subject:(Ethylene glycol)

University of Georgia

1. DiRamio, Jacqueline Adele. Polyethylene glycol methacrylate/dimethacrylate hydrogels for controlled release of hydrophobic drugs.

Degree: 2014, University of Georgia

URL: http://hdl.handle.net/10724/22093

► We report on the release characteristics of a model hydrophobic drug, estradiol, entrapped in polyethylene glycol methacrylate (PEG-MA)/dimethacrylate (PEG-DMA) hydrogels. The crosslinking ratio, temperature, and… (more)

Subjects/Keywords: poly(ethylene glycol methacrylate); poly(ethylene glycol dimethcrylate); hydrogels; estradiol; insulin; hydrophobic drug release; ethanol

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

DiRamio, J. A. (2014). Polyethylene glycol methacrylate/dimethacrylate hydrogels for controlled release of hydrophobic drugs. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/22093

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

DiRamio, Jacqueline Adele. “Polyethylene glycol methacrylate/dimethacrylate hydrogels for controlled release of hydrophobic drugs.” 2014. Thesis, University of Georgia. Accessed March 06, 2021. http://hdl.handle.net/10724/22093.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

DiRamio, Jacqueline Adele. “Polyethylene glycol methacrylate/dimethacrylate hydrogels for controlled release of hydrophobic drugs.” 2014. Web. 06 Mar 2021.

Vancouver:

DiRamio JA. Polyethylene glycol methacrylate/dimethacrylate hydrogels for controlled release of hydrophobic drugs. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Mar 06]. Available from: http://hdl.handle.net/10724/22093.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

DiRamio JA. Polyethylene glycol methacrylate/dimethacrylate hydrogels for controlled release of hydrophobic drugs. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/22093

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

2. Georges, Mathias. Approche du frittage SPS de céramiques fines de carbure de bore : rôle des poudres initiales et de la mise en forme : SPS sintering approach to fine boron carbide ceramics : role of initial powders and forming.

Degree: Docteur es, Matériaux Céramiques et Traitements de Surface, 2016, Limoges

URL: http://www.theses.fr/2016LIMO0132

►

Le frittage par le procédé Spark Plasma Sintering (SPS) de céramiques denses de carbure de bore sans ajout d’additifs de frittage a été investi. L’effet… (more)

▼

Le frittage par le procédé Spark Plasma Sintering (SPS) de céramiques denses de carbure de bore sans ajout d’additifs de frittage a été investi. L’effet de la mise en forme de la poudre de carbure de bore a été étudié. Dans ce cadre, une étude sur la mise en suspension de la poudre commerciale a été menée, quatre solvants permettant l’obtention de suspensions stables ont ainsi été identifiés (eau dés-ionisée, mélange eau dés-ionisée/tétraméthylamonium, acide oléique et éthylène glycol). Des valeurs de densité relative à cru plus élevées ont été obtenues par voie liquide et coulage naturel par rapport à celles des crus obtenus par pressage uniaxiale. De plus, le cycle de frittage SPS a été optimisé notamment sur la base de certains paramètres (température, temps du palier isotherme, contrainte uniaxiale appliquée). Les cinétiques de densification associées ont conduit à l’établissement d’une carte de frittage SPS du carbure de bore. Cette dernière a mis en évidence un large domaine de valeurs de densité relative (comprises entre 84 et 97%), pour lequel le phénomène de croissance granulaire est peu présent. La confrontation des données expérimentales avec le modèle viscoplastique d’Olevsky a conduit à identifier les mécanismes de densification sur la base notamment des valeurs d’exposant de contrainte (de l’ordre de 3-4) et d’énergie d’activation apparente (112 kJ.mol-1). Ainsi, il a été démontré que la consolidation du carbure de bore était assistée par un mécanisme de déformation plastique gouverné par des mouvements de dislocations. Les observations microstructurales suggèrent également l’existence d’un phénomène de maclage à haute température. En parallèle, une instrumentation spécifique a été mise en place permettant d’identifier les caractéristiques de fonctionnement du générateur de courant pulsé. Sur la base de ces données électriques, un modèle numérique robuste par éléments finis du procédé SPS a été établi. Le développement de ce modèle numérique a permis d’optimiser le passage au frittage de céramique de carbure de bore de plus grande dimension. Ce changement d’échelle a nécessité l’optimisation de paramètres tels que la température de frittage ou encore les caractéristiques géométriques de la matrice.

Sintering of dense boron carbide ceramics by Spark Plasma Sintering (SPS) without sintering additives was investigated. The shaping effect of the commercial boron carbide powder was analysed. In this context, a study on the suspension of the powder was carried out, and four solvents allowing to obtain stable suspensions were thus identified (deionized water, mixture of deionized water/tetramethylammonium, oleic acid and ethylene glycol). Higher green relative densities were obtained by the liquid route and slip casting compared to those obtained by uniaxial pressing. In addition, the SPS sintering cycle has been optimized based on these parameters: temperature, isothermal dwell-time, applied uniaxial stress. The associated densification kinetics led to the establishment of a sintering map for SPS treatment…

Advisors/Committee Members: Maître, Alexandre (thesis director), Antou, Guy (thesis director), Pradeilles, Nicolas (thesis director).

Subjects/Keywords: Tétraméthylamonium; Acide oléique; Éthylène glycol; Tetraméthylamonium; Oleic acid; Ethylene glycol; 620.140 4

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Georges, M. (2016). Approche du frittage SPS de céramiques fines de carbure de bore : rôle des poudres initiales et de la mise en forme : SPS sintering approach to fine boron carbide ceramics : role of initial powders and forming. (Doctoral Dissertation). Limoges. Retrieved from http://www.theses.fr/2016LIMO0132

Chicago Manual of Style (16^th Edition):

Georges, Mathias. “Approche du frittage SPS de céramiques fines de carbure de bore : rôle des poudres initiales et de la mise en forme : SPS sintering approach to fine boron carbide ceramics : role of initial powders and forming.” 2016. Doctoral Dissertation, Limoges. Accessed March 06, 2021. http://www.theses.fr/2016LIMO0132.

MLA Handbook (7^th Edition):

Georges, Mathias. “Approche du frittage SPS de céramiques fines de carbure de bore : rôle des poudres initiales et de la mise en forme : SPS sintering approach to fine boron carbide ceramics : role of initial powders and forming.” 2016. Web. 06 Mar 2021.

Vancouver:

Georges M. Approche du frittage SPS de céramiques fines de carbure de bore : rôle des poudres initiales et de la mise en forme : SPS sintering approach to fine boron carbide ceramics : role of initial powders and forming. [Internet] [Doctoral dissertation]. Limoges; 2016. [cited 2021 Mar 06]. Available from: http://www.theses.fr/2016LIMO0132.

Council of Science Editors:

Georges M. Approche du frittage SPS de céramiques fines de carbure de bore : rôle des poudres initiales et de la mise en forme : SPS sintering approach to fine boron carbide ceramics : role of initial powders and forming. [Doctoral Dissertation]. Limoges; 2016. Available from: http://www.theses.fr/2016LIMO0132

3. Kalldin, Sofie. Lamination of Organic Solar Modules.

Degree: The Institute of Technology, 2014, Linköping UniversityLinköping University

URL: http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-105629

► As the Worlds energy demand is increasing we need more of our energy to be generated from resources that affect the climate as little… (more)

Subjects/Keywords: Organic solar modules; Lamination; PEDOT:PSS; Ethylene Glycol (EG); Diethylene Glycol (DEG); Polyethylene Glycol (PEG); Roll to roll process (R2R)

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Kalldin, S. (2014). Lamination of Organic Solar Modules. (Thesis). Linköping UniversityLinköping University. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-105629

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kalldin, Sofie. “Lamination of Organic Solar Modules.” 2014. Thesis, Linköping UniversityLinköping University. Accessed March 06, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-105629.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kalldin, Sofie. “Lamination of Organic Solar Modules.” 2014. Web. 06 Mar 2021.

Vancouver:

Kalldin S. Lamination of Organic Solar Modules. [Internet] [Thesis]. Linköping UniversityLinköping University; 2014. [cited 2021 Mar 06]. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-105629.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kalldin S. Lamination of Organic Solar Modules. [Thesis]. Linköping UniversityLinköping University; 2014. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-105629

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

UCLA

4. Siegman, Shayne Nicholas. PEGylated poly(ethylene imine) as a copolymer for gene delivery from hyaluronic acid hydrogels.

Degree: Chemical Engineering, 2014, UCLA

URL: http://www.escholarship.org/uc/item/7r3390g6

► The effective delivery of DNA locally could increase the applicability of gene therapy in tissue regeneration and therapeutic angiogenesis. One promising approach is through use… (more)

Subjects/Keywords: Chemical engineering; gene delivery; hydrogel; poly(ethylene glycol); poly(ethylene imine); polyplex

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Siegman, S. N. (2014). PEGylated poly(ethylene imine) as a copolymer for gene delivery from hyaluronic acid hydrogels. (Thesis). UCLA. Retrieved from http://www.escholarship.org/uc/item/7r3390g6

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Siegman, Shayne Nicholas. “PEGylated poly(ethylene imine) as a copolymer for gene delivery from hyaluronic acid hydrogels.” 2014. Thesis, UCLA. Accessed March 06, 2021. http://www.escholarship.org/uc/item/7r3390g6.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Siegman, Shayne Nicholas. “PEGylated poly(ethylene imine) as a copolymer for gene delivery from hyaluronic acid hydrogels.” 2014. Web. 06 Mar 2021.

Vancouver:

Siegman SN. PEGylated poly(ethylene imine) as a copolymer for gene delivery from hyaluronic acid hydrogels. [Internet] [Thesis]. UCLA; 2014. [cited 2021 Mar 06]. Available from: http://www.escholarship.org/uc/item/7r3390g6.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Siegman SN. PEGylated poly(ethylene imine) as a copolymer for gene delivery from hyaluronic acid hydrogels. [Thesis]. UCLA; 2014. Available from: http://www.escholarship.org/uc/item/7r3390g6

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

5. 奥山, 義和. Influence of composition and powder/liquid ratio on setting characteristics and mechanical properties of autopolymerized hard direct denture reline resins based on methyl methacrylate and ethylene glycol dimethacrylate : MMA，EGDMAを主成分とする直接法用常温重合型硬質リライン材の硬化挙動と機械的性質に及ぼす成分および粉液比の影響.

Degree: 博士(歯学), 2014, Nagasaki University / 長崎大学

URL: http://hdl.handle.net/10069/36107

► We evaluated the influence of composition and powder/liquid (P/L) ratio on the setting characteristics and mechanical properties of autopolymerized hard direct denture reline resins composed… (more)

Subjects/Keywords: Ethylene glycol dimethacrylate; Mechanical properties; Methyl methacrylate; Reline resin; Setting characteristics

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

奥山, �. (2014). Influence of composition and powder/liquid ratio on setting characteristics and mechanical properties of autopolymerized hard direct denture reline resins based on methyl methacrylate and ethylene glycol dimethacrylate : MMA，EGDMAを主成分とする直接法用常温重合型硬質リライン材の硬化挙動と機械的性質に及ぼす成分および粉液比の影響. (Thesis). Nagasaki University / 長崎大学. Retrieved from http://hdl.handle.net/10069/36107

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

奥山, 義和. “Influence of composition and powder/liquid ratio on setting characteristics and mechanical properties of autopolymerized hard direct denture reline resins based on methyl methacrylate and ethylene glycol dimethacrylate : MMA，EGDMAを主成分とする直接法用常温重合型硬質リライン材の硬化挙動と機械的性質に及ぼす成分および粉液比の影響.” 2014. Thesis, Nagasaki University / 長崎大学. Accessed March 06, 2021. http://hdl.handle.net/10069/36107.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

奥山, 義和. “Influence of composition and powder/liquid ratio on setting characteristics and mechanical properties of autopolymerized hard direct denture reline resins based on methyl methacrylate and ethylene glycol dimethacrylate : MMA，EGDMAを主成分とする直接法用常温重合型硬質リライン材の硬化挙動と機械的性質に及ぼす成分および粉液比の影響.” 2014. Web. 06 Mar 2021.

