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University of Illinois – Urbana-Champaign
1.
Mutyala, Bala.
Epidemiology of prescription drug abuse in Illinois high school students.
Degree: PhD, 0349, 2013, University of Illinois – Urbana-Champaign
URL: http://hdl.handle.net/2142/44778
► Prescription drug abuse has reached epidemic proportions and trends indicate that the number of adolescents who abuse these drugs will continue to increase. Every adolescent…
(more)
▼ Prescription drug abuse has reached epidemic proportions and trends indicate that the number of adolescents who abuse these drugs will continue to increase. Every adolescent appear to be at risk and this epidemic does not appear to be defined by known risk profiles for substance abuse. Nearly one in every five 12th grade students used
prescription drugs for non-medical reasons at least once in lifetime according to the Monitoring the Future study. This is a significant public health problem as
prescription drug abuse in the adolescence can continue into the adult life and puts adolescents at risk of substance abuse and other comorbidities. The purpose of this study was to identify individual, family, school and community level factors responsible for the initiation and maintenance of
prescription drug abuse behaviors in Illinois 12th grade students.
A cross-sectional study design was used with the secondary data on the 12th graders’
prescription drug use from the 2010 Illinois Youth Survey. Multilevel logistic regression was performed to account for the multistage sampling and hierarchical structure of the data, using software such as HLM, STATA, and SPSS. Abuse of any
prescription drug and of subclasses such as uppers, downers, steroids and other drugs were the dependent variables. Individual level variables such as age, gender, race, socioeconomic status, having clear college/future plans, other substance/over the counter (OTC)
drug abuse, depression, gambling, family rules about alcohol and
drug use, perceived peer
drug use; school level variables such as the percent of -White students, students in the low socioeconomic status category, students reporting bullying, students reporting unsafe at school; and school district level variables such as community norms towards substance abuse, community activities, safety, location and availability of alcohol, tobacco and other drugs (ATOD) were examined for their influence on
prescription drug abuse in Illinois 12th graders.
Results indicate that Illinois 12th graders (11.4%) had a lower prevalence than the US prevalence (15.4%) in the year 2009. After adjusting for all the other variables in the multilevel logistic regression model, Illinois 12th graders with past year ATOD use (Odds ratio (OR): 6.095, 95% CI: 2.708,13.717), past year OTC
drug use (OR: 6.081, 95% CI: 3.952,9.358), past year depression (OR: 2.381, 95% CI: 1.475, 3.844), and past year gambling (OR: 1.684, 95% CI: 1.069, 2.655) were found to have significantly higher odds of
prescription drug abuse in 12th graders. Other individual level variables and all school/ school district level variables were found to be not significantly associated with
prescription drug abuse in 12th graders.
Prescription drug abuse in Illinois 12th graders was significantly different from prevalence in US 12th graders and was found to be significantly associated with gender, past year ATOD use, OTC use, gambling, depression, and perceived peer
drug use. Most of the variation in
prescription drug abuse appears to be within the…
Advisors/Committee Members: Alston, Reginald J. (advisor), Alston, Reginald J. (Committee Chair), Farner, Susan M. (committee member), Graber, Kim C. (committee member), Mulhall, Peter F. (committee member).
Subjects/Keywords: Prescription Drug Abuse
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mutyala, B. (2013). Epidemiology of prescription drug abuse in Illinois high school students. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/44778
Chicago Manual of Style (16th Edition):
Mutyala, Bala. “Epidemiology of prescription drug abuse in Illinois high school students.” 2013. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed February 28, 2021.
http://hdl.handle.net/2142/44778.
MLA Handbook (7th Edition):
Mutyala, Bala. “Epidemiology of prescription drug abuse in Illinois high school students.” 2013. Web. 28 Feb 2021.
Vancouver:
Mutyala B. Epidemiology of prescription drug abuse in Illinois high school students. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2013. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/2142/44778.
Council of Science Editors:
Mutyala B. Epidemiology of prescription drug abuse in Illinois high school students. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2013. Available from: http://hdl.handle.net/2142/44778

University of North Texas
2.
Carey, Caitlyn.
Anxiety Sensitivity and Non-Medical Prescription Drug Use among Adolescents.
Degree: 2020, University of North Texas
URL: https://digital.library.unt.edu/ark:/67531/metadc1707265/
► Research suggests that non-medical prescription drug (NMPD) use is becoming increasingly prevalent, particularly among adolescents. A critical step towards developing effective intervention efforts requires identifying…
(more)
▼ Research suggests that non-medical
prescription drug (NMPD) use is becoming increasingly prevalent, particularly among adolescents. A critical step towards developing effective intervention efforts requires identifying adolescents who are at risk for NMPD use. An extensive literature suggests that both adolescents and adults with elevated anxiety sensitivity (AS) are at greater risk for problematic substance use, and a small body of work has identified similar links with NMPD use specifically among adults. However, most of this literature combines all
prescription drugs into a single category, and no work has evaluated the relation between AS and NMPD use among adolescents. The current study endeavors to further this area of research by examining the relation between AS (overall and subscales) and NMPD use among adolescents. The project evaluated 276 adolescents (age 9-19 years) enrolled in a residential treatment program on level of AS, including sub-dimensions (i.e., cognitive, physical, and social), and NMPD use across three categories of drugs: analgesic (e.g., Vicodin®), anxiolytic (e.g., Xanax®), and stimulant (e.g., Adderall®). A series of logistic regression models indicated that overall AS predicted nonmedical analgesic use, but not anxiolytic/sedative or stimulant use. A closer investigation of the AS subscales demonstrated that only the AS social subscale significantly predicted nonmedical analgesic and anxiolytic/sedative use. These results suggest that AS is related to NMPD use among adolescents, highlighting the need for future work to disaggregate the assessment of NMPD use into specific
drug classes and explore the subscale dimensions of AS.
Advisors/Committee Members: Blumenthal, Heidemarie, Guillot, Casey, Kelly, Kimberly.
Subjects/Keywords: adolescents; anxiety sensitivity; AS; nonmedical prescription drug use; NMPD; NMPD use; NMPDU; prescription drug use; prescription drug misuse
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Penn State University
3.
Nam, Young Hee.
Prescription Drug Policies and Health Care: Studies on Medicare Part D Program, State Prescription Drug Monitoring Programs, and Off-label Prescribing Practices.
Degree: 2014, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/22830
► This dissertation investigated three prescription drug policy areas, aiming to fill in the gap in the research toward reforming health care in a positive direction:…
(more)
▼ This dissertation investigated three
prescription drug policy areas, aiming to fill in the gap in the research toward reforming health care in a positive direction: (1) Medicare Part D program, (2) state
prescription drug monitoring programs (PDMPs), and (3) off-label prescribing practices.
The Medicare Part D program study examined Part D’s effects on health outcomes and Medicare spending for Parts A and B among Part D beneficiaries who previously lacked
prescription drug coverage, using Medicare Current Beneficiary Survey (MCBS) Cost and Use files for 2004-2007, which are combined with Medicare claims and other administrative data, and a difference-in-differences model, estimating Part D’s treatment effects between 2005 and 2007. The results showed that Part D benefits did not have statistically significant effects on health outcomes and Medicare Parts A and B spending among the study population. In subpopulation analysis, people who previously had hypertension showed slightly, but significantly, decreased general health status and increased Medicare spending for home health agency services.
The second study on PDMPs examined PDMPs’ effects in reducing
drug overdose mortality rates in the United States during 1999-2010. The main data used are (1) de-identified individual-level mortality data obtained from the National Center for Health Statistics (NCHS) and (2) bridged-race population estimates data produced by the U.S. Census Bureau in collaboration with NCHS. The PDMP effects on
drug overdose mortality rates were estimated using three different fixed effects models. The results suggested that PDMPs had little effect in reducing
drug overdose mortality rates and might be related to unintended consequences, such as increased
drug overdose deaths from illegal or unspecified drugs.
The third study on off-label prescribing of drugs aimed to investigate individuals’ understanding, experience, and preferences on off-label prescribing of drugs from the perspective of patient-centered care, employing concurrent, embedded mixed methods. The primary quantitative and qualitative data were collected through a survey, on-line and off-line, among community-dwelling senior citizens age 60 and older residing in a county in Pennsylvania. The study found that an absolute majority of individuals (96 percent of the respondents) wanted to be informed of off-label
prescription, and the reasons included: to make informed decision; to determine the existence and the level of scientific evidence supporting the off-label
drug use; to have a partnership with physicians in their treatment; and because of their belief that making informed decisions is a patient’s right.
Advisors/Committee Members: Dennis G Shea, Dissertation Advisor/Co-Advisor, Dennis G Shea, Committee Chair/Co-Chair, Pamela Farley Short, Committee Member, John Raymond Moran Jr., Committee Member, Douglas L Leslie, Committee Member.
Subjects/Keywords: Prescription drug policies; Medicare Part D; PDMPs; Off-label prescription
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Nam, Y. H. (2014). Prescription Drug Policies and Health Care: Studies on Medicare Part D Program, State Prescription Drug Monitoring Programs, and Off-label Prescribing Practices. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/22830
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Nam, Young Hee. “Prescription Drug Policies and Health Care: Studies on Medicare Part D Program, State Prescription Drug Monitoring Programs, and Off-label Prescribing Practices.” 2014. Thesis, Penn State University. Accessed February 28, 2021.
https://submit-etda.libraries.psu.edu/catalog/22830.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Nam, Young Hee. “Prescription Drug Policies and Health Care: Studies on Medicare Part D Program, State Prescription Drug Monitoring Programs, and Off-label Prescribing Practices.” 2014. Web. 28 Feb 2021.
Vancouver:
Nam YH. Prescription Drug Policies and Health Care: Studies on Medicare Part D Program, State Prescription Drug Monitoring Programs, and Off-label Prescribing Practices. [Internet] [Thesis]. Penn State University; 2014. [cited 2021 Feb 28].
Available from: https://submit-etda.libraries.psu.edu/catalog/22830.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Nam YH. Prescription Drug Policies and Health Care: Studies on Medicare Part D Program, State Prescription Drug Monitoring Programs, and Off-label Prescribing Practices. [Thesis]. Penn State University; 2014. Available from: https://submit-etda.libraries.psu.edu/catalog/22830
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
4.
Darmon, David.
Les déterminants de la prescription médicamenteuse en médecine générale : The determinants of drug prescription in general practice.
Degree: Docteur es, Épidemiologie. Santé publique. Recherche sur les services de santé, 2014, Université Claude Bernard – Lyon I
URL: http://www.theses.fr/2014LYO10318
► La prescription de médicaments s'accompagne de bénéfices en santé mais aussi de conséquences iatrogéniques, économiques, environnementales et écologiques. Elle tient une place centrale dans la…
(more)
▼ La
prescription de médicaments s'accompagne de bénéfices en santé mais aussi de conséquences iatrogéniques, économiques, environnementales et écologiques. Elle tient une place centrale dans la relation entre le patient et le médecin. En médecine générale en France, 78 % à 90 % des consultations aboutiraient à une
prescription médicamenteuse versus 72 % en Allemagne et 43 % aux Pays-Bas. Le médicament est un produit complexe soumis à des logiques industrielles et de santé publique contradictoires. Sa
prescription est l'aboutissement d'une décision médicale qui tient compte, dans le cadre de l'evidence-based-medicine, des données de la science, de l'expérience du médecin et des choix du patient. D'autres déterminants peuvent influencer la
prescription médicamenteuse : certaines caractéristiques des maladies, des patients, des médecins et du système de soin. Afin d'identifier ces déterminants, nous avons mené une revue systématique de la littérature pour rechercher les facteurs associés au nombre de médicaments prescrits en médecine générale. Puis, à partir de l'étude épidémiologique nationale ECOGEN, nous avons identifié les facteurs liés à la
prescription médicamenteuse en médecine générale en France. Pour étudier plus précisément la
prescription de médicaments chez les patients atteints de maladies chroniques, nous avons mené une étude épidémiologique évaluant les facteurs associés à la
prescription d'antibiotiques et d'anxiolytiques/hypnotiques aux patients asthmatiques en médecine générale en France et en Italie. Enfin, nous avons étudié la place des fonctionnalités liées à la
prescription médicamenteuse dans les logiciels médicaux en France. La revue de la littérature a montré que les déterminants du nombre de médicaments prescrits en médecine générale étaient souvent liés à l'existence d'une maladie chronique, aux caractéristiques sociodémographiques des patients (personnes âgées, femmes, faible statut socioéconomique et faible niveau d'éducation) et aux caractéristiques de travail du médecin tel que le nombre de consultations par jour. L'étude épidémiologique réalisée en médecine générale en France a montré qu'un médicament était plus fréquemment prescrit aux femmes (OR : 1,12 [1,04-1,20]) et aux individus âgés de plus de 60 ans (OR : 1,35 [1,20-1,53]) ou de moins de 15 ans (OR : 1,51 [1,29-1,78]. Les médecins recevant les visiteurs de l'industrie pharmaceutique étaient aussi plus susceptibles de prescrire un médicament (OR : 1,19 [1,01-1,41]). L'étude comparant l'Italie à la France a montré que les généralistes français prescrivaient plus d'anxiolytiques/hypnotiques (17.8% vs. 6.9%, p<0.0001) mais moins d'antibiotiques (37.1% vs. 42.2%, p<0.00001) que les généralistes italiens aux patients asthmatiques. Cette étude a aussi montré qu'en France comme en Italie, les femmes asthmatiques avaient plus souvent une
prescription d'antibiotiques (OR : 1.5 [1.3-1.7]) et d'anxiolytiques/hypnotiques (OR : 1.8[1.5-2.1]) que les hommes asthmatiques. Enfin, l'étude des logiciels de consultation des médecins généralistes…
Advisors/Committee Members: Letrilliart, Laurent (thesis director).
Subjects/Keywords: Prescription; Médecine générale; Médicaments; Prescription; General practice; Drug; 610
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Darmon, D. (2014). Les déterminants de la prescription médicamenteuse en médecine générale : The determinants of drug prescription in general practice. (Doctoral Dissertation). Université Claude Bernard – Lyon I. Retrieved from http://www.theses.fr/2014LYO10318
Chicago Manual of Style (16th Edition):
Darmon, David. “Les déterminants de la prescription médicamenteuse en médecine générale : The determinants of drug prescription in general practice.” 2014. Doctoral Dissertation, Université Claude Bernard – Lyon I. Accessed February 28, 2021.
http://www.theses.fr/2014LYO10318.
MLA Handbook (7th Edition):
Darmon, David. “Les déterminants de la prescription médicamenteuse en médecine générale : The determinants of drug prescription in general practice.” 2014. Web. 28 Feb 2021.
Vancouver:
Darmon D. Les déterminants de la prescription médicamenteuse en médecine générale : The determinants of drug prescription in general practice. [Internet] [Doctoral dissertation]. Université Claude Bernard – Lyon I; 2014. [cited 2021 Feb 28].
Available from: http://www.theses.fr/2014LYO10318.
Council of Science Editors:
Darmon D. Les déterminants de la prescription médicamenteuse en médecine générale : The determinants of drug prescription in general practice. [Doctoral Dissertation]. Université Claude Bernard – Lyon I; 2014. Available from: http://www.theses.fr/2014LYO10318

