subject:(Dosage)

1. Soruco, Marcela. The CLAMP protein is essential in Drosophila in mediating dosage compensation through increased targeting to the X-chromosome and during development as a non-sex specific transcription factor.

Degree: PhD, Molecular Biology, Cell Biology, and Biochemistry, 2014, Brown University

URL: https://repository.library.brown.edu/studio/item/bdr:386283/

► Dosage compensation in Drosophila is a valuable model for studying how transcription complexes are targeted throughout the genome because all of the genes along the… (more)

▼ Dosage compensation in Drosophila is a valuable model for studying how transcription complexes are targeted throughout the genome because all of the genes along the length of a single chromosome are identified for co-regulation. In Drosophila, dosage compensation is mediated by the Male Specific Lethal (MSL) complex, which increases transcript levels of X-linked genes in males approximately two-fold to equalize expression levels with the two X chromosomes in females as well as with autosomes. It is thought that the MSL complex identifies the X chromosome in multiple steps. First, the roX loci are though to be targeted which encode the two non-coding RNA components of complex. Next, in a sequence dependent step, a series of high affinity sites containing cis-acting GA-rich MSL Recognition Elements (MRE) are targeted. Finally, sequence-independent spreading of the MSL complex occurs along the X chromosome through the recognition of specific histone modifications association with active transcription. Recently, we identified a previously unstudied zinc finger protein, Chromatin-linked adaptor for MSL proteins (CLAMP), as a key regulator of Drosophila dosage compensation. CLAMP is able to directly target MRE sequences and is enriched at MSL high affinity sites on the X chromosome including the roX loci. Enrichment of CLAMP at the roX loci could identify them as “seed sites” for MSL recruitment that initiates the X-identification cascade. CLAMP is found at the promoters of many active genes in male and female cells, is an essential protein in both males and females and is therefore not a sex-specific factor. To investigate CLAMP as a genome wide transcription factor, we analyzed a fly line containing a P-element insertion and performed mRNA-seq in male and female cells. Using the P-element insertion fly line, we uncovered a new role for CLAMP in development where decreased CLAMP levels caused sever viability and motor defects in male and females with males being very sensitive to the loss of CLAMP. Using mRNA-seq, we found CLAMP regulating genes involved in neuromuscular development. Understanding how the non-sex specific function and the dosage compensation function of CLAMP is integrated is critical in understanding how dosage compensation evolved in Drosophila Advisors/Committee Members: Erica, Larschan (Director), Mark, Johnson (Reader), Robert, Reenan (Reader), Nicola, Neretti (Reader), Fred, Winston (Reader).

Subjects/Keywords: dosage compensation

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APA (6^th Edition):

Soruco, M. (2014). The CLAMP protein is essential in Drosophila in mediating dosage compensation through increased targeting to the X-chromosome and during development as a non-sex specific transcription factor. (Doctoral Dissertation). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:386283/

Chicago Manual of Style (16^th Edition):

Soruco, Marcela. “The CLAMP protein is essential in Drosophila in mediating dosage compensation through increased targeting to the X-chromosome and during development as a non-sex specific transcription factor.” 2014. Doctoral Dissertation, Brown University. Accessed February 17, 2020. https://repository.library.brown.edu/studio/item/bdr:386283/.

MLA Handbook (7^th Edition):

Soruco, Marcela. “The CLAMP protein is essential in Drosophila in mediating dosage compensation through increased targeting to the X-chromosome and during development as a non-sex specific transcription factor.” 2014. Web. 17 Feb 2020.

Vancouver:

Soruco M. The CLAMP protein is essential in Drosophila in mediating dosage compensation through increased targeting to the X-chromosome and during development as a non-sex specific transcription factor. [Internet] [Doctoral dissertation]. Brown University; 2014. [cited 2020 Feb 17]. Available from: https://repository.library.brown.edu/studio/item/bdr:386283/.

Council of Science Editors:

Soruco M. The CLAMP protein is essential in Drosophila in mediating dosage compensation through increased targeting to the X-chromosome and during development as a non-sex specific transcription factor. [Doctoral Dissertation]. Brown University; 2014. Available from: https://repository.library.brown.edu/studio/item/bdr:386283/

University of Missouri – Columbia

2. Sun, Lin. Studies on the mechanisms of action of the male specific lethal complex in Drosophila.

Degree: 2011, University of Missouri – Columbia

URL: http://hdl.handle.net/10355/15845

► [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Dosage compensation is achieved by a twofold up-regulation of the single X chromosome in… (more)

▼ [ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Dosage compensation is achieved by a twofold up-regulation of the single X chromosome in male Drosophila. The inverse dosage effect produced by the single dose of the X chromosome increases the expression of the X chromosome and autosomes. In order to equalize the autosomal expression in males and females, the MSL complex, formed by the active MSL2 protein in males, is sequestered from the autosomes to the X chromosome, including the histone acetylase MOF, to nullify the overexpression of autosomal genes but allows this effect to act on the X chromosome. The X linked genes in males are up-regulated twofold to reach the level of two X chromosomes in females. To investigate the repressive property of the MSL complex, selected protein components of the complex were combined with the yeast GAL4 binding domain. When targeted to a UAS-minimal promoter mini-white reporter, which was recovered at several X and autosomal positions, GAL4-MOF causes up-regulation in females but down-regulation in males. By using immuno-staining and FISH, it was found that the whole MSL complex is recruited to the sites of the reporter genes in males and conditions an increased level of histone acetylation, but in females only the high acetylation co-localized with the reporter, which was further confirmed by ChIP (Chromatin Immunoprecipitation). Using a GAL4-MSL2 construct does not cause dosage compensation on X and autosomal reporters in females, although the ectopically expressed MSL causes the organization of the MSL complex on the reporter genes with an increased histone acetylation. When the ectopically expressing MSL2 without GAL4 DNA binding domain in GAL4-MOF targeted systems, we found that the increased expression in females and the reduced expression in males, caused by the MOF fusion protein, have been reversed. Global gene expression on both the X chromosome and autosomes are increased in mle/mle mutant males, in which the MSL complex is destroyed. This result is consistent with the expression analyses of the X-linked and autosomal reporter genes in the mle/mle mutant background. The high level of histone acetylation on the autosomes, produced by the release of histone modifier, MOF, induces the elevated expression and the inverse dosage effect is allowed to operate on the X chromosome to maintain dosage compensation. All these data indicate that the MSL complex does not condition dosage compensation directly, but rather its repressive activity overrides the high level of histone acetylation and counteracts the over-expression of X-linked genes to achieve the proper two-fold up-regulation in males. Advisors/Committee Members: Birchler, James A. (James Arthur), 1950- (advisor).

Subjects/Keywords: inverse dosage effect; dosage compensation; autosomal expression

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APA (6^th Edition):

Sun, L. (2011). Studies on the mechanisms of action of the male specific lethal complex in Drosophila. (Thesis). University of Missouri – Columbia. Retrieved from http://hdl.handle.net/10355/15845

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sun, Lin. “Studies on the mechanisms of action of the male specific lethal complex in Drosophila.” 2011. Thesis, University of Missouri – Columbia. Accessed February 17, 2020. http://hdl.handle.net/10355/15845.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sun, Lin. “Studies on the mechanisms of action of the male specific lethal complex in Drosophila.” 2011. Web. 17 Feb 2020.

Vancouver:

Sun L. Studies on the mechanisms of action of the male specific lethal complex in Drosophila. [Internet] [Thesis]. University of Missouri – Columbia; 2011. [cited 2020 Feb 17]. Available from: http://hdl.handle.net/10355/15845.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sun L. Studies on the mechanisms of action of the male specific lethal complex in Drosophila. [Thesis]. University of Missouri – Columbia; 2011. Available from: http://hdl.handle.net/10355/15845

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

NSYSU

3. Lin, Yi-Heng. The optimal treatment method of water turbidity purification in tap-water plant.

Degree: Master, Applied Mathematics, 2010, NSYSU

URL: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0728110-161521

► The main purpose of this study is to investigate the relationship between the water turbidity purification result with raw water turbidity, raw water pH value… (more)

Subjects/Keywords: optimization; dosage; regression

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APA (6^th Edition):

Lin, Y. (2010). The optimal treatment method of water turbidity purification in tap-water plant. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0728110-161521

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Lin, Yi-Heng. “The optimal treatment method of water turbidity purification in tap-water plant.” 2010. Thesis, NSYSU. Accessed February 17, 2020. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0728110-161521.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Lin, Yi-Heng. “The optimal treatment method of water turbidity purification in tap-water plant.” 2010. Web. 17 Feb 2020.

Vancouver:

Lin Y. The optimal treatment method of water turbidity purification in tap-water plant. [Internet] [Thesis]. NSYSU; 2010. [cited 2020 Feb 17]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0728110-161521.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Lin Y. The optimal treatment method of water turbidity purification in tap-water plant. [Thesis]. NSYSU; 2010. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0728110-161521

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

4. Schneider, Anna-Maria. Personalized asthma medication.

Degree: Umeå Institute of Design, 2015, Umeå University

URL: http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-125892

► The aim of my master degree project of Advanced Product Design was to develop a monitoring and medication device to empower people who are… (more)

Subjects/Keywords: asthma; medicine; dosage

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APA (6^th Edition):

Schneider, A. (2015). Personalized asthma medication. (Thesis). Umeå University. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-125892

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Schneider, Anna-Maria. “Personalized asthma medication.” 2015. Thesis, Umeå University. Accessed February 17, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-125892.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Schneider, Anna-Maria. “Personalized asthma medication.” 2015. Web. 17 Feb 2020.

