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You searched for subject:(Drug repurposing). Showing records 1 – 30 of 33 total matches.

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University of Utah

1. Gibson, Christopher C. Identification of novel treatments for a hereditary stroke disorder using quantitative phenotypic fingerprinting.

Degree: PhD, Bioengineering, 2014, University of Utah

 Destabilization of the endothelial monolayer lining blood vessels has profound consequences onorganismal homeostasis. Vascular instability plays a well-known role in the pathophysiology of diseasesfrom sepsis… (more)

Subjects/Keywords: Drug discovery; Drug repurposing; Endothelium; High-content; Screening; Stroke

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APA (6th Edition):

Gibson, C. C. (2014). Identification of novel treatments for a hereditary stroke disorder using quantitative phenotypic fingerprinting. (Doctoral Dissertation). University of Utah. Retrieved from http://content.lib.utah.edu/cdm/singleitem/collection/etd3/id/3501/rec/1282

Chicago Manual of Style (16th Edition):

Gibson, Christopher C. “Identification of novel treatments for a hereditary stroke disorder using quantitative phenotypic fingerprinting.” 2014. Doctoral Dissertation, University of Utah. Accessed January 22, 2020. http://content.lib.utah.edu/cdm/singleitem/collection/etd3/id/3501/rec/1282.

MLA Handbook (7th Edition):

Gibson, Christopher C. “Identification of novel treatments for a hereditary stroke disorder using quantitative phenotypic fingerprinting.” 2014. Web. 22 Jan 2020.

Vancouver:

Gibson CC. Identification of novel treatments for a hereditary stroke disorder using quantitative phenotypic fingerprinting. [Internet] [Doctoral dissertation]. University of Utah; 2014. [cited 2020 Jan 22]. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd3/id/3501/rec/1282.

Council of Science Editors:

Gibson CC. Identification of novel treatments for a hereditary stroke disorder using quantitative phenotypic fingerprinting. [Doctoral Dissertation]. University of Utah; 2014. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd3/id/3501/rec/1282


University of Manitoba

2. Blankstein, Anna R. Siramesine and lapatinib induce synergic cell death via a ferroptotic mechanism in lung adenocarcinoma and glioblastoma cells.

Degree: Biochemistry and Medical Genetics, 2017, University of Manitoba

 In cancer cells, the most common forms of cell death are often actively inhibited, contributing to the development of drug resistance. Identifying and exploiting alternative… (more)

Subjects/Keywords: Cell death; Ferroptosis; Glioblastoma; Lung adenocarcinoma; Drug synergy; Drug repurposing

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APA (6th Edition):

Blankstein, A. R. (2017). Siramesine and lapatinib induce synergic cell death via a ferroptotic mechanism in lung adenocarcinoma and glioblastoma cells. (Masters Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/32404

Chicago Manual of Style (16th Edition):

Blankstein, Anna R. “Siramesine and lapatinib induce synergic cell death via a ferroptotic mechanism in lung adenocarcinoma and glioblastoma cells.” 2017. Masters Thesis, University of Manitoba. Accessed January 22, 2020. http://hdl.handle.net/1993/32404.

MLA Handbook (7th Edition):

Blankstein, Anna R. “Siramesine and lapatinib induce synergic cell death via a ferroptotic mechanism in lung adenocarcinoma and glioblastoma cells.” 2017. Web. 22 Jan 2020.

Vancouver:

Blankstein AR. Siramesine and lapatinib induce synergic cell death via a ferroptotic mechanism in lung adenocarcinoma and glioblastoma cells. [Internet] [Masters thesis]. University of Manitoba; 2017. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/1993/32404.

Council of Science Editors:

Blankstein AR. Siramesine and lapatinib induce synergic cell death via a ferroptotic mechanism in lung adenocarcinoma and glioblastoma cells. [Masters Thesis]. University of Manitoba; 2017. Available from: http://hdl.handle.net/1993/32404


Virginia Commonwealth University

3. Wang, Chen. High-throughput prediction and analysis of drug-protein interactions in the druggable human proteome.

Degree: PhD, Computer Science, 2018, Virginia Commonwealth University

  Drugs exert their (therapeutic) effects via molecular-level interactions with proteins and other biomolecules. Computational prediction of drug-protein interactions plays a significant role in the… (more)

Subjects/Keywords: drug-protein interactions; computational prediction; drug target database; drug repurposing; drug side-effects; Bioinformatics

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APA (6th Edition):

Wang, C. (2018). High-throughput prediction and analysis of drug-protein interactions in the druggable human proteome. (Doctoral Dissertation). Virginia Commonwealth University. Retrieved from https://scholarscompass.vcu.edu/etd/5509

Chicago Manual of Style (16th Edition):

Wang, Chen. “High-throughput prediction and analysis of drug-protein interactions in the druggable human proteome.” 2018. Doctoral Dissertation, Virginia Commonwealth University. Accessed January 22, 2020. https://scholarscompass.vcu.edu/etd/5509.

MLA Handbook (7th Edition):

Wang, Chen. “High-throughput prediction and analysis of drug-protein interactions in the druggable human proteome.” 2018. Web. 22 Jan 2020.

Vancouver:

Wang C. High-throughput prediction and analysis of drug-protein interactions in the druggable human proteome. [Internet] [Doctoral dissertation]. Virginia Commonwealth University; 2018. [cited 2020 Jan 22]. Available from: https://scholarscompass.vcu.edu/etd/5509.

Council of Science Editors:

Wang C. High-throughput prediction and analysis of drug-protein interactions in the druggable human proteome. [Doctoral Dissertation]. Virginia Commonwealth University; 2018. Available from: https://scholarscompass.vcu.edu/etd/5509


University of Rochester

4. Butts, Arielle Marie (1989 - ). Repurposing triphenylethylene estrogen receptor antagonists as anticryptococcal agents.

Degree: PhD, 2014, University of Rochester

 Cryptococcus neoformans is an opportunistic human fungal pathogen that is capable of causing life-threatening infections. These infections generally occur in individuals with compromised immunity such… (more)

Subjects/Keywords: Antifungal; Cryptococcus; Drug discovery; Mode of action; Repurposing

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APA (6th Edition):

Butts, A. M. (. -. ). (2014). Repurposing triphenylethylene estrogen receptor antagonists as anticryptococcal agents. (Doctoral Dissertation). University of Rochester. Retrieved from http://hdl.handle.net/1802/28300

Chicago Manual of Style (16th Edition):

Butts, Arielle Marie (1989 - ). “Repurposing triphenylethylene estrogen receptor antagonists as anticryptococcal agents.” 2014. Doctoral Dissertation, University of Rochester. Accessed January 22, 2020. http://hdl.handle.net/1802/28300.

MLA Handbook (7th Edition):

Butts, Arielle Marie (1989 - ). “Repurposing triphenylethylene estrogen receptor antagonists as anticryptococcal agents.” 2014. Web. 22 Jan 2020.

Vancouver:

Butts AM(-). Repurposing triphenylethylene estrogen receptor antagonists as anticryptococcal agents. [Internet] [Doctoral dissertation]. University of Rochester; 2014. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/1802/28300.

Council of Science Editors:

Butts AM(-). Repurposing triphenylethylene estrogen receptor antagonists as anticryptococcal agents. [Doctoral Dissertation]. University of Rochester; 2014. Available from: http://hdl.handle.net/1802/28300


University of Toronto

5. Yun, Junghwa. Validation and Mechanistic Studies of Gluconeogenesis Regulators Identified from Zebrafish Chemical Genetic Screens.

