important objectives of a safety analysis of the
signaling system is to maintain a high degree of safety.
Therefore, to avoid these problems and provide an optimized signaling, a signaling system
design should incorporate additional safety analysis. One of the safety analysis methods from
design stage is
failure analysis which is used to study the whole dynamic system, point out
potential
failure modes,
failure propagation scheme and used to predict about the system.
To this end, this thesis presents the
failure analysis of Addis Ababa-Light Rail Transit signaling
system by employing model-based
failure analysis methods and system fault tree, causes and
effects, major failures are investigated.
Failure propagation models for the subsystems of AA-LRT signaling system are modeled on
Matlab-Simulink, where signaling equipments in a main station are represented. Functional
interactions between those equipments are also represented.
Hierarchically Performed Hazard Origin and Propagation Studies (HiP-HOPS) is used from the
most common model-based safety analysis tools to define each signaling system equipment local
failure data and to analyze
failure models which are done on Simulink.
Fault trees are generated as a result for selected hazards in simulations showing the possible
causes of failures.
Advisors/Committee Members: Mr. Abi Abate (advisor).
Subjects/Keywords: Failure modes;
Failure propagation;
Model based failure analysis;
HiP-HOPS
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Yosef, B. (2015). ailure analysis of signaling Failure analysis of signalingFailure analysis of signaling Failure analysis of signaling system of Addis Ababa system of Addis Ababasystem of Addis Ababa system of Addis Ababa – Light Rail Transit Light Rail TransitLight Rail Transit Light Rail Transit
. (Thesis). Addis Ababa University. Retrieved from http://etd.aau.edu.et/dspace/handle/123456789/7455
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Yosef, Bekele. “ailure analysis of signaling Failure analysis of signalingFailure analysis of signaling Failure analysis of signaling system of Addis Ababa system of Addis Ababasystem of Addis Ababa system of Addis Ababa – Light Rail Transit Light Rail TransitLight Rail Transit Light Rail Transit
.” 2015. Thesis, Addis Ababa University. Accessed January 23, 2021.
http://etd.aau.edu.et/dspace/handle/123456789/7455.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Yosef, Bekele. “ailure analysis of signaling Failure analysis of signalingFailure analysis of signaling Failure analysis of signaling system of Addis Ababa system of Addis Ababasystem of Addis Ababa system of Addis Ababa – Light Rail Transit Light Rail TransitLight Rail Transit Light Rail Transit
.” 2015. Web. 23 Jan 2021.
Vancouver:
Yosef B. ailure analysis of signaling Failure analysis of signalingFailure analysis of signaling Failure analysis of signaling system of Addis Ababa system of Addis Ababasystem of Addis Ababa system of Addis Ababa – Light Rail Transit Light Rail TransitLight Rail Transit Light Rail Transit
. [Internet] [Thesis]. Addis Ababa University; 2015. [cited 2021 Jan 23].
Available from: http://etd.aau.edu.et/dspace/handle/123456789/7455.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Yosef B. ailure analysis of signaling Failure analysis of signalingFailure analysis of signaling Failure analysis of signaling system of Addis Ababa system of Addis Ababasystem of Addis Ababa system of Addis Ababa – Light Rail Transit Light Rail TransitLight Rail Transit Light Rail Transit
. [Thesis]. Addis Ababa University; 2015. Available from: http://etd.aau.edu.et/dspace/handle/123456789/7455
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Arizona
21.
Young, Janay R.
Defining Clinical Events for Heart Failure Patients
.
Degree: 2017, University of Arizona
URL: http://hdl.handle.net/10150/624519
► Heart failure (HF) is a serious, life limiting chronic illness and is the most common cause of <30-day hospital readmission, which is costly both in…
(more)
▼ Heart
failure (HF) is a serious, life limiting chronic illness and is the most common cause of <30-day hospital readmission, which is costly both in its profound negative impact on patient mortality and quality of life, and in economics. Limited access to care in rural communities increases the prevalence of hospitalizations for heart disease in rural areas. The aims of this project using data mined from Arizona Health Sciences Center Clinical Research Data Warehouse, are to define clinical events (fever, pain, changes in respiratory status, change in level of consciousness, changes in output, bleeding, and suicide ideation) for patients with heart
failure, and determine what assessment values are for chronically ill patients and compare to "normal" assessment values for non-chronically ill patients. A literature review was completed to determine how to define clinical events for chronically ill patients with HF, and how decision making is used at home to manage chronic illness. Assessment value data was mined from the clinical research data warehouse and compared to “normal” assessment values, with identification of associations between clinical events and action taken in the hospital. The project results support that there are differences in "normal" assessment values for fever, pain, and change in respiratory status between chronically ill patients with HF, and non-chronically ill patients; there was insufficient data to define bleeding, change in output, or suicide ideation. Impacts to care include earlier recognition of worsening HF symptoms that could result in an earlier call or visit to primary care provider forestalling the need for emergent care and hospital readmission. Application of the mined clinical may inform development of evidenced-based algorithm to guide decision-making at home, and it may also provide the foundation for the development of a tool for patient use to prevent <30-day hospital readmission.
