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1. Jackson, Erin Elizabeth. Novel Intraosseous Device Performance and Longevity in a Goat Model (Capra hircus).

Degree: MS, Laboratory Animal Medicine, 2012, Texas A&M University

Two studies were performed to assess the function and longevity of a novel intraosseous (IO) catheter device. For the initial study, nine animals were assigned to three study groups. The first group received a 25 mm intraosseous device within the proximal humerus, the second group within the proximal tibia, and standard jugular catheters were placed in the final control group. Serial aerobic and anaerobic blood cultures were collected from jugular veins at day zero, then every third day while devices remained in use. Radiographs were obtained immediately after placement and again after removal of all IO devices. Goats were observed for overall clinical condition and lameness associated with catheter sites, and catheters were evaluated for patency and proper positioning. IO devices in the tibia remained in for less time than those in the humerus. Blood cultures in this study showed growth of Bacillus, Staphylococcus, and one colony within the genera Brachyacterium or novel Dermabacteraceae. Catheters also showed growth of Bacillus, as well as a single colony of Micromonospora chalcea. No animals in either IO group exhibited radiographic evidence of resulting damage or structural change within surrounding bone. In study two, eighteen goats were assigned to two study groups (25 mm intraosseous device within the wing of the ilium, or 45 mm catheter in the proximal humerus). Blood for serial aerobic and anaerobic blood cultures and CBC were collected from jugular veins at day zero, then every second day thereafter while devices remained in use. All clinical monitoring and removal criteria were identical to study one. Catheters in the ilium remained in significantly less time than those in the humerus. Several animals in the proximal humerus group demonstrated moderate lameness following removal. One goat developed an abscess near the insertion site and showed radiographic evidence of periosteal bone growth. Serial cultures showed growth of Bacillus, Streptococcus, Staphylococcus, and Enterococcus. Bloodwork indicated mild elevations of white blood cells from baseline in some cases. Our study indicated that catheters may remain safely in place for greater than 24 hours, but that animals should be closely monitored for negative side-effects for several days during the post-removal period. Advisors/Committee Members: Snowden, Karen (advisor), Gresham, Vincent (committee member), Mouneimne, Barhoumi (committee member).

Subjects/Keywords: Intraosseous catheter; EZ-IO®

…multiple anatomic sites with or without the use of local anesthetics. The EZ-IO® comes in several… …The EZ-IO® has recently become available for use in veterinary medicine. We feel that in… …then placed through the skin and bone using the EZ-IO® high- 4 powered drill. Tibial… …insertion point. The cannulas were then placed through the skin and bone using the EZ-IO… …force by the animal’s body weight during normal activity, or in a recumbent animal. The EZ-IO… 

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Jackson, E. E. (2012). Novel Intraosseous Device Performance and Longevity in a Goat Model (Capra hircus). (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2010-12-8589

Chicago Manual of Style (16th Edition):

Jackson, Erin Elizabeth. “Novel Intraosseous Device Performance and Longevity in a Goat Model (Capra hircus).” 2012. Masters Thesis, Texas A&M University. Accessed February 25, 2021. http://hdl.handle.net/1969.1/ETD-TAMU-2010-12-8589.

MLA Handbook (7th Edition):

Jackson, Erin Elizabeth. “Novel Intraosseous Device Performance and Longevity in a Goat Model (Capra hircus).” 2012. Web. 25 Feb 2021.

Vancouver:

Jackson EE. Novel Intraosseous Device Performance and Longevity in a Goat Model (Capra hircus). [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Feb 25]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2010-12-8589.

Council of Science Editors:

Jackson EE. Novel Intraosseous Device Performance and Longevity in a Goat Model (Capra hircus). [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2010-12-8589

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