subject:(FASD)

1. Sawant, Onkar Balkrishna. Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol.

Degree: 2013, Texas Digital Library

URL: http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66775

► Women who drink alcohol during pregnancy are at high risk of giving birth to children with physical, behavioral or cognitive developmental problems called Fetal Alcohol… (more)

▼ Women who drink alcohol during pregnancy are at high risk of giving birth to children with physical, behavioral or cognitive developmental problems called Fetal Alcohol Spectrum Disorders (FASD). Prenatal alcohol exposure is known to be associated with fetal growth restriction, disturbances in amino acid bioavailability, and alterations in fetal hemodynamics, blood flow and oxidative stress. Alterations in these parameters can persist into adolescence and low birth weight can lead to altered fetal development and programming, which can have lifelong consequences. Glutamine has been associated with fetal nitrogen and carbon metabolism, synthesis of the cellular anti-oxidant glutathione, apoptosis suppression, serving as a precursor for the synthesis of other amino acids, and increases in protein synthesis. Glutamine has been used clinically as a nutrient supplement in low birth weight infants. Therefore, it is hypothesized that repeated third trimester-equivalent maternal alcohol exposure in the sheep model decreases the bioavailability of amino acids, hampers fetal body growth, alters maternal-fetal hemodynamics, hampers uterine blood flow, alters fetal blood flow, increases cerebellar oxidative stress and that maternal L-glutamine supplementation may attenuate these negative developmental effects of prenatal alcohol exposure. Maternal alcohol exposure during the third trimester-equivalent period in the sheep model significantly reduced fetal body weight, height, crown-rump length and thoracic girth, and maternal glutamine supplementation successfully improved these fetal growth parameters in the alcohol+glutamine group. Maternal alcohol exposure during the third trimester-equivalent period resulted in significant reduction in glutamine and glutamine related amino acids bioavailability in maternal and fetal plasma as well as in the fetal amniotic and allantoic fluid. Maternal glutamine supplementation improved the bioavailability and efficacy of amino acids in the maternal and fetal compartment. This study also revealed that maternal alcohol exposure resulted in maternal acidemia, maternal hypercapnea, maternal hypoxemia as well as fetal acidemia and fetal hypercapnea, but not fetal hypoxemia. Maternal alcohol exposure during this period led to an increase in fetal mean arterial pressure, alterations in fetal brain blood flow and fetal cerebellar oxidative stress. Maternal alcohol exposure during the third trimester-equivalent period resulted in a more than 40% reduction in uterine artery blood flow. Maternal glutamine supplementation during the third trimester-equivalent period successfully attenuated the incidences of alcohol-induced maternal hypercapnea, fetal acidemia, alterations in fetal brain blood flow and improved the fetal cerebellar endogenous antioxidant status. Collectively these results signify that maternal glutamine supplementation mitigates negative developmental effects of prenatal alcohol exposure. Advisors/Committee Members: Washburn, Shannon E (advisor).

Subjects/Keywords: FASD

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APA (6^th Edition):

Sawant, O. B. (2013). Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol. (Thesis). Texas Digital Library. Retrieved from http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66775

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sawant, Onkar Balkrishna. “Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol.” 2013. Thesis, Texas Digital Library. Accessed January 16, 2021. http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66775.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sawant, Onkar Balkrishna. “Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol.” 2013. Web. 16 Jan 2021.

Vancouver:

Sawant OB. Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol. [Internet] [Thesis]. Texas Digital Library; 2013. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66775.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sawant OB. Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol. [Thesis]. Texas Digital Library; 2013. Available from: http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66775

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

2. Richard, Simone. The lived experience of foster parents in placing children in care on medication for the management of behaviors associated with fetal alcohol spectrum disorder (FASD).

Degree: Social Work, 2017, University of Manitoba

URL: http://hdl.handle.net/1993/32843

► First Nations children, in the care of Child and Family Services in Manitoba are often placed on medication for the management of behaviours associated with… (more)

Subjects/Keywords: FASD

…being placed on medications for behaviors attributed to FASD (Timimi &Taylor, 2004)… …with fetal alcohol spectrum disorder (FASD). For the purposes of this thesis the… …Naylor et al., 2007). At present, children with FASD are commonly placed on a schedule of… …FASD or ADHD, as there have been no long term studies to address their effects on children… …when pharmaceuticals are used as the main intervention for children with FASD or ADHD. They…

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Richard, S. (2017). The lived experience of foster parents in placing children in care on medication for the management of behaviors associated with fetal alcohol spectrum disorder (FASD). (Masters Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/32843

Chicago Manual of Style (16^th Edition):

Richard, Simone. “The lived experience of foster parents in placing children in care on medication for the management of behaviors associated with fetal alcohol spectrum disorder (FASD).” 2017. Masters Thesis, University of Manitoba. Accessed January 16, 2021. http://hdl.handle.net/1993/32843.

MLA Handbook (7^th Edition):

Richard, Simone. “The lived experience of foster parents in placing children in care on medication for the management of behaviors associated with fetal alcohol spectrum disorder (FASD).” 2017. Web. 16 Jan 2021.

Vancouver:

Richard S. The lived experience of foster parents in placing children in care on medication for the management of behaviors associated with fetal alcohol spectrum disorder (FASD). [Internet] [Masters thesis]. University of Manitoba; 2017. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1993/32843.

Council of Science Editors:

Richard S. The lived experience of foster parents in placing children in care on medication for the management of behaviors associated with fetal alcohol spectrum disorder (FASD). [Masters Thesis]. University of Manitoba; 2017. Available from: http://hdl.handle.net/1993/32843

Texas A&M University

3. Wang, Haiqing. Preconception Paternal Alcohol Exposure Disrupts Placental Gene Expression and Alters Chromatin Boundary Elements.

Degree: MS, Biomedical Sciences, 2017, Texas A&M University

URL: http://hdl.handle.net/1969.1/161417

► Fetal alcohol spectrum disorders (FASD) are a spectrum of pathophysiological consequences that include structural, neurological and behavior disorders that arise following prenatal alcohol exposure (PAE).… (more)

▼ Fetal alcohol spectrum disorders (FASD) are a spectrum of pathophysiological consequences that include structural, neurological and behavior disorders that arise following prenatal alcohol exposure (PAE). Work by our group and others have begun to associate alcohol-induced alterations in gene expression with heritable alterations in chromatin structure. These observations now include alterations in fetal physiology and gene expression arising from preconception paternal alcohol exposures. In this study, we hypothesized that male preconception alcohol exposure can heritably alter gene expression in placenta and that these changes in transcription are linked to alterations in the positioning of chromatin boundary elements. In this thesis, we begin to examine this assertion by characterizing patterns of gene expression and localizing chromatin boundaries between clusters of dysregulated genes. Placentas of both male and female offspring from control and alcohol-exposed fathers displayed alterations in the expression of cohorts of genes that are enriched in genetic pathways controlling aspects of molecular transport, protein synthesis, lipid metabolism, small molecule biochemistry, as well as vitamin and mineral metabolism. Importantly, many of the genes displaying alterations in gene expression localized to coregulated gene clusters, suggesting a higher order of transcriptional control was perturbed. Given the established role of DNA methylation in the control of gene expression within co-regulated clusters, we first assessed the enrichment of the methyl donor S-adenosylmethionine (SAM). These experiments did not identify any significant alterations in the levels of SAM in the paternal liver, testis, and kidney nor were we able to identify differences in the fetal brain or placenta. Further examination of chromatin structure at co-regulated promoters, enhancers and insulators within three of the most prominent gene clusters revealed that binding of the chromatin boundary protein CTCF was decreased significantly in offspring of males exposed to alcohol prior to conception. This reduced CTCF occupancy was not due to a global decrease in CTCF protein levels in placentas. These observations provided new insights in the study of male preconception alcohol abuse and the heritable impact of preconception exposures on chromatin organization. Advisors/Committee Members: Golding, Michael (advisor), Safe, Stephen (committee member), Miranda, Rajesh C (committee member).

Subjects/Keywords: paternal; FASD; CTCF

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APA (6^th Edition):

Wang, H. (2017). Preconception Paternal Alcohol Exposure Disrupts Placental Gene Expression and Alters Chromatin Boundary Elements. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/161417

Chicago Manual of Style (16^th Edition):

Wang, Haiqing. “Preconception Paternal Alcohol Exposure Disrupts Placental Gene Expression and Alters Chromatin Boundary Elements.” 2017. Masters Thesis, Texas A&M University. Accessed January 16, 2021. http://hdl.handle.net/1969.1/161417.

MLA Handbook (7^th Edition):

Wang, Haiqing. “Preconception Paternal Alcohol Exposure Disrupts Placental Gene Expression and Alters Chromatin Boundary Elements.” 2017. Web. 16 Jan 2021.

Vancouver:

Wang H. Preconception Paternal Alcohol Exposure Disrupts Placental Gene Expression and Alters Chromatin Boundary Elements. [Internet] [Masters thesis]. Texas A&M University; 2017. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1969.1/161417.

Council of Science Editors:

Wang H. Preconception Paternal Alcohol Exposure Disrupts Placental Gene Expression and Alters Chromatin Boundary Elements. [Masters Thesis]. Texas A&M University; 2017. Available from: http://hdl.handle.net/1969.1/161417

University of Alberta

4. Hutchison, Marnie Lenore. Executive Function Strategies used by Children and Adolescents with Fetal Alcohol Spectrum Disorder.

Degree: MEd, Department of Educational Psychology, 2011, University of Alberta

URL: https://era.library.ualberta.ca/files/2514nm24n

► The outcomes associated with prenatal alcohol exposure (PAE) are profound, affecting many aspects of cognitive, behavioural, and social development that can be seen in the… (more)

Subjects/Keywords: FASD; strategies; metacognition; executive function

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hutchison, M. L. (2011). Executive Function Strategies used by Children and Adolescents with Fetal Alcohol Spectrum Disorder. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/2514nm24n

Chicago Manual of Style (16^th Edition):

Hutchison, Marnie Lenore. “Executive Function Strategies used by Children and Adolescents with Fetal Alcohol Spectrum Disorder.” 2011. Masters Thesis, University of Alberta. Accessed January 16, 2021. https://era.library.ualberta.ca/files/2514nm24n.

MLA Handbook (7^th Edition):

Hutchison, Marnie Lenore. “Executive Function Strategies used by Children and Adolescents with Fetal Alcohol Spectrum Disorder.” 2011. Web. 16 Jan 2021.

Vancouver:

Hutchison ML. Executive Function Strategies used by Children and Adolescents with Fetal Alcohol Spectrum Disorder. [Internet] [Masters thesis]. University of Alberta; 2011. [cited 2021 Jan 16]. Available from: https://era.library.ualberta.ca/files/2514nm24n.

