subject:(Experimental challenge)

University of Georgia

1. Jackson, Kayla. Development of a challenge model to experimentally induce Streptococcus uberis mastitis in bred dairy heifers.

Degree: 2014, University of Georgia

URL: http://hdl.handle.net/10724/27486

► A reproducible challenge model for inducing Streptococcus uberis mastitis in dairy heifers was developed. Heifers were assigned 2 quarters to receive an infusion of Strep.… (more)

Subjects/Keywords: Experimental challenge; dairy heifers; mastitis; Streptococcus uberis

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APA (6^th Edition):

Jackson, K. (2014). Development of a challenge model to experimentally induce Streptococcus uberis mastitis in bred dairy heifers. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/27486

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Jackson, Kayla. “Development of a challenge model to experimentally induce Streptococcus uberis mastitis in bred dairy heifers.” 2014. Thesis, University of Georgia. Accessed April 17, 2021. http://hdl.handle.net/10724/27486.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Jackson, Kayla. “Development of a challenge model to experimentally induce Streptococcus uberis mastitis in bred dairy heifers.” 2014. Web. 17 Apr 2021.

Vancouver:

Jackson K. Development of a challenge model to experimentally induce Streptococcus uberis mastitis in bred dairy heifers. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Apr 17]. Available from: http://hdl.handle.net/10724/27486.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Jackson K. Development of a challenge model to experimentally induce Streptococcus uberis mastitis in bred dairy heifers. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/27486

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

North Carolina State University

2. Tillman, Warren Scott. The Development of a Streptoccocus uberis mastitis Challenge Protocol.

Degree: MS, Animal Science, 2007, North Carolina State University

URL: http://www.lib.ncsu.edu/resolver/1840.16/353

► A series of experiments was conducted using a S. uberis bacterial isolate in order to produce a predictable and effective protocol for experimental induction of… (more)

▼ A series of experiments was conducted using a S. uberis bacterial isolate in order to produce a predictable and effective protocol for experimental induction of mastitis. A bacterial isolate was obtained from a clinical mastitis infection in a local, North Carolina dairy herd. In vitro growth of the bacterial isolate produced a predicted lag, log, stationary, and death phase. Comparison of optical absorbance values to bacterial concentrations resulted in a Pearson's correlation coefficient of 0.71. It was determined that time of growth would be a better indicator of bacterial concentration. S. uberis isolates were incubated for 3 hours of growth and placed on ice to observe temporal changes in bacterial concentration. Bacterial concentration did not differ over time (P=0.96), indicating that ice storage maintained S. uberis concentrations for 3 hours. S. uberis bacterial concentrations deviated from predicted values in growth curves, so an alteration to the serial dilution protocol was performed in order to reach the desired concentration. Four Holstein cows were challenged with 5, 400 cfu of S. uberis in 2 quarters that contained no mastitis pathogens and were compared to 4 Holstein control cows. The inoculum concentration produced a 100% incidence of clinical infection in all quarters challenged. The challenged group exhibited elevated quarter milk scores, quarter pain scores, attitude scores, and quarter size scores, with first clinical signs occurring at 36 hours. Rectal temperatures were highest at 36 hours (40.5 ± .3 o C vs. 38.5 ± .3 o C; P<0 .0001) (mean ± SEM) compared to control. Challenged quarter somatic cell counts (SCC) were elevated at 24 hours post-infusion in comparison to control quarter SCC at 0 (Challenge 24: 3.5 X 106 ± 5.6 X 106 vs. Control 0: 4.3 X 104 ± 3.1 X 104; P < 0.0001) and 24 hours (Challenge 24: 3.5 X 106 ± 5.6 X 106 vs. Control 24: 6.7 X 104 ± 5.0 X 104; P = 0.003). Challenge quarter SCC at 24 hours also differed from challenge SCC values at time of challenge (Challenge 24: 3.5 X 106 ± 5.6 X 106 vs. Challenge 0: 1.4 X 105 ± 2.1 X 105; P < 0.0001). While a predictable mastitis model was acquired using 5,400 cfu, the response in challenged cows was more severe than preferred. In the attempt to obtain a clinical infection that was physiologically more benign (low-grade pyrexia, less severe quarter abnormalities, and faster response to treatment), it was determined that lower doses might still produce a high incidence of clinical infection while presenting less severe clinical signs. In this trial, 500 cfu (low dose; n=6 quarters in 3 cows), 1,950 cfu (medium dose; n=5 quarters in 3 cows), and 4,000 cfu (high dose; n=6 quarters in 3 cows) were inoculated into quarters that contained no intramammary pathogens. All cows (n=9) and 13⁄17 (76.5%) quarters developed a clinical infection. Regardless of dose, an overall elevation in SCC from baseline values was reported following challenge (P < 0.0001). … Advisors/Committee Members: Peter Farin, Committee Member (advisor), Kevin Anderson, Committee Member (advisor), Mitchell Hockett, Committee Chair (advisor), Scott Whisnant, Committee Member (advisor).