Degree: 2017, University of Toronto

Phosphoenolypyruvate carboxykinase (PEPCK) is the rate limiting enzyme in hepatic gluconeogenesis, which produces glucose from pyruvate to maintain circulating glucose level according to the bodyâ… (more)

Subjects/Keywords: Diabetes; Drug repurposing; Gluconeogenesis; Pck1; Pyruvate tolerance test; Zebrafish; 0719

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APA (6th Edition):

Yun, J. (2017). Validation and Mechanistic Studies of Gluconeogenesis Regulators Identified from Zebrafish Chemical Genetic Screens. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/97184

Chicago Manual of Style (16th Edition):

Yun, Junghwa. “Validation and Mechanistic Studies of Gluconeogenesis Regulators Identified from Zebrafish Chemical Genetic Screens.” 2017. Masters Thesis, University of Toronto. Accessed January 22, 2020. http://hdl.handle.net/1807/97184.

MLA Handbook (7th Edition):

Yun, Junghwa. “Validation and Mechanistic Studies of Gluconeogenesis Regulators Identified from Zebrafish Chemical Genetic Screens.” 2017. Web. 22 Jan 2020.

Vancouver:

Yun J. Validation and Mechanistic Studies of Gluconeogenesis Regulators Identified from Zebrafish Chemical Genetic Screens. [Internet] [Masters thesis]. University of Toronto; 2017. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/1807/97184.

Council of Science Editors:

Yun J. Validation and Mechanistic Studies of Gluconeogenesis Regulators Identified from Zebrafish Chemical Genetic Screens. [Masters Thesis]. University of Toronto; 2017. Available from: http://hdl.handle.net/1807/97184


Texas A&M University

6. Sundararajan Venkatasubramani, Priyadharshini. Bayesian Network Modeling and Inference in Plant Gene Networks And Analysis of Sequencing and Imaging Data.

Degree: PhD, Electrical Engineering, 2017, Texas A&M University

 Scientific and technological advancements over the years have made curing, preventing or managing all diseases, a goal that seems to be within reach. The approach… (more)

Subjects/Keywords: plant pathogen interactions; metformin; RNA sequencing; drug repurposing; bayesian networks

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APA (6th Edition):

Sundararajan Venkatasubramani, P. (2017). Bayesian Network Modeling and Inference in Plant Gene Networks And Analysis of Sequencing and Imaging Data. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/165919

Chicago Manual of Style (16th Edition):

Sundararajan Venkatasubramani, Priyadharshini. “Bayesian Network Modeling and Inference in Plant Gene Networks And Analysis of Sequencing and Imaging Data.” 2017. Doctoral Dissertation, Texas A&M University. Accessed January 22, 2020. http://hdl.handle.net/1969.1/165919.

MLA Handbook (7th Edition):

Sundararajan Venkatasubramani, Priyadharshini. “Bayesian Network Modeling and Inference in Plant Gene Networks And Analysis of Sequencing and Imaging Data.” 2017. Web. 22 Jan 2020.

Vancouver:

Sundararajan Venkatasubramani P. Bayesian Network Modeling and Inference in Plant Gene Networks And Analysis of Sequencing and Imaging Data. [Internet] [Doctoral dissertation]. Texas A&M University; 2017. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/1969.1/165919.

Council of Science Editors:

Sundararajan Venkatasubramani P. Bayesian Network Modeling and Inference in Plant Gene Networks And Analysis of Sequencing and Imaging Data. [Doctoral Dissertation]. Texas A&M University; 2017. Available from: http://hdl.handle.net/1969.1/165919

7. Dai, Yuheng. The Commercilazation of a Noval Antithrombotic Drug.

Degree: MSs, Biology, 2018, Case Western Reserve University School of Graduate Studies

 Thrombotic events are the main cause of morbidity and mortality in developed countries, and continue to be an important focus for new therapeutic research. A… (more)

Subjects/Keywords: Biology; Medicine; Thymidine phosphorylase, platelet, thrombosis, anti-platelet therapy, commercialization, drug repositioning, drug repurposing

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APA (6th Edition):

Dai, Y. (2018). The Commercilazation of a Noval Antithrombotic Drug. (Masters Thesis). Case Western Reserve University School of Graduate Studies. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=case1505303242046038

Chicago Manual of Style (16th Edition):

Dai, Yuheng. “The Commercilazation of a Noval Antithrombotic Drug.” 2018. Masters Thesis, Case Western Reserve University School of Graduate Studies. Accessed January 22, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=case1505303242046038.

MLA Handbook (7th Edition):

Dai, Yuheng. “The Commercilazation of a Noval Antithrombotic Drug.” 2018. Web. 22 Jan 2020.

Vancouver:

Dai Y. The Commercilazation of a Noval Antithrombotic Drug. [Internet] [Masters thesis]. Case Western Reserve University School of Graduate Studies; 2018. [cited 2020 Jan 22]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1505303242046038.

Council of Science Editors:

Dai Y. The Commercilazation of a Noval Antithrombotic Drug. [Masters Thesis]. Case Western Reserve University School of Graduate Studies; 2018. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1505303242046038


Leiden University

8. Frouws, M.A. Renewing clinical applications for commonly used medications in gastrointestinal cancer.

Degree: 2017, Leiden University

This thesis tried to unravel the epidemiological background of the current evidence on the effect of aspirin on gastrointestinal cancer. Advisors/Committee Members: Supervisor: C.J.H. van de Velde Co-Supervisors: G.J. Liefers, J.E.A. Portielje.

Subjects/Keywords: Aspirine; Drug repurposing; Gastrointestinal cancer; Aspirine; Drug repurposing; Gastrointestinal cancer

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APA (6th Edition):

Frouws, M. A. (2017). Renewing clinical applications for commonly used medications in gastrointestinal cancer. (Doctoral Dissertation). Leiden University. Retrieved from http://hdl.handle.net/1887/55950

Chicago Manual of Style (16th Edition):

Frouws, M A. “Renewing clinical applications for commonly used medications in gastrointestinal cancer.” 2017. Doctoral Dissertation, Leiden University. Accessed January 22, 2020. http://hdl.handle.net/1887/55950.

MLA Handbook (7th Edition):

Frouws, M A. “Renewing clinical applications for commonly used medications in gastrointestinal cancer.” 2017. Web. 22 Jan 2020.

Vancouver:

Frouws MA. Renewing clinical applications for commonly used medications in gastrointestinal cancer. [Internet] [Doctoral dissertation]. Leiden University; 2017. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/1887/55950.

Council of Science Editors:

Frouws MA. Renewing clinical applications for commonly used medications in gastrointestinal cancer. [Doctoral Dissertation]. Leiden University; 2017. Available from: http://hdl.handle.net/1887/55950


University of Cincinnati

9. Patchala, Jagadeesh. Data Mining Algorithms for Discovering Patterns in Text Collections.

Degree: PhD, Engineering and Applied Science: Computer Science and Engineering, 2016, University of Cincinnati

 Discovering meta-information from collections of text documents is becoming an important research area due to increasing demands for automated analysis of large text collections. This… (more)

Subjects/Keywords: Computer Science; Authorship Analysis; Biclustering; 3-clusters; Drug repurposing; Text mining; Data mining

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APA (6th Edition):

Patchala, J. (2016). Data Mining Algorithms for Discovering Patterns in Text Collections. (Doctoral Dissertation). University of Cincinnati. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=ucin1458299372

Chicago Manual of Style (16th Edition):

Patchala, Jagadeesh. “Data Mining Algorithms for Discovering Patterns in Text Collections.” 2016. Doctoral Dissertation, University of Cincinnati. Accessed January 22, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1458299372.

