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University: University of Michigan

You searched for subject:(Drug delivery). Showing records 1 – 30 of 30 total matches.

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University of Michigan

1. Rabinsky, Emily F. Effect of Protein Coatings on the Delivery Performance of Liposomes.

Degree: PhD, Pharmaceutical Sciences, 2011, University of Michigan

 Modifications of the surface properties of liposomal drug carriers, such as coating with therapeutic or targeting proteins, greatly impact their delivery performance. Many of the… (more)

Subjects/Keywords: Liposomes; Drug Delivery; Vaccine; Apolipoprotein B; Pharmacy and Pharmacology; Health Sciences

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APA (6th Edition):

Rabinsky, E. F. (2011). Effect of Protein Coatings on the Delivery Performance of Liposomes. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/86502

Chicago Manual of Style (16th Edition):

Rabinsky, Emily F. “Effect of Protein Coatings on the Delivery Performance of Liposomes.” 2011. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/86502.

MLA Handbook (7th Edition):

Rabinsky, Emily F. “Effect of Protein Coatings on the Delivery Performance of Liposomes.” 2011. Web. 19 Mar 2019.

Vancouver:

Rabinsky EF. Effect of Protein Coatings on the Delivery Performance of Liposomes. [Internet] [Doctoral dissertation]. University of Michigan; 2011. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/86502.

Council of Science Editors:

Rabinsky EF. Effect of Protein Coatings on the Delivery Performance of Liposomes. [Doctoral Dissertation]. University of Michigan; 2011. Available from: http://hdl.handle.net/2027.42/86502


University of Michigan

2. Shirakura, Teppei. Development of Drug-loaded Nanoparticles for Targeted Chemotherapy.

Degree: PhD, Biophysics, 2015, University of Michigan

 Cancer is the second highest cause of death in the US, and chemotherapy is one of the common cancer therapies. In order to reduce side… (more)

Subjects/Keywords: drug delivery system; chemotherapy; cancer; nanoparticle; cisplatin; Biomedical Engineering; Health Sciences

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APA (6th Edition):

Shirakura, T. (2015). Development of Drug-loaded Nanoparticles for Targeted Chemotherapy. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/111622

Chicago Manual of Style (16th Edition):

Shirakura, Teppei. “Development of Drug-loaded Nanoparticles for Targeted Chemotherapy.” 2015. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/111622.

MLA Handbook (7th Edition):

Shirakura, Teppei. “Development of Drug-loaded Nanoparticles for Targeted Chemotherapy.” 2015. Web. 19 Mar 2019.

Vancouver:

Shirakura T. Development of Drug-loaded Nanoparticles for Targeted Chemotherapy. [Internet] [Doctoral dissertation]. University of Michigan; 2015. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/111622.

Council of Science Editors:

Shirakura T. Development of Drug-loaded Nanoparticles for Targeted Chemotherapy. [Doctoral Dissertation]. University of Michigan; 2015. Available from: http://hdl.handle.net/2027.42/111622


University of Michigan

3. Chen, Junjie. Aggregation and Dendrimer Mediated Secondary Binding towards Folate Binding Protein & Fatigue Failure Mechanism of Anterior Cruciate Ligament Fracture.

Degree: PhD, Chemistry, 2018, University of Michigan

Drug conjugation gives many advantages such as improved targeting, solubility and retention. How conjugated drugs interact with proteins is a key question to answer in… (more)

Subjects/Keywords: dendrimer drug delivery; anterior cruciate ligament injury; nanoparticle aggregation; Chemistry; Science

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APA (6th Edition):

Chen, J. (2018). Aggregation and Dendrimer Mediated Secondary Binding towards Folate Binding Protein & Fatigue Failure Mechanism of Anterior Cruciate Ligament Fracture. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/144055

Chicago Manual of Style (16th Edition):

Chen, Junjie. “Aggregation and Dendrimer Mediated Secondary Binding towards Folate Binding Protein & Fatigue Failure Mechanism of Anterior Cruciate Ligament Fracture.” 2018. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/144055.

MLA Handbook (7th Edition):

Chen, Junjie. “Aggregation and Dendrimer Mediated Secondary Binding towards Folate Binding Protein & Fatigue Failure Mechanism of Anterior Cruciate Ligament Fracture.” 2018. Web. 19 Mar 2019.

Vancouver:

Chen J. Aggregation and Dendrimer Mediated Secondary Binding towards Folate Binding Protein & Fatigue Failure Mechanism of Anterior Cruciate Ligament Fracture. [Internet] [Doctoral dissertation]. University of Michigan; 2018. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/144055.

Council of Science Editors:

Chen J. Aggregation and Dendrimer Mediated Secondary Binding towards Folate Binding Protein & Fatigue Failure Mechanism of Anterior Cruciate Ligament Fracture. [Doctoral Dissertation]. University of Michigan; 2018. Available from: http://hdl.handle.net/2027.42/144055


University of Michigan

4. Rahmani, Sahar. Multifunctional Drug Carriers with Programmable Properties.

Degree: PhD, Biomedical Engineering, 2015, University of Michigan

 In recent decades, drug-loaded carrier systems have become a viable option to replace or augment current, unsuccessful therapies that address a myriad of disease conditions.… (more)

Subjects/Keywords: Drug Delivery; Electrohydrodynamic co-jetting (EHD); Patchy Particles; Cochlear Delivery; Multifunctional Particles; Functional Polymers; Biomedical Engineering; Engineering

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APA (6th Edition):

Rahmani, S. (2015). Multifunctional Drug Carriers with Programmable Properties. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/111636

Chicago Manual of Style (16th Edition):

Rahmani, Sahar. “Multifunctional Drug Carriers with Programmable Properties.” 2015. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/111636.

MLA Handbook (7th Edition):

Rahmani, Sahar. “Multifunctional Drug Carriers with Programmable Properties.” 2015. Web. 19 Mar 2019.

Vancouver:

Rahmani S. Multifunctional Drug Carriers with Programmable Properties. [Internet] [Doctoral dissertation]. University of Michigan; 2015. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/111636.

Council of Science Editors:

Rahmani S. Multifunctional Drug Carriers with Programmable Properties. [Doctoral Dissertation]. University of Michigan; 2015. Available from: http://hdl.handle.net/2027.42/111636


University of Michigan

5. Zou, Peng. "Nanotheranostics" for Tumor Imaging and Targeted Drug Delivery.

Degree: PhD, Pharmaceutical Sciences, 2011, University of Michigan

 The magnetic resonance imaging (MRI) technique is a promising tool that improves cancer detection, facilitates diagnosis and monitors therapeutic effects. Superparamagnetic iron oxide nanoparticles (SPIOs)… (more)

Subjects/Keywords: Iron Oxide; Nanoparticle; Polymeric Micelle; Premature Drug Release; Targeted Drug Delivery; Fluorescence Resonance Energy Transfer Imaging; Pharmacy and Pharmacology; Health Sciences

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APA (6th Edition):

Zou, P. (2011). "Nanotheranostics" for Tumor Imaging and Targeted Drug Delivery. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/89782

Chicago Manual of Style (16th Edition):

Zou, Peng. “"Nanotheranostics" for Tumor Imaging and Targeted Drug Delivery.” 2011. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/89782.