Advisors/Committee Members: Carrington, Jane M (advisor), Carrington, Jane M. (committeemember), Love, Rene (committeemember), Pacheco, Christy L. (committeemember).
Subjects/Keywords: Decreasing Hospital Readmission;
Heart Failure Decision-Making;
Heart Failure Clinical Events;
Heart Failure Self-Management
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Young, J. R. (2017). Defining Clinical Events for Heart Failure Patients
. (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/624519
Chicago Manual of Style (16th Edition):
Young, Janay R. “Defining Clinical Events for Heart Failure Patients
.” 2017. Doctoral Dissertation, University of Arizona. Accessed January 23, 2021.
http://hdl.handle.net/10150/624519.
MLA Handbook (7th Edition):
Young, Janay R. “Defining Clinical Events for Heart Failure Patients
.” 2017. Web. 23 Jan 2021.
Vancouver:
Young JR. Defining Clinical Events for Heart Failure Patients
. [Internet] [Doctoral dissertation]. University of Arizona; 2017. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/10150/624519.
Council of Science Editors:
Young JR. Defining Clinical Events for Heart Failure Patients
. [Doctoral Dissertation]. University of Arizona; 2017. Available from: http://hdl.handle.net/10150/624519

Robert Gordon University
22.
Makropoulos, Alexios.
Firm failure processes and determinants of failure in EU countries and UK regions : a quantitative analysis of SMEs.
Degree: PhD, 2019, Robert Gordon University
URL: https://rgu-repository.worktribe.com/output/841432
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.800379
► This thesis is motivated by the fact that small and medium sized enterprises (SMEs) are of vital importance to most European countries collectively, and to…
(more)
▼ This thesis is motivated by the fact that small and medium sized enterprises (SMEs) are of vital importance to most European countries collectively, and to each country individually. For these reasons, understanding SME failure is an integral part of decision and policy making. Firm failure can be regarded as a multi-year process that develops over time. Yet there has been limited work in the area of quantitatively identifying and analysing SME failure processes. In particular, despite evidence from the qualitative firm failure process literature on the importance that non-financial, firm-specific characteristics have on firm failure processes, the quantitative firm failure process literature has largely ignored this aspect. Likewise, the determinants of firms' transition to failure within potential alternative firm failure processes and the importance of geographical location are often overlooked in the firm failure process literature, despite evidence in the wider firm failure literature for the contrary. For these reasons, the current evidence in the quantitative firm failure process literature is quite isolated from wider firm failure studies. This thesis aims to investigate alternative SME failure processes, the determinants of firms' transition towards failure and the importance of firms' geographical location by bringing evidence from other parts of the firm failure literature in the quantitative study of firm failure processes. The sample analysed consists of SMEs in eight EU countries, covering the period from 2004-2013. In addition to analysing the whole sample, the failure processes and failure determinants of UK failed SMEs are also investigated. The dataset of this study covers firm-specific characteristics - such as financial ratios and directors' characteristics - and information about the macroeconomic and business environment. In addition, the impact of geographical location is considered. The key results of the analysis identify the existence of four alternative firm failure processes (new firms with inexperienced boards, high growth firms, old firms, firms without board diversity) which apply across EU countries and UK regions. A number of other characteristics are also present in the alternative firm failure processes: directors characteristics are of primary importance for firm failure processes as well as firms' transition to failure. So are the age of the firm, the legal tradition of the country, the levels of business growth and the intensity of competition due to new business entrants in an area and the geographical location of firms. There are a number of contributions that this thesis makes to the quantitative firm failure process literature. First, given that the different failure processes were found to have differing determinants, the results show the importance of looking at individual firm failure processes rather than simply analysing all failed firms together. Second, this thesis is the first to quantitatively analyse the impact of directors' characteristics in the identification of…
Subjects/Keywords: Small and medium enterprises; Firm failure; Business failure; Enterprise failure; European Union; United Kingdom
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Makropoulos, A. (2019). Firm failure processes and determinants of failure in EU countries and UK regions : a quantitative analysis of SMEs. (Doctoral Dissertation). Robert Gordon University. Retrieved from https://rgu-repository.worktribe.com/output/841432 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.800379
Chicago Manual of Style (16th Edition):
Makropoulos, Alexios. “Firm failure processes and determinants of failure in EU countries and UK regions : a quantitative analysis of SMEs.” 2019. Doctoral Dissertation, Robert Gordon University. Accessed January 23, 2021.
https://rgu-repository.worktribe.com/output/841432 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.800379.
