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You searched for subject:(Dissolving microneedle). Showing records 1 – 2 of 2 total matches.

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NSYSU

1. Liao, Jing-fong. Flexible and Rapidly-Dissolvable Microneedle Patches for Transdermal Delivery and Stability Enhancement of DNA Vaccine.

Degree: Master, Institute of Medical Science and Technology, 2016, NSYSU

This study developed a flexible and rapidly-dissolvable microneedle (MN) patch for transdermal delivery and stability enhancement of DNA vaccine. The MN patch is made by polyvinyl alcohol (PVA) with the properties of rapid dissolution, biocompatibility and film-forming. Besides, the vaccine encapsulated in MN would be rapidly released after insertion of the MN patch to the skin. We were able to encapsulate 22.4 μg of PCV2 plasmid DNA vaccine in MNs per patch with a loading rate of 87.8 wt % when casting the PCV2 plasmid DNA vaccination the PDMS mode surface. We also done the stability study, the activity of vaccine encapsulated in MNs can be maintained exceed 111 days without any damage at 37 â of storage. The ex vivo study demonstrated that the MNs have excellent mechanical strength to puncture the stratum corneum and needles can be dissolved within 10 minutes to release the vaccine in epidermis then the hole can be quickly healed within 40 minutes to avoid the infection risk. The Animals studies showed that the induced antibody titers via MN patch administration were about 10-time higher than intramuscular (IM) administration after 3 weeks of vaccination. The results confirmed that the MNs can induce high antibody concentration in body to induce the strongest immune responses after immunization. Advisors/Committee Members: Hung-Wei Yang (committee member), Jin-Ching Lee (chair), Chen-Chi M. Ma (chair).

Subjects/Keywords: Transcutaneous immunization; Dissolving microneedle; DNA vaccine; Flexible patches; Polyvinyl alcohol

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Liao, J. (2016). Flexible and Rapidly-Dissolvable Microneedle Patches for Transdermal Delivery and Stability Enhancement of DNA Vaccine. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0529116-155910

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Liao, Jing-fong. “Flexible and Rapidly-Dissolvable Microneedle Patches for Transdermal Delivery and Stability Enhancement of DNA Vaccine.” 2016. Thesis, NSYSU. Accessed January 15, 2021. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0529116-155910.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Liao, Jing-fong. “Flexible and Rapidly-Dissolvable Microneedle Patches for Transdermal Delivery and Stability Enhancement of DNA Vaccine.” 2016. Web. 15 Jan 2021.

Vancouver:

Liao J. Flexible and Rapidly-Dissolvable Microneedle Patches for Transdermal Delivery and Stability Enhancement of DNA Vaccine. [Internet] [Thesis]. NSYSU; 2016. [cited 2021 Jan 15]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0529116-155910.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Liao J. Flexible and Rapidly-Dissolvable Microneedle Patches for Transdermal Delivery and Stability Enhancement of DNA Vaccine. [Thesis]. NSYSU; 2016. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0529116-155910

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

2. KOH KAI JUN. FABRICATION OF DISSOLVING MICRONEEDLES FOR MRNA DELIVERY.

Degree: 2017, National University of Singapore

Subjects/Keywords: mRNA; dissolving; microneedle; PVP; transcutaneous; luciferase

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

JUN, K. K. (2017). FABRICATION OF DISSOLVING MICRONEEDLES FOR MRNA DELIVERY. (Thesis). National University of Singapore. Retrieved from http://scholarbank.nus.edu.sg/handle/10635/138443

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

JUN, KOH KAI. “FABRICATION OF DISSOLVING MICRONEEDLES FOR MRNA DELIVERY.” 2017. Thesis, National University of Singapore. Accessed January 15, 2021. http://scholarbank.nus.edu.sg/handle/10635/138443.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

JUN, KOH KAI. “FABRICATION OF DISSOLVING MICRONEEDLES FOR MRNA DELIVERY.” 2017. Web. 15 Jan 2021.

Vancouver:

JUN KK. FABRICATION OF DISSOLVING MICRONEEDLES FOR MRNA DELIVERY. [Internet] [Thesis]. National University of Singapore; 2017. [cited 2021 Jan 15]. Available from: http://scholarbank.nus.edu.sg/handle/10635/138443.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

JUN KK. FABRICATION OF DISSOLVING MICRONEEDLES FOR MRNA DELIVERY. [Thesis]. National University of Singapore; 2017. Available from: http://scholarbank.nus.edu.sg/handle/10635/138443

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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