subject:(DNP)

Texas A&M University

1. Chen, Hsueh-Ying. Methods for Determination of Structure and Kinetics in the Study of Macromolecules Using Dissolution DNP NMR.

Degree: PhD, Chemistry, 2015, Texas A&M University

URL: http://hdl.handle.net/1969.1/155157

► Solution nuclear magnetic resonance spectroscopy (NMR) is known as a powerful tool in many fields because of its remarkable atomic resolution. However, its applications to… (more)

▼ Solution nuclear magnetic resonance spectroscopy (NMR) is known as a powerful tool in many fields because of its remarkable atomic resolution. However, its applications to non-equilibrium systems are limited due to low sensitivity of detection. A new technique, dissolution dynamic nuclear polarization (D-DNP) provides a unprecedented enhancement on NMR signals and opens a variety of applications of D-DNP NMR on time-resolved measurements at subsecond to second time scales. This thesis made a first attempt to monitor a protein kinetics using D-DNP NMR. A medium-size model protein (a two-state folder, L23) was directly hyperpolarized on 13C nuclei. The focus was placed on quantitative kinetic analysis and evaluations of possibilities that may affect the observed kinetics. In addition, this thesis included developments of experimental setups and NMR acquisition methods to address encountered problems in studies of large biomolecules using D-DNP. The refolding was triggered by changing the pH environment as a result of mixing aciddenatured L23 solution with a buffer of high pH. Chemical shift changes were observed in a series of time-resolved 13C spectra, indicating the formation of secondary structures. The re-folding rate constant was extracted by fitting fractions of folded/unfolded forms to a two-state folding kinetic model taking into account non-instantaneous mixing of two solutions. The assumption of equal relaxation time constants for folded/unfolded L23 and spectral artifacts arose from one-sided reaction were validated and evaluated. Consequently, the rate constants are in good agreement with those obtained from fluorescence experiments. In the above experiment, gas was used to inject the protein into an NMR tube. Due to turbulence from the rapid injection, protein samples are prone to foam which broadens NMR linewidths and leads to low signal-to-noise ratio. We have developed a new method to suppress air bubbles in which water was used to inject samples into a flow cell. Because of the incompressibility of liquid, the minimized residual sample motion was demonstrated as a parallel advantage that can alleviate signal loss in measurements using pulsed field gradients. In addition, the liquid driven injection permits studying biochemical reactions at a physiological condition since no need of using a mixture of organic solvent and water to dissolve protein sample for reducing propensity of foaming as in the above study. Conventional multidimensional NMR is not immediately compatible with the dissolution DNP to interrogate spin correlations due to the need of iterative measurements and the limitation of non-renewable hyperpolarization. We have developed a new method that integrates flow NMR into D-DNP to perform Hadamard spectroscopy and used entroy maximization algorithm to reconstruct pseudo-multidimensional spectra that contains spin correlations. As signal enhancement is critical for experiments that directly polarize large molecules, it is beneficial to monitor hyperpolarization level in the solid state… Advisors/Committee Members: Hilty, Christian (advisor), Cremer, Paul (committee member), Ross, Joseph (committee member), Son, Dong Hee (committee member).

Subjects/Keywords: dissolution DNP

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APA (6^th Edition):

Chen, H. (2015). Methods for Determination of Structure and Kinetics in the Study of Macromolecules Using Dissolution DNP NMR. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/155157

Chicago Manual of Style (16^th Edition):

Chen, Hsueh-Ying. “Methods for Determination of Structure and Kinetics in the Study of Macromolecules Using Dissolution DNP NMR.” 2015. Doctoral Dissertation, Texas A&M University. Accessed March 08, 2021. http://hdl.handle.net/1969.1/155157.

MLA Handbook (7^th Edition):

Chen, Hsueh-Ying. “Methods for Determination of Structure and Kinetics in the Study of Macromolecules Using Dissolution DNP NMR.” 2015. Web. 08 Mar 2021.

Vancouver:

Chen H. Methods for Determination of Structure and Kinetics in the Study of Macromolecules Using Dissolution DNP NMR. [Internet] [Doctoral dissertation]. Texas A&M University; 2015. [cited 2021 Mar 08]. Available from: http://hdl.handle.net/1969.1/155157.

Council of Science Editors:

Chen H. Methods for Determination of Structure and Kinetics in the Study of Macromolecules Using Dissolution DNP NMR. [Doctoral Dissertation]. Texas A&M University; 2015. Available from: http://hdl.handle.net/1969.1/155157

Texas A&M University

2. Lee, Youngbok. Application of Dissolution Dynamic Nuclear Polarization to the Characterization of Reactions Involving Large Molecules.

Degree: PhD, Chemistry, 2013, Texas A&M University

URL: http://hdl.handle.net/1969.1/149344

► Nuclear magnetic resonance (NMR) spectroscopy is one of the most important analytical tools for organic and biological chemistry. It provides not only detailed information on… (more)

▼ Nuclear magnetic resonance (NMR) spectroscopy is one of the most important analytical tools for organic and biological chemistry. It provides not only detailed information on the structure of small molecules and macromolecules, but also on molecular interactions. Because of the inherent low sensitivity of NMR, a long signal averaging time or a high spin concentration is often required. A variety of methods have been explored to improve the sensitivity of NMR. Especially, large signal gains can be obtained by hyperpolarization of the nuclear spins. NMR signals of hyperpolarized samples are enhanced by several orders of magnitude. Dissolution Dynamic Nuclear Polarization (D-DNP) is a versatile technique capable of polarizing many different nuclei in the solid state, and subsequently providing a hyperpolarized liquid sample following a dissolution step. The resulting signal enhancement has made it possible to obtain detailed information in research fields as varied as metabolic imaging or enzyme catalysis. This dissertation aims to extend the applicability of D-DNP into new areas of chemistry, which involve the characterization of interactions and reactions involving large molecules. In a first project, fluorine hyperpolarization is exploited to investigate protein-ligand interactions. The enhancement of 19F signal allows for the detection of submicromolar concentrations of fluorinated ligands in the strong-, intermediate-, and weak-binding regimes. Several NMR parameters are utilized to observe ligand binding to the macromolecule, and to determine dissociation constants. In a second project, competitive binding of ligands to the same binding pocket on a protein is investigated. Here, polarization flows from a first ligand hyperpolarized on protons to the protein, and then to the second ligand. The buildup in function of time of the signals due to this relayed nuclear Overhauser effect contains structural information on the binding epitope. In a third project, the aim is to directly detect a larger molecule, a polymer, which has been synthesized starting from hyperpolarized monomers. Using DNP, single scan observation of 13C, a common nucleus with large chemical shift dispersion, is possible. Time resolved 13C NMR spectroscopy in combination with kinetic models permits the description of polymerization reaction of the living anionic polymerization of styrene. In summary, several approaches have been investigated for utilizing a large hyperpolarization initially produced on small molecules, for the benefit of characterizing properties of macromolecules. These developments extend the capabilities of D-DNP and demonstrate the potential for leading to new applications in fields as diverse as drug discovery and polymer science. Advisors/Committee Members: Hilty, Christian (advisor), Barondeau, David P. (committee member), Liu , Wenshe (committee member), Young, Ryland (committee member).