MLA Handbook (7th Edition):

Patchala, Jagadeesh. “Data Mining Algorithms for Discovering Patterns in Text Collections.” 2016. Web. 22 Jan 2020.

Vancouver:

Patchala J. Data Mining Algorithms for Discovering Patterns in Text Collections. [Internet] [Doctoral dissertation]. University of Cincinnati; 2016. [cited 2020 Jan 22]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=ucin1458299372.

Council of Science Editors:

Patchala J. Data Mining Algorithms for Discovering Patterns in Text Collections. [Doctoral Dissertation]. University of Cincinnati; 2016. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=ucin1458299372

10. Hadwen, Jeremiah. Repurposing Clinic-Tested Drugs to Treat Rare Neurogenetic Diseases by Transcriptional Modulation .

Degree: 2018, University of Ottawa

 Rare diseases caused by single-gene mutations affect almost one million Canadians. According to the Online Mendelian Inheritance in Man database, ~4,500 rare monogenic diseases have… (more)

Subjects/Keywords: Neurogenetics; Rare diseases; Drug repurposing

…Transcriptional drug repurposing to treat rare neurogenetic diseases 1 Rare monogenic diseases Rare… …view. Drug repurposing Repurposing clinically-tested small molecules and biologics has… …clinical effect, are prime targets for drug repurposing. Compared to new drug development, the… …early instances of drug repurposing occurred serendipitously because of unanticipated side… …effects. As drug repurposing research has gained momentum, more structured and efficient… 

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APA (6th Edition):

Hadwen, J. (2018). Repurposing Clinic-Tested Drugs to Treat Rare Neurogenetic Diseases by Transcriptional Modulation . (Thesis). University of Ottawa. Retrieved from http://hdl.handle.net/10393/37581

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Hadwen, Jeremiah. “Repurposing Clinic-Tested Drugs to Treat Rare Neurogenetic Diseases by Transcriptional Modulation .” 2018. Thesis, University of Ottawa. Accessed January 22, 2020. http://hdl.handle.net/10393/37581.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Hadwen, Jeremiah. “Repurposing Clinic-Tested Drugs to Treat Rare Neurogenetic Diseases by Transcriptional Modulation .” 2018. Web. 22 Jan 2020.

Vancouver:

Hadwen J. Repurposing Clinic-Tested Drugs to Treat Rare Neurogenetic Diseases by Transcriptional Modulation . [Internet] [Thesis]. University of Ottawa; 2018. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/10393/37581.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Hadwen J. Repurposing Clinic-Tested Drugs to Treat Rare Neurogenetic Diseases by Transcriptional Modulation . [Thesis]. University of Ottawa; 2018. Available from: http://hdl.handle.net/10393/37581

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of the Western Cape

11. Omoruyi, Sylvester Ifeanyi. Investigating the anti-cancer activity of novel phenothiazines in glioblastoma .

Degree: 2018, University of the Western Cape

 Glioblastoma multiforme (GBM) remains the most malignant of all primary adult brain tumours. It is a highly invasive and vascularized neoplasm with limited treatment options… (more)

Subjects/Keywords: Drug repurposing; Phenothiazines; Chemotherapy; Anti-cancer agents; Cancer; Brain tumours; Glioblastoma; DNA damage; Apoptosis; Autophagy

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APA (6th Edition):

Omoruyi, S. I. (2018). Investigating the anti-cancer activity of novel phenothiazines in glioblastoma . (Thesis). University of the Western Cape. Retrieved from http://hdl.handle.net/11394/6329

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Omoruyi, Sylvester Ifeanyi. “Investigating the anti-cancer activity of novel phenothiazines in glioblastoma .” 2018. Thesis, University of the Western Cape. Accessed January 22, 2020. http://hdl.handle.net/11394/6329.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Omoruyi, Sylvester Ifeanyi. “Investigating the anti-cancer activity of novel phenothiazines in glioblastoma .” 2018. Web. 22 Jan 2020.

Vancouver:

Omoruyi SI. Investigating the anti-cancer activity of novel phenothiazines in glioblastoma . [Internet] [Thesis]. University of the Western Cape; 2018. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/11394/6329.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Omoruyi SI. Investigating the anti-cancer activity of novel phenothiazines in glioblastoma . [Thesis]. University of the Western Cape; 2018. Available from: http://hdl.handle.net/11394/6329

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

12. ADLER, NIKOLETTA. Development of Novel Anti-Trypanosomal Compounds via Computational, In Vitro and In Vivo Methods.

Degree: School of Biochemistry & Immunology. Discipline of Biochemistry, 2018, Trinity College Dublin

 Human African Trypanosomiasis is a neglected parasitic disease caused by Trypanosoma brucei, which if left untreated eventually leads to coma and death. With no successful… (more)

Subjects/Keywords: anti-trypnosomal; cysteine protease inhibitor; drug repurposing; Fingolimod; S1P; SPK-843; Amphotericin B

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APA (6th Edition):

ADLER, N. (2018). Development of Novel Anti-Trypanosomal Compounds via Computational, In Vitro and In Vivo Methods. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/82830

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

ADLER, NIKOLETTA. “Development of Novel Anti-Trypanosomal Compounds via Computational, In Vitro and In Vivo Methods.” 2018. Thesis, Trinity College Dublin. Accessed January 22, 2020. http://hdl.handle.net/2262/82830.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

ADLER, NIKOLETTA. “Development of Novel Anti-Trypanosomal Compounds via Computational, In Vitro and In Vivo Methods.” 2018. Web. 22 Jan 2020.

Vancouver:

ADLER N. Development of Novel Anti-Trypanosomal Compounds via Computational, In Vitro and In Vivo Methods. [Internet] [Thesis]. Trinity College Dublin; 2018. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/2262/82830.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

ADLER N. Development of Novel Anti-Trypanosomal Compounds via Computational, In Vitro and In Vivo Methods. [Thesis]. Trinity College Dublin; 2018. Available from: http://hdl.handle.net/2262/82830

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Illinois – Urbana-Champaign

13. Ostadhossein, Fatemeh. A next generation theranostic nano-platform for sustained and enhanced inhibition of cancer stem cells.

Degree: MS, Bioengineering, 2015, University of Illinois – Urbana-Champaign

 Primary tumor extermination and conventional chemotherapy are proved to be inefficient in cancer therapy in that they preferentially abolish differentiated cells whilst leaving behind treatment… (more)

Subjects/Keywords: Cancer stem cell; STAT3 inhibition; Drug Delivery; Drug Repurposing; Carbon nanoparticles; Host guest chemistry; Cucurbitruil[6]; Niclosamide

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APA (6th Edition):

Ostadhossein, F. (2015). A next generation theranostic nano-platform for sustained and enhanced inhibition of cancer stem cells. (Thesis). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/89162

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Ostadhossein, Fatemeh. “A next generation theranostic nano-platform for sustained and enhanced inhibition of cancer stem cells.” 2015. Thesis, University of Illinois – Urbana-Champaign. Accessed January 22, 2020. http://hdl.handle.net/2142/89162.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Ostadhossein, Fatemeh. “A next generation theranostic nano-platform for sustained and enhanced inhibition of cancer stem cells.” 2015. Web. 22 Jan 2020.