Vancouver:

奥山 �. Influence of composition and powder/liquid ratio on setting characteristics and mechanical properties of autopolymerized hard direct denture reline resins based on methyl methacrylate and ethylene glycol dimethacrylate : MMA，EGDMAを主成分とする直接法用常温重合型硬質リライン材の硬化挙動と機械的性質に及ぼす成分および粉液比の影響. [Internet] [Thesis]. Nagasaki University / 長崎大学; 2014. [cited 2021 Mar 06]. Available from: http://hdl.handle.net/10069/36107.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

奥山 �. Influence of composition and powder/liquid ratio on setting characteristics and mechanical properties of autopolymerized hard direct denture reline resins based on methyl methacrylate and ethylene glycol dimethacrylate : MMA，EGDMAを主成分とする直接法用常温重合型硬質リライン材の硬化挙動と機械的性質に及ぼす成分および粉液比の影響. [Thesis]. Nagasaki University / 長崎大学; 2014. Available from: http://hdl.handle.net/10069/36107

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

6. ⼤森, 裕⼦. Fabrication of dispersible calcium phosphate nanocrystals via a modified Pechini method under non-stoichiometric conditions : 改良 Pechini 法による分散性リン酸カルシウムナノ粒⼦の開発.

Degree: 博士（歯学）, 2016, Osaka Dental University / 大阪歯科大学

URL: http://id.nii.ac.jp/1392/00000069/

►

Various techniques for preparing ceramic nanoparticles have been developed; however, most of them start from a preparation of precursor nanoparticles that are generally amorphous or… (more)

Subjects/Keywords: Acrylic Resins; Citric Acid; Ethylene Glycol; Hydroxyapatites; Nanoparticles; Nanotechnology; Particle Size

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

⼤森, �. (2016). Fabrication of dispersible calcium phosphate nanocrystals via a modified Pechini method under non-stoichiometric conditions : 改良 Pechini 法による分散性リン酸カルシウムナノ粒⼦の開発. (Thesis). Osaka Dental University / 大阪歯科大学. Retrieved from http://id.nii.ac.jp/1392/00000069/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

⼤森, 裕⼦. “Fabrication of dispersible calcium phosphate nanocrystals via a modified Pechini method under non-stoichiometric conditions : 改良 Pechini 法による分散性リン酸カルシウムナノ粒⼦の開発.” 2016. Thesis, Osaka Dental University / 大阪歯科大学. Accessed March 06, 2021. http://id.nii.ac.jp/1392/00000069/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

⼤森, 裕⼦. “Fabrication of dispersible calcium phosphate nanocrystals via a modified Pechini method under non-stoichiometric conditions : 改良 Pechini 法による分散性リン酸カルシウムナノ粒⼦の開発.” 2016. Web. 06 Mar 2021.

Vancouver:

⼤森 �. Fabrication of dispersible calcium phosphate nanocrystals via a modified Pechini method under non-stoichiometric conditions : 改良 Pechini 法による分散性リン酸カルシウムナノ粒⼦の開発. [Internet] [Thesis]. Osaka Dental University / 大阪歯科大学; 2016. [cited 2021 Mar 06]. Available from: http://id.nii.ac.jp/1392/00000069/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

⼤森 �. Fabrication of dispersible calcium phosphate nanocrystals via a modified Pechini method under non-stoichiometric conditions : 改良 Pechini 法による分散性リン酸カルシウムナノ粒⼦の開発. [Thesis]. Osaka Dental University / 大阪歯科大学; 2016. Available from: http://id.nii.ac.jp/1392/00000069/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of California – Berkeley

7. Celik, Fuat Emin. Novel Routes to Ethylene Glycol Synthesis via Acid-Catalyzed Carbonylation of Formaldehyde and Dimethoxymethane.

Degree: Chemical Engineering, 2010, University of California – Berkeley

URL: http://www.escholarship.org/uc/item/51d5h807

► Carbon-carbon bond forming carbonylation reactions were investigated as candidates to replace ethene epoxidation as the major source of ethylene glycol production. This work was motivated… (more)

▼ Carbon-carbon bond forming carbonylation reactions were investigated as candidates to replace ethene epoxidation as the major source of ethylene glycol production. This work was motivated by the potentially lower cost of carbon derived from synthesis gas as compared to ethylene. Synthesis gas can be produced from relatively abundant and cheap natural gas, coal, and biomass resources whereas ethylene is derived from increasingly scarce and expensive crude oil. From synthesis gas, a range of C1 compounds containing no C-C bonds, such as methanol, formaldehyde and its closely related acetals such as dimethoxymethane (DMM), can be readily obtained. Formaldehyde carbonylation was once used commercially to produce precursors to ethylene glycol. Previous investigations of this reaction were carried out in the liquid phase, and required high carbon monoxide pressures (tens to hundreds of atmospheres) to overcome the low solubility of carbon monoxide. At lower carbon monoxide pressures, the reaction of formaldehyde with itself, the Cannizzaro disproportionation reaction, becomes the dominant process. The focus of this work was to carry out the carbonylation of formaldehyde and DMM with high selectivity and activity towards ethylene glycol precursors without requiring harsh conditions. Formaldehyde carbonylation was investigated in the liquid-phase using methyl formate (MF) as the source of CO using silicotungstic acid and other heteropoly acids as the catalyst. Methyl glycolate (MG) and methyl methoxyacetate (MMAc), both precursors to ethylene glycol, were formed along with DMM and dimethyl ether (DME), the primary byproducts. Using MF as the CO source avoided the need to pressurize the headspace with high pressures of CO gas. The effects of formaldehyde source, reaction temperature, reaction time, and catalyst were investigated. Methoxymethanol, paraformaldehyde, 1,3,5-trioxane, and DMM were examined as sources of formaldehyde. The highest yields of methyl glycolate and methyl methoxyacetate were obtained using 1,3,5-trioxane as the source of formaldehyde. Release of carbon monoxide from MF was found to be slow and limited the rate of carbonylation. Of the heteropoly acids investigated, silicotungstic acid produced the highest yields of MG and MMAc, whereas methanesulfonic acid did not produce these products at similar acid loading. The difference in the effectiveness of heteropoly acids and methanesulfonic acid is ascribed to the role of the anion of the heteropoly acid, a soft base, in stabilizing the reactive intermediates involved in the carbonylation of formaldehyde. While using MF as the CO source provided milder conditions, the selectivity to ethylene glycol precursors was still low. To achieve high selectivity under mild conditions, a novel vapor-phase process was developed. By carrying out the reaction in the vapor phase, the need for high pressure to dissolve CO in a liquid was avoided, and by using the dimethyl acetal of formaldehyde, DMM, the need for water or alcohol was avoided. Using an acid…

Subjects/Keywords: Engineering, Chemical; Acid catalysis; Carbonylation; Ethylene Glycol; Formaldehyde; Heterogeneous catalysis; Zeolite

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Celik, F. E. (2010). Novel Routes to Ethylene Glycol Synthesis via Acid-Catalyzed Carbonylation of Formaldehyde and Dimethoxymethane. (Thesis). University of California – Berkeley. Retrieved from http://www.escholarship.org/uc/item/51d5h807

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Celik, Fuat Emin. “Novel Routes to Ethylene Glycol Synthesis via Acid-Catalyzed Carbonylation of Formaldehyde and Dimethoxymethane.” 2010. Thesis, University of California – Berkeley. Accessed March 06, 2021. http://www.escholarship.org/uc/item/51d5h807.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Celik, Fuat Emin. “Novel Routes to Ethylene Glycol Synthesis via Acid-Catalyzed Carbonylation of Formaldehyde and Dimethoxymethane.” 2010. Web. 06 Mar 2021.

Vancouver:

Celik FE. Novel Routes to Ethylene Glycol Synthesis via Acid-Catalyzed Carbonylation of Formaldehyde and Dimethoxymethane. [Internet] [Thesis]. University of California – Berkeley; 2010. [cited 2021 Mar 06]. Available from: http://www.escholarship.org/uc/item/51d5h807.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Celik FE. Novel Routes to Ethylene Glycol Synthesis via Acid-Catalyzed Carbonylation of Formaldehyde and Dimethoxymethane. [Thesis]. University of California – Berkeley; 2010. Available from: http://www.escholarship.org/uc/item/51d5h807

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Rochester

8. Van Hove, Amy H. (1987 - ). Enzymatically-responsive poly(ethylene glycol) hydrogels for the controlled delivery of therapeutic peptides.

Degree: PhD, 2015, University of Rochester

URL: http://hdl.handle.net/1802/29655

► Therapeutic angiogenesis holds great potential for treatment of ischemic tissues and in tissue engineering, where insufficient vascularization limits construct size, complexity, and anastomosis with host… (more)

▼ Therapeutic angiogenesis holds great potential for treatment of ischemic tissues and in tissue engineering, where insufficient vascularization limits construct size, complexity, and anastomosis with host vasculature. However, no FDA approved treatments exist to robustly enhance vascularization within ischemic tissue. Many proangiogenic approaches have been developed, often via delivery of angiogenic proteins or peptides. Peptides typically mimic the bioactivity of larger proteins or growth factors, and offer advantages over traditional protein delivery, including more versatile synthesis methods and increased stability in vivo. However, both proteins and peptides suffer from rapid clearance and poor pharmacokinetics when delivered systemically, motivating the development of controlled release systems. Enzymatically-responsive systems where delivery of protein drugs is controlled by the local tissue microenvironment have shown improved tissue healing over bolus protein delivery. Therefore, a hydrogel-based platform technology was developed to control and sustain peptide drug release via matrix metalloproteinase (MMP) activity. Poly(ethylene glycol) (PEG) hydrogels were formed by crosslinking norbornene functionalized multi-arm PEG with peptide drugs flanked by MMP substrates and terminal cysteine residues. In vitro bioactivity testing identified three peptides (Qk (from Vascular Endothelial Growth Factor), SPARC113, and SPARC118 (from Secreted Protein Acidic and Rich in Cysteine)) that retained bioactivity in their expected released forms (e.g., with residual amino acids left by MMP substrates after cleavage). Incorporation of these peptides into hydrogels flanked by MMPdegradable substrates successfully produced hydrogels with enzymatically-responsive hydrogel degradation and peptide release behaviors. Hydrogels degraded via bulk degradation, and peptide release was in close agreement with mass loss. Qk, SPARC113, and SPARC118-releasing hydrogels were confirmed to release bioactive components in vitro after MMP-mediated degradation. Further investigation revealed key peptide drug properties, specifically size and hydrophobicity, control the rate of hydrogel degradation and peptide release. When implanted subcutaneously, SPARC113 and SPARC118-releasing hydrogels both significantly increased vascular ingrowth compared to controls one week after implantation without significantly affecting vessel size. As the longitudinal availability of VEGF has been shown critical for bioactivity, alternate hydrogels were formed to provide temporal control over enzymatically-responsive release of the VEGF peptide mimic, Qk. MMP-degradable linkers with a variety of cleavage kinetics were used to tether Qk to hydrogels formed with non-degradable peptide crosslinks. Hydrogel degradation was successfully uncoupled from peptide release, and three of the linkers provided temporal control over enzymatically-responsive peptide release kinetics in vitro and in vivo. Qk was confirmed to be bioactive as released,…

Subjects/Keywords: Controlled release; Drug delivery; Hydrogel; Peptide; Poly(ethylene glycol); Stimuli-responsive

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Van Hove, A. H. (. -. ). (2015). Enzymatically-responsive poly(ethylene glycol) hydrogels for the controlled delivery of therapeutic peptides. (Doctoral Dissertation). University of Rochester. Retrieved from http://hdl.handle.net/1802/29655

Chicago Manual of Style (16^th Edition):

Van Hove, Amy H (1987 - ). “Enzymatically-responsive poly(ethylene glycol) hydrogels for the controlled delivery of therapeutic peptides.” 2015. Doctoral Dissertation, University of Rochester. Accessed March 06, 2021. http://hdl.handle.net/1802/29655.

MLA Handbook (7^th Edition):

Van Hove, Amy H (1987 - ). “Enzymatically-responsive poly(ethylene glycol) hydrogels for the controlled delivery of therapeutic peptides.” 2015. Web. 06 Mar 2021.