Subjects/Keywords: NMR; DNP

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lee, Y. (2013). Application of Dissolution Dynamic Nuclear Polarization to the Characterization of Reactions Involving Large Molecules. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/149344

Chicago Manual of Style (16^th Edition):

Lee, Youngbok. “Application of Dissolution Dynamic Nuclear Polarization to the Characterization of Reactions Involving Large Molecules.” 2013. Doctoral Dissertation, Texas A&M University. Accessed March 08, 2021. http://hdl.handle.net/1969.1/149344.

MLA Handbook (7^th Edition):

Lee, Youngbok. “Application of Dissolution Dynamic Nuclear Polarization to the Characterization of Reactions Involving Large Molecules.” 2013. Web. 08 Mar 2021.

Vancouver:

Lee Y. Application of Dissolution Dynamic Nuclear Polarization to the Characterization of Reactions Involving Large Molecules. [Internet] [Doctoral dissertation]. Texas A&M University; 2013. [cited 2021 Mar 08]. Available from: http://hdl.handle.net/1969.1/149344.

Council of Science Editors:

Lee Y. Application of Dissolution Dynamic Nuclear Polarization to the Characterization of Reactions Involving Large Molecules. [Doctoral Dissertation]. Texas A&M University; 2013. Available from: http://hdl.handle.net/1969.1/149344

Texas A&M University

3. Ragavan, Mukundan. Dissolution Dynamic Nuclear Polarization of Polypeptides.

Degree: PhD, Biochemistry, 2014, Texas A&M University

URL: http://hdl.handle.net/1969.1/153352

► Nuclear Magnetic Resonance (NMR) spectroscopy provides remarkable site resolution, but often requires signal averaging because of low sensitivity. Dissolution dynamic nuclear polarization (DNP), which offers… (more)

▼ Nuclear Magnetic Resonance (NMR) spectroscopy provides remarkable site resolution, but often requires signal averaging because of low sensitivity. Dissolution dynamic nuclear polarization (DNP), which offers large signal enhancements, has been used to follow reactions involving small molecules that typically have long spin-lattice relaxation times. This thesis presents work in the development of dissolution DNP to directly hyper-polarize and observe polypeptides, which can subsequently be used for the study of a time dependent process, such as folding. Dissolution DNP involves hyperpolarizing samples in the solid state, dissolving the samples with a stream of hot solvent and rapid transfer of the sample into an NMR tube for measurement in the solution state. Since protein samples are prone to foam under conditions for rapid sample injection, solvent systems were optimized. Solvents such as water/acetonitrile and water/methanol mixtures were utilized. An unlabeled peptide, bacitracin, was hyperpolarized on ^(1)H nuclei and enhancements of 30, 45 and 180 were obtained for amide, aliphatic and aromatic protons respectively. Although these enhancements are already significant, loss of hyperpolarization during sample injection was further alleviated by the use of isotopically enriched polypeptides. In [^(13)C, 50% ^(2)H] labeled samples of denatured L23, a 96 amino acid long ribosomal protein, signal enhancements of more than 500 times were obtained on the ^(13)C nuclei. This signal enhancement was then exploited to follow the protein folding process, using L23 as a model. Time resolved spectra of hyperpolarized L23 were measured after a pH jump and protein folding was monitored by observing changes in the carbonyl region of the spectra, which are indicative of the formation of secondary structures. Despite signal overlap in the protein spectra, using the statistical distribution of ^(13)C chemical shifts, the fractions of secondary structure elements were estimated for each scan of the DNP-NMR experiment. Additionally, individual resonances for methyl groups upfield of other protein resonances became resolved in the later transients. An option for the improvement of such site resolution by NMR experiments using coherence selection is discussed. While DNP-NMR offers the capability to observe transient species, identification of such species is difficult in cases where not all chemical shifts are known. Here, a new strategy for the analysis of DNP-NMR data is proposed based on non-negative matrix factorization (NNMF). NNMF enables identification of various sources that contribute to an observed signal. This capability is demonstrated using a series of spectra measured from an enzymatic conversion reaction of oxaloacetic acid to malic acid. Simulations were carried out to evaluate the performance of NNMF under different experimental constraints, and the strengths and limitations of the method are discussed based on the simulations. Advisors/Committee Members: Raushel, Frank (advisor), Hilty, Christian (advisor), Sacchettini, James (committee member), Straight, Paul (committee member).

Subjects/Keywords: dnp; protein; nmr

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ragavan, M. (2014). Dissolution Dynamic Nuclear Polarization of Polypeptides. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/153352

Chicago Manual of Style (16^th Edition):

Ragavan, Mukundan. “Dissolution Dynamic Nuclear Polarization of Polypeptides.” 2014. Doctoral Dissertation, Texas A&M University. Accessed March 08, 2021. http://hdl.handle.net/1969.1/153352.

MLA Handbook (7^th Edition):

Ragavan, Mukundan. “Dissolution Dynamic Nuclear Polarization of Polypeptides.” 2014. Web. 08 Mar 2021.

Vancouver:

Ragavan M. Dissolution Dynamic Nuclear Polarization of Polypeptides. [Internet] [Doctoral dissertation]. Texas A&M University; 2014. [cited 2021 Mar 08]. Available from: http://hdl.handle.net/1969.1/153352.

Council of Science Editors:

Ragavan M. Dissolution Dynamic Nuclear Polarization of Polypeptides. [Doctoral Dissertation]. Texas A&M University; 2014. Available from: http://hdl.handle.net/1969.1/153352

4. Guido, Sara D, Dr. Creating an Interactive DNP Project Repository:A Model for Change.

Degree: DNP, Nursing, 2012, University of San Francisco

URL: https://repository.usfca.edu/dnp/30

► The creation of systems that can provide bridges to information technology requires rethinking old ways of doing business. In the past, individual universities and… (more)

Subjects/Keywords: DNP Repository; Final DNP Projects; Evidence Based Practice; DNP Projects; Nursing; Nursing Administration; Other Nursing

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Guido, Sara D, D. (2012). Creating an Interactive DNP Project Repository:A Model for Change. (Thesis). University of San Francisco. Retrieved from https://repository.usfca.edu/dnp/30

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Guido, Sara D, Dr. “Creating an Interactive DNP Project Repository:A Model for Change.” 2012. Thesis, University of San Francisco. Accessed March 08, 2021. https://repository.usfca.edu/dnp/30.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Guido, Sara D, Dr. “Creating an Interactive DNP Project Repository:A Model for Change.” 2012. Web. 08 Mar 2021.