Subjects/Keywords: mastitis; uberis; Streptococcus; experimental challenge

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APA (6^th Edition):

Tillman, W. S. (2007). The Development of a Streptoccocus uberis mastitis Challenge Protocol. (Thesis). North Carolina State University. Retrieved from http://www.lib.ncsu.edu/resolver/1840.16/353

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Tillman, Warren Scott. “The Development of a Streptoccocus uberis mastitis Challenge Protocol.” 2007. Thesis, North Carolina State University. Accessed April 17, 2021. http://www.lib.ncsu.edu/resolver/1840.16/353.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Tillman, Warren Scott. “The Development of a Streptoccocus uberis mastitis Challenge Protocol.” 2007. Web. 17 Apr 2021.

Vancouver:

Tillman WS. The Development of a Streptoccocus uberis mastitis Challenge Protocol. [Internet] [Thesis]. North Carolina State University; 2007. [cited 2021 Apr 17]. Available from: http://www.lib.ncsu.edu/resolver/1840.16/353.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Tillman WS. The Development of a Streptoccocus uberis mastitis Challenge Protocol. [Thesis]. North Carolina State University; 2007. Available from: http://www.lib.ncsu.edu/resolver/1840.16/353

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

3. Diana Suckeveris. Estudo sobre a utilização de níveis supranutricionais de vitaminas hidrossolúveis na produção de frangos de corte.

Degree: 2019, University of São Paulo

URL: http://www.teses.usp.br/teses/disponiveis/11/11139/tde-02082019-160117/

► A exigência em vitaminas do complexo B pode modificar para frangos de corte criados sob condições comerciais (i.e. condições de estresse, presença de doenças, ambiente… (more)

▼ A exigência em vitaminas do complexo B pode modificar para frangos de corte criados sob condições comerciais (i.e. condições de estresse, presença de doenças, ambiente desfavorável). Esse incremento nos níveis de suplementação vitamínica pode ser necessário para que as aves atinjam elevadas taxas de crescimento, melhorem o aproveitamento dos alimentos e a saúde animal. No presente estudo foram realizados três experimentos com o objetivo de avaliar níveis supranutricionais de suplementação das vitaminas riboflavina, ácido pantotênico, niacina, ácido fólico e vitamina B12 na produção de frangos de corte. Para isto, dois experimentos foram conduzidos em gaiolas para avaliar o efeito dos níveis das vitaminas riboflavina, ácido pantotênico, niacina, ácido fólico e vitamina B12 (controle, três ou seis vezes o controle) e o nível nutricional e energético (regular ou superior) que promoveram as melhores respostas para frangos de corte, sendo no experimento I utilizada dieta vegetal e no experimento II foram incluídas farinhas de origem animal e óleo de soja oxidados na ração. Frangos alimentados com dieta vegetal formulada com densidade nutricional regular apresentaram respostas positivas de ganho de peso (741,1 g vs. 697,3 g) e consumo de ração (920.2 vs. 878.5 g) em relação aos demais tratamentos quando utilizado nível supranutricional seis vezes o controle das vitaminas avaliadas. Por outro lado, os níveis supranutricionais de vitaminas não apresentaram efeitos no desempenho de animais alimentados com ingredientes origem animal e óleo de soja oxidados. Com base nas respostas obtidas nestes experimentos, foram definidos os tratamentos do estudo em aviário experimental, simulando condições comerciais de criação. Utilizou-se dieta vegetal formulada com nível nutricional e energético regular para avaliar o uso de nível de suplementação vitamínica controle e seis vezes o controle em duas condições de estresse, baixa e moderada. Para compor estas condições de estresse foi considerada a combinação de dois fatores: densidade de alojamento (10 aves/m2 ou 11,5 aves/m2) e desafio com vacina contra coccidiose. Aos sete dias de idade, aves sob condição moderada de estresse foram desafiadas com uma dosagem 10 vezes em relação ao recomendado pelo fornecedor de uma vacina contra coccidiose. Após o desafio com a vacina, aves sob moderada condição de estresse apresentaram decréscimo no desempenho em relação as criadas sob baixa condição de estresse. Não houve efeito estatístico do uso de nível supranutricional de vitaminas sobre o desempenho das aves. No entanto, aves alimentadas com superdose de vitaminas seis vezes o controle obtiveram maior rendimento de carcaça em comparação às alimentadas com nível controle (73.16 vs. 72.77%, P = 0.008). Devido ao fato das condições de estresse impostas neste estudo não serem severas como as encontradas no campo, a utilização de nível supranutricional de vitaminas não foi eficiente em recuperar o desempenho das aves. Por outro lado, há um potencial de melhora no rendimento de carcaça com o uso desses… Advisors/Committee Members: José Fernando Machado Menten, Jose Eurico Possebon Cyrino, Daniel Emygdio de Faria Filho, Rafael Gustavo Hermes.