MLA Handbook (7th Edition):

Zou, Peng. “"Nanotheranostics" for Tumor Imaging and Targeted Drug Delivery.” 2011. Web. 19 Mar 2019.

Vancouver:

Zou P. "Nanotheranostics" for Tumor Imaging and Targeted Drug Delivery. [Internet] [Doctoral dissertation]. University of Michigan; 2011. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/89782.

Council of Science Editors:

Zou P. "Nanotheranostics" for Tumor Imaging and Targeted Drug Delivery. [Doctoral Dissertation]. University of Michigan; 2011. Available from: http://hdl.handle.net/2027.42/89782


University of Michigan

6. Nieto, Kari. Long-Acting Release Implants for Local Fenretinide Delivery and Oral Cancer Chemoprevention.

Degree: PhD, Pharmaceutical Sciences, 2017, University of Michigan

 The synthetic vitamin A derivative, fenretinide (4HPR) was developed in the 1970’s as a means to induce retinoid cancer preventive effects in cells and tissues… (more)

Subjects/Keywords: Local Drug Delivery; Oral Cancer Chemoprevention; Drug-Tissue Penetration Enhancement; Fenretinide; Long-Acting Release Implants; Science (General); Science

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APA (6th Edition):

Nieto, K. (2017). Long-Acting Release Implants for Local Fenretinide Delivery and Oral Cancer Chemoprevention. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/140855

Chicago Manual of Style (16th Edition):

Nieto, Kari. “Long-Acting Release Implants for Local Fenretinide Delivery and Oral Cancer Chemoprevention.” 2017. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/140855.

MLA Handbook (7th Edition):

Nieto, Kari. “Long-Acting Release Implants for Local Fenretinide Delivery and Oral Cancer Chemoprevention.” 2017. Web. 19 Mar 2019.

Vancouver:

Nieto K. Long-Acting Release Implants for Local Fenretinide Delivery and Oral Cancer Chemoprevention. [Internet] [Doctoral dissertation]. University of Michigan; 2017. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/140855.

Council of Science Editors:

Nieto K. Long-Acting Release Implants for Local Fenretinide Delivery and Oral Cancer Chemoprevention. [Doctoral Dissertation]. University of Michigan; 2017. Available from: http://hdl.handle.net/2027.42/140855


University of Michigan

7. Vaidyanathan, Sriram. Disruption of Endosomal Membrane by Cationic Vectors Drives Endosomal Release and Enables Successful Gene Delivery.

Degree: PhD, Biomedical Engineering, 2016, University of Michigan

 The potential of gene therapy to treat congenital disorders is hindered by the lack of safe and effective delivery agents (vectors). More effective viral vectors… (more)

Subjects/Keywords: Gene delivery; Gene therapy; Endosomal escape; Drug delivery; Proton sponge; siRNA delivery; Biomedical Engineering; Biological Chemistry; Chemistry; Science (General); Engineering; Health Sciences; Science

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APA (6th Edition):

Vaidyanathan, S. (2016). Disruption of Endosomal Membrane by Cationic Vectors Drives Endosomal Release and Enables Successful Gene Delivery. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/120751

Chicago Manual of Style (16th Edition):

Vaidyanathan, Sriram. “Disruption of Endosomal Membrane by Cationic Vectors Drives Endosomal Release and Enables Successful Gene Delivery.” 2016. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/120751.

MLA Handbook (7th Edition):

Vaidyanathan, Sriram. “Disruption of Endosomal Membrane by Cationic Vectors Drives Endosomal Release and Enables Successful Gene Delivery.” 2016. Web. 19 Mar 2019.

Vancouver:

Vaidyanathan S. Disruption of Endosomal Membrane by Cationic Vectors Drives Endosomal Release and Enables Successful Gene Delivery. [Internet] [Doctoral dissertation]. University of Michigan; 2016. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/120751.

Council of Science Editors:

Vaidyanathan S. Disruption of Endosomal Membrane by Cationic Vectors Drives Endosomal Release and Enables Successful Gene Delivery. [Doctoral Dissertation]. University of Michigan; 2016. Available from: http://hdl.handle.net/2027.42/120751


University of Michigan

8. Zhang, Zhanpeng. Advanced Microspheres as Injectable Cell Carriers for Tissue Engineering.

Degree: PhD, Biomedical Engineering, 2015, University of Michigan

 Biodegradable polymer microspheres have emerged as injectable cell carriers for the regeneration and repair of irregularly-shaped tissue defects. The physical structure and chemical composition of… (more)

Subjects/Keywords: tissue regeneration; cell carrier; stem cell; polymer self-assembly; biomimetic; drug delivery; Biomedical Engineering; Engineering

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APA (6th Edition):

Zhang, Z. (2015). Advanced Microspheres as Injectable Cell Carriers for Tissue Engineering. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/111559

Chicago Manual of Style (16th Edition):

Zhang, Zhanpeng. “Advanced Microspheres as Injectable Cell Carriers for Tissue Engineering.” 2015. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/111559.

MLA Handbook (7th Edition):

Zhang, Zhanpeng. “Advanced Microspheres as Injectable Cell Carriers for Tissue Engineering.” 2015. Web. 19 Mar 2019.

Vancouver:

Zhang Z. Advanced Microspheres as Injectable Cell Carriers for Tissue Engineering. [Internet] [Doctoral dissertation]. University of Michigan; 2015. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/111559.

Council of Science Editors:

Zhang Z. Advanced Microspheres as Injectable Cell Carriers for Tissue Engineering. [Doctoral Dissertation]. University of Michigan; 2015. Available from: http://hdl.handle.net/2027.42/111559


University of Michigan

9. Wang, Yichun. Three Dimensional Cell Culture: A Window into Transport of Nanomedicine in Tumor Tissue.

Degree: PhD, Biomedical Engineering, 2016, University of Michigan

 Recent growth in nanotechnology has been accelerating the identification and evaluation of new drug candidates. The development, optimization of nanomedicine and preclinical drug screening is… (more)

Subjects/Keywords: 3D cell culture; Nanotechnology; Drug delivery; Cancer treatment; Monte-Carlo simulation; Carbon nanotube; Biomedical Engineering; Engineering

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APA (6th Edition):

Wang, Y. (2016). Three Dimensional Cell Culture: A Window into Transport of Nanomedicine in Tumor Tissue. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/120907

Chicago Manual of Style (16th Edition):

Wang, Yichun. “Three Dimensional Cell Culture: A Window into Transport of Nanomedicine in Tumor Tissue.” 2016. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/120907.

MLA Handbook (7th Edition):

Wang, Yichun. “Three Dimensional Cell Culture: A Window into Transport of Nanomedicine in Tumor Tissue.” 2016. Web. 19 Mar 2019.

