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Freie Universität Berlin
1.
Goebbels, Michael.
Investigation for the practical use of anionic rations to prevent hypocalcemia
in dairy herds.
Degree: 2006, Freie Universität Berlin
URL: https://refubium.fu-berlin.de/handle/fub188/12567 
► The aim of this study was to find a solution how to valuate the effect of anionic rations with herd datas and to make the…
(more)
▼ The aim of this study was to find a solution how to valuate the effect of
anionic rations with herd datas and to make the use of anions safer. The first
part of the study shows the examinations about the practical use of the
measurement of urine ph to valuate the effects of anions on the acid-
base
status. For that purpose, samples of urine were taken for eight weeks from the
two weeks prepartum cows of two different farms. The ph was measured with an
electrical ph-meter in the cowshed and with ph-stripes directly after the
winning. Apart from that, the urine was frozen and after defrosting measured
with an electrical ph-meter in the lab. The measurement of the ph by ph-
stripes showed nearly the similar results than the measurement of the urine ph
by electrical ph-meter directly after the winning. After defrosting the urine,
the results of the urine ph were slightly increased. Within the scope of herd
management fifty farms were visited and some of them more than one time. Blood
and urine samples were taken from close up dry cows and recently calved cows.
The ration of the close up dry cows was analysed. Ten single samples of blood
and urine were necessary to produce a pool sample. The values of the pool
samples of urine ph, net acid-
base excretion and urine calcium excretion were
compared with the mean values of the single samples. There were high
correlations between the pool and the mean values for each of the parameters.
Because of that, the pool and the mean values have nearly the same content of
information. The analyses of the rations from 2002 to 2004 contain the dcad
and the amount of potassium, sodium, chloride and sulphur. Herds with and
without anionic rations were compared. The analysis of the feed of herds with
anionic rations showed a lower dcad and a higher amount of sulphur in all of
the three years. But the recommendations of the NRC were not achieved. That is
an indication that not enough anionic salts were used refer to the rations
content. To examine the influence of more factors of the ration on the effect
of the anions the urine ph, the net acid-
base excretion and the urine calcium
excretion were compared with the parameters of the rations. The effect of
reducing the dcad and the amount of potassium as well as the effect of
increasing the amount of calcium and sulphur in the ration is a mild acidosis
and an increased urine calcium excretion. These are the effects of the anions.
Within feeding anions there should be a shift of the major elements. This
leads to a decreased dcad and to the metabolic effects as described. The same
effects on the acid-
base status and the urine calcium excretion were observed
by feeding an increased amount of starch and a decreased amount of crude
fibre. This could simulate the effect of anionic rations. The parameters of
the energy concentration in the rations have a slight correlation with the
parameters of the acid-
base status. At low amounts of energy there is an
acidotic stress of the animals. This has to be avoided when farmers use
anionic rations because it…
Advisors/Committee Members: n (gender), Univ.-Prof. Dr. R. Staufenbiel (firstReferee), Prof. Dr. H. Tönhardt (furtherReferee), Univ.-Prof. Dr. R. Fries (furtherReferee).
Subjects/Keywords: dairy cow; hypocalcemic parturient paresis; dietary cation-anion balance; acid-base status; anionic salts; major elements; metabolic profile; herd management; 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche
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APA (6th Edition):
Goebbels, M. (2006). Investigation for the practical use of anionic rations to prevent hypocalcemia
in dairy herds. (Thesis). Freie Universität Berlin. Retrieved from https://refubium.fu-berlin.de/handle/fub188/12567
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Goebbels, Michael. “Investigation for the practical use of anionic rations to prevent hypocalcemia
in dairy herds.” 2006. Thesis, Freie Universität Berlin. Accessed January 16, 2021.
https://refubium.fu-berlin.de/handle/fub188/12567.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Goebbels, Michael. “Investigation for the practical use of anionic rations to prevent hypocalcemia
in dairy herds.” 2006. Web. 16 Jan 2021.