Vancouver:

Van Hove AH(-). Enzymatically-responsive poly(ethylene glycol) hydrogels for the controlled delivery of therapeutic peptides. [Internet] [Doctoral dissertation]. University of Rochester; 2015. [cited 2021 Mar 06]. Available from: http://hdl.handle.net/1802/29655.

Council of Science Editors:

Van Hove AH(-). Enzymatically-responsive poly(ethylene glycol) hydrogels for the controlled delivery of therapeutic peptides. [Doctoral Dissertation]. University of Rochester; 2015. Available from: http://hdl.handle.net/1802/29655

University of Rochester

9. Shubin, Andrew Dean (1986 - ). Poly(ethylene glycol) hydrogels for salivary gland regeneration.

Degree: PhD, 2016, University of Rochester

URL: http://hdl.handle.net/1802/31702

► Over 500,000 people worldwide are diagnosed with head and neck cancers yearly. Radiation, a mainstay of curative therapy, causes irreparable damage to the salivary gland… (more)

▼ Over 500,000 people worldwide are diagnosed with head and neck cancers yearly. Radiation, a mainstay of curative therapy, causes irreparable damage to the salivary gland acinar cells, which results in chronic dry mouth or xerostomia. Xerostomia negatively affects patient quality of life for which no current treatments can ameliorate. Recently, regenerative therapies utilizing the direct injection of primary submandibular gland (SMG) cells into irradiated salivary glands have shown promise in regenerating salivary gland tissues and partially restoring gland function. However, the amount of regeneration is variable and little is known about the mechanism of healing and the characteristics of primary SMG cells. To address these limitations we propose the use of poly(ethylene glycol) (PEG) hydrogels to enhance in vitro culture conditions and in vivo cellular transplantation. PEG is a “bio-inert” polymer which provides “blank-slate” to control and study specific cell-material interactions. Initial work focused on designing cytocompatible methods to encapsulate and culture primary SMG cells within PEG hydrogels. The minimization of radicals using thiol-ene versus methacrylate-based chain polymerizations of hydrogel macromers and the inclusion of cell-cell interactions through the formation of multicellular “spheres” supported the survival and proliferation of primary SMG cells within PEG hydrogels for a 14 day culture period. Genetic lineage tracing was employed to determine the in vivo origin of encapsulated cells and showed that the majority (>80%) of encapsulated cells come from acinar and duct populations. To improve PEG hydrogels as a tissue engineering platform, the effects of laminin incorporation and different forms of hydrogel degradation on the proliferation, development of acinar cell phenotypes, and epithelial morphogenesis of encapsulated SMG cells were explored. The encapsulation of SMG cells within enzymatically (e.g., via cell-dictated processes) degradable hydrogels resulted in increased expression of the acinar water channel Aquaporin-5 (AQP5) and cellular organization reminiscent of native gland tissue compared to SMG cells encapsulated in hydrogels with bulkhydrolytic degradability. Degradable hydrogels (either hydrolytic or enzymatic) supported the greatest amount of cellular proliferation versus non-degradable gels. PEG hydrogels were further utilized to study cells originating from acinar tissues in primary culture. Despite previous studies suggesting otherwise, genetic lineage tracing showed that acinar lineage cells compose a significant portion of primary SMG cells in culture. However, acinar lineage cells underwent significant changes in morphology and exhibited a ~100-fold decrease in expression of the acinar cell markers AQP5 and Mist1. Furthermore, many acinar-lineage cells express cytokeratins and proliferate, indicating a transition to a duct-cell like phenotype. This acinar cell plasticity has important underpinnings for salivary gland biology and tissue engineering as acinar cells are the…

Subjects/Keywords: Biomaterials; Exocrine biology; Hydrogel; Poly(ethylene glycol); Salivary gland; Tissue engineering

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Shubin, A. D. (. -. ). (2016). Poly(ethylene glycol) hydrogels for salivary gland regeneration. (Doctoral Dissertation). University of Rochester. Retrieved from http://hdl.handle.net/1802/31702

Chicago Manual of Style (16^th Edition):

Shubin, Andrew Dean (1986 - ). “Poly(ethylene glycol) hydrogels for salivary gland regeneration.” 2016. Doctoral Dissertation, University of Rochester. Accessed March 06, 2021. http://hdl.handle.net/1802/31702.

MLA Handbook (7^th Edition):

Shubin, Andrew Dean (1986 - ). “Poly(ethylene glycol) hydrogels for salivary gland regeneration.” 2016. Web. 06 Mar 2021.

Vancouver:

Shubin AD(-). Poly(ethylene glycol) hydrogels for salivary gland regeneration. [Internet] [Doctoral dissertation]. University of Rochester; 2016. [cited 2021 Mar 06]. Available from: http://hdl.handle.net/1802/31702.

Council of Science Editors:

Shubin AD(-). Poly(ethylene glycol) hydrogels for salivary gland regeneration. [Doctoral Dissertation]. University of Rochester; 2016. Available from: http://hdl.handle.net/1802/31702

10. Sitta, Elton Fabiano. Dinâmica oscilatória na eletrooxidação de etileno glicol.

Degree: Mestrado, Físico-Química, 2008, University of São Paulo

URL: http://www.teses.usp.br/teses/disponiveis/75/75131/tde-18042008-112255/ ;

►

No presente trabalho foram estudados alguns aspectos não lineares da catálise da oxidação de etileno glicol (EG) sob platina em meio alcalino (KOH). A dinâmica… (more)

▼

No presente trabalho foram estudados alguns aspectos não lineares da catálise da oxidação de etileno glicol (EG) sob platina em meio alcalino (KOH). A dinâmica do sistema foi investigada através de voltametria cíclica, séries temporais de corrente e potencial e por espectroscopia de impedância eletroquímica. (EIE). Os resultados da EIE revelaram a presença de uma região de resistência diferencial negativa escondida nas proximidades o pico principal obtido na voltametria cíclica. De modo geral o sistema se mostrou apto a oscilar tanto sob regime potenciostático quanto galvanostático e por longos períodos de tempo apresentando uma miríade de estados dinâmicos que incluem oscilações harmônicas, de baixa e alta amplitudes, períodos 2, 3, 4 e modos mistos, além da duplicação de período na transição para o caos. A concentração tanto de EG como de KOH tiveram caráter essencial nos padrões temporais observados. A complexidade dos períodos aumenta com o aumento da concentração de EG resultando em 90% do tempo em que o sistema passa oscilando devotado às oscilações caóticas quando a concentração de EG é de 1,6 M. O aumento da densidade de corrente produz um efeito contrário nos padrões, ou seja, quanto mais alta é a corrente mais simples são os períodos. A influência de alguns produtos de oxidação parcial do EG foi estudada em diferentes condições. Os resultados das mudanças de morfologia das oscilações são racionalizados em termos das eventuais conexões com os intermediários de reação formados durante o processo de oxidação que, por sua vez, dependem da concentração do álcool e da densidade de corrente.

In the present work were studied some nonlinear aspects of the catalytic oxidation of ethylene glycol (EG) on platinum electrodes in alkaline media (KOH). The system\'s dynamics was investigated by means of cyclic voltammetry, current and potential time series, and electrochemical impedance spectroscopy (EIS). The EIS results reveal the presence of a hidden negative differential resistance around the main voltammetric peak. Overall, the system was able to oscillate for several periods, displaying a myriad of dynamic states which includes harmonic, small and large amplitude, periods 2, 3, and 4, and mixed-mode oscillations, as well as period doubling transition to chaos. The concentration of both EG and KOH were found to play an essential role in the temporal patterns observed. The complexity of the periods increase with EG concentration resulting in 90% of the oscillating time devoted to chaotic patters when EG concentration is 1.6 M. The increment of the current density produces an opposite behavior of the patters: the higher the applied current the simpler the oscillatory dynamics. The influence of some products of partial EG oxidation was studied under different conditions and compared. The results of the changes in the oscillatory morphology are rationalized in terms of its eventual connection with reaction intermediates formed during the oxidation process that, in turn, depends on the alcohol concentration and on the…

Advisors/Committee Members: Albuquerque, Hamilton Brandão Varela de.

Subjects/Keywords: electrooxidation; eletrooxidação; ethylene glycol; etileno glicol; oscilações; oscillations

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APA (6^th Edition):

Sitta, E. F. (2008). Dinâmica oscilatória na eletrooxidação de etileno glicol. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/75/75131/tde-18042008-112255/ ;

Chicago Manual of Style (16^th Edition):

Sitta, Elton Fabiano. “Dinâmica oscilatória na eletrooxidação de etileno glicol.” 2008. Masters Thesis, University of São Paulo. Accessed March 06, 2021. http://www.teses.usp.br/teses/disponiveis/75/75131/tde-18042008-112255/ ;.

MLA Handbook (7^th Edition):

Sitta, Elton Fabiano. “Dinâmica oscilatória na eletrooxidação de etileno glicol.” 2008. Web. 06 Mar 2021.

Vancouver:

Sitta EF. Dinâmica oscilatória na eletrooxidação de etileno glicol. [Internet] [Masters thesis]. University of São Paulo; 2008. [cited 2021 Mar 06]. Available from: http://www.teses.usp.br/teses/disponiveis/75/75131/tde-18042008-112255/ ;.

Council of Science Editors:

Sitta EF. Dinâmica oscilatória na eletrooxidação de etileno glicol. [Masters Thesis]. University of São Paulo; 2008. Available from: http://www.teses.usp.br/teses/disponiveis/75/75131/tde-18042008-112255/ ;

11. Cunha, Natália Baraldi [UNESP]. Avaliação do papel da piridoxina na prevenção da nefrocalcinose induzida pela hiperoxalúria em ratos.

Degree: 2016, Universidade Estadual Paulista

URL: http://hdl.handle.net/11449/143838

► Introduction: The calcium oxalate is the major metabolic component involved in the formation of renal calculus. Therefore, different pharmacological approaches have been or are being… (more)

▼ Introduction: The calcium oxalate is the major metabolic component involved in the formation of renal calculus. Therefore, different pharmacological approaches have been or are being proposed for the treatment of nephrolithiasis by calcium oxalate. Among them, the pyridoxine, a component of vitamin B6, has been suggested as a potential therapeutic agent that can minimize the effects of hyperoxaluria. However, the results are controversial. Objective: To evaluate the effects of pyridoxine (vitamin B6) on the urinary excretion of oxalate and its possible impact on renal disorders caused by nephrocalcinosis induced from an experimental model of hyperoxaluria in rats. Methods: It was used 60 Sprague Dawley male rats and were randomized into four groups: Group 1 [(G1: n = 15) clinical control]; Group 2 [G2: Ethylene glycol (EG) 0.5% + Vitamin D3 (VD3), n = 15], which hyperoxaluria was induced by the administration of EG diluted in water and offered in association with VD3 (Cholecalciferol) at a dose of 0.5 uM; Group 3 [G3: 0.5% EG + VD3 + pyridoxine (VB6); n = 15], which the animals received the same drugs offered to the G2 plus VB6 at a dose of 180mg / kg body weight / day; Group 4 (G4, n = 15) which the animals are supplemented only with the same dose of VB6 in G3. All animals were euthanized after 28 days of intervention and submitted a metabolic study on the urine of 24 hours; histopathological / morphometric analysis of oxidative stress in renal parenchymal and spectroscopic measurement of calcium. Results: Among the urinary parameters evaluated, there was significant reduction in the citrate in G2 compared to the control group- G1 (781.9 and 2414.4mg / L, respectively), while the oxalate was significantly increased in G2 and G3 compared to G1 (7.79, 8.94 and 2.96mg / L, respectively). The urinary calcium was significantly lower in the induced groups (G3: 0.9, G2: 1.5 and G1: 2.25mg / dL). Histomorphometric analysis revealed that only the animals of G2 and G3 developed nephrocalcinosis without, however, no substantially differences from each other in the counting of intratubular crystals were found. Similarly, considering the histopathologic analysis, only the induced animals (G2 and G3) exhibited atrophy, stromal extravasation and inflammatory infiltrate in the renal parenchyma in a similar pattern between the two groups. Regarding to the analysis of oxidative stress, an increase of lipid hydroperoxide levels associated with reduced superoxide dismutase activity and glutathione peroxidase in the G2. In the other groups, the enzyme pattern remained relatively stable compared to the control, except for catalase activity, which activity proved to be increased in all groups. In the other groups, the enzyme pattern remained relatively stable compared to the control (G1), except for the catalase activity, in which activity increased in all groups. As expected, the quantification of calcium in the renal parenchyma was significantly higher in G2 and G3 as compared to groups without induction. Conclusion: Pyridoxine was not… Advisors/Committee Members: Kawano, Paulo Roberto [UNESP], Amaro, João Luiz [UNESP], Universidade Estadual Paulista (UNESP).