Vancouver:

Wang Y. Three Dimensional Cell Culture: A Window into Transport of Nanomedicine in Tumor Tissue. [Internet] [Doctoral dissertation]. University of Michigan; 2016. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/120907.

Council of Science Editors:

Wang Y. Three Dimensional Cell Culture: A Window into Transport of Nanomedicine in Tumor Tissue. [Doctoral Dissertation]. University of Michigan; 2016. Available from: http://hdl.handle.net/2027.42/120907


University of Michigan

10. Misra, Asish C. Multicompartmental Carriers for Medical Applications.

Degree: PhD, Biomedical Engineering, 2016, University of Michigan

 Targeted particulate carrier based therapies have the potential to vastly improve current treatment modalities in medicine by concentrating a therapeutic at its desired target, and… (more)

Subjects/Keywords: multicompartmental particles; carriers for medical applications; targeted drug delivery; targeted therapy; nanoparticles; microparticles; Biomedical Engineering; Engineering

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APA (6th Edition):

Misra, A. C. (2016). Multicompartmental Carriers for Medical Applications. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/120726

Chicago Manual of Style (16th Edition):

Misra, Asish C. “Multicompartmental Carriers for Medical Applications.” 2016. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/120726.

MLA Handbook (7th Edition):

Misra, Asish C. “Multicompartmental Carriers for Medical Applications.” 2016. Web. 19 Mar 2019.

Vancouver:

Misra AC. Multicompartmental Carriers for Medical Applications. [Internet] [Doctoral dissertation]. University of Michigan; 2016. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/120726.

Council of Science Editors:

Misra AC. Multicompartmental Carriers for Medical Applications. [Doctoral Dissertation]. University of Michigan; 2016. Available from: http://hdl.handle.net/2027.42/120726


University of Michigan

11. Aydin, Omer. Development of Novel Nanomedicines for Treatment of Primary and Metastatic Prostate Cancer.

Degree: PhD, Biomedical Engineering, 2016, University of Michigan

 Prostate cancer is the 2nd most common cancer among men worldwide. This thesis addresses current issues of prostate cancer therapy as focusing on development of… (more)

Subjects/Keywords: prostate cancer metastasis; bone metastasis; drug delivery; focal ablation therapy; nanodroplet-mediated histotripsy; nanomedicine; Biomedical Engineering; Engineering

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APA (6th Edition):

Aydin, O. (2016). Development of Novel Nanomedicines for Treatment of Primary and Metastatic Prostate Cancer. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/135816

Chicago Manual of Style (16th Edition):

Aydin, Omer. “Development of Novel Nanomedicines for Treatment of Primary and Metastatic Prostate Cancer.” 2016. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/135816.

MLA Handbook (7th Edition):

Aydin, Omer. “Development of Novel Nanomedicines for Treatment of Primary and Metastatic Prostate Cancer.” 2016. Web. 19 Mar 2019.

Vancouver:

Aydin O. Development of Novel Nanomedicines for Treatment of Primary and Metastatic Prostate Cancer. [Internet] [Doctoral dissertation]. University of Michigan; 2016. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/135816.

Council of Science Editors:

Aydin O. Development of Novel Nanomedicines for Treatment of Primary and Metastatic Prostate Cancer. [Doctoral Dissertation]. University of Michigan; 2016. Available from: http://hdl.handle.net/2027.42/135816


University of Michigan

12. Chang, Rae Sung. PLGA Depots for Controlled Release of Bevacizumab.

Degree: PhD, Pharmaceutical Sciences, 2016, University of Michigan

 The advent of monoclonal antibody (mAb)-based anti-vascular endothelial growth factor (VEGF) therapy for treatment of wet age-related macular degeneration (AMD) has significantly improved the clinical… (more)

Subjects/Keywords: PLGA; Drug delivery; Controlled release; Bevacizumab; Wet AMD; Monoclonal antibody; Biomedical Engineering; Pharmacy and Pharmacology; Engineering; Health Sciences; Science

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APA (6th Edition):

Chang, R. S. (2016). PLGA Depots for Controlled Release of Bevacizumab. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/135820

Chicago Manual of Style (16th Edition):

Chang, Rae Sung. “PLGA Depots for Controlled Release of Bevacizumab.” 2016. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/135820.

MLA Handbook (7th Edition):

Chang, Rae Sung. “PLGA Depots for Controlled Release of Bevacizumab.” 2016. Web. 19 Mar 2019.

Vancouver:

Chang RS. PLGA Depots for Controlled Release of Bevacizumab. [Internet] [Doctoral dissertation]. University of Michigan; 2016. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/135820.

Council of Science Editors:

Chang RS. PLGA Depots for Controlled Release of Bevacizumab. [Doctoral Dissertation]. University of Michigan; 2016. Available from: http://hdl.handle.net/2027.42/135820


University of Michigan

13. Mullen, Douglas Gurnett. Design Challenges in Nanoparticle-based Platforms: Implications for Targeted Drug Delivery Systems.

Degree: PhD, Macromolecular Science & Engineering, 2010, University of Michigan

 Characterization and control of heterogeneous distributions of nanoparticle-ligand components are major design challenges for nanoparticle-based platforms. This dissertation begins with an examination of poly(amidoamine) (PAMAM)… (more)

Subjects/Keywords: Poly(Amidoamine) Dendrimer; Nanotechnology; Drug Delivery; Ligand Distribution; Nanoparticle Design Challenges; Macromolecular Design; Biomedical Engineering; Materials Science and Engineering; Chemistry; Engineering; Health Sciences; Science

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APA (6th Edition):

Mullen, D. G. (2010). Design Challenges in Nanoparticle-based Platforms: Implications for Targeted Drug Delivery Systems. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/77691

Chicago Manual of Style (16th Edition):

Mullen, Douglas Gurnett. “Design Challenges in Nanoparticle-based Platforms: Implications for Targeted Drug Delivery Systems.” 2010. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/77691.

MLA Handbook (7th Edition):

Mullen, Douglas Gurnett. “Design Challenges in Nanoparticle-based Platforms: Implications for Targeted Drug Delivery Systems.” 2010. Web. 19 Mar 2019.

Vancouver:

Mullen DG. Design Challenges in Nanoparticle-based Platforms: Implications for Targeted Drug Delivery Systems. [Internet] [Doctoral dissertation]. University of Michigan; 2010. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/77691.

Council of Science Editors:

Mullen DG. Design Challenges in Nanoparticle-based Platforms: Implications for Targeted Drug Delivery Systems. [Doctoral Dissertation]. University of Michigan; 2010. Available from: http://hdl.handle.net/2027.42/77691

14. Heslinga, Michael J. Fabrication of Spheroidal Microparticles from Biodegradable Polymers for Drug Delivery Application.