Council of Science Editors:

Hutchison ML. Executive Function Strategies used by Children and Adolescents with Fetal Alcohol Spectrum Disorder. [Masters Thesis]. University of Alberta; 2011. Available from: https://era.library.ualberta.ca/files/2514nm24n

Texas A&M University

5. Veazey, Kylee Jordan. An Epigenetic Basis to the Etiology of Fetal Alcohol Spectrum Disorders.

Degree: PhD, Genetics, 2015, Texas A&M University

URL: http://hdl.handle.net/1969.1/156462

► Observations from a number of independent laboratories indicate that ethanol has the capacity to act as a powerful epigenetic disruptor and potentially derail the process… (more)

▼ Observations from a number of independent laboratories indicate that ethanol has the capacity to act as a powerful epigenetic disruptor and potentially derail the process of cellular differentiation. The aim of this dissertation was to determine the epigenetic effects of alcohol on chromatin structure, the heritability of these effects in vitro and in vivo, and whether the severity of these alterations is tied to the differentiation state of the cell. First, we investigated the epigenetic impact of ethanol exposure in a murine neural stem cell model using chromatin immunoprecipitation, quantitative polymerase chain reaction (ChIP-qPCR) and RNA analysis. We found that two widely-studied histone modifications, trimethylated histone 3 lysine 4 (H3K4me3) and trimethylated histone 3 lysine 27 (H3K27me3), were disrupted at promoters of a panel of homeobox genes involved in neural development in the presence of alcohol, and that these disruptions do not correlate with changes in the expression of the examined genes. Second, we determined whether the disruption of chromatin structure caused by alcohol is heritable through cell division after an acute exposure in vitro. We monitored changes in H3K27me3, H3K4me3, and acetylation/demethylation of histone 3 lysine 9 (H3K9ac and H3K9me2, respectively) at the promoters of our candidate homeobox genes using ChIP-qPCR. We found that alterations in these marks persist beyond the window of exposure, and do not retain the same levels compared to controls after a recovery period in which ethanol is withdrawn. Furthermore, changes in the expression of these genes often occurred after recovery and again do not correlate with histone modifications present at their respective promoters. These alterations occur despite no indication of cell stress, but are associated with increased expression of genes involved in cell proliferation and neural lineage markers after recovery. A decrease in many oxidative stress pathway genes was also observed upon exposure that was rectified after recovery. Importantly, changes in the gene expression of histone methyltransferases and DNA methyltransferases were observed, with a concurrent change in DNA methylation. We next chose to determine if the observed alterations in chromatin structure also appear in vivo using a mouse model of early acute ethanol exposure. Pregnant dams injected with 2.9 g/kg ethanol at gestational day (GD) 7 were sacrificed at GD17, and the fetuses scored for ocular and forebrain defects. Levels of H3K27me3 were low at the promoters of many of the candidate genes in affected mice, and high levels of H3K9me2 specifically identified ethanol-affected mice, suggesting its potential as a marker for FASD phenotypes. Finally, we determined whether the epigenetic effects of ethanol are dependent on the differentiation state of the cell using a murine embryonic stem cell (ESC) model. Acute ethanol exposure resulted in oscillating changes in levels of histone modifications for a long as 10 days post-exposure. Despite these changes in… Advisors/Committee Members: Golding, Michael C (advisor), Long, Charles R (advisor), Miranda, Rajesh C (committee member), Zhou, Beiyan (committee member).

Subjects/Keywords: Epigenetics; FASD; Histone Modifications

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Veazey, K. J. (2015). An Epigenetic Basis to the Etiology of Fetal Alcohol Spectrum Disorders. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/156462

Chicago Manual of Style (16^th Edition):

Veazey, Kylee Jordan. “An Epigenetic Basis to the Etiology of Fetal Alcohol Spectrum Disorders.” 2015. Doctoral Dissertation, Texas A&M University. Accessed January 16, 2021. http://hdl.handle.net/1969.1/156462.

MLA Handbook (7^th Edition):

Veazey, Kylee Jordan. “An Epigenetic Basis to the Etiology of Fetal Alcohol Spectrum Disorders.” 2015. Web. 16 Jan 2021.

Vancouver:

Veazey KJ. An Epigenetic Basis to the Etiology of Fetal Alcohol Spectrum Disorders. [Internet] [Doctoral dissertation]. Texas A&M University; 2015. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1969.1/156462.

Council of Science Editors:

Veazey KJ. An Epigenetic Basis to the Etiology of Fetal Alcohol Spectrum Disorders. [Doctoral Dissertation]. Texas A&M University; 2015. Available from: http://hdl.handle.net/1969.1/156462

Queens University

6. Bell, Stephanie. The Prevalence of Epilepsy and Seizures in Subjects with Fetal Alcohol Spectrum Disorders .

Degree: Neuroscience Studies, 2009, Queens University

URL: http://hdl.handle.net/1974/1998

► The Prevalence of Epilepsy and Seizures in Subjects with Fetal Alcohol Spectrum Disorders. MSc Thesis, Queen’s University, Kingston, Ontario, Canada, May 2009. OBJECTIVE: Fetal alcohol… (more)

▼ The Prevalence of Epilepsy and Seizures in Subjects with Fetal Alcohol Spectrum Disorders. MSc Thesis, Queen’s University, Kingston, Ontario, Canada, May 2009. OBJECTIVE: Fetal alcohol spectrum disorders (FASD) is the umbrella term that describes the range of adverse developmental outcomes that occur in offspring as a consequence of maternal drinking during pregnancy. FASD has been associated with a large number of co-morbidities, including neurological disorders such as epilepsy. Epilepsy occurs in 0.6% of the population in Canada. The aim of this study was to evaluate the prevalence of epilepsy or seizure disorders in people who have been diagnosed with Fetal Alcohol Syndrome (FAS), partial Fetal Alcohol Syndrome (pFAS) or Alcohol Related Neurodevelopmental Disorder (ARND). METHODS: A retrospective chart review was conducted on all active charts (N=1063) at St. Michael’s Hospital (Toronto) and Glenrose Rehabilitation Hospital (Edmonton) FASD clinics. A total of 425 subjects between the ages of 2 to 49 were included in the analysis. The relationship between FASD diagnosis and other risk factors for co-occurrence of epilepsy and seizures (e.g. extent of exposure to alcohol and other drugs, type of birth, maternal history, and trauma) in subjects with FASD was also examined. Chi-square tests and multivariate multinomial logistic regression were used. RESULTS: Twenty-five (5.9%) individuals with FASD had a confirmed diagnosis of epilepsy, and 50 (11.8%) had at least one documented seizure episode, yielding an overall prevalence of 17.7% with a history of seizures in this population. Those with epilepsy or seizures were two times (Odds Ratio=2.27, 95% Confidence Interval=1.14-4.51, p<0.05) more likely to have an unnatural birth and those with epilepsy were three times (OR=3.41, 95% CI 1.11-10.5, p<0.05) more likely to have had an unnatural type of birth (breech, caesarean, forceps or vacuum) than those subjects with no history of seizures. None of the other risk factors examined were associated with a greater prevalence of epilepsy or seizures in subjects with FASD. These results indicate a remarkably high prevalence of epilepsy/seizures in the FASD population of two specialized FASD clinics compared with the general population.

Subjects/Keywords: FASD ; Epilepsy

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APA (6^th Edition):

Bell, S. (2009). The Prevalence of Epilepsy and Seizures in Subjects with Fetal Alcohol Spectrum Disorders . (Thesis). Queens University. Retrieved from http://hdl.handle.net/1974/1998

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Bell, Stephanie. “The Prevalence of Epilepsy and Seizures in Subjects with Fetal Alcohol Spectrum Disorders .” 2009. Thesis, Queens University. Accessed January 16, 2021. http://hdl.handle.net/1974/1998.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Bell, Stephanie. “The Prevalence of Epilepsy and Seizures in Subjects with Fetal Alcohol Spectrum Disorders .” 2009. Web. 16 Jan 2021.

Vancouver:

Bell S. The Prevalence of Epilepsy and Seizures in Subjects with Fetal Alcohol Spectrum Disorders . [Internet] [Thesis]. Queens University; 2009. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1974/1998.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bell S. The Prevalence of Epilepsy and Seizures in Subjects with Fetal Alcohol Spectrum Disorders . [Thesis]. Queens University; 2009. Available from: http://hdl.handle.net/1974/1998

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of New South Wales

7. McCormack, Clare. Prenatal Alcohol Exposure and Infant Cognitive Development.

Degree: National Drug & Alcohol Research Centre, 2015, University of New South Wales

URL: http://handle.unsw.edu.au/1959.4/55872 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:39571/SOURCE02?view=true

► The association between heavy prenatal alcohol exposure (PAE) and impaired cognitive development in children has been well documented, yet uncertainty remains regarding the effects of… (more)

▼ The association between heavy prenatal alcohol exposure (PAE) and impaired cognitive development in children has been well documented, yet uncertainty remains regarding the effects of low-level PAE. This thesis, after reviewing evidence in Chapter 1, and analysing that evidence (Chapter 2) addressed this issue with a particular focus on delineating effects of alcohol teratogenesis from those of associated environmental factors.In Chapter Two, the extent of intellectual impairment among children with fetal alcohol spectrum disorders (FASD) or PAE was reviewed using meta-analysis. Findings confirmed intellectual impairment occurs in FASD, quantifying the extent of this impairment across studies; no impairment was evident in children with low PAE. The remaining empirical chapters reported findings from a longitudinal pregnancy cohort study. Chapter Three examined the effect of PAE on infant cognitive development at 12-months. After adjustment for maternal IQ and environmental factors, no effect of PAE was seen on infant cognition.Chapter Four focused on the time between conception and pregnancy recognition as a unique period at high risk of PAE. Alcohol use was high during this period, with binge or heavy use being common. Analysis of trajectories of change to alcohol use showed the majority of women cease or reduce alcohol consumption following recognition of pregnancy. Factors influencing trajectory of change included age, level of alcohol consumption, tobacco and illicit substance use.Chapter Five sought to isolate effects of PAE from environmental confounders. A component of this was to examine alcohol consumption by partners, which was closely related to alcohol use by mothers. Regression analyses assessed the effect of PAE on infant cognitive outcomes, complemented by the use of propensity score matching. In no analysis was PAE at any point in pregnancy linked to poorer cognitive outcomes in children after adjustment for confounders. Together, findings herein have important implications for public health and future research. The importance of considering environmental confounders was emphasised, including the role of partners. The early period of gestation was also highlighted as being of particularly high risk for alcohol exposure, so focused research and public health interventions addressing this time period may be beneficial. Advisors/Committee Members: Mattick, Richard, National Drug & Alcohol Research Centre, Faculty of Medicine, UNSW, Hutchinson, Delyse, National Drug & Alcohol Research Centre, Faculty of Medicine, UNSW, Burns, Lucy, National Drug & Alcohol Research Centre, Faculty of Medicine, UNSW.

Subjects/Keywords: FASD; Alcohol; Pregnancy; Cognition; IQ

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APA (6^th Edition):

McCormack, C. (2015). Prenatal Alcohol Exposure and Infant Cognitive Development. (Doctoral Dissertation). University of New South Wales. Retrieved from http://handle.unsw.edu.au/1959.4/55872 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:39571/SOURCE02?view=true

Chicago Manual of Style (16^th Edition):

McCormack, Clare. “Prenatal Alcohol Exposure and Infant Cognitive Development.” 2015. Doctoral Dissertation, University of New South Wales. Accessed January 16, 2021. http://handle.unsw.edu.au/1959.4/55872 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:39571/SOURCE02?view=true.

MLA Handbook (7^th Edition):

McCormack, Clare. “Prenatal Alcohol Exposure and Infant Cognitive Development.” 2015. Web. 16 Jan 2021.

Vancouver:

McCormack C. Prenatal Alcohol Exposure and Infant Cognitive Development. [Internet] [Doctoral dissertation]. University of New South Wales; 2015. [cited 2021 Jan 16]. Available from: http://handle.unsw.edu.au/1959.4/55872 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:39571/SOURCE02?view=true.