Vancouver:

Schneider A. Personalized asthma medication. [Internet] [Thesis]. Umeå University; 2015. [cited 2020 Feb 17]. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-125892.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Schneider A. Personalized asthma medication. [Thesis]. Umeå University; 2015. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-125892

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Malmö University

5. Al-Okshi, Ayman. Maxillofacial cone beam computed tomography (CBCT) : aspetcs on optimisation .

Degree: Malmö University. Faculty of Odontology, 2017, Malmö University

URL: http://hdl.handle.net/2043/23279

► Maxillofacial Cone Beam Computed Tomography (CBCT) has become a common modality for imaging of the facial skeleton. The increased, and sometimes inappropriate, use of this… (more)

▼ Maxillofacial Cone Beam Computed Tomography (CBCT) has become a common modality for imaging of the facial skeleton. The increased, and sometimes inappropriate, use of this modality and the fact that radi-ation doses from CBCT examinations are generally higher than those from conventional radiography will result in an increase in the radiation dose and radiation-associated risk to which patients are exposed. There-fore, the radiation protection principles, justification and optimisation of protection, recommended by the International Commission on Radiological Protection (ICRP) should be applied. Justification of clinical indication is the most important aspect of reducing radiation dose with CBCT scanning. In terms of optimisation, the examination should be performed exposing the patient to the lowest possible radiation dose whilst simultaneously obtaining the image quality required for the diagnostic task. The overall objective of this thesis was to clarify some aspects of optimisation for CBCT examinations. STUDY I comprised a systematic review with the aim to estimate effec-tive dose of CBCT of the facial skeleton with focus on measurement methods and scanning protocols that were used when measuring and es-timating the radiation dosage and effective doses range. The review ad-hered to the preferred reporting items for systematic reviews (PRISMA) statement. Three electronic databases were searched and 38 studies ultimately met the inclusion criteria. Heterogeneity in measurement methods and scanning protocols between studies made comparisons of effective doses of different CBCT units and scanning protocols difficult. A model with minimum data set on important parameters based on this observation of heterogeneity was proposed. Few studies related ef-fective dose to image quality and consequently the review revealed a need for studies on radiation dosages related to image quality. STUDY II demonstrated the feasibility of GafChromic® film XR-QA2 (ISP Corp., Wayne, NJ) as a dosimeter when performing measurements of the effective dose from three different CBCT units and comparing doses from 3 common dental clinical situations. The CBCT units used were Veraviewepocs 3De® (J Morita MFG Corp., Kyoto, Japan), Pro-Max® 3D (Planmeca, Helsinki, Finland) and NewTom VGi® (Quantita-tive Radiology, Verona, Italy). Depending on availability, medium and smaller field of view (FOV) scanning modes were used. Additionally, radiation doses from the three CBCT units were compared with radia-tion doses from three digital panoramic units. GafChromic XR-QA2 films were placed between selected layers of the head and neck of a tis-sue-equivalent human skull (RANDO® phantom; The Phantom Labora-tory, Salem, NY). The effective dose was estimated using the 2007 ICRP formalism. The lowest effective dose of a CBCT unit was observed for ProMax 3D, FOV 4 X 5 cm (10 µSv), the highest for NewTom VGi, FOV 8 X 8 cm—high resolution (129 µSv). The range of effective doses for panoramic units measured was 8-14 µSv. STUDY III investigated the…

Subjects/Keywords: CBCT; OPTIMISATION; DOSAGE

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APA (6^th Edition):

Al-Okshi, A. (2017). Maxillofacial cone beam computed tomography (CBCT) : aspetcs on optimisation . (Thesis). Malmö University. Retrieved from http://hdl.handle.net/2043/23279

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Al-Okshi, Ayman. “Maxillofacial cone beam computed tomography (CBCT) : aspetcs on optimisation .” 2017. Thesis, Malmö University. Accessed February 17, 2020. http://hdl.handle.net/2043/23279.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Al-Okshi, Ayman. “Maxillofacial cone beam computed tomography (CBCT) : aspetcs on optimisation .” 2017. Web. 17 Feb 2020.

Vancouver:

Al-Okshi A. Maxillofacial cone beam computed tomography (CBCT) : aspetcs on optimisation . [Internet] [Thesis]. Malmö University; 2017. [cited 2020 Feb 17]. Available from: http://hdl.handle.net/2043/23279.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Al-Okshi A. Maxillofacial cone beam computed tomography (CBCT) : aspetcs on optimisation . [Thesis]. Malmö University; 2017. Available from: http://hdl.handle.net/2043/23279

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Oregon State University

6. Cammarata, Frank Anthony. Development and evaluation of guidelines for unit dose distribution systems.

Degree: MS, Pharmaceutical Science, 1969, Oregon State University

URL: http://hdl.handle.net/1957/46140

► Unit dose drug distribution systems have been established in a number of hospitals during the past several years. Such systems show promise in providing better… (more)

Subjects/Keywords: Drugs – Dosage

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APA (6^th Edition):

Cammarata, F. A. (1969). Development and evaluation of guidelines for unit dose distribution systems. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/46140

Chicago Manual of Style (16^th Edition):

Cammarata, Frank Anthony. “Development and evaluation of guidelines for unit dose distribution systems.” 1969. Masters Thesis, Oregon State University. Accessed February 17, 2020. http://hdl.handle.net/1957/46140.

MLA Handbook (7^th Edition):

Cammarata, Frank Anthony. “Development and evaluation of guidelines for unit dose distribution systems.” 1969. Web. 17 Feb 2020.

Vancouver:

Cammarata FA. Development and evaluation of guidelines for unit dose distribution systems. [Internet] [Masters thesis]. Oregon State University; 1969. [cited 2020 Feb 17]. Available from: http://hdl.handle.net/1957/46140.

Council of Science Editors:

Cammarata FA. Development and evaluation of guidelines for unit dose distribution systems. [Masters Thesis]. Oregon State University; 1969. Available from: http://hdl.handle.net/1957/46140

Oregon State University

7. Kingsley, Daniel Bruce. An analysis of the unit dose pharmacy system in small hospitals.

Degree: MS, Industrial and General Engineering, 1975, Oregon State University

URL: http://hdl.handle.net/1957/43737

► The traditional and the unit dose pharmacy distribution system were compared to determine which one, in thd opinion of hospital pharmacists and administrators, is best… (more)

Subjects/Keywords: Drugs – Dosage

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APA (6^th Edition):

Kingsley, D. B. (1975). An analysis of the unit dose pharmacy system in small hospitals. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/43737

Chicago Manual of Style (16^th Edition):

Kingsley, Daniel Bruce. “An analysis of the unit dose pharmacy system in small hospitals.” 1975. Masters Thesis, Oregon State University. Accessed February 17, 2020. http://hdl.handle.net/1957/43737.

MLA Handbook (7^th Edition):

Kingsley, Daniel Bruce. “An analysis of the unit dose pharmacy system in small hospitals.” 1975. Web. 17 Feb 2020.

Vancouver:

Kingsley DB. An analysis of the unit dose pharmacy system in small hospitals. [Internet] [Masters thesis]. Oregon State University; 1975. [cited 2020 Feb 17]. Available from: http://hdl.handle.net/1957/43737.

Council of Science Editors:

Kingsley DB. An analysis of the unit dose pharmacy system in small hospitals. [Masters Thesis]. Oregon State University; 1975. Available from: http://hdl.handle.net/1957/43737

Oregon State University

8. Brumley, Willis E. Commissioning of ADAC Pinnacle for IMRT utilizing solid compensators.

Degree: MS, Radiation Health Physics, 2008, Oregon State University

URL: http://hdl.handle.net/1957/8336

► Use of solid compensators is a very effective means of implementing IMRT on any linear accelerator. The standard practice has been IMRT delivery using accelerators… (more)

Subjects/Keywords: ADAC Pinnacle; Radiation – Dosage

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Brumley, W. E. (2008). Commissioning of ADAC Pinnacle for IMRT utilizing solid compensators. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/8336

Chicago Manual of Style (16^th Edition):

Brumley, Willis E. “Commissioning of ADAC Pinnacle for IMRT utilizing solid compensators.” 2008. Masters Thesis, Oregon State University. Accessed February 17, 2020. http://hdl.handle.net/1957/8336.

MLA Handbook (7^th Edition):

Brumley, Willis E. “Commissioning of ADAC Pinnacle for IMRT utilizing solid compensators.” 2008. Web. 17 Feb 2020.

Vancouver:

Brumley WE. Commissioning of ADAC Pinnacle for IMRT utilizing solid compensators. [Internet] [Masters thesis]. Oregon State University; 2008. [cited 2020 Feb 17]. Available from: http://hdl.handle.net/1957/8336.

Council of Science Editors:

Brumley WE. Commissioning of ADAC Pinnacle for IMRT utilizing solid compensators. [Masters Thesis]. Oregon State University; 2008. Available from: http://hdl.handle.net/1957/8336

9. Asma Khatoon. Development of analytical methods for the determination of pharmaceutically active compounds in commercial dosage forms; -.