MLA Handbook (7th Edition):
Makropoulos, Alexios. “Firm failure processes and determinants of failure in EU countries and UK regions : a quantitative analysis of SMEs.” 2019. Web. 23 Jan 2021.
Vancouver:
Makropoulos A. Firm failure processes and determinants of failure in EU countries and UK regions : a quantitative analysis of SMEs. [Internet] [Doctoral dissertation]. Robert Gordon University; 2019. [cited 2021 Jan 23].
Available from: https://rgu-repository.worktribe.com/output/841432 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.800379.
Council of Science Editors:
Makropoulos A. Firm failure processes and determinants of failure in EU countries and UK regions : a quantitative analysis of SMEs. [Doctoral Dissertation]. Robert Gordon University; 2019. Available from: https://rgu-repository.worktribe.com/output/841432 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.800379

Universidade de Lisboa
23.
Henriques, Taigo Almeida.
Monitorização aplicacional - Sputnik, Checklist e Gateway Asterisk.
Degree: 2012, Universidade de Lisboa
URL: http://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/13864
► All information systems are prone to failures, whether they’re human, infrastructural or applicational, therefore requiring constant monitoring in order to prevent service unavailability affecting business.…
(more)
▼ All information systems are prone to failures, whether they’re human, infrastructural or applicational, therefore requiring constant monitoring in order to prevent service unavailability affecting business.
Sputnik is a platform for graphical and intuitive representation of infrastructural and applicational monitoring, allowing to represent circuits, tables, graphs or for example checking the availability of a server or the accumulation of records in a table. This platform allows real-time problem detection/visualization and supports it’s resolution/escalation
in a efficient way.
The Checklist is a centralized platform where knowledge and information are organized/ structured in CI’s (Configuration Items) and relationships between them. Intended as a framework for searching any type of relevant information, including relationships between the existing CIs.
Asterisk Gateway is a pilot platform (proof-of-concept), designed to trigger automatic
phone calls replacing the need for human action, thus speeding the process of scaling. In the context of this PEI, calls are triggered when a CI falis, alerting the respective support team.
In this PEI I intended not only, to improve/develop alarmistic platforms over the PTSI systems but also to improve my technical knowledge, management and effective input on the process of monitoring and alarms, minimizing human action and helping them when necessary.
Advisors/Committee Members: Coelho, João Sarmento, Coelho, Helder.
Subjects/Keywords: system; alarm; failure; CI; monitoting
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Henriques, T. A. (2012). Monitorização aplicacional - Sputnik, Checklist e Gateway Asterisk. (Thesis). Universidade de Lisboa. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/13864
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Henriques, Taigo Almeida. “Monitorização aplicacional - Sputnik, Checklist e Gateway Asterisk.” 2012. Thesis, Universidade de Lisboa. Accessed January 23, 2021.
http://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/13864.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Henriques, Taigo Almeida. “Monitorização aplicacional - Sputnik, Checklist e Gateway Asterisk.” 2012. Web. 23 Jan 2021.
Vancouver:
Henriques TA. Monitorização aplicacional - Sputnik, Checklist e Gateway Asterisk. [Internet] [Thesis]. Universidade de Lisboa; 2012. [cited 2021 Jan 23].
Available from: http://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/13864.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Henriques TA. Monitorização aplicacional - Sputnik, Checklist e Gateway Asterisk. [Thesis]. Universidade de Lisboa; 2012. Available from: http://www.rcaap.pt/detail.jsp?id=oai:repositorio.ul.pt:10451/13864
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Zambia
24.
Banda, Justor.
A study on prevalence and risk factors of renal dysfunction among Hospitalized HIV infected adult patients at the University Teaching Hospital, Lusaka
.
Degree: 2011, University of Zambia
URL: http://hdl.handle.net/123456789/772
► Despite the highest disease burden of HIV, Sub-Saharan Africa has limited data on HIV related kidney disease in the region. Kidney disease is a recognised…
(more)
▼ Despite the highest disease burden of HIV, Sub-Saharan Africa has limited data on HIV related kidney disease in the region. Kidney disease is a recognised complication in HIV infected patients, presenting with either can be acute renal failure (ARF) or chronic kidney disease (CKD). This study investigated the prevalence and factors associated with renal dysfunction among hospitalised HIV infected patients at the University Teaching Hospital (UTH), Lusaka.