Subjects/Keywords: Desafio experimental; Dieta vegetal; Superdose; Vitaminas do complexo B; B-vitamin complex; Experimental challenge; Super-dose; Vegetable diet

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APA (6^th Edition):

Suckeveris, D. (2019). Estudo sobre a utilização de níveis supranutricionais de vitaminas hidrossolúveis na produção de frangos de corte. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/11/11139/tde-02082019-160117/

Chicago Manual of Style (16^th Edition):

Suckeveris, Diana. “Estudo sobre a utilização de níveis supranutricionais de vitaminas hidrossolúveis na produção de frangos de corte.” 2019. Doctoral Dissertation, University of São Paulo. Accessed April 17, 2021. http://www.teses.usp.br/teses/disponiveis/11/11139/tde-02082019-160117/.

MLA Handbook (7^th Edition):

Suckeveris, Diana. “Estudo sobre a utilização de níveis supranutricionais de vitaminas hidrossolúveis na produção de frangos de corte.” 2019. Web. 17 Apr 2021.

Vancouver:

Suckeveris D. Estudo sobre a utilização de níveis supranutricionais de vitaminas hidrossolúveis na produção de frangos de corte. [Internet] [Doctoral dissertation]. University of São Paulo; 2019. [cited 2021 Apr 17]. Available from: http://www.teses.usp.br/teses/disponiveis/11/11139/tde-02082019-160117/.

Council of Science Editors:

Suckeveris D. Estudo sobre a utilização de níveis supranutricionais de vitaminas hidrossolúveis na produção de frangos de corte. [Doctoral Dissertation]. University of São Paulo; 2019. Available from: http://www.teses.usp.br/teses/disponiveis/11/11139/tde-02082019-160117/

4. Cornick, Jessica. Physiological Responses to Perceived Exergame Task Demands.

Degree: 2016, University of California – eScholarship, University of California

URL: http://www.escholarship.org/uc/item/78v8s42d

► Exercise videogames are increasingly popular as individuals seek to increase daily exercise. This study assessed physiological reactions to perceived task demands from a virtual exercise… (more)

Subjects/Keywords: Social psychology; Experimental psychology; Health sciences; Biopsychosocial model of challenge and threat; Exercise; Exergame; Self-efficacy

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APA (6^th Edition):

Cornick, J. (2016). Physiological Responses to Perceived Exergame Task Demands. (Thesis). University of California – eScholarship, University of California. Retrieved from http://www.escholarship.org/uc/item/78v8s42d

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Cornick, Jessica. “Physiological Responses to Perceived Exergame Task Demands.” 2016. Thesis, University of California – eScholarship, University of California. Accessed April 17, 2021. http://www.escholarship.org/uc/item/78v8s42d.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Cornick, Jessica. “Physiological Responses to Perceived Exergame Task Demands.” 2016. Web. 17 Apr 2021.

Vancouver:

Cornick J. Physiological Responses to Perceived Exergame Task Demands. [Internet] [Thesis]. University of California – eScholarship, University of California; 2016. [cited 2021 Apr 17]. Available from: http://www.escholarship.org/uc/item/78v8s42d.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Cornick J. Physiological Responses to Perceived Exergame Task Demands. [Thesis]. University of California – eScholarship, University of California; 2016. Available from: http://www.escholarship.org/uc/item/78v8s42d

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Gothenburg / Göteborgs Universitet

5. Arvidsson, Monica B., 1955-. Effect of allergen specific immunotherapy on allergic inflammation in the upper and lower airways.

Degree: 2003, University of Gothenburg / Göteborgs Universitet

URL: http://hdl.handle.net/2077/16077

► Experimental allergen challenge is widely used in diagnostic practice and research in allergy, but its relationship to environmental exposures is not clarified. Both models of… (more)