Degree: Chemistry, 2013, Aligarh Muslim University

URL: http://shodhganga.inflibnet.ac.in/handle/10603/12873

►

The thesis entitled Development of analytical methods for the determination of pharmaceutically active compounds in commercial dosage forms is comprised of five chapters. First chapter… (more)

▼

The thesis entitled Development of analytical methods for the determination of pharmaceutically active compounds in commercial dosage forms is comprised of five chapters. First chapter describes a general introduction of the subject matter. The very relevant matters include: importance of drug analysis and its role in testing the medicine before it is made available to the public a note on drug impurity profiling a brief description of various analytical techniques and its applications in the quantitation of drug in pharmaceuticals and biological fluids a brief literature and chemical structures of the four drugs, i.e. Haloperidol, Doxepin Hydrochloride, Amitriptyline hydrochloride, Perindopril erbumine. an abundant and well-composed list of references is given at the end of the chapter taken from the world s leading scientific journals in the field. Second chapter describes spectrophotometric method for the determination of haloperidol in pharmaceutical preparations. The method is based on the formation of ion-pair complex between haloperidol and eriochrome black T at pH 1.85. The formed complex was extracted quantitatively into chloroform and measured at 510 nm. Infra red studies were performed to confirm the formation of ion-pair complex. Beer s law was obeyed in the concentration range of 2.0 - 9.0 and#956;g mL-1 with molar absorptivity of 2.67 × 104 L mol-1cm-1. The detection limit was found to be 0.18 and#956;g mL-1. Statistical comparison of the results of the proposed method with those of the reference method shows excellent agreement and indicates no significant difference in accuracy and precision. newlineThird chapter deals with the spectrofluorimetric determination of doxepin hydrochloride in commercial dosage forms. It is based on the formation of ion-pair complex between doxepin and alizarin red-S at pH 3.09. The ion pair complex was extracted in dichloromethane and the fluorescence intensity was measured at 560 nm after excitation at 490 nm. The optimum conditions for determination were also investigated.

References given chapter wise

Advisors/Committee Members: Nafisur Rahman.

Subjects/Keywords: Chemistry; commercial dosage forms

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APA (6^th Edition):

Khatoon, A. (2013). Development of analytical methods for the determination of pharmaceutically active compounds in commercial dosage forms; -. (Thesis). Aligarh Muslim University. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/12873

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Khatoon, Asma. “Development of analytical methods for the determination of pharmaceutically active compounds in commercial dosage forms; -.” 2013. Thesis, Aligarh Muslim University. Accessed February 17, 2020. http://shodhganga.inflibnet.ac.in/handle/10603/12873.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Khatoon, Asma. “Development of analytical methods for the determination of pharmaceutically active compounds in commercial dosage forms; -.” 2013. Web. 17 Feb 2020.

Vancouver:

Khatoon A. Development of analytical methods for the determination of pharmaceutically active compounds in commercial dosage forms; -. [Internet] [Thesis]. Aligarh Muslim University; 2013. [cited 2020 Feb 17]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/12873.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Khatoon A. Development of analytical methods for the determination of pharmaceutically active compounds in commercial dosage forms; -. [Thesis]. Aligarh Muslim University; 2013. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/12873

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

10. Aparna, Ponnala. Method Development for Impurities in some Multicomponent Dosage Forms and Cardiovascular Drugs; -.

Degree: Chemistry, 2013, Jawaharlal Nehru Technological University, Hyderabad

URL: http://shodhganga.inflibnet.ac.in/handle/10603/18837

►

Chapter-1 is about general introduction of impurities and method development. newlineChapter-2 describes about an unknown impurity formed in 50°C stability samples at 3 months in… (more)

Subjects/Keywords: Cardiovascular; Dosage; Drugs; Impurities; Multicomponent

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APA (6^th Edition):

Aparna, P. (2013). Method Development for Impurities in some Multicomponent Dosage Forms and Cardiovascular Drugs; -. (Thesis). Jawaharlal Nehru Technological University, Hyderabad. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/18837

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Aparna, Ponnala. “Method Development for Impurities in some Multicomponent Dosage Forms and Cardiovascular Drugs; -.” 2013. Thesis, Jawaharlal Nehru Technological University, Hyderabad. Accessed February 17, 2020. http://shodhganga.inflibnet.ac.in/handle/10603/18837.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Aparna, Ponnala. “Method Development for Impurities in some Multicomponent Dosage Forms and Cardiovascular Drugs; -.” 2013. Web. 17 Feb 2020.

Vancouver:

Aparna P. Method Development for Impurities in some Multicomponent Dosage Forms and Cardiovascular Drugs; -. [Internet] [Thesis]. Jawaharlal Nehru Technological University, Hyderabad; 2013. [cited 2020 Feb 17]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/18837.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Aparna P. Method Development for Impurities in some Multicomponent Dosage Forms and Cardiovascular Drugs; -. [Thesis]. Jawaharlal Nehru Technological University, Hyderabad; 2013. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/18837

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

11. Maram, . Sambasiva Rao. Design and Development of Oral Modified release dosage forms of Highly soluble drugs; -.

Degree: Pharmaceutical Sciences, 2013, Jawaharlal Nehru Technological University, Hyderabad

URL: http://shodhganga.inflibnet.ac.in/handle/10603/18958

►

The ultimate goal of the study was to develop a stable, cost effective modified release dosage form of highly soluble drugs such as newlineTrimetazidine dihydrochloride,… (more)

Subjects/Keywords: Design; Development; Dosage; Drugs; Modified

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APA (6^th Edition):

Maram, . S. R. (2013). Design and Development of Oral Modified release dosage forms of Highly soluble drugs; -. (Thesis). Jawaharlal Nehru Technological University, Hyderabad. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/18958

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Maram, Sambasiva Rao. “Design and Development of Oral Modified release dosage forms of Highly soluble drugs; -.” 2013. Thesis, Jawaharlal Nehru Technological University, Hyderabad. Accessed February 17, 2020. http://shodhganga.inflibnet.ac.in/handle/10603/18958.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Maram, Sambasiva Rao. “Design and Development of Oral Modified release dosage forms of Highly soluble drugs; -.” 2013. Web. 17 Feb 2020.

Vancouver:

Maram SR. Design and Development of Oral Modified release dosage forms of Highly soluble drugs; -. [Internet] [Thesis]. Jawaharlal Nehru Technological University, Hyderabad; 2013. [cited 2020 Feb 17]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/18958.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Maram SR. Design and Development of Oral Modified release dosage forms of Highly soluble drugs; -. [Thesis]. Jawaharlal Nehru Technological University, Hyderabad; 2013. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/18958

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Oregon State University

12. Patel, Aarti. Dose to the female breast from nuclear medicine and diagnostic radiology.

Degree: MS, Radiation Health Physics, 2008, Oregon State University

URL: http://hdl.handle.net/1957/9294

► There has been increased concern about radiation dose to the female breasts, with approximately 200,000 new breast cancers being diagnosed each year in the United… (more)

Subjects/Keywords: breast dose; Radiation – Dosage

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APA (6^th Edition):

Patel, A. (2008). Dose to the female breast from nuclear medicine and diagnostic radiology. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/9294

Chicago Manual of Style (16^th Edition):

Patel, Aarti. “Dose to the female breast from nuclear medicine and diagnostic radiology.” 2008. Masters Thesis, Oregon State University. Accessed February 17, 2020. http://hdl.handle.net/1957/9294.

MLA Handbook (7^th Edition):

Patel, Aarti. “Dose to the female breast from nuclear medicine and diagnostic radiology.” 2008. Web. 17 Feb 2020.

Vancouver:

Patel A. Dose to the female breast from nuclear medicine and diagnostic radiology. [Internet] [Masters thesis]. Oregon State University; 2008. [cited 2020 Feb 17]. Available from: http://hdl.handle.net/1957/9294.

Council of Science Editors:

Patel A. Dose to the female breast from nuclear medicine and diagnostic radiology. [Masters Thesis]. Oregon State University; 2008. Available from: http://hdl.handle.net/1957/9294

Penn State University

13. Elreda, Danny. Examining How The Ratio of Students on Campus to Counseling Center Staff Relates to Dosage and Counseling Center Treatment Effectiveness.

Degree: PhD, Counseling Psychology, 2014, Penn State University

URL: https://etda.libraries.psu.edu/catalog/22655

► It has been more than 30 years since the International Association of Counseling Services (IACS) established the student to staff ratio that defines the “standard… (more)

▼ It has been more than 30 years since the International Association of Counseling Services (IACS) established the student to staff ratio that defines the “standard of care” in university and college counseling centers. Since publication of this ratio in 1982, counseling centers have been advised to maintain minimum staffing ratios of one full-time equivalent (FTE) staff member to every 1,000-1,500 students on campus (Spivack et al., 2010). Yet the large majority of today’s counseling centers have ratios above those cutoffs, and the implications of this ratio for college students’ mental health have never been empirically assessed. This dissertation was the first to examine whether student to staff ratios were predictive of the number and frequency of clients’ sessions (dosage), and counseling center treatment effectiveness in reducing student distress. This dissertation employed data from the Center for Collegiate Mental Health (CCMH), a collaborative practice-research network that currently comprises more than 250 college counseling centers that use a common data management system (Hayes, Locke, & Castonguay, 2011). The present study focused on data from 2,041 students and 37 counseling centers from the 2010-2011 academic year. For each counseling center that participated in CCMH data collection, student to FTE staff ratios were computed as the total student population relative to number of full-time professional staff and paid trainees per counseling center. Change in student distress from intake to final session, as measured by the CCAPS-32, was used to quantify centers’ treatment effectiveness. Number of sessions that clients received from FTE staff, as well as the average length of time between sessions, were used to quantify center-level mean dosages. In general, findings indicated no significant associations between ratio, dosage, and effectiveness, though post hoc analyses provided some interesting, preliminary evidence about potential differences between public and private schools. Specifically, while private schools showed no relation between ratio and treatment effectiveness, public schools demonstrated the hypothesized relation: public schools with larger ratios saw a lower percentage of clients receiving effective treatment. Moreover, findings suggested that the majority of schools were able to provide relatively effective treatment despite falling outside of recommended ratio ranges. More broadly, results suggest that the relations between student to staff ratios, dosage, and counseling center treatment effectiveness are multi-faceted, likely influenced by an array of factors requiring further consideration.