Vancouver:

Ostadhossein F. A next generation theranostic nano-platform for sustained and enhanced inhibition of cancer stem cells. [Internet] [Thesis]. University of Illinois – Urbana-Champaign; 2015. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/2142/89162.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ostadhossein F. A next generation theranostic nano-platform for sustained and enhanced inhibition of cancer stem cells. [Thesis]. University of Illinois – Urbana-Champaign; 2015. Available from: http://hdl.handle.net/2142/89162

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Purdue University

14. Thangamani, Shankar. Repurposing non-antimicrobial drugs to treat multi-drug resistant bacterial and fungal infections.

Degree: PhD, 2016, Purdue University

  Bacterial and fungal resistance to conventional antimicrobials is a burgeoning global health epidemic that necessitates urgent action. Even more alarming, the development of new… (more)

Subjects/Keywords: Biological sciences; Health and environmental sciences; Antimicrobial resistance; Approved drugs; Bacteria; Drug discovery; Fungi; Repurposing; Immunology and Infectious Disease; Microbiology

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APA (6th Edition):

Thangamani, S. (2016). Repurposing non-antimicrobial drugs to treat multi-drug resistant bacterial and fungal infections. (Doctoral Dissertation). Purdue University. Retrieved from https://docs.lib.purdue.edu/open_access_dissertations/1015

Chicago Manual of Style (16th Edition):

Thangamani, Shankar. “Repurposing non-antimicrobial drugs to treat multi-drug resistant bacterial and fungal infections.” 2016. Doctoral Dissertation, Purdue University. Accessed January 22, 2020. https://docs.lib.purdue.edu/open_access_dissertations/1015.

MLA Handbook (7th Edition):

Thangamani, Shankar. “Repurposing non-antimicrobial drugs to treat multi-drug resistant bacterial and fungal infections.” 2016. Web. 22 Jan 2020.

Vancouver:

Thangamani S. Repurposing non-antimicrobial drugs to treat multi-drug resistant bacterial and fungal infections. [Internet] [Doctoral dissertation]. Purdue University; 2016. [cited 2020 Jan 22]. Available from: https://docs.lib.purdue.edu/open_access_dissertations/1015.

Council of Science Editors:

Thangamani S. Repurposing non-antimicrobial drugs to treat multi-drug resistant bacterial and fungal infections. [Doctoral Dissertation]. Purdue University; 2016. Available from: https://docs.lib.purdue.edu/open_access_dissertations/1015


University of Vienna

15. Gurinova, Jana. Development of a KNIME workflow for the retrieval of associations between orphan diseases and their possible drug repurposing candidates.

Degree: 2018, University of Vienna

 Seltene Erkrankungen betreffen weltweit über 400 Millionen Menschen. Sie werden über ihre Häufigkeit beziehungsweise ihre Seltenheit definiert, und daher zwangsläufig auch über eine geringe Zahl… (more)

Subjects/Keywords: 44.42 Pharmazeutische Chemie; 44.40 Pharmazie, Pharmazeutika; 44.48 Medizinische Genetik; seltene Erkrankungen / KNIME / Workflow / Data-Mining / Neupositionierung; orphan diseases / rare diseases / KNIME / workflow / data mining / drug repurposing / drug repositioning

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Gurinova, J. (2018). Development of a KNIME workflow for the retrieval of associations between orphan diseases and their possible drug repurposing candidates. (Thesis). University of Vienna. Retrieved from http://othes.univie.ac.at/55364/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Gurinova, Jana. “Development of a KNIME workflow for the retrieval of associations between orphan diseases and their possible drug repurposing candidates.” 2018. Thesis, University of Vienna. Accessed January 22, 2020. http://othes.univie.ac.at/55364/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Gurinova, Jana. “Development of a KNIME workflow for the retrieval of associations between orphan diseases and their possible drug repurposing candidates.” 2018. Web. 22 Jan 2020.

Vancouver:

Gurinova J. Development of a KNIME workflow for the retrieval of associations between orphan diseases and their possible drug repurposing candidates. [Internet] [Thesis]. University of Vienna; 2018. [cited 2020 Jan 22]. Available from: http://othes.univie.ac.at/55364/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Gurinova J. Development of a KNIME workflow for the retrieval of associations between orphan diseases and their possible drug repurposing candidates. [Thesis]. University of Vienna; 2018. Available from: http://othes.univie.ac.at/55364/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

16. Dhara, Roopesh. COMPUTATIONAL DRUG REPURPOSING FOR BREAST CANCER SUBTYPES.

Degree: MS, Computer Science, 2019, University of Windsor

 Breast cancer makes up 25 percent of all new cancer diagnoses globally according to the American Cancer Society(ACS). Developing a highly effective drug can be… (more)

Subjects/Keywords: breast cancer; clustering; drug repositioning; drug repurposing; machine learning; pharmacology

…Traditional drug discovery and development process . . . . . . 2 1.1.3 What is drug repurposing… …Drug Repurposing 1 viii 1.6 Thesis Organization… …2 Literature Review 2.1 Existing approaches on drug repurposing… …2.1.1 3 Proposed Methods 3.2 3.3 10 11 A new computational drug repurposing method using… …paradigm: Dr Insight empowers signature free, enhanced drug repurposing… 

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Dhara, R. (2019). COMPUTATIONAL DRUG REPURPOSING FOR BREAST CANCER SUBTYPES. (Masters Thesis). University of Windsor. Retrieved from https://scholar.uwindsor.ca/etd/7696

Chicago Manual of Style (16th Edition):

Dhara, Roopesh. “COMPUTATIONAL DRUG REPURPOSING FOR BREAST CANCER SUBTYPES.” 2019. Masters Thesis, University of Windsor. Accessed January 22, 2020. https://scholar.uwindsor.ca/etd/7696.

MLA Handbook (7th Edition):

Dhara, Roopesh. “COMPUTATIONAL DRUG REPURPOSING FOR BREAST CANCER SUBTYPES.” 2019. Web. 22 Jan 2020.

Vancouver:

Dhara R. COMPUTATIONAL DRUG REPURPOSING FOR BREAST CANCER SUBTYPES. [Internet] [Masters thesis]. University of Windsor; 2019. [cited 2020 Jan 22]. Available from: https://scholar.uwindsor.ca/etd/7696.

Council of Science Editors:

Dhara R. COMPUTATIONAL DRUG REPURPOSING FOR BREAST CANCER SUBTYPES. [Masters Thesis]. University of Windsor; 2019. Available from: https://scholar.uwindsor.ca/etd/7696


University of Michigan

17. Murashov, Mikhail. Pharmaceutical Impact of the Different Ionization States of a Weakly Basic Drug within a Living Organism.

Degree: PhD, Pharmaceutical Sciences, 2019, University of Michigan

 Clofazimine (CFZ), an oral FDA-approved antibiotic for over 40 years, has been used effectively against leprosy and multi-drug resistant tuberculosis (MDR-TB). Due to its atypical… (more)

Subjects/Keywords: ionization states of a weakly basic drug within a living organism; physicochemical parameters of clofazimine; clofazimine drug biocrystals within tissue macrophages; clofazimine-induced skin pigmentation, adverse drug reaction; biomimetic formulation of micronized drug crystals; clofazimine reformulation and repurposing; Pharmacy and Pharmacology; Health Sciences

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APA (6th Edition):

Murashov, M. (2019). Pharmaceutical Impact of the Different Ionization States of a Weakly Basic Drug within a Living Organism. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/149961

Chicago Manual of Style (16th Edition):

Murashov, Mikhail. “Pharmaceutical Impact of the Different Ionization States of a Weakly Basic Drug within a Living Organism.” 2019. Doctoral Dissertation, University of Michigan. Accessed January 22, 2020. http://hdl.handle.net/2027.42/149961.