Nelson Mandela Metropolitan University
5.
Dranitsaris, George.
Development of a value based pricing index for new drugs in metastatic colorectal cancer.
Degree: Faculty of Health Sciences, 2012, Nelson Mandela Metropolitan University
URL: http://hdl.handle.net/10948/d1009310
► Background: Worldwide, prices for cancer drugs have been under downward pressure where several governments have mandated price cuts of branded and generic products. A better…
(more)
▼ Background: Worldwide, prices for cancer drugs have been under downward pressure where several governments have mandated price cuts of branded and generic products. A better alternative to mandated price cuts would be the estimation of a launch price based on drug performance, cost effectiveness and a country’s ability to pay. In this study, the development of a global pricing index for new drugs that encompasses all of these attributes in patients with metastatic colorectal cancer (mCRC) is described. Methods: A pharmacoeconomic model was developed to simulate clinical outcomes in mCRC patients receiving chemotherapy with the addition of a “new drug” that improves survival by 1.4, 3 and 6 months. Cost and health state utility data were obtained from cancer centers and oncology nurses (total n=112) in Canada (n=24), Spain (n=24), India (n=24), South Africa (n=16) and Malaysia (n=24). A price per dose was estimated for each survival increment using a target value threshold of three times the per capita gross domestic product (GDP) for each country, as recommended by the World Health Organisation (WHO). Multivariable analysis was then used to develop the pricing index, which considers survival benefit, per capita GDP and income dispersion as measured by the Gini coefficient as predictor variables. Results: Higher survival benefits were associated with elevated drug prices, especially in wealthier countries such as Canada and Spain. For a nation like Argentina with a per capita GDP of 15,000 and a Gini coefficient of 51, it is estimated that for a drug which provides a 4 month survival benefit in mCRC, the value based price would be US 630 per dose. In contrast, the same drug in a wealthier country like Norway could command a price of US 2,775 and still be considered cost effective according to the WHO criteria. Conclusions: A global pricing index was presented that can be used to estimate a value based price in different countries for new drugs in mCRC. The application of this index to estimate a price based on cost effectiveness would be a good starting point for opening dialogue between the key stakeholders and a better alternative to governments’ mandated price cuts.
Subjects/Keywords: Drug – Prices; Prescription pricing; Pharmaceutical industry – Prices
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Dranitsaris, G. (2012). Development of a value based pricing index for new drugs in metastatic colorectal cancer. (Thesis). Nelson Mandela Metropolitan University. Retrieved from http://hdl.handle.net/10948/d1009310
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Dranitsaris, George. “Development of a value based pricing index for new drugs in metastatic colorectal cancer.” 2012. Thesis, Nelson Mandela Metropolitan University. Accessed February 28, 2021.
http://hdl.handle.net/10948/d1009310.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Dranitsaris, George. “Development of a value based pricing index for new drugs in metastatic colorectal cancer.” 2012. Web. 28 Feb 2021.
Vancouver:
Dranitsaris G. Development of a value based pricing index for new drugs in metastatic colorectal cancer. [Internet] [Thesis]. Nelson Mandela Metropolitan University; 2012. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/10948/d1009310.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Dranitsaris G. Development of a value based pricing index for new drugs in metastatic colorectal cancer. [Thesis]. Nelson Mandela Metropolitan University; 2012. Available from: http://hdl.handle.net/10948/d1009310
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade do Rio Grande do Norte
6.
Dantas, Tayne Anderson Cortez.
A propaganda de medicamentos voltados à clínica obstétrica e/ou ginecológica e sua influência sobre a prescrição
.
Degree: 2012, Universidade do Rio Grande do Norte
URL: http://repositorio.ufrn.br/handle/123456789/13473
► INTRODUCTION: Drug advertisement stimulates self-medication and irrational use of medicines, especially when it starts to interfere in the prescription. Monitoring advertisements, as well as the…
(more)
▼ INTRODUCTION:
Drug advertisement stimulates self-medication and irrational use of
medicines, especially when it starts to interfere in the
prescription. Monitoring
advertisements, as well as the observation of its influence on health professionals,
prescriptions become necessary because of this public health problem. OBJECTIVE:
The aim of this work was to analyze
drug advertisements directed to gynecologists
and/or obstetricians doctors relating them to the current legislation as well as its
influence on
prescription. METHODOLOGY: The sample was composed of
drug
advertisements divulged to the gynecologists and / or obstetricians doctors and was
analyzed according to RDC96/2008. To evaluate the influence of advertisement on
prescription, a questionnaire was administered to gynecologists / obstetricians
doctors and prescriptions of a public maternity were also evaluated. RESULTS AND
CONCLUSION: Concerning the advertisements analyzed, 48% complied fully with
current legislation and 52% of the advertisements analyzed were in accordance to
the RDC No. 96/2008 in most of the items evaluated. The doctors interviewed are
used to receive the visits of propagandists, even in the public service, receiving gifts
offered by the industry and believe that medicine advertisement tries to influence
prescribing. Many of them use the material provided by the propagandist as a source
for their
prescription, although they present a critical view about them information.
The use of trade name / mark on the
prescription is a common practice among the
doctors interviewed, even in the public service, suggesting there is an influence of
medicine advertisement on the
prescription
Advisors/Committee Members: Dantas, Maria Cleide Ribeiro (advisor), CPF:13908464404 (advisor), http://lattes.cnpq.br/8260624403804292 (advisor).
Subjects/Keywords: Medicamentos. Propaganda. Prescrição.;
Drug. Advertisement. Prescription.
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Dantas, T. A. C. (2012). A propaganda de medicamentos voltados à clínica obstétrica e/ou ginecológica e sua influência sobre a prescrição
. (Thesis). Universidade do Rio Grande do Norte. Retrieved from http://repositorio.ufrn.br/handle/123456789/13473
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Dantas, Tayne Anderson Cortez. “A propaganda de medicamentos voltados à clínica obstétrica e/ou ginecológica e sua influência sobre a prescrição
.” 2012. Thesis, Universidade do Rio Grande do Norte. Accessed February 28, 2021.
http://repositorio.ufrn.br/handle/123456789/13473.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Dantas, Tayne Anderson Cortez. “A propaganda de medicamentos voltados à clínica obstétrica e/ou ginecológica e sua influência sobre a prescrição
.” 2012. Web. 28 Feb 2021.
Vancouver:
Dantas TAC. A propaganda de medicamentos voltados à clínica obstétrica e/ou ginecológica e sua influência sobre a prescrição
. [Internet] [Thesis]. Universidade do Rio Grande do Norte; 2012. [cited 2021 Feb 28].
Available from: http://repositorio.ufrn.br/handle/123456789/13473.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Dantas TAC. A propaganda de medicamentos voltados à clínica obstétrica e/ou ginecológica e sua influência sobre a prescrição
. [Thesis]. Universidade do Rio Grande do Norte; 2012. Available from: http://repositorio.ufrn.br/handle/123456789/13473
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade do Rio Grande do Norte
7.
Dantas, Tayne Anderson Cortez.
A propaganda de medicamentos voltados à clínica obstétrica e/ou ginecológica e sua influência sobre a prescrição
.
Degree: 2012, Universidade do Rio Grande do Norte
URL: http://repositorio.ufrn.br/handle/123456789/13473
► INTRODUCTION: Drug advertisement stimulates self-medication and irrational use of medicines, especially when it starts to interfere in the prescription. Monitoring advertisements, as well as the…
(more)
▼ INTRODUCTION:
Drug advertisement stimulates self-medication and irrational use of
medicines, especially when it starts to interfere in the
prescription. Monitoring
advertisements, as well as the observation of its influence on health professionals,
prescriptions become necessary because of this public health problem. OBJECTIVE:
The aim of this work was to analyze
drug advertisements directed to gynecologists
and/or obstetricians doctors relating them to the current legislation as well as its
influence on
prescription. METHODOLOGY: The sample was composed of
drug
advertisements divulged to the gynecologists and / or obstetricians doctors and was
analyzed according to RDC96/2008. To evaluate the influence of advertisement on
prescription, a questionnaire was administered to gynecologists / obstetricians
doctors and prescriptions of a public maternity were also evaluated. RESULTS AND
CONCLUSION: Concerning the advertisements analyzed, 48% complied fully with
current legislation and 52% of the advertisements analyzed were in accordance to
the RDC No. 96/2008 in most of the items evaluated. The doctors interviewed are
used to receive the visits of propagandists, even in the public service, receiving gifts
offered by the industry and believe that medicine advertisement tries to influence
prescribing. Many of them use the material provided by the propagandist as a source
for their
prescription, although they present a critical view about them information.
The use of trade name / mark on the
prescription is a common practice among the
doctors interviewed, even in the public service, suggesting there is an influence of
medicine advertisement on the
prescription
Advisors/Committee Members: Dantas, Maria Cleide Ribeiro (advisor), CPF:13908464404 (advisor), http://lattes.cnpq.br/8260624403804292 (advisor).
Subjects/Keywords: Medicamentos. Propaganda. Prescrição.;
Drug. Advertisement. Prescription.
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Dantas, T. A. C. (2012). A propaganda de medicamentos voltados à clínica obstétrica e/ou ginecológica e sua influência sobre a prescrição
. (Masters Thesis). Universidade do Rio Grande do Norte. Retrieved from http://repositorio.ufrn.br/handle/123456789/13473
Chicago Manual of Style (16th Edition):
Dantas, Tayne Anderson Cortez. “A propaganda de medicamentos voltados à clínica obstétrica e/ou ginecológica e sua influência sobre a prescrição
.” 2012. Masters Thesis, Universidade do Rio Grande do Norte. Accessed February 28, 2021.
http://repositorio.ufrn.br/handle/123456789/13473.
MLA Handbook (7th Edition):
Dantas, Tayne Anderson Cortez. “A propaganda de medicamentos voltados à clínica obstétrica e/ou ginecológica e sua influência sobre a prescrição
.” 2012. Web. 28 Feb 2021.
Vancouver:
Dantas TAC. A propaganda de medicamentos voltados à clínica obstétrica e/ou ginecológica e sua influência sobre a prescrição
. [Internet] [Masters thesis]. Universidade do Rio Grande do Norte; 2012. [cited 2021 Feb 28].
Available from: http://repositorio.ufrn.br/handle/123456789/13473.
Council of Science Editors:
Dantas TAC. A propaganda de medicamentos voltados à clínica obstétrica e/ou ginecológica e sua influência sobre a prescrição
. [Masters Thesis]. Universidade do Rio Grande do Norte; 2012. Available from: http://repositorio.ufrn.br/handle/123456789/13473