Degree: PhD, Chemical Engineering, 2012, University of Michigan

 This work describes the novel fabrication of biodegradable prolate spheroids from poly(lactic-co-glycolic acid) (PLGA) polymers via oil-in-water (O/W) and water-in-oil-in-water (W/O/W) emulsion solvent evaporation methods.… (more)

Subjects/Keywords: Targeted Drug Delivery; PLGA; Spheroid; Microparticle; Chemical Engineering; Engineering

…clot formation [4]. Vascular-targeted drug delivery may provide more effective and… …localized drug delivery of potent therapeutics. Vascular-targeted imaging may help to identify… …white cells during chronic inflammation may be of use for drug delivery. In particular… …growth factor viable targets for drug delivery [29-34]. Targeting the selectins is… …targeted drug delivery may offer better treatment of CAD, utilizing highly potent therapeutics… 

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APA (6th Edition):

Heslinga, M. J. (2012). Fabrication of Spheroidal Microparticles from Biodegradable Polymers for Drug Delivery Application. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/91458

Chicago Manual of Style (16th Edition):

Heslinga, Michael J. “Fabrication of Spheroidal Microparticles from Biodegradable Polymers for Drug Delivery Application.” 2012. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/91458.

MLA Handbook (7th Edition):

Heslinga, Michael J. “Fabrication of Spheroidal Microparticles from Biodegradable Polymers for Drug Delivery Application.” 2012. Web. 19 Mar 2019.

Vancouver:

Heslinga MJ. Fabrication of Spheroidal Microparticles from Biodegradable Polymers for Drug Delivery Application. [Internet] [Doctoral dissertation]. University of Michigan; 2012. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/91458.

Council of Science Editors:

Heslinga MJ. Fabrication of Spheroidal Microparticles from Biodegradable Polymers for Drug Delivery Application. [Doctoral Dissertation]. University of Michigan; 2012. Available from: http://hdl.handle.net/2027.42/91458


University of Michigan

15. Wallace, Rachel. Folate Binding Protein as a Therapeutic Natural Nanotechnology.

Degree: PhD, Chemistry, 2018, University of Michigan

 Serum proteins interact with small molecules and nanoparticles in blood, resulting in protein coronas. Protein coronas influence the bioidentity of the molecules and nanoparticles, playing… (more)

Subjects/Keywords: targeted drug delivery; folate targeted therapy; folate binding protein; folic acid; antifolate therapy; serum proteins; Biological Chemistry; Chemical Engineering; Chemistry; Science (General); Science

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APA (6th Edition):

Wallace, R. (2018). Folate Binding Protein as a Therapeutic Natural Nanotechnology. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/143895

Chicago Manual of Style (16th Edition):

Wallace, Rachel. “Folate Binding Protein as a Therapeutic Natural Nanotechnology.” 2018. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/143895.

MLA Handbook (7th Edition):

Wallace, Rachel. “Folate Binding Protein as a Therapeutic Natural Nanotechnology.” 2018. Web. 19 Mar 2019.

Vancouver:

Wallace R. Folate Binding Protein as a Therapeutic Natural Nanotechnology. [Internet] [Doctoral dissertation]. University of Michigan; 2018. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/143895.

Council of Science Editors:

Wallace R. Folate Binding Protein as a Therapeutic Natural Nanotechnology. [Doctoral Dissertation]. University of Michigan; 2018. Available from: http://hdl.handle.net/2027.42/143895

16. Namdee, Katawut. Exploring the Impact of Hemodynamic and Hemorheology in the Design of Carrier for Vascular-Targeted Drug Delivery in Atherosclerosis.

Degree: PhD, Biomedical Engineering, 2015, University of Michigan

 Recently, vascular targeting drug carriers (VTCs) have become one of the most distinguished aspects in pharmaceutical engineering.In order to sustain the ability of localized drug(more)

Subjects/Keywords: Vascular targeting drug delivery, Microparticles, Nanoparticles, Atherosclerosis; Biomedical Engineering; Engineering

…Hemodynamic and Hemorheology in the Design of Carrier for Vascular-Targeted Drug Delivery in… …important for many research fields, particularly for the design of drug delivery and diagnostics… …diseases via the vascular system. Drug delivery systems enhance drug effectiveness at the… …protein corona For administered drug delivery system, prolonging blood circulation time with low… …S.D. Rodgers, and D.A. Hammer, Characterization of biodegradable drug delivery vehicles with… 

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APA (6th Edition):

Namdee, K. (2015). Exploring the Impact of Hemodynamic and Hemorheology in the Design of Carrier for Vascular-Targeted Drug Delivery in Atherosclerosis. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/111579

Chicago Manual of Style (16th Edition):

Namdee, Katawut. “Exploring the Impact of Hemodynamic and Hemorheology in the Design of Carrier for Vascular-Targeted Drug Delivery in Atherosclerosis.” 2015. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/111579.

MLA Handbook (7th Edition):

Namdee, Katawut. “Exploring the Impact of Hemodynamic and Hemorheology in the Design of Carrier for Vascular-Targeted Drug Delivery in Atherosclerosis.” 2015. Web. 19 Mar 2019.

Vancouver:

Namdee K. Exploring the Impact of Hemodynamic and Hemorheology in the Design of Carrier for Vascular-Targeted Drug Delivery in Atherosclerosis. [Internet] [Doctoral dissertation]. University of Michigan; 2015. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/111579.

Council of Science Editors:

Namdee K. Exploring the Impact of Hemodynamic and Hemorheology in the Design of Carrier for Vascular-Targeted Drug Delivery in Atherosclerosis. [Doctoral Dissertation]. University of Michigan; 2015. Available from: http://hdl.handle.net/2027.42/111579

17. van Dongen-Sohmer, Mallory A. PAMAM Dendrimer as Quantized Building Blocks for Biomedical Applications.

Degree: PhD, Chemistry, 2014, University of Michigan

 Heterogeneity, whether from polydispersity within the polymeric scaffold or due to a broad distribution of covalently conjugated products, is a remaining challenge in theranostics. Chapter… (more)

Subjects/Keywords: PAMAM Dendrimer; Controlled Valency; Targeted Polymer Drug Delivery; Surface Plasmon Resonance; Precise Nanomaterials; Chemistry; Science

drug delivery, and gives some insight to where the field must continue to grow. xxii… …Chapter 1 Multivalent Polymers for Drug Delivery and Imaging Agents: the challenges of… …polymeric scaffold,[11-13] enables multivalent delivery of the drug to the same cell… …to create a multifunctional, targeted, drug delivery vehicle that can be tracked by… …Food and Drug Administration g ......... ...gram G… 

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APA (6th Edition):

van Dongen-Sohmer, M. A. (2014). PAMAM Dendrimer as Quantized Building Blocks for Biomedical Applications. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/107121

Chicago Manual of Style (16th Edition):

van Dongen-Sohmer, Mallory A. “PAMAM Dendrimer as Quantized Building Blocks for Biomedical Applications.” 2014. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/107121.

MLA Handbook (7th Edition):

van Dongen-Sohmer, Mallory A. “PAMAM Dendrimer as Quantized Building Blocks for Biomedical Applications.” 2014. Web. 19 Mar 2019.