Methodology- This was a cross sectional study that was conducted at the University Teaching Hospital Lusaka, Zambia. Enrolment of all eligible participants started from August 2010 to October, 2010. Inclusion criteria were hospitalised patients aged 16years and above who consented to the study. Qualified HIV counselors were used to counsel the patients. After obtaining demographic information, study participants were screened for HIV upon their consenting for the test. A full clinical history and examination was done by study physician to determine the factors associated with renal dysfunction.Results- Of the 300 recruited hospitalised patients in this cross sectional study, 154(51%) were males. In HIV infected patients mean SD was 35.6(9.5) and 44.1(20.0) in uninfected HIV infected subjects. Our study observed a significantly higher prevalence of renal dysfunction among hospitalised HIV infected patients (42%) compared to (27%) among uninfected HIV patients p=0.006 and 2fold increased likelihood of developing kidney dysfunction; 1.96(1.21-3.17). WHO stage III was associated with renal dysfunction in HIV infected patients. Tenofovir a first line antiretroviral drug in Zambia wasn’t associated with renal dysfunction. Mean arterial pressure (MAP) <65mmHg was not associated with kidney disease in multivariable analysis.Conclusion-Renal dysfunction is significantly higher among hospitalised HIV infected compared to uninfected patients
Subjects/Keywords: Renal failure;
Kidneys – Diseases
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APA (6th Edition):
Banda, J. (2011). A study on prevalence and risk factors of renal dysfunction among Hospitalized HIV infected adult patients at the University Teaching Hospital, Lusaka
. (Thesis). University of Zambia. Retrieved from http://hdl.handle.net/123456789/772
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Banda, Justor. “A study on prevalence and risk factors of renal dysfunction among Hospitalized HIV infected adult patients at the University Teaching Hospital, Lusaka
.” 2011. Thesis, University of Zambia. Accessed January 23, 2021.
http://hdl.handle.net/123456789/772.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Banda, Justor. “A study on prevalence and risk factors of renal dysfunction among Hospitalized HIV infected adult patients at the University Teaching Hospital, Lusaka
.” 2011. Web. 23 Jan 2021.
Vancouver:
Banda J. A study on prevalence and risk factors of renal dysfunction among Hospitalized HIV infected adult patients at the University Teaching Hospital, Lusaka
. [Internet] [Thesis]. University of Zambia; 2011. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/123456789/772.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Banda J. A study on prevalence and risk factors of renal dysfunction among Hospitalized HIV infected adult patients at the University Teaching Hospital, Lusaka
. [Thesis]. University of Zambia; 2011. Available from: http://hdl.handle.net/123456789/772
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Oregon State University
25.
Jensen, David Charles.
Design analysis using function-based failure propagation in failed system states.
Degree: MS, Mechanical Engineering, 2009, Oregon State University
URL: http://hdl.handle.net/1957/11874
► For safety critical complex systems, reliability and risk analysis are important design steps. Implementing these analyzes early in the design stage can reduce costs associated…
(more)
▼ For safety critical complex systems, reliability and risk analysis are important design steps. Implementing these analyzes early in the design stage can reduce costs associated with redesign and provide important information on design viability. In the past several years, various research methods have been presented in the design community to move reliability analysis into the early conceptual design stages. Concept stage reliability analysis faces several challenges. First, in complex systems, the integration of software and hardware into a single reliability framework is hampered by the different risk factors and behaviors of these two types of subsystems. Secondly, quantifying risk in order to make design decision is challenging when minimal technical information of the system and components is known. Finally, the current methods of conceptual design reliability analysis use a functional representation as the basis for reliability analysis. However, in non-nominal system states, the functional representation can have serious limitations. This limitation is evident when failures are modeled to propagate along energy, material, and signal (EMS) flows. A function-based reliability method must consider all potential flows, and not be limited to the function structure of the nominal state. This work introduces the Flow State Logic (FSL) method as a means for reasoning on the state of EMS flows. This method provides a means to assess
failure propagation over potential flows that were not considered in a functional representation of a “nominally functioning” design. The impact with respect to the operating state of functional elements can be calculated for these possible flow failures as well as other
failure events. The results from this type of analysis can then be used to make design decisions for integrated software-hardware, complex systems.
Advisors/Committee Members: Tumer, Irem Y. (advisor), Kurtoglu, Tolga (committee member).
Subjects/Keywords: Failure; System failures (Engineering) – Analysis
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MLA ·
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APA (6th Edition):
Jensen, D. C. (2009). Design analysis using function-based failure propagation in failed system states. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/11874
Chicago Manual of Style (16th Edition):
Jensen, David Charles. “Design analysis using function-based failure propagation in failed system states.” 2009. Masters Thesis, Oregon State University. Accessed January 23, 2021.
http://hdl.handle.net/1957/11874.
MLA Handbook (7th Edition):
Jensen, David Charles. “Design analysis using function-based failure propagation in failed system states.” 2009. Web. 23 Jan 2021.
Vancouver:
Jensen DC. Design analysis using function-based failure propagation in failed system states. [Internet] [Masters thesis]. Oregon State University; 2009. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/1957/11874.