Vancouver:

Guido, Sara D D. Creating an Interactive DNP Project Repository:A Model for Change. [Internet] [Thesis]. University of San Francisco; 2012. [cited 2021 Mar 08]. Available from: https://repository.usfca.edu/dnp/30.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Guido, Sara D D. Creating an Interactive DNP Project Repository:A Model for Change. [Thesis]. University of San Francisco; 2012. Available from: https://repository.usfca.edu/dnp/30

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

5. Smith, Alicia. Instrument and Method development for High Field Dynamic Nuclear Polarization with Magic Angle Spinning Spectroscopy at 25 K.

Degree: 2017, University of California – eScholarship, University of California

URL: http://www.escholarship.org/uc/item/0kj7p95q

► The aim of the work presented here has been to optimize the sensitivity of nuclear magnetic resonance (NMR) through the use of the technique of… (more)

▼ The aim of the work presented here has been to optimize the sensitivity of nuclear magnetic resonance (NMR) through the use of the technique of dynamic nuclear polarization (DNP) and magic angle spinning (MAS). DNP is a technique where the polarization from free electron “DNP agent” can be transferred to hyperfine coupled nuclei through microwave irradiation of the sample. The greatest nuclear polarizations are to be expected when the starting thermal electron and nuclear polarization is maximized by operating MAS at a helium cryogenic temperatures. Through a collaboration with Revolution NMR LLC and Bruker Biospin we have development a Cryo DNP-MAS probe operation at a temperature of 25 K and spin rates of 8 kHz. We have measured the microwave beam transmission through each component of the Cryo DNP-MAS probe and optimized the NMR coil and rotor material to maximize the microwave transmission to the sample. We have found that changing the geometry of the radio frequency NMR coil allowing for greater transmission of microwaves doubled the resulting nuclear signal enhancement. Much of the current development in DNP has focused on tethered nitroxide radicals as the DNP agents, but the design of potent radicals for DNP, in particular under magic angle spinning (MAS) conditions, is still debated and relies on empirical trial and error as the contributing factors for MAS DNP enhancement are not entirely understood. Significant instrumental effort is needed to measure the electron paramagnetic resonance EPR parameters at magnetic fields of 7 T or greater. This work presents the development of an EPR spectrometer at 7 T in order to measure the electron spin dynamics contribution factors to DNP. We have found that the nuclear depolarization induced by MAS is determined by the spin-lattice relaxation time of the nitroxide DNP agent, and once this depolarization is accounted for different tethered nitroxide radical designs have the same DNP signal enhancement. Finally the signal enhancement capabilities of the Han labs home built DNP system is demonstrated through direct enhancement of aluminum spins on the surface of a mesoporous material targeting catalytically active aluminum spins on the surface. When the nitroxide radical is tailored to have a favorable electrostatic interaction with the surface species, the aluminum NMR signal enhancement can be up to 10 fold.

Subjects/Keywords: Physical chemistry; DNP; NMR; Polarization

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APA (6^th Edition):

Smith, A. (2017). Instrument and Method development for High Field Dynamic Nuclear Polarization with Magic Angle Spinning Spectroscopy at 25 K. (Thesis). University of California – eScholarship, University of California. Retrieved from http://www.escholarship.org/uc/item/0kj7p95q

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Smith, Alicia. “Instrument and Method development for High Field Dynamic Nuclear Polarization with Magic Angle Spinning Spectroscopy at 25 K.” 2017. Thesis, University of California – eScholarship, University of California. Accessed March 08, 2021. http://www.escholarship.org/uc/item/0kj7p95q.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Smith, Alicia. “Instrument and Method development for High Field Dynamic Nuclear Polarization with Magic Angle Spinning Spectroscopy at 25 K.” 2017. Web. 08 Mar 2021.

Vancouver:

Smith A. Instrument and Method development for High Field Dynamic Nuclear Polarization with Magic Angle Spinning Spectroscopy at 25 K. [Internet] [Thesis]. University of California – eScholarship, University of California; 2017. [cited 2021 Mar 08]. Available from: http://www.escholarship.org/uc/item/0kj7p95q.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Smith A. Instrument and Method development for High Field Dynamic Nuclear Polarization with Magic Angle Spinning Spectroscopy at 25 K. [Thesis]. University of California – eScholarship, University of California; 2017. Available from: http://www.escholarship.org/uc/item/0kj7p95q

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Sydney

6. Rej, Ewa. Hyperpolarized Nanodiamond for Magnetic Resonance Imaging .

Degree: 2016, University of Sydney

URL: http://hdl.handle.net/2123/15915

► This thesis describes a new MRI contrast agent based on hyperpolarized 13C in nanodiamond. Nanodiamonds are readily available, non-toxic, can be surface functionalized, and have… (more)

Subjects/Keywords: DNP; nanodiamond; NMR; hyperpolarization; MRI

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Rej, E. (2016). Hyperpolarized Nanodiamond for Magnetic Resonance Imaging . (Thesis). University of Sydney. Retrieved from http://hdl.handle.net/2123/15915

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Rej, Ewa. “Hyperpolarized Nanodiamond for Magnetic Resonance Imaging .” 2016. Thesis, University of Sydney. Accessed March 08, 2021. http://hdl.handle.net/2123/15915.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Rej, Ewa. “Hyperpolarized Nanodiamond for Magnetic Resonance Imaging .” 2016. Web. 08 Mar 2021.

Vancouver:

Rej E. Hyperpolarized Nanodiamond for Magnetic Resonance Imaging . [Internet] [Thesis]. University of Sydney; 2016. [cited 2021 Mar 08]. Available from: http://hdl.handle.net/2123/15915.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Rej E. Hyperpolarized Nanodiamond for Magnetic Resonance Imaging . [Thesis]. University of Sydney; 2016. Available from: http://hdl.handle.net/2123/15915

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

7. Milner, Melissa C. Analysis of the Impact of Hours of Simulation on HESI Scores.

Degree: 2017, Regis University

URL: http://epublications.regis.edu/theses/824

► Executive Summary Project Title: Analysis of the impact of hours of simulation on HESI scores. Statement of problem: Undergraduate nursing programs are challenged to… (more)