MLA Handbook (7th Edition):

Murashov, Mikhail. “Pharmaceutical Impact of the Different Ionization States of a Weakly Basic Drug within a Living Organism.” 2019. Web. 22 Jan 2020.

Vancouver:

Murashov M. Pharmaceutical Impact of the Different Ionization States of a Weakly Basic Drug within a Living Organism. [Internet] [Doctoral dissertation]. University of Michigan; 2019. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/2027.42/149961.

Council of Science Editors:

Murashov M. Pharmaceutical Impact of the Different Ionization States of a Weakly Basic Drug within a Living Organism. [Doctoral Dissertation]. University of Michigan; 2019. Available from: http://hdl.handle.net/2027.42/149961

18. Σιαβέλης, Ιωάννης. Μέθοδοι βιοπληροφορικής για τον επαναπροσδιορισμό φαρμάκων στη νόσο Αλτσχάιμερ.

Degree: 2015, University of Patras

Η νόσος Αλτσχάιμερ καταλαμβάνει την πρωτοκαθεδρία στις μη αναστρέψιμες άνοιες με τους επιδημιολογικούς της δείκτες να αυξάνονται όσο μεγαλώνει το προσδόκιμο ζωής του ανθρώπου. Η… (more)

Subjects/Keywords: Νόσος Αλτσχάιμερ; Επαναστόχευση φαρμάκων; Βιοπληροφορική; Μικροσυστοιχίες; Διαφορική έκφραση γονιδίων; 616.831 061; Alzheimer’s disease; Drug repurposing; Bioinformatics; Microarrays; Connectivity map; Differential gene expression

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APA (6th Edition):

Σιαβέλης, . (2015). Μέθοδοι βιοπληροφορικής για τον επαναπροσδιορισμό φαρμάκων στη νόσο Αλτσχάιμερ. (Masters Thesis). University of Patras. Retrieved from http://hdl.handle.net/10889/8782

Chicago Manual of Style (16th Edition):

Σιαβέλης, Ιωάννης. “Μέθοδοι βιοπληροφορικής για τον επαναπροσδιορισμό φαρμάκων στη νόσο Αλτσχάιμερ.” 2015. Masters Thesis, University of Patras. Accessed January 22, 2020. http://hdl.handle.net/10889/8782.

MLA Handbook (7th Edition):

Σιαβέλης, Ιωάννης. “Μέθοδοι βιοπληροφορικής για τον επαναπροσδιορισμό φαρμάκων στη νόσο Αλτσχάιμερ.” 2015. Web. 22 Jan 2020.

Vancouver:

Σιαβέλης . Μέθοδοι βιοπληροφορικής για τον επαναπροσδιορισμό φαρμάκων στη νόσο Αλτσχάιμερ. [Internet] [Masters thesis]. University of Patras; 2015. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/10889/8782.

Council of Science Editors:

Σιαβέλης . Μέθοδοι βιοπληροφορικής για τον επαναπροσδιορισμό φαρμάκων στη νόσο Αλτσχάιμερ. [Masters Thesis]. University of Patras; 2015. Available from: http://hdl.handle.net/10889/8782


University of New Mexico

19. Borunda Duque, Teofilo. Evaluating the Aryl Hydrocarbon Receptor as a Target for Pharmacologic Activity of Repurposed Drugs.

Degree: College of Pharmacy, 2018, University of New Mexico

  The discovery of new pharmacologic targets is important for the advancement of pharmacotherapy and identification of new indications for current drugs. The aryl hydrocarbon… (more)

Subjects/Keywords: Chemicals and Drugs; Medicinal Chemistry and Pharmaceutics; Other Chemicals and Drugs; Pharmacology; Pharmacology, Toxicology and Environmental Health; Toxicology; Aryl Hydrocarbon receptor; Drug Repurposing; Pharmacology; Pharmaceutical target

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APA (6th Edition):

Borunda Duque, T. (2018). Evaluating the Aryl Hydrocarbon Receptor as a Target for Pharmacologic Activity of Repurposed Drugs. (Masters Thesis). University of New Mexico. Retrieved from https://digitalrepository.unm.edu/phrm_etds/19

Chicago Manual of Style (16th Edition):

Borunda Duque, Teofilo. “Evaluating the Aryl Hydrocarbon Receptor as a Target for Pharmacologic Activity of Repurposed Drugs.” 2018. Masters Thesis, University of New Mexico. Accessed January 22, 2020. https://digitalrepository.unm.edu/phrm_etds/19.

MLA Handbook (7th Edition):

Borunda Duque, Teofilo. “Evaluating the Aryl Hydrocarbon Receptor as a Target for Pharmacologic Activity of Repurposed Drugs.” 2018. Web. 22 Jan 2020.

Vancouver:

Borunda Duque T. Evaluating the Aryl Hydrocarbon Receptor as a Target for Pharmacologic Activity of Repurposed Drugs. [Internet] [Masters thesis]. University of New Mexico; 2018. [cited 2020 Jan 22]. Available from: https://digitalrepository.unm.edu/phrm_etds/19.

Council of Science Editors:

Borunda Duque T. Evaluating the Aryl Hydrocarbon Receptor as a Target for Pharmacologic Activity of Repurposed Drugs. [Masters Thesis]. University of New Mexico; 2018. Available from: https://digitalrepository.unm.edu/phrm_etds/19

20. Bourdakou, Marilena. Ανάπτυξη μεθόδων βιοπληροφορικής για την ανάδειξη δικτυακών υπογραφών με σκοπό την κατανόηση μοριακών μηχανισμών και την διερεύνηση υποψήφιων φαρμάκων.

Degree: 2016, National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ)

Systemic approaches are essential in the discovery of disease-specific genes, offering a different perspective and new tools on the analysis of several types of molecular… (more)

Subjects/Keywords: Μέθοδοι επαγωγής δικτυακής συσχέτισης; Δίκτυα συν-έκφρασης; Μοριακοί μηχανισμοί; Επαναπροσδιορισμός φαρμάκων; Μοντέλα τυχαίων περιπάτων; Network inference methods, ,, ,; Co-expression networks; Molecular mechanisms; Drug repurposing; Random walk models

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APA (6th Edition):

Bourdakou, M. (2016). Ανάπτυξη μεθόδων βιοπληροφορικής για την ανάδειξη δικτυακών υπογραφών με σκοπό την κατανόηση μοριακών μηχανισμών και την διερεύνηση υποψήφιων φαρμάκων. (Thesis). National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Retrieved from http://hdl.handle.net/10442/hedi/38230

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Bourdakou, Marilena. “Ανάπτυξη μεθόδων βιοπληροφορικής για την ανάδειξη δικτυακών υπογραφών με σκοπό την κατανόηση μοριακών μηχανισμών και την διερεύνηση υποψήφιων φαρμάκων.” 2016. Thesis, National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Accessed January 22, 2020. http://hdl.handle.net/10442/hedi/38230.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Bourdakou, Marilena. “Ανάπτυξη μεθόδων βιοπληροφορικής για την ανάδειξη δικτυακών υπογραφών με σκοπό την κατανόηση μοριακών μηχανισμών και την διερεύνηση υποψήφιων φαρμάκων.” 2016. Web. 22 Jan 2020.