Vancouver:

van Dongen-Sohmer MA. PAMAM Dendrimer as Quantized Building Blocks for Biomedical Applications. [Internet] [Doctoral dissertation]. University of Michigan; 2014. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/107121.

Council of Science Editors:

van Dongen-Sohmer MA. PAMAM Dendrimer as Quantized Building Blocks for Biomedical Applications. [Doctoral Dissertation]. University of Michigan; 2014. Available from: http://hdl.handle.net/2027.42/107121

18. Evans, Allan T. Valve Regulated Implantable Intrathecal Drug Deliver for Chronic Pain Management.

Degree: PhD, Electrical Engineering, 2010, University of Michigan

 Chronic pain afflicts an estimated 100 million people in the United States with annual costs exceeding $100 billion. Treatment modalities for severe chronic pain include… (more)

Subjects/Keywords: MEMS; Drug Delivery; Valve; Chronic Pain; Piezoelectric; Volume Efficiency; Electrical Engineering; Engineering

…5 Current drug delivery devices trade functionality and control for size. This work seeks… …Conceptual design of an implantable intrathecal drug delivery device that uses two valves to… …actuation voltages preferred by the drug delivery system design. 83 3-41 Schematic of the… …regulated by a microvalve to control drug delivery rates. Control is regulated by onboard… …A drug delivery prototype pictured during assembly. A polymer reservoir is pressurized… 

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APA (6th Edition):

Evans, A. T. (2010). Valve Regulated Implantable Intrathecal Drug Deliver for Chronic Pain Management. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/75815

Chicago Manual of Style (16th Edition):

Evans, Allan T. “Valve Regulated Implantable Intrathecal Drug Deliver for Chronic Pain Management.” 2010. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/75815.

MLA Handbook (7th Edition):

Evans, Allan T. “Valve Regulated Implantable Intrathecal Drug Deliver for Chronic Pain Management.” 2010. Web. 19 Mar 2019.

Vancouver:

Evans AT. Valve Regulated Implantable Intrathecal Drug Deliver for Chronic Pain Management. [Internet] [Doctoral dissertation]. University of Michigan; 2010. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/75815.

Council of Science Editors:

Evans AT. Valve Regulated Implantable Intrathecal Drug Deliver for Chronic Pain Management. [Doctoral Dissertation]. University of Michigan; 2010. Available from: http://hdl.handle.net/2027.42/75815


University of Michigan

19. Hendricks, Jeffrey L. Bioactive Conducting Polymer Coatings for Implantable Neural and Cochlear Electrodes.

Degree: PhD, Biomedical Engineering, 2008, University of Michigan

 Neural prostheses facilitate communication with the nervous system for the diagnosis, treatment, and recovery from neurological illness or trauma. These devices require permanently implanted electrodes… (more)

Subjects/Keywords: Neural Prostheses; Cochlear Implants; Conducting Polymers; Electrodes; Cell and Drug Delivery; Biomedical Engineering; Engineering

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APA (6th Edition):

Hendricks, J. L. (2008). Bioactive Conducting Polymer Coatings for Implantable Neural and Cochlear Electrodes. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/61684

Chicago Manual of Style (16th Edition):

Hendricks, Jeffrey L. “Bioactive Conducting Polymer Coatings for Implantable Neural and Cochlear Electrodes.” 2008. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/61684.

MLA Handbook (7th Edition):

Hendricks, Jeffrey L. “Bioactive Conducting Polymer Coatings for Implantable Neural and Cochlear Electrodes.” 2008. Web. 19 Mar 2019.

Vancouver:

Hendricks JL. Bioactive Conducting Polymer Coatings for Implantable Neural and Cochlear Electrodes. [Internet] [Doctoral dissertation]. University of Michigan; 2008. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/61684.

Council of Science Editors:

Hendricks JL. Bioactive Conducting Polymer Coatings for Implantable Neural and Cochlear Electrodes. [Doctoral Dissertation]. University of Michigan; 2008. Available from: http://hdl.handle.net/2027.42/61684

20. Ross, Astin Marie. Characterization of Multicompartmental Microparticles for Cochlear Drug Delivery.

Degree: PhD, Biomedical Engineering, 2014, University of Michigan

 Cochlear implants (CIs) are the preferred treatment for patients with moderate to profound sensorineural hearing loss. However, increasing numbers of CI recipients have remaining hearing… (more)

Subjects/Keywords: Drug Delivery; Biomaterials; Microparticle; Electrohydrodynamic Co-jetting; Cochlea; Biomedical Engineering; Otolaryngology; Engineering; Health Sciences

…xv Chapter 1 Introduction: Cochlear Trauma and Drug Delivery… …6 1.5. Challenges of Drug Delivery to the Cochlea… …9 1.6. Drug Delivery (Systemic vs. Local)… …10 1.7. Particles as a Means of Facilitating Drug Delivery to the Cochlea… …18 Chapter 2 Cochlear Drug Delivery Process Design Parameter Determination… 

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APA (6th Edition):

Ross, A. M. (2014). Characterization of Multicompartmental Microparticles for Cochlear Drug Delivery. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/107313

Chicago Manual of Style (16th Edition):

Ross, Astin Marie. “Characterization of Multicompartmental Microparticles for Cochlear Drug Delivery.” 2014. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/107313.

MLA Handbook (7th Edition):

Ross, Astin Marie. “Characterization of Multicompartmental Microparticles for Cochlear Drug Delivery.” 2014. Web. 19 Mar 2019.

Vancouver:

Ross AM. Characterization of Multicompartmental Microparticles for Cochlear Drug Delivery. [Internet] [Doctoral dissertation]. University of Michigan; 2014. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/107313.

Council of Science Editors:

Ross AM. Characterization of Multicompartmental Microparticles for Cochlear Drug Delivery. [Doctoral Dissertation]. University of Michigan; 2014. Available from: http://hdl.handle.net/2027.42/107313

21. Qin, Ming. Development of Targeted Hydrogel Nanoparticles as Delivery Vehicles for Cancer Therapy and Imaging.

Degree: PhD, Chemistry, 2014, University of Michigan

 Nanotechnology can provide powerful delivery carriers for cancer therapy. This dissertation addressed some key challenges for the development of nano-drug carriers: targeted therapy, multidrug resistance… (more)

Subjects/Keywords: Hydrogel Nanoparticle; Drug Delivery; Photodynamic Therapy; Methylene Blue; Doxorubicin; Multidrug Resistance; Chemistry; Science

…Baban, D.F. and L.W. Seymour, Control of tumour vascular permeability. Advanced Drug Delivery… …G.Y. Bharate, and J. Daruwalla, Polymeric drugs for efficient tumor-targeted drug delivery… …and Treatment of Cancer: Multifunctional Nanoparticles for Drug Delivery Applications, S… …Cullis, Drug Delivery Systems: Entering the Mainstream. Science, 2004. 303(5665): p… …Dubernet, and P. Couvreur, Nanoparticles in cancer therapy and diagnosis. Advanced Drug Delivery… 

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APA (6th Edition):

Qin, M. (2014). Development of Targeted Hydrogel Nanoparticles as Delivery Vehicles for Cancer Therapy and Imaging. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/107196

Chicago Manual of Style (16th Edition):

Qin, Ming. “Development of Targeted Hydrogel Nanoparticles as Delivery Vehicles for Cancer Therapy and Imaging.” 2014. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/107196.