▼ Executive Summary Project Title: Analysis of the impact of hours of simulation on HESI scores. Statement of problem: Undergraduate nursing programs are challenged to develop high cognitive skills in students and prepare them for practice readiness. Limited clinical placements that offer a narrow exposure to clinical experiences to prepare nursing students adequately to apply their knowledge are a growing concern. Simulation experiences allow students the opportunity to acquire competencies necessary to apply knowledge to practice. Is there a direct relationship between increased hours of simulation to students’ readiness for practice? Purpose: To determine if there is a relationship between hours of simulation received and student performance on HESI exam to better explain the relationship of simulation to student knowledge acquisition and application. Goals: Provide evidence of impact of simulation on nursing student knowledge. This study will provide information that may guide undergraduate nursing curriculum development specifically surrounding clinical hours. Objectives: To determine if there is a relationship between the number of hours of simulation received and student performance on a standardized exam. Plan: Challenges for clinical placements required innovative strategies to meet the clinical requirements within this organization. The use of simulation in place of clinical hours was being done, but cohorts were receiving different numbers of hours. A retrospective look at each of the cohorts was done to determine simulation hours received. Data was collected from each cohort’s HESI exam results and compared. Outcomes and Results: The analysis of data revealed that 6 hours of simulation is a minimum number of hours that will have a positive impact on student learning, and 12 hours showed the greatest impact on students within this study. The data does not appear to reach saturation one cannot prove that only 6 or 12 hours of simulation should be considered as all levels are statistically significant. One cannot prove that additional hours is a waste of time or that student learning has reached a plateau. Advisors/Committee Members: Catherine Witt.

Subjects/Keywords: DNP Project; Undergraduate Nursing; Nursing Clinical hours

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APA (6^th Edition):

Milner, M. C. (2017). Analysis of the Impact of Hours of Simulation on HESI Scores. (Thesis). Regis University. Retrieved from http://epublications.regis.edu/theses/824

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Milner, Melissa C. “Analysis of the Impact of Hours of Simulation on HESI Scores.” 2017. Thesis, Regis University. Accessed March 08, 2021. http://epublications.regis.edu/theses/824.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Milner, Melissa C. “Analysis of the Impact of Hours of Simulation on HESI Scores.” 2017. Web. 08 Mar 2021.

Vancouver:

Milner MC. Analysis of the Impact of Hours of Simulation on HESI Scores. [Internet] [Thesis]. Regis University; 2017. [cited 2021 Mar 08]. Available from: http://epublications.regis.edu/theses/824.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Milner MC. Analysis of the Impact of Hours of Simulation on HESI Scores. [Thesis]. Regis University; 2017. Available from: http://epublications.regis.edu/theses/824

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

8. Gladson, Emma. Experiences of Providers in Caring for the Obese Hispanic Population.

Degree: 2019, Regis University

URL: https://epublications.regis.edu/theses/946

► The national obesity rate continues to rise along with numerous correlating health disparities in Colorado. According to Andolf and Fisichella (2018), obesity currently affects… (more)

Subjects/Keywords: DNP project; obesity; Hispanics; healthcare providers

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Gladson, E. (2019). Experiences of Providers in Caring for the Obese Hispanic Population. (Thesis). Regis University. Retrieved from https://epublications.regis.edu/theses/946

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Gladson, Emma. “Experiences of Providers in Caring for the Obese Hispanic Population.” 2019. Thesis, Regis University. Accessed March 08, 2021. https://epublications.regis.edu/theses/946.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Gladson, Emma. “Experiences of Providers in Caring for the Obese Hispanic Population.” 2019. Web. 08 Mar 2021.

Vancouver:

Gladson E. Experiences of Providers in Caring for the Obese Hispanic Population. [Internet] [Thesis]. Regis University; 2019. [cited 2021 Mar 08]. Available from: https://epublications.regis.edu/theses/946.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Gladson E. Experiences of Providers in Caring for the Obese Hispanic Population. [Thesis]. Regis University; 2019. Available from: https://epublications.regis.edu/theses/946

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Sydney

9. Waddington, David Eric Jenner. Diamonds On The Inside: Imaging Nanodiamonds With Hyperpolarized MRI .

Degree: 2017, University of Sydney

URL: http://hdl.handle.net/2123/17948

► Nontoxic nanodiamonds (NDs) have proven useful as a vector for therapeutic drug delivery to cancers and as optical bioprobes of subcellular processes. Despite their potential… (more)

Subjects/Keywords: nanodiamond; MRI; theranostics; DNP; hyperpolarization; NMR

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Waddington, D. E. J. (2017). Diamonds On The Inside: Imaging Nanodiamonds With Hyperpolarized MRI . (Thesis). University of Sydney. Retrieved from http://hdl.handle.net/2123/17948

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Waddington, David Eric Jenner. “Diamonds On The Inside: Imaging Nanodiamonds With Hyperpolarized MRI .” 2017. Thesis, University of Sydney. Accessed March 08, 2021. http://hdl.handle.net/2123/17948.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Waddington, David Eric Jenner. “Diamonds On The Inside: Imaging Nanodiamonds With Hyperpolarized MRI .” 2017. Web. 08 Mar 2021.

Vancouver:

Waddington DEJ. Diamonds On The Inside: Imaging Nanodiamonds With Hyperpolarized MRI . [Internet] [Thesis]. University of Sydney; 2017. [cited 2021 Mar 08]. Available from: http://hdl.handle.net/2123/17948.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Waddington DEJ. Diamonds On The Inside: Imaging Nanodiamonds With Hyperpolarized MRI . [Thesis]. University of Sydney; 2017. Available from: http://hdl.handle.net/2123/17948

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Iowa State University

10. Hanrahan, Michael Patrick. Characterization of inorganic semiconductors by sensitivity-enhanced multidimensional solid-state NMR spectroscopy.

Degree: 2020, Iowa State University

URL: https://lib.dr.iastate.edu/etd/18322

► This dissertation describes the development of sensitivity-enhanced solid-state nuclear magnetic resonance (NMR) spectroscopy techniques for the characterization of inorganic semiconductors. Inorganic semiconductors will play a… (more)