Subjects/Keywords: Counseling centers; dosage; treatment; effectiveness

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APA (6^th Edition):

Elreda, D. (2014). Examining How The Ratio of Students on Campus to Counseling Center Staff Relates to Dosage and Counseling Center Treatment Effectiveness. (Doctoral Dissertation). Penn State University. Retrieved from https://etda.libraries.psu.edu/catalog/22655

Chicago Manual of Style (16^th Edition):

Elreda, Danny. “Examining How The Ratio of Students on Campus to Counseling Center Staff Relates to Dosage and Counseling Center Treatment Effectiveness.” 2014. Doctoral Dissertation, Penn State University. Accessed February 17, 2020. https://etda.libraries.psu.edu/catalog/22655.

MLA Handbook (7^th Edition):

Elreda, Danny. “Examining How The Ratio of Students on Campus to Counseling Center Staff Relates to Dosage and Counseling Center Treatment Effectiveness.” 2014. Web. 17 Feb 2020.

Vancouver:

Elreda D. Examining How The Ratio of Students on Campus to Counseling Center Staff Relates to Dosage and Counseling Center Treatment Effectiveness. [Internet] [Doctoral dissertation]. Penn State University; 2014. [cited 2020 Feb 17]. Available from: https://etda.libraries.psu.edu/catalog/22655.

Council of Science Editors:

Elreda D. Examining How The Ratio of Students on Campus to Counseling Center Staff Relates to Dosage and Counseling Center Treatment Effectiveness. [Doctoral Dissertation]. Penn State University; 2014. Available from: https://etda.libraries.psu.edu/catalog/22655

Montana Tech

14. Hargrove, Suzanne Abran. Comparison of American and French posology.

Degree: MS, 1947, Montana Tech

URL: https://scholarworks.umt.edu/etd/6261

Subjects/Keywords: Drugs Dosage.

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APA (6^th Edition):

Hargrove, S. A. (1947). Comparison of American and French posology. (Masters Thesis). Montana Tech. Retrieved from https://scholarworks.umt.edu/etd/6261

Chicago Manual of Style (16^th Edition):

Hargrove, Suzanne Abran. “Comparison of American and French posology.” 1947. Masters Thesis, Montana Tech. Accessed February 17, 2020. https://scholarworks.umt.edu/etd/6261.

MLA Handbook (7^th Edition):

Hargrove, Suzanne Abran. “Comparison of American and French posology.” 1947. Web. 17 Feb 2020.

Vancouver:

Hargrove SA. Comparison of American and French posology. [Internet] [Masters thesis]. Montana Tech; 1947. [cited 2020 Feb 17]. Available from: https://scholarworks.umt.edu/etd/6261.

Council of Science Editors:

Hargrove SA. Comparison of American and French posology. [Masters Thesis]. Montana Tech; 1947. Available from: https://scholarworks.umt.edu/etd/6261

Oregon State University

15. Lentsch, Jack Wayne. Absorbed dose from X rays in soft tissue adjacent to bone measured by induced conductivity in polyethylene films.

Degree: MS, General Science, 1966, Oregon State University

URL: http://hdl.handle.net/1957/48161

► The X-ray dose absorbed in soft tissue located near plane bone interfaces and in parallel-slab bone cavities was measured experimentally with a polyethylene-film dosimeter. The… (more)

▼ The X-ray dose absorbed in soft tissue located near plane bone interfaces and in parallel-slab bone cavities was measured experimentally with a polyethylene-film dosimeter. The dose absorbed in soft tissue adjacent to plane bone interfaces was measured by placing a 12.7 micron film of polyethylene, upon which were deposited graphite electrodes, in contact with bone-equivalent disks of Shonka plastic. The dose was measured both as a function of X-ray quality and distance of the tissue-equivalent polyethylene away from the bone interface. The dose in finite soft tissue layers next to bone was also measured as a function of X-ray quality. The results indicated that the soft tissue dose in finite layers next to the bone was greater than that remote from the bone. At the lower effective X-ray energies the dose very close to the bone was considerably higher than for the higher effective X-ray energies. At higher effective X-ray energies, however, the increased dose effect extended to a greater depth in the soft tissue. At effective energies greater than 177 keV electronic equilibrium was obtained, and the dose was the same for the adjacent and distant soft tissue. Comparisons were made of the experimentally measured doses in soft tissue near plane bone interfaces with calculated doses for monoenergetic photons. It was observed that at effective X-ray energies below approximately 60 keV the experimental results gave higher dose values than the theoretical values. However, at higher effective X-ray energies there was good agreement between the experimental and theoretical results. It was concluded that X-ray spectral considerations were mainly responsible for the deviations at lower effective energies. The results of this study indicated that when one wishes to calculate the dose absorbed in soft tissue adjacent to plane bone interfaces at low effective X-ray energies, the theory cannot be relied upon and experimentally determined doses such as those shown herein should be used instead. The X-ray dose in soft tissue elements interposed between parallel slabs of bone was measured in the same manner as the dose in soft tissue adjacent to plane bone interfaces. However, due to experimental difficulties in simulating this bone-tissue orientation, it was not possible to make reasonable dose measurements. Advisors/Committee Members: Trout, E. Dale (advisor).

Subjects/Keywords: Radiation – Dosage

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APA (6^th Edition):

Lentsch, J. W. (1966). Absorbed dose from X rays in soft tissue adjacent to bone measured by induced conductivity in polyethylene films. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/48161

Chicago Manual of Style (16^th Edition):

Lentsch, Jack Wayne. “Absorbed dose from X rays in soft tissue adjacent to bone measured by induced conductivity in polyethylene films.” 1966. Masters Thesis, Oregon State University. Accessed February 17, 2020. http://hdl.handle.net/1957/48161.

MLA Handbook (7^th Edition):

Lentsch, Jack Wayne. “Absorbed dose from X rays in soft tissue adjacent to bone measured by induced conductivity in polyethylene films.” 1966. Web. 17 Feb 2020.

Vancouver:

Lentsch JW. Absorbed dose from X rays in soft tissue adjacent to bone measured by induced conductivity in polyethylene films. [Internet] [Masters thesis]. Oregon State University; 1966. [cited 2020 Feb 17]. Available from: http://hdl.handle.net/1957/48161.

Council of Science Editors:

Lentsch JW. Absorbed dose from X rays in soft tissue adjacent to bone measured by induced conductivity in polyethylene films. [Masters Thesis]. Oregon State University; 1966. Available from: http://hdl.handle.net/1957/48161

Oregon State University

16. Egan, Alexander J. Development of an accurate Monte Carlo treatment plan calculation framework for the purpose of developing dose calculation error predictors for a widely implemented clinical algorithm.

Degree: PhD, Medical Physics, 2014, Oregon State University

URL: http://hdl.handle.net/1957/48897

► Monte Carlo (MC) algorithms are widely accepted as the most accurate method to calculate dose in a patient geometry. For this work the EGSnrc MC… (more)

▼ Monte Carlo (MC) algorithms are widely accepted as the most accurate method to calculate dose in a patient geometry. For this work the EGSnrc MC code was used as a benchmark for the identification of dose calculation errors produced by the widely implemented analytical anisotropic algorithm (AAA). By correlating the location and magnitude of these errors with the physical conditions under which AAA is known to fail, a set of error prediction methods was developed which can help to identify clinical plans that are at high risk for AAA dose calculation errors. Once these plans are identified, they can be recalculated with a more accurate algorithm. First, in order to calculate clinical treatment plans with MC, a treatment plan calculation framework (MCTPCF) was developed and validated. The underlying beam model used in the MCTPCF was thoroughly benchmarked against a standard open field data set. Radiochromic film measurements were then used to validate the geometry of the employed MC multileaf collimator (MLC) model. Mechanical functionality of the MCTPCF was verified by calculating several highly modulated clinical treatment plans and comparing them with AAA calculations. Next, three novel error prediction algorithms were developed and validated to a limited extent. The first, designated the field size index (FSI), identifies regions in the treatment plan space where many small fields or blocks overlap, leading to a build-up of beam modeling and volume averaging errors. The second, designated the heterogeneous scatter index (HSI), identifies regions within the electron density distribution where the AAA rectilinear kernel scaling approximation is stressed. The third, designated the low-density index (LDI), identifies regions of very low electron density where AAA is known to overestimate dose. An open field beam model for the 6MV Varian Clinac has been fully parameterized and is able to calculate dose to within 1.3% and 1.0 mm DTA (σ[mean] = 0.3%). The MCTPCF has been shown to accurately calculate highly modulated, multiple field treatments. FSI calculations show excellent agreement with MC/AAA deviations in highly modulated MLC fields in water, and to a lesser extent in patient geometry RapidArc treatments. The LDI accurately predicts AAA overdosing for simple geometries, however for the lung case investigated other sources of error made identifying any correlation a challenge. The theoretical structure of the HSI has been developed, however its implementation is still underway. An accurate MC based treatment plan calculation tool has been developed and validated. Three novel error prediction algorithms have been developed, two of which have been validated for homogenous geometries. In particular, the FSI shows promise as both a direct predictor of AAA error, and also as a general treatment plan complexity index. With sufficient benchmarking, these methods may be developed into a clinical tool that can identify treatment plans that are at high risk for AAA dose calculation errors. Advisors/Committee Members: Laub, Wolfram (advisor), Palmer, Camille (committee member).