Vancouver:

Bourdakou M. Ανάπτυξη μεθόδων βιοπληροφορικής για την ανάδειξη δικτυακών υπογραφών με σκοπό την κατανόηση μοριακών μηχανισμών και την διερεύνηση υποψήφιων φαρμάκων. [Internet] [Thesis]. National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ); 2016. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/10442/hedi/38230.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bourdakou M. Ανάπτυξη μεθόδων βιοπληροφορικής για την ανάδειξη δικτυακών υπογραφών με σκοπό την κατανόηση μοριακών μηχανισμών και την διερεύνηση υποψήφιων φαρμάκων. [Thesis]. National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ); 2016. Available from: http://hdl.handle.net/10442/hedi/38230

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

21. Long, Thomas Francis. CAEPIDR: A Computational Approach to Efficient Peptide Influenced Drug Repurposing.

Degree: 2014, Boise State University

 Since the discovery of the molecular basis of disease, numerous studies have reported a correlation between the activity of specific protein receptors the progression of… (more)

Subjects/Keywords: GAMPMS; peptide mutation; drug repurposing; HTVS; multilevel clustering; Pharmaceutical Preparations

…structure data format xiii 1 CHAPTER 1 INTRODUCTION 1.1 1.1.1 Background Drug Repurposing… …an alternative strategy for drug development: drug repurposing. As the name implies, drug… …by the FDA and, if approved, integration into health care. Drug repurposing is either… …repurposing focuses on finding a new use for a specific drug. It is a popular approach for… …of the expenses associated with drug development. Ligand-oriented repurposing is better… 

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APA (6th Edition):

Long, T. F. (2014). CAEPIDR: A Computational Approach to Efficient Peptide Influenced Drug Repurposing. (Thesis). Boise State University. Retrieved from https://scholarworks.boisestate.edu/td/877

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Long, Thomas Francis. “CAEPIDR: A Computational Approach to Efficient Peptide Influenced Drug Repurposing.” 2014. Thesis, Boise State University. Accessed January 22, 2020. https://scholarworks.boisestate.edu/td/877.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Long, Thomas Francis. “CAEPIDR: A Computational Approach to Efficient Peptide Influenced Drug Repurposing.” 2014. Web. 22 Jan 2020.

Vancouver:

Long TF. CAEPIDR: A Computational Approach to Efficient Peptide Influenced Drug Repurposing. [Internet] [Thesis]. Boise State University; 2014. [cited 2020 Jan 22]. Available from: https://scholarworks.boisestate.edu/td/877.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Long TF. CAEPIDR: A Computational Approach to Efficient Peptide Influenced Drug Repurposing. [Thesis]. Boise State University; 2014. Available from: https://scholarworks.boisestate.edu/td/877

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

22. You, Jiaying. Predicting drug - target interaction network using deep learning models for drug repurposing through genetic information.

Degree: Electrical and Computer Engineering, 2018, University of Manitoba

 It has been well-known that biological and experimental methods for drug discovery are time-consuming and expensive. New efforts have been explored to perform drug repurposing(more)

Subjects/Keywords: Drug repurposing; Machine learning; Deep neural network; LASSO

…47 4.3 Drug repurposing using the predicted DTIs… …discovery (a) and drug repurposing (b)… …discovery and drug repurposing Drug development is usually a high cost and time-consuming… …repositioning or drug repurposing. These terminologies are used for finding potential drugs that could… …than 10%, drug repurposing offers a much cheaper and faster way for drug discovery (Fig… 

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APA (6th Edition):

You, J. (2018). Predicting drug - target interaction network using deep learning models for drug repurposing through genetic information. (Masters Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/33458

Chicago Manual of Style (16th Edition):

You, Jiaying. “Predicting drug - target interaction network using deep learning models for drug repurposing through genetic information.” 2018. Masters Thesis, University of Manitoba. Accessed January 22, 2020. http://hdl.handle.net/1993/33458.

MLA Handbook (7th Edition):

You, Jiaying. “Predicting drug - target interaction network using deep learning models for drug repurposing through genetic information.” 2018. Web. 22 Jan 2020.

Vancouver:

You J. Predicting drug - target interaction network using deep learning models for drug repurposing through genetic information. [Internet] [Masters thesis]. University of Manitoba; 2018. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/1993/33458.

Council of Science Editors:

You J. Predicting drug - target interaction network using deep learning models for drug repurposing through genetic information. [Masters Thesis]. University of Manitoba; 2018. Available from: http://hdl.handle.net/1993/33458


Université Paris-Sud – Paris XI

23. Pitayu, Laras. Mitochondrial Disorders Linked to mtDNA instability : From Therapy to Mechanism : Penyakit - penyakit Mitokondria terkait ketidakstabilan mtDNA : dari Terapi Obat menuju Mekanisme Molekuler.

Degree: Docteur es, Sciences de la vie et de la santé, 2015, Université Paris-Sud – Paris XI

L’instabilité d’ADN mitochondrial (ADNmt) peut être quantitative avec la déplétion de l’ADNmt ou qualitative avec des délétions de l’ADNmt. Ces anomalies sont une des causes… (more)

Subjects/Keywords: Instabilité de l’ADNmt; POLG; Clofilium tosylate; Repositionnement thérapeutique; MtDNA instability; POLG; Clofilium tosylate; Drug repurposing; Ketidakstabilan mtDNA; POLG; Clofilium tosylate; Reorientasi penggunaan obat

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APA (6th Edition):

Pitayu, L. (2015). Mitochondrial Disorders Linked to mtDNA instability : From Therapy to Mechanism : Penyakit - penyakit Mitokondria terkait ketidakstabilan mtDNA : dari Terapi Obat menuju Mekanisme Molekuler. (Doctoral Dissertation). Université Paris-Sud – Paris XI. Retrieved from http://www.theses.fr/2015PA112233

Chicago Manual of Style (16th Edition):

Pitayu, Laras. “Mitochondrial Disorders Linked to mtDNA instability : From Therapy to Mechanism : Penyakit - penyakit Mitokondria terkait ketidakstabilan mtDNA : dari Terapi Obat menuju Mekanisme Molekuler.” 2015. Doctoral Dissertation, Université Paris-Sud – Paris XI. Accessed January 22, 2020. http://www.theses.fr/2015PA112233.

MLA Handbook (7th Edition):

Pitayu, Laras. “Mitochondrial Disorders Linked to mtDNA instability : From Therapy to Mechanism : Penyakit - penyakit Mitokondria terkait ketidakstabilan mtDNA : dari Terapi Obat menuju Mekanisme Molekuler.” 2015. Web. 22 Jan 2020.

Vancouver:

Pitayu L. Mitochondrial Disorders Linked to mtDNA instability : From Therapy to Mechanism : Penyakit - penyakit Mitokondria terkait ketidakstabilan mtDNA : dari Terapi Obat menuju Mekanisme Molekuler. [Internet] [Doctoral dissertation]. Université Paris-Sud – Paris XI; 2015. [cited 2020 Jan 22]. Available from: http://www.theses.fr/2015PA112233.