▼ This dissertation describes the development of sensitivity-enhanced solid-state nuclear magnetic resonance (NMR) spectroscopy techniques for the characterization of inorganic semiconductors. Inorganic semiconductors will play a vital role in the development of next generation energy materials and understanding the structure of these materials will enable the development of better performing devices. Inorganic semiconductors synthesized as nanomaterials are of interest because of increased tuneability of the band gap through modifications in the size, surface ligands or composition of the particles. Ultimately, the surface structure of nanomaterials will greatly affect their optoelectronic properties, making it vital to obtain a molecular-level understanding of the surface structure. Solid-state NMR spectroscopy is an ideal characterization method for determining the surface structure of nanomaterials because it probes the local chemical environments of the surface. However, surface solid-state NMR experiments are often challenging to obtain because of the low concentration of surface sites and the use sensitivity enhanced NMR methods such as proton detection or dynamic nuclear polarization (DNP) is needed. Chapter 2 focuses on the development of fast magic angle spinning (MAS) and indirect detection methods to characterize the surface structure of silicon nanocrystals (NCs). Using 2D dipolar and scalar 1H{29Si} heteronuclear correlations (HETCOR) solid-state NMR spectra were used to reveal the surface structure of Si NCs and identify the different surface silicon environments. Using the 1H{29Si} refocused insensitive nuclei enhanced by polarization transfer (INEPT) experiments it is possible to differentiate the NMR signals associated with different surface hydride species. Varying the 29Si evolution time in the INEPT experiment and fitting the oscillation of the NMR signal allows for the determination of the relative populations of the different surface hydride species. From the refocused INEPT experiments, it was determined that the monohydride species is the predominate surface hydride in the hydride terminated Si NCs. When the hydride terminated Si NCs were functionalized with dodecyl groups a reduction in the relative populations of di- and trihydrides was observed, which is consistent with the hypothesis that the trihydride group is primarily responsible for initiating the surface functionalization process. The work in Chapter 3 builds off of the work presented in chapter 2 in order to probe the location of phosphorus doped into Si NCs (P:Si NCs). When the phosphorus is doped into the Si NCs, surface phosphine groups (*PH and *PH2) are formed. These groups make up 20% of the surface functional groups in the hydride terminated P:Si NCs (P:Si-H NCs). Through analysis of the dipolar and scalar 1H{31P} HETCOR interactions it was determined that the majority of the phosphorus that was doped into the Si NCs is located at the surface of the P:Si NCs. 29Si{31P} scalar correlations were used to confirm that all of the…

Subjects/Keywords: DNP SENS; Nanoparticles; Solid-State NMR

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APA (6^th Edition):

Hanrahan, M. P. (2020). Characterization of inorganic semiconductors by sensitivity-enhanced multidimensional solid-state NMR spectroscopy. (Thesis). Iowa State University. Retrieved from https://lib.dr.iastate.edu/etd/18322

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Hanrahan, Michael Patrick. “Characterization of inorganic semiconductors by sensitivity-enhanced multidimensional solid-state NMR spectroscopy.” 2020. Thesis, Iowa State University. Accessed March 08, 2021. https://lib.dr.iastate.edu/etd/18322.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Hanrahan, Michael Patrick. “Characterization of inorganic semiconductors by sensitivity-enhanced multidimensional solid-state NMR spectroscopy.” 2020. Web. 08 Mar 2021.

Vancouver:

Hanrahan MP. Characterization of inorganic semiconductors by sensitivity-enhanced multidimensional solid-state NMR spectroscopy. [Internet] [Thesis]. Iowa State University; 2020. [cited 2021 Mar 08]. Available from: https://lib.dr.iastate.edu/etd/18322.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Hanrahan MP. Characterization of inorganic semiconductors by sensitivity-enhanced multidimensional solid-state NMR spectroscopy. [Thesis]. Iowa State University; 2020. Available from: https://lib.dr.iastate.edu/etd/18322

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Texas A&M University

11. Kim, Yaewon. Methods for Ligand Screening by Dissolution DNP Assisted NMR Spectroscopy.

Degree: PhD, Chemistry, 2018, Texas A&M University

URL: http://hdl.handle.net/1969.1/174592

► NMR spectroscopy is one of the front-line techniques in drug screening for binding identification and affinity determination. A critical issue that limits the scope of… (more)

▼ NMR spectroscopy is one of the front-line techniques in drug screening for binding identification and affinity determination. A critical issue that limits the scope of NMR in screening applications is low detection sensitivity. A solution can be provided by the hyperpolarization technique of dissolution dynamic nuclear polarization (D-DNP). With a several thousand-fold enhancement of NMR signals, the need for signal averaging and the problems arising due to low protein or ligand solubility can be avoided. v19F-NMR relaxometry for ligand screening using D-DNP is demonstrated. With a well polarizable reporter ligand containing v19F atoms, binding affinities of non-fluorinated ligands can be determined under competitive binding through transverse relaxation (Tv2) measurements. The enhanced sensitivity by the D-DNP method allows lowering the protein and ligand concentrations to the micromolar to sub-micromolar range. Despite the substantial signal enhancement by DNP, the achievable throughput is limited because the most commonly available instrumentation for D-DNP provides a single hyperpolarized sample after each polarization process. We demonstrate that multiplexed NMR detection can improve the throughput of D-DNP experiments by permitting parallelized screening experiments with a single hyperpolarized aliquot of ligand. In combination with a flow injection system capable of mixing the hyperpolarized sample with several different secondary samples, Tv2 relaxation times of the reporter ligand can be obtained from multiple channels simultaneously at desired concentration ratios of the reporter to competitive ligand concentrations. This method extends the range of binding affinity detectable in a single experiment to three orders of magnitude. It greatly reduces the chance of missing the binding detection due to non-optimal sample concentrations in every individual experiment. This multiplexed D-DNP approach may be more broadly applied to chemical or biochemical problems requiring variable-dependent measurements. Advisors/Committee Members: Hilty, Christian (advisor), Russell, David (committee member), Wooley, Karen (committee member), McDougall, Mary (committee member).

Subjects/Keywords: Hyperpolarization; Dissolution DNP; Protein-ligand interactions

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APA (6^th Edition):

Kim, Y. (2018). Methods for Ligand Screening by Dissolution DNP Assisted NMR Spectroscopy. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/174592

Chicago Manual of Style (16^th Edition):

Kim, Yaewon. “Methods for Ligand Screening by Dissolution DNP Assisted NMR Spectroscopy.” 2018. Doctoral Dissertation, Texas A&M University. Accessed March 08, 2021. http://hdl.handle.net/1969.1/174592.

MLA Handbook (7^th Edition):

Kim, Yaewon. “Methods for Ligand Screening by Dissolution DNP Assisted NMR Spectroscopy.” 2018. Web. 08 Mar 2021.

Vancouver:

Kim Y. Methods for Ligand Screening by Dissolution DNP Assisted NMR Spectroscopy. [Internet] [Doctoral dissertation]. Texas A&M University; 2018. [cited 2021 Mar 08]. Available from: http://hdl.handle.net/1969.1/174592.