Subjects/Keywords: Monte Carlo; Radiation – Dosage

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APA (6^th Edition):

Egan, A. J. (2014). Development of an accurate Monte Carlo treatment plan calculation framework for the purpose of developing dose calculation error predictors for a widely implemented clinical algorithm. (Doctoral Dissertation). Oregon State University. Retrieved from http://hdl.handle.net/1957/48897

Chicago Manual of Style (16^th Edition):

Egan, Alexander J. “Development of an accurate Monte Carlo treatment plan calculation framework for the purpose of developing dose calculation error predictors for a widely implemented clinical algorithm.” 2014. Doctoral Dissertation, Oregon State University. Accessed February 17, 2020. http://hdl.handle.net/1957/48897.

MLA Handbook (7^th Edition):

Egan, Alexander J. “Development of an accurate Monte Carlo treatment plan calculation framework for the purpose of developing dose calculation error predictors for a widely implemented clinical algorithm.” 2014. Web. 17 Feb 2020.

Vancouver:

Egan AJ. Development of an accurate Monte Carlo treatment plan calculation framework for the purpose of developing dose calculation error predictors for a widely implemented clinical algorithm. [Internet] [Doctoral dissertation]. Oregon State University; 2014. [cited 2020 Feb 17]. Available from: http://hdl.handle.net/1957/48897.

Council of Science Editors:

Egan AJ. Development of an accurate Monte Carlo treatment plan calculation framework for the purpose of developing dose calculation error predictors for a widely implemented clinical algorithm. [Doctoral Dissertation]. Oregon State University; 2014. Available from: http://hdl.handle.net/1957/48897

Oregon State University

17. Chorzempa, Mary André, Sister. Ionizing radiation and its chemical effects : a historical study of chemical dosimetry (1902-1962).

Degree: PhD, General Science, 1970, Oregon State University

URL: http://hdl.handle.net/1957/45710

► Chemical dosimetry developed in response to needs created by developments in the field of high-energy radiation. Shortly after the discovery of X-rays in 1895 and… (more)

▼ Chemical dosimetry developed in response to needs created by developments in the field of high-energy radiation. Shortly after the discovery of X-rays in 1895 and of radioactivity in 1896, the deleterious effects of ionizing radiation were recognized. To guard against the injurious effects of radiation in medical application, dose-measuring methods were considered necessary. The early dosimetric methods were based on what at the time were taken to be the chemical effects of ionizing radiation. In 1902, Guido Holzknecht (1872-1931), a Viennese physician, suggested a method of dosimetry which was based on the coloration of a salt due to irradiation. His proposal, the first of its kind, was followed within about five years by a number of others which were made by other physicians and radiologists and which were based on some visible chemical change. Subsequent developments in chemical dosimetry until about 1915 were concerned mainly with the calibrated scales used to relate the chemical change to dose, the problem being a lack of a radiation unit of dose. Further investigations of chemical systems for dosimetry were not made, however, until in the 1920's. In the meantime ionization methods of dosimetry became popular, although some of the earlier proposed chemical dosimeters were widely in use. The renewal of interest in the chemical effects of ionizing radiation in the 1920's stemmed from the extensive radiobiological research that was conducted owing to the expanded application of higher-energy X-ray units in medicine and in industry. From the research done to understand better the mechanisms underlying biochemical processes, there proceeded several dosimetric systems. The one that proved most reliable was the ferrous sulfate system recommended in 1927 by the biophysicist Hugo Fricke (b. 1892). This renewed research on the chemical effects of ionizing radiation also made some significant contributions for future developments in chemical dosimetry. Most fundamental, both to the developing theories of radiation chemistry as well as to the formulation of many dosimetric systems in the post-World War II period, was the observation made by Fricke and associates that the primary action of the radiation was on the solvent rather than the solute. The discovery of the neutron and of artificial radioactivity and the development of accelerating devices in the 1930's provided for still further application of ionizing radiation in medicine and in industry which increased the number of persons whose occupation was a source of radiation exposure. A growing concern for the protection of personnel contributed to attempts at standardizing dosage measurements. Although formal standardization began in 1928 when the roentgen was officially defined as a radiation unit by the International Commission on Radiological Units, it was not until 1962 that the rad was officially restricted as a unit of dose and the roentgen as a unit of exposure. The precision of the terminology contributed to more… Advisors/Committee Members: Morris, Robert J. (advisor).

Subjects/Keywords: Radiation – Dosage

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APA (6^th Edition):

Chorzempa, Mary André, S. (1970). Ionizing radiation and its chemical effects : a historical study of chemical dosimetry (1902-1962). (Doctoral Dissertation). Oregon State University. Retrieved from http://hdl.handle.net/1957/45710

Chicago Manual of Style (16^th Edition):

Chorzempa, Mary André, Sister. “Ionizing radiation and its chemical effects : a historical study of chemical dosimetry (1902-1962).” 1970. Doctoral Dissertation, Oregon State University. Accessed February 17, 2020. http://hdl.handle.net/1957/45710.

MLA Handbook (7^th Edition):

Chorzempa, Mary André, Sister. “Ionizing radiation and its chemical effects : a historical study of chemical dosimetry (1902-1962).” 1970. Web. 17 Feb 2020.

Vancouver:

Chorzempa, Mary André S. Ionizing radiation and its chemical effects : a historical study of chemical dosimetry (1902-1962). [Internet] [Doctoral dissertation]. Oregon State University; 1970. [cited 2020 Feb 17]. Available from: http://hdl.handle.net/1957/45710.

Council of Science Editors:

Chorzempa, Mary André S. Ionizing radiation and its chemical effects : a historical study of chemical dosimetry (1902-1962). [Doctoral Dissertation]. Oregon State University; 1970. Available from: http://hdl.handle.net/1957/45710

Oregon State University

18. Denovan, James Thomas. Dosimetry considerations in the irradiation of biological populations.

Degree: MS, General Science, 1967, Oregon State University

URL: http://hdl.handle.net/1957/47230

► The effects of changes in dosimetry conditions on the radiation sensitivity of a constant biological population were determined. The organism used for this study was… (more)

Subjects/Keywords: Radiation – Dosage

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APA (6^th Edition):

Denovan, J. T. (1967). Dosimetry considerations in the irradiation of biological populations. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/47230

Chicago Manual of Style (16^th Edition):

Denovan, James Thomas. “Dosimetry considerations in the irradiation of biological populations.” 1967. Masters Thesis, Oregon State University. Accessed February 17, 2020. http://hdl.handle.net/1957/47230.

MLA Handbook (7^th Edition):

Denovan, James Thomas. “Dosimetry considerations in the irradiation of biological populations.” 1967. Web. 17 Feb 2020.

Vancouver:

Denovan JT. Dosimetry considerations in the irradiation of biological populations. [Internet] [Masters thesis]. Oregon State University; 1967. [cited 2020 Feb 17]. Available from: http://hdl.handle.net/1957/47230.

Council of Science Editors:

Denovan JT. Dosimetry considerations in the irradiation of biological populations. [Masters Thesis]. Oregon State University; 1967. Available from: http://hdl.handle.net/1957/47230

Oregon State University

19. Braby, L. A. Ionization in microscopic volumes irradiated by energetic photons.

Degree: PhD, General Science, 1971, Oregon State University

URL: http://hdl.handle.net/1957/23012

► The energy absorbed by microscopic volumes exposed to ionizing radiation is not well represented by the average dose due to the small number of discrete… (more)

Subjects/Keywords: Radiation – Dosage

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APA (6^th Edition):

Braby, L. A. (1971). Ionization in microscopic volumes irradiated by energetic photons. (Doctoral Dissertation). Oregon State University. Retrieved from http://hdl.handle.net/1957/23012

Chicago Manual of Style (16^th Edition):

Braby, L A. “Ionization in microscopic volumes irradiated by energetic photons.” 1971. Doctoral Dissertation, Oregon State University. Accessed February 17, 2020. http://hdl.handle.net/1957/23012.

MLA Handbook (7^th Edition):

Braby, L A. “Ionization in microscopic volumes irradiated by energetic photons.” 1971. Web. 17 Feb 2020.

Vancouver:

Braby LA. Ionization in microscopic volumes irradiated by energetic photons. [Internet] [Doctoral dissertation]. Oregon State University; 1971. [cited 2020 Feb 17]. Available from: http://hdl.handle.net/1957/23012.