Council of Science Editors:

McCormack C. Prenatal Alcohol Exposure and Infant Cognitive Development. [Doctoral Dissertation]. University of New South Wales; 2015. Available from: http://handle.unsw.edu.au/1959.4/55872 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:39571/SOURCE02?view=true

University of Alberta

8. Regehr, Elise. The Impact of an Intervention on Social Skills of Young Children with Prenatal Alcohol Exposure.

Degree: MEd, Department of Educational Psychology, 2014, University of Alberta

URL: https://era.library.ualberta.ca/files/ft848t145

► FASD is an umbrella term used to describe the continuum of effects that result from prenatal alcohol exposure (PAE) on the developing brain, which causes… (more)

▼ FASD is an umbrella term used to describe the continuum of effects that result from prenatal alcohol exposure (PAE) on the developing brain, which causes a multitude of behavioural impairments, including deficits in adaptive behaviours such as social skills. Although there are many interventions designed to help prevent the negative outcomes for children that result from impaired social skills for many clinical populations there is a dearth of intervention research for children with PAE or with an FASD. Therefore, the current study aimed to first, gather more information of the social profile of children with PAE or with an FASD, as well as factors that could impact social functioning and secondly, examine the effectiveness of a brief (10 half hour sessions) individualized social skills intervention for children with PAE or with an FASD. At pre-test, twenty-nine participants (14 male and 15 female; 17 with PAE and 11 with an FASD) aged 4 to 10 (M=7 years, 6 months) partook in the study (post-testing data was unavailable for one participant). Participant’s social skills and problem behaviours were evaluated and then compared to demographic information. To examine the effectiveness of the social skills intervention children with PAE or with an FASD in the social skills (n=14) were compared to matched participants in a comparison intervention (n=14). The results suggest that on average participants had significant social skills impairments and problem behaviours with a specific pattern of social skills strengths (cooperation and reduced bullying) and weaknesses (responsibility and hyperactivity). These difficulties were not significantly related to factors such as number of home placements, IQ, age, SES, sex or diagnosis. Following the social skills intervention, children’s problem behaviours decreased however, these effects when compared to the comparison intervention approached significance. Knowledge of how their social skills profile differs from other clinical populations may aid in differentiating these children from other clinical populations as well as providing tailored interventions for this population. However, more intervention research needs to be conducted to determine how to support optimal development for this population.

Subjects/Keywords: FASD; FASD, Children, Intervention, Social Skills; Intervention; Children; Social Skills

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APA (6^th Edition):

Regehr, E. (2014). The Impact of an Intervention on Social Skills of Young Children with Prenatal Alcohol Exposure. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/ft848t145

Chicago Manual of Style (16^th Edition):

Regehr, Elise. “The Impact of an Intervention on Social Skills of Young Children with Prenatal Alcohol Exposure.” 2014. Masters Thesis, University of Alberta. Accessed January 16, 2021. https://era.library.ualberta.ca/files/ft848t145.

MLA Handbook (7^th Edition):

Regehr, Elise. “The Impact of an Intervention on Social Skills of Young Children with Prenatal Alcohol Exposure.” 2014. Web. 16 Jan 2021.

Vancouver:

Regehr E. The Impact of an Intervention on Social Skills of Young Children with Prenatal Alcohol Exposure. [Internet] [Masters thesis]. University of Alberta; 2014. [cited 2021 Jan 16]. Available from: https://era.library.ualberta.ca/files/ft848t145.

Council of Science Editors:

Regehr E. The Impact of an Intervention on Social Skills of Young Children with Prenatal Alcohol Exposure. [Masters Thesis]. University of Alberta; 2014. Available from: https://era.library.ualberta.ca/files/ft848t145

University of Alberta

9. Tamana, Sukhpreet K. Mental Health Co-morbidity in Children and Adolescents with Fetal Alcohol Spectrum Disorder.

Degree: PhD, Department of Educational Psychology, 2016, University of Alberta

URL: https://era.library.ualberta.ca/files/cc247ds168

► Children and adolescents with Fetal Alcohol Spectrum Disorder (FASD) present with a range of physical, mental, behavioral, and cognitive challenges which can result in poor… (more)

▼ Children and adolescents with Fetal Alcohol Spectrum Disorder (FASD) present with a range of physical, mental, behavioral, and cognitive challenges which can result in poor long-term outcomes. Mental health issues affect over 90% of individuals with FASD and is the most common and pressing secondary problem affecting children and adolescents with FASD or prenatal alcohol exposure (PAE). I examined the pattern and rates of mental health disorders diagnosed, the role of risk and protective factors on these outcomes, and the impact of having a mental health co-morbidity upon neurobehavioral functioning in children and adolescents with FASD/PAE. In Study 1, I retrospectively examined the prenatal and postnatal risk factors associated with internalizing and externalizing mental health disorders diagnosed in a large sample of children and adolescents (n = 209) aged 3 to 17 years assessed for an FASD. Findings revealed that 54.8% of our sample were diagnosed with a mental health disorder, and up to 33.3% were at-risk for a mental health diagnosis. The most common co-morbidities reported in our sample included ADHD (46.9%, n = 98), Anxiety (10.5%, n = 22), Attachment Disorder (9.6%, n = 20), ODD or Conduct Disorder (7.7%, n = 16), PTSD (7.7%, n = 16), and Depression (6.2%, n = 13). Children with a history of 4 or more Adverse Childhood Experiences (ACEs) were at 4 times increased risk for having an internalizing mental health diagnosis. Age at assessment and exposure to abuse or neglect emerged as significant risk factors for an internalizing disorder, while sleep issues, gestational weight, drug use during pregnancy, and number of pregnancies emerged as significant risk factors for an externalizing disorder. Living in a two-parent home emerged as a protective factor associated with an externalizing disorder, whereas living in a non-fostercare placement at the time of FASD assessment, biological parent history of behavioral issues or legal issues, and lower intellectual ability, were identified as protective factors associated with an internalizing disorder. Protective factors identified in this study as being associated with positive mental health outcomes are most likely due to receiving increased supports and services. In Study 2, I compared the neurobehavioral profile of 24 children and adolescents with FASD/PAE, aged 9 to 19 years, with and without a mental health co-morbidity. Children and adolescents with a mental health co-morbidity showed trends towards greater difficulty on measures of executive function, memory and learning, attention, and behavior. Parent reported executive behavior difficulties correlated with increased behavioral problems measured on two mental health rating-scales. Results from this research have important implications for improving mental health screening and care among children and adolescents with FASD. Future directions and implications regarding mental health outcomes among children and adolescents with FASD are discussed.

Subjects/Keywords: FASD; Prenatal Alcohol Exposure; Mental Health

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Tamana, S. K. (2016). Mental Health Co-morbidity in Children and Adolescents with Fetal Alcohol Spectrum Disorder. (Doctoral Dissertation). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/cc247ds168

Chicago Manual of Style (16^th Edition):

Tamana, Sukhpreet K. “Mental Health Co-morbidity in Children and Adolescents with Fetal Alcohol Spectrum Disorder.” 2016. Doctoral Dissertation, University of Alberta. Accessed January 16, 2021. https://era.library.ualberta.ca/files/cc247ds168.

MLA Handbook (7^th Edition):

Tamana, Sukhpreet K. “Mental Health Co-morbidity in Children and Adolescents with Fetal Alcohol Spectrum Disorder.” 2016. Web. 16 Jan 2021.

Vancouver:

Tamana SK. Mental Health Co-morbidity in Children and Adolescents with Fetal Alcohol Spectrum Disorder. [Internet] [Doctoral dissertation]. University of Alberta; 2016. [cited 2021 Jan 16]. Available from: https://era.library.ualberta.ca/files/cc247ds168.

Council of Science Editors:

Tamana SK. Mental Health Co-morbidity in Children and Adolescents with Fetal Alcohol Spectrum Disorder. [Doctoral Dissertation]. University of Alberta; 2016. Available from: https://era.library.ualberta.ca/files/cc247ds168

University of Alberta

10. Rowbottom, Lisa D. A Qualitative Analysis of Counsellors’ Experiences Working with Individuals Diagnosed with FASD.

Degree: MEd, Department of Educational Psychology, 2012, University of Alberta

URL: https://era.library.ualberta.ca/files/vd66w137g

► This study used qualitative inquiry guided by phenomenology in effort to make explicit the experiences of three registered psychologists and one registered clinical social worker,… (more)

Subjects/Keywords: Fetal Alcohol Spectrum Disorder; FASD; Counselling

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APA (6^th Edition):

Rowbottom, L. D. (2012). A Qualitative Analysis of Counsellors’ Experiences Working with Individuals Diagnosed with FASD. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/vd66w137g

Chicago Manual of Style (16^th Edition):

Rowbottom, Lisa D. “A Qualitative Analysis of Counsellors’ Experiences Working with Individuals Diagnosed with FASD.” 2012. Masters Thesis, University of Alberta. Accessed January 16, 2021. https://era.library.ualberta.ca/files/vd66w137g.

MLA Handbook (7^th Edition):

Rowbottom, Lisa D. “A Qualitative Analysis of Counsellors’ Experiences Working with Individuals Diagnosed with FASD.” 2012. Web. 16 Jan 2021.

Vancouver:

Rowbottom LD. A Qualitative Analysis of Counsellors’ Experiences Working with Individuals Diagnosed with FASD. [Internet] [Masters thesis]. University of Alberta; 2012. [cited 2021 Jan 16]. Available from: https://era.library.ualberta.ca/files/vd66w137g.

Council of Science Editors:

Rowbottom LD. A Qualitative Analysis of Counsellors’ Experiences Working with Individuals Diagnosed with FASD. [Masters Thesis]. University of Alberta; 2012. Available from: https://era.library.ualberta.ca/files/vd66w137g

Texas A&M University

11. Sawant, Onkar Balkrishna. Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol.

Degree: PhD, Biomedical Sciences, 2013, Texas A&M University

URL: http://hdl.handle.net/1969.1/151882

► Women who drink alcohol during pregnancy are at high risk of giving birth to children with physical, behavioral or cognitive developmental problems called Fetal Alcohol… (more)

▼ Women who drink alcohol during pregnancy are at high risk of giving birth to children with physical, behavioral or cognitive developmental problems called Fetal Alcohol Spectrum Disorders (FASD). Prenatal alcohol exposure is known to be associated with fetal growth restriction, disturbances in amino acid bioavailability, and alterations in fetal hemodynamics, blood flow and oxidative stress. Alterations in these parameters can persist into adolescence and low birth weight can lead to altered fetal development and programming, which can have lifelong consequences. Glutamine has been associated with fetal nitrogen and carbon metabolism, synthesis of the cellular anti-oxidant glutathione, apoptosis suppression, serving as a precursor for the synthesis of other amino acids, and increases in protein synthesis. Glutamine has been used clinically as a nutrient supplement in low birth weight infants. Therefore, it is hypothesized that repeated third trimester-equivalent maternal alcohol exposure in the sheep model decreases the bioavailability of amino acids, hampers fetal body growth, alters maternal-fetal hemodynamics, hampers uterine blood flow, alters fetal blood flow, increases cerebellar oxidative stress and that maternal L-glutamine supplementation may attenuate these negative developmental effects of prenatal alcohol exposure. Maternal alcohol exposure during the third trimester-equivalent period in the sheep model significantly reduced fetal body weight, height, crown-rump length and thoracic girth, and maternal glutamine supplementation successfully improved these fetal growth parameters in the alcohol+glutamine group. Maternal alcohol exposure during the third trimester-equivalent period resulted in significant reduction in glutamine and glutamine related amino acids bioavailability in maternal and fetal plasma as well as in the fetal amniotic and allantoic fluid. Maternal glutamine supplementation improved the bioavailability and efficacy of amino acids in the maternal and fetal compartment. This study also revealed that maternal alcohol exposure resulted in maternal acidemia, maternal hypercapnea, maternal hypoxemia as well as fetal acidemia and fetal hypercapnea, but not fetal hypoxemia. Maternal alcohol exposure during this period led to an increase in fetal mean arterial pressure, alterations in fetal brain blood flow and fetal cerebellar oxidative stress. Maternal alcohol exposure during the third trimester-equivalent period resulted in a more than 40% reduction in uterine artery blood flow. Maternal glutamine supplementation during the third trimester-equivalent period successfully attenuated the incidences of alcohol-induced maternal hypercapnea, fetal acidemia, alterations in fetal brain blood flow and improved the fetal cerebellar endogenous antioxidant status. Collectively these results signify that maternal glutamine supplementation mitigates negative developmental effects of prenatal alcohol exposure. Advisors/Committee Members: Washburn, Shannon E (advisor), Wu, Guoyao (committee member), Miranda, Rajesh (committee member), Golding, Michael (committee member).