Council of Science Editors:
Jensen DC. Design analysis using function-based failure propagation in failed system states. [Masters Thesis]. Oregon State University; 2009. Available from: http://hdl.handle.net/1957/11874

University of Pretoria
26.
[No author].
Design considerations and analysis of a bioreactor for
application in a bio-artificial liver support system
.
Degree: 2008, University of Pretoria
URL: http://upetd.up.ac.za/thesis/available/etd-04242008-093504/
► Acute Liver Failure (ALF) is a devastating ailment with a high mortality rate and limited treatment alternatives. This study presents a methodology for the design…
(more)
▼ Acute Liver
Failure (ALF) is a devastating ailment
with a high mortality rate and limited treatment alternatives. This
study presents a methodology for the design and development of a
bio-artificial bioreactor to be used in a Bio-Artificial Liver
Support System. The system will ultimately be used either to bridge
a patient to orthotopic liver transplant (OLT), the only current
cure for end stage ALF, or spontaneous recovery. Methods to
optimize and visualize the flow and related mass transfer in the BR
are presented. The use of magnetic resonance imaging (MRI),
scanning electron microscopy (SEM) and simple testing methodology
is applied with emphasis on modeling the flow conditions in the BR.
The bioreactor (BR) used in the Bio-Artificial Liver Support System
(BALSS), currently under-going animal trials at the University of
Pretoria, was modeled and simulated for the flow conditions in the
device. Two different perfusion steps were modeled including the
seeding of hepatocyte cells and later the clinical perfusion step.
It was found that the BR geometry was not optimal with “dead spots”
and regions of retarded flow. This would restrict the effective
transport of nutrients and oxygen to the cells. The different
perfusion rates for the seeding and clinical perfusion steps
allowed for different velocity contours with cells seeing
inconsistent flow patterns and mass transfer gradients. An
optimized BR design is suggested and simulated, that effectively
reduces the areas of retarded flow (dead spots) and increases the
flow speed uniformly through the BR to an order of magnitude
similar to that found in the sinusoidal range. The scaffolding
volume was also decreased to allow a larger local cell density
promoting cell-cell interaction. Finally a summarized design table
for the design of a hepatic BR is presented.
Advisors/Committee Members: Mr A J van Wyk (advisor), Prof J Meyer (advisor).
Subjects/Keywords: Bioreactor;
Acute liver failure;
UCTD
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CSE |
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Manager
APA (6th Edition):
author], [. (2008). Design considerations and analysis of a bioreactor for
application in a bio-artificial liver support system
. (Masters Thesis). University of Pretoria. Retrieved from http://upetd.up.ac.za/thesis/available/etd-04242008-093504/
Chicago Manual of Style (16th Edition):
author], [No. “Design considerations and analysis of a bioreactor for
application in a bio-artificial liver support system
.” 2008. Masters Thesis, University of Pretoria. Accessed January 23, 2021.
http://upetd.up.ac.za/thesis/available/etd-04242008-093504/.
MLA Handbook (7th Edition):
author], [No. “Design considerations and analysis of a bioreactor for
application in a bio-artificial liver support system
.” 2008. Web. 23 Jan 2021.
Vancouver:
author] [. Design considerations and analysis of a bioreactor for
application in a bio-artificial liver support system
. [Internet] [Masters thesis]. University of Pretoria; 2008. [cited 2021 Jan 23].
Available from: http://upetd.up.ac.za/thesis/available/etd-04242008-093504/.
Council of Science Editors:
author] [. Design considerations and analysis of a bioreactor for
application in a bio-artificial liver support system
. [Masters Thesis]. University of Pretoria; 2008. Available from: http://upetd.up.ac.za/thesis/available/etd-04242008-093504/

University of Alberta
27.
Pehlke, Skylar J.
Impact of Remote Telehealth on Patients with Heart Failure:
A Meta-Analysis.
Degree: Master of Nursing, Faculty of Nursing, 2016, University of Alberta
URL: https://era.library.ualberta.ca/files/c2z10wq46z
► Abstract Aims: The use of telehealth for heart failure management is increasing and it is not clear from the literature whether it is more beneficial…
(more)
▼ Abstract Aims: The use of telehealth for heart failure
management is increasing and it is not clear from the literature
whether it is more beneficial than usual care. A meta-analysis was
done of published randomized controlled trials to compare
telehealth management and usual physician care for heart failure
patients. The primary outcomes studied include mortality, hospital
readmissions and quality of life. Methods: A systematic search was
done to identify trials that met the inclusion criteria. To be
included a study had to be a randomized controlled trial published
in English with all participants diagnosed with heart failure.