Council of Science Editors:

Braby LA. Ionization in microscopic volumes irradiated by energetic photons. [Doctoral Dissertation]. Oregon State University; 1971. Available from: http://hdl.handle.net/1957/23012

Rutgers University

20. Karry-Rivera, Krizia Marie, 1986-. Flexible continuous manufacturing platforms for solid dispersion formulations.

Degree: PhD, Chemical and Biochemical Engineering, 2015, Rutgers University

URL: https://rucore.libraries.rutgers.edu/rutgers-lib/48538/

►

In 2013 16,000 people died in the US due to overdose from prescription drugs and synthetic narcotics. As of that same year, 90% of new… (more)

▼

In 2013 16,000 people died in the US due to overdose from prescription drugs and synthetic narcotics. As of that same year, 90% of new molecular entities in the pharmaceutical drug pipeline are classified as poor water-soluble. The work in this dissertation aims to design, develop and validate platforms that solubilize weak acids and can potentially deter drug abuse. These platforms are based on processing solid dispersions via solvent-casting and hot-melt extrusion methods to produce oral transmucosal films and melt tablets. To develop these platforms, nanocrystalline suspensions and glassy solutions were solvent-casted in the form of films after physicochemical characterizations of drug-excipient interactions and design of experiment approaches. A second order model was fitted to the emulsion diffusion process to predict average nanoparticle size and for process optimization. To further validate the manufacturing flexibility of the formulations, glassy solutions were also extruded and molded into tablets. This process included a systematic quality-by-design (QbD) approach that served to identify the factors affecting the critical quality attributes (CQAs) of the melt tablets. These products, due to their novelty, lack discriminatory performance tests that serve as predictors to their compliance and stability. Consequently, Process Analytical Technology (PAT) tools were integrated into the continuous manufacturing platform for films. Near-infrared (NIR) spectroscopy, including chemical imaging, combined with deconvolution algorithms were utilized for a holistic assessment of the effect of formulation and process variables on the product’s CQAs. Biorelevant dissolution protocols were then established to improve the in-vivo in-vitro correlation of the oral transmucosal films. In conclusion, the work in this dissertation supports the delivery of poor-water soluble drugs in products that may deter abuse. Drug nanocrystals ensured high bioavailability, while glassy solutions enabled drug solubilization in polymer matrices. PAT tools helped in characterizing the micro and macro structure of the product while also used as a control strategy for manufacturing. The systematic QbD assessment enabled identification of the variables that significantly affected melt tablet performance and their potential as an abuse deterrent product. Being that these glassy products are novel systems, biorelevant protocols for testing dissolution performance of films were also developed.

Advisors/Committee Members: Michniak-Kohn, Bozena (chair), Muzzio, Fernando J (co-chair), Ierapetritou, Marianthi (internal member), Romanski, Frank (outside member).

Subjects/Keywords: Solid dosage forms; Pharmaceutical chemistry

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APA (6^th Edition):

Karry-Rivera, Krizia Marie, 1. (2015). Flexible continuous manufacturing platforms for solid dispersion formulations. (Doctoral Dissertation). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/48538/

Chicago Manual of Style (16^th Edition):

Karry-Rivera, Krizia Marie, 1986-. “Flexible continuous manufacturing platforms for solid dispersion formulations.” 2015. Doctoral Dissertation, Rutgers University. Accessed February 17, 2020. https://rucore.libraries.rutgers.edu/rutgers-lib/48538/.

MLA Handbook (7^th Edition):

Karry-Rivera, Krizia Marie, 1986-. “Flexible continuous manufacturing platforms for solid dispersion formulations.” 2015. Web. 17 Feb 2020.

Vancouver:

Karry-Rivera, Krizia Marie 1. Flexible continuous manufacturing platforms for solid dispersion formulations. [Internet] [Doctoral dissertation]. Rutgers University; 2015. [cited 2020 Feb 17]. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/48538/.

Council of Science Editors:

Karry-Rivera, Krizia Marie 1. Flexible continuous manufacturing platforms for solid dispersion formulations. [Doctoral Dissertation]. Rutgers University; 2015. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/48538/

Rutgers University

21. Frech-Tamas, Feride, 1965-. Impact of medication burden on adherence with antihypertensive drugs.

Degree: PhD, Public Health, 2010, Rutgers University

URL: http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000056348

►

Antihypertensive drug adherence is key in achieving blood pressure control and preventing cardiovascular complications. The objective of this study was to understand how pill burden,… (more)

▼

Antihypertensive drug adherence is key in achieving blood pressure control and preventing cardiovascular complications. The objective of this study was to understand how pill burden, age and comorbid conditions impact antihypertensive medication compliance. This retrospective study used MarketScan claims to identify continuously enrolled adults with newly diagnosed hypertension, follow‐up  6‐month pre‐ and 12–month post‐index antihypertensive prescription. Pill burden was defined as total number of prescriptions per month and/or doses per day. Medication possession ratio (MPR), defined as total number of index antihypertensive days’ supply divided by 365, was a proxy for compliance. MPR ≥ 0.80 was classified as high. Descriptive statistics were conducted for 27 variables including sociodemographic characteristics, comorbid conditions, health care resource utilization and costs. Logistic regression analysis was run (SAS, version 8.2, Cary, NC). Mean age was 53 years for 68,538 study subjects and 56% were female. Diabetes (18%) and other forms of heart disease (14%) were most prevalent. Most subjects were full‐time employees (64%), working in manufacturing/durable goods (36%) or transportation/communications/utilities (21%), and residing in the South (41%) or North Central (28%) United States. Preferred provider organizations (41%) and comprehensive benefit plans (23%) provided coverage for most subjects. Approximately 25% of subjects received diuretics, 21% angiotensin‐converting enzyme inhibitors, 20% beta‐blockers, 17% fixed‐dose combinations, 9% calciumchannel blockers, and 8% angiotensin receptor blockers (ARBs). Total index antihypertensive copay was lowest for diuretics (48.71) and highest for ARBs (98.12). Mean number of doses per day (excluding antihypertensive prescriptions) was 1.3 and number of prescriptions per month (excluding antihypertensive prescriptions) was 1.85. Mean MPR was 0.70 and 57% of subjects were highly compliant with antihypertensive medications. Likelihood of compliance decreased by 10% per additional dose per day, increased by 22.5% per additional prescription per month (excluding antihypertensive medications), decreased by 10% per additional comorbid conditions, increased by 0.6% per additional year of age, by 1.1% per dollar increase in total copay and was 9% greater for males (p < 0.0001). Increasing doses per day, comorbid conditions and being female had a negative impact on compliance with antihypertensive medications and may assist in targeting populations for quality improvement initiatives.

Advisors/Committee Members: Frech-Tamas, Feride, 1965- (author), Schneider, Dona (chair), RHOADS, GEORGE (internal member), Suh, Dong-Churl (internal member), Arcona, Stephen (outside member).

Subjects/Keywords: Hypotensive agents – Administration; Drugs – Dosage

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APA (6^th Edition):

Frech-Tamas, Feride, 1. (2010). Impact of medication burden on adherence with antihypertensive drugs. (Doctoral Dissertation). Rutgers University. Retrieved from http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000056348

Chicago Manual of Style (16^th Edition):

Frech-Tamas, Feride, 1965-. “Impact of medication burden on adherence with antihypertensive drugs.” 2010. Doctoral Dissertation, Rutgers University. Accessed February 17, 2020. http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000056348.

MLA Handbook (7^th Edition):

Frech-Tamas, Feride, 1965-. “Impact of medication burden on adherence with antihypertensive drugs.” 2010. Web. 17 Feb 2020.

Vancouver:

Frech-Tamas, Feride 1. Impact of medication burden on adherence with antihypertensive drugs. [Internet] [Doctoral dissertation]. Rutgers University; 2010. [cited 2020 Feb 17]. Available from: http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000056348.

Council of Science Editors:

Frech-Tamas, Feride 1. Impact of medication burden on adherence with antihypertensive drugs. [Doctoral Dissertation]. Rutgers University; 2010. Available from: http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000056348

Princeton University

22. Watson, Colin. Dynamics Of Early Zygotic Dosage Compensation and a Characterization of Spiroplasmas Role in Drosophila Male-Killing .

Degree: PhD, 2016, Princeton University

URL: http://arks.princeton.edu/ark:/88435/dsp01tb09j815t

► Characterizing Early Zygotic Dosage Compensation in Drosophila melanogaster using RNA-Seq Sexual reproduction in flies, mammals, and worms results in males and females receiving different numbers… (more)

▼ Characterizing Early Zygotic Dosage Compensation in Drosophila melanogaster using RNA-Seq Sexual reproduction in flies, mammals, and worms results in males and females receiving different numbers of X chromosomes. A chromosome wide regulatory process termed dosage compensation counteracts the differences in X-linked gene expression between sexes by balancing X-chromosome transcript levels. In Drosophila melanogaster, the Dosage Compensation Complex (DCC) forms in the presence of Msl-2 and activates a two-fold increase in gene expression. However multiple questions still remain regarding the function of the DCC as recent studies indicate the presence of an alternative dosage compensation mechanism. Sex lethal (Sxl), an RNA binding protein involved in sex determination is believed to play a role in this alternative model by regulating X-linked female transcripts. In this study we will examine the mechanism behind early zygotic dosage compensation using a novel high-throughput approach to sort male and female embryos during early embryogenesis. We use RNA-Seq to measure zygotic expression levels in male and female embryos. We then characterize Sxl and Msl-1 loss-of-function mutants to determine the mechanism behind early dosage compensation. Our study intends to further our understanding of sex specific transcription on a global scale during early Drosophila development. Determining Spiroplasma MSRO’s role in Drosophila melanogaster male lethality Spiroplasma MSRO are maternally transmitted bacteria that infect Drosophila melanogaster and induce apoptosis in male embryos during early embryogenesis. Previous reports have implicated the male dosage compensation complex (DCC) as a factor in male lethality as the loss of any DCC gene suppresses Spiroplasma induced apoptosis. In this study we characterize Spiroplasma’s impact on the male embryo’s molecular and morphogenetic development. We use RNA-Seq to measure transcript levels in infected male and female embryos during early embryogenesis. To determine if the loss of the dosage compensation system rescues transcript mis-regulation we quantify gene expression in homozygous Msl-1 embryos. We show that mis-regulation is sex specific and that Drosophila autosomal and X-linked genes are affected. We demonstrate that the loss of DCC functionality rescues transcript mis-regulation in infected male embryos. Our study intends to further our understanding of sex specific host-symbiont interactions. Advisors/Committee Members: Wieschaus, Eric (advisor).