Subjects/Keywords: FASD; Teratology; Glutamine; Alcohol; Blood-flow

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sawant, O. B. (2013). Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/151882

Chicago Manual of Style (16^th Edition):

Sawant, Onkar Balkrishna. “Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol.” 2013. Doctoral Dissertation, Texas A&M University. Accessed January 16, 2021. http://hdl.handle.net/1969.1/151882.

MLA Handbook (7^th Edition):

Sawant, Onkar Balkrishna. “Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol.” 2013. Web. 16 Jan 2021.

Vancouver:

Sawant OB. Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol. [Internet] [Doctoral dissertation]. Texas A&M University; 2013. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1969.1/151882.

Council of Science Editors:

Sawant OB. Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol. [Doctoral Dissertation]. Texas A&M University; 2013. Available from: http://hdl.handle.net/1969.1/151882

Queens University

12. Sondy, Yvonne. The Effect of Prenatal Ethanol Exposure on DNA Methylation and TGF-β1, SHH and Wnt3a Transcription Regulating Factors Within the Developing Hippocampus of the Guinea Pig .

Degree: Pharmacology and Toxicology, 2012, Queens University

URL: http://hdl.handle.net/1974/7673

► One of the most frequently reported deficits seen in individuals with Fetal Alcohol Spectrum Disorder (FASD) is impairments in learning and memory, which is likely… (more)

▼ One of the most frequently reported deficits seen in individuals with Fetal Alcohol Spectrum Disorder (FASD) is impairments in learning and memory, which is likely attributed to the teratogenic effects of ethanol on the developing hippocampus. TGF-β (transforming growth factor-β), hedgehog and Wnt signaling pathways have been identified as high probability candidate pathways associated with brain deficits seen in FASD. Increasing evidence indicates that ethanol may induce changes in DNA methylation that could alter transcription regulating factors within signaling pathways critical in brain development. The purpose of this study was to test the hypotheses that prenatal ethanol exposure during i) the first trimester-equivalent period, or ii) throughout the entire gestational period induces changes in DNA methylation and alters the transcription/translation of TGF-β1, SHH (sonic hedgehog) and Wnt3a within the developing hippocampus. Pregnant Dunkin-Hartley-strain guinea pigs were assigned to one of three groups: ethanol (4 g/kg maternal body weight), isocaloric-sucrose/pair-feeding, or no treatment. Embryonic telencephalon tissue (which gives rise to the hippocampus) and fetal hippocampus were collected at gestational day (GD) 23 or GD 65, respectively. GD 23 ethanol-exposed and nutritional control embryos exhibited decreased crown-rump and head lengths. GD 65 ethanol-exposed fetuses exhibited decreased body and brain weights compared with the control groups. Ethanol exposure during the first trimester-equivalent period, but not during the entire gestational period, resulted in an increase in global DNA methylation. First trimester-equivalent ethanol exposure did not alter TGF-β1, SHH and Wnt3a gene expression within the GD 23 telencephalon. However, ethanol exposure throughout the entire pregnancy led to an increase in the expression of all three genes within the GD 65 hippocampus. No change in TGF-β1 protein was seen in the hippocampus of ethanol-treated fetuses. Post-translationally modified (ptm) SHH, but not unmodified SHH protein, was decreased in the hippocampus of ethanol-exposed fetuses. A decrease in unmodified, but not ptm Wnt3a protein, was observed in both ethanol-exposed and nutritional control hippocampus. These results suggest that prenatal ethanol exposure may affect hippocampal development through alterations in i) DNA methylation as shown at early gestation and ii) the expression of transcription regulating factors, especially SHH, as shown at term.

Subjects/Keywords: Wnt3a ; TGF-β1 ; DNA Methylation ; FASD ; SHH

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APA (6^th Edition):

Sondy, Y. (2012). The Effect of Prenatal Ethanol Exposure on DNA Methylation and TGF-β1, SHH and Wnt3a Transcription Regulating Factors Within the Developing Hippocampus of the Guinea Pig . (Thesis). Queens University. Retrieved from http://hdl.handle.net/1974/7673

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sondy, Yvonne. “The Effect of Prenatal Ethanol Exposure on DNA Methylation and TGF-β1, SHH and Wnt3a Transcription Regulating Factors Within the Developing Hippocampus of the Guinea Pig .” 2012. Thesis, Queens University. Accessed January 16, 2021. http://hdl.handle.net/1974/7673.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sondy, Yvonne. “The Effect of Prenatal Ethanol Exposure on DNA Methylation and TGF-β1, SHH and Wnt3a Transcription Regulating Factors Within the Developing Hippocampus of the Guinea Pig .” 2012. Web. 16 Jan 2021.

Vancouver:

Sondy Y. The Effect of Prenatal Ethanol Exposure on DNA Methylation and TGF-β1, SHH and Wnt3a Transcription Regulating Factors Within the Developing Hippocampus of the Guinea Pig . [Internet] [Thesis]. Queens University; 2012. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1974/7673.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sondy Y. The Effect of Prenatal Ethanol Exposure on DNA Methylation and TGF-β1, SHH and Wnt3a Transcription Regulating Factors Within the Developing Hippocampus of the Guinea Pig . [Thesis]. Queens University; 2012. Available from: http://hdl.handle.net/1974/7673

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Otago

13. Bagley, Kerryn. Fetal alcohol spectrum disorder diagnosis and intervention: An investigation of professional practice in New Zealand .

Degree: 2013, University of Otago

URL: http://hdl.handle.net/10523/4366

► Fetal alcohol spectrum disorder (FASD) is an umbrella term used to describe a range of neurodevelopmental and physical impairments associated with prenatal alcohol exposure. It… (more)

▼ Fetal alcohol spectrum disorder (FASD) is an umbrella term used to describe a range of neurodevelopmental and physical impairments associated with prenatal alcohol exposure. It is a brain-based disability which manifests in behavioural symptoms and cognitive deficits that adversely impact on the affected individual and their family. While FASD has been acknowledged as a disorder since the 1970s, it remains poorly understood in the New Zealand context, and does not attract much support from health and allied health services. Meanwhile, the normalization of alcohol in New Zealand culture affects the ways in which FASD is approached and perceived by medical specialists and lay people alike. This thesis investigates the ways in which professionals within health, allied health and social service systems in New Zealand encounter, approach and manage FASD and cases of suspected FASD. It examines the circumstances surrounding diagnosis of and intervention for FASD in New Zealand, and the factors that inform professional practice in these two fields. It questions how FASD fits within specific professional practice contexts, how social and cultural forces influence the actions of professionals, and what barriers may exist in FASD-related practice. It aims to provide a nuanced analysis of how FASD is currently handled, and suggests potential strategies for achieving more effective service provision for FASD. The research presented in this thesis is theoretically and methodologically grounded in applied medical anthropology, involving extensive participant- observation fieldwork in health and allied health training contexts in New Zealand and internationally. Over thirty in-depth semi-structured interviews were carried out with health, allied health and social service professionals in New Zealand. This data has been subjected to a thematic analysis that informs the scope of the research discussion, and provides the basis for my conclusions. Based on this data, my research suggests that professionals do indeed come into contact with cases of prenatal alcohol exposure in their work, and that many have developed innovative strategies for assisting individuals with confirmed or suspected FASD, but continue to face systemic and social barriers to achieving best practice in this area. Advisors/Committee Members: Fitzgerald, Ruth (advisor).

Subjects/Keywords: FASD; Fetal Alcohol Spectrum Disorder; Diagnosis; Intervention

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Bagley, K. (2013). Fetal alcohol spectrum disorder diagnosis and intervention: An investigation of professional practice in New Zealand . (Doctoral Dissertation). University of Otago. Retrieved from http://hdl.handle.net/10523/4366

Chicago Manual of Style (16^th Edition):

Bagley, Kerryn. “Fetal alcohol spectrum disorder diagnosis and intervention: An investigation of professional practice in New Zealand .” 2013. Doctoral Dissertation, University of Otago. Accessed January 16, 2021. http://hdl.handle.net/10523/4366.

MLA Handbook (7^th Edition):

Bagley, Kerryn. “Fetal alcohol spectrum disorder diagnosis and intervention: An investigation of professional practice in New Zealand .” 2013. Web. 16 Jan 2021.

Vancouver:

Bagley K. Fetal alcohol spectrum disorder diagnosis and intervention: An investigation of professional practice in New Zealand . [Internet] [Doctoral dissertation]. University of Otago; 2013. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/10523/4366.

Council of Science Editors:

Bagley K. Fetal alcohol spectrum disorder diagnosis and intervention: An investigation of professional practice in New Zealand . [Doctoral Dissertation]. University of Otago; 2013. Available from: http://hdl.handle.net/10523/4366

Virginia Commonwealth University

14. Culshaw, Mary. Individuals with Fetal Alcohol Spectrum Disorder: Predictive Factors for Successful Occupational Performance.

Degree: PhD, Health Related Sciences, 2015, Virginia Commonwealth University

URL: https://doi.org/10.25772/C438-KN84 ; https://scholarscompass.vcu.edu/etd/4074

► As awareness and diagnoses of FASD grow in Canada, there is increased need to support these individuals across their lifespan. One study suggested the… (more)

▼ As awareness and diagnoses of FASD grow in Canada, there is increased need to support these individuals across their lifespan. One study suggested the prevalence of FASD may be as high as 10 per 1000 births (May & Gossage, 2001). The impact to society is growing as well, since this population requires support across their lifespan due to cognitive and sometimes physical impairments. It was estimated that the annual cost to Canadians was $53 billion (in 2007 dollar value) to support individuals aged 0-53 years (Stade et al., 2009). There is mounting evidence identifying the cognitive and physical impairments that these individuals have, particularly in children. Studies have also described the adaptive functioning of children with FASD, and their ability to cope in daily life. There is little information on youth and adults regarding their daily lives, and the factors that contribute to success in daily life. The purpose of this study was to identify predictive factors that contribute to success in occupational performance in youth and adults with FASD. Using the Canadian Model of Occupational Performance and Engagement (CMOP-E), the study explored variables reflecting the person, environment, and activity that promoted engagement and participation. The study also investigated the value of using self-report or performance-based assessment with the FASD youth and adult population. Due to memory, cognitive, and executive functioning deficits, the individual with FASD may not be able to accurately self-report. Results from the study suggest an individual’s living situation, involvement with foster care, and family involvement play a role in successful occupational performance. Formal assessments of cognitive, academic and memory abilities did not appear to play a role in the individual’s school completion and daily life. Interestingly, the characteristics of this FASD sample depicted a group of youth and adults, who, in general, lived with family, had completed some schooling at the grade 10-12 level, had limited employment, were not involved with the judicial system, and were just as likely to be Caucasian as Aboriginal. The concept of occupational performance proved complex, and future study on the factors contributing to occupational performance would benefit from additional variables related to environment and activity than were available in the current data set. Advisors/Committee Members: Dr. Shelly Lane, Dr. Tracy Jirikowic, Dr. Henry Caretta, Dr. Dianne F. Simons.