▼ Experimental allergen challenge is widely used in diagnostic practice and research in allergy, but its relationship to environmental exposures is not clarified. Both models of allergic diseases have been used in order to examine the effects of allergen specific immunotherapy (SIT). Placebo-controlled studies have demonstrated the clinical efficacy of this treatment. However, long-term placebo-controlled studies with standardized birch pollen extract were lacking and the effect on early and late asthmatic reactions had not been examined in birch pollen-allergic patients. The aims of this thesis were (I) to investigate the relationship between experimental and environmental bronchial challenge; (II) to examine the early kinetics of skin and mucosal sensitivity following rush immunotherapy (rapid up-dosing schedule); (III) to evaluate the effect of immunotherapy with standardized birch pollen extract on airway symptoms and use of medication in birch pollen-allergic patients in a placebo-controlled study and; (IV) to examine the effect of specific immunotherapy with standardized birch pollen extract on early- and late-phase asthmatic reactions in asthmatic patients. Sixty-two patients with cat-induced asthma underwent an experimental allergen bronchial challenge followed by an environmental challenge. Thirty-four percent (21/62) of the patients developed a late response in both challenge models and 31% (19/62) failed to develop a late response in either model. Thus, consistency in development of a late response was found in 65% of the patients. Twelve cat- and five birch pollen-allergic patients received rush immunotherapy and underwent allergen challenges to skin and conjunctiva plus methacholine tests of lower airways and blood cell counts before and after 3 days, 1 week, 3 weeks and 12 weeks of therapy. Treatment significantly reduced skin and conjunctival sensitivity after three weeks, while transient increases in eosinophil numbers and bronchial hyperreactivity were seen after one week. In a 2-year placebo-controlled immunotherapy 49 patients with a history of birch pollen allergy symptoms involving the upper and lower airways were included and treated with a standardized birch pollen extract. A significant reduction in symptoms and use of medication was demonstrated in the treatment group compared to the placebo. In a further placebo-controlled study including 19 birch pollen asthmatic patients, a significant decrease in early and late asthmatic responses was seen following allergen bronchial challenge after one year of birch SIT.In conclusion: The results show that environmental bronchial challenges may be replaced by experimental challenges for studies of the late phase reaction in allergic asthma. Rush immunotherapy was found to significantly reduce the skin and conjunctival sensitivity while transient increases in eosinophil numbers and bronchial hyperreactivity were seen. Allergen specific immunotherapy with birch pollen extract was shown to be a clinical effective and safe treatment. An attenuation of…

Subjects/Keywords: birch pollen allergy; cat allergy; specific immunotherapy; rush immunotherapy; experimental allergen challenge; environmental allergen challenge; late asthmatic response

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APA (6^th Edition):

Arvidsson, Monica B., 1. (2003). Effect of allergen specific immunotherapy on allergic inflammation in the upper and lower airways. (Thesis). University of Gothenburg / Göteborgs Universitet. Retrieved from http://hdl.handle.net/2077/16077

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Arvidsson, Monica B., 1955-. “Effect of allergen specific immunotherapy on allergic inflammation in the upper and lower airways.” 2003. Thesis, University of Gothenburg / Göteborgs Universitet. Accessed April 17, 2021. http://hdl.handle.net/2077/16077.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Arvidsson, Monica B., 1955-. “Effect of allergen specific immunotherapy on allergic inflammation in the upper and lower airways.” 2003. Web. 17 Apr 2021.

Vancouver:

Arvidsson, Monica B. 1. Effect of allergen specific immunotherapy on allergic inflammation in the upper and lower airways. [Internet] [Thesis]. University of Gothenburg / Göteborgs Universitet; 2003. [cited 2021 Apr 17]. Available from: http://hdl.handle.net/2077/16077.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Arvidsson, Monica B. 1. Effect of allergen specific immunotherapy on allergic inflammation in the upper and lower airways. [Thesis]. University of Gothenburg / Göteborgs Universitet; 2003. Available from: http://hdl.handle.net/2077/16077

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Swedish University of Agricultural Sciences

6. Jansson, Désirée. Genus brachyspira in birds.

Degree: 2009, Swedish University of Agricultural Sciences

URL: http://pub.epsilon.slu.se/1943/

► Spirochaetes of genus Brachyspira colonize the large intestine of some mammals and birds, and cause intestinal disease and production losses in pigs and chickens. The… (more)