Council of Science Editors:

Pitayu L. Mitochondrial Disorders Linked to mtDNA instability : From Therapy to Mechanism : Penyakit - penyakit Mitokondria terkait ketidakstabilan mtDNA : dari Terapi Obat menuju Mekanisme Molekuler. [Doctoral Dissertation]. Université Paris-Sud – Paris XI; 2015. Available from: http://www.theses.fr/2015PA112233


Northeastern University

24. Devine, William Gilbert. Design, synthesis, and evaluation of inhibitors of trypanosome growth for neglected disease drug discovery.

Degree: PhD, Department of Chemistry and Chemical Biology, 2015, Northeastern University

 Neglected tropical diseases (NTDs) are a global burden affecting the lives of over 1 billion people worldwide. Current chemotherapeutics suffer from a slew of undesirable… (more)

Subjects/Keywords: CYP51; lapatinib; neglected tropical disease; target repurposing; Organic Chemistry; Protein-tyrosine kinase; Inhibitors; Development; Lapatinib; Drug development; Tropical medicine; Trypanosoma; Treatment; African trypanosomiasis; Treatment; Chagas' disease; Treatment; Leishmaniasis; Treatment

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APA (6th Edition):

Devine, W. G. (2015). Design, synthesis, and evaluation of inhibitors of trypanosome growth for neglected disease drug discovery. (Doctoral Dissertation). Northeastern University. Retrieved from http://hdl.handle.net/2047/d20128894

Chicago Manual of Style (16th Edition):

Devine, William Gilbert. “Design, synthesis, and evaluation of inhibitors of trypanosome growth for neglected disease drug discovery.” 2015. Doctoral Dissertation, Northeastern University. Accessed January 22, 2020. http://hdl.handle.net/2047/d20128894.

MLA Handbook (7th Edition):

Devine, William Gilbert. “Design, synthesis, and evaluation of inhibitors of trypanosome growth for neglected disease drug discovery.” 2015. Web. 22 Jan 2020.

Vancouver:

Devine WG. Design, synthesis, and evaluation of inhibitors of trypanosome growth for neglected disease drug discovery. [Internet] [Doctoral dissertation]. Northeastern University; 2015. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/2047/d20128894.

Council of Science Editors:

Devine WG. Design, synthesis, and evaluation of inhibitors of trypanosome growth for neglected disease drug discovery. [Doctoral Dissertation]. Northeastern University; 2015. Available from: http://hdl.handle.net/2047/d20128894


Northeastern University

25. Swaminathan, Uma. Repurposing of human tyrosine kinase inhibitors for neglected diseases:: lead discovery for Chagas disease.

Degree: MS, Department of Chemistry and Chemical Biology, 2015, Northeastern University

 Chapter 1: Neglected tropical disease, Chagas disease and target repurposing approach; The term "Neglected Tropical Diseases" (NTDs) most commonly refers to a group of parasitic… (more)

Subjects/Keywords: Neglected Tropical Diseases; target repurposing approach; Chemistry; Protein-tyrosine kinase; Inhibitors; Protein kinases; Inhibitors; Chagas' disease; Molecular aspects; Lapatinib; Ligands; Tropical medicine; Economic aspects; Developing countries; Drug development; Economic aspects

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APA (6th Edition):

Swaminathan, U. (2015). Repurposing of human tyrosine kinase inhibitors for neglected diseases:: lead discovery for Chagas disease. (Masters Thesis). Northeastern University. Retrieved from http://hdl.handle.net/2047/d20005100

Chicago Manual of Style (16th Edition):

Swaminathan, Uma. “Repurposing of human tyrosine kinase inhibitors for neglected diseases:: lead discovery for Chagas disease.” 2015. Masters Thesis, Northeastern University. Accessed January 22, 2020. http://hdl.handle.net/2047/d20005100.

MLA Handbook (7th Edition):

Swaminathan, Uma. “Repurposing of human tyrosine kinase inhibitors for neglected diseases:: lead discovery for Chagas disease.” 2015. Web. 22 Jan 2020.

Vancouver:

Swaminathan U. Repurposing of human tyrosine kinase inhibitors for neglected diseases:: lead discovery for Chagas disease. [Internet] [Masters thesis]. Northeastern University; 2015. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/2047/d20005100.

Council of Science Editors:

Swaminathan U. Repurposing of human tyrosine kinase inhibitors for neglected diseases:: lead discovery for Chagas disease. [Masters Thesis]. Northeastern University; 2015. Available from: http://hdl.handle.net/2047/d20005100

26. Jary, Calvin. Pre-Clinical Assessment of the Proteasomal Inhibitor Bortezomib as a Generalized Therapeutic Approach for Recessively Inherited Disorders .

Degree: 2017, University of Ottawa

 The number of known monogenic rare diseases (~7000) exceeds the number of effective treatments (~500) by more than an order of magnitude underlining the pressing… (more)

Subjects/Keywords: rare diseases; bortezomib; recessive disorders; velcade; drug repurposing; proteasome inhibitor

…patient. In the meantime repurposing drugs for select rare diseases remains a lower-cost and… …in the cell will inhibit half of all 26S proteasome function. Approximately 83% of the drug… …binds to plasma proteins, this percentage remains constant regardless of drug concentration… …lived proteins by inhibiting the 26S proteasome (Adams et al. 1999). The drug has… …x28;Janssen 2015). The drug is the most practical candidate for interfering with the… 

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Jary, C. (2017). Pre-Clinical Assessment of the Proteasomal Inhibitor Bortezomib as a Generalized Therapeutic Approach for Recessively Inherited Disorders . (Thesis). University of Ottawa. Retrieved from http://hdl.handle.net/10393/36066

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Jary, Calvin. “Pre-Clinical Assessment of the Proteasomal Inhibitor Bortezomib as a Generalized Therapeutic Approach for Recessively Inherited Disorders .” 2017. Thesis, University of Ottawa. Accessed January 22, 2020. http://hdl.handle.net/10393/36066.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Jary, Calvin. “Pre-Clinical Assessment of the Proteasomal Inhibitor Bortezomib as a Generalized Therapeutic Approach for Recessively Inherited Disorders .” 2017. Web. 22 Jan 2020.

Vancouver:

Jary C. Pre-Clinical Assessment of the Proteasomal Inhibitor Bortezomib as a Generalized Therapeutic Approach for Recessively Inherited Disorders . [Internet] [Thesis]. University of Ottawa; 2017. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/10393/36066.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Jary C. Pre-Clinical Assessment of the Proteasomal Inhibitor Bortezomib as a Generalized Therapeutic Approach for Recessively Inherited Disorders . [Thesis]. University of Ottawa; 2017. Available from: http://hdl.handle.net/10393/36066

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


National University of Ireland – Galway

27. Monaghan, David A. Identification of compounds that may be repurposed for the treatment of triple negative breast cancer .

Degree: 2012, National University of Ireland – Galway

 Triple negative breast cancers (TNBC), lack the estrogen and progesterone receptors as well as the HER2 receptor. Currently, there is no selective therapy for the… (more)

Subjects/Keywords: Repurposing; Triple negative breast cancer; Anisomycin; Ciclopirox; Multi-drug resistance; Department of Pharmacology and Therapeutics; National Centre for Biomedical and Engineering Science

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Monaghan, D. A. (2012). Identification of compounds that may be repurposed for the treatment of triple negative breast cancer . (Thesis). National University of Ireland – Galway. Retrieved from http://hdl.handle.net/10379/3829

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Monaghan, David A. “Identification of compounds that may be repurposed for the treatment of triple negative breast cancer .” 2012. Thesis, National University of Ireland – Galway. Accessed January 22, 2020. http://hdl.handle.net/10379/3829.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Monaghan, David A. “Identification of compounds that may be repurposed for the treatment of triple negative breast cancer .” 2012. Web. 22 Jan 2020.