Studies had to compare usual care to telehealth with at least one
of the outcomes in this analysis. Data was extracted and classified
using the AHA taxonomy for disease management and RevMan 5.3 was
used for the data analysis. All outcomes were calcu- lated using
random effects models and the quality of life outcome used the mean
difference. Results: 1548 studies were screened against the above
inclusion and exclusion criteria. This resulted in 8 randomized
controlled trials being selected for meta-analysis with individual
com- parisons for each outcome studied. Telehealth interventions
showed no significant benefits over usual care for all main
outcomes. All-cause mortality (p=0.38, 95% CI 0.69-1.16), heart
failure related hospitalizations (p=0.67, 95% CI 0.76-1.20),
all-cause rehospitalization (p=0.76, 95% CI 0.96-1.10) and quality
of life (p=0.78, 95% CI -6.59 to -4.94). Conclusions: Current
telehealth based interventions for HF self-care show no benefit
over usual care. Keywords: Heart failure, telehealth, usual care,
morbidity, mortality, quality of life, readmission.
Subjects/Keywords: heart failure; telehealth; meta-analysis
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Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Pehlke, S. J. (2016). Impact of Remote Telehealth on Patients with Heart Failure:
A Meta-Analysis. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/c2z10wq46z
Chicago Manual of Style (16th Edition):
Pehlke, Skylar J. “Impact of Remote Telehealth on Patients with Heart Failure:
A Meta-Analysis.” 2016. Masters Thesis, University of Alberta. Accessed January 23, 2021.
https://era.library.ualberta.ca/files/c2z10wq46z.
MLA Handbook (7th Edition):
Pehlke, Skylar J. “Impact of Remote Telehealth on Patients with Heart Failure:
A Meta-Analysis.” 2016. Web. 23 Jan 2021.
Vancouver:
Pehlke SJ. Impact of Remote Telehealth on Patients with Heart Failure:
A Meta-Analysis. [Internet] [Masters thesis]. University of Alberta; 2016. [cited 2021 Jan 23].
Available from: https://era.library.ualberta.ca/files/c2z10wq46z.
Council of Science Editors:
Pehlke SJ. Impact of Remote Telehealth on Patients with Heart Failure:
A Meta-Analysis. [Masters Thesis]. University of Alberta; 2016. Available from: https://era.library.ualberta.ca/files/c2z10wq46z
28.
Hao, Yilin; Tsuruda, Toshihiro; Sekita-Hatakeyama, Yoko; Kurogi, Syuji; Kubo, Keishi; Sakamoto, Sumiharu; Nakamura, Midori; Udagawa, Nobuyuki; Sekimoto, Tomohisa; Hatakeyama, Kinta; Chosa, Etsuo; Asada, Yujiro.
Cardiac hypertrophy is exacerbated in aged mice lacking the osteoprotegerin gene.
Degree: 博士(医学), 2015, University of Miyazaki / 宮崎大学
URL: http://hdl.handle.net/10458/5851
► 学位論文の一部を構成しているため、http://hdl.handle.net/10458/5850に本文を掲載。
We conducted experiments using 2.5- and 12-month-old OPG2/2 mice and age-matched wild-type (WT) mice and compared the morphology and function of the left ventricle…
(more)
▼ 学位論文の一部を構成しているため、http://hdl.handle.net/10458/5850に本文を掲載。
We conducted experiments using 2.5- and 12-month-old OPG2/2 mice and age-matched wild-type (WT) mice and compared the morphology and function of the left ventricle (LV). Both 2.5- and 12-month-old OPG2/2 mice showed a higher systolic blood pressure and a greater heart weight/body weight ratio than age-matched WT mice. Twelvemonth-old OPG2/2 mice had a significantly larger LV chamber and reduced wall thickness compared with age-matchedWT mice, and contractile function was decreased. The morphological differences were accompanied by an increase in the number of apoptotic cells and activation of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) in the LV of 12-month-old OPG2/2 mice. Correspondingly, OPG small interfering RNA induced the expressions of TRAIL and cleaved caspase-3 in cultured cardiac myocytes. In addition, these mice revealed a decrease in interstitial fibrosis, activation of matrix metalloproteinase (MMP)-2 and tissue inhibitors of MMP-1 and -2, and inactivation of procollagen a1 synthesis. Moreover, intraperitoneal administration of recombinant OPG to either 2.5- or 12- month-old OPG2/2 mice for 28 days led to partial improvement of LV structure and function without affecting systolic blood pressure.