Subjects/Keywords: Piridoxina; Nefrocalcinose; Ratos; Etileno glicol; Pyridoxine; Nephrocalcinosis; Rats; Ethylene glycol

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APA (6^th Edition):

Cunha, N. B. [. (2016). Avaliação do papel da piridoxina na prevenção da nefrocalcinose induzida pela hiperoxalúria em ratos. (Thesis). Universidade Estadual Paulista. Retrieved from http://hdl.handle.net/11449/143838

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Cunha, Natália Baraldi [UNESP]. “Avaliação do papel da piridoxina na prevenção da nefrocalcinose induzida pela hiperoxalúria em ratos.” 2016. Thesis, Universidade Estadual Paulista. Accessed March 06, 2021. http://hdl.handle.net/11449/143838.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Cunha, Natália Baraldi [UNESP]. “Avaliação do papel da piridoxina na prevenção da nefrocalcinose induzida pela hiperoxalúria em ratos.” 2016. Web. 06 Mar 2021.

Vancouver:

Cunha NB[. Avaliação do papel da piridoxina na prevenção da nefrocalcinose induzida pela hiperoxalúria em ratos. [Internet] [Thesis]. Universidade Estadual Paulista; 2016. [cited 2021 Mar 06]. Available from: http://hdl.handle.net/11449/143838.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Cunha NB[. Avaliação do papel da piridoxina na prevenção da nefrocalcinose induzida pela hiperoxalúria em ratos. [Thesis]. Universidade Estadual Paulista; 2016. Available from: http://hdl.handle.net/11449/143838

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

12. Banumathi N. Corrosion mitigation effect of water soluble Poly Ethylene Glycol Substituted Aniline composites for mild steel in Hcl;.

Degree: Chemistry, 2011, Avinashilingam Deemed University For Women

URL: http://shodhganga.inflibnet.ac.in/handle/10603/6671

None

Summary p. 160-162, Bibliography p. 163-176

Advisors/Committee Members: Subhashini S.

Subjects/Keywords: Chemistry; Ethylene Glycol; Corrosion

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

N, B. (2011). Corrosion mitigation effect of water soluble Poly Ethylene Glycol Substituted Aniline composites for mild steel in Hcl;. (Thesis). Avinashilingam Deemed University For Women. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/6671

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

N, Banumathi. “Corrosion mitigation effect of water soluble Poly Ethylene Glycol Substituted Aniline composites for mild steel in Hcl;.” 2011. Thesis, Avinashilingam Deemed University For Women. Accessed March 06, 2021. http://shodhganga.inflibnet.ac.in/handle/10603/6671.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

N, Banumathi. “Corrosion mitigation effect of water soluble Poly Ethylene Glycol Substituted Aniline composites for mild steel in Hcl;.” 2011. Web. 06 Mar 2021.

Vancouver:

N B. Corrosion mitigation effect of water soluble Poly Ethylene Glycol Substituted Aniline composites for mild steel in Hcl;. [Internet] [Thesis]. Avinashilingam Deemed University For Women; 2011. [cited 2021 Mar 06]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/6671.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

N B. Corrosion mitigation effect of water soluble Poly Ethylene Glycol Substituted Aniline composites for mild steel in Hcl;. [Thesis]. Avinashilingam Deemed University For Women; 2011. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/6671

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Anna University

13. Thirumarimurugan, M. Certain investigations on the performance analysis of heat Exchangers for two phase systems Using artificial neural networks; -.

Degree: Technology, 2014, Anna University

URL: http://shodhganga.inflibnet.ac.in/handle/10603/27518

►

The main objective of the research work aims to study on the heat newlinetransfer characteristics of various heat exchangers namely Shell and Tube newlineHeat Exchanger… (more)

Subjects/Keywords: Ethylene Glycol Water System; Number of Transfer Units

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APA (6^th Edition):

Thirumarimurugan, M. (2014). Certain investigations on the performance analysis of heat Exchangers for two phase systems Using artificial neural networks; -. (Thesis). Anna University. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/27518

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Thirumarimurugan, M. “Certain investigations on the performance analysis of heat Exchangers for two phase systems Using artificial neural networks; -.” 2014. Thesis, Anna University. Accessed March 06, 2021. http://shodhganga.inflibnet.ac.in/handle/10603/27518.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Thirumarimurugan, M. “Certain investigations on the performance analysis of heat Exchangers for two phase systems Using artificial neural networks; -.” 2014. Web. 06 Mar 2021.

Vancouver:

Thirumarimurugan M. Certain investigations on the performance analysis of heat Exchangers for two phase systems Using artificial neural networks; -. [Internet] [Thesis]. Anna University; 2014. [cited 2021 Mar 06]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/27518.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Thirumarimurugan M. Certain investigations on the performance analysis of heat Exchangers for two phase systems Using artificial neural networks; -. [Thesis]. Anna University; 2014. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/27518

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Texas A&M University

14. Browning, Mary Beth. Development of Multilayer Vascular Grafts Based on Collagen-Mimetic Hydrogels.

Degree: PhD, Biomedical Engineering, 2013, Texas A&M University

URL: http://hdl.handle.net/1969.1/151247

► Current synthetic vascular grafts have high failure rates in small-diameter (<6 mm) applications due to inadequate cell-material interactions and poor matching of arterial biomechanical properties.… (more)

▼ Current synthetic vascular grafts have high failure rates in small-diameter (<6 mm) applications due to inadequate cell-material interactions and poor matching of arterial biomechanical properties. To address this, we have developed a multilayer vascular graft design with a non-thrombogenic inner layer that promotes endothelial cell (EC) interactions and a reinforcing layer with tunable biomechanical properties. The blood-contacting layer of the graft is based on a Streptococcal collagen-like protein (Scl2-1). Scl2-1 has the triple helical structure of collagen, but it is a non-thrombogenic protein that can be modified to have selective cell adhesion. For this application, Scl2-2 has been modified from Scl2-1 to contain integrin binding sites that promote EC adhesion. We have developed the methodology to incorporate Scl2 proteins into a poly(ethylene glycol) (PEG) hydrogel matrix. PEG-Scl2 hydrogels facilitate optimization of both bioactivity and substrate modulus to offer unique control over graft endothelialization. However, scaffold properties that promote endothelialization may not be consistent with the mechanical properties necessary to withstand physiological loading. To address this issue, we have reinforced PEG-Scl2-2 hydrogels with an electrospun polyurethane mesh. This multilayer vascular graft design decouples requisite mechanical properties from endothelialization processes and permits optimization of both design goals. We have confirmed the thromboresistance of PEG-Scl2-2 hydrogels in a series of whole blood tests in vitro as well as in a porcine carotid artery model. Additionally, we have shown that the electrospun mesh biomechanical properties can be tuned over a wide range to achieve comparable properties to current autologous grafts. Traditional acrylate-derivatized PEG (PEGDA) hydrogels were replaced with PEG diacrylamide hydrogels with similar properties to increase biostability for long-term implantation. These findings indicate that this multilayer design shows promise for vascular graft applications. As vascular graft endothelialization can significantly improve success rates, the ability to alter cell-material interactions through manipulations in PEG-Scl2-2 hydrogel properties was studied extensively. By reducing Scl2-2 functionalization density and utilizing a biostable PEG functionalization linker, Acrylamide-PEG-I, significantly improved initial EC adhesion was achieved that was maintained over 6 weeks of swelling in vitro. Additionally, increases in Scl2-2 concentration and in hydrogel modulus provided increased EC interactions. It was found that PEG-Scl2-2 hydrogels promoted enhanced EC proliferation over 1 week compared to PEG-collagen gels. In summary, we have developed a vascular graft with a biostable, non-thrombogenic intimal layer that promotes EC adhesion and migration while providing biomechanical properties comparable to current autologous grafts. This design demonstrates great potential as an off-the-shelf graft for small diameter arterial prostheses that improves… Advisors/Committee Members: Cosgriff-Hernandez, Elizabeth M. (advisor), Hahn, Mariah S. (committee member), Maitland, Duncan J. (committee member), Clubb, Fred J. (committee member).

Subjects/Keywords: Hydrogels; Poly(ethylene glycol); Scl2 Proteins; Vascular Graft

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APA (6^th Edition):

Browning, M. B. (2013). Development of Multilayer Vascular Grafts Based on Collagen-Mimetic Hydrogels. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/151247

Chicago Manual of Style (16^th Edition):

Browning, Mary Beth. “Development of Multilayer Vascular Grafts Based on Collagen-Mimetic Hydrogels.” 2013. Doctoral Dissertation, Texas A&M University. Accessed March 06, 2021. http://hdl.handle.net/1969.1/151247.

MLA Handbook (7^th Edition):

Browning, Mary Beth. “Development of Multilayer Vascular Grafts Based on Collagen-Mimetic Hydrogels.” 2013. Web. 06 Mar 2021.

Vancouver:

Browning MB. Development of Multilayer Vascular Grafts Based on Collagen-Mimetic Hydrogels. [Internet] [Doctoral dissertation]. Texas A&M University; 2013. [cited 2021 Mar 06]. Available from: http://hdl.handle.net/1969.1/151247.

Council of Science Editors:

Browning MB. Development of Multilayer Vascular Grafts Based on Collagen-Mimetic Hydrogels. [Doctoral Dissertation]. Texas A&M University; 2013. Available from: http://hdl.handle.net/1969.1/151247

University of Johannesburg

15. Sibiya, Mike Sbonelo. Catalytic transformation of propylene carbonate into dimethyl carbonate and propylene glycol.

Degree: 2008, University of Johannesburg

URL: http://hdl.handle.net/10210/418

►

Dialkyl carbonates are important industrial compounds that have a low toxicity and are readily biodegrade, also replacing some highly toxic and corrosive reagents in organic… (more)

▼

Dialkyl carbonates are important industrial compounds that have a low toxicity and are readily biodegrade, also replacing some highly toxic and corrosive reagents in organic chemistry. There are a number of synthetic routes towards the synthesis of dialkyl carbonates, including two commercial processes (ENIChem S.p.A. and UBE Industries, LTD). The ENIChem process involves the carbonylation of methanol in the presence of CuCl2 as a catalyst. The major drawback of this process is in the use of an explosive gas mixture (CO/O2) under certain conditions. The UBE process is a two step reaction, whereby the methanol reacts with O2 and NO in the presence of a PdCl2 catalyst to form methyl nitrite and water, followed by carbonylation of methyl nitrite to form DMC and reform NO. The major drawback associated with this process is in the combination of methanol, nitric oxide and oxygen which is also explosive under some conditions. The transesterification reaction between a cyclic carbonate and an alcohol in the presence of a catalyst provide an alternative route towards synthesis of dialkyl carbonates, producing a glycol as by-product. This synthetic route is environmentally friendly, decreases explosion possibilities, and the reagents employed in this process are less hazardous than those of other processes. The main aim of this study was to identify and optimise the catalyst systems that could promote the transesterification reaction effectively. A number of homogeneous and heterogeneous, acidic or basic catalysts were evaluated during this study. The study revealed that basic homogeneous catalysts such as TBD, DBU, DBN, MTBD, DABCO, and Verkade bases are effective for the transesterification reaction. The basic heterogeneous catalysts such as Amberlites® IRA 96, IRA 67 and IRA 400 showed good catalytic behaviour, but they eventually became deactivated. On the other hand, homogeneous Lewis acids such as La(OTf)3, Gd(OTf)3, and Sm(OTf)3 demonstrated good activity, even though they need high temperatures, i.e. 150 °C. The heterogeneous acidic systems such as Amberlyst® 15, Amberlyst® 36, silica, alumina, etc., showed much lower activity, if any was observed. ix Due to the fact that these reactions were carried out above room temperature and analysed at room temperature in the GC, it was important to understand the equilibrium shift under such temperature variations, and NMR studies were used here. There was no significant difference in equilibrium conversion between the NMR reactions and the autoclave reactions (analysed in a GC), indicating slight influence of temperature variation. The results obtained from the NMR study were used to calculate the reaction kinetics. The calculations indicated a direct proportional increase of the rate with respect to the catalysts pKa values.