▼ Spirochaetes of genus Brachyspira colonize the large intestine of some mammals and birds, and cause intestinal disease and production losses in pigs and chickens. The precise significance of Brachyspira spp. colonization in birds, the bacterial species involved, and the epidemiology are incompletely understood. Possible transmission between birds and mammals, and the role of wildlife have previously received little attention. In this thesis intestinal spirochaetes were isolated from commercial laying hens and free-living wild mallards (Anas platyrhynchos), jackdaws (Corvus monedula), rooks (C. frugilegus) and hooded crows (C. corone cornix). The isolates were investigated by phenotypic tests, molecular methods (PCR, RAPD, PFGE, sequencing of 16S rRNA and nox genes) and phylogenetic analysis. Experimental animal models were applied in pigs and mallards to study colonization rates and enteropathogenicity. The results showed that Brachyspira spp. were commonly isolated from the investigated species. Phenotypic and molecular analyses showed considerable diversity, and simultaneous colonization by two or more species or genetic variants of the same species was commonly found. In laying hens, pathogenic species (B. intermedia and B. alvinipulli), presumed non-pathogenic species (B. innocens, murdochii, ‘B. pulli’), and isolates that could not be assigned to any presently known species were isolated. No association with disease or production losses was identified. The etiologic agent of swine dysentery, B. hyodysenteriae, was isolated from mallards, which is the first time from wild birds. A putative novel species, ‘B. suanatina’, was isolated from mallards and Swedish and Danish pig herds. Isolates from both a pig and a mallard were shown to cause diarrhoea in pigs by experimental challenge. In mallards, focal epithelial changes were observed with B. hyodysenteriae and ‘B. suanatina’. Another novel and presumed non-pathogenic species, ‘B. corvi’, from corvid birds, was characterized and provisionally described. The results of the thesis highlight the diagnostic difficulties, the genetic diversity, and suggest that birds may be important reservoirs of Brachyspira spp.

Subjects/Keywords: birds; swine; crows; layer chickens; spirochaetales; phenotypes; phylogeny; swine dysentery; intestinal diseases; epidemiology; Anas; Brachyspira; Corvus; experimental challenge; laying hen; phenotype; phylogeny; molecular characterization; spirochaete; swine dysentery

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Jansson, D. (2009). Genus brachyspira in birds. (Doctoral Dissertation). Swedish University of Agricultural Sciences. Retrieved from http://pub.epsilon.slu.se/1943/

Chicago Manual of Style (16^th Edition):

Jansson, Désirée. “Genus brachyspira in birds.” 2009. Doctoral Dissertation, Swedish University of Agricultural Sciences. Accessed April 17, 2021. http://pub.epsilon.slu.se/1943/.

MLA Handbook (7^th Edition):

Jansson, Désirée. “Genus brachyspira in birds.” 2009. Web. 17 Apr 2021.

Vancouver:

Jansson D. Genus brachyspira in birds. [Internet] [Doctoral dissertation]. Swedish University of Agricultural Sciences; 2009. [cited 2021 Apr 17]. Available from: http://pub.epsilon.slu.se/1943/.

Council of Science Editors:

Jansson D. Genus brachyspira in birds. [Doctoral Dissertation]. Swedish University of Agricultural Sciences; 2009. Available from: http://pub.epsilon.slu.se/1943/

Royal Holloway, University of London

7. Mappley, Luke John. Understanding the pathobiology of Brachyspira pilosicoli in order to develop novel intervention strategies against avian intestinal spirochaetosis.

Degree: PhD, 2012, Royal Holloway, University of London

URL: https://pure.royalholloway.ac.uk/portal/en/publications/understanding-the-pathobiology-of-brachyspira-pilosicoli-in-order-to-develop-novel-intervention-strategies-against-avian-intestinal-spirochaetosis(c71a3915-d765-4aa0-9932-b75434b4cd68).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.580621

► The anaerobic spirochaete Brachyspira pilosicoli causes enteric disease in avian, porcine and human hosts, amongst others. Avian intestinal spirochaetosis (AIS), the resulting disease from colonisation… (more)

▼ The anaerobic spirochaete Brachyspira pilosicoli causes enteric disease in avian, porcine and human hosts, amongst others. Avian intestinal spirochaetosis (AIS), the resulting disease from colonisation of the caeca and colon of poultry by Brachyspira leads to production losses, with an estimated annual cost of circa £18 million to the commercial layer industry in the United Kingdom. A lack of knowledge of the metabolic capabilities and little genomic information for Brachyspira has resulted in a limited understanding of the pathobiology of this genus. In addition, an emergence of antibiotic resistance in Brachyspira, together with bans on the prophylactic use of antimicrobials in animal feed, drive an urgent requirement for alternative treatment strategies for diseases such as AIS. In the first intra-species genome comparison within the genus Brachyspira, these studies report the whole genome sequence of an avian strain of B. pilosicoli, B2904, and the incomplete genome sequence of a human strain of B. pilosicoli, WesB. Comparisons are made between the de novo sequenced strains and those of B. pilosicoli 95/1000, a pig strain and other available Brachyspira genome sequences from public databases. Furthermore, this study reports the first application of the high-throughput Biolog phenotype screening tool to Brachyspira for detailed phenotypic analysis and confirmation of metabolic deductions made from the genotypic data. Probiotics have been reported as protecting against infection with common enteric pathogens in livestock and in this study investigations into which aspects of the biology of Brachyspira they antagonise were undertaken. Lactobacilli reduced the growth and motility of B. pilosicoli and its ability to adhere and invade epithelial cells in vitro. Following these encouraging results, an in vivo intervention study was performed using a B. pilosicoli challenge model in poultry to elucidate the potential for probiotic intervention against AIS. This study demonstrated that when administered in drinking water, L. reuteri LM1, isolated from a healthy chicken, reduced all aspects of the clinical presentation of AIS.