Queens University
8.
Pulver, Ariel.
Recreational use of prescription medications among Canadian young people: Identifying demographic and geographic disparities
.
Degree: Community Health and Epidemiology, 2013, Queens University
URL: http://hdl.handle.net/1974/8369
► BACKGROUND: The nonmedical use of prescription medications among young people has escalated substantially in recent years. Certain subgroups of adolescents are at greater risk than…
(more)
▼ BACKGROUND: The nonmedical use of prescription medications among young people has escalated substantially in recent years. Certain subgroups of adolescents are at greater risk than others, including rural youth, however this has yet to be adequately quantified in Canada, and risk and protective factors in rural communities remain understudied.
OBJECTIVES: The first objective of this thesis was to characterize the nonmedical use of prescription drugs in Canadian youth by age, gender, socioeconomic, immigrant and geographic statuses. The second objective was to examine time-use patterns among rural young people as they may relate to their risk of using prescription drugs recreationally.
METHODS: Data were obtained from 10,429 youth in grades 9 and 10 across Canada who participated in the 2009/2010 Cycle of the Health Behaviour in School-aged Children survey. Participants documented information about their nonmedical use of opioid pain relievers, stimulants and sedative or tranquilizer medications in the past year. Cross-tabulations and multi-level regression analyses were used to determine proportions and estimate risk by demographic subgroups, and among 2393 rural youth, to examine associations with time-use patterns
RESULTS: Females were 1.25 times more likely to report recreational use of pain relievers (95% CI: 1.04-1.51). Lower SES students were 2.41 times more likely to report recreational use of any type of medication (95% CI: 1.94-2.99). Pain reliever use was highest among rural youth living in close proximity to urban centres. Frequent peer time after school and in the evenings was associated with a 1.73 (95% CI: 1.10-2.73) and 2.16 times (95% CI: 1.30-3.60) increased risk of using prescription drugs recreationally, however associations were attenuated when adjusted for other risk factors. Non-participation in extracurricular activities was associated with a 50% increase in risk for nonmedical use of prescription drugs, even when adjusted for other risk factors.
CONCLUSIONS: Females, those of low SES and some rural youth, especially those who do not participate in extracurricular activities, are at increased risk for using prescription drugs recreationally. Results from this thesis point to priority areas for public health and education in reducing harms associated with nonmedical use of prescription drugs.
Subjects/Keywords: Epidemiology
;
Prescription drug abuse
;
Adolescent
;
Substance abuse
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Pulver, A. (2013). Recreational use of prescription medications among Canadian young people: Identifying demographic and geographic disparities
. (Thesis). Queens University. Retrieved from http://hdl.handle.net/1974/8369
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Pulver, Ariel. “Recreational use of prescription medications among Canadian young people: Identifying demographic and geographic disparities
.” 2013. Thesis, Queens University. Accessed February 28, 2021.
http://hdl.handle.net/1974/8369.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Pulver, Ariel. “Recreational use of prescription medications among Canadian young people: Identifying demographic and geographic disparities
.” 2013. Web. 28 Feb 2021.
Vancouver:
Pulver A. Recreational use of prescription medications among Canadian young people: Identifying demographic and geographic disparities
. [Internet] [Thesis]. Queens University; 2013. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/1974/8369.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Pulver A. Recreational use of prescription medications among Canadian young people: Identifying demographic and geographic disparities
. [Thesis]. Queens University; 2013. Available from: http://hdl.handle.net/1974/8369
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Sydney
9.
Blanch, Bianca.
What is normal? A critical analysis of the methods quantifying prescription drug use and potential misuse in pharmaceutical claims
.
Degree: 2016, University of Sydney
URL: http://hdl.handle.net/2123/16910
► Our overall objective is to examine methods of quantifying prescription drug misuse in pharmaceutical claims. We approach this by undertaking a systematic review of the…
(more)
▼ Our overall objective is to examine methods of quantifying prescription drug misuse in pharmaceutical claims. We approach this by undertaking a systematic review of the global literature measuring the extent of prescription drug misuse in pharmaceutical claims. Our review highlights four measures, number of prescribers, number of dispensing pharmacies, volume of drug dispensed and number of early refills, are used frequently to define prescription drug misuse. Despite this homogeneity, we found heterogeneity in the thresholds delineating use from misuse and a lack of established or validated benchmarks to accurately measure misuse in pharmaceutical claims. In our empirical work, we focus on prescription opioid analgesics due to the recent and considerable global increase in use and opioid- related harms. We use publically available, routinely collected data to document increases in prescription opioid use and related harms in Australia over 20 years. Over three chapters we explore population norms of prescription drug access in national dispensing claims and examine how access patterns relate to the metrics defining ‘misuse’ identified in our systematic review. We compare prescription drug access in Australia and British Columbia, Canada, for prescription opioids and statins, drug classes with high or no known abuse potential, respectively. We found access norms are remarkably similar across drug classes and healthcare settings. However, extreme access patterns are more common in people dispensed opioids, younger age groups or those receiving income assistance. We then examine opioid access in Australian adults initiating or reinitiating strong opioid treatment. We found the standard metrics defining ‘misuse’, including doctor and pharmacy shopping, are non-specific in that they identify misuse, but are also likely to capture high-need patient groups including individuals with a history of cancer treatment. From a translational perspective, our findings are particularly important as the US Food and Drug Administration recently endorsed using routinely collected data, including pharmaceutical claims, to quantify prescription opioid misuse and measure the effectiveness of interventions aimed to curb the ‘opioid epidemic’. We recommend using these commonly established metrics with caution due to their inability to isolate a population of people misusing opioids.
Subjects/Keywords: Prescription drug;
opioidanalgesic;
epidemiology;
pharmaceutical benefits scheme
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Blanch, B. (2016). What is normal? A critical analysis of the methods quantifying prescription drug use and potential misuse in pharmaceutical claims
. (Thesis). University of Sydney. Retrieved from http://hdl.handle.net/2123/16910
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Blanch, Bianca. “What is normal? A critical analysis of the methods quantifying prescription drug use and potential misuse in pharmaceutical claims
.” 2016. Thesis, University of Sydney. Accessed February 28, 2021.
http://hdl.handle.net/2123/16910.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Blanch, Bianca. “What is normal? A critical analysis of the methods quantifying prescription drug use and potential misuse in pharmaceutical claims
.” 2016. Web. 28 Feb 2021.
Vancouver:
Blanch B. What is normal? A critical analysis of the methods quantifying prescription drug use and potential misuse in pharmaceutical claims
. [Internet] [Thesis]. University of Sydney; 2016. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/2123/16910.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Blanch B. What is normal? A critical analysis of the methods quantifying prescription drug use and potential misuse in pharmaceutical claims
. [Thesis]. University of Sydney; 2016. Available from: http://hdl.handle.net/2123/16910
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Xavier University
10.
Gallagher, Lisa A.
College Students' Perceptions of Prescription and
Non-Prescription Drug Use.
Degree: Doctor of Psychology (Psy.D.), Psychology, 2018, Xavier University
URL: http://rave.ohiolink.edu/etdc/view?acc_num=xavier152811430792606
► Nonmedical use of prescription stimulants is increasingly common among college students (Schulenberg, Johnston, O’Malley, Bachman, Miech, & Patrick, 2017). Research into the motives behind this…
(more)
▼ Nonmedical use of
prescription stimulants is
increasingly common among college students (Schulenberg, Johnston,
O’Malley, Bachman, Miech, & Patrick, 2017). Research into the
motives behind this behavior indicates that students most often use
prescription stimulants to enhance academic performance in response
to academic stress, although there is little empirical data to
suggest that using stimulants leads to positive academic outcomes.
Factors that appear to perpetuate
prescription stimulant use on
college campuses include low perceived risk and high social
acceptability associated with using diverted stimulants to improve
academic functioning. The current study used experimental and
self-report methods to compare perceptions stimulant use for
academic purposes to other types of
drug use for utilitarian and
recreational purposes in a sample (N = 243 ; 79% Caucasian; 65.4%
women) of college students. In general, approval of all forms of
drug use, with the exception of recreational marijuana and alcohol
use, was low. Consistent with hypotheses, results indicated that
college students rated a peer who used Adderall for academic
purposes significantly more favorably than a peer who used
Adderall, Vicodin, or marijuana for recreation. However, overall
social acceptability ratings for all types of diverted
prescription
drug use were low. This suggests that although students view using
prescription stimulants as a study aid more favorably than other
types of
drug use, they still do believe that this is a socially
unacceptable behavior.
Advisors/Committee Members: Kenford, Susan (Advisor).
Subjects/Keywords: Psychology; Prescription drug use, stimulants, Adderall, NMPDM,
non-prescription drug use, diverted prescription use, college
students, non medical prescription drug misuse, perceptions of drug
use, substance misuse
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Gallagher, L. A. (2018). College Students' Perceptions of Prescription and
Non-Prescription Drug Use. (Doctoral Dissertation). Xavier University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=xavier152811430792606
Chicago Manual of Style (16th Edition):
Gallagher, Lisa A. “College Students' Perceptions of Prescription and
Non-Prescription Drug Use.” 2018. Doctoral Dissertation, Xavier University. Accessed February 28, 2021.
http://rave.ohiolink.edu/etdc/view?acc_num=xavier152811430792606.
MLA Handbook (7th Edition):
Gallagher, Lisa A. “College Students' Perceptions of Prescription and
Non-Prescription Drug Use.” 2018. Web. 28 Feb 2021.
Vancouver:
Gallagher LA. College Students' Perceptions of Prescription and
Non-Prescription Drug Use. [Internet] [Doctoral dissertation]. Xavier University; 2018. [cited 2021 Feb 28].
Available from: http://rave.ohiolink.edu/etdc/view?acc_num=xavier152811430792606.
Council of Science Editors:
Gallagher LA. College Students' Perceptions of Prescription and
Non-Prescription Drug Use. [Doctoral Dissertation]. Xavier University; 2018. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=xavier152811430792606