Prof. D.B.G. Williams

Subjects/Keywords: catalysts; ethylene glycol; carbonates

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sibiya, M. S. (2008). Catalytic transformation of propylene carbonate into dimethyl carbonate and propylene glycol. (Thesis). University of Johannesburg. Retrieved from http://hdl.handle.net/10210/418

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sibiya, Mike Sbonelo. “Catalytic transformation of propylene carbonate into dimethyl carbonate and propylene glycol.” 2008. Thesis, University of Johannesburg. Accessed March 06, 2021. http://hdl.handle.net/10210/418.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sibiya, Mike Sbonelo. “Catalytic transformation of propylene carbonate into dimethyl carbonate and propylene glycol.” 2008. Web. 06 Mar 2021.

Vancouver:

Sibiya MS. Catalytic transformation of propylene carbonate into dimethyl carbonate and propylene glycol. [Internet] [Thesis]. University of Johannesburg; 2008. [cited 2021 Mar 06]. Available from: http://hdl.handle.net/10210/418.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sibiya MS. Catalytic transformation of propylene carbonate into dimethyl carbonate and propylene glycol. [Thesis]. University of Johannesburg; 2008. Available from: http://hdl.handle.net/10210/418

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

NSYSU

16. Chang, Chih-Li. Design and Synthesis of Semiconducting Polymers and Their Application in Visible Light-Driven Hydrogen Evolution and Skin-inspired Optoelectronics.

Degree: Master, Chemistry, 2018, NSYSU

URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0630118-120045

► The research field in this thesis involves the visible lightâdriven water splitting for hydrogen evolution and stretchable polymer lightâemitting diodes (PLED). In chapter two and… (more)

▼ The research field in this thesis involves the visible lightâdriven water splitting for hydrogen evolution and stretchable polymer lightâemitting diodes (PLED). In chapter two and chapter four, the diblock conjugated copolymer is used as the main structure. The conjugated copolymers have the properties of deformability, light weight, corrosion resistance and semiconducting, so they have favorable potential in the development of novel materials. In the photocatalysis systems, generating hydrogen through visible lightâdriven water splitting would be one of the best process to convert abundant solar energy into hydrogen energy with high energy density in an environmentally friendly manner. Therefore, in chapter two, we design and synthesize a series of cycloplatinated polymers with low band gap, and successfully make them into polymer dots. The series of cycloplatinated polymers exhibit energy gap of 2.01~2.03 eV. So that cycloplatinated polymers can effectively absorb and ultilize visible light. The platinum complex unit (PtPy-acac and PtIq-acac) is linked to a conjugated semiconducting polymer backbone through covalent bonding, which can effectively improve the photocatalytic activity of the conjugated semiconducting polymers. Under the same photocatalytic conditions, the hydrogen evolution rate of PFTFQ-PtPy15 Pdot (HER = 12.7 ï± 0.6 mmol h-1 g-1), which contain 15 mole% PtPy-acac monomer, can be enhanced 12-times higher than that of PFTFQ Pdot (HER = 1.3 ï± 0.1 mmol h-1 g-1). Compared to the blending-counterpart Pdot (HERmax = 5.46 mmol h-1 g-1), which blending with the same molar PtPy-acac monomer, the HER of PFTFQ-PtPy15 still exhibit over 2-times higher than that of physically blended one. In addition, compared with other Pdots systems, the enhancement of the photocatalytic reaction time and the eventual hydrogen productions is observed by utilizing the cycloplatinated Pdots as photocatalysys. In summary, this series of cycloplatinated polymers possess excellent photocatalytic performances. The other hand, integrating electronics with human is one of the most promising next-generation electronic technologies. Because it aims to seamlessly integrate electronics with the human body, the requirements of materials are stretchability and biocompatibility. The design of suitable materials also performing promising optoelectronic properties remains a big challenge. In chapter four, we design and combine functional fused aromatic rings (fluorene and benzothiadiazole) and biodegradable structures (ethylene glycol, triethylene glycol, and hexaethylene glycol) to create new diblock conjugated copolymers. We also adjusted the ratio of soft and hard phases to establish platform for determining the correlations among the chemical structures and the mechanical and optoelectronic properties. Furthermore, we will fabricate the stretchable polymer light-emitting diodes to verify the functions of our synthesized materials. It will be an important impact on the development of applications for flexible and stretchable electronics.… Advisors/Committee Members: Ming-Li Tsai (committee member), Yang-Hsiang Chanang-Hsiang Chanang- (chair), Ho-Hsiu Chou (chair).

Subjects/Keywords: Semiconducting polymers; Polymer dots; Photocatalysts; Biocompatible; Ethylene glycol; Stretchable optoelectronics

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APA (6^th Edition):

Chang, C. (2018). Design and Synthesis of Semiconducting Polymers and Their Application in Visible Light-Driven Hydrogen Evolution and Skin-inspired Optoelectronics. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0630118-120045

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Chang, Chih-Li. “Design and Synthesis of Semiconducting Polymers and Their Application in Visible Light-Driven Hydrogen Evolution and Skin-inspired Optoelectronics.” 2018. Thesis, NSYSU. Accessed March 06, 2021. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0630118-120045.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Chang, Chih-Li. “Design and Synthesis of Semiconducting Polymers and Their Application in Visible Light-Driven Hydrogen Evolution and Skin-inspired Optoelectronics.” 2018. Web. 06 Mar 2021.

Vancouver:

Chang C. Design and Synthesis of Semiconducting Polymers and Their Application in Visible Light-Driven Hydrogen Evolution and Skin-inspired Optoelectronics. [Internet] [Thesis]. NSYSU; 2018. [cited 2021 Mar 06]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0630118-120045.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Chang C. Design and Synthesis of Semiconducting Polymers and Their Application in Visible Light-Driven Hydrogen Evolution and Skin-inspired Optoelectronics. [Thesis]. NSYSU; 2018. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0630118-120045

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Queensland University of Technology

17. Rackemann, Darryn W. Production of levulinic acid and other chemicals from sugarcane fibre.

Degree: 2014, Queensland University of Technology

URL: https://eprints.qut.edu.au/72741/

Lignocellulosics represent a renewable resource for producing fuels and chemicals as an alternative to fossil resources. This study utilised an organic acid catalyst and a co-solvent to develop an environmentally friendly processing technology for the production of levulinic acid and furfural from a waste material, sugarcane fibre.

Subjects/Keywords: levulinic acid; furfural; ethylene glycol; solvolysis; bagasse; ester; sulfonic acid; lignocellulosics

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Rackemann, D. W. (2014). Production of levulinic acid and other chemicals from sugarcane fibre. (Thesis). Queensland University of Technology. Retrieved from https://eprints.qut.edu.au/72741/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Rackemann, Darryn W. “Production of levulinic acid and other chemicals from sugarcane fibre.” 2014. Thesis, Queensland University of Technology. Accessed March 06, 2021. https://eprints.qut.edu.au/72741/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Rackemann, Darryn W. “Production of levulinic acid and other chemicals from sugarcane fibre.” 2014. Web. 06 Mar 2021.

Vancouver:

Rackemann DW. Production of levulinic acid and other chemicals from sugarcane fibre. [Internet] [Thesis]. Queensland University of Technology; 2014. [cited 2021 Mar 06]. Available from: https://eprints.qut.edu.au/72741/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Rackemann DW. Production of levulinic acid and other chemicals from sugarcane fibre. [Thesis]. Queensland University of Technology; 2014. Available from: https://eprints.qut.edu.au/72741/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Delaware

18. Courtney, Timothy D. Experimental and computational analysis of acid catalysts for biomass conversion.

Degree: PhD, University of Delaware, Department of Chemical and Biochemical Engineering, 2014, University of Delaware

URL: http://udspace.udel.edu/handle/19716/16802

► The Earth's growing population and limited supply of fossil fuels implore us to develop alternatives in order to maintain our quality of life far into… (more)

▼ The Earth's growing population and limited supply of fossil fuels implore us to develop alternatives in order to maintain our quality of life far into the future. This need is only exacerbated by mounting evidence that sustained fossil fuel use is changing our climate with trillions of dollars in potential damage. Wind, solar, and nuclear power can help to address our energy need, but fossil fuels are also an invaluable feedstock for commodity chemicals and the production of consumer goods. A future driven by renewable energy therefore requires renewable routes to replace these chemicals. Biomass feedstocks are highly oxygenated, enabling a rich and diverse chemistry with immense potential, but also making it difficult to control reaction selectivity. Chemical engineers have spent 100 years learning to control the reaction network of fossil fuels, and must now extend that control to biomass. Catalysis is critical to the economic feasibility of these processes not only to accelerate reactions, but to selectively accelerate only those reactions most desirable. In this thesis, Density Functional Theory (DFT) calculations, experimental reactor kinetics, and catalyst characterization are collectively employed to investigate a survey of open questions in biomass processing. Particular emphasis is placed on understanding the catalytic systems holistically and developing models that include other salient features of the system beyond the simple catalyst that fits on an organic chemistry reaction arrow. Glycerol is an immensely promising biomass feedstock available in surplus as a waste product of biodiesel formation. With these depressed feedstock costs, it can be made economically viable to convert glycerol to acrolein. This reaction has been studied exhaustively in the gas phase catalyzed with a gaseous proton. More realistic reactor systems however often employ liquid-phase reactions for this chemistry in the interest of process intensification. Also of interest are analogous reactions with sorbitol or sugars which are challenging to vaporize at all. A DFT model was therefore constructed to explore glycerol dehydration in the aqueous phase and the impact of explicit solvent molecules on the chemistry. Participation of solvent molecules in the chemistry permitted some reactions which were impossible in the gas phase while inhibiting some that are known to be less significant. The end result better predicted the dominant reaction pathway observed in experimental systems. This study was followed by experimental work studying the dehydration of pure, liquid propylene glycol, in contrast to existing studies employed dilute, gas-phase feed streams. Using experiment and DFT models, Brønsted-acidic zeolites were compared to the catalytically-simpler mesoporous sulfonic-acid resin Amberlyst 36Dry in order to better understand the impact of the zeolite micropores and their oxide character. The zeolite was found to amplify the already high selectivity towards dehydration of the secondary carbocation, and also to inhibit a sequential… Advisors/Committee Members: Vlachos, Dionisios G.Chen, Jingguang G..

Subjects/Keywords: Biomass conversion.; Catalysts.; Acids.; Zeolites.; Glycerin.; Ethylene glycol.; Density functionals.

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Courtney, T. D. (2014). Experimental and computational analysis of acid catalysts for biomass conversion. (Doctoral Dissertation). University of Delaware. Retrieved from http://udspace.udel.edu/handle/19716/16802

Chicago Manual of Style (16^th Edition):

Courtney, Timothy D. “Experimental and computational analysis of acid catalysts for biomass conversion.” 2014. Doctoral Dissertation, University of Delaware. Accessed March 06, 2021. http://udspace.udel.edu/handle/19716/16802.

MLA Handbook (7^th Edition):

Courtney, Timothy D. “Experimental and computational analysis of acid catalysts for biomass conversion.” 2014. Web. 06 Mar 2021.

Vancouver:

Courtney TD. Experimental and computational analysis of acid catalysts for biomass conversion. [Internet] [Doctoral dissertation]. University of Delaware; 2014. [cited 2021 Mar 06]. Available from: http://udspace.udel.edu/handle/19716/16802.