Subjects/Keywords: fetal alcohol; occupational performance; FASD; Occupational Therapy

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APA (6^th Edition):

Culshaw, M. (2015). Individuals with Fetal Alcohol Spectrum Disorder: Predictive Factors for Successful Occupational Performance. (Doctoral Dissertation). Virginia Commonwealth University. Retrieved from https://doi.org/10.25772/C438-KN84 ; https://scholarscompass.vcu.edu/etd/4074

Chicago Manual of Style (16^th Edition):

Culshaw, Mary. “Individuals with Fetal Alcohol Spectrum Disorder: Predictive Factors for Successful Occupational Performance.” 2015. Doctoral Dissertation, Virginia Commonwealth University. Accessed January 16, 2021. https://doi.org/10.25772/C438-KN84 ; https://scholarscompass.vcu.edu/etd/4074.

MLA Handbook (7^th Edition):

Culshaw, Mary. “Individuals with Fetal Alcohol Spectrum Disorder: Predictive Factors for Successful Occupational Performance.” 2015. Web. 16 Jan 2021.

Vancouver:

Culshaw M. Individuals with Fetal Alcohol Spectrum Disorder: Predictive Factors for Successful Occupational Performance. [Internet] [Doctoral dissertation]. Virginia Commonwealth University; 2015. [cited 2021 Jan 16]. Available from: https://doi.org/10.25772/C438-KN84 ; https://scholarscompass.vcu.edu/etd/4074.

Council of Science Editors:

Culshaw M. Individuals with Fetal Alcohol Spectrum Disorder: Predictive Factors for Successful Occupational Performance. [Doctoral Dissertation]. Virginia Commonwealth University; 2015. Available from: https://doi.org/10.25772/C438-KN84 ; https://scholarscompass.vcu.edu/etd/4074

University of Manitoba

15. Giesbrecht, Heather. Laying the groundwork for prenatal dietary assessment research among First Nations women at risk for alcohol use: Implications for Fetal Alcohol Spectrum Disorder.

Degree: Human Nutritional Sciences, 2015, University of Manitoba

URL: http://hdl.handle.net/1993/30682

► Fetal Alcohol Spectrum Disorder (FASD) is a health concern that is over-represented among First Nations peoples. Optimal prenatal nutrition plays a role in the severity… (more)

Subjects/Keywords: FASD; Prenatal nutrition; First Nations; Research tool

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Giesbrecht, H. (2015). Laying the groundwork for prenatal dietary assessment research among First Nations women at risk for alcohol use: Implications for Fetal Alcohol Spectrum Disorder. (Masters Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/30682

Chicago Manual of Style (16^th Edition):

Giesbrecht, Heather. “Laying the groundwork for prenatal dietary assessment research among First Nations women at risk for alcohol use: Implications for Fetal Alcohol Spectrum Disorder.” 2015. Masters Thesis, University of Manitoba. Accessed January 16, 2021. http://hdl.handle.net/1993/30682.

MLA Handbook (7^th Edition):

Giesbrecht, Heather. “Laying the groundwork for prenatal dietary assessment research among First Nations women at risk for alcohol use: Implications for Fetal Alcohol Spectrum Disorder.” 2015. Web. 16 Jan 2021.

Vancouver:

Giesbrecht H. Laying the groundwork for prenatal dietary assessment research among First Nations women at risk for alcohol use: Implications for Fetal Alcohol Spectrum Disorder. [Internet] [Masters thesis]. University of Manitoba; 2015. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1993/30682.

Council of Science Editors:

Giesbrecht H. Laying the groundwork for prenatal dietary assessment research among First Nations women at risk for alcohol use: Implications for Fetal Alcohol Spectrum Disorder. [Masters Thesis]. University of Manitoba; 2015. Available from: http://hdl.handle.net/1993/30682

University of Manitoba

16. Woods Frohlich, Lindsay. Distinguishing alcohol related neurodevelopmental disorder from attention-deficit/hyperactivity disorder using psychological measures and fMRI.

Degree: Psychology, 2016, University of Manitoba

URL: http://hdl.handle.net/1993/31720

► Individuals with Alcohol Related Neurodevelopmental Disorder (ARND) and Attention-Deficit/Hyperactivity Disorder (ADHD) display similar deficits in behavioural, cognitive, and executive dysfunction symptoms; however, the underlying impairment… (more)

▼ Individuals with Alcohol Related Neurodevelopmental Disorder (ARND) and Attention-Deficit/Hyperactivity Disorder (ADHD) display similar deficits in behavioural, cognitive, and executive dysfunction symptoms; however, the underlying impairment in brain function and attention pathways is thought to be different. This study compared these two clinical groups, and healthy controls, using psychological assessments and functional magnetic resonance imaging (fMRI). The two clinical groups had significantly different scores on measures of overall intellectual functioning, working memory, and the conjunction trials on the fMRI assessment but could not be differentiated on other measures from rating scales, standardized psychological assessments, and performance data from fMRI tasks. The fMRI task accuracy variables were strongly correlated with related standardized psychological measures. All groups demonstrated difficulties with response inhibition compared to attention, and the clinical groups demonstrated more difficulties with attention and variability compared to the control group on a computer-paced Go/No-Go task. The comparison of a self-paced and a computer-paced Go/No-Go task indicated that the computer-paced task would be more appropriate to use with fMRI to assess cortical activation in response inhibition. It was found that the ADHD group had higher levels of cortical activation (indicating that more cognitive effort was require to reach the same level of behavioural performance) compared to the ARND group during the visual-spatial attention tasks, whereas the ARND group had higher levels of activation during the response inhibition and working memory tasks. Despite no significant differences in behavioural performance, the fMRI tasks helped to demonstrate different activation patterns that could help distinguish and differentially diagnose these two similar groups. Advisors/Committee Members: Pear, Joseph (Psychology) (supervisor), Clancy, Christine (Psychology) Yu, C.T. (Psychology) Chudley, Albert (Biochemistry and Medical Genetics) Beaulieu, Christian (University of Alberta) (examiningcommittee).

Subjects/Keywords: FASD; ARND; ADHD; Functional magnetic resonance imaging

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APA (6^th Edition):

Woods Frohlich, L. (2016). Distinguishing alcohol related neurodevelopmental disorder from attention-deficit/hyperactivity disorder using psychological measures and fMRI. (Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/31720

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Woods Frohlich, Lindsay. “Distinguishing alcohol related neurodevelopmental disorder from attention-deficit/hyperactivity disorder using psychological measures and fMRI.” 2016. Thesis, University of Manitoba. Accessed January 16, 2021. http://hdl.handle.net/1993/31720.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Woods Frohlich, Lindsay. “Distinguishing alcohol related neurodevelopmental disorder from attention-deficit/hyperactivity disorder using psychological measures and fMRI.” 2016. Web. 16 Jan 2021.

Vancouver:

Woods Frohlich L. Distinguishing alcohol related neurodevelopmental disorder from attention-deficit/hyperactivity disorder using psychological measures and fMRI. [Internet] [Thesis]. University of Manitoba; 2016. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1993/31720.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Woods Frohlich L. Distinguishing alcohol related neurodevelopmental disorder from attention-deficit/hyperactivity disorder using psychological measures and fMRI. [Thesis]. University of Manitoba; 2016. Available from: http://hdl.handle.net/1993/31720

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Cape Town

17. Coetzee, Lian-Marie. Mothers’ facilitation of the occupational engagement of their children with FASD: a qualitative descriptive study in an under-resourced district in South Africa.

Degree: MSc, Health and Rehabilitation Sciences, 2019, University of Cape Town

URL: http://hdl.handle.net/11427/31642

► South Africa has the highest reported prevalence of Fetal Alcohol Spectrum Disorder (FASD) worldwide. The high prevalence is aggravated by limited remedial and rehabilitative services… (more)

Subjects/Keywords: FASD; caregivers; facilitation of occupational engagement

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APA (6^th Edition):

Coetzee, L. (2019). Mothers’ facilitation of the occupational engagement of their children with FASD: a qualitative descriptive study in an under-resourced district in South Africa. (Masters Thesis). University of Cape Town. Retrieved from http://hdl.handle.net/11427/31642

Chicago Manual of Style (16^th Edition):

Coetzee, Lian-Marie. “Mothers’ facilitation of the occupational engagement of their children with FASD: a qualitative descriptive study in an under-resourced district in South Africa.” 2019. Masters Thesis, University of Cape Town. Accessed January 16, 2021. http://hdl.handle.net/11427/31642.

MLA Handbook (7^th Edition):

Coetzee, Lian-Marie. “Mothers’ facilitation of the occupational engagement of their children with FASD: a qualitative descriptive study in an under-resourced district in South Africa.” 2019. Web. 16 Jan 2021.

Vancouver:

Coetzee L. Mothers’ facilitation of the occupational engagement of their children with FASD: a qualitative descriptive study in an under-resourced district in South Africa. [Internet] [Masters thesis]. University of Cape Town; 2019. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/11427/31642.

Council of Science Editors:

Coetzee L. Mothers’ facilitation of the occupational engagement of their children with FASD: a qualitative descriptive study in an under-resourced district in South Africa. [Masters Thesis]. University of Cape Town; 2019. Available from: http://hdl.handle.net/11427/31642

University of New Mexico

18. Garcia, Christopher M. FRONTAL PARIETAL NETWORK FUNCTION DURING A VISUOMOTOR TASK IN FETAL ALCOHOL SPECTRUM DISORDER: A MAGNETOENCEPHALOGRAPHY STUDY.

Degree: Psychology, 2016, University of New Mexico

URL: http://hdl.handle.net/1928/32241

► Exposure to alcohol in utero produces a range of morphological and functional outcomes called fetal alcohol spectrum disorders (FASD). Children with FASD exhibit a broad… (more)

Subjects/Keywords: MEG; FASD; finger tapping; frontal parietal network

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APA (6^th Edition):

Garcia, C. M. (2016). FRONTAL PARIETAL NETWORK FUNCTION DURING A VISUOMOTOR TASK IN FETAL ALCOHOL SPECTRUM DISORDER: A MAGNETOENCEPHALOGRAPHY STUDY. (Masters Thesis). University of New Mexico. Retrieved from http://hdl.handle.net/1928/32241

Chicago Manual of Style (16^th Edition):

Garcia, Christopher M. “FRONTAL PARIETAL NETWORK FUNCTION DURING A VISUOMOTOR TASK IN FETAL ALCOHOL SPECTRUM DISORDER: A MAGNETOENCEPHALOGRAPHY STUDY.” 2016. Masters Thesis, University of New Mexico. Accessed January 16, 2021. http://hdl.handle.net/1928/32241.

MLA Handbook (7^th Edition):

Garcia, Christopher M. “FRONTAL PARIETAL NETWORK FUNCTION DURING A VISUOMOTOR TASK IN FETAL ALCOHOL SPECTRUM DISORDER: A MAGNETOENCEPHALOGRAPHY STUDY.” 2016. Web. 16 Jan 2021.

Vancouver:

Garcia CM. FRONTAL PARIETAL NETWORK FUNCTION DURING A VISUOMOTOR TASK IN FETAL ALCOHOL SPECTRUM DISORDER: A MAGNETOENCEPHALOGRAPHY STUDY. [Internet] [Masters thesis]. University of New Mexico; 2016. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1928/32241.

Council of Science Editors:

Garcia CM. FRONTAL PARIETAL NETWORK FUNCTION DURING A VISUOMOTOR TASK IN FETAL ALCOHOL SPECTRUM DISORDER: A MAGNETOENCEPHALOGRAPHY STUDY. [Masters Thesis]. University of New Mexico; 2016. Available from: http://hdl.handle.net/1928/32241

University of New Mexico

19. Rodriguez, Carlos I. The effects of prenatal alcohol exposure on the resting state functional brain connectivity in a sample of individuals with fetal alcohol spectrum disorder.