Drexel University
11.
Ekejiuba, Kelechi.
A Strategic Approach to Decreasing Prescription Drug Abuse amongst College Students.
Degree: 2012, Drexel University
URL: http://hdl.handle.net/1860/4020
► Objectives: To assess the attitudes and culture of prescription drug misuse amongst undergraduate students. To assess students knowledge of, their perceived risks, and severity of…
(more)
▼ Objectives: To assess the attitudes and culture of prescription drug misuse amongst undergraduate students. To assess students knowledge of, their perceived risks, and severity of misusing prescription drugs, and the accessibility of prescription drugs on campus. To examine the relationship between academic status and prescription drug misuse. To develop a Public Service Announcement to create awareness on this issue, and propose appropriate prevention programs using the Ecological Model of behavioral change. Methods: This is a cross-sectional study involving 50 undergraduate Drexel University students, ages 18 and older. Students were recruited from the Main Campus to complete an anonymous 35-question survey to assess their perceptions, beliefs, and attitudes towards prescription drug misuse. Results: 22% of students in this study reported misusing prescription drugs in their lifetime, while 44% of students reported abusing illicit drugs in their lifetime. Older students 24 years old and above are more likely to misuse prescription drugs than younger students. Most students reported stimulants (58%) and painkillers (52%) to be the most accessible prescription drugs on campus. 90% of students reported marijuana as the most accessible illegal drug. 70% of students feel that they could gain access to prescription drugs by asking other students on campus, with 40% of students claiming to know at least one student to ask for prescription drugs. In this study, academic status was not significantly correlated with prescription drug misuse; however, students with lower grade point average appeared to misuse prescription drugs more than students with higher grade point average. Perceived risks and severity of prescription drug misuse varied; however, majority of students reported some risks associated with prescription drug and illegal drug abuse. Conclusions: Lifetime misuse of prescription and illicit drugs is somewhat common amongst Drexel University undergraduate students surveyed at the Main Campus. This study found that students risk perceptions about drug misuse and their perceived ease of access to drugs could influence their choice to abuse prescription and illicit drugs. It was difficult proving statistical significance for some correlations due to the sample size of this study. Hence, a larger sample study on this topic is recommended in order to be able to generalize the findings to the rest of the Drexel University students. A PSA is being done to create awareness on this issue, and correct students misunderstanding of the effects of drug misuse and prevention programs should be put in place through the C.H.O.I.C.E.S Center at Drexel University.
M.P.H., Public Health – Drexel University, 2012
Advisors/Committee Members: Lankenau, Stephen.
Subjects/Keywords: Public Health; College Students; Prescription Drug Abuse
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ekejiuba, K. (2012). A Strategic Approach to Decreasing Prescription Drug Abuse amongst College Students. (Thesis). Drexel University. Retrieved from http://hdl.handle.net/1860/4020
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Ekejiuba, Kelechi. “A Strategic Approach to Decreasing Prescription Drug Abuse amongst College Students.” 2012. Thesis, Drexel University. Accessed February 28, 2021.
http://hdl.handle.net/1860/4020.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Ekejiuba, Kelechi. “A Strategic Approach to Decreasing Prescription Drug Abuse amongst College Students.” 2012. Web. 28 Feb 2021.
Vancouver:
Ekejiuba K. A Strategic Approach to Decreasing Prescription Drug Abuse amongst College Students. [Internet] [Thesis]. Drexel University; 2012. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/1860/4020.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Ekejiuba K. A Strategic Approach to Decreasing Prescription Drug Abuse amongst College Students. [Thesis]. Drexel University; 2012. Available from: http://hdl.handle.net/1860/4020
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of New South Wales
12.
Hulme, Shann.
The diversion and supply of pharmaceutical drugs for non-medical use.
Degree: Public Health & Community Medicine, 2019, University of New South Wales
URL: http://handle.unsw.edu.au/1959.4/64889
;
https://unsworks.unsw.edu.au/fapi/datastream/unsworks:62847/SOURCE02?view=true
► Consistent with international trends, in 2016 Australia experienced its highest number of drug-related deaths in 20 years, with most attributed to pharmaceutical opioids and benzodiazepines.…
(more)
▼ Consistent with international trends, in 2016 Australia experienced its highest number of
drug-related deaths in 20 years, with most attributed to pharmaceutical opioids and benzodiazepines. A large international evidence-base exists on mechanisms, drivers and profitability of illicit
drug supply, yet equivalent research examining pharmaceutical drugs is scarce. This thesis aimed to fill this gap by examining, through four empirical studies, the diversion and supply of pharmaceutical drugs for non-medical use.First, a systematic review and meta-analysis pooled results from 34 international studies to estimate the prevalence of medical and non-medical/intermediary sourcing and diversion. Most pharmaceuticals for non-medical use were sourced via friends/family (57%, 95% CI 53%-62%) and few studies examined supply beyond end-user perspectives. Addressing this gap, the role of health practitioners and suppliers in Australia was explored next. Diversion from the medical system was examined through 117 cases of health practitioner misconduct using AustLII records. Persistent over-prescribing by a small number of practitioners due to inadequate skills to manage complex patient groups was identified. The final two empirical chapters analysed data from semi-structured interviews with 51 people involved in supplying pharmaceutical drugs. Negative binomial regressions and thematic analysis explored
drug sourcing and motivations. Suppliers used medical (47% legitimate, 7% illegitimate prescriptions) and intermediary sources (e.g. 18% friends/family) and were financially (65%) and/or altruistically (61%) motivated. Those using illegitimate medical sources distributed larger quantities, while altruistically motivated suppliers distributed smaller quantities (e.g. leftover supplies) to people with perceived therapeutic need. Mark-up calculations showed that for every dollar-invested, suppliers earned 3.19 (median) or 19.90 (mean). Mixed-effects regressions found mark-up was predicted by source, such that mark-up was higher for medically sourced drugs, compared with those sourced via intermediaries (median 13.49 cf. 1.23).This research holds implications for research, policy and practice. The supply chain for pharmaceutical diversion is shorter than for illicit drugs and supply mechanisms and motives are diverse, warranting multifaceted responses. For example: 1)
prescription monitoring for the small number of high-volume suppliers, 2) broader education for social supply, 3) consideration of supplier motive at sentencing, 4) support for health practitioners, and 5) addressing demand factors in marginalised populations.
Advisors/Committee Members: Nielsen, Suzanne, Monash University, Hughes, Caitlin, Flinders University.
Subjects/Keywords: Drug supply; Pharmaceutical diversion; Prescription drug misuse; Black market; Drug dealing
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Hulme, S. (2019). The diversion and supply of pharmaceutical drugs for non-medical use. (Doctoral Dissertation). University of New South Wales. Retrieved from http://handle.unsw.edu.au/1959.4/64889 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:62847/SOURCE02?view=true
Chicago Manual of Style (16th Edition):
Hulme, Shann. “The diversion and supply of pharmaceutical drugs for non-medical use.” 2019. Doctoral Dissertation, University of New South Wales. Accessed February 28, 2021.
http://handle.unsw.edu.au/1959.4/64889 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:62847/SOURCE02?view=true.
MLA Handbook (7th Edition):
Hulme, Shann. “The diversion and supply of pharmaceutical drugs for non-medical use.” 2019. Web. 28 Feb 2021.
Vancouver:
Hulme S. The diversion and supply of pharmaceutical drugs for non-medical use. [Internet] [Doctoral dissertation]. University of New South Wales; 2019. [cited 2021 Feb 28].
Available from: http://handle.unsw.edu.au/1959.4/64889 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:62847/SOURCE02?view=true.
Council of Science Editors:
Hulme S. The diversion and supply of pharmaceutical drugs for non-medical use. [Doctoral Dissertation]. University of New South Wales; 2019. Available from: http://handle.unsw.edu.au/1959.4/64889 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:62847/SOURCE02?view=true

University of Louisville
13.
Friley, Lorin Brooke.
Teenage pharmapocalypse? : an exploratory examination of prescription drug abuse.
Degree: MA, 2011, University of Louisville
URL: 10.18297/etd/461
;
https://ir.library.louisville.edu/etd/461
► The purpose of this study was to examine the phenomenon of teenage prescription drug abuse in Jefferson County, Kentucky to gain a better understanding of…
(more)
▼ The purpose of this study was to examine the phenomenon of teenage
prescription drug abuse in Jefferson County, Kentucky to gain a better understanding of the environment and characteristics of a teenager who abuses
prescription drugs, and to gain insight into this situation through the perspectives of adult professionals who regularly work with teenagers. In-depth interviews were conducted with five professionals, and data analyses were performed to determine recurring themes. There were four primary emergent themes, including: profiling of a teenage
prescription drug abuser; factors influencing likelihood of
drug abuse; portfolio of mental, emotional, and social issues; and treatment processes. There was general consensus among interviewees that there is no "typical" profile of a teen who abuses
prescription drugs. There are many convening factors that contribute to the likelihood a teen will abuse
prescription drugs, including peer influence and familial influence. Teens who abuse
prescription drugs generally present with a multitude of mental health issues, coping difficulties, and social struggles. If a teen who is abusing
prescription drugs receives treatment, there are generally many cycles of unsuccessful treatment programs prior to a success.
Advisors/Committee Members: Walker, Kandi L..
Subjects/Keywords: Teenage prescription drug abuse; Adolescent prescription drug abuse; Adolescent drug abuse; Adolescent substance abuse; Teenage substance use; Adolescent substance use
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Friley, L. B. (2011). Teenage pharmapocalypse? : an exploratory examination of prescription drug abuse. (Masters Thesis). University of Louisville. Retrieved from 10.18297/etd/461 ; https://ir.library.louisville.edu/etd/461
Chicago Manual of Style (16th Edition):
Friley, Lorin Brooke. “Teenage pharmapocalypse? : an exploratory examination of prescription drug abuse.” 2011. Masters Thesis, University of Louisville. Accessed February 28, 2021.
10.18297/etd/461 ; https://ir.library.louisville.edu/etd/461.
MLA Handbook (7th Edition):
Friley, Lorin Brooke. “Teenage pharmapocalypse? : an exploratory examination of prescription drug abuse.” 2011. Web. 28 Feb 2021.
Vancouver:
Friley LB. Teenage pharmapocalypse? : an exploratory examination of prescription drug abuse. [Internet] [Masters thesis]. University of Louisville; 2011. [cited 2021 Feb 28].
Available from: 10.18297/etd/461 ; https://ir.library.louisville.edu/etd/461.
Council of Science Editors:
Friley LB. Teenage pharmapocalypse? : an exploratory examination of prescription drug abuse. [Masters Thesis]. University of Louisville; 2011. Available from: 10.18297/etd/461 ; https://ir.library.louisville.edu/etd/461

University of Toronto
14.
Zhang, Yang Maria.
Novel Approaches in Assessing Abuse Potential of Psychotropic Medications – Pregabalin as a Test Case.
Degree: 2016, University of Toronto
URL: http://hdl.handle.net/1807/71706
► Abuse of psychotropic medications causes significant morbidity and mortality in North America. Results from traditional assessments of abuse liability may not be generalizable to individuals…
(more)
▼ Abuse of psychotropic medications causes significant morbidity and mortality in North America. Results from traditional assessments of abuse liability may not be generalizable to individuals with mental illnesses or for drugs with ill-defined mechanisms of action. Pregabalin is an anticonvulsant medication used off-label to manage benzodiazepine withdrawal symptoms. Simultaneously, reports of its abuse have emerged. Two novel approaches were used to assess pregabalin’s abuse potential. On the macro-level, adverse drug reaction data from Canada’s national database were evaluated in Study 1. Results indicated that cases found in this spontaneous reporting system can provide early indicators of prescription drug abuse. On the micro-level, Study 2 aimed to assess the acute effects of pregabalin in inpatients withdrawing from benzodiazepines and produced valuable information concerning study design, which can be used to inform future research. Overall, these novel macro-and micro-level approaches in assessing abuse potential of psychotropic drugs are complementary and synergistic with traditional methods.
M.Sc.
Advisors/Committee Members: Sproule, Beth A, Pharmaceutical Sciences.
Subjects/Keywords: addiction; database; drug abuse; pregabalin; prescription drug abuse; psychotropic; 0572
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Zhang, Y. M. (2016). Novel Approaches in Assessing Abuse Potential of Psychotropic Medications – Pregabalin as a Test Case. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/71706
Chicago Manual of Style (16th Edition):
Zhang, Yang Maria. “Novel Approaches in Assessing Abuse Potential of Psychotropic Medications – Pregabalin as a Test Case.” 2016. Masters Thesis, University of Toronto. Accessed February 28, 2021.
http://hdl.handle.net/1807/71706.
MLA Handbook (7th Edition):
Zhang, Yang Maria. “Novel Approaches in Assessing Abuse Potential of Psychotropic Medications – Pregabalin as a Test Case.” 2016. Web. 28 Feb 2021.
Vancouver:
Zhang YM. Novel Approaches in Assessing Abuse Potential of Psychotropic Medications – Pregabalin as a Test Case. [Internet] [Masters thesis]. University of Toronto; 2016. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/1807/71706.
Council of Science Editors:
Zhang YM. Novel Approaches in Assessing Abuse Potential of Psychotropic Medications – Pregabalin as a Test Case. [Masters Thesis]. University of Toronto; 2016. Available from: http://hdl.handle.net/1807/71706

Georgia State University
15.
Zesiger, Heather A, PhD.
Opioid Misuse Among Students Pursuing Higher Education.
Degree: PhD, Public Health, 2018, Georgia State University
URL: https://scholarworks.gsu.edu/sph_diss/22
► Background: Despite national attention on opioid abuse, little is known about opioid misuse (OM; defined as heroin use or non-medical use of opioid prescription…
(more)
▼ Background: Despite national attention on opioid abuse, little is known about opioid misuse (OM; defined as heroin use or non-medical use of opioid
prescription drugs) among students pursuing higher education in the United States. A better understanding of student OM is necessary to inform a public health process to develop campus-specific prevention strategies and interventions. This dissertation examined three main questions: 1) what individual, social and institutional characteristics are associated with OM, 2) Is OM elevated among student service members/veterans, and 3) whether OM is associated with comorbidities including mental and physical diagnoses, sleep, and suicidality, as well as whether the effect of OM on suicidality is mediated by its effects on sleep quality?
Methods: Data were from full-time students (N = 91,322) enrolled at 103 institutions that participated in the spring 2015 American College Health Association–National College Health Assessment survey. Multilevel modeling and binary logistic regression were used to examine associations between individual, social, and school-level predictors and OM.
Results: The prevalence of opioid misuse was 7% (N = 6,376). OM was associated with several individual, social and institutional characteristics, such as being an undergraduate versus graduate student (OR = 1.26, 95% CI = [1.179, 1.348]). Analyses showed that being a student service member/veteran (SSM/V) who had served in hazardous duty increased the odds of OM by roughly 31% (OR = 1.309, 95% CI = 1.113, 1.539). Likewise, students who reported misusing opioids were twice as likely to report having suicidal ideation or a past suicide attempt (OR = 2.317, 95% CI = [2.193, 2.448]), and a number of other health outcomes, such as chronic illness, anxiety, and depression. Mediation analyses in MPlus showed that sleeping difficulties partially mediated the relationship between OM and suicidality.
Conclusion: OM has devastating economic, social and medical consequences for individuals and communities. Significant associations between individual characteristics, comorbid conditions, and social environmental structures and OM among students in higher education highlight the need to illuminate other risk and protective factors as well as to identify effective clinical and environmental interventions to reduce harm and save lives on campus.
Advisors/Committee Members: Sheryl Strasser, PhD, Ashli Owen-Smith, PhD, Michael Huey, MD.
Subjects/Keywords: drug use; students; prescription drug misuse; heroin; suicide; veterans
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Chicago ·
MLA ·
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APA (6th Edition):
Zesiger, Heather A, P. (2018). Opioid Misuse Among Students Pursuing Higher Education. (Doctoral Dissertation). Georgia State University. Retrieved from https://scholarworks.gsu.edu/sph_diss/22
Chicago Manual of Style (16th Edition):
Zesiger, Heather A, PhD. “Opioid Misuse Among Students Pursuing Higher Education.” 2018. Doctoral Dissertation, Georgia State University. Accessed February 28, 2021.
https://scholarworks.gsu.edu/sph_diss/22.
MLA Handbook (7th Edition):
Zesiger, Heather A, PhD. “Opioid Misuse Among Students Pursuing Higher Education.” 2018. Web. 28 Feb 2021.
Vancouver:
Zesiger, Heather A P. Opioid Misuse Among Students Pursuing Higher Education. [Internet] [Doctoral dissertation]. Georgia State University; 2018. [cited 2021 Feb 28].
Available from: https://scholarworks.gsu.edu/sph_diss/22.
Council of Science Editors:
Zesiger, Heather A P. Opioid Misuse Among Students Pursuing Higher Education. [Doctoral Dissertation]. Georgia State University; 2018. Available from: https://scholarworks.gsu.edu/sph_diss/22