Council of Science Editors:

Courtney TD. Experimental and computational analysis of acid catalysts for biomass conversion. [Doctoral Dissertation]. University of Delaware; 2014. Available from: http://udspace.udel.edu/handle/19716/16802

University of Ottawa

19. Cheng, Nan. The Development of Photosensitive Surfaces to Control Cell Adhesion and Form Cell Patterns .

Degree: 2012, University of Ottawa

URL: http://hdl.handle.net/10393/23248

► Cell adhesion is the first step of cell response to materials and the extracellular matrix (ECM), and is essential to all cell behaviours such as… (more)

Subjects/Keywords: Chitosan; Cell adhesion; Self-assembled monolayer (SAM); Nitrobenzyl; Poly(ethylene glycol)

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APA (6^th Edition):

Cheng, N. (2012). The Development of Photosensitive Surfaces to Control Cell Adhesion and Form Cell Patterns . (Thesis). University of Ottawa. Retrieved from http://hdl.handle.net/10393/23248

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Cheng, Nan. “The Development of Photosensitive Surfaces to Control Cell Adhesion and Form Cell Patterns .” 2012. Thesis, University of Ottawa. Accessed March 06, 2021. http://hdl.handle.net/10393/23248.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Cheng, Nan. “The Development of Photosensitive Surfaces to Control Cell Adhesion and Form Cell Patterns .” 2012. Web. 06 Mar 2021.

Vancouver:

Cheng N. The Development of Photosensitive Surfaces to Control Cell Adhesion and Form Cell Patterns . [Internet] [Thesis]. University of Ottawa; 2012. [cited 2021 Mar 06]. Available from: http://hdl.handle.net/10393/23248.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Cheng N. The Development of Photosensitive Surfaces to Control Cell Adhesion and Form Cell Patterns . [Thesis]. University of Ottawa; 2012. Available from: http://hdl.handle.net/10393/23248

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Bucknell University

20. Evans, Stephanie. Modeling Small Molecule Elution From a Hydrogel using a Microfluidic Technique.

Degree: 2011, Bucknell University

URL: https://digitalcommons.bucknell.edu/masters_theses/1

► Drug release from a fluid-contacting biomaterial is simulated using a microfluidic device with channels defined by solute-loaded hydrogel. In order to mimic a drug delivery… (more)

Subjects/Keywords: Hydrogels; Poly(ethylene glycol) diacrylate; Elution; Diffusion; Microfluidics; Chemical Engineering

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APA (6^th Edition):

Evans, S. (2011). Modeling Small Molecule Elution From a Hydrogel using a Microfluidic Technique. (Thesis). Bucknell University. Retrieved from https://digitalcommons.bucknell.edu/masters_theses/1

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Evans, Stephanie. “Modeling Small Molecule Elution From a Hydrogel using a Microfluidic Technique.” 2011. Thesis, Bucknell University. Accessed March 06, 2021. https://digitalcommons.bucknell.edu/masters_theses/1.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Evans, Stephanie. “Modeling Small Molecule Elution From a Hydrogel using a Microfluidic Technique.” 2011. Web. 06 Mar 2021.

Vancouver:

Evans S. Modeling Small Molecule Elution From a Hydrogel using a Microfluidic Technique. [Internet] [Thesis]. Bucknell University; 2011. [cited 2021 Mar 06]. Available from: https://digitalcommons.bucknell.edu/masters_theses/1.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Evans S. Modeling Small Molecule Elution From a Hydrogel using a Microfluidic Technique. [Thesis]. Bucknell University; 2011. Available from: https://digitalcommons.bucknell.edu/masters_theses/1

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Manchester

21. Laghari, Gul Mohammad. Preparation and properties of polybenzodioxane PIM-1 and its copolymers with poly(ethylene glycol).

Degree: PhD, 2011, University of Manchester

URL: https://www.research.manchester.ac.uk/portal/en/theses/preparation-and-properties-of-polybenzodioxane-pim1-and-its-copolymers-with-polyethylene-glycol(1b728ac9-9362-415d-ae6a-61dd3ffde884).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.539983

► This thesis describes the synthesis of soluble Polymer of Intrinsic Microporosity (PIM-1), fluoro-endcapped PIM-1 (F-PIM-1) and copolymers of F-PIM-1 with poly(ethylene glycol) monomethyl ether (MeOPEG).… (more)

▼ This thesis describes the synthesis of soluble Polymer of Intrinsic Microporosity (PIM-1), fluoro-endcapped PIM-1 (F-PIM-1) and copolymers of F-PIM-1 with poly(ethylene glycol) monomethyl ether (MeOPEG). The main aim of the project was to alter the porosity of microporous PIM-1 in three ways: (a) synthesis of copolymers of F-PIM-1 with MeOPEG (b) blending of PIM-1 with MeOPEG in various proportions; and (c) adsorption of MeOPEG from aqueous solution byPIM-1. PIM-1 and F-PIM-1 were synthesized by step growth polymerization of tetrafluoroterephthalonitrile (TFTPN) with 5,5',6,6'-tetrahydroxy-3,3,3',3'-tetramethyl-1,1'-spirobisindane (THSB), using the conventional method and a newly reported high shear mixing method. F-PIM-1 oligomers were then coupled to poly(ethylene glycol) monomethyl ether (MeOPEG). The products were analyzed by NMR, IR, MALDI ToF MSS, TGA and polystyrene based GPC as well as multidetector GPC techniques. The high shear technique generally produced high molar mass products and yields. This method was also more successful for copolymerization.Blending of PIM-1 and MeOPEG in different proportions resulted in macrophase separation. Copolymer products were used to facilitate mixing of blends (as compatibilizers), however only 5% of MeOPEG could be solubilised into a PIM-1 phase. The effect of compatibilizer was found to be affected by interaction between PIM-1 and copolymer. However, N2 adsorption studies showed that after thermal removal of MeOPEG, PIM-1 regained stable porosity with significant BET surface area.Fluorescence studies were aimed at applications of PIM-1 and copolymers in sensors. PIM-1 and copolymers, spin-coated on the polyester-based substrate Melinex, were studied with and without methanol treatment in an environment of different solvent vapours. The effect of time and volume on wavelength shift and change in intensity was studied. Polar solvents tended to cause a red shift with decrease in intensity while less polar solvents behaved otherwise. Based on fluorescence experiments, solvent profiles for PIM-1 and copolymers were established.

Subjects/Keywords: 547.7; Polymers of Intrinsic microporosity, copolymers, poly(ethylene glycol), fluorescence, blends

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APA (6^th Edition):

Laghari, G. M. (2011). Preparation and properties of polybenzodioxane PIM-1 and its copolymers with poly(ethylene glycol). (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/preparation-and-properties-of-polybenzodioxane-pim1-and-its-copolymers-with-polyethylene-glycol(1b728ac9-9362-415d-ae6a-61dd3ffde884).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.539983

Chicago Manual of Style (16^th Edition):

Laghari, Gul Mohammad. “Preparation and properties of polybenzodioxane PIM-1 and its copolymers with poly(ethylene glycol).” 2011. Doctoral Dissertation, University of Manchester. Accessed March 06, 2021. https://www.research.manchester.ac.uk/portal/en/theses/preparation-and-properties-of-polybenzodioxane-pim1-and-its-copolymers-with-polyethylene-glycol(1b728ac9-9362-415d-ae6a-61dd3ffde884).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.539983.

MLA Handbook (7^th Edition):

Laghari, Gul Mohammad. “Preparation and properties of polybenzodioxane PIM-1 and its copolymers with poly(ethylene glycol).” 2011. Web. 06 Mar 2021.

Vancouver:

Laghari GM. Preparation and properties of polybenzodioxane PIM-1 and its copolymers with poly(ethylene glycol). [Internet] [Doctoral dissertation]. University of Manchester; 2011. [cited 2021 Mar 06]. Available from: https://www.research.manchester.ac.uk/portal/en/theses/preparation-and-properties-of-polybenzodioxane-pim1-and-its-copolymers-with-polyethylene-glycol(1b728ac9-9362-415d-ae6a-61dd3ffde884).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.539983.

Council of Science Editors:

Laghari GM. Preparation and properties of polybenzodioxane PIM-1 and its copolymers with poly(ethylene glycol). [Doctoral Dissertation]. University of Manchester; 2011. Available from: https://www.research.manchester.ac.uk/portal/en/theses/preparation-and-properties-of-polybenzodioxane-pim1-and-its-copolymers-with-polyethylene-glycol(1b728ac9-9362-415d-ae6a-61dd3ffde884).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.539983

22. Yancey, Benjamin Jacob. Ion Transport, Viscoelastic, and Thermal Properties of Several Poly(Ethylene Glycol) and Poly(Propylene Glycol) Based Polymer Electrolytes.

Degree: PhD, Chemistry, 2011, University of Mississippi

URL: https://egrove.olemiss.edu/etd/322

► This dissertation explores the relationship between ionic conductivity, viscosity, and thermal properties of several MePEG and MePPG based copolymer electrolytes. In particular two main copolymer… (more)

▼ This dissertation explores the relationship between ionic conductivity, viscosity, and thermal properties of several MePEG and MePPG based copolymer electrolytes. In particular two main copolymer modifications have been investigated namely copolymerization with "bulky groups" and cross polymerization of MePEG and MePPG monomers. The modifications were made to vary the fractional free volume of the MePEG polymers. All of the copolymers obeyed the Doolittle equation. For both the bulky copolymers and MePEG/MePPG copolymers, increases in the FFV corresponded to increases in the viscosity and decreases in FFV correspond to decreases in viscosity. The FFV and H+ conductivity for these copolymers were not correlated per the Forsythe equation. When the Vf,ether was substituted for FFV in the Forsythe equation, a strong correlation was observed indicating that the mechanism of proton conduction is dependent on the amount of ether units in the material. The viscosity and ionic conductivity for each individual copolymer electrolyte were correlated following the Walden rule. The ? values for all of the copolymer electrolytes were between 0.3 and 0.6 indicating that forces besides viscosity impede the ionic conductivity. These forces can include polymer rigidity, dissociation constant and the blocking of H+ channels. Most of the copolymer electrolytes had similar ? values which indicates that the same forces are affecting all of the copolymer electrolytes. The Cp showed a correlation to the activation energy for viscosity only for the MePPG3/MePPG2 copolymers. There was no correlation observed for all of the other copolymer electrolyte series. The correlation for the MePPG3/MePPG2 copolymers indicates that the molecular rearrangement in the material is dependent on the intermolecular forces present. There was no correlation observed between Cp and the activation energy for H+ conductivity for neither the high or low acid concentration MePEG/MePPG copolymers nor the low acid concentration bulky copolymers. The high acid concentration bulky copolymer electrolytes showed correlations for the copolymer series. The correlation increased as the polarity of the bulky groups increased with the exception the MePEG/Ph 2Si copolymers had the highest correlation. The correlations seen indicate that the bulky groups actually impede the H+ conductivity by altering the intermolecular forces in the materials. Lastly, the acid dissociation constant for the MePEG 7SO3H acid was measured. The acid dissociation was implicated as a contributing force that impedes ionic conductivity by the Walden plots. It was found that the pKa of the MePEG7SO3H decreased as the fraction of MePEG7OH increased in the binary solvent system. This corresponded to the acid weakening due to the fact that the pK a was actually further away from the pKa of the protonated solvent than in aqueous media. The mean activity coefficient also increased as the fraction of MePEG7SO3H increased. The results of the acid dissociation experiments further support the Grotthus mechanism… Advisors/Committee Members: Jason E. Ritchie, Richard Raspet, Amala Dass.

Subjects/Keywords: Conductivity; Free Volume Theory; Poly (Ethylene Glycol); Polymer Electrolyte; Viscosity; Chemistry

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APA (6^th Edition):

Yancey, B. J. (2011). Ion Transport, Viscoelastic, and Thermal Properties of Several Poly(Ethylene Glycol) and Poly(Propylene Glycol) Based Polymer Electrolytes. (Doctoral Dissertation). University of Mississippi. Retrieved from https://egrove.olemiss.edu/etd/322

Chicago Manual of Style (16^th Edition):

Yancey, Benjamin Jacob. “Ion Transport, Viscoelastic, and Thermal Properties of Several Poly(Ethylene Glycol) and Poly(Propylene Glycol) Based Polymer Electrolytes.” 2011. Doctoral Dissertation, University of Mississippi. Accessed March 06, 2021. https://egrove.olemiss.edu/etd/322.

MLA Handbook (7^th Edition):

Yancey, Benjamin Jacob. “Ion Transport, Viscoelastic, and Thermal Properties of Several Poly(Ethylene Glycol) and Poly(Propylene Glycol) Based Polymer Electrolytes.” 2011. Web. 06 Mar 2021.