Vancouver:

Monaghan DA. Identification of compounds that may be repurposed for the treatment of triple negative breast cancer . [Internet] [Thesis]. National University of Ireland – Galway; 2012. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/10379/3829.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Monaghan DA. Identification of compounds that may be repurposed for the treatment of triple negative breast cancer . [Thesis]. National University of Ireland – Galway; 2012. Available from: http://hdl.handle.net/10379/3829

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Northeastern University

28. Silva, Lisseth E. Hit-to-lead optimization of kinase-targeted inhibitors of Trypanosoma brucei growth.

Degree: MS, Department of Chemistry and Chemical Biology, 2016, Northeastern University

 Neglected tropical diseases affect over one billion people worldwide. They are "neglected" because they affect the poorest parts of the world and do not attract… (more)

Subjects/Keywords: high throughput screening; human african trypanosomiasis; neglected tropical diseases; sleeping sickness; target repurposing; Protein kinases; Inhibitors; Therapeutic use; Enzyme inhibitors; Therapeutic use; Trypanosoma brucei; African trypanosomiasis; Treatment; Antiparasitic agents; High throughput screening (Drug development); Drug development

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Silva, L. E. (2016). Hit-to-lead optimization of kinase-targeted inhibitors of Trypanosoma brucei growth. (Masters Thesis). Northeastern University. Retrieved from http://hdl.handle.net/2047/D20195406

Chicago Manual of Style (16th Edition):

Silva, Lisseth E. “Hit-to-lead optimization of kinase-targeted inhibitors of Trypanosoma brucei growth.” 2016. Masters Thesis, Northeastern University. Accessed January 22, 2020. http://hdl.handle.net/2047/D20195406.

MLA Handbook (7th Edition):

Silva, Lisseth E. “Hit-to-lead optimization of kinase-targeted inhibitors of Trypanosoma brucei growth.” 2016. Web. 22 Jan 2020.

Vancouver:

Silva LE. Hit-to-lead optimization of kinase-targeted inhibitors of Trypanosoma brucei growth. [Internet] [Masters thesis]. Northeastern University; 2016. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/2047/D20195406.

Council of Science Editors:

Silva LE. Hit-to-lead optimization of kinase-targeted inhibitors of Trypanosoma brucei growth. [Masters Thesis]. Northeastern University; 2016. Available from: http://hdl.handle.net/2047/D20195406

29. Chartier, Matthieu. Développement et applications d’un outil bio-informatique pour la détection de similarités de champs d’interaction moléculaire.

Degree: PhD, Biochimie, 2016, Université de Sherbrooke

 Résumé : Les méthodes de détection de similarités de sites de liaison servent entre autres à la prédiction de fonction et à la prédiction de… (more)

Subjects/Keywords: Champs d'interaction moléculaire; Détection de similarités; Réactivité croisée; Reconnaissance moléculaire; Polypharmacologie; Effets secondaires; Repositionnement de médicaments; Molecular interaction fields; Detection of similarities; Cross-reactivity; Molecular recognition; Polypharmacology; Side-effects; Drug repurposing

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Chartier, M. (2016). Développement et applications d’un outil bio-informatique pour la détection de similarités de champs d’interaction moléculaire. (Doctoral Dissertation). Université de Sherbrooke. Retrieved from http://www.collectionscanada.gc.ca/obj/thesescanada/vol2/QSHERU/TC-QSHERU-11143_8893.pdf ; http://savoirs.usherbrooke.ca/bitstream/11143/8893/1/Chartier_Matthieu_PhD_2016.pdf

Chicago Manual of Style (16th Edition):

Chartier, Matthieu. “Développement et applications d’un outil bio-informatique pour la détection de similarités de champs d’interaction moléculaire.” 2016. Doctoral Dissertation, Université de Sherbrooke. Accessed January 22, 2020. http://www.collectionscanada.gc.ca/obj/thesescanada/vol2/QSHERU/TC-QSHERU-11143_8893.pdf ; http://savoirs.usherbrooke.ca/bitstream/11143/8893/1/Chartier_Matthieu_PhD_2016.pdf.

MLA Handbook (7th Edition):

Chartier, Matthieu. “Développement et applications d’un outil bio-informatique pour la détection de similarités de champs d’interaction moléculaire.” 2016. Web. 22 Jan 2020.

Vancouver:

Chartier M. Développement et applications d’un outil bio-informatique pour la détection de similarités de champs d’interaction moléculaire. [Internet] [Doctoral dissertation]. Université de Sherbrooke; 2016. [cited 2020 Jan 22]. Available from: http://www.collectionscanada.gc.ca/obj/thesescanada/vol2/QSHERU/TC-QSHERU-11143_8893.pdf ; http://savoirs.usherbrooke.ca/bitstream/11143/8893/1/Chartier_Matthieu_PhD_2016.pdf.

Council of Science Editors:

Chartier M. Développement et applications d’un outil bio-informatique pour la détection de similarités de champs d’interaction moléculaire. [Doctoral Dissertation]. Université de Sherbrooke; 2016. Available from: http://www.collectionscanada.gc.ca/obj/thesescanada/vol2/QSHERU/TC-QSHERU-11143_8893.pdf ; http://savoirs.usherbrooke.ca/bitstream/11143/8893/1/Chartier_Matthieu_PhD_2016.pdf


Université de Sherbrooke

30. Chartier, Matthieu. Développement et applications d’un outil bio-informatique pour la détection de similarités de champs d’interaction moléculaire .

Degree: 2016, Université de Sherbrooke

 Résumé : Les méthodes de détection de similarités de sites de liaison servent entre autres à la prédiction de fonction et à la prédiction de… (more)

Subjects/Keywords: Champs d'interaction moléculaire; Détection de similarités; Réactivité croisée; Reconnaissance moléculaire; Polypharmacologie; Effets secondaires; Repositionnement de médicaments; Molecular interaction fields; Detection of similarities; Cross-reactivity; Molecular recognition; Polypharmacology; Side-effects; Drug repurposing

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Chartier, M. (2016). Développement et applications d’un outil bio-informatique pour la détection de similarités de champs d’interaction moléculaire . (Doctoral Dissertation). Université de Sherbrooke. Retrieved from http://hdl.handle.net/11143/8893

Chicago Manual of Style (16th Edition):

Chartier, Matthieu. “Développement et applications d’un outil bio-informatique pour la détection de similarités de champs d’interaction moléculaire .” 2016. Doctoral Dissertation, Université de Sherbrooke. Accessed January 22, 2020. http://hdl.handle.net/11143/8893.

MLA Handbook (7th Edition):

Chartier, Matthieu. “Développement et applications d’un outil bio-informatique pour la détection de similarités de champs d’interaction moléculaire .” 2016. Web. 22 Jan 2020.

Vancouver:

Chartier M. Développement et applications d’un outil bio-informatique pour la détection de similarités de champs d’interaction moléculaire . [Internet] [Doctoral dissertation]. Université de Sherbrooke; 2016. [cited 2020 Jan 22]. Available from: http://hdl.handle.net/11143/8893.

Council of Science Editors:

Chartier M. Développement et applications d’un outil bio-informatique pour la détection de similarités de champs d’interaction moléculaire . [Doctoral Dissertation]. Université de Sherbrooke; 2016. Available from: http://hdl.handle.net/11143/8893

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