Subjects/Keywords: Age; Hypertrophy; Heart failure; Osteoporosis
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APA (6th Edition):
Hao, Yilin; Tsuruda, Toshihiro; Sekita-Hatakeyama, Yoko; Kurogi, Syuji; Kubo, Keishi; Sakamoto, Sumiharu; Nakamura, Midori; Udagawa, Nobuyuki; Sekimoto, Tomohisa; Hatakeyama, Kinta; Chosa, Etsuo; Asada, Y. (2015). Cardiac hypertrophy is exacerbated in aged mice lacking the osteoprotegerin gene. (Thesis). University of Miyazaki / 宮崎大学. Retrieved from http://hdl.handle.net/10458/5851
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Hao, Yilin; Tsuruda, Toshihiro; Sekita-Hatakeyama, Yoko; Kurogi, Syuji; Kubo, Keishi; Sakamoto, Sumiharu; Nakamura, Midori; Udagawa, Nobuyuki; Sekimoto, Tomohisa; Hatakeyama, Kinta; Chosa, Etsuo; Asada, Yujiro. “Cardiac hypertrophy is exacerbated in aged mice lacking the osteoprotegerin gene.” 2015. Thesis, University of Miyazaki / 宮崎大学. Accessed January 23, 2021.
http://hdl.handle.net/10458/5851.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Hao, Yilin; Tsuruda, Toshihiro; Sekita-Hatakeyama, Yoko; Kurogi, Syuji; Kubo, Keishi; Sakamoto, Sumiharu; Nakamura, Midori; Udagawa, Nobuyuki; Sekimoto, Tomohisa; Hatakeyama, Kinta; Chosa, Etsuo; Asada, Yujiro. “Cardiac hypertrophy is exacerbated in aged mice lacking the osteoprotegerin gene.” 2015. Web. 23 Jan 2021.
Vancouver:
Hao, Yilin; Tsuruda, Toshihiro; Sekita-Hatakeyama, Yoko; Kurogi, Syuji; Kubo, Keishi; Sakamoto, Sumiharu; Nakamura, Midori; Udagawa, Nobuyuki; Sekimoto, Tomohisa; Hatakeyama, Kinta; Chosa, Etsuo; Asada Y. Cardiac hypertrophy is exacerbated in aged mice lacking the osteoprotegerin gene. [Internet] [Thesis]. University of Miyazaki / 宮崎大学; 2015. [cited 2021 Jan 23].
Available from: http://hdl.handle.net/10458/5851.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Hao, Yilin; Tsuruda, Toshihiro; Sekita-Hatakeyama, Yoko; Kurogi, Syuji; Kubo, Keishi; Sakamoto, Sumiharu; Nakamura, Midori; Udagawa, Nobuyuki; Sekimoto, Tomohisa; Hatakeyama, Kinta; Chosa, Etsuo; Asada Y. Cardiac hypertrophy is exacerbated in aged mice lacking the osteoprotegerin gene. [Thesis]. University of Miyazaki / 宮崎大学; 2015. Available from: http://hdl.handle.net/10458/5851
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

San Jose State University
29.
Colleluori, Marco.
Characterization of the Performance and Failure Mechanisms of the Hydrazine Propulsion System of ISEE-3.
Degree: MS, Aerospace Engineering, 2015, San Jose State University
URL: https://doi.org/10.31979/etd.c8ba-c2kk
;
https://scholarworks.sjsu.edu/etd_theses/4534
► After travelling through space dormant for 27 years, hopes were high for the reactivation of the hydrazine propulsion system on the International Sun Earth…
(more)
▼ After travelling through space dormant for 27 years, hopes were high for the reactivation of the hydrazine propulsion system on the International Sun Earth Explorer 3. While many of the onboard systems were still operational when contact was reestablished in 2014, the propulsion system was no longer able to change the spacecraft trajectory. The formulation of a single cohesive theory of how the system failed provides an opportunity to study the properties of a spacecraft that outlived its design lifetime by more than 30 years, and to apply lessons learned to future designs.
This thesis describes observations made about the performance of the propulsion system during commanding in 2014 that led to the determination that the nitrogen pressurant from the propulsion system had been lost. The focus is on the mechanism by which the pressurant disappeared between 1987 and 2014 without catastrophic failure of the spacecraft or even the loss of the majority of the fuel. Scenarios are proposed to explain these observations, and the results of simulations designed to test these scenarios are presented. Analysis of all simulations led to the conclusion that the most likely scenario accounting for system failure was a micrometeoroid impact near the bottom of the spacecraft
Subjects/Keywords: Failure; Hydrazine; ISEE-3; Propulsion
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APA ·
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MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Colleluori, M. (2015). Characterization of the Performance and Failure Mechanisms of the Hydrazine Propulsion System of ISEE-3. (Masters Thesis). San Jose State University. Retrieved from https://doi.org/10.31979/etd.c8ba-c2kk ; https://scholarworks.sjsu.edu/etd_theses/4534
Chicago Manual of Style (16th Edition):
Colleluori, Marco. “Characterization of the Performance and Failure Mechanisms of the Hydrazine Propulsion System of ISEE-3.” 2015. Masters Thesis, San Jose State University. Accessed January 23, 2021.
https://doi.org/10.31979/etd.c8ba-c2kk ; https://scholarworks.sjsu.edu/etd_theses/4534.