Vancouver:
Goebbels M. Investigation for the practical use of anionic rations to prevent hypocalcemia
in dairy herds. [Internet] [Thesis]. Freie Universität Berlin; 2006. [cited 2021 Jan 16].
Available from: https://refubium.fu-berlin.de/handle/fub188/12567.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Goebbels M. Investigation for the practical use of anionic rations to prevent hypocalcemia
in dairy herds. [Thesis]. Freie Universität Berlin; 2006. Available from: https://refubium.fu-berlin.de/handle/fub188/12567
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of New South Wales
2.
Kozan, Pinar.
The effect of buffering a high acid load meal with sodium bicarbonate on postprandial glucose metabolism in humans.
Degree: St Vincent's Clinical School, 2018, University of New South Wales
URL: http://handle.unsw.edu.au/1959.4/59592
;
https://unsworks.unsw.edu.au/fapi/datastream/unsworks:49042/SOURCE02?view=true
► Background: High dietary acid load relates to increased risk of type 2 diabetes in epidemiological studies. We aimed to investigate whether buffering a high acid…
(more)
▼ Background: High
dietary acid load relates to increased risk of type 2 diabetes in epidemiological studies. We aimed to investigate whether buffering a high acid load meal with an alkalising treatment changes post meal glucose metabolism. Methods: Non-diabetic participants (n=32) were randomized to receive either NaHCO3 1680mg or placebo, followed by a high acid load meal in a double-blind placebo-controlled crossover (1-4 weeks apart) study. Thirty (20 males) participants completed the study. Venous blood pH, serum bicarbonate, blood glucose, serum insulin, C-peptide, non-esterified fatty acid (NEFA), and plasma glucagon-like peptide-1 (GLP-1) concentrations were measured at baseline (fasting) and at 15-30min intervals for 3h post meal. Results: The treatment was well tolerated. Venous blood pH declined in the first 15min post meal with the placebo (p=0.001), but not with NaHCO3 (p=0.86) and remained lower with the placebo for 3h (pinteraction=0.04). The iAUC of pH was significantly higher following the NaHCO3 treatment versus the placebo (p=0.02). However, postprandial glucose, insulin, C-peptide, NEFA and GLP-1 were not different between treatments (pinteraction≥0.07). Conclusions: An alkalising medication administered pre-meal has no acute effect on glycaemia and insulin response in healthy individuals. Long-term interventions in at-risk populations are necessary to investigate the effect of sustained alkalisation on glucose metabolism.
Advisors/Committee Members: Greenfield , Jerry, Garvan Institute of Medical Research, Faculty of Medicine, UNSW, Samocha-Bonet, Dorit, Garvan Institute of Medical Research, Faculty of Medicine, UNSW.
Subjects/Keywords: acid-base homeostasis; alkaline diet; dietary acid load; type 2 diabetes; sodium bicarbonate; postprandial glycaemia
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APA ·
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MLA ·
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CSE |
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Manager
APA (6th Edition):
Kozan, P. (2018). The effect of buffering a high acid load meal with sodium bicarbonate on postprandial glucose metabolism in humans. (Masters Thesis). University of New South Wales. Retrieved from http://handle.unsw.edu.au/1959.4/59592 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:49042/SOURCE02?view=true
Chicago Manual of Style (16th Edition):
Kozan, Pinar. “The effect of buffering a high acid load meal with sodium bicarbonate on postprandial glucose metabolism in humans.” 2018. Masters Thesis, University of New South Wales. Accessed January 16, 2021.
http://handle.unsw.edu.au/1959.4/59592 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:49042/SOURCE02?view=true.
MLA Handbook (7th Edition):
Kozan, Pinar. “The effect of buffering a high acid load meal with sodium bicarbonate on postprandial glucose metabolism in humans.” 2018. Web. 16 Jan 2021.
Vancouver:
Kozan P. The effect of buffering a high acid load meal with sodium bicarbonate on postprandial glucose metabolism in humans. [Internet] [Masters thesis]. University of New South Wales; 2018. [cited 2021 Jan 16].
Available from: http://handle.unsw.edu.au/1959.4/59592 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:49042/SOURCE02?view=true.