Degree: Psychology, 2018, University of New Mexico

URL: https://digitalrepository.unm.edu/psy_etds/259

► It is well established that alcohol exposure during prenatal development can lead to a heterogeneous and wide ranging set of morphological and neurobehavioral deficits… (more)

Subjects/Keywords: FASD; Prenatal Alcohol Exposure; Functional Connectivity; Psychology

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APA (6^th Edition):

Rodriguez, C. I. (2018). The effects of prenatal alcohol exposure on the resting state functional brain connectivity in a sample of individuals with fetal alcohol spectrum disorder. (Doctoral Dissertation). University of New Mexico. Retrieved from https://digitalrepository.unm.edu/psy_etds/259

Chicago Manual of Style (16^th Edition):

Rodriguez, Carlos I. “The effects of prenatal alcohol exposure on the resting state functional brain connectivity in a sample of individuals with fetal alcohol spectrum disorder.” 2018. Doctoral Dissertation, University of New Mexico. Accessed January 16, 2021. https://digitalrepository.unm.edu/psy_etds/259.

MLA Handbook (7^th Edition):

Rodriguez, Carlos I. “The effects of prenatal alcohol exposure on the resting state functional brain connectivity in a sample of individuals with fetal alcohol spectrum disorder.” 2018. Web. 16 Jan 2021.

Vancouver:

Rodriguez CI. The effects of prenatal alcohol exposure on the resting state functional brain connectivity in a sample of individuals with fetal alcohol spectrum disorder. [Internet] [Doctoral dissertation]. University of New Mexico; 2018. [cited 2021 Jan 16]. Available from: https://digitalrepository.unm.edu/psy_etds/259.

Council of Science Editors:

Rodriguez CI. The effects of prenatal alcohol exposure on the resting state functional brain connectivity in a sample of individuals with fetal alcohol spectrum disorder. [Doctoral Dissertation]. University of New Mexico; 2018. Available from: https://digitalrepository.unm.edu/psy_etds/259

Laurentian University

20. Geddes, Angela. FASD: moving toward sustainable assessment and support services in Ontario.

Degree: 2015, Laurentian University

URL: https://zone.biblio.laurentian.ca/dspace/handle/10219/2517

► Neurological, physical and developmental impairments resulting from prenatal alcohol exposure (PAE) fall along a spectrum and under the umbrella term Fetal Alcohol Spectrum Disorders (FASD).… (more)

Subjects/Keywords: Fetal Alcohol Spectrum Disorders (FASD); Prenatal Alcohol Exposure (PAE); Diagnosis; Prevention; Holistic care; FASD informed approaches; Capacity building

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APA (6^th Edition):

Geddes, A. (2015). FASD: moving toward sustainable assessment and support services in Ontario. (Thesis). Laurentian University. Retrieved from https://zone.biblio.laurentian.ca/dspace/handle/10219/2517

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Geddes, Angela. “FASD: moving toward sustainable assessment and support services in Ontario. ” 2015. Thesis, Laurentian University. Accessed January 16, 2021. https://zone.biblio.laurentian.ca/dspace/handle/10219/2517.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Geddes, Angela. “FASD: moving toward sustainable assessment and support services in Ontario. ” 2015. Web. 16 Jan 2021.

Vancouver:

Geddes A. FASD: moving toward sustainable assessment and support services in Ontario. [Internet] [Thesis]. Laurentian University; 2015. [cited 2021 Jan 16]. Available from: https://zone.biblio.laurentian.ca/dspace/handle/10219/2517.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Geddes A. FASD: moving toward sustainable assessment and support services in Ontario. [Thesis]. Laurentian University; 2015. Available from: https://zone.biblio.laurentian.ca/dspace/handle/10219/2517

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Dalhousie University

21. Bojkovsky, Cynthia. WHAT ARE THE IMPRESSIONS OF OCCUPATIONAL THERAPISTS WHO USE THE SHORT SENSORY PROFILE IN ASSESSMENTS FOR DIAGNOSIS OF FETAL ALCOHOL SPECTRUM DISORDERS?.

Degree: MS, School of Occupational Therapy, 2010, Dalhousie University

URL: http://hdl.handle.net/10222/13161

► Introduction: The Canadian Medical Association (CMA) released guidelines for Fetal Alcohol Spectrum Diagnosis (FASD) in 2005 that attempted to equalize diagnostic practices across Canada. A… (more)

▼ Introduction: The Canadian Medical Association (CMA) released guidelines for Fetal Alcohol Spectrum Diagnosis (FASD) in 2005 that attempted to equalize diagnostic practices across Canada. A multi-disciplinary neurodevelopmental assessment is expected and the occupational therapist must assess soft neurological signs, which includes sensory processing and motor development. In 2007, Northwest Partnership for FASD Research gathered a panel of OTs to consult on assessment tools who chose the Short Sensory Profile (SSP) as the main sensory processing assessment tool. Methods: Six qualitative interviews were completed for data collection. The inclusion criterion for the participants were involvement with a FASD diagnostic team and familiarity with the SSP. Qualitative data from the interviews was coded for likeness and analyzed for themes. Results: Three main themes developed from this research including: “Uncertainties about the FASD Diagnostic Process”, “Questioning the Validity of the Assessment Tool SSP” and “Strengths of the SSP”. The overaching theme that emerged was that the participants were attempting to find balance in many different ways throughout their assessments. While participants predominantly focused on concerns, they also indicated that the SSP is our best option at this time. Conclusions: Participants were not completely satisfied with using the SSP for FASD diagnostic assessments but will continue to use it. It was suggested that the panel of occupational therapists should reconvene and consider further options for assessment of sensory processing for FASD diagnostic assessments. There were also considerations for occupational therapy university education and continuing education. Advisors/Committee Members: Dr. Brenda Merrit (external-examiner), Dr. Robin Stadnyk (graduate-coordinator), Dr. Grace Warner (thesis-reader), Dr. Joan Versnel (thesis-supervisor), Received (ethics-approval), No (manuscripts), Not Applicable (copyright-release).

Subjects/Keywords: FASD; SENSORY PROCESSING; SHORT SENSORY PROFILE; OCCUPATIONAL THERAPY

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APA (6^th Edition):

Bojkovsky, C. (2010). WHAT ARE THE IMPRESSIONS OF OCCUPATIONAL THERAPISTS WHO USE THE SHORT SENSORY PROFILE IN ASSESSMENTS FOR DIAGNOSIS OF FETAL ALCOHOL SPECTRUM DISORDERS?. (Masters Thesis). Dalhousie University. Retrieved from http://hdl.handle.net/10222/13161

Chicago Manual of Style (16^th Edition):

Bojkovsky, Cynthia. “WHAT ARE THE IMPRESSIONS OF OCCUPATIONAL THERAPISTS WHO USE THE SHORT SENSORY PROFILE IN ASSESSMENTS FOR DIAGNOSIS OF FETAL ALCOHOL SPECTRUM DISORDERS?.” 2010. Masters Thesis, Dalhousie University. Accessed January 16, 2021. http://hdl.handle.net/10222/13161.

MLA Handbook (7^th Edition):

Bojkovsky, Cynthia. “WHAT ARE THE IMPRESSIONS OF OCCUPATIONAL THERAPISTS WHO USE THE SHORT SENSORY PROFILE IN ASSESSMENTS FOR DIAGNOSIS OF FETAL ALCOHOL SPECTRUM DISORDERS?.” 2010. Web. 16 Jan 2021.

Vancouver:

Bojkovsky C. WHAT ARE THE IMPRESSIONS OF OCCUPATIONAL THERAPISTS WHO USE THE SHORT SENSORY PROFILE IN ASSESSMENTS FOR DIAGNOSIS OF FETAL ALCOHOL SPECTRUM DISORDERS?. [Internet] [Masters thesis]. Dalhousie University; 2010. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/10222/13161.

Council of Science Editors:

Bojkovsky C. WHAT ARE THE IMPRESSIONS OF OCCUPATIONAL THERAPISTS WHO USE THE SHORT SENSORY PROFILE IN ASSESSMENTS FOR DIAGNOSIS OF FETAL ALCOHOL SPECTRUM DISORDERS?. [Masters Thesis]. Dalhousie University; 2010. Available from: http://hdl.handle.net/10222/13161

University of California – San Diego

22. Glass, Leila. Characterizing Reading Ability in Children with Prenatal Alcohol Exposure.

Degree: Clin Psychology (Jnt Doc SDSU), 2016, University of California – San Diego

URL: http://www.escholarship.org/uc/item/9cr6b0r3

► Despite widespread public health campaigns and increased knowledge of the harmful effects of drinking during pregnancy, greater than 1% of children are estimated to have… (more)

▼ Despite widespread public health campaigns and increased knowledge of the harmful effects of drinking during pregnancy, greater than 1% of children are estimated to have prenatal alcohol exposure. Reading-related difficulties are of particular concern in the school-age population. The current study aimed to characterize reading performance in children with heavy prenatal alcohol exposure.Children (6–12y) with histories of heavy prenatal alcohol exposure (n=32) and without (n=40) were administered a two-hour neuropsychological battery, which included multiple measures of reading domains (decoding, fluency, comprehension) and phonological processing (phonological awareness, phonological memory, rapid naming). Caregivers completed assessments of home literacy environment and behavior. Correlation, MANOVA, and regression techniques were conducted to evaluate differences between groups and identify contributing factors for reading performance. Discriminant function and latent class analyses were run to determine whether performance on these measures could aid in differential diagnosis and establish whether distinct subtypes of reading impairment exist.There were no significant differences on demographic characteristics between groups. Alcohol-exposed children performed significantly worse than their peers on all measures, with the exception of rapid naming. In particular, alcohol-exposed children had relative weaknesses in phonological awareness, decoding, and comprehension. They also had significantly higher rates of reading difficulties in all domains. Aspects of phonological processing accounted for significant variance in reading variables across groups. Exposure history accounted for additional variance in decoding and comprehension. No interaction effects were significant. After other factors were added to the models, vocabulary, behavioral concerns, and attitude towards reading were additional significant contributors. Also, exposure history continued to account for significant variance. Outcome variables distinguished between alcohol-exposed children and controls. Distinct subgroups emerged based on severity of impairment. There were no significant differences between performances on academic domains (reading, spelling, math) for either group.Alcohol-exposed children had significant difficulties in all aspects of reading, comparable with their performance in math and spelling. They demonstrated specific weaknesses that suggest potential targets for intervention. Cognitive mechanisms that contribute to reading in both typical and neurodevelopmental disorder populations were also found in this population. Therefore, effective interventions in other populations may be utilized to improve outcomes for alcohol-exposed children.

Subjects/Keywords: Clinical psychology; Academic Achievement; Education; FAS; FASD; Prenatal Alcohol Exposure; Psychology

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APA (6^th Edition):

Glass, L. (2016). Characterizing Reading Ability in Children with Prenatal Alcohol Exposure. (Thesis). University of California – San Diego. Retrieved from http://www.escholarship.org/uc/item/9cr6b0r3

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Glass, Leila. “Characterizing Reading Ability in Children with Prenatal Alcohol Exposure.” 2016. Thesis, University of California – San Diego. Accessed January 16, 2021. http://www.escholarship.org/uc/item/9cr6b0r3.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Glass, Leila. “Characterizing Reading Ability in Children with Prenatal Alcohol Exposure.” 2016. Web. 16 Jan 2021.

Vancouver:

Glass L. Characterizing Reading Ability in Children with Prenatal Alcohol Exposure. [Internet] [Thesis]. University of California – San Diego; 2016. [cited 2021 Jan 16]. Available from: http://www.escholarship.org/uc/item/9cr6b0r3.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Glass L. Characterizing Reading Ability in Children with Prenatal Alcohol Exposure. [Thesis]. University of California – San Diego; 2016. Available from: http://www.escholarship.org/uc/item/9cr6b0r3

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Alberta

23. Hutchison, Marnie L. Integrating Effective and Feasible FASD Programming in Schools: An Executive Function Intervention.