Subjects/Keywords: Dosage Compensation; RNA-Seq; Spiroplasma

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APA (6^th Edition):

Watson, C. (2016). Dynamics Of Early Zygotic Dosage Compensation and a Characterization of Spiroplasmas Role in Drosophila Male-Killing . (Doctoral Dissertation). Princeton University. Retrieved from http://arks.princeton.edu/ark:/88435/dsp01tb09j815t

Chicago Manual of Style (16^th Edition):

Watson, Colin. “Dynamics Of Early Zygotic Dosage Compensation and a Characterization of Spiroplasmas Role in Drosophila Male-Killing .” 2016. Doctoral Dissertation, Princeton University. Accessed February 17, 2020. http://arks.princeton.edu/ark:/88435/dsp01tb09j815t.

MLA Handbook (7^th Edition):

Watson, Colin. “Dynamics Of Early Zygotic Dosage Compensation and a Characterization of Spiroplasmas Role in Drosophila Male-Killing .” 2016. Web. 17 Feb 2020.

Vancouver:

Watson C. Dynamics Of Early Zygotic Dosage Compensation and a Characterization of Spiroplasmas Role in Drosophila Male-Killing . [Internet] [Doctoral dissertation]. Princeton University; 2016. [cited 2020 Feb 17]. Available from: http://arks.princeton.edu/ark:/88435/dsp01tb09j815t.

Council of Science Editors:

Watson C. Dynamics Of Early Zygotic Dosage Compensation and a Characterization of Spiroplasmas Role in Drosophila Male-Killing . [Doctoral Dissertation]. Princeton University; 2016. Available from: http://arks.princeton.edu/ark:/88435/dsp01tb09j815t

23. Supenporn Aksornwong. Predictability of theophylline dosage on patients with some diseases and drugs affecting pharmacokinetic parameters in Maharaj Nahkonsrithammaraj Hospital .

Degree: Prince of Songkla University Faculty of Pharmaceutical Sciences (Clinical Pharmacy), 2002, Prince of Songkla University

URL: http://kb.psu.ac.th/psukb/handle/2553/1333

Subjects/Keywords: Theophylline Dosage; Drugs Dosage

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APA (6^th Edition):

Aksornwong, S. (2002). Predictability of theophylline dosage on patients with some diseases and drugs affecting pharmacokinetic parameters in Maharaj Nahkonsrithammaraj Hospital . (Thesis). Prince of Songkla University. Retrieved from http://kb.psu.ac.th/psukb/handle/2553/1333

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Aksornwong, Supenporn. “Predictability of theophylline dosage on patients with some diseases and drugs affecting pharmacokinetic parameters in Maharaj Nahkonsrithammaraj Hospital .” 2002. Thesis, Prince of Songkla University. Accessed February 17, 2020. http://kb.psu.ac.th/psukb/handle/2553/1333.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Aksornwong, Supenporn. “Predictability of theophylline dosage on patients with some diseases and drugs affecting pharmacokinetic parameters in Maharaj Nahkonsrithammaraj Hospital .” 2002. Web. 17 Feb 2020.

Vancouver:

Aksornwong S. Predictability of theophylline dosage on patients with some diseases and drugs affecting pharmacokinetic parameters in Maharaj Nahkonsrithammaraj Hospital . [Internet] [Thesis]. Prince of Songkla University; 2002. [cited 2020 Feb 17]. Available from: http://kb.psu.ac.th/psukb/handle/2553/1333.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Aksornwong S. Predictability of theophylline dosage on patients with some diseases and drugs affecting pharmacokinetic parameters in Maharaj Nahkonsrithammaraj Hospital . [Thesis]. Prince of Songkla University; 2002. Available from: http://kb.psu.ac.th/psukb/handle/2553/1333

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Ghana

24. Sackey, T.A. Cancer Risk Assessment of Patients Undergoing Computed Tomography Examination at the Korle-Bu Teaching Hospital (KBTH) .

Degree: 2015, University of Ghana

URL: http://ugspace.ug.edu.gh/handle/123456789/22588

► The aim of this study is to estimate the effective dose and assess the lifetime attributable risk of cancer incidence of patients undergoing computed tomography… (more)

Subjects/Keywords: Cancer; Computed Tomography Examination; Dosage; Ghana

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APA (6^th Edition):

Sackey, T. A. (2015). Cancer Risk Assessment of Patients Undergoing Computed Tomography Examination at the Korle-Bu Teaching Hospital (KBTH) . (Masters Thesis). University of Ghana. Retrieved from http://ugspace.ug.edu.gh/handle/123456789/22588

Chicago Manual of Style (16^th Edition):

Sackey, T A. “Cancer Risk Assessment of Patients Undergoing Computed Tomography Examination at the Korle-Bu Teaching Hospital (KBTH) .” 2015. Masters Thesis, University of Ghana. Accessed February 17, 2020. http://ugspace.ug.edu.gh/handle/123456789/22588.

MLA Handbook (7^th Edition):

Sackey, T A. “Cancer Risk Assessment of Patients Undergoing Computed Tomography Examination at the Korle-Bu Teaching Hospital (KBTH) .” 2015. Web. 17 Feb 2020.

Vancouver:

Sackey TA. Cancer Risk Assessment of Patients Undergoing Computed Tomography Examination at the Korle-Bu Teaching Hospital (KBTH) . [Internet] [Masters thesis]. University of Ghana; 2015. [cited 2020 Feb 17]. Available from: http://ugspace.ug.edu.gh/handle/123456789/22588.

Council of Science Editors:

Sackey TA. Cancer Risk Assessment of Patients Undergoing Computed Tomography Examination at the Korle-Bu Teaching Hospital (KBTH) . [Masters Thesis]. University of Ghana; 2015. Available from: http://ugspace.ug.edu.gh/handle/123456789/22588

Oregon State University

25. Hsu, Huey-yuh. Dissolution and bioavailability of immediate and sustained release cold and cough dosage forms.

Degree: MS, Pharmacy, 1987, Oregon State University

URL: http://hdl.handle.net/1957/40853

► A high-pressure liquid chromatography method based on reported literature was developed for the quantitative analysis of chlorpheniramine, pseudoephedrine, phenylpropanolamine and acetaminophen in dissolution fluids and… (more)

Subjects/Keywords: Drugs – Dosage forms

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APA (6^th Edition):

Hsu, H. (1987). Dissolution and bioavailability of immediate and sustained release cold and cough dosage forms. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/40853

Chicago Manual of Style (16^th Edition):

Hsu, Huey-yuh. “Dissolution and bioavailability of immediate and sustained release cold and cough dosage forms.” 1987. Masters Thesis, Oregon State University. Accessed February 17, 2020. http://hdl.handle.net/1957/40853.

MLA Handbook (7^th Edition):

Hsu, Huey-yuh. “Dissolution and bioavailability of immediate and sustained release cold and cough dosage forms.” 1987. Web. 17 Feb 2020.

Vancouver:

Hsu H. Dissolution and bioavailability of immediate and sustained release cold and cough dosage forms. [Internet] [Masters thesis]. Oregon State University; 1987. [cited 2020 Feb 17]. Available from: http://hdl.handle.net/1957/40853.

Council of Science Editors:

Hsu H. Dissolution and bioavailability of immediate and sustained release cold and cough dosage forms. [Masters Thesis]. Oregon State University; 1987. Available from: http://hdl.handle.net/1957/40853

26. Dasari, Varun. Design and Evaluation of Floating Dosage Forms as Controlled Release Modules; -.

Degree: Pharmaceutical Sciences, 2012, Jawaharlal Nehru Technological University, Hyderabad

URL: http://shodhganga.inflibnet.ac.in/handle/10603/19041

►

Human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS), commonly referred to as HIV/AIDS, constitute one of the most serious infectious disease challenges… (more)

Subjects/Keywords: Controlled; Design; Dosage; Evaluation; Floating; Modules

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APA (6^th Edition):

Dasari, V. (2012). Design and Evaluation of Floating Dosage Forms as Controlled Release Modules; -. (Thesis). Jawaharlal Nehru Technological University, Hyderabad. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/19041

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Dasari, Varun. “Design and Evaluation of Floating Dosage Forms as Controlled Release Modules; -.” 2012. Thesis, Jawaharlal Nehru Technological University, Hyderabad. Accessed February 17, 2020. http://shodhganga.inflibnet.ac.in/handle/10603/19041.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Dasari, Varun. “Design and Evaluation of Floating Dosage Forms as Controlled Release Modules; -.” 2012. Web. 17 Feb 2020.

Vancouver:

Dasari V. Design and Evaluation of Floating Dosage Forms as Controlled Release Modules; -. [Internet] [Thesis]. Jawaharlal Nehru Technological University, Hyderabad; 2012. [cited 2020 Feb 17]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/19041.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Dasari V. Design and Evaluation of Floating Dosage Forms as Controlled Release Modules; -. [Thesis]. Jawaharlal Nehru Technological University, Hyderabad; 2012. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/19041

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

27. Singh, Priyanka. A novel Drosophila model of pentylenetetrazole withdrawal induced brain plasticity: behavioral and functional genomic characterization.