Subjects/Keywords: 616.9272; Brachyspira; Avian intestinal spirochaetosis; Poultry; Probiotics; Lactobacillus; Biolog Phenotype MicroArray; Genome sequencing; Comparative genomics; Three-dimensional cell culture; In vitro organ culture; Experimental challenge

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APA (6^th Edition):

Mappley, L. J. (2012). Understanding the pathobiology of Brachyspira pilosicoli in order to develop novel intervention strategies against avian intestinal spirochaetosis. (Doctoral Dissertation). Royal Holloway, University of London. Retrieved from https://pure.royalholloway.ac.uk/portal/en/publications/understanding-the-pathobiology-of-brachyspira-pilosicoli-in-order-to-develop-novel-intervention-strategies-against-avian-intestinal-spirochaetosis(c71a3915-d765-4aa0-9932-b75434b4cd68).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.580621

Chicago Manual of Style (16^th Edition):

Mappley, Luke John. “Understanding the pathobiology of Brachyspira pilosicoli in order to develop novel intervention strategies against avian intestinal spirochaetosis.” 2012. Doctoral Dissertation, Royal Holloway, University of London. Accessed April 17, 2021. https://pure.royalholloway.ac.uk/portal/en/publications/understanding-the-pathobiology-of-brachyspira-pilosicoli-in-order-to-develop-novel-intervention-strategies-against-avian-intestinal-spirochaetosis(c71a3915-d765-4aa0-9932-b75434b4cd68).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.580621.

MLA Handbook (7^th Edition):

Mappley, Luke John. “Understanding the pathobiology of Brachyspira pilosicoli in order to develop novel intervention strategies against avian intestinal spirochaetosis.” 2012. Web. 17 Apr 2021.

Vancouver:

Mappley LJ. Understanding the pathobiology of Brachyspira pilosicoli in order to develop novel intervention strategies against avian intestinal spirochaetosis. [Internet] [Doctoral dissertation]. Royal Holloway, University of London; 2012. [cited 2021 Apr 17]. Available from: https://pure.royalholloway.ac.uk/portal/en/publications/understanding-the-pathobiology-of-brachyspira-pilosicoli-in-order-to-develop-novel-intervention-strategies-against-avian-intestinal-spirochaetosis(c71a3915-d765-4aa0-9932-b75434b4cd68).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.580621.

Council of Science Editors:

Mappley LJ. Understanding the pathobiology of Brachyspira pilosicoli in order to develop novel intervention strategies against avian intestinal spirochaetosis. [Doctoral Dissertation]. Royal Holloway, University of London; 2012. Available from: https://pure.royalholloway.ac.uk/portal/en/publications/understanding-the-pathobiology-of-brachyspira-pilosicoli-in-order-to-develop-novel-intervention-strategies-against-avian-intestinal-spirochaetosis(c71a3915-d765-4aa0-9932-b75434b4cd68).html ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.580621

University of Stirling

8. Delannoy, Christian M J. Host adaptation of aquatic Streptococcus agalactiae.

Degree: PhD, 2013, University of Stirling

URL: http://hdl.handle.net/1893/17259

► Streptococcus agalactiae is a pathogen of multiple hosts. The bacterium, an aetiological agent of septicaemia and meningo-encephalitis in freshwater and saltwater fish species, is considered… (more)