Degree: PhD, Department of Educational Psychology, 2015, University of Alberta

URL: https://era.library.ualberta.ca/files/j098zd82c

► Developing appropriate and accessible services for individuals with fetal alcohol spectrum disorder (FASD) is a priority for caregivers and service providers, especially schools. For this… (more)

Subjects/Keywords: fetal alcohol spectrum disorde; school; fasd; executive function; intervention

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APA (6^th Edition):

Hutchison, M. L. (2015). Integrating Effective and Feasible FASD Programming in Schools: An Executive Function Intervention. (Doctoral Dissertation). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/j098zd82c

Chicago Manual of Style (16^th Edition):

Hutchison, Marnie L. “Integrating Effective and Feasible FASD Programming in Schools: An Executive Function Intervention.” 2015. Doctoral Dissertation, University of Alberta. Accessed January 16, 2021. https://era.library.ualberta.ca/files/j098zd82c.

MLA Handbook (7^th Edition):

Hutchison, Marnie L. “Integrating Effective and Feasible FASD Programming in Schools: An Executive Function Intervention.” 2015. Web. 16 Jan 2021.

Vancouver:

Hutchison ML. Integrating Effective and Feasible FASD Programming in Schools: An Executive Function Intervention. [Internet] [Doctoral dissertation]. University of Alberta; 2015. [cited 2021 Jan 16]. Available from: https://era.library.ualberta.ca/files/j098zd82c.

Council of Science Editors:

Hutchison ML. Integrating Effective and Feasible FASD Programming in Schools: An Executive Function Intervention. [Doctoral Dissertation]. University of Alberta; 2015. Available from: https://era.library.ualberta.ca/files/j098zd82c

University of Toronto

24. Goril, Shery. The Patterns of Sleep Disorders and Circadian Rhythm Disruptions in Children and Adolescents with Fetal Alcohol Spectrum Disorders.

Degree: 2011, University of Toronto

URL: http://hdl.handle.net/1807/30610

►

Background: Sleep disorders have been poorly described in children and adolescents diagnosed with FASD. The objective of this study is to describe the sleep and… (more)

Subjects/Keywords: fetal alcohol spectrum disorders (FASD); sleep disorders; circadian rhythms; 0317

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APA (6^th Edition):

Goril, S. (2011). The Patterns of Sleep Disorders and Circadian Rhythm Disruptions in Children and Adolescents with Fetal Alcohol Spectrum Disorders. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/30610

Chicago Manual of Style (16^th Edition):

Goril, Shery. “The Patterns of Sleep Disorders and Circadian Rhythm Disruptions in Children and Adolescents with Fetal Alcohol Spectrum Disorders.” 2011. Masters Thesis, University of Toronto. Accessed January 16, 2021. http://hdl.handle.net/1807/30610.

MLA Handbook (7^th Edition):

Goril, Shery. “The Patterns of Sleep Disorders and Circadian Rhythm Disruptions in Children and Adolescents with Fetal Alcohol Spectrum Disorders.” 2011. Web. 16 Jan 2021.

Vancouver:

Goril S. The Patterns of Sleep Disorders and Circadian Rhythm Disruptions in Children and Adolescents with Fetal Alcohol Spectrum Disorders. [Internet] [Masters thesis]. University of Toronto; 2011. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1807/30610.

Council of Science Editors:

Goril S. The Patterns of Sleep Disorders and Circadian Rhythm Disruptions in Children and Adolescents with Fetal Alcohol Spectrum Disorders. [Masters Thesis]. University of Toronto; 2011. Available from: http://hdl.handle.net/1807/30610

25. Baker, Lesley. The Influence of Mindfulness Training on Social Functioning in Children with Fetal Alcohol Spectrum Disorders.

Degree: Dept. of Psychology, 2013, University of Victoria

URL: http://hdl.handle.net/1828/4903

► It is well documented that children with Fetal Alcohol Spectrum Disorders (FASD) experience difficulties in several domains of social functioning. Despite this evidence, there are… (more)

Subjects/Keywords: FASD; Social Functioning; Mindfulness

…may be diagnosed under the umbrella term Fetal Alcohol Spectrum Disorder (FASD)… …with FASD experience significant behavioural and cognitive challenges in their everyday life… …Research has identified several domains that are commonly affected in individuals with FASD… …also significant. Several longitudinal studies suggest that children with FASD are at greater… …FASD experience significant impairment in a number of social domains including interpersonal…

3 more images…

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APA (6^th Edition):

Baker, L. (2013). The Influence of Mindfulness Training on Social Functioning in Children with Fetal Alcohol Spectrum Disorders. (Masters Thesis). University of Victoria. Retrieved from http://hdl.handle.net/1828/4903

Chicago Manual of Style (16^th Edition):

Baker, Lesley. “The Influence of Mindfulness Training on Social Functioning in Children with Fetal Alcohol Spectrum Disorders.” 2013. Masters Thesis, University of Victoria. Accessed January 16, 2021. http://hdl.handle.net/1828/4903.

MLA Handbook (7^th Edition):

Baker, Lesley. “The Influence of Mindfulness Training on Social Functioning in Children with Fetal Alcohol Spectrum Disorders.” 2013. Web. 16 Jan 2021.

Vancouver:

Baker L. The Influence of Mindfulness Training on Social Functioning in Children with Fetal Alcohol Spectrum Disorders. [Internet] [Masters thesis]. University of Victoria; 2013. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1828/4903.

Council of Science Editors:

Baker L. The Influence of Mindfulness Training on Social Functioning in Children with Fetal Alcohol Spectrum Disorders. [Masters Thesis]. University of Victoria; 2013. Available from: http://hdl.handle.net/1828/4903

University of Delaware

26. Robinson-Drummer, Patrese A. Ontogeny of contextual fear conditioning: behavioral, neuropharmacological and molecular mechanisms.

Degree: PhD, University of Delaware, Department of Psychological and Brain Sciences, 2018, University of Delaware

URL: http://udspace.udel.edu/handle/19716/23586

► This dissertation characterizes learning-related molecular changes in developing rodents using a variant of contextual fear conditioning called the context preexposure facilitation effect (CPFE). The CPFE… (more)

▼ This dissertation characterizes learning-related molecular changes in developing rodents using a variant of contextual fear conditioning called the context preexposure facilitation effect (CPFE). The CPFE is a variant of contextual fear conditioning in which acquisition of the contextual representation (preexposure phase) and association of the retrieved contextual memory with an immediate foot-shock (training phase) are separated by 24 hrs. When tested 24 hr later, animals exhibit significant fear responding to the training context relative to control animals preexposed to an alternate context (Fanselow, 1986, 1990). During the CPFE, expression patterns of the inducible transcription factor early growth response-1 gene (Egr-1) vary based on training phase and brain sub-region in adult and adolescent rats (Asok, Schreiber, Jablonski, Rosen, & Stanton, 2013; Chakraborty, Asok, Stanton, & Rosen, 2016; Schreiber, Asok, Jablonski, Rosen, & Stanton, 2014). Importantly, regions in medial prefrontal cortex (mPFC) show a learning-related increase in Egr-1 expression on the training day, whereby immediate shock increases expression in context-preexposed rats that learn fear, relative to control groups that do not. Behavioral expression of the CPFE emerges between the infant [postnatal day (PD) 17] and juvenile (PD 24) period in the rat (Schiffino et al., 2012; Robinson-Drummer & Stanton, 2015), but it is not known whether Egr-1 expression correlates with this effect. Experiment 1 of this dissertation addressed this question by examining behavior and Egr-1 expression in infant (PD 17) and juvenile (PD 24) rats during the CPFE using preexposure protocols involving a single-exposure or multiple-exposures to the training context. Following a single, 5 min preexposure to the training context, Egr-1 expression in the mPFC, dorsal hippocampus (dHPC) and lateral nucleus of the amygdala (LA) was increased in PD 24 rats but not PD 17 rats. In contrast, increased Egr-1 expression following an immediate foot-shock (1 s, 1.5 mA) did not differ between PD 17 and PD 24 rats, and was not learning-related. Interestingly, increasing the number of exposures to the training chamber on the preexposure day (i.e. multiple-exposure protocol) altered training-day expression such that a learning-related increase in expression was observed in the mPFC in PD 31 and 24 but not PD 17 rats. However, across all experiments, behavioral expression of the CPFE was related to age-differences in Egr-1 expression on the preexposure day but not the training day. ☐ The second experiment in this dissertation used a rodent model of fetal alcohol spectrum disorder (FASD) to examine the effect of neonatal alcohol exposure on Egr-1 mRNA expression following the training day of the CPFE. Prenatal alcohol exposure in humans can adversely affect postnatal cognitive, behavioral and neural development (Del Campo & Jones, 2017; Senturias & Asamoah, 2014). Extensive human and animal research on FASD has been invaluable in elucidating the neurobiological substrates of the… Advisors/Committee Members: Stanton, Mark E..

Subjects/Keywords: Biological sciences; Context fear; CPFE; FASD; Learning; Ontogeny

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APA (6^th Edition):

Robinson-Drummer, P. A. (2018). Ontogeny of contextual fear conditioning: behavioral, neuropharmacological and molecular mechanisms. (Doctoral Dissertation). University of Delaware. Retrieved from http://udspace.udel.edu/handle/19716/23586

Chicago Manual of Style (16^th Edition):

Robinson-Drummer, Patrese A. “Ontogeny of contextual fear conditioning: behavioral, neuropharmacological and molecular mechanisms.” 2018. Doctoral Dissertation, University of Delaware. Accessed January 16, 2021. http://udspace.udel.edu/handle/19716/23586.

MLA Handbook (7^th Edition):

Robinson-Drummer, Patrese A. “Ontogeny of contextual fear conditioning: behavioral, neuropharmacological and molecular mechanisms.” 2018. Web. 16 Jan 2021.

Vancouver:

Robinson-Drummer PA. Ontogeny of contextual fear conditioning: behavioral, neuropharmacological and molecular mechanisms. [Internet] [Doctoral dissertation]. University of Delaware; 2018. [cited 2021 Jan 16]. Available from: http://udspace.udel.edu/handle/19716/23586.

Council of Science Editors:

Robinson-Drummer PA. Ontogeny of contextual fear conditioning: behavioral, neuropharmacological and molecular mechanisms. [Doctoral Dissertation]. University of Delaware; 2018. Available from: http://udspace.udel.edu/handle/19716/23586

University of Otago

27. Smith, Caine Christopher. Temporal Changes in the Expression of BAX and BCL-2, and the Sub-regional Vulnerability to Cellular Apoptosis after a Binge-like Ethanol Exposure in the Developing Rattus norvegicus Hippocampus .

Degree: 2013, University of Otago

URL: http://hdl.handle.net/10523/4415

► Exposure to ethanol in utero can result in life-long disability. Ethanol is neurotoxic, and exposure of high doses during development results in widespread cell death.… (more)

Subjects/Keywords: Alcohol; FAS; FASD; Ethanol; Binge-drink; Apoptosis; Hippocampus

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APA (6^th Edition):

Smith, C. C. (2013). Temporal Changes in the Expression of BAX and BCL-2, and the Sub-regional Vulnerability to Cellular Apoptosis after a Binge-like Ethanol Exposure in the Developing Rattus norvegicus Hippocampus . (Masters Thesis). University of Otago. Retrieved from http://hdl.handle.net/10523/4415

Chicago Manual of Style (16^th Edition):

Smith, Caine Christopher. “Temporal Changes in the Expression of BAX and BCL-2, and the Sub-regional Vulnerability to Cellular Apoptosis after a Binge-like Ethanol Exposure in the Developing Rattus norvegicus Hippocampus .” 2013. Masters Thesis, University of Otago. Accessed January 16, 2021. http://hdl.handle.net/10523/4415.