MLA Handbook (7th Edition):
Colleluori, Marco. “Characterization of the Performance and Failure Mechanisms of the Hydrazine Propulsion System of ISEE-3.” 2015. Web. 23 Jan 2021.
Vancouver:
Colleluori M. Characterization of the Performance and Failure Mechanisms of the Hydrazine Propulsion System of ISEE-3. [Internet] [Masters thesis]. San Jose State University; 2015. [cited 2021 Jan 23].
Available from: https://doi.org/10.31979/etd.c8ba-c2kk ; https://scholarworks.sjsu.edu/etd_theses/4534.
Council of Science Editors:
Colleluori M. Characterization of the Performance and Failure Mechanisms of the Hydrazine Propulsion System of ISEE-3. [Masters Thesis]. San Jose State University; 2015. Available from: https://doi.org/10.31979/etd.c8ba-c2kk ; https://scholarworks.sjsu.edu/etd_theses/4534
30.
Liu, Junwei.
Micro-mechanical Modeling of Brittle Materials under Dynamic Compressive Loading.
Degree: 2015, Johns Hopkins University
URL: http://jhir.library.jhu.edu/handle/1774.2/38023
► Micro-mechanical modeling of brittle dynamic failure provides a physical insight into the relationship between microstructure, which dictates key failure mechanisms, and material performance. This dissertation…
(more)
▼ Micro-mechanical modeling of brittle dynamic
failure provides a physical insight into the relationship between microstructure, which dictates key
failure mechanisms, and material performance. This dissertation addresses key issues in micromechanical models associated with brittle dynamic
failure, in particular damage-induced material anisotropy, efficiency of the micromechanics model to enable larger-scale implementation, and non-local modeling to represent strain softening materials. The dominant
failure mechanism for brittle materials under compressive loads is the growth and coalescence of wing-cracks; therefore, the micromechanics model based on wing-cracks is the focus of this work. Based on a wing-crack RVE model, analytical closed-form solutions for the instantaneous effective anisotropic compliance (or stiffness) of a damaged material under compression are derived through both kinematic and energetic approaches. These solutions are functions of the geometric
measurements of the wing-cracks and the friction coefficient. Application of the model to tensile loads is a straightforward simplification of the proposed model. Finite element models of periodic wing-cracks verify the analytical results, confirming the effectiveness of the analytical solution. Combining this anisotropic compliance with an established micro-mechanics model that addresses crack growth, the stress-strain relationship of a brittle material under compressive loading is established. In upscaling to a macro-scale computational model, this micro-mechanically based constitutive model is evaluated at each individual integration point of the mesh. For models with many integration points, this micromechanical analysis for every integration point at every time step is computationally prohibitive. An upscaling technique is proposed here to tackle this issue. Instead of repeatedly performing the complete constitutive model for each integration point, a Taylor series expansion is
applied to approximate the micromechanics damage process. Such a methodology can be deployed to enhance the efficiency of the macro-scale models as well as the statistical estimations of the local stress and strength of the material with heterogeneous nature. To the end of properly modeling the strain softening behavior at the highly damaged stage, a conventional nonlocal finite element method is investigated by simulating a series of bench mark problems.
Advisors/Committee Members: Graham-Brady, Lori (advisor).
Subjects/Keywords: Brittle Materials;
Dynamic Failure
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Liu, J. (2015). Micro-mechanical Modeling of Brittle Materials under Dynamic Compressive Loading. (Thesis). Johns Hopkins University. Retrieved from http://jhir.library.jhu.edu/handle/1774.2/38023
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Liu, Junwei. “Micro-mechanical Modeling of Brittle Materials under Dynamic Compressive Loading.” 2015. Thesis, Johns Hopkins University. Accessed January 23, 2021.
http://jhir.library.jhu.edu/handle/1774.2/38023.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Liu, Junwei. “Micro-mechanical Modeling of Brittle Materials under Dynamic Compressive Loading.” 2015. Web. 23 Jan 2021.
Vancouver:
Liu J. Micro-mechanical Modeling of Brittle Materials under Dynamic Compressive Loading. [Internet] [Thesis]. Johns Hopkins University; 2015. [cited 2021 Jan 23].
Available from: http://jhir.library.jhu.edu/handle/1774.2/38023.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Liu J. Micro-mechanical Modeling of Brittle Materials under Dynamic Compressive Loading. [Thesis]. Johns Hopkins University; 2015. Available from: http://jhir.library.jhu.edu/handle/1774.2/38023
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
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