MLA Handbook (7th Edition):

Qin, Ming. “Development of Targeted Hydrogel Nanoparticles as Delivery Vehicles for Cancer Therapy and Imaging.” 2014. Web. 19 Mar 2019.

Vancouver:

Qin M. Development of Targeted Hydrogel Nanoparticles as Delivery Vehicles for Cancer Therapy and Imaging. [Internet] [Doctoral dissertation]. University of Michigan; 2014. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/107196.

Council of Science Editors:

Qin M. Development of Targeted Hydrogel Nanoparticles as Delivery Vehicles for Cancer Therapy and Imaging. [Doctoral Dissertation]. University of Michigan; 2014. Available from: http://hdl.handle.net/2027.42/107196

22. Fan, Zhenzhen. Study of the Mechanisms of Microbubble-Facilitated Sonoporation in vitro in Controlled Environments.

Degree: PhD, Biomedical Engineering, 2012, University of Michigan

 Successful delivery of drug molecules and therapeutic genetic materials across the plasma membrane into the target cells in sufficient dosage is important for satisfactory treatment… (more)

Subjects/Keywords: Sonoporation; Microbubble; Ultrasound; Intracellular Drug and Gene Delivery; Calcium Imaging; Biomedical Engineering; Engineering

…99 xiii Abstract Successful delivery of drug molecules and therapeutic genetic materials… …intracellular drug and gene delivery. When excited by ultrasound, microbubbles undergo rapid volume… …delivery of drug molecules and therapeutic genetic materials across the plasma membrane into the… …exploited as a new strategy for non-viral intracellular drug and gene delivery [3-10]… …to achieve controlled and improved drug and gene delivery outcomes. Designed to address the… 

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APA (6th Edition):

Fan, Z. (2012). Study of the Mechanisms of Microbubble-Facilitated Sonoporation in vitro in Controlled Environments. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/91472

Chicago Manual of Style (16th Edition):

Fan, Zhenzhen. “Study of the Mechanisms of Microbubble-Facilitated Sonoporation in vitro in Controlled Environments.” 2012. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/91472.

MLA Handbook (7th Edition):

Fan, Zhenzhen. “Study of the Mechanisms of Microbubble-Facilitated Sonoporation in vitro in Controlled Environments.” 2012. Web. 19 Mar 2019.

Vancouver:

Fan Z. Study of the Mechanisms of Microbubble-Facilitated Sonoporation in vitro in Controlled Environments. [Internet] [Doctoral dissertation]. University of Michigan; 2012. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/91472.

Council of Science Editors:

Fan Z. Study of the Mechanisms of Microbubble-Facilitated Sonoporation in vitro in Controlled Environments. [Doctoral Dissertation]. University of Michigan; 2012. Available from: http://hdl.handle.net/2027.42/91472

23. Medina, Scott H. Development of Targeted, Enzyme-Activated, Dendrimer-Drug Nano-Conjugates for Hepatic Cancer Therapy.

Degree: PhD, Biomedical Engineering, 2012, University of Michigan

 Primary liver cancer is the 4th most common malignancy worldwide, accounting for >600,000 deaths/year globally. Loco-regional chemotherapy fails to deliver anticancer drugs specifically to hepatic… (more)

Subjects/Keywords: Drug Delivery; PAMAM Dendrimers; Liver Cancer; Hepatocellular Carcinoma; Hepatic Cancer Cell Targeting; Azoreductase; Biomedical Engineering; Engineering

…showing the diffusion of drug delivery systems across the leaky vasculature into the tumor mass… …targeting and drug delivery to hepatic cancer cells in vitro and in vivo.22 Li et al. developed… …liposome drug delivery systems. J. Pharm. Sci. 90, 667-680 (2001). Papagiannaros, A… …Kataoka, K., Harada, A. & Nagasaki, Y. Block copolymer micelles for drug delivery: design… …Cleavable Linkers for Hepatic Cancer Cell-Specific Drug Release ..… 6.1.2 Impact of… 

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APA (6th Edition):

Medina, S. H. (2012). Development of Targeted, Enzyme-Activated, Dendrimer-Drug Nano-Conjugates for Hepatic Cancer Therapy. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/93863

Chicago Manual of Style (16th Edition):

Medina, Scott H. “Development of Targeted, Enzyme-Activated, Dendrimer-Drug Nano-Conjugates for Hepatic Cancer Therapy.” 2012. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/93863.

MLA Handbook (7th Edition):

Medina, Scott H. “Development of Targeted, Enzyme-Activated, Dendrimer-Drug Nano-Conjugates for Hepatic Cancer Therapy.” 2012. Web. 19 Mar 2019.

Vancouver:

Medina SH. Development of Targeted, Enzyme-Activated, Dendrimer-Drug Nano-Conjugates for Hepatic Cancer Therapy. [Internet] [Doctoral dissertation]. University of Michigan; 2012. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/93863.

Council of Science Editors:

Medina SH. Development of Targeted, Enzyme-Activated, Dendrimer-Drug Nano-Conjugates for Hepatic Cancer Therapy. [Doctoral Dissertation]. University of Michigan; 2012. Available from: http://hdl.handle.net/2027.42/93863

24. Fabiilli, Mario Leonardo. Ultrasound-triggered Drug Delivery Using Acoustic Droplet Vaporization.

Degree: PhD, Biomedical Engineering, 2010, University of Michigan

 The goal of targeted drug delivery is the spatial and temporal localization of a therapeutic agent and its associated bioeffects. One method of drug localization… (more)

Subjects/Keywords: Acoustic Droplet Vaporization; Emulsion; Drug Delivery; Ultrasound; Perfluorocarbon; Cavitation; Biomedical Engineering; Radiology; Physics; Engineering; Health Sciences; Science

…Targeted Drug Delivery . . . . . . . . . . . . 1.2.1 Pharmaceutical Approaches… …Published drug delivery studies using ADV . . . . . . . . . . . . . . 2.1 Boiling points (… …DRUG DELIVERY USING ACOUSTIC DROPLET VAPORIZATION by Mario Leonardo Fabiilli Chair: J. Brian… …Fowlkes The goal of targeted drug delivery is the spatial and temporal localization of a… …inertial cavitation (IC) thresholds - relevant for drug delivery due to the bioffects… 

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APA (6th Edition):

Fabiilli, M. L. (2010). Ultrasound-triggered Drug Delivery Using Acoustic Droplet Vaporization. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/78925

Chicago Manual of Style (16th Edition):

Fabiilli, Mario Leonardo. “Ultrasound-triggered Drug Delivery Using Acoustic Droplet Vaporization.” 2010. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/78925.