Council of Science Editors:
Kozan P. The effect of buffering a high acid load meal with sodium bicarbonate on postprandial glucose metabolism in humans. [Masters Thesis]. University of New South Wales; 2018. Available from: http://handle.unsw.edu.au/1959.4/59592 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:49042/SOURCE02?view=true
Freie Universität Berlin
3.
Montag, Nicole.
Experimental investigation of the effects of different anionic salts to the
acid-base balance of dairy cows.
Degree: 2005, Freie Universität Berlin
URL: https://refubium.fu-berlin.de/handle/fub188/11529
► The aim of this study was to get further information about the influence of different factors to the effect of anionic rations, to optimize the…
(more)
▼ The aim of this study was to get further information about the influence of
different factors to the effect of anionic rations, to optimize the use of
anionic salts in the prevention of milk fever of dairy cows. These factors are
the influence of a prolonged administration of anions, of different energy and
calcium supply, the effects of the sodium-potassium relation, the maximal
tolerated dose of calcium sulfate as well as the investigation about the
application of the daily dose of calcium chloride and calcium sulfate once a
day.
From february 2003 to march 2004 the investigations were performed on cows
with rumen fistula. During the trials the animals got the acid salts calcium
chloride and calcium sulfate through the rumen fistula twice a day at the
feedings (except for the trial about the once a day application and the trial
with sodium- and potassium bicarbonate). Several times a week blood and urine
samples were taken to determine the blood gas analysis (ph, be, CO2, O2) as
well as the net acid-
base excretion. For each trial the feed was analysed and
the dcad of the ration was measured. In all 1401 blood and urine samples have
been taken and examined.
The prolonged administration of anions showed, that the entire effect of the
anionic salts is completely developed after 3 7 days. A significant
metabolic acidosis set in. The values of ph, be and bicarbonate of the blood
decreased. In the urine the effect of the acidosis was observed as well. There
was a significant decrease in ph and nsba. Because of the fact, that the
complete effects are developed within 3 7 days, and because of the risk of
strong disturbances of the acid-
base equilibrium, the use of the acid salts
should last 7 days at least, but not longer than 14 days. The results of the
investigation about the different energy supply showed, that the concentration
of energy should be sufficient to avoid a further increase of the acidosis by
the metabolic products, which result from the degradation of fatty and amino
acid at catabolism. The degree of the calcium supply had no significant
influence of the impact of the anionic salts relating to the acid-
base status.
Never the less, when feeding acid salts, it is very important to supply
calcium in sufficient amount (120 180g/d), because of the strong renal
calcium excretion. The investigation of the impact of sodium and potassium
showed, that cations can counteract and compensate the effects of the anions
and with it the mechanism of the prophylaxis of milk fever.
The application of anions and cations in equivalent amounts at the same time
had no effect of the acid-
base-balance. The exclusive use of sodium- and
potassium bicarbonate did not show the expected alkaline effects. The
investigation of the maximal tolerated dose of calcium sulfate showed, that
the cows developed a strong metabolic acidosis after one week of application
of 3 equivalents of calcium sulfate. Because of that, the dose of 3
equivalents should not be exceeded. It is better to think of 2,5 equivalents
as upper limit. The…
Advisors/Committee Members: n (gender), Univ.-Prof. Dr. R. Staufenbiel (firstReferee), Prof. Dr. H. Tönhardt (furtherReferee), Univ.-Prof. Dr. G. Hildebrandt (furtherReferee).
Subjects/Keywords: dairy cow; hypocalcemic parturient paresis; dietary cation-anion balance; acid-base status; anionic salts; calcium chloride; calcium sulfate; 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche
Record Details
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Record Details
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Montag, N. (2005). Experimental investigation of the effects of different anionic salts to the
acid-base balance of dairy cows. (Thesis). Freie Universität Berlin. Retrieved from https://refubium.fu-berlin.de/handle/fub188/11529
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Montag, Nicole. “Experimental investigation of the effects of different anionic salts to the
acid-base balance of dairy cows.” 2005. Thesis, Freie Universität Berlin. Accessed January 16, 2021.
https://refubium.fu-berlin.de/handle/fub188/11529.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Montag, Nicole. “Experimental investigation of the effects of different anionic salts to the
acid-base balance of dairy cows.” 2005. Web. 16 Jan 2021.
