Advanced search options

Advanced Search Options 🞨

Browse by author name (“Author name starts with…”).

Find ETDs with:

in
/  
in
/  
in
/  
in

Written in Published in Earliest date Latest date

Sorted by

Results per page:

You searched for subject:(Dna Binding Clearage). One record found.

Search Limiters

Last 2 Years | English Only

No search limiters apply to these results.

▼ Search Limiters

1. Jayaseelan, P. Synthesis, characterization, redox, dna binding, cleavage and anti-microbial activities of novel schiff base binuclear metal complexes; -.

Degree: Chemistry, 2011, Periyar University

A novel binucleating Schiff base ligands have been prepared by the condensation between 3,3 diaminobenzidine with phthalaldehyde monoxime, 2, 3 butanedione monoxime and O-hydroxyacetophenone. The Schiff base ligands and metal complexes were characterized by elemental analysis, UV, IR, 1H NMR, 13C NMR, conductivity measurements, cyclic voltammetry, thermal studies, EPR and magnetic studies. In molar conductance studies, most of the complexes showed non-electrolytic in nature and only few of the complexes were electrolytic in nature. The binucleating ligand can coordinate with two metal ions to form binuclear complexes and the complexes exhibit octahedral and square planar arrangements. In electrochemical studies, the resulting cyclic voltammograms indicates that the metal(II) complexes followed quasi-reversible reactions with one electron transfer. The TGA curves show that the decomposition takes place in three steps for metal complexes. The synthesized ligand, in comparison to their metal complexes also were screened for its antimicrobial activity against Staphylococcus aureus and Streptococcus pyogenes as Gram-positive bacteria and Escherichia coli and Klebsiella pneumoniae as Gram-negative and the fungi Fusarium oxysporum, Aspergillus fumigatus and Aspergillus flavus. In antimicrobial activity, all complexes are showed good antimicrobial activity than ligands. The DNA binding properties of copper(II) metal complexes have been investigated by electronic absorption spectroscopy, viscosity measurements and cyclic voltammetry. Results suggest that the copper(II) complexes bind to DNA via an intercalation binding mode. The nucleolytic cleavage activities of the ligands and their complexes were assayed by using gel electrophoresis in the presence of H2O2. Metal(II) binuclear complexes are showed significant cleavages.

Publication p.248-251

Advisors/Committee Members: Rajavel, R.

Subjects/Keywords: Novel Sch; Synthesis; Redoxn; Dna Binding Clearage; Anti - Microbial Activities

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Jayaseelan, P. (2011). Synthesis, characterization, redox, dna binding, cleavage and anti-microbial activities of novel schiff base binuclear metal complexes; -. (Thesis). Periyar University. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/17419

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Jayaseelan, P. “Synthesis, characterization, redox, dna binding, cleavage and anti-microbial activities of novel schiff base binuclear metal complexes; -.” 2011. Thesis, Periyar University. Accessed October 16, 2019. http://shodhganga.inflibnet.ac.in/handle/10603/17419.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Jayaseelan, P. “Synthesis, characterization, redox, dna binding, cleavage and anti-microbial activities of novel schiff base binuclear metal complexes; -.” 2011. Web. 16 Oct 2019.

Vancouver:

Jayaseelan P. Synthesis, characterization, redox, dna binding, cleavage and anti-microbial activities of novel schiff base binuclear metal complexes; -. [Internet] [Thesis]. Periyar University; 2011. [cited 2019 Oct 16]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/17419.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Jayaseelan P. Synthesis, characterization, redox, dna binding, cleavage and anti-microbial activities of novel schiff base binuclear metal complexes; -. [Thesis]. Periyar University; 2011. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/17419

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

.