Vanderbilt University
16.
White, Steven John.
Design and implementation of a computerized informatics tool to facilitate clinician access to a state’s prescription drug monitoring program database.
Degree: MS, Biomedical Informatics, 2013, Vanderbilt University
URL: http://hdl.handle.net/1803/10791
► BIOMEDICAL INFORMATICS DESIGN AND IMPLEMENTATION OF A COMPUTERIZED INFORMATICS TOOL TO FACILITATE CLINICIAN ACCESS TO A STATE’S PRESCRIPTION DRUG MONITORING PROGRAM DATABASE STEVEN JOHN WHITE…
(more)
▼ BIOMEDICAL INFORMATICS
DESIGN AND IMPLEMENTATION OF A COMPUTERIZED INFORMATICS TOOL TO FACILITATE CLINICIAN ACCESS TO A STATE’S
PRESCRIPTION DRUG MONITORING PROGRAM DATABASE
STEVEN JOHN WHITE
Thesis under the direction of Professor Dario Giuse
Within the past decade,
prescription drug abuse has emerged as a nationwide epidemic, with opioid-related poisoning deaths more than tripling since 1999. In an effort to bring this public health crisis under control, 43 states, including Tennessee, have enacted
prescription drug monitoring programs (PDMPs), computerized databases of DEA-controlled substance prescriptions filled at pharmacies within the given state. Such programs have been found to be effective in curbing
prescription opioid abuse by alerting prescribers to aberrant
prescription-filling activity. However, they are commonly underutilized and have workflow barriers that impede clinical use.
Ideally, PDMP queries could be generated seamlessly from within a medical enterprise’s electronic health record (EHR) system, using an application-programming interface (API) supplied by the state’s PDMP vendor. However, the enabling legislative language currently prohibits such access. Therefore, we developed and evaluated a Perl software program activated from within Vanderbilt University Medical Center’s EHR patient chart to send the properly coded/formatted user and patient-demographic information packets to the Tennessee PDMP website, without the use of an API. The program parses the returned data file for important
prescription information and displays the filtered information to the user. By allowing the query to occur in the background, the user’s tether time to the computer is decreased from 3 minutes to 10 seconds per query.
During the evaluation phase, we used a quasi-experimental intervention design with two alternating 2-week control and intervention periods. Twenty-eight ED attending physicians participated in the study and queried the PDMP at their clinical discretion. During integrated PDMP query tool availability, 5.9 % (169/2844) of emergency department patients were screened compared with 2.2 % (62/2786) during periods when the tool was not available (p<0.001, Pearson’s Chi square). Data was not viewed in 20% of integrated tool assisted queries. The EHR-integrated PDMP query tool was well regarded by study physicians as an enhancement to workflow.
Advisors/Committee Members: Dominik Aronsky (committee member), Ian Jones (committee member), Dario Giuse (Committee Chair).
Subjects/Keywords: controlled substances monitoring database; opioid prescriptions; opioid abuse; prescription misuse; prescription abuse; drug-seeking; prescription monitoring program; PMP; CSMD
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
White, S. J. (2013). Design and implementation of a computerized informatics tool to facilitate clinician access to a state’s prescription drug monitoring program database. (Thesis). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/10791
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
White, Steven John. “Design and implementation of a computerized informatics tool to facilitate clinician access to a state’s prescription drug monitoring program database.” 2013. Thesis, Vanderbilt University. Accessed February 28, 2021.
http://hdl.handle.net/1803/10791.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
White, Steven John. “Design and implementation of a computerized informatics tool to facilitate clinician access to a state’s prescription drug monitoring program database.” 2013. Web. 28 Feb 2021.
Vancouver:
White SJ. Design and implementation of a computerized informatics tool to facilitate clinician access to a state’s prescription drug monitoring program database. [Internet] [Thesis]. Vanderbilt University; 2013. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/1803/10791.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
White SJ. Design and implementation of a computerized informatics tool to facilitate clinician access to a state’s prescription drug monitoring program database. [Thesis]. Vanderbilt University; 2013. Available from: http://hdl.handle.net/1803/10791
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Florida
17.
Delcher, Philip Chris.
MONITORING OPIOID ABUSE AND DOCTOR SHOPPING AN EPIDEMIOLOGIC PERSPECTIVE IN PERSON, PLACE, AND TIME.
Degree: PhD, Epidemiology, 2014, University of Florida
URL: https://ufdc.ufl.edu/UFE0046666
► Prescription drug abuse is a national epidemic in the United States. Prescription pain relievers, in particular, are highly abused despite regulatory oversight to control their…
(more)
▼ Prescription drug abuse is a national epidemic in the United States.
Prescription pain relievers, in particular, are highly abused despite regulatory oversight to control their distribution. Electronic databases, known as
prescription drug monitoring programs (PDMPs), are designed to monitor the prescribing and dispensing of controlled substances, including
prescription pain relievers, and identify patients who inappropriately seek drugs from mulitple providers (doctor shopping).
Advisors/Committee Members: MALDONADO MOLINA,MILDRED MERISA (committee chair), COOK,ROBERT L (committee member), GOLDBERGER,BRUCE A (committee member).
Subjects/Keywords: Death; Drug prescriptions; Health care industry; Medicaid; Mortality; Opioid analgesics; Pain; Predisposing factors; Prescription drugs; Shopping; abuse – drug – prescription
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Delcher, P. C. (2014). MONITORING OPIOID ABUSE AND DOCTOR SHOPPING AN EPIDEMIOLOGIC PERSPECTIVE IN PERSON, PLACE, AND TIME. (Doctoral Dissertation). University of Florida. Retrieved from https://ufdc.ufl.edu/UFE0046666
Chicago Manual of Style (16th Edition):
Delcher, Philip Chris. “MONITORING OPIOID ABUSE AND DOCTOR SHOPPING AN EPIDEMIOLOGIC PERSPECTIVE IN PERSON, PLACE, AND TIME.” 2014. Doctoral Dissertation, University of Florida. Accessed February 28, 2021.
https://ufdc.ufl.edu/UFE0046666.
MLA Handbook (7th Edition):
Delcher, Philip Chris. “MONITORING OPIOID ABUSE AND DOCTOR SHOPPING AN EPIDEMIOLOGIC PERSPECTIVE IN PERSON, PLACE, AND TIME.” 2014. Web. 28 Feb 2021.
Vancouver:
Delcher PC. MONITORING OPIOID ABUSE AND DOCTOR SHOPPING AN EPIDEMIOLOGIC PERSPECTIVE IN PERSON, PLACE, AND TIME. [Internet] [Doctoral dissertation]. University of Florida; 2014. [cited 2021 Feb 28].
Available from: https://ufdc.ufl.edu/UFE0046666.
Council of Science Editors:
Delcher PC. MONITORING OPIOID ABUSE AND DOCTOR SHOPPING AN EPIDEMIOLOGIC PERSPECTIVE IN PERSON, PLACE, AND TIME. [Doctoral Dissertation]. University of Florida; 2014. Available from: https://ufdc.ufl.edu/UFE0046666

Mississippi State University
18.
Kinman, Brittany A.
Using the Health Belief Model to identify factors that prevent non-prescription stimulant use.
Degree: PhD, Psychology, 2018, Mississippi State University
URL: http://sun.library.msstate.edu/ETD-db/theses/available/etd-06282018-114641/
;
► The present study used the Health Belief Model (HBM) to better understand how perceived susceptibility and severity (perceived threat) can contribute to college students…
(more)
▼ The present study used the Health Belief Model (HBM) to better understand how perceived susceptibility and severity (perceived threat) can contribute to college students willingness to use non-
prescription stimulants (NPS). Prior research has shown that as the perceived threat of use increased college students intentions to use NPS has decreased (Sattler, Mehlkop, & Graeff, 2013). The psychology research pool was used to recruit 1067 non-user undergraduate students to complete the vignettes and the survey. Participants were given one of sixteen different vignettes that manipulated the perceived threat for academic and health consequences associated with NPS use. Data analyses showed that a combination of high perceived academic threat (high susceptibility and severity) along with high health susceptibility yielded the lowest willingness to use NPS. Therefore, the higher susceptibility that an academic and health consequence will occur along with the higher severity of an academic consequence will occur predicted the lowest intentions to use NPS. Future research should continue to examine what factors can best deter non-users and users from using NPS.
Advisors/Committee Members: Dr. Kevin J. Armstrong (chair), Dr. Kristina B. Hood (chair), Dr. Cliff McKinney (committee member), Dr. Michael Nadorff (committee member).
Subjects/Keywords: drug use; stimulant use; non-prescription stimulant use; college students
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kinman, B. A. (2018). Using the Health Belief Model to identify factors that prevent non-prescription stimulant use. (Doctoral Dissertation). Mississippi State University. Retrieved from http://sun.library.msstate.edu/ETD-db/theses/available/etd-06282018-114641/ ;
Chicago Manual of Style (16th Edition):
Kinman, Brittany A. “Using the Health Belief Model to identify factors that prevent non-prescription stimulant use.” 2018. Doctoral Dissertation, Mississippi State University. Accessed February 28, 2021.
http://sun.library.msstate.edu/ETD-db/theses/available/etd-06282018-114641/ ;.
MLA Handbook (7th Edition):
Kinman, Brittany A. “Using the Health Belief Model to identify factors that prevent non-prescription stimulant use.” 2018. Web. 28 Feb 2021.
Vancouver:
Kinman BA. Using the Health Belief Model to identify factors that prevent non-prescription stimulant use. [Internet] [Doctoral dissertation]. Mississippi State University; 2018. [cited 2021 Feb 28].
Available from: http://sun.library.msstate.edu/ETD-db/theses/available/etd-06282018-114641/ ;.
Council of Science Editors:
Kinman BA. Using the Health Belief Model to identify factors that prevent non-prescription stimulant use. [Doctoral Dissertation]. Mississippi State University; 2018. Available from: http://sun.library.msstate.edu/ETD-db/theses/available/etd-06282018-114641/ ;

University of Utah
19.
Kitchens, Connie L.
Identification of behavioral risk factors for medically unsupervised use of prescription medications in Utah.
Degree: PhD, Family & Preventive Medicine;, 2010, University of Utah
URL: http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/1359/rec/603
► Prescription drug misuse has become a widespread problem in the United States. Misuse of prescription drugs is second only to marijuana as the nation’s most…
(more)
▼ Prescription drug misuse has become a widespread problem in the United States. Misuse of prescription drugs is second only to marijuana as the nation’s most prevalent drug problem. National data shows that in 2002–2003 through 2005–2006, Utah ranked among those states with the highest rates of the past year nonmedical use of pain relievers among those age 12 and older. Using data from the 2008 Utah Behavioral Risk Factor Surveillance System (N=5,330) and the 2007 Utah Higher Education Health Behavior Survey (N=8,834), we completed three studies exploring nonmedical prescription drug use among the Utah adult opulation. There were three different outcomes: medically unsupervised use of prescription pain medication; obtaining prescription drugs for nonmedical purposes; and using prescription drugs to manage pain. The last two outcomes were within the population of Utah college students.
Subjects/Keywords: Nonmedical prescription drug use; Risk factors; Medication abuse
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APA ·
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MLA ·
Vancouver ·
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Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kitchens, C. L. (2010). Identification of behavioral risk factors for medically unsupervised use of prescription medications in Utah. (Doctoral Dissertation). University of Utah. Retrieved from http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/1359/rec/603
Chicago Manual of Style (16th Edition):
Kitchens, Connie L. “Identification of behavioral risk factors for medically unsupervised use of prescription medications in Utah.” 2010. Doctoral Dissertation, University of Utah. Accessed February 28, 2021.
http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/1359/rec/603.
MLA Handbook (7th Edition):
Kitchens, Connie L. “Identification of behavioral risk factors for medically unsupervised use of prescription medications in Utah.” 2010. Web. 28 Feb 2021.
Vancouver:
Kitchens CL. Identification of behavioral risk factors for medically unsupervised use of prescription medications in Utah. [Internet] [Doctoral dissertation]. University of Utah; 2010. [cited 2021 Feb 28].
Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/1359/rec/603.
Council of Science Editors:
Kitchens CL. Identification of behavioral risk factors for medically unsupervised use of prescription medications in Utah. [Doctoral Dissertation]. University of Utah; 2010. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/1359/rec/603