MLA Handbook (7th Edition):

Fabiilli, Mario Leonardo. “Ultrasound-triggered Drug Delivery Using Acoustic Droplet Vaporization.” 2010. Web. 19 Mar 2019.

Vancouver:

Fabiilli ML. Ultrasound-triggered Drug Delivery Using Acoustic Droplet Vaporization. [Internet] [Doctoral dissertation]. University of Michigan; 2010. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/78925.

Council of Science Editors:

Fabiilli ML. Ultrasound-triggered Drug Delivery Using Acoustic Droplet Vaporization. [Doctoral Dissertation]. University of Michigan; 2010. Available from: http://hdl.handle.net/2027.42/78925

25. Zheng, Nan. Cheminformatic and Mechanistic Study of Drug Subcellular Transport/Distribution.

Degree: PhD, Pharmaceutical Sciences, 2011, University of Michigan

 The subcellular transport and distribution behavior determines both the pharmacological effect on the cellular level and the drug exposure at a tissue, organ and whole… (more)

Subjects/Keywords: Pharmacokinetics; Subcellular Transport; Organelle-targeting; Drug Delivery; Modeling and Simulation; Pharmacy and Pharmacology; Science (General); Health Sciences; Science

drug delivery. 2 Introduction Despite of the rapid development in combinatorial chemistry… …serve as a stepping stone towards developing new drug delivery strategies and therapeutic… …Drug-likeness based on Lipinski’s Rule of Five and lead-likeness based on Oprea’s Rules of… …molecules with drug properties . 312 Appendix J. Chemical structures of the random… …sample from PubChem database representing small organic compounds without drug related… 

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APA (6th Edition):

Zheng, N. (2011). Cheminformatic and Mechanistic Study of Drug Subcellular Transport/Distribution. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/89626

Chicago Manual of Style (16th Edition):

Zheng, Nan. “Cheminformatic and Mechanistic Study of Drug Subcellular Transport/Distribution.” 2011. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/89626.

MLA Handbook (7th Edition):

Zheng, Nan. “Cheminformatic and Mechanistic Study of Drug Subcellular Transport/Distribution.” 2011. Web. 19 Mar 2019.

Vancouver:

Zheng N. Cheminformatic and Mechanistic Study of Drug Subcellular Transport/Distribution. [Internet] [Doctoral dissertation]. University of Michigan; 2011. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/89626.

Council of Science Editors:

Zheng N. Cheminformatic and Mechanistic Study of Drug Subcellular Transport/Distribution. [Doctoral Dissertation]. University of Michigan; 2011. Available from: http://hdl.handle.net/2027.42/89626

26. Gibson, Matthew Donivan. Neural Biosensor Probes for Simultaneous Electrophysiological Recordings, Neurochemical Measurements, and Drug Delivery with High Spatial and Temporal Resolution.

Degree: PhD, Biomedical Engineering, 2011, University of Michigan

 The aim of this work is to develop and validate novel neural biosensor probes for simultaneous electrophysiological and neurochemical measurements with precise, localized drug delivery.… (more)

Subjects/Keywords: Multimodal Neural Biosensor Probe; Neurotransmitters Choline Glutamate; Electrophysiology; Drug Delivery; In Vivo Voltammetry Amperometry; Neurochemical Sensing; Biomedical Engineering; Engineering

…Recordings with Localized Drug Delivery 3.1 3.2 Introduction… …Electrophysiology, Cholinergic Recording, and Drug Delivery… …Measurements, and Drug Delivery with High Spatial and Temporal Resolution by Matthew Donivan Gibson… …localized drug delivery. This technology has been developed to interface with the complex… …detection of choline, recording of electrophysiology, and localized drug delivery. Central to this… 

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APA (6th Edition):

Gibson, M. D. (2011). Neural Biosensor Probes for Simultaneous Electrophysiological Recordings, Neurochemical Measurements, and Drug Delivery with High Spatial and Temporal Resolution. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/89722

Chicago Manual of Style (16th Edition):

Gibson, Matthew Donivan. “Neural Biosensor Probes for Simultaneous Electrophysiological Recordings, Neurochemical Measurements, and Drug Delivery with High Spatial and Temporal Resolution.” 2011. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/89722.

MLA Handbook (7th Edition):

Gibson, Matthew Donivan. “Neural Biosensor Probes for Simultaneous Electrophysiological Recordings, Neurochemical Measurements, and Drug Delivery with High Spatial and Temporal Resolution.” 2011. Web. 19 Mar 2019.

Vancouver:

Gibson MD. Neural Biosensor Probes for Simultaneous Electrophysiological Recordings, Neurochemical Measurements, and Drug Delivery with High Spatial and Temporal Resolution. [Internet] [Doctoral dissertation]. University of Michigan; 2011. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/89722.

Council of Science Editors:

Gibson MD. Neural Biosensor Probes for Simultaneous Electrophysiological Recordings, Neurochemical Measurements, and Drug Delivery with High Spatial and Temporal Resolution. [Doctoral Dissertation]. University of Michigan; 2011. Available from: http://hdl.handle.net/2027.42/89722

27. Mazzara, John Maxwell. Self-Encapsulation of Vaccine Antigens in PLGA Microparticles and Microneedles.

Degree: PhD, Pharmaceutical Sciences, 2016, University of Michigan

 There is an urgent need to reduce reliance on hypodermic injections for many protein-based therapies. Alternative approaches include developing controlled release formulations, which reduce dosing… (more)

Subjects/Keywords: Controlled Release; Drug Delivery; Vaccines; Microneedles; Pharmaceutical Sciences; Microparticles; Pharmacy and Pharmacology; Science (General); Health Sciences; Science

…release drug delivery (CRDD) systems that are designed to maintain therapeutic… …irreversible protein aggregation (9, 10). Furthermore, for use in humans, drug delivery… …which reduce dosing frequencies, and utilizing alternative delivery devices, such as… …benefits, and above it the drug may begin to demonstrate deleterious side effects. In order to… …maintain drug concentrations within this therapeutic window, many therapies are given on a… 

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APA (6th Edition):

Mazzara, J. M. (2016). Self-Encapsulation of Vaccine Antigens in PLGA Microparticles and Microneedles. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/133322

Chicago Manual of Style (16th Edition):

Mazzara, John Maxwell. “Self-Encapsulation of Vaccine Antigens in PLGA Microparticles and Microneedles.” 2016. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/133322.

MLA Handbook (7th Edition):

Mazzara, John Maxwell. “Self-Encapsulation of Vaccine Antigens in PLGA Microparticles and Microneedles.” 2016. Web. 19 Mar 2019.

Vancouver:

Mazzara JM. Self-Encapsulation of Vaccine Antigens in PLGA Microparticles and Microneedles. [Internet] [Doctoral dissertation]. University of Michigan; 2016. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/133322.

