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You searched for subject:(Dietary base). Showing records 1 – 2 of 2 total matches.

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University of New South Wales

1. Kozan, Pinar. The effect of buffering a high acid load meal with sodium bicarbonate on postprandial glucose metabolism in humans.

Degree: St Vincent's Clinical School, 2018, University of New South Wales

Background: High dietary acid load relates to increased risk of type 2 diabetes in epidemiological studies. We aimed to investigate whether buffering a high acid load meal with an alkalising treatment changes post meal glucose metabolism. Methods: Non-diabetic participants (n=32) were randomized to receive either NaHCO3 1680mg or placebo, followed by a high acid load meal in a double-blind placebo-controlled crossover (1-4 weeks apart) study. Thirty (20 males) participants completed the study. Venous blood pH, serum bicarbonate, blood glucose, serum insulin, C-peptide, non-esterified fatty acid (NEFA), and plasma glucagon-like peptide-1 (GLP-1) concentrations were measured at baseline (fasting) and at 15-30min intervals for 3h post meal. Results: The treatment was well tolerated. Venous blood pH declined in the first 15min post meal with the placebo (p=0.001), but not with NaHCO3 (p=0.86) and remained lower with the placebo for 3h (pinteraction=0.04). The iAUC of pH was significantly higher following the NaHCO3 treatment versus the placebo (p=0.02). However, postprandial glucose, insulin, C-peptide, NEFA and GLP-1 were not different between treatments (pinteraction≄0.07). Conclusions: An alkalising medication administered pre-meal has no acute effect on glycaemia and insulin response in healthy individuals. Long-term interventions in at-risk populations are necessary to investigate the effect of sustained alkalisation on glucose metabolism. Advisors/Committee Members: Greenfield , Jerry, Garvan Institute of Medical Research, Faculty of Medicine, UNSW, Samocha-Bonet, Dorit, Garvan Institute of Medical Research, Faculty of Medicine, UNSW.

Subjects/Keywords: acid-base homeostasis; alkaline diet; dietary acid load; type 2 diabetes; sodium bicarbonate; postprandial glycaemia

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APA (6th Edition):

Kozan, P. (2018). The effect of buffering a high acid load meal with sodium bicarbonate on postprandial glucose metabolism in humans. (Masters Thesis). University of New South Wales. Retrieved from http://handle.unsw.edu.au/1959.4/59592 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:49042/SOURCE02?view=true

Chicago Manual of Style (16th Edition):

Kozan, Pinar. “The effect of buffering a high acid load meal with sodium bicarbonate on postprandial glucose metabolism in humans.” 2018. Masters Thesis, University of New South Wales. Accessed February 27, 2021. http://handle.unsw.edu.au/1959.4/59592 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:49042/SOURCE02?view=true.

MLA Handbook (7th Edition):

Kozan, Pinar. “The effect of buffering a high acid load meal with sodium bicarbonate on postprandial glucose metabolism in humans.” 2018. Web. 27 Feb 2021.

Vancouver:

Kozan P. The effect of buffering a high acid load meal with sodium bicarbonate on postprandial glucose metabolism in humans. [Internet] [Masters thesis]. University of New South Wales; 2018. [cited 2021 Feb 27]. Available from: http://handle.unsw.edu.au/1959.4/59592 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:49042/SOURCE02?view=true.

Council of Science Editors:

Kozan P. The effect of buffering a high acid load meal with sodium bicarbonate on postprandial glucose metabolism in humans. [Masters Thesis]. University of New South Wales; 2018. Available from: http://handle.unsw.edu.au/1959.4/59592 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:49042/SOURCE02?view=true

2. Watts, Sarah Miriam. Diet and indices of bone breakdown and acid production in bed rest subjects.

Degree: MS, Nutrition and Food Sciences, 2012, Texas Woman's University

Diet and acid-base balance can affect bone loss during simulated weightlessness. The present study evaluates the effects of acid and base components of diet on bone resorption markers before, during, and after 60-90 days of bed rest at -6° head-down tilt position. A total of eleven subjects (8M, 3F; age 26-44 y) participated in the present study. Urine samples from the subjects were analyzed for a relationship between dietary patterns and markers of bone metabolism. This study examines two procedures for estimating acid production in the body by comparing urinary net acid excretion (NAEindirect ) and by measuring the animal protein to potassium ratio, as estimated from dietary intake. It is hypothesized that both estimations would have significant correlations between markers of bone breakdown NTX (N-telopeptide) and PYD (pyridinoline). Results confirmed that bone resorption increased during bed rest as indicated by the collagen crosslinks NTX and PYD. In addition, significant correlations were recorded between NAEindirect and NTX (p<0.01), and PYD (p<0.01) during bed rest. However, the ratio of animal protein to potassium intake was not significantly correlated with NTX or PYD, suggesting further research on this method of approximating acid load is necessary. Advisors/Committee Members: Juma, Shanil (Committee Chair), Vijayagopal, Parakat (committee member).

Subjects/Keywords: Health and environmental sciences; Aging; Bone loss; Weightlessness; Bed rest; Bone; Bone resorption; Bone markers; Collagen crosslinks; NTX (N-telopeptide); PYD (pyridinoline); Acid-base homeostasis; Dietary acid; Dietary base; Urinary net acid excretion (NAE); Animal to potassium ratio

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Watts, S. M. (2012). Diet and indices of bone breakdown and acid production in bed rest subjects. (Masters Thesis). Texas Woman's University. Retrieved from https://twu-ir.tdl.org/handle/11274/10477

Chicago Manual of Style (16th Edition):

Watts, Sarah Miriam. “Diet and indices of bone breakdown and acid production in bed rest subjects.” 2012. Masters Thesis, Texas Woman's University. Accessed February 27, 2021. https://twu-ir.tdl.org/handle/11274/10477.

MLA Handbook (7th Edition):

Watts, Sarah Miriam. “Diet and indices of bone breakdown and acid production in bed rest subjects.” 2012. Web. 27 Feb 2021.

Vancouver:

Watts SM. Diet and indices of bone breakdown and acid production in bed rest subjects. [Internet] [Masters thesis]. Texas Woman's University; 2012. [cited 2021 Feb 27]. Available from: https://twu-ir.tdl.org/handle/11274/10477.

Council of Science Editors:

Watts SM. Diet and indices of bone breakdown and acid production in bed rest subjects. [Masters Thesis]. Texas Woman's University; 2012. Available from: https://twu-ir.tdl.org/handle/11274/10477

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