▼ Streptococcus agalactiae is a pathogen of multiple hosts. The bacterium, an aetiological agent of septicaemia and meningo-encephalitis in freshwater and saltwater fish species, is considered a major threat to the aquaculture industry, particularly for tilapia. Cattle and humans are however the main known reservoirs for S. agalactiae. In humans, the bacterium (commonly referred to as Group B Streptococcus or GBS) is a member of the commensal microflora of the intestinal and genito-urinary tracts, but it is also a major cause of neonatal invasive disease and an emerging pathogen in adults. In cattle, S. agalactiae is a well-recognized causative agent of mastitis. Numerous studies focusing on S. agalactiae from human and bovine origins have provided insight into the population structure of the bacterium, as well as the genome content and pathogenic mechanisms through identification of virulence determinants. Concerning S. agalactiae from aquatic origins, scientific information mainly focused on case reporting and/or experimental challenges, with a limited or absence of information in terms of pathogenesis, virulence determinants and genotypes of the strains involved. The objective of this study was to enhance our understanding of the molecular epidemiology, host-adaptation and pathogenicity of S. agalactiae in aquatic species, with particular emphasis on tilapia. Firstly, a collection of 33 piscine, amphibian and sea mammal isolates originating from several countries and continents was assembled, with the aim of exploring the population structure and potential host specificity of aquatic S. agalactiae. Isolates were characterised using pulsed-field gel electrophoresis (PFGE), multi-locus sequence typing (MLST), and a standardised 3-set genotyping system comprising molecular serotypes, surface protein gene profiles and mobile genetic element profiles. Two major subpopulations were identified in fish. The first subpopulation consisted of non-haemolytic isolates that belonged to sequence type (ST) 260 or 261, which are STs that have been reported only from teleosts. These isolates exhibited a low level of genetic diversity by PFGE and clustered with other STs that have been reported only in fish. Another common feature was the absence of all surface protein genes or mobile genetic elements targeted as part of the 3-set genotyping and that are usually found in human or bovine isolates. The second subpopulation consisted of β-haemolytic isolates recovered from fish, frogs and sea mammals, and that exhibited medium to high genetic diversity by PFGE. STs identified among these isolates have previously been identified from strains associated with asymptomatic carriage and invasive disease in humans. The human pathogenic strain ST7 serotype Ia was detected in fish from Asia. Moreover, ST283 serotype III-4 and its novel single locus variant ST491 detected in fish from Southeast Asia shared a 3-set genotype identical to that of an emerging ST283 clone associated with invasive disease of adult humans in Asia. These observations…

Subjects/Keywords: Streptococcus agalactiae; Fish; Sea mammal; Aquatic epidemiology; Molecular epidemiology; MLST; PFGE; Experimental challenge; ST260; ST23; Pathology; Histopathology; IHC; Comparative genomics; Genome; Niche restriction; Virulence determinants; Aquatic animals Diseases; Aquatic animals Parasites; Fishes Diseases; Fishes Parasites; Streptococcus agalactiae

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APA (6^th Edition):

Delannoy, C. M. J. (2013). Host adaptation of aquatic Streptococcus agalactiae. (Doctoral Dissertation). University of Stirling. Retrieved from http://hdl.handle.net/1893/17259

Chicago Manual of Style (16^th Edition):

Delannoy, Christian M J. “Host adaptation of aquatic Streptococcus agalactiae.” 2013. Doctoral Dissertation, University of Stirling. Accessed April 17, 2021. http://hdl.handle.net/1893/17259.

MLA Handbook (7^th Edition):

Delannoy, Christian M J. “Host adaptation of aquatic Streptococcus agalactiae.” 2013. Web. 17 Apr 2021.

Vancouver:

Delannoy CMJ. Host adaptation of aquatic Streptococcus agalactiae. [Internet] [Doctoral dissertation]. University of Stirling; 2013. [cited 2021 Apr 17]. Available from: http://hdl.handle.net/1893/17259.

Council of Science Editors:

Delannoy CMJ. Host adaptation of aquatic Streptococcus agalactiae. [Doctoral Dissertation]. University of Stirling; 2013. Available from: http://hdl.handle.net/1893/17259

University of Illinois – Urbana-Champaign

9. Abdildin, Yerkin. Multiattribute utility functions for the deep borehole filter restoration problem.

Degree: PhD, 0127, 2014, University of Illinois – Urbana-Champaign

URL: http://hdl.handle.net/2142/50440

► The energy problem is one of the biggest challenges facing the World in the 21st century. It is related to the issues of natural resource… (more)