Vancouver:

Yancey BJ. Ion Transport, Viscoelastic, and Thermal Properties of Several Poly(Ethylene Glycol) and Poly(Propylene Glycol) Based Polymer Electrolytes. [Internet] [Doctoral dissertation]. University of Mississippi; 2011. [cited 2021 Mar 06]. Available from: https://egrove.olemiss.edu/etd/322.

Council of Science Editors:

Yancey BJ. Ion Transport, Viscoelastic, and Thermal Properties of Several Poly(Ethylene Glycol) and Poly(Propylene Glycol) Based Polymer Electrolytes. [Doctoral Dissertation]. University of Mississippi; 2011. Available from: https://egrove.olemiss.edu/etd/322

University of Missouri – Columbia

23. Dasari, Mohanprasad A., 1979-. Catalytic conversion of glycerol and sugar alcohols to value-added products.

Degree: PhD, 2006, University of Missouri – Columbia

URL: https://doi.org/10.32469/10355/4331

► The current research is based on developing an improved and fundamental understanding of technology that will allow the conversion of this crude glycerin to a… (more)

Subjects/Keywords: Hydrogenolysis; Ethylene glycol; Chemical reactions

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APA (6^th Edition):

Dasari, Mohanprasad A., 1. (2006). Catalytic conversion of glycerol and sugar alcohols to value-added products. (Doctoral Dissertation). University of Missouri – Columbia. Retrieved from https://doi.org/10.32469/10355/4331

Chicago Manual of Style (16^th Edition):

Dasari, Mohanprasad A., 1979-. “Catalytic conversion of glycerol and sugar alcohols to value-added products.” 2006. Doctoral Dissertation, University of Missouri – Columbia. Accessed March 06, 2021. https://doi.org/10.32469/10355/4331.

MLA Handbook (7^th Edition):

Dasari, Mohanprasad A., 1979-. “Catalytic conversion of glycerol and sugar alcohols to value-added products.” 2006. Web. 06 Mar 2021.

Vancouver:

Dasari, Mohanprasad A. 1. Catalytic conversion of glycerol and sugar alcohols to value-added products. [Internet] [Doctoral dissertation]. University of Missouri – Columbia; 2006. [cited 2021 Mar 06]. Available from: https://doi.org/10.32469/10355/4331.

Council of Science Editors:

Dasari, Mohanprasad A. 1. Catalytic conversion of glycerol and sugar alcohols to value-added products. [Doctoral Dissertation]. University of Missouri – Columbia; 2006. Available from: https://doi.org/10.32469/10355/4331

University of Toronto

24. Pandit, Aditya Vikram. On the Effectiveness and Challenges of Electrosynthesis Strategies in Escherichia coli.

Degree: PhD, 2017, University of Toronto

URL: http://hdl.handle.net/1807/98810

►

Conventional bioprocesses that aim to convert CO2 to fuels and chemicals do so through a supply chain that begins with agricultural products such as corn,… (more)

▼

Conventional bioprocesses that aim to convert CO2 to fuels and chemicals do so through a supply chain that begins with agricultural products such as corn, intermediaries like dextrose, and eventually produce chemicals by fermentation. However, it has long been desired that bioprocesses be established to convert CO2 point source emissions to chemicals. Fundamentally, this is a thermodynamics problem since the use of CO2 as a feedstock requires an efficient mechanism to deliver energy to produce chemicals. The focus of this work is to examine several strategies for microbial electrosynthesis, the delivery of electrical energy to microbial cell factories, for producing chemicals. The study encompasses four areas type of microbial electrosynthesis and the results are summarized here: 1) Experimental work was performed to evaluate the affect of neutral red mediated charge transfer in mutant strains of Escherichia coli for the purpose of producing succinic acid. The results of this task showed wild-type cells exhibited the greatest molar increase in succinate yield with an 89% increase while an ldhA deficient strain showed 40% increase. The lack of direct charge transfer was implicated as the cause since an electron balance was not able to account for an increase in succinate. 2) We explored the use of mediators such has formate that can be generated from carbon dioxide and renewable electricity as a carbon source for cell growth and chemical production. An auxotrophic strategy was employed to engineer formate assimilation, and growth rate on formate as a C1 donor for folate was determined to be 0.33 h-1. This was 78% of the wild-type strain. 3) We developed a framework for analyzing how metabolic pathways can be efficiently engineered into microbes to produce chemicals. This orthogonality framework showed ethylene glycol to be a highly promising substrate for electrosynthesis applications. 4) Finally, a bioprocess for the conversion of ethylene glycol to glycolic acid was characterized and its suitability to replace glucose as a feedstock was examined. The maximum glycolate titres for the best performing conditions reached 10.6 g/L. The highest substrate uptake rate for ethylene glycol was determined to be ca. 5 mmol/gDW-h.

2019-12-19 00:00:00

Advisors/Committee Members: Mahadevan, Radhakrishnan, Chemical Engineering Applied Chemistry.

Subjects/Keywords: Escherichia coli; ethylene glycol; glycolic acid; metabolic engineering; orthogonality; 0202

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APA (6^th Edition):

Pandit, A. V. (2017). On the Effectiveness and Challenges of Electrosynthesis Strategies in Escherichia coli. (Doctoral Dissertation). University of Toronto. Retrieved from http://hdl.handle.net/1807/98810

Chicago Manual of Style (16^th Edition):

Pandit, Aditya Vikram. “On the Effectiveness and Challenges of Electrosynthesis Strategies in Escherichia coli.” 2017. Doctoral Dissertation, University of Toronto. Accessed March 06, 2021. http://hdl.handle.net/1807/98810.

MLA Handbook (7^th Edition):

Pandit, Aditya Vikram. “On the Effectiveness and Challenges of Electrosynthesis Strategies in Escherichia coli.” 2017. Web. 06 Mar 2021.

Vancouver:

Pandit AV. On the Effectiveness and Challenges of Electrosynthesis Strategies in Escherichia coli. [Internet] [Doctoral dissertation]. University of Toronto; 2017. [cited 2021 Mar 06]. Available from: http://hdl.handle.net/1807/98810.

Council of Science Editors:

Pandit AV. On the Effectiveness and Challenges of Electrosynthesis Strategies in Escherichia coli. [Doctoral Dissertation]. University of Toronto; 2017. Available from: http://hdl.handle.net/1807/98810

University of Toronto

25. Alvares, Rohan. 13C PEG as an In Vivo Macromolecular Probe for MRI and Biophysical Studies of Detergent-Peptide and Detergent-Detergent Interactions using NMR.

Degree: PhD, 2015, University of Toronto

URL: http://hdl.handle.net/1807/77748

►

In the first part of this thesis, a new platform technology is demonstrated for the direct in vivo observation and quantification of macromolecular constituents, such… (more)

Subjects/Keywords: HMQC; molecular imaging; MRI; PEG; poly(ethylene glycol); quantitative; 0485

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APA (6^th Edition):

Alvares, R. (2015). 13C PEG as an In Vivo Macromolecular Probe for MRI and Biophysical Studies of Detergent-Peptide and Detergent-Detergent Interactions using NMR. (Doctoral Dissertation). University of Toronto. Retrieved from http://hdl.handle.net/1807/77748

Chicago Manual of Style (16^th Edition):

Alvares, Rohan. “13C PEG as an In Vivo Macromolecular Probe for MRI and Biophysical Studies of Detergent-Peptide and Detergent-Detergent Interactions using NMR.” 2015. Doctoral Dissertation, University of Toronto. Accessed March 06, 2021. http://hdl.handle.net/1807/77748.

MLA Handbook (7^th Edition):

Alvares, Rohan. “13C PEG as an In Vivo Macromolecular Probe for MRI and Biophysical Studies of Detergent-Peptide and Detergent-Detergent Interactions using NMR.” 2015. Web. 06 Mar 2021.

Vancouver:

Alvares R. 13C PEG as an In Vivo Macromolecular Probe for MRI and Biophysical Studies of Detergent-Peptide and Detergent-Detergent Interactions using NMR. [Internet] [Doctoral dissertation]. University of Toronto; 2015. [cited 2021 Mar 06]. Available from: http://hdl.handle.net/1807/77748.

Council of Science Editors:

Alvares R. 13C PEG as an In Vivo Macromolecular Probe for MRI and Biophysical Studies of Detergent-Peptide and Detergent-Detergent Interactions using NMR. [Doctoral Dissertation]. University of Toronto; 2015. Available from: http://hdl.handle.net/1807/77748

University of Melbourne

26. OZCELIK, BERKAY. Novel biocompatible and biodegradable poly(ethylene glycol)- based scaffolds for soft tissue engineering.

Degree: 2013, University of Melbourne

URL: http://hdl.handle.net/11343/38258

► The development of new three-dimensional (3D) biocompatible constructs with improved properties for tissue regeneration is central to advances in the field of tissue engineering. Materials… (more)

▼ The development of new three-dimensional (3D) biocompatible constructs with improved properties for tissue regeneration is central to advances in the field of tissue engineering. Materials of natural and synthetic origin have been widely investigated for the production of tissue engineering scaffolds via various fabrication methods. Continuing research aims to fabricate scaffolds that possess the important properties of biodegradability, biocompatibility, mechanical integrity, and minimal immunogenicity. Achieving this objective is generally quite difficult since these properties are often dependant on each other and tailoring one property often compromises the other. In this research, we have employed novel synthetic approaches utilising epoxy/amine and acid chloride/alcohol chemistries to prepare poly(ethylene glycol) (PEG)-based scaffolds that are biocompatible and biodegradable, and possess excellent mechanical integrities, making them suitable for various soft-tissue engineering applications. Initially ultrathin Chitosan-PEG hydrogel films (CPHFs) were prepared using epoxy-amine chemistry via diepoxy functionalised PEG, chitosan amines and the co-cross-linker cystamine. The resultant films were very robust and possessed desirable biocompatible and biodegradable properties while supporting the attachment and proliferation of corneal endothelial cells (CECs). To eliminate the issues associated with the use of naturally sourced polymers, we were able to subsequently develop fully synthetic 50 μm thin PEG hydrogel films (PHFs). Acid chloride/alcohol chemistry, together with a facile fabrication method was utilised to produce the PHFs. PHFs were found to possess excellent tensile properties and promoted the in vitro attachment and proliferation of corneal endothelial cells with natural morphologies. In vitro degradation and cytotoxicity studies demonstrated the biodegradable and non-toxic characteristics. In an in vivo ovine model, the hydrogel films adhered naturally onto the interior corneal surface while displaying neither toxicity nor immunogenicity. The PHFs did not hinder the function of the native corneal endothelium, demonstrating their suitability for implantation. To further exploit acid chloride/alcohol chemistry, 3D porous PEG sponges and scaffolds were produced via novel gas foaming, and salt-templating techniques respectively. The rapid exothermic reaction and the HCl gas production results in the formation of highly porous polyester PEG sponges (PPSs), while a salt template was utilised to control pore sizes to produce the hydrogel scaffolds (SPHs). Both PPSs and SPHs possessed excellent mechanical integrities and demonstrated biodegradability and minimal toxicity in vitro. In vivo studies revealed complete infiltration of PPSs and SPHs with vascular tissue within 8 weeks. The porous scaffolds have minimal immunogenicity, and non-toxicity as demonstrated by an in vivo…

Subjects/Keywords: biomaterials; biodegradable; biocompatible; poly(ethylene glycol); tissue engineering; cornea; hydrogel

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

OZCELIK, B. (2013). Novel biocompatible and biodegradable poly(ethylene glycol)- based scaffolds for soft tissue engineering. (Doctoral Dissertation). University of Melbourne. Retrieved from http://hdl.handle.net/11343/38258

Chicago Manual of Style (16^th Edition):

OZCELIK, BERKAY. “Novel biocompatible and biodegradable poly(ethylene glycol)- based scaffolds for soft tissue engineering.” 2013. Doctoral Dissertation, University of Melbourne. Accessed March 06, 2021. http://hdl.handle.net/11343/38258.