Degree: 2009, University of Pune

URL: http://shodhganga.inflibnet.ac.in/handle/10603/2512

►

Systems biology is an emerging field that promises understanding of the entirety of processes that happen in a biological system, a long awaited objective of… (more)

Subjects/Keywords: Biotechnology; Drug dosage; Bioinformatics; Brain plasticity

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APA (6^th Edition):

Singh, P. (2009). A novel Drosophila model of pentylenetetrazole withdrawal induced brain plasticity: behavioral and functional genomic characterization. (Thesis). University of Pune. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/2512

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Singh, Priyanka. “A novel Drosophila model of pentylenetetrazole withdrawal induced brain plasticity: behavioral and functional genomic characterization.” 2009. Thesis, University of Pune. Accessed February 17, 2020. http://shodhganga.inflibnet.ac.in/handle/10603/2512.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Singh, Priyanka. “A novel Drosophila model of pentylenetetrazole withdrawal induced brain plasticity: behavioral and functional genomic characterization.” 2009. Web. 17 Feb 2020.

Vancouver:

Singh P. A novel Drosophila model of pentylenetetrazole withdrawal induced brain plasticity: behavioral and functional genomic characterization. [Internet] [Thesis]. University of Pune; 2009. [cited 2020 Feb 17]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/2512.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Singh P. A novel Drosophila model of pentylenetetrazole withdrawal induced brain plasticity: behavioral and functional genomic characterization. [Thesis]. University of Pune; 2009. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/2512

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

28. Hemrajbhai,Bariya Shital. Studies in modulation of venlafaxine hydrochloride release from solid dosage forms;.

Degree: Pharmaceutics and Pharmaceutical Technology, 2015, Gujarat University

URL: http://shodhganga.inflibnet.ac.in/handle/10603/48529

Abstract Not Available

Data not available

Advisors/Committee Members: Gohel,Mukesh.

Subjects/Keywords: Dosage; Hydrochloride; Venlafaxine

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APA (6^th Edition):

Shital, H. (2015). Studies in modulation of venlafaxine hydrochloride release from solid dosage forms;. (Thesis). Gujarat University. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/48529

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Shital, Hemrajbhai,Bariya. “Studies in modulation of venlafaxine hydrochloride release from solid dosage forms;.” 2015. Thesis, Gujarat University. Accessed February 17, 2020. http://shodhganga.inflibnet.ac.in/handle/10603/48529.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Shital, Hemrajbhai,Bariya. “Studies in modulation of venlafaxine hydrochloride release from solid dosage forms;.” 2015. Web. 17 Feb 2020.

Vancouver:

Shital H. Studies in modulation of venlafaxine hydrochloride release from solid dosage forms;. [Internet] [Thesis]. Gujarat University; 2015. [cited 2020 Feb 17]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/48529.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Shital H. Studies in modulation of venlafaxine hydrochloride release from solid dosage forms;. [Thesis]. Gujarat University; 2015. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/48529

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Johannesburg

29. Van der Merwe, Dalena. Medikasiehantering deur die verpleegkundige in 'n intensiewe sorgeenheid.

Degree: 2014, University of Johannesburg

URL: http://hdl.handle.net/10210/11847

►

M.Cur. (General Intensive Nursing)

In South Africa, where the nurse is seen as an independent practitioner, she must take continuously accountability and responsibility for her… (more)

▼

M.Cur. (General Intensive Nursing)

In South Africa, where the nurse is seen as an independent practitioner, she must take continuously accountability and responsibility for her actions. Only she can decide whether she is legally able, or knowledgeable and competent enough to accept a prescription or direction from a doctor. Once she has indicated acceptance, she has made an independent decision and accepts full responsibility and accountability for her decisions and actions. Accountability means that the nurse must be able to give a reason for her actions and or omissions. It is very important that she has enough knowledge of the effects, side-effects, indications and contra-indications of the medications that are prescribed by the doctor before she administers it. Knowledge of medications and the Nursing Act with related regulations that directs her practice, are very important to the nurse to ensure a high standard of nursing care. The nurse working in an intensive care unit must often make decisions in a crisis situation in connection with her legal accountability. So much more in the private sector where the intensive care nurse must .often rely on her own judgement and knowledge because a doctor is not always available. Two questions evolving from this is what is the nurse's responsibility with in the legal framework of medication administration in a intensive care unit and do nurses have enough knowledge of selected medications? These two questions have been answered by evaluation of the doctor's prescriptions and nursing actions, with the help of prelisted control lists and a questionnaire The results of the study showed that the doctor's prescriptions were not legally correct and nurse's actions and knowledge of the selected medications were not up to the expected standard in the chosen unit. Two recommendations evolving from this study are that inservice training to increase knowledge of medications that are frequently used in the unit should be presented monthly and that more time must be spent on pharmacology during the training of the intensive care nurse.

Subjects/Keywords: Intensive care nursing; Drugs - South Africa - Dosage

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APA (6^th Edition):

Van der Merwe, D. (2014). Medikasiehantering deur die verpleegkundige in 'n intensiewe sorgeenheid. (Thesis). University of Johannesburg. Retrieved from http://hdl.handle.net/10210/11847

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Van der Merwe, Dalena. “Medikasiehantering deur die verpleegkundige in 'n intensiewe sorgeenheid.” 2014. Thesis, University of Johannesburg. Accessed February 17, 2020. http://hdl.handle.net/10210/11847.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Van der Merwe, Dalena. “Medikasiehantering deur die verpleegkundige in 'n intensiewe sorgeenheid.” 2014. Web. 17 Feb 2020.

Vancouver:

Van der Merwe D. Medikasiehantering deur die verpleegkundige in 'n intensiewe sorgeenheid. [Internet] [Thesis]. University of Johannesburg; 2014. [cited 2020 Feb 17]. Available from: http://hdl.handle.net/10210/11847.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Van der Merwe D. Medikasiehantering deur die verpleegkundige in 'n intensiewe sorgeenheid. [Thesis]. University of Johannesburg; 2014. Available from: http://hdl.handle.net/10210/11847

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Pretoria

30. Massinga, Pedro Horacio. Gel-based solid dosage form for pesticide delivery.

Degree: Chemistry, 2010, University of Pretoria

URL: http://hdl.handle.net/2263/23498

► The aim of this research was to develop a solid dosage form containing 1.5 g of the pesticide cypermethrin. The dosage should be stable in… (more)

▼ The aim of this research was to develop a solid dosage form containing 1.5 g of the pesticide cypermethrin. The dosage should be stable in a tropical climate. In addition, it is to disintegrate and disperse in 10 L of tap water within 3 minutes. Such dissolution should yield a 150 ppm dispersion of cypermethrin, stable for at least one week. This provides for a dip dispersion to treat ticks and fly infestation on livestock. A new solid dosage was formulated as the scope of this research. It is a gel-based solid dosage form. Polymer electrolyte ASP4 - a copolymer of methacrylic acid, ethyl acrylate and diethyl maleate, was used to produce the gel. Preliminary tests revealed that ASP4- based gel, on its own, failed to meet the required dissolution time of 3 minutes. Strong entanglements of ASP4 chains impeded rapid dissolution. These strong entanglements occurred owing to the use of a high concentration of ASP4. Reducing the concentration of ASP4 yielded a solution of high viscosity instead of a gel. It was therefore decided to Gel-based solid dosage form for pesticide delivery use a superabsorbent (Product Z1069) in conjunction with ASP4 to produce the gel. Product Z1069 is a cross-linked sodium polyacrylate. Before producing the gel, a 1:1.5 by mass oil/water (O/W) emulsion was prepared using the phase-inversion route. The water (W) phase comprised 85.9% distilled water, 3.9% ASP4 at 20% dispersion, 8.6% sodium carbonate (0.5 M) and 1.6% Emulsogen EL. All concentrations are indicated in mass %. The oil (O) phase consisted of 76.9% cypermethrin, 19.3% Solvesso S200 and 3.8% Phenyl Sulphonate CA, also by mass. This emulsion was gelled by adding the superabsorbent Product Z1069 (ca. 37.5% by mass relative to the W phase of the emulsion). The superabsorbent strongly absorbed water, depleting it from the emulsion. This resulted in an increase of the effective concentration of ASP4 in the water phase of the emulsion. This increase of the polymer electrolyte concentration brought about a gel-like state corresponding to the desired solid dosage form. Rheometry confirmed that the dosage form maintained a solid gel-like consistency at 50°C. The dosage contained 24.6% m/m cypermethrin. Thus, the required dosage of 1.5 g was achieved in pellets weighing ca. 6.1 g. Such pellets rapidly disintegrated with mild stirring in 10 L of tap water. Complete pellet disintegration and active dispersion occurred within 2.5 minutes at ambient temperature (25 ± 2°C). Advisors/Committee Members: Focke, Walter Wilhelm (advisor).

Subjects/Keywords: Cypermethrin; Solid dosage form; Gel; Emulsion; UCTD

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APA (6^th Edition):

Massinga, P. H. (2010). Gel-based solid dosage form for pesticide delivery. (Masters Thesis). University of Pretoria. Retrieved from http://hdl.handle.net/2263/23498

Chicago Manual of Style (16^th Edition):

Massinga, Pedro Horacio. “Gel-based solid dosage form for pesticide delivery.” 2010. Masters Thesis, University of Pretoria. Accessed February 17, 2020. http://hdl.handle.net/2263/23498.

MLA Handbook (7^th Edition):

Massinga, Pedro Horacio. “Gel-based solid dosage form for pesticide delivery.” 2010. Web. 17 Feb 2020.

Vancouver:

Massinga PH. Gel-based solid dosage form for pesticide delivery. [Internet] [Masters thesis]. University of Pretoria; 2010. [cited 2020 Feb 17]. Available from: http://hdl.handle.net/2263/23498.

Council of Science Editors:

Massinga PH. Gel-based solid dosage form for pesticide delivery. [Masters Thesis]. University of Pretoria; 2010. Available from: http://hdl.handle.net/2263/23498

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Open Access Theses and Dissertations