Vancouver:
Montag N. Experimental investigation of the effects of different anionic salts to the
acid-base balance of dairy cows. [Internet] [Thesis]. Freie Universität Berlin; 2005. [cited 2021 Jan 16].
Available from: https://refubium.fu-berlin.de/handle/fub188/11529.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Montag N. Experimental investigation of the effects of different anionic salts to the
acid-base balance of dairy cows. [Thesis]. Freie Universität Berlin; 2005. Available from: https://refubium.fu-berlin.de/handle/fub188/11529
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
4.
Watts, Sarah Miriam.
Diet and indices of bone breakdown and acid production in bed rest subjects.
Degree: MS, Nutrition and Food Sciences, 2012, Texas Woman's University
URL: https://twu-ir.tdl.org/handle/11274/10477
► Diet and acid-base balance can affect bone loss during simulated weightlessness. The present study evaluates the effects of acid and base components of diet on…
(more)
▼ Diet and acid-
base balance can affect bone loss during simulated weightlessness. The present study evaluates the effects of acid and
base components of diet on bone resorption markers before, during, and after 60-90 days of bed rest at -6° head-down tilt position. A total of eleven subjects (8M, 3F; age 26-44 y) participated in the present study. Urine samples from the subjects were analyzed for a relationship between
dietary patterns and markers of bone metabolism. This study examines two procedures for estimating acid production in the body by comparing urinary net acid excretion (NAEindirect ) and by measuring the animal protein to potassium ratio, as estimated from
dietary intake. It is hypothesized that both estimations would have significant correlations between markers of bone breakdown NTX (N-telopeptide) and PYD (pyridinoline). Results confirmed that bone resorption increased during bed rest as indicated by the collagen crosslinks NTX and PYD. In addition, significant correlations were recorded between NAEindirect and NTX (p<0.01), and PYD (p<0.01) during bed rest. However, the ratio of animal protein to potassium intake was not significantly correlated with NTX or PYD, suggesting further research on this method of approximating acid load is necessary.
Advisors/Committee Members: Juma, Shanil (Committee Chair), Vijayagopal, Parakat (committee member).
Subjects/Keywords: Health and environmental sciences; Aging; Bone loss; Weightlessness; Bed rest; Bone; Bone resorption; Bone markers; Collagen crosslinks; NTX (N-telopeptide); PYD (pyridinoline); Acid-base homeostasis; Dietary acid; Dietary base; Urinary net acid excretion (NAE); Animal to potassium ratio
Record Details
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Record Details
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Watts, S. M. (2012). Diet and indices of bone breakdown and acid production in bed rest subjects. (Masters Thesis). Texas Woman's University. Retrieved from https://twu-ir.tdl.org/handle/11274/10477
Chicago Manual of Style (16th Edition):
Watts, Sarah Miriam. “Diet and indices of bone breakdown and acid production in bed rest subjects.” 2012. Masters Thesis, Texas Woman's University. Accessed January 16, 2021.
https://twu-ir.tdl.org/handle/11274/10477.
MLA Handbook (7th Edition):
Watts, Sarah Miriam. “Diet and indices of bone breakdown and acid production in bed rest subjects.” 2012. Web. 16 Jan 2021.
Vancouver:
Watts SM. Diet and indices of bone breakdown and acid production in bed rest subjects. [Internet] [Masters thesis]. Texas Woman's University; 2012. [cited 2021 Jan 16].
Available from: https://twu-ir.tdl.org/handle/11274/10477.
Council of Science Editors:
Watts SM. Diet and indices of bone breakdown and acid production in bed rest subjects. [Masters Thesis]. Texas Woman's University; 2012. Available from: https://twu-ir.tdl.org/handle/11274/10477
. 
Open Access Theses and Dissertations