Temple University
20.
Neelakantan, Harshini.
REWARD-RELATED BEHAVIORAL EFFECTS OF PRESCRIPTION OPIOIDS AS A FUNCTION OF PUTATIVE ACUTE AND CHRONIC PAIN-LIKE STATES IN MALE AND FEMALE C57BL/6 MICE.
Degree: PhD, 2014, Temple University
URL: http://digital.library.temple.edu/u?/p245801coll10,270439
► Pharmaceutical Sciences
Pain is a leading cause of disability and the most common reason for clinical care. The field of pain research has focused on…
(more)
▼ Pharmaceutical Sciences
Pain is a leading cause of disability and the most common reason for clinical care. The field of pain research has focused on sex differences in the recent years with an expansive body of literature demonstrating sex-related differences in pain behavior and responsiveness to pharmacological interventions. Prescription opioids are potent analgesics and the mainstay for the clinical management of moderate-to-severe acute and chronic pain conditions. However, the long-term clinical use of prescription opioids for chronic pain remains controversial due to concerns about severe adverse effects, including tolerance, dependence, and addiction associated with opioid use. The non-medical use and abuse of prescription opioids has become a public health crisis, the problem even arising in a subset of chronic pain patients receiving opioid therapy. The vulnerability factors, specifically the role of pain in the propensity to prescription opioid abuse, are poorly understood. The present research project sought to investigate the propensity to opioid reward as a function of pain in male and female mice by incorporating acute (acetic acid-induced) visceral nociceptive and chronic chemotherapy (paclitaxel)-induced peripheral neuropathic pain models. Sexually dimorphic variations in the sensitivities of mice to nociceptive and allodynic behaviors were initially assessed using the two putative pain models. Following that, the two prescription opioids, morphine and oxycodone were examined under both pain contexts and the capacity of the two prescription opioids to produce reward-related behavioral effects were measured using drug discrimination, conditioned place preference, and intravenous drug self-administration procedures. The presence of acute noxious state but not chronic pain selectively attenuated the discriminative stimulus effects of the prescription opioid, morphine in male mice. The magnitude of modulation of the stimulus effects of opioids by the acute noxious state were further observed to be inversely related to the relative intrinsic antinociceptive effectiveness of the two opioids in reversing the acute noxious state and sex-specific sensitivities of mice to opioid-induced antinociception. In contrast, while no change was observed in opioid-reward as a function of the acute noxious state in both sexes, the presence of paclitaxel-induced chronic pain opioid-selectively and dose-selectively enhanced the conditioned rewarding effect of morphine (0.3 mg/kg dose), and the effect was more pronounced in male relative to female mice. These data were further supported by the self-administration results, in that the reinforcing efficacy (breakpoints under progressive ratio (PR) responding) and the incentive-motivational salience of morphine significantly increased in the presence of chronic pain in male mice, while non-selectively increasing regardless of the presence/absence of pain in female mice. Overall, the converging empirical evidence presented here suggest that these models provide preclinical…
Advisors/Committee Members: Walker, Ellen A.;, Raffa, Robert B., Rawls, Scott M., Canney, Daniel J., Comer, Sandra D.;.
Subjects/Keywords: Pharmacology;
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Neelakantan, H. (2014). REWARD-RELATED BEHAVIORAL EFFECTS OF PRESCRIPTION OPIOIDS AS A FUNCTION OF PUTATIVE ACUTE AND CHRONIC PAIN-LIKE STATES IN MALE AND FEMALE C57BL/6 MICE. (Doctoral Dissertation). Temple University. Retrieved from http://digital.library.temple.edu/u?/p245801coll10,270439
Chicago Manual of Style (16th Edition):
Neelakantan, Harshini. “REWARD-RELATED BEHAVIORAL EFFECTS OF PRESCRIPTION OPIOIDS AS A FUNCTION OF PUTATIVE ACUTE AND CHRONIC PAIN-LIKE STATES IN MALE AND FEMALE C57BL/6 MICE.” 2014. Doctoral Dissertation, Temple University. Accessed February 28, 2021.
http://digital.library.temple.edu/u?/p245801coll10,270439.
MLA Handbook (7th Edition):
Neelakantan, Harshini. “REWARD-RELATED BEHAVIORAL EFFECTS OF PRESCRIPTION OPIOIDS AS A FUNCTION OF PUTATIVE ACUTE AND CHRONIC PAIN-LIKE STATES IN MALE AND FEMALE C57BL/6 MICE.” 2014. Web. 28 Feb 2021.
Vancouver:
Neelakantan H. REWARD-RELATED BEHAVIORAL EFFECTS OF PRESCRIPTION OPIOIDS AS A FUNCTION OF PUTATIVE ACUTE AND CHRONIC PAIN-LIKE STATES IN MALE AND FEMALE C57BL/6 MICE. [Internet] [Doctoral dissertation]. Temple University; 2014. [cited 2021 Feb 28].
Available from: http://digital.library.temple.edu/u?/p245801coll10,270439.
Council of Science Editors:
Neelakantan H. REWARD-RELATED BEHAVIORAL EFFECTS OF PRESCRIPTION OPIOIDS AS A FUNCTION OF PUTATIVE ACUTE AND CHRONIC PAIN-LIKE STATES IN MALE AND FEMALE C57BL/6 MICE. [Doctoral Dissertation]. Temple University; 2014. Available from: http://digital.library.temple.edu/u?/p245801coll10,270439

Vanderbilt University
21.
Philip Gentry, Anne Elissa.
Safety and Effectiveness: The FDA’s Approach to Risk in Prescription Medication.
Degree: PhD, Law and Economics, 2016, Vanderbilt University
URL: http://hdl.handle.net/1803/12003
► The Food and Drug Administration (FDA) regulates the risks associated with pharmaceutical products; however, some drug uses are not directly regulated, and appropriate usage is…
(more)
▼ The Food and
Drug Administration (FDA) regulates the risks associated with pharmaceutical products; however, some
drug uses are not directly regulated, and appropriate usage is left to the physician’s discretion. These risks can often be ambiguous or uncertain. In this dissertation, I study how consumers respond to ambiguity in pharmaceutical risk. I also examine two areas where risk is either not directly regulated or is perceived to be insufficiently regulated—I study whether patients, physicians, and third-party payers are sensitive to these risks or whether further regulation would be preferable. This dissertation begins by using an incentivized experiment to empirically estimate participants’ reactions to ambiguity in risks that a
drug is unsafe or ineffective in the presence of framing effects. The experiment finds that attitudes toward ambiguity are sensitive to risk type and framing effects. The dissertation then concentrates on two areas where risk is not directly regulated: The second chapter studies narrow therapeutic index drugs, drugs for which the generic approval process has been suspected to be inadequate in ensuring therapeutic equivalence. It finds evidence of a price penalty for the extra risk associated with NTI drugs. The third chapter studies off-label uses—the
prescription of a
drug for an unapproved use—and examines whether inappropriate off-label uses are relinquished even in the absence of direct FDA regulation. It finds evidence that relinquishment of off-label uses can be spurred by False Claims Act suits. The dissertation provides insight into areas in which parties seem sensitive to risk absent regulation and those in which further regulation may be necessary.
Advisors/Committee Members: Dr. Melinda J. Beeuwkes Buntin (committee member), James Blumstein (committee member), Dr. Daniel Gervais (committee member), Dr. W. Kip Viscusi (Committee Chair).
Subjects/Keywords: health; prescription drug; ambiguity; off-label; behavioral; risk
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Philip Gentry, A. E. (2016). Safety and Effectiveness: The FDA’s Approach to Risk in Prescription Medication. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/12003
Chicago Manual of Style (16th Edition):
Philip Gentry, Anne Elissa. “Safety and Effectiveness: The FDA’s Approach to Risk in Prescription Medication.” 2016. Doctoral Dissertation, Vanderbilt University. Accessed February 28, 2021.
http://hdl.handle.net/1803/12003.
MLA Handbook (7th Edition):
Philip Gentry, Anne Elissa. “Safety and Effectiveness: The FDA’s Approach to Risk in Prescription Medication.” 2016. Web. 28 Feb 2021.
Vancouver:
Philip Gentry AE. Safety and Effectiveness: The FDA’s Approach to Risk in Prescription Medication. [Internet] [Doctoral dissertation]. Vanderbilt University; 2016. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/1803/12003.
Council of Science Editors:
Philip Gentry AE. Safety and Effectiveness: The FDA’s Approach to Risk in Prescription Medication. [Doctoral Dissertation]. Vanderbilt University; 2016. Available from: http://hdl.handle.net/1803/12003