Council of Science Editors:

Kim Y. Methods for Ligand Screening by Dissolution DNP Assisted NMR Spectroscopy. [Doctoral Dissertation]. Texas A&M University; 2018. Available from: http://hdl.handle.net/1969.1/174592

University of Sydney

12. Boele, Thomas. Altered Carbon: Developing Nanodiamonds for Hyperpolarized MRI .

Degree: 2021, University of Sydney

URL: http://hdl.handle.net/2123/24582

► Nanodiamond is a promising biocompatible substrate for targeted drug delivery and fluorescent imaging. Optical techniques, although useful on the cellular level, are limited by penetration… (more)

Subjects/Keywords: nanodiamond; hyperpolarization; MRI; NMR; DNP; theranostics

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APA (6^th Edition):

Boele, T. (2021). Altered Carbon: Developing Nanodiamonds for Hyperpolarized MRI . (Thesis). University of Sydney. Retrieved from http://hdl.handle.net/2123/24582

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Boele, Thomas. “Altered Carbon: Developing Nanodiamonds for Hyperpolarized MRI .” 2021. Thesis, University of Sydney. Accessed March 08, 2021. http://hdl.handle.net/2123/24582.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Boele, Thomas. “Altered Carbon: Developing Nanodiamonds for Hyperpolarized MRI .” 2021. Web. 08 Mar 2021.

Vancouver:

Boele T. Altered Carbon: Developing Nanodiamonds for Hyperpolarized MRI . [Internet] [Thesis]. University of Sydney; 2021. [cited 2021 Mar 08]. Available from: http://hdl.handle.net/2123/24582.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Boele T. Altered Carbon: Developing Nanodiamonds for Hyperpolarized MRI . [Thesis]. University of Sydney; 2021. Available from: http://hdl.handle.net/2123/24582

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Texas A&M University

13. Zeng, Haifeng. Quantitative Determination of Chemical Processes by Dynamic Nuclear Polarization Enhanced Nuclear Magnetic Resonance Spectroscopy.

Degree: PhD, Chemistry, 2012, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-2012-05-11103

► Dissolution dynamic nuclear polarization (DNP) provides several orders of magnitude of NMR signal enhancement by converting the much larger electron spin polarization to nuclear spin… (more)

▼ Dissolution dynamic nuclear polarization (DNP) provides several orders of magnitude of NMR signal enhancement by converting the much larger electron spin polarization to nuclear spin polarization. Polarization occurs at low temperature (1.4K) and is followed by quickly dissolving the sample for room temperature NMR detection. DNP is generally applicable to almost any small molecules and can polarize various nuclei including 1H, 19F and 13C. The large signal from DNP enhancement reduces the limit of detection to micromolar or sub-micromolar concentration in a single scan. Since DNP enhancement often provides the only source for the observable signal, it enables tracking of the polarization flow. Therefore, DNP is ideal for studying chemical processes. Here, quantitative tools are developed to separate kinetics and spin relaxation, as well as to obtain structural information from these measurements. Techniques needed for analyzing DNP polarized sample are different from those used in conventional NMR because a large, yet non-renewable hyperpolarization is available. Using small flip angle pulse excitation, the hyperpolarization can still be divided into multiple scans. Based on this principle, a scheme is presented that allows reconstruction of indirect spectral dimensions similarly to conventional 2D NMR. Additionally, small flip angle pulses can be used to obtain a succession of scans separated in time. A model describing the combined effects of the evolution of a chemical process and of spin-lattice relaxation is shown. Applied to a Diels-Alder reaction, it permitted measuring kinetics along with the effects of auto- and cross-relaxation. DNP polarization of small molecules also shows significant promise for studying protein-ligand interaction. The binding of fluorinated ligands to the protease trypsin was studied through the observation of various NMR parameter changes, such as line width, signal intensity and chemical shift of the ligands. Intermolecular polarization transfer from hyperpolarized ligand to protein can further provide information about the binding pocket of the protein. As an alternative to direct observation of protein signal, a model is presented to describe a two-step intermolecular polarization transfer between competitively binding ligands mediated through the common binding pocket of the protein. The solutions of this model relate the evolution of signal intensities to the intermolecular cross relaxation rates, which depend on individual distances in the binding epitope. In summary, DNP provides incomparable sensitivity, speed and selectivity to NMR. Quantitative models such as those discussed here enable taking full advantage of these benefits for the study of chemical processes. Advisors/Committee Members: Hilty, Christian (advisor), Lindahl, Paul A. (committee member), Lucchese, Robert R. (committee member), Ji, Jim(Xiuquan) (committee member).

Subjects/Keywords: DNP; NMR; Kinetics; Spin Relaxation; Protein Ligand Interaction

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Zeng, H. (2012). Quantitative Determination of Chemical Processes by Dynamic Nuclear Polarization Enhanced Nuclear Magnetic Resonance Spectroscopy. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2012-05-11103

Chicago Manual of Style (16^th Edition):

Zeng, Haifeng. “Quantitative Determination of Chemical Processes by Dynamic Nuclear Polarization Enhanced Nuclear Magnetic Resonance Spectroscopy.” 2012. Doctoral Dissertation, Texas A&M University. Accessed March 08, 2021. http://hdl.handle.net/1969.1/ETD-TAMU-2012-05-11103.

MLA Handbook (7^th Edition):

Zeng, Haifeng. “Quantitative Determination of Chemical Processes by Dynamic Nuclear Polarization Enhanced Nuclear Magnetic Resonance Spectroscopy.” 2012. Web. 08 Mar 2021.

Vancouver:

Zeng H. Quantitative Determination of Chemical Processes by Dynamic Nuclear Polarization Enhanced Nuclear Magnetic Resonance Spectroscopy. [Internet] [Doctoral dissertation]. Texas A&M University; 2012. [cited 2021 Mar 08]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2012-05-11103.

Council of Science Editors:

Zeng H. Quantitative Determination of Chemical Processes by Dynamic Nuclear Polarization Enhanced Nuclear Magnetic Resonance Spectroscopy. [Doctoral Dissertation]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2012-05-11103

14. Matos, Luís Miguel Rodrigues de. Aplicação da ferramenta metodológica TRIZ no desenvolvimento de novos produtos industriais em empresas nacionais.