MLA Handbook (7^th Edition):

Smith, Caine Christopher. “Temporal Changes in the Expression of BAX and BCL-2, and the Sub-regional Vulnerability to Cellular Apoptosis after a Binge-like Ethanol Exposure in the Developing Rattus norvegicus Hippocampus .” 2013. Web. 16 Jan 2021.

Vancouver:

Smith CC. Temporal Changes in the Expression of BAX and BCL-2, and the Sub-regional Vulnerability to Cellular Apoptosis after a Binge-like Ethanol Exposure in the Developing Rattus norvegicus Hippocampus . [Internet] [Masters thesis]. University of Otago; 2013. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/10523/4415.

Council of Science Editors:

Smith CC. Temporal Changes in the Expression of BAX and BCL-2, and the Sub-regional Vulnerability to Cellular Apoptosis after a Binge-like Ethanol Exposure in the Developing Rattus norvegicus Hippocampus . [Masters Thesis]. University of Otago; 2013. Available from: http://hdl.handle.net/10523/4415

University of Manitoba

28. Amiri, Shayan. Investigating the effect of continuous ethanol exposure on differentiated neural stem cells; a study for potential FASD biomarkers.

Degree: Biochemistry and Medical Genetics, 2019, University of Manitoba

URL: http://hdl.handle.net/1993/33621

► Prenatal alcohol exposure (PAE) is considered as a risk factor for the development of fetal alcohol spectrum disorders (FASD). Mounting evidence suggests that PAE affects… (more)

▼ Prenatal alcohol exposure (PAE) is considered as a risk factor for the development of fetal alcohol spectrum disorders (FASD). Mounting evidence suggests that PAE affects epigenetic mechanisms and alters the normal differentiation and development of neural stem cells (NSC) in fetal brain. DNA methylation, as an important epigenetic mechanism, contributes to several biological processes during brain development and undergoes significant changes following PAE. In addition, recent studies suggest that DNA methylation is a considerable biomarker for the early diagnosis of FASD. However, effects of PAE are dependent to a variety of factors such as sex and strain of studied subjects. In this regard, we aimed to investigate whether sex and strain play a determinant role in the effects of chronic ethanol exposure on DNA methylation machinery. In addition, based on our previously studied RNA-Sequencing data, we tested the validity of three potential biomarkers (Dcc, Scn3a, and Sptbn2), which were suggested by IPA (Ingenuity Pathway Analysis) software. To do this, we applied a standard and controlled in vitro model system, in which we treated male and female differentiating NSC (obtained from the forebrain of CD1 and BL6 embryos at the embryonic day 14.5) with chronic ethanol exposure (70 mM) for 8 days. Our results showed that chronic ethanol treatment induced global DNA hypomethylation and altered the components of DNA methylation machinery in a sex and strain-specific manner. These alterations in DNA methylation status were associated with altered expression of glial markers CNPASE, GFAP, and OLIG2 in CD1 (but not BL6) cells. We also found that Dcc, Scn3a, and Sptbn2 and their corresponding proteins were altered by ethanol exposure, but may not be true candidate biomarkers for FASD biomarkers because their alterations were not consistent in all experimental groups. In conclusion, the effects of ethanol on DNA methylation of differentiated NSC depended on sex and strain of cells, and DNA methylation alone may not be a suitable biomarker for FASD without consideration of sex and strain. In addition, the effects of ethanol on NCS fate commitment were only observed in CD1 cells and not BL6 cells. Taken together, the results of this work provided evidence that chronic ethanol exposure affects DNA methylation and cell fate commitment in differentiated NSC, but in a sex and strain-specific manner. My results also revealed that either DNA methylation and/or candidate biomarkers (Dcc, Scn3a, and Sptbn2) alone may not be suitable biomarkers for FASD. Advisors/Committee Members: Rastegar, Mojgan (Biochemistry and Medical Genetics) (supervisor), Siddiqui, Tabrez (Physiology and Pathophysiology).

Subjects/Keywords: FASD; DNA methylation; Neural stem cells; Biomarkers; Ethanol; Differentiation

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APA (6^th Edition):

Amiri, S. (2019). Investigating the effect of continuous ethanol exposure on differentiated neural stem cells; a study for potential FASD biomarkers. (Masters Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/33621

Chicago Manual of Style (16^th Edition):

Amiri, Shayan. “Investigating the effect of continuous ethanol exposure on differentiated neural stem cells; a study for potential FASD biomarkers.” 2019. Masters Thesis, University of Manitoba. Accessed January 16, 2021. http://hdl.handle.net/1993/33621.

MLA Handbook (7^th Edition):

Amiri, Shayan. “Investigating the effect of continuous ethanol exposure on differentiated neural stem cells; a study for potential FASD biomarkers.” 2019. Web. 16 Jan 2021.

Vancouver:

Amiri S. Investigating the effect of continuous ethanol exposure on differentiated neural stem cells; a study for potential FASD biomarkers. [Internet] [Masters thesis]. University of Manitoba; 2019. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1993/33621.

Council of Science Editors:

Amiri S. Investigating the effect of continuous ethanol exposure on differentiated neural stem cells; a study for potential FASD biomarkers. [Masters Thesis]. University of Manitoba; 2019. Available from: http://hdl.handle.net/1993/33621

University of Manitoba

29. Batuwita Liyanage, Vichithra Rasangi. Intrinsic and extrinsic regulation of MeCP2 in brain cell types and their implications in MeCP2-related neurodevelopmental disorders.

Degree: Biochemistry and Medical Genetics, 2013, University of Manitoba

URL: http://hdl.handle.net/1993/32732

► MeCP2 is a key epigenetic regulator in the brain, which regulates gene expression. There are two Mecp2/MeCP2 isoforms - MeCP2E1 and MeCP2E2 - with both… (more)

▼ MeCP2 is a key epigenetic regulator in the brain, which regulates gene expression. There are two Mecp2/MeCP2 isoforms - MeCP2E1 and MeCP2E2 - with both overlapping and non-overlapping expression and functions in the brain. MeCP2 is widely expressed in different brain cell types but predominantly expressed in neurons. MECP2/MeCP2-deficiency and overexpression are associated with Rett Syndrome (RTT), MECP2 duplication syndrome (MDS) and alcohol (ethanol)-mediated neurological damage, such as Fetal Alcohol Spectrum Disorders (FASD). These disorders have no cure. Rescuing the expression levels of MeCP2 could be a potential therapeutic approach for these diseases. A thorough understanding of MeCP2 expression regulation is essential to achieve this goal. The objective of my Ph.D. project presented in this thesis is to address the knowledge gap on Mecp2 regulation in the brain, which has been carried out using cellular models of in vitro neural stem cell (NSC) differentiation and in vivo differentiated neurons and astrocytes. As such, the intrinsic regulation of Mecp2 isoforms by epigenetic and transcriptional mechanisms, and extrinsic regulation of Mecp2 isoforms by the insult of ethanol exposure were explored in this thesis. We identified six regulatory elements (REs) within the Mecp2 promoter and intron 1, DNA methylation of which correlated with the expression of Mecp2 isoforms during NSC differentiation [Liyanage et al. (2013), Molecular Autism]. The role of DNA methylation in Mecp2 regulation was studied by treatment with a DNA demethylating agent decitabine, which was identified as a potential drug that induces Mecp2/MeCP2 expression in an isoform-specific manner. In terms of the extrinsic regulation by ethanol, dynamic DNA methylation patterns at these REs was associated with the alterations of Mecp2 levels by ethanol exposure and withdrawal during NSC differentiation [Liyanage et al. (2015), Experimental Neurology]. We also found that expression of Mecp2 isoforms in primary neurons and astrocytes is cell type- and sex-specific. The higher expression of Mecp2 isoforms in neurons as compared to astrocytes is possibly mediated through lower DNA methylation levels in these identified REs. Taken together, my studies provide evidence for the role of DNA methylation in epigenetic regulation of Mecp2 in these brain cells, under normal conditions and in response to extrinsic deregulation by ethanol exposure. The ability of the DNA methylation inhibitor decitabine to upregulate Mecp2 levels provides insights on potential future drug treatment strategies for MeCP2-deficiency-associated neurological conditions. The knowledge gained from this study will hold promise for utilizing these intrinsic and extrinsic regulatory mechanisms of Mecp2 isoforms for a better understanding of diseases pathology and provides insights into translational knowledge on further MeCP2 research and therapy strategies for MeCP2-associated neurological disorders. Advisors/Committee Members: Rastegar, Mojgan (Biochemistry and Medical Genetics) (supervisor), Davie, James (Biochemistry and Medical Genetics).

Subjects/Keywords: MeCP2; DNA methylation; Epigenetics; FASD; Rett syndrome; Autism; MeCP2 isoforms; Alcohol

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Batuwita Liyanage, V. R. (2013). Intrinsic and extrinsic regulation of MeCP2 in brain cell types and their implications in MeCP2-related neurodevelopmental disorders. (Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/32732

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Batuwita Liyanage, Vichithra Rasangi. “Intrinsic and extrinsic regulation of MeCP2 in brain cell types and their implications in MeCP2-related neurodevelopmental disorders.” 2013. Thesis, University of Manitoba. Accessed January 16, 2021. http://hdl.handle.net/1993/32732.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Batuwita Liyanage, Vichithra Rasangi. “Intrinsic and extrinsic regulation of MeCP2 in brain cell types and their implications in MeCP2-related neurodevelopmental disorders.” 2013. Web. 16 Jan 2021.

Vancouver:

Batuwita Liyanage VR. Intrinsic and extrinsic regulation of MeCP2 in brain cell types and their implications in MeCP2-related neurodevelopmental disorders. [Internet] [Thesis]. University of Manitoba; 2013. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1993/32732.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Batuwita Liyanage VR. Intrinsic and extrinsic regulation of MeCP2 in brain cell types and their implications in MeCP2-related neurodevelopmental disorders. [Thesis]. University of Manitoba; 2013. Available from: http://hdl.handle.net/1993/32732

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

30. Chatterley-Gonzalez, Allison. The experiences and needs of young people with FASD: silenced voices from youth in care.

Degree: Social Work, 2010, University of Manitoba

URL: http://hdl.handle.net/1993/3927

► This research explores the experiences and needs of five young people with FASD in care. Data was gathered through personal interviews with youth in care,… (more)

Subjects/Keywords: youth in care; FASD

…preventing, intervening and managing Fetal Alcohol Spectrum Disorders (FASD). FASD is a… …Adolescents affected by FASD are a special group of youth that often find themselves in care… …each individual person with FASD. I have noticed that young people with this disability… …adolescents with FASD tend to be labeled as a ‘behavior problem’, their difficult behaviors… …coined the term NURMU to describe how young people with FASD are often viewed by caregivers and…

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Chatterley-Gonzalez, A. (2010). The experiences and needs of young people with FASD: silenced voices from youth in care. (Masters Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/3927

Chicago Manual of Style (16^th Edition):

Chatterley-Gonzalez, Allison. “The experiences and needs of young people with FASD: silenced voices from youth in care.” 2010. Masters Thesis, University of Manitoba. Accessed January 16, 2021. http://hdl.handle.net/1993/3927.

MLA Handbook (7^th Edition):

Chatterley-Gonzalez, Allison. “The experiences and needs of young people with FASD: silenced voices from youth in care.” 2010. Web. 16 Jan 2021.

Vancouver:

Chatterley-Gonzalez A. The experiences and needs of young people with FASD: silenced voices from youth in care. [Internet] [Masters thesis]. University of Manitoba; 2010. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/1993/3927.

Council of Science Editors:

Chatterley-Gonzalez A. The experiences and needs of young people with FASD: silenced voices from youth in care. [Masters Thesis]. University of Manitoba; 2010. Available from: http://hdl.handle.net/1993/3927

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Open Access Theses and Dissertations