Council of Science Editors:

Mazzara JM. Self-Encapsulation of Vaccine Antigens in PLGA Microparticles and Microneedles. [Doctoral Dissertation]. University of Michigan; 2016. Available from: http://hdl.handle.net/2027.42/133322

28. Sobczynski, Daniel J. The Impact of the Plasma Protein Corona on the Adhesion Efficiency of Drug Carriers to the Blood Vessel Wall.

Degree: PhD, Chemical Engineering, 2016, University of Michigan

 Upon injection of vascular-targeted drug carriers into the bloodstream, plasma proteins rapidly coat the carrier surface, forming a plasma protein corona. This corona is dependent… (more)

Subjects/Keywords: Plasma protein corona; Vascular-targeted drug delivery; Blood flow adhesion efficiency; Biomedical Engineering; Chemical Engineering; Engineering; Science

…presence of corona formation. Second, this work may explain why current targeted drug delivery… …leading to more successful translations of drug delivery systems to the market. Overall, this… …protein in drug delivery is reviewed as well as important parameters which affect the corona… …effects over systemic drug delivery. This “targeted” delivery approach has been rigorously… …targeted therapies designed to achieve localized delivery, facilitated via particulate drug… 

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APA (6th Edition):

Sobczynski, D. J. (2016). The Impact of the Plasma Protein Corona on the Adhesion Efficiency of Drug Carriers to the Blood Vessel Wall. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/133204

Chicago Manual of Style (16th Edition):

Sobczynski, Daniel J. “The Impact of the Plasma Protein Corona on the Adhesion Efficiency of Drug Carriers to the Blood Vessel Wall.” 2016. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/133204.

MLA Handbook (7th Edition):

Sobczynski, Daniel J. “The Impact of the Plasma Protein Corona on the Adhesion Efficiency of Drug Carriers to the Blood Vessel Wall.” 2016. Web. 19 Mar 2019.

Vancouver:

Sobczynski DJ. The Impact of the Plasma Protein Corona on the Adhesion Efficiency of Drug Carriers to the Blood Vessel Wall. [Internet] [Doctoral dissertation]. University of Michigan; 2016. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/133204.

Council of Science Editors:

Sobczynski DJ. The Impact of the Plasma Protein Corona on the Adhesion Efficiency of Drug Carriers to the Blood Vessel Wall. [Doctoral Dissertation]. University of Michigan; 2016. Available from: http://hdl.handle.net/2027.42/133204

29. Cline, Erika N. Interactions Between Nanoparticles and Biological Charged Lines: Biological Mimics of Protein-DNA Complexes and Microtubules as Drug Targets.

Degree: PhD, Cellular & Molecular Biology, 2013, University of Michigan

 DNA-binding proteins use a combination of the following mechanisms to find their DNA target sites: “hopping” or “jumping” along DNA (3D diffusion), intersegment transfer, sliding… (more)

Subjects/Keywords: Nanotechnology; Targeted Drug Delivery; Nanoparticle Toxicity; Microtubules; Paclitaxel; Biosensing and Bioactuation; Molecular, Cellular and Developmental Biology; Science

…microtubules with paclitaxel may also be of interest as a potential targeted drug delivery strategy… …decreased drug efficiency. 30 Accordingly, numerous targeted delivery strategies for paclitaxel… …nanoparticles as a targeted cancer drug delivery strategy. One finding from this investigation was… …conjugated gold nanoparticles as a targeted cancer drug delivery platform; and (2) an… …Charged Lines: Biological Mimics of Protein-DNA Complexes and Microtubules as Drug Targets by… 

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APA (6th Edition):

Cline, E. N. (2013). Interactions Between Nanoparticles and Biological Charged Lines: Biological Mimics of Protein-DNA Complexes and Microtubules as Drug Targets. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/99762

Chicago Manual of Style (16th Edition):

Cline, Erika N. “Interactions Between Nanoparticles and Biological Charged Lines: Biological Mimics of Protein-DNA Complexes and Microtubules as Drug Targets.” 2013. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/99762.

MLA Handbook (7th Edition):

Cline, Erika N. “Interactions Between Nanoparticles and Biological Charged Lines: Biological Mimics of Protein-DNA Complexes and Microtubules as Drug Targets.” 2013. Web. 19 Mar 2019.

Vancouver:

Cline EN. Interactions Between Nanoparticles and Biological Charged Lines: Biological Mimics of Protein-DNA Complexes and Microtubules as Drug Targets. [Internet] [Doctoral dissertation]. University of Michigan; 2013. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/99762.

Council of Science Editors:

Cline EN. Interactions Between Nanoparticles and Biological Charged Lines: Biological Mimics of Protein-DNA Complexes and Microtubules as Drug Targets. [Doctoral Dissertation]. University of Michigan; 2013. Available from: http://hdl.handle.net/2027.42/99762

30. Adeniyi, Oluseyi Abiola. Characterization of Flagellin-Functionalized Liposomes as a Vaccine Carrier and Adjuvant.

Degree: PhD, Pharmaceutical Sciences, 2015, University of Michigan

 Since the recognition that the adjuvant capacity of flagellin is better harnessed when both flagellin and the antigen are delivered to the same cell, there… (more)

Subjects/Keywords: TLR5; Vaccine delivery; Liposomes; Drug targeting; Flagellin; Adjuvant; Biomedical Engineering; Pharmacy and Pharmacology; Science (General); Health Sciences; Science

…112 APPENDIX Histone H2A enhances the capability of LLO LPDII as a nuclear delivery vector… …115 The potential and use of histone proteins for DNA condensation and nuclear delivery… …118 Utilizing listeriolysin O (LLO) to enhance DNA vaccination and gene delivery… …delivery in vitro… …constraint. We propose a liposomal delivery system functionalized with Salmonella typhimurium… 

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Adeniyi, O. A. (2015). Characterization of Flagellin-Functionalized Liposomes as a Vaccine Carrier and Adjuvant. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/113296

Chicago Manual of Style (16th Edition):

Adeniyi, Oluseyi Abiola. “Characterization of Flagellin-Functionalized Liposomes as a Vaccine Carrier and Adjuvant.” 2015. Doctoral Dissertation, University of Michigan. Accessed March 19, 2019. http://hdl.handle.net/2027.42/113296.

MLA Handbook (7th Edition):

Adeniyi, Oluseyi Abiola. “Characterization of Flagellin-Functionalized Liposomes as a Vaccine Carrier and Adjuvant.” 2015. Web. 19 Mar 2019.

Vancouver:

Adeniyi OA. Characterization of Flagellin-Functionalized Liposomes as a Vaccine Carrier and Adjuvant. [Internet] [Doctoral dissertation]. University of Michigan; 2015. [cited 2019 Mar 19]. Available from: http://hdl.handle.net/2027.42/113296.

Council of Science Editors:

Adeniyi OA. Characterization of Flagellin-Functionalized Liposomes as a Vaccine Carrier and Adjuvant. [Doctoral Dissertation]. University of Michigan; 2015. Available from: http://hdl.handle.net/2027.42/113296

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