Degree: 2017, Repositório Científico do Instituto Politécnico de Lisboa

URL: https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ipl.pt:10400.21/7968

►

Trabalho final de mestrado para obtenção do grau de Mestre em Engenharia Mecânica

As exigências crescentes e as rápidas mudanças nos mercados obrigam as organizações… (more)

▼

Trabalho final de mestrado para obtenção do grau de Mestre em Engenharia Mecânica

As exigências crescentes e as rápidas mudanças nos mercados obrigam as organizações a pensarem cada vez mais na inovação e melhoria contínua. Hoje em dia qualquer estratégia de crescimento, e até mesmo a própria sobrevivência nos mercados, passa cada vez mais pela aplicação de novas abordagens e metodologias de gestão. A metodologia TRIZ (Teoria da Resolução Inventiva de Problemas) tem vindo a ganhar popularidade tanto a nível académico, como a nível empresarial. Esta metodologia promove a inovação sistemática e a procura de novas soluções para os problemas existentes, apresentando técnicas e ferramentas para a resolução de problemas relativos à concepção de produtos, e também já de serviços e de processos, permitindo assim desenvolver soluções inovadoras. A TRIZ permite também que a inovação deixe de ser esporádica, não dependendo apenas da capacidade individual de cada stakeholder e de momentos de inspiração, evoluindo para a inovação sistemática que pode ser implementada, gerida e ensinada. O estudo desenvolvido no âmbito da presente dissertação centrou-se na abordagem e interpretação da utilização da metodologia TRIZ, em busca de novas formas de solucionar problemas, identificando as suas ferramentas de apoio. Outro conceito explorado e relacionado com a TRIZ é o conceito DNP, sendo integrado de múltiplas abordagens que foram exploradas. O presente estudo visa analisar os dois conceitos e a forma como se relacionam seguindo de doutrinas inovativas apelando à criatividade. No âmbito desta dissertação e através da análise dos diferentes campos investigados, foi proposto um modelo diagramático contemplando conceitos e relações entre os mesmos. De forma a analisar a viabilidade da implementação desse mesmo modelo diagramático em meio industrial, apresentou-se um caso de estudo realizado numa empresa que utiliza a TRIZ, e que através de uma análise conclusiva, se verifica que o modelo proposto pode ser utilizado como suporte na resolução de problemas de carácter inovativo e criativo inerentes à implementação de novos processos de gestão e na sua melhoria.

Growing demands and rapid changes in markets compel organizations to think more about innovation and continuous improvement. Nowadays, any growth strategy, and even its own survival in the markets, is increasingly being applied by new approaches and management methodologies. The TRIZ methodology (Theory of Inventive Problem Solving) has been gaining popularity both academically and business level. This methodology promotes systematic innovation and the search for new solutions to existing problems, presenting techniques and tools for solving problems related to product design, as well as services and processes, thus allowing the development of innovative solutions. The TRIZ also allows innovation to cease to be sporadic, not only depending on the individual capacity of each stakeholder and moments of inspiration, evolving into systematic innovation that can be implemented, managed…

Advisors/Committee Members: Dias, Ana Sofia Martins da Eira.

Subjects/Keywords: Estratégia; Inovação; Resolução de problemas; TRIZ; DNP; Strategy; Innovation; Problem solving

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Matos, L. M. R. d. (2017). Aplicação da ferramenta metodológica TRIZ no desenvolvimento de novos produtos industriais em empresas nacionais. (Thesis). Repositório Científico do Instituto Politécnico de Lisboa. Retrieved from https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ipl.pt:10400.21/7968

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Matos, Luís Miguel Rodrigues de. “Aplicação da ferramenta metodológica TRIZ no desenvolvimento de novos produtos industriais em empresas nacionais.” 2017. Thesis, Repositório Científico do Instituto Politécnico de Lisboa. Accessed March 08, 2021. https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ipl.pt:10400.21/7968.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Matos, Luís Miguel Rodrigues de. “Aplicação da ferramenta metodológica TRIZ no desenvolvimento de novos produtos industriais em empresas nacionais.” 2017. Web. 08 Mar 2021.

Vancouver:

Matos LMRd. Aplicação da ferramenta metodológica TRIZ no desenvolvimento de novos produtos industriais em empresas nacionais. [Internet] [Thesis]. Repositório Científico do Instituto Politécnico de Lisboa; 2017. [cited 2021 Mar 08]. Available from: https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ipl.pt:10400.21/7968.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Matos LMRd. Aplicação da ferramenta metodológica TRIZ no desenvolvimento de novos produtos industriais em empresas nacionais. [Thesis]. Repositório Científico do Instituto Politécnico de Lisboa; 2017. Available from: https://www.rcaap.pt/detail.jsp?id=oai:repositorio.ipl.pt:10400.21/7968

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

15. Kerley, Lori. Student Nurse Advocacy: Supporting the Future to Save Our Profession.

Degree: 2016, Regis University

URL: http://epublications.regis.edu/theses/805

► This student nurse advocacy capstone project was an evidence-based online educational intervention that focused on increasing the knowledge of the nursing staff that work… (more)

▼ This student nurse advocacy capstone project was an evidence-based online educational intervention that focused on increasing the knowledge of the nursing staff that work with student nurses. Problem Exit interviews of employees that were student nurses conducted revealed that the unprofessional behavior of the clinical bedside staff lead to a 60 percent exit rate. The capstone project addressed this issue as well as answered this question: Will a formal advocacy educational offering to professional bedside clinicians result in a change in the recruitment and retention rates of student nurses that are currently employed at an urban hospital (UH) and enrolled in the School of Nursing Registered Nurse (SONRN) program? The current practice did not include an educational offering and the outcome was anticipated to increase the knowledge, self-efficacy, and perceived potential for advocacy of the bedside clinician working with student nurses. Goal Forge positive professional relationships between practicing bedside clinicians and student nurses. Change the recruitment and retention rates of SONRN student nurses that are employed at UH. Examine the correlation of perceived potential for advocacy as it relates to changes in RN self-efficacy with recruitment and retention rates of student nurses Objectives To guide the standards for bedside clinicians’ professional conduct towards student nurses. Plan The need for this scholarly project was identified during a process improvement meeting concerning recruitment and retention of student nurses that work at UH. The organizational leadership was presented with a plan for the capstone proposal and supported the introduction of an educational intervention that was founded on evidence-based information from the nursing literature. The effectiveness of this intervention was based upon pre and post education survey data. Outcomes and Results The data analysis revealed statistical significance in t-test static between the mean pre-mastery and post-mastery quizzes scores. Statistical difference between pre and post GSE and SPPAT surveys. Correlations between tenure and the GSE as well as tenure and SPPAT scores noted practice implications warranting further investigation. The organization adopted the intervention as a training program for the student advocates. Advisors/Committee Members: Cullen, Patricia L., Claywell, Lora.

Subjects/Keywords: DNP capstone; student nurse advocacy; student advocacy; recruitment; retention

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Kerley, L. (2016). Student Nurse Advocacy: Supporting the Future to Save Our Profession. (Thesis). Regis University. Retrieved from http://epublications.regis.edu/theses/805

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kerley, Lori. “Student Nurse Advocacy: Supporting the Future to Save Our Profession.” 2016. Thesis, Regis University. Accessed March 08, 2021. http://epublications.regis.edu/theses/805.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kerley, Lori. “Student Nurse Advocacy: Supporting the Future to Save Our Profession.” 2016. Web. 08 Mar 2021.