Penn State University
22.
Crowley, Daniel Max.
Evaluating The Cost-effectivness Of Real-world Prevention: Approaches For Estimating The Efficieny Of Evidence-based Programming.
Degree: 2012, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/15529
► Successful demonstrations of evidence-based preventative interventions (EBPIs) have led to a growing interest in prevention’s capacity to reduce major public health problems with greater efficiency.…
(more)
▼ Successful demonstrations of evidence-based preventative interventions (EBPIs) have led to a growing interest in prevention’s capacity to reduce major public health problems with greater efficiency. In response—just as prevention scientists once distinguished between the efficacy and effectiveness of prevention programs—now researchers are considering the distinction between program effectiveness and efficiency (i.e., contextualizing impact in terms of cost). This inquiry into the benefits and costs of EBPIs presents an opportunity to demonstrate prevention’s impact as well as its greater value to society. To accurately evaluate the efficiency of prevention efforts, program cost-effectiveness must be gauged in real-world contexts. In turn, new methodological approaches are needed to account for potential confounders that may reduce researcher’s ability to draw causal inferences about program impact. For instance, selection bias is introduced when local communities adopt one program over another and when the decision to enroll in multiple programs is left up to participants.
This work demonstrates an innovative approach for assessing the efficiency of evidence-based preventive interventions delivered in everyday settings. Using data from the PROSPER dissemination trial (over 12,000 youth; 28 Communities), this project applies propensity and marginal structural models to strengthen causal inference within cost-effectiveness analyses of community prevention efforts. Using these analytic techniques, I evaluated the effectiveness and cost-effectiveness of three school programs (Life Skills Training, All Stars and Project Alert) and a family program (SFP 10-14) to reduce
prescription opioid misuse (e.g., Vicodin, OxyContin). Findings indicated that universal school-based EBPIs can on their own reduce
prescription opioid misuse in a cost-effective manner and that the efficiency of a prevention effort employing such school programs can be enhanced by deploying an additional family-based program.
This methodological approach provides an opportunity to increase the relevance of prevention impact analyses by allowing researchers to better contextualize program effectiveness in terms of program costs. Specifically, this method provides a more refined approach for understanding the impact of combining interventions and may expedite the development of more efficient prevention efforts. Further, analyses such as these can provide important information to not only researchers, but to multiple stakeholders who seek to translate prevention science into practice.
Advisors/Committee Members: Mark T Greenberg, Dissertation Advisor/Co-Advisor, Mark T Greenberg, Committee Chair/Co-Chair, Damon Evan Jones, Committee Chair/Co-Chair, Linda Marie Collins, Committee Member, Edward A Smith, Committee Member, Donna Coffman, Committee Member, Daniel Francis Perkins, Special Member, Steven Howard Zarit, Special Member.
Subjects/Keywords: Prevention Science; Cost-Effectiveness; Prescription Drug Misuse; Efficiency Analyses
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Crowley, D. M. (2012). Evaluating The Cost-effectivness Of Real-world Prevention: Approaches For Estimating The Efficieny Of Evidence-based Programming. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/15529
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Crowley, Daniel Max. “Evaluating The Cost-effectivness Of Real-world Prevention: Approaches For Estimating The Efficieny Of Evidence-based Programming.” 2012. Thesis, Penn State University. Accessed February 28, 2021.
https://submit-etda.libraries.psu.edu/catalog/15529.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Crowley, Daniel Max. “Evaluating The Cost-effectivness Of Real-world Prevention: Approaches For Estimating The Efficieny Of Evidence-based Programming.” 2012. Web. 28 Feb 2021.
Vancouver:
Crowley DM. Evaluating The Cost-effectivness Of Real-world Prevention: Approaches For Estimating The Efficieny Of Evidence-based Programming. [Internet] [Thesis]. Penn State University; 2012. [cited 2021 Feb 28].
Available from: https://submit-etda.libraries.psu.edu/catalog/15529.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Crowley DM. Evaluating The Cost-effectivness Of Real-world Prevention: Approaches For Estimating The Efficieny Of Evidence-based Programming. [Thesis]. Penn State University; 2012. Available from: https://submit-etda.libraries.psu.edu/catalog/15529
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Washington State University
23.
[No author].
Pills, Patches, and Syrups, Oh My: An Exploratory Study of College Men's and Women's Non-Medical Prescription Drug Use
.
Degree: 2013, Washington State University
URL: http://hdl.handle.net/2376/4799
► National surveys on substance use indicate that the prevalence of non-medical prescription drug use is now greater than the prevalence of illicit drugs other than…
(more)
▼ National surveys on substance use indicate that the prevalence of non-medical prescription drug use is now greater than the prevalence of illicit drugs other than marijuana (National Survey on Drug Use and Health 2008). Of the persons misusing prescription drugs, young adults, aged 18-25 report the highest prevalence of misuse, with males and females misusing these drugs at comparable rates. This absence of a gender-gap in the misuse of prescription drugs runs counter to data on the misuse and abuse of illicit drugs (e.g., cocaine, ecstasy and heroin) and on problem alcohol use which indicate that men use and abuse these substances at a much higher rate than women. Studies on prescription drug use also indicate that being a college student is a risk factor for prescription drug abuse and misuse and show that on the most "prescription prone" college campuses 1 in 4 students are misusing prescription drugs (McCabe, Boyd, and Teter, 2006). This study provides an in-depth analysis of college men's and women's opportunities, motivations and justifications for non-medical prescription drug use. Qualitative methodological techniques were used in the form of semi-structured, open-ended interviews with individuals 18-25 years of age attending a large, public University in the Northwest. The analyses are informed by social learning, sub-cultural, and gendered theories of offending that emphasize the importance of learned motives and techniques of acquiring and appropriately using prescription drugs. Gender similarities and differences in key aspects of the "context of offending" are also identified including reasons for using prescription drugs, opportunities and methods for obtaining these drugs and diversion efforts.
Subjects/Keywords: Sociology;
college students;
drug use;
gender;
prescription drugs
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APA (6th Edition):
author], [. (2013). Pills, Patches, and Syrups, Oh My: An Exploratory Study of College Men's and Women's Non-Medical Prescription Drug Use
. (Thesis). Washington State University. Retrieved from http://hdl.handle.net/2376/4799
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
author], [No. “Pills, Patches, and Syrups, Oh My: An Exploratory Study of College Men's and Women's Non-Medical Prescription Drug Use
.” 2013. Thesis, Washington State University. Accessed February 28, 2021.
http://hdl.handle.net/2376/4799.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
author], [No. “Pills, Patches, and Syrups, Oh My: An Exploratory Study of College Men's and Women's Non-Medical Prescription Drug Use
.” 2013. Web. 28 Feb 2021.
Vancouver:
author] [. Pills, Patches, and Syrups, Oh My: An Exploratory Study of College Men's and Women's Non-Medical Prescription Drug Use
. [Internet] [Thesis]. Washington State University; 2013. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/2376/4799.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
author] [. Pills, Patches, and Syrups, Oh My: An Exploratory Study of College Men's and Women's Non-Medical Prescription Drug Use
. [Thesis]. Washington State University; 2013. Available from: http://hdl.handle.net/2376/4799
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of New Mexico
24.
Callan, Danelle.
Medicare Part D Coverage Gap: Who Falls In and What Beneficiaries Do to Avoid Entry.
Degree: Department of Economics, 2012, University of New Mexico
URL: http://hdl.handle.net/1928/20313
► In 2006, the implementation of Medicare Part D offered seniors the benefit of government subsidized prescription drug coverage. The baby boomer generation is expected to…
(more)
▼ In 2006, the implementation of Medicare Part D offered seniors the benefit of government subsidized
prescription drug coverage. The baby boomer generation is expected to retire at a rate of 10,000 per day for the next nineteen years. Research into health care and
prescription drug coverage for this aging population is becoming relevant due to a increasing proportion of the population. Understanding the characteristics of individuals who reach the Medicare Part D coverage gap will assist in possible outreach, education, and future enrollment strategies. Identifying populations at risk of reaching the coverage gap can help focus interventions to address issues of access to medication among seniors. This research project considers the previous literature published on beneficiaries who reached the aforementioned coverage gap where beneficiaries pay one hundred percent of
prescription costs and applies it to a larger, more comprehensive data set. First, I identify characteristics of Part D individuals that influence the outcome of reaching the coverage gap. Then, I assess the effect a coverage gap has on
drug adherence by analyzing out of pocket expenditures.
Advisors/Committee Members: Blume-Kohout, Margaret, Moffett, Maurice, Fontenla, Matias, Moffett, Maurice, Blume-Kohout, Margaret.
Subjects/Keywords: Medicare Part D; Economics; Health Economics; Prescription drug coverage; Doughnut hole
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APA ·
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MLA ·
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Manager
APA (6th Edition):
Callan, D. (2012). Medicare Part D Coverage Gap: Who Falls In and What Beneficiaries Do to Avoid Entry. (Masters Thesis). University of New Mexico. Retrieved from http://hdl.handle.net/1928/20313
Chicago Manual of Style (16th Edition):
Callan, Danelle. “Medicare Part D Coverage Gap: Who Falls In and What Beneficiaries Do to Avoid Entry.” 2012. Masters Thesis, University of New Mexico. Accessed February 28, 2021.
http://hdl.handle.net/1928/20313.
MLA Handbook (7th Edition):
Callan, Danelle. “Medicare Part D Coverage Gap: Who Falls In and What Beneficiaries Do to Avoid Entry.” 2012. Web. 28 Feb 2021.
Vancouver:
Callan D. Medicare Part D Coverage Gap: Who Falls In and What Beneficiaries Do to Avoid Entry. [Internet] [Masters thesis]. University of New Mexico; 2012. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/1928/20313.
Council of Science Editors:
Callan D. Medicare Part D Coverage Gap: Who Falls In and What Beneficiaries Do to Avoid Entry. [Masters Thesis]. University of New Mexico; 2012. Available from: http://hdl.handle.net/1928/20313

University of Minnesota
25.
Kim, Jee-Ae.
Medication Utilization of Dual Eligibles Before and After Medicare Part D: Cases of Antidepressants and Antipsychotics.
Degree: PhD, Health Services Research, Policy and Administration, 2014, University of Minnesota
URL: http://hdl.handle.net/11299/182292
► Objectives: The study objective is to examine whether medication utilization among dual eligibles was different under Part D compared to Medicaid period by focusing on…
(more)
▼ Objectives: The study objective is to examine whether medication utilization among dual eligibles was different under Part D compared to Medicaid period by focusing on states which vary baseline state Medicaid policies and wrap-around programs for dual eligibles to access drugs under Part D. The transition of prescription drug benefits to federal Medicare Part D from state Medicaid has potential to affect medication utilization for dual eligibles, beneficiaries for both Medicaid and Medicare programs. Changes in prescription drug benefits under Part D will not equally affect the dual eligible and will differ by states with differences in baseline Medicaid policies and availability of wrap-around programs to access drugs under Part D. The study focuses on antidepressants and antipsychotics. Methods: This study is a pre-post study design with a longitudinal dataset by linking Medicaid data for 2004-2005 and 5% random sample of Medicare data for 2006-2007. The study population is dual eligibles, existing users of antidepressants and of antipsychotics in 2004 and with enrollment from 2004-2007 in eight states. I employ a state-fixed effect model to estimate medication utilization using proportion of days covered (PDC), adjusting for beneficiaries characteristics and health status. I adopt generalized estimation equation (GEE) model for estimating PDC and spline regression for investigating whether changes in PDCs were related to Part D. A stratified analysis is conducted for community based dual eligibles (n=4,703 for antidepressants, n=2,301 for antipsychotics) and nursing home dual eligibles (n=1,504 for antidepressants, n=1,011 for antipsychotics) separately. Results: For antidepressants, adjusted changes in PDC were not significant for most states, except Arkansas community based dual eligibles (p=0.00), Florida nursing home dual eligibles had a significant increase (p=0.03), New Mexico nursing home dual eligibles(p=0.01) under Part D. For antipsychotics, adjusted changes in PDC were not significant in all states except Arkansas community based dual eligibles (p=0.03) and Florida for both groups (p=0.00 for both community based dual eligibles and nursing home dual eligibles). A separate spline regression for states that had significant changes in PDC from the state-fixed effect model indicated that trends in PDC before and after Part D were not significantly different, suggesting that changes were not related to transition to Part D. Conclusions: I did not find empirical support for concerns regarding disruption of medication utilization of the dual eligible under Part D. Although states had different baseline Medicaid polices and wrap-around programs under Part D, lack of significant changes in utilization suggest that minor changes in copayments and refill/prescription limits etc. do not have large effect on medication utilization to antidepressants and antipsychotics.
Subjects/Keywords: Antidepressants; Antipsychotics; Dual Eligibles; Medicaid; Medicare Part D; Prescription Drug program
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kim, J. (2014). Medication Utilization of Dual Eligibles Before and After Medicare Part D: Cases of Antidepressants and Antipsychotics. (Doctoral Dissertation). University of Minnesota. Retrieved from http://hdl.handle.net/11299/182292
Chicago Manual of Style (16th Edition):
Kim, Jee-Ae. “Medication Utilization of Dual Eligibles Before and After Medicare Part D: Cases of Antidepressants and Antipsychotics.” 2014. Doctoral Dissertation, University of Minnesota. Accessed February 28, 2021.
http://hdl.handle.net/11299/182292.
MLA Handbook (7th Edition):
Kim, Jee-Ae. “Medication Utilization of Dual Eligibles Before and After Medicare Part D: Cases of Antidepressants and Antipsychotics.” 2014. Web. 28 Feb 2021.
Vancouver:
Kim J. Medication Utilization of Dual Eligibles Before and After Medicare Part D: Cases of Antidepressants and Antipsychotics. [Internet] [Doctoral dissertation]. University of Minnesota; 2014. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/11299/182292.
Council of Science Editors:
Kim J. Medication Utilization of Dual Eligibles Before and After Medicare Part D: Cases of Antidepressants and Antipsychotics. [Doctoral Dissertation]. University of Minnesota; 2014. Available from: http://hdl.handle.net/11299/182292