MLA Handbook (7^th Edition):

OZCELIK, BERKAY. “Novel biocompatible and biodegradable poly(ethylene glycol)- based scaffolds for soft tissue engineering.” 2013. Web. 06 Mar 2021.

Vancouver:

OZCELIK B. Novel biocompatible and biodegradable poly(ethylene glycol)- based scaffolds for soft tissue engineering. [Internet] [Doctoral dissertation]. University of Melbourne; 2013. [cited 2021 Mar 06]. Available from: http://hdl.handle.net/11343/38258.

Council of Science Editors:

OZCELIK B. Novel biocompatible and biodegradable poly(ethylene glycol)- based scaffolds for soft tissue engineering. [Doctoral Dissertation]. University of Melbourne; 2013. Available from: http://hdl.handle.net/11343/38258

Washington University in St. Louis

27. Smith, Amanda Walker. Engineering Poly(ethylene glycol) Materials to Promote Cardiogenesis.

Degree: PhD, Biomedical Engineering, 2013, Washington University in St. Louis

URL: https://openscholarship.wustl.edu/eng_etds/224

► Heart failure is one of the leading causes of death worldwide, and the current costs of treatment put a significant economic burden on our… (more)

▼ Heart failure is one of the leading causes of death worldwide, and the current costs of treatment put a significant economic burden on our societies. After an infarction, fibrotic tissue begins to form as part of the heart failure cascade. Current options to slow this process include a wide range of pharmaceutical agents, and ultimately the patient may require a heart transplant. Innovative treatment approaches are needed to bring down costs and improve quality of life. The possibility of regenerating or replacing damaged tissue with healthy cardiomyocytes is generating considerable excitement, but there are still many obstacles to overcome. First, while cell injections into the myocardium have demonstrated slight improvements in cardiac function, the actual engraftment of transplanted cells is very low. It is anticipated that improving engraftment will boost outcomes. Second, cellular differentiation and reprogramming protocols have not yet produced cells that are identical to adult cardiomyocytes, and immunogenicity continues to be a problem despite the advent of autologously derived induced pluripotent stem cells. This dissertation will explore biomaterials approaches to addressing these two obstacles. Tissue engineering scaffolds may improve cell engraftment by providing bioactive factors, preventing cell anoikis, and reducing cell washout by blood flow. Poly(ethylene glycol) (PEG) is often used as a coating to reduce implant rejection because it is highly resistant to protein adsorption. Because fibrosis of a material in contact with the myocardium could cause arrhythmias, PEG materials are highly relevant for cardiac tissue engineering applications. In Chapter 2, we describe a novel method for crosslinking PEG microspheres around cells to form a scaffold for tissue engineering. We then demonstrate that HL-1 cardiomyocyte viability and phenotype are retained throughout the fabrication process and during the first 7 weeks of culture. In the third chapter of the dissertation, we demonstrate that the use of PEG cell culture substrates can improve efficiency of direct reprogramming from fibroblasts to cardiomyocytes for cell transplantation. Standard tissue culture plastic adsorbs proteins from the cell media, increasing experimental variability via non-specific signaling. Because of its protein resistant properties, PEG provides cells with highly specific signals. In addition to improving the efficiency, we found that presentation of RGD peptides stimulated proliferation during reprogramming. Combined, the improvements enabled us to approximately double the number of cardiomyocytes produced by the protocol. In Chapter 4, we explore the effects of 3D culture on the direct reprogramming protocol described in Chapter 3. We demonstrate that the variables involved in 3D culture, including scaffold material, diffusion, cellular remodeling, and scaffold topography, have significant effects on reprogramming efficiency. This chapter provides the groundwork for future studies… Advisors/Committee Members: Donald Elbert, Igor Efimov, Guy Genin, Robert Mecham, Jeanne Nerbonne, Shelly Sakiyama-Elbert.

Subjects/Keywords: biomaterials; cardiac tissue engineering; poly(ethylene glycol); scaffold; stem cells; Engineering

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Smith, A. W. (2013). Engineering Poly(ethylene glycol) Materials to Promote Cardiogenesis. (Doctoral Dissertation). Washington University in St. Louis. Retrieved from https://openscholarship.wustl.edu/eng_etds/224

Chicago Manual of Style (16^th Edition):

Smith, Amanda Walker. “Engineering Poly(ethylene glycol) Materials to Promote Cardiogenesis.” 2013. Doctoral Dissertation, Washington University in St. Louis. Accessed March 06, 2021. https://openscholarship.wustl.edu/eng_etds/224.

MLA Handbook (7^th Edition):

Smith, Amanda Walker. “Engineering Poly(ethylene glycol) Materials to Promote Cardiogenesis.” 2013. Web. 06 Mar 2021.

Vancouver:

Smith AW. Engineering Poly(ethylene glycol) Materials to Promote Cardiogenesis. [Internet] [Doctoral dissertation]. Washington University in St. Louis; 2013. [cited 2021 Mar 06]. Available from: https://openscholarship.wustl.edu/eng_etds/224.

Council of Science Editors:

Smith AW. Engineering Poly(ethylene glycol) Materials to Promote Cardiogenesis. [Doctoral Dissertation]. Washington University in St. Louis; 2013. Available from: https://openscholarship.wustl.edu/eng_etds/224

University of Melbourne

28. Halim, Andri. Soft polymeric nanoparticles as additives for CO2 separation membranes.

Degree: 2014, University of Melbourne

URL: http://hdl.handle.net/11343/38663

► The use of polymeric membranes for gas separation has experienced a major expansion in the past few decades with current applications which include the separation… (more)

▼ The use of polymeric membranes for gas separation has experienced a major expansion in the past few decades with current applications which include the separation of CO2 from flue gas. Various approaches have been explored to fabricate membranes with superior separation performance that can exceed the current upper performance limit. These include the incorporation of hard inorganic nanoparticles into polymers to form mixed-matrix membranes (MMMs). The performance of MMMs can be further enhanced if they can be fabricated into asymmetric morphology. The fabrication of asymmetric membranes, in the form of a thin film composite (TFC) membrane, is more commercially viable due to the increased flux and reduced consumption of expensive nanoparticles. TFC membranes are typically composed of a porous support coated with a highly permeable gutter layer, which is in turn coated with a thin active layer. However, the development of effective asymmetric MMMs has been limited. This is due to the difficulty in fabricating nanoparticles in a size that does not exceed the thickness of the active layer and in avoiding defects in the resulting composite structure. The fabrication of next generation mixed-matrix gas separation membranes is also hampered by the need to ensure a defect-free polymer/inorganic particle interface. A similar approach can be applied to the addition of soft polymeric nanoparticles into a selective polymer matrix. In this case, the problem of defects occurring between the particle and the matrix can be avoided through the engineering of particles that are compatible with the polymer matrix. Hence, this thesis aims to synthesize novel soft polymeric nanoparticles with well-defined architectures and utilize these as additives to be incorporated into the thin active layer of TFC membranes. The requirements for these nanoparticles include (a) a soft and CO2 permeable core and (b) a corona which is compatible with the polymer matrix. The best candidate nanoparticles are then blended with a selective polymer matrix to form the active layer of TFC membranes, which are tested for their CO2 separation from N2. The size of the soft polymeric nanoparticles are significantly smaller than the thickness of the active layer and overcome the problem of blending larger inorganic nanoparticles to form asymmetric MMMs. The first soft polymeric nanoparticles studied were based on triblock copolymers containing polyimide (PI) and poly(dimethylsiloxane) (PDMS). Well-defined difunctional PI was initially prepared via step-growth polymerization. Subsequently, PI was functionalized and chain extended with different molar ratios of PDMS-monomethacrylate (PDMS-MA) via atom transfer radical polymerization (ATRP) to form a series of triblock copolymers. Self-assembly of triblock copolymers in a selective solvent for PI, followed by cross-linking via hydrogen…

Subjects/Keywords: membrane; polymer; nanoparticles; self-assembly; polyimide; poly(ethylene glycol); poly(dimethylsiloxane)

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Halim, A. (2014). Soft polymeric nanoparticles as additives for CO2 separation membranes. (Doctoral Dissertation). University of Melbourne. Retrieved from http://hdl.handle.net/11343/38663

Chicago Manual of Style (16^th Edition):

Halim, Andri. “Soft polymeric nanoparticles as additives for CO2 separation membranes.” 2014. Doctoral Dissertation, University of Melbourne. Accessed March 06, 2021. http://hdl.handle.net/11343/38663.

MLA Handbook (7^th Edition):

Halim, Andri. “Soft polymeric nanoparticles as additives for CO2 separation membranes.” 2014. Web. 06 Mar 2021.

Vancouver:

Halim A. Soft polymeric nanoparticles as additives for CO2 separation membranes. [Internet] [Doctoral dissertation]. University of Melbourne; 2014. [cited 2021 Mar 06]. Available from: http://hdl.handle.net/11343/38663.

Council of Science Editors:

Halim A. Soft polymeric nanoparticles as additives for CO2 separation membranes. [Doctoral Dissertation]. University of Melbourne; 2014. Available from: http://hdl.handle.net/11343/38663

University of Louisville

29. Phillips, Jeremy E. Surface bound PEG-RGDS on PEG-DA hydrogels and its effects on RPE cell morphology and differentiation.

Degree: M. Eng., 2013, University of Louisville

URL: 10.18297/etd/1132 ; https://ir.library.louisville.edu/etd/1132

► Age related macular Degeneration is a retinal condition resulting in visual impairment and central vision loss caused by dysfunction of the Bruch’s membrane and the… (more)

Subjects/Keywords: Poly (ethylene glycol); RGDS; Macular degeneration; retinal pigmented epithelium

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Phillips, J. E. (2013). Surface bound PEG-RGDS on PEG-DA hydrogels and its effects on RPE cell morphology and differentiation. (Masters Thesis). University of Louisville. Retrieved from 10.18297/etd/1132 ; https://ir.library.louisville.edu/etd/1132

Chicago Manual of Style (16^th Edition):

Phillips, Jeremy E. “Surface bound PEG-RGDS on PEG-DA hydrogels and its effects on RPE cell morphology and differentiation.” 2013. Masters Thesis, University of Louisville. Accessed March 06, 2021. 10.18297/etd/1132 ; https://ir.library.louisville.edu/etd/1132.

MLA Handbook (7^th Edition):

Phillips, Jeremy E. “Surface bound PEG-RGDS on PEG-DA hydrogels and its effects on RPE cell morphology and differentiation.” 2013. Web. 06 Mar 2021.

Vancouver:

Phillips JE. Surface bound PEG-RGDS on PEG-DA hydrogels and its effects on RPE cell morphology and differentiation. [Internet] [Masters thesis]. University of Louisville; 2013. [cited 2021 Mar 06]. Available from: 10.18297/etd/1132 ; https://ir.library.louisville.edu/etd/1132.

Council of Science Editors:

Phillips JE. Surface bound PEG-RGDS on PEG-DA hydrogels and its effects on RPE cell morphology and differentiation. [Masters Thesis]. University of Louisville; 2013. Available from: 10.18297/etd/1132 ; https://ir.library.louisville.edu/etd/1132

The Ohio State University

30. Painter, Robert Blair. The utilization of ethylene glycol by Pseudomonas.

Degree: PhD, Graduate School, 1955, The Ohio State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1485795295565297

Subjects/Keywords: Biology; Ethylene glycol; Pseudomonas

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Painter, R. B. (1955). The utilization of ethylene glycol by Pseudomonas. (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1485795295565297

Chicago Manual of Style (16^th Edition):

Painter, Robert Blair. “The utilization of ethylene glycol by Pseudomonas.” 1955. Doctoral Dissertation, The Ohio State University. Accessed March 06, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=osu1485795295565297.

MLA Handbook (7^th Edition):

Painter, Robert Blair. “The utilization of ethylene glycol by Pseudomonas.” 1955. Web. 06 Mar 2021.

Vancouver:

Painter RB. The utilization of ethylene glycol by Pseudomonas. [Internet] [Doctoral dissertation]. The Ohio State University; 1955. [cited 2021 Mar 06]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1485795295565297.

Council of Science Editors:

Painter RB. The utilization of ethylene glycol by Pseudomonas. [Doctoral Dissertation]. The Ohio State University; 1955. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1485795295565297

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Open Access Theses and Dissertations