Vancouver:

Kerley L. Student Nurse Advocacy: Supporting the Future to Save Our Profession. [Internet] [Thesis]. Regis University; 2016. [cited 2021 Mar 08]. Available from: http://epublications.regis.edu/theses/805.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kerley L. Student Nurse Advocacy: Supporting the Future to Save Our Profession. [Thesis]. Regis University; 2016. Available from: http://epublications.regis.edu/theses/805

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

16. Kautz, Mandy. Implementing a Residency Program to Affect Float Pool Nurse Retention Rates.

Degree: 2017, Regis University

URL: http://epublications.regis.edu/theses/825

► As new generations of fresh faced nursing graduates enter the workforce, they are faced with many difficult challenges. Any number of issues can influence… (more)

Subjects/Keywords: DNP Project; Nursing Residency; Turnover Rates; Revised Nursing Work Index

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APA (6^th Edition):

Kautz, M. (2017). Implementing a Residency Program to Affect Float Pool Nurse Retention Rates. (Thesis). Regis University. Retrieved from http://epublications.regis.edu/theses/825

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kautz, Mandy. “Implementing a Residency Program to Affect Float Pool Nurse Retention Rates.” 2017. Thesis, Regis University. Accessed March 08, 2021. http://epublications.regis.edu/theses/825.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kautz, Mandy. “Implementing a Residency Program to Affect Float Pool Nurse Retention Rates.” 2017. Web. 08 Mar 2021.

Vancouver:

Kautz M. Implementing a Residency Program to Affect Float Pool Nurse Retention Rates. [Internet] [Thesis]. Regis University; 2017. [cited 2021 Mar 08]. Available from: http://epublications.regis.edu/theses/825.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kautz M. Implementing a Residency Program to Affect Float Pool Nurse Retention Rates. [Thesis]. Regis University; 2017. Available from: http://epublications.regis.edu/theses/825

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

17. Adams Robertson, Elwanda F. Standardized Testing and Remediation to Improve NCLEX-RN Pass Rates in an Associate.

Degree: 2017, Regis University

URL: http://epublications.regis.edu/theses/827

► First time pass rate success on the National Council Licensure Examination for Registered Nurses (NCLEX-RN) is an expectation for all nursing programs. Nursing faculty… (more)

Subjects/Keywords: DNP Capstone Project; Standardized Testing; NCLEX-RN; Remediation; Retention

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APA (6^th Edition):

Adams Robertson, E. F. (2017). Standardized Testing and Remediation to Improve NCLEX-RN Pass Rates in an Associate. (Thesis). Regis University. Retrieved from http://epublications.regis.edu/theses/827

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Adams Robertson, Elwanda F. “Standardized Testing and Remediation to Improve NCLEX-RN Pass Rates in an Associate.” 2017. Thesis, Regis University. Accessed March 08, 2021. http://epublications.regis.edu/theses/827.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Adams Robertson, Elwanda F. “Standardized Testing and Remediation to Improve NCLEX-RN Pass Rates in an Associate.” 2017. Web. 08 Mar 2021.

Vancouver:

Adams Robertson EF. Standardized Testing and Remediation to Improve NCLEX-RN Pass Rates in an Associate. [Internet] [Thesis]. Regis University; 2017. [cited 2021 Mar 08]. Available from: http://epublications.regis.edu/theses/827.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Adams Robertson EF. Standardized Testing and Remediation to Improve NCLEX-RN Pass Rates in an Associate. [Thesis]. Regis University; 2017. Available from: http://epublications.regis.edu/theses/827

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

18. Flatekval, Anne Marie. The Implementation of a Leadership Development Program and Its Impact on Nurse Managers Self-Reported Competency Levels.

Degree: 2017, Regis University

URL: http://epublications.regis.edu/theses/829

► The nurse manager has a crucial role in healthcare organizations. The responsibilities include ensuring the care provided to patients is safe, caring, effective, and… (more)

Subjects/Keywords: DNP Project; Leadership development; Nurse manager competency levels

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APA (6^th Edition):

Flatekval, A. M. (2017). The Implementation of a Leadership Development Program and Its Impact on Nurse Managers Self-Reported Competency Levels. (Thesis). Regis University. Retrieved from http://epublications.regis.edu/theses/829

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Flatekval, Anne Marie. “The Implementation of a Leadership Development Program and Its Impact on Nurse Managers Self-Reported Competency Levels.” 2017. Thesis, Regis University. Accessed March 08, 2021. http://epublications.regis.edu/theses/829.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Flatekval, Anne Marie. “The Implementation of a Leadership Development Program and Its Impact on Nurse Managers Self-Reported Competency Levels.” 2017. Web. 08 Mar 2021.

Vancouver:

Flatekval AM. The Implementation of a Leadership Development Program and Its Impact on Nurse Managers Self-Reported Competency Levels. [Internet] [Thesis]. Regis University; 2017. [cited 2021 Mar 08]. Available from: http://epublications.regis.edu/theses/829.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Flatekval AM. The Implementation of a Leadership Development Program and Its Impact on Nurse Managers Self-Reported Competency Levels. [Thesis]. Regis University; 2017. Available from: http://epublications.regis.edu/theses/829

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

19. Duvall, Gordon E. Medical Home Access Effect on Recidivism Rates of the Inner City Juvenile Detention Population.

Degree: 2018, Regis University

URL: https://epublications.regis.edu/theses/903

► This is an overview of the DNP project that was used for the writer’s Doctor of Nursing Practice degree. The project focus is the… (more)

Subjects/Keywords: juvenile detention; recidivism; medical home; DNP capstone project

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APA (6^th Edition):

Duvall, G. E. (2018). Medical Home Access Effect on Recidivism Rates of the Inner City Juvenile Detention Population. (Thesis). Regis University. Retrieved from https://epublications.regis.edu/theses/903

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Duvall, Gordon E. “Medical Home Access Effect on Recidivism Rates of the Inner City Juvenile Detention Population.” 2018. Thesis, Regis University. Accessed March 08, 2021. https://epublications.regis.edu/theses/903.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Duvall, Gordon E. “Medical Home Access Effect on Recidivism Rates of the Inner City Juvenile Detention Population.” 2018. Web. 08 Mar 2021.

Vancouver:

Duvall GE. Medical Home Access Effect on Recidivism Rates of the Inner City Juvenile Detention Population. [Internet] [Thesis]. Regis University; 2018. [cited 2021 Mar 08]. Available from: https://epublications.regis.edu/theses/903.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Duvall GE. Medical Home Access Effect on Recidivism Rates of the Inner City Juvenile Detention Population. [Thesis]. Regis University; 2018. Available from: https://epublications.regis.edu/theses/903

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

20. Burch, Alice M. Rural School Nursing in Colorado: New Perspectives.

Degree: 2018, Regis University

URL: https://epublications.regis.edu/theses/904

► Rural school nurses face the challenge of practicing nursing care in an environment that is not built around health care. They are