University of Hawaii – Manoa
26.
Roberson, Emily Kathleen.
Using pregnancy risk assessment monitoring system data to investigate prescription drug use during pregnancy in Hawaiʻi.
Degree: 2015, University of Hawaii – Manoa
URL: http://hdl.handle.net/10125/100473
► Ph.D. University of Hawaii at Manoa 2014.
Both legal and illicit use of prescription drugs during pregnancy is thought to be increasingly common in the…
(more)
▼ Ph.D. University of Hawaii at Manoa 2014.
Both legal and illicit use of prescription drugs during pregnancy is thought to be increasingly common in the state of Hawaiʻi, based on trends demonstrated elsewhere in the country and throughout the world. Prescription opioids, along with antianxiety and antidepressant medications are of special concern, both for their prevalence and for the potential risks associated with using these drugs during pregnancy.
The purpose of this dissertation is to investigate prescription drug use during pregnancy in Hawaiʻi, with a focus on opioids and antianxiety and antidepressant medications. The first of three studies sought to determine the prevalence of prescription opioid drug use during pregnancy in Hawaiʻi, describe differences in prescription opioid drug use during pregnancy in Hawaiʻi by maternal demographic characteristics, and investigate possible predictors of prescription opioid drug use during pregnancy through the use of multivariable logistic regression. The second study aimed to determine whether prescription opioid use during pregnancy was associated with poorer birth outcomes among users when compared to non-users in Hawaiʻi; specifically focusing on associations between prescription opioid use during pregnancy and risk of small for gestational age, preterm, or low birth weight deliveries among women giving birth to live, singleton infants in Hawaiʻi. Study three attempted to describe the under-studied topics of anxiety and depression before, during, and after pregnancy, along with related help-seeking behaviors and treatment strategies, for which there is a scarcity of information in Hawaiʻi.
Findings from the three studies covered in this dissertation confirm that use of prescription opioids and antianxiety and antidepressant medications is relatively common during pregnancy in Hawaiʻi. They also provide more detailed information on usage patterns, differences by demographic characteristics, and associated risk factors and birth and maternal health outcomes. All three also provide suggestions for future research avenues in order to more fully understand the complete landscape of prescription drug use during pregnancy in Hawaiʻi.
Subjects/Keywords: Opioids; Prescription drug use; Pregnancy; Birth outcomes; Depression; Anxiety
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Roberson, E. K. (2015). Using pregnancy risk assessment monitoring system data to investigate prescription drug use during pregnancy in Hawaiʻi. (Thesis). University of Hawaii – Manoa. Retrieved from http://hdl.handle.net/10125/100473
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Roberson, Emily Kathleen. “Using pregnancy risk assessment monitoring system data to investigate prescription drug use during pregnancy in Hawaiʻi.” 2015. Thesis, University of Hawaii – Manoa. Accessed February 28, 2021.
http://hdl.handle.net/10125/100473.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Roberson, Emily Kathleen. “Using pregnancy risk assessment monitoring system data to investigate prescription drug use during pregnancy in Hawaiʻi.” 2015. Web. 28 Feb 2021.
Vancouver:
Roberson EK. Using pregnancy risk assessment monitoring system data to investigate prescription drug use during pregnancy in Hawaiʻi. [Internet] [Thesis]. University of Hawaii – Manoa; 2015. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/10125/100473.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Roberson EK. Using pregnancy risk assessment monitoring system data to investigate prescription drug use during pregnancy in Hawaiʻi. [Thesis]. University of Hawaii – Manoa; 2015. Available from: http://hdl.handle.net/10125/100473
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
27.
Mazer-Amirshahi, Maryann.
Prescription Drug Shortages: Implications for Public Health and Potential Solutions.
Degree: 2019, Erasmus University Medical Center
URL: http://hdl.handle.net/1765/116728
► markdownabstractPrescription drug shortages have reached critical levels in the United States and represent a significant threat to healthcare quality and patient safety. The increase in…
(more)
▼ markdownabstractPrescription drug shortages have reached critical levels in the United States and represent a significant threat to healthcare quality and patient safety. The increase in drug shortages has been attributed to a variety of factors, although some underlying themes prevail, primarily quality problems at manufacturing facilities. Market factors also play a significant role. Sterile generic injectable medications have been disproportionately impacted by drug shortages.
This thesis is intended to explore the impacts of drug shortages across a wide range of specialties, care settings, and populations. This work will describe trends in drug shortages over time and the potential implications for patient care and public health. It also addresses current and proposed initiatives to mitigate this public health threat.
Subjects/Keywords: Prescription drug shortages; public health
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mazer-Amirshahi, M. (2019). Prescription Drug Shortages: Implications for Public Health and Potential Solutions. (Doctoral Dissertation). Erasmus University Medical Center. Retrieved from http://hdl.handle.net/1765/116728
Chicago Manual of Style (16th Edition):
Mazer-Amirshahi, Maryann. “Prescription Drug Shortages: Implications for Public Health and Potential Solutions.” 2019. Doctoral Dissertation, Erasmus University Medical Center. Accessed February 28, 2021.
http://hdl.handle.net/1765/116728.
MLA Handbook (7th Edition):
Mazer-Amirshahi, Maryann. “Prescription Drug Shortages: Implications for Public Health and Potential Solutions.” 2019. Web. 28 Feb 2021.
Vancouver:
Mazer-Amirshahi M. Prescription Drug Shortages: Implications for Public Health and Potential Solutions. [Internet] [Doctoral dissertation]. Erasmus University Medical Center; 2019. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/1765/116728.
Council of Science Editors:
Mazer-Amirshahi M. Prescription Drug Shortages: Implications for Public Health and Potential Solutions. [Doctoral Dissertation]. Erasmus University Medical Center; 2019. Available from: http://hdl.handle.net/1765/116728

University of Georgia
28.
Williams, Chakita Kenyotta.
Applying a model of risk information seeking to a newly discovered drug risk.
Degree: 2014, University of Georgia
URL: http://hdl.handle.net/10724/28628
► Information seeking and processing behaviors among people with type 2 diabetes about a drug’s risk, such as rosiglitazone cardiovascular risk, motivated this dissertation. To my…
(more)
▼ Information seeking and processing behaviors among people with type 2 diabetes about a drug’s risk, such as rosiglitazone cardiovascular risk, motivated this dissertation. To my knowledge, this study was the first to investigate this issue
in the context of a drug risk that was discovered after a FDA approved drug was widely prescribed to individuals. The main purpose of the study was to determine predictors of health information seeking and processing among people with type 2 diabetes in
regard to rosiglitazone’s’ cardiovascular risk. The study seeks to accomplish this by applying the Risk Information Seeking and Processing model to a drug risk that was identified after the drug had been prescribed to millions of people. The study tested
hypotheses regarding the relationship between information insufficiency (the difference between knowledge held and knowledge needed about the risk), channel beliefs (TV news, newspapers, magazines), perceived information gathering capacity and their
seeking and processing of information on rosiglitazone’s cardiovascular risk. A quantitative online survey guided the data collection. A sample of 259 people with diabetes, provided by Qualtrics, was involved in the study. Respondents completed a
questionnaire with items that were adapted from previously published studies using the Risk Information Seeking and Processing Model. Hierarchical regression analysis was used to analyze the data. The findings suggest that the Risk Information Seeking
and Processing Model remains applicable to a newly discovered drug risk like that of rosiglitazone cardiovascular risk. The results revealed that channel beliefs and perceived information gathering capacity are promising cognitive factors that risk
communicators can influence in an attempt to improve information seeking and processing.
Subjects/Keywords: Prescription drug; medication risk; risk communication; information seeking; information processing
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Williams, C. K. (2014). Applying a model of risk information seeking to a newly discovered drug risk. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/28628
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Williams, Chakita Kenyotta. “Applying a model of risk information seeking to a newly discovered drug risk.” 2014. Thesis, University of Georgia. Accessed February 28, 2021.
http://hdl.handle.net/10724/28628.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Williams, Chakita Kenyotta. “Applying a model of risk information seeking to a newly discovered drug risk.” 2014. Web. 28 Feb 2021.
Vancouver:
Williams CK. Applying a model of risk information seeking to a newly discovered drug risk. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/10724/28628.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Williams CK. Applying a model of risk information seeking to a newly discovered drug risk. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/28628
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Georgia
29.
Huh, Jisu.
Perceived effects, mediating influences, and behavioral outcomes of direct-to-consumer prescription drug advertising.
Degree: 2014, University of Georgia
URL: http://hdl.handle.net/10724/21069
► Direct-to-consumer prescription drug advertising (DTCAd) is a growing, yet unique form of product advertising about which research evidence is emerging. This dissertation was undertaken to…
(more)
▼ Direct-to-consumer prescription drug advertising (DTCAd) is a growing, yet unique form of product advertising about which research evidence is emerging. This dissertation was undertaken to explore questions about perceived DTCAd effects and
the relationships of those perceptions and other perceptual, attitudinal, and demographic variables to two specific behavioral outcomes (support for regulation and patient behaviors), using the third-person effect framework. A mail survey of 600 randomly
selected adults was executed to address nine hypotheses and three research questions. 264 useable questionnaires were returned. Among other things, the research found: •The third-person DTCAd effect is a multidimensional construct. Four DTCAd-effect
factors emerged from respondents’ perceptions of DTCAd effects. •Respondents believed that DTCAd had more influence on other people’s behavior than on their own behavior. •Respondents differentiated between the negative and positive DTCAd effects, and
perceived negative DTCAd effects to be more pronounced in other people’s behavior than in their own behavior. •Perceived DTCAd importance, prescription drug use, perceived DTCAd credibility/informativeness, and global DTCAd attitude were negatively
associated with third-person DTCAd effects. •Perceived health and DTCAd recognition were positively associated with third-person DTCAd effects. •Ability of the third-person DTCAd effect to predict support for DTCAd regulation did not vary by global DTCAd
attitude. When global DTCAd attitude was controlled for, third-person DTCAd effects did not predict support for DTCAd regulation. •Older, employed, less educated respondents, who disliked DTCAd, but who perceived themselves more familiar and
knowledgeable of DTCAd were more likely to support DTCAd regulation. Those who perceived DTCAd as credible were less likely to support DTCAd regulation. •The third-person effect associated with the DTCAd factor, "learning & involvement," was a
significant negative predictor of patient behavior. •Perceived DTCAd importance and respondent race were significant positive predictors of patient behavior. •Ability of third-person DTCAd effects to predict DTCAd-targeted patient behavior did not vary
by respondents’ global DTCAd attitudes. No matter how much the respondents liked or disliked DTCAd, those who perceived greater third-person DTCAd effects were less likely to engage in ad-targeted patient behaviors. The significance of the results is
discussed relative to the research literature. Methodological imitations are presented, followed by implications for advancing DTCAd research.
Subjects/Keywords: DTC prescription drug advertising; third-person effect; advertising effects; pharmaceutical advertising
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Huh, J. (2014). Perceived effects, mediating influences, and behavioral outcomes of direct-to-consumer prescription drug advertising. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/21069
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Huh, Jisu. “Perceived effects, mediating influences, and behavioral outcomes of direct-to-consumer prescription drug advertising.” 2014. Thesis, University of Georgia. Accessed February 28, 2021.
http://hdl.handle.net/10724/21069.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Huh, Jisu. “Perceived effects, mediating influences, and behavioral outcomes of direct-to-consumer prescription drug advertising.” 2014. Web. 28 Feb 2021.
Vancouver:
Huh J. Perceived effects, mediating influences, and behavioral outcomes of direct-to-consumer prescription drug advertising. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/10724/21069.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Huh J. Perceived effects, mediating influences, and behavioral outcomes of direct-to-consumer prescription drug advertising. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/21069
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Georgia
30.
Cantrell, Christopher Ron.
Development and validation of risk assessment models to predict pharmacy expenditures for both commercial and medicaid populations.
Degree: 2014, University of Georgia
URL: http://hdl.handle.net/10724/21448
► Numerous risk assessment models have been developed to predict overall healthcare costs, utilization, mortality and hospital length of stay, however, there have been no models…
(more)
▼ Numerous risk assessment models have been developed to predict overall healthcare costs, utilization, mortality and hospital length of stay, however, there have been no models to date developed specifically to predict prescription
expenditures. The objective of this research was to empirically develop a claims-based risk assessment model to predict prescription expenditures for both a commercial and Medicaid population. The models were developed using three years, 1998 through
2000, of MEDSTAT MarketScan data (commercial) and California Medicaid data (Medicaid). Both datasets are claims-based data that include medical and pharmacy claims and enrollment information in a linkable format. The MarketScan training sample used to
develop the commercial models included over 1.3 million lives after the inclusion/exclusion criteria were satisfied. The California Medicaid (MediCal) training sample used to develop the Medicaid models included over 138 thousand lives after the
inclusion/exclusion criteria were satisfied. A random sample of each dataset was used to validate the models. Ordinary Least Squares (OLS) was utilized to estimate the model coefficients. The primary model for this research, the Rx Cost Model (RxCost),
is a diagnostic-based model that was empirically developed using diagnostic information. Another model, the Mixed Rx Cost Model (MRxCost), is a diagnostic and drug-based model that was developed to explore the gain in predictive power of supplementing
the RxCost Model with drug information. The MarketScan validation sample was utilized to compare the performance of the models developed for the commercial population to each other as well as a Demographic-only model and the commercially available
DCG-HCC model. The MediCal validation sample was used to compare the performance of the models developed for the Medicaid population to each other as well as a Demographic-only model, a Demographic and Medicaid eligibility model and the CDPS model. The
R-square values for the commercial RxCost Model, the MRxCost Model and the DCG-HCC using the validation sample were 0.22, 0.34 and 0.16 respectively. The R-square values for the Medicaid RxCost Model, the MRxCost Model and the CDPS using the validation
sample were 0.24, 0.30 and 0.04 respectively. The RxCost Model for both the commercial and Medicaid population performed better then the DCG-HCC and the CDPS in terms of R-square. The MRxCost Model for each population also performed well and resulted in
a substantial gain of predictive power in terms of R-square.
Subjects/Keywords: Risk Assessment; Risk Adjustment; Prescription Cost; Drug Cost; Risk Models
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Cantrell, C. R. (2014). Development and validation of risk assessment models to predict pharmacy expenditures for both commercial and medicaid populations. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/21448
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Cantrell, Christopher Ron. “Development and validation of risk assessment models to predict pharmacy expenditures for both commercial and medicaid populations.” 2014. Thesis, University of Georgia. Accessed February 28, 2021.
http://hdl.handle.net/10724/21448.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Cantrell, Christopher Ron. “Development and validation of risk assessment models to predict pharmacy expenditures for both commercial and medicaid populations.” 2014. Web. 28 Feb 2021.
Vancouver:
Cantrell CR. Development and validation of risk assessment models to predict pharmacy expenditures for both commercial and medicaid populations. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Feb 28].
Available from: http://hdl.handle.net/10724/21448.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Cantrell CR. Development and validation of risk assessment models to predict pharmacy expenditures for both commercial and medicaid populations. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/21448
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
◁ [1] [2] [3] [4] [5] [6] ▶
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