▼ The energy problem is one of the biggest challenges facing the World in the 21st century. It is related to the issues of natural resource extraction, resource depletion, power generation, environmental degradation, and atmospheric change such as global warming. Since more than 80% of the world’s primary energy is generated from fossil fuels (coal, oil, gas), emissions of carbon dioxide (CO2) from all fossil-fuel burnings are the largest cause of climate change. Global climate disruption, in turn, impacts on human health, flora, and fauna. The global energy demand is expected to double by 2050 and that is inevitably due to global population growth, global economic growth, and continued urbanization. To meet the increasing demand for energy and to avoid catastrophic climate change, increases in energy efficiency and increases in the fraction of low carbon energy sources are required. Uranium is a good energy source, because it has high energy density and nuclear power does not contribute to carbon dioxide emissions. However, difficulties in uranium mining cause large worldwide shortages of uranium for power generation. Decision makers in uranium mining are often challenged by various uncertainties in their decision problems (financial, technological, geological) and multiple objectives (increase profits, decrease radiation hazards, improve safety of operations, preserve environments). This dissertation studies multiattribute utility functions for modeling such challenging decision problems using the example of the deep borehole filter restoration problem from the uranium extraction industry. In this problem, the filter of the production borehole (or well) is periodically contaminated or clogged, causing significant uranium output reduction. The efficient modeling of this decision-making problem is of paramount importance for uranium mining worldwide and requires normative decision analysis. Motivated by the complexity of multiattribute decision problems under uncertainty and multiple objectives, this dissertation considers a set of open research problems related to the number of attributes and their degree of ‘interdependence under uncertainty,’ formally, utility dependence and independence. This dissertation characterizes the special functional forms of multiattribute utility functions (MUFs) under the partial utility independence (PUI) condition, verifies their applicability to the deep borehole filter restoration problem, evaluates the alternatives of the decision problem by three different approaches, and introduces novel methods for excluding redundant utility assessments. In Part I of this work we present our study: (1) what are the objectives and the corresponding attributes (i.e. factors or criteria of the decision-making process) of the deep borehole filter restoration problem from the well-field manager’s point of view, (2) does the ultimate decision maker find these attributes good or not, (3) does utility independence (UI) among the attributes exist in this decision problem, (4) whether or not… Advisors/Committee Members: Abbas, Ali E. (advisor), Abbas, Ali E. (Committee Chair), Uddin, Rizwan (committee member), Sreenivas, Ramavarapu S. (committee member), Allison, James T. (committee member).

Subjects/Keywords: Decision analysis; multiattribute utility functions; the World’s biggest challenge; energy problem; uranium mining; in situ leach mining; deep borehole filter restoration problem; borehole recovery problem; nuclear power; twos-complement exclusion algorithm; ternary-decimal exclusion algorithm; partial utility independence; utility assessments; preference elicitation; decision maker; evaluation of alternatives; multiple attributes; uncertainty; eliminating redundancy; excluding duplicate terms; experimental study; confidence intervals

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Abdildin, Y. (2014). Multiattribute utility functions for the deep borehole filter restoration problem. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/50440

Chicago Manual of Style (16^th Edition):

Abdildin, Yerkin. “Multiattribute utility functions for the deep borehole filter restoration problem.” 2014. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed April 17, 2021. http://hdl.handle.net/2142/50440.

MLA Handbook (7^th Edition):

Abdildin, Yerkin. “Multiattribute utility functions for the deep borehole filter restoration problem.” 2014. Web. 17 Apr 2021.

Vancouver:

Abdildin Y. Multiattribute utility functions for the deep borehole filter restoration problem. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2014. [cited 2021 Apr 17]. Available from: http://hdl.handle.net/2142/50440.

Council of Science Editors:

Abdildin Y. Multiattribute utility functions for the deep borehole filter restoration problem. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2014. Available from: http://hdl.handle.net/2142/50440

10. Pack, Jessica Spencer. Effect of Localized Temperature Change on Vigilance Performance.

Degree: MS, Human Factors and Industrial/Organizational Psychology MS, 2015, Wright State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=wright1429286666

► This study examined the influence of localized temperature change on vigilance performance. Additionally, the effect of stressor appraisals on the relationship between localized temperature change… (more)

Subjects/Keywords: Behavioral Psychology; Cognitive Psychology; Climate Change; Experimental Psychology; Personality Psychology; Physiological Psychology; Psychobiology; Psychology; vigilance; temperature; stressor appraisals; challenge; threat

…automated human-machine systems, and this observed deficiency initiated the experimental study of… …simulated radar task known as the ‘clock test’ (1948/1950). During the experimental… …manner, and the experimental sessions were long, lasting for 2 hours. This type of experimental… …experimental control to examine the effects of temperature on vigilance performance. The present… …x29;. Stressor appraisals reflect challenge when a person believes they have adequate…

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Pack, J. S. (2015). Effect of Localized Temperature Change on Vigilance Performance. (Masters Thesis). Wright State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=wright1429286666

Chicago Manual of Style (16^th Edition):

Pack, Jessica Spencer. “Effect of Localized Temperature Change on Vigilance Performance.” 2015. Masters Thesis, Wright State University. Accessed April 17, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=wright1429286666.

MLA Handbook (7^th Edition):

Pack, Jessica Spencer. “Effect of Localized Temperature Change on Vigilance Performance.” 2015. Web. 17 Apr 2021.

Vancouver:

Pack JS. Effect of Localized Temperature Change on Vigilance Performance. [Internet] [Masters thesis]. Wright State University; 2015. [cited 2021 Apr 17]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=wright1429286666.

Council of Science Editors:

Pack JS. Effect of Localized Temperature Change on Vigilance Performance. [Masters Thesis]. Wright State University; 2015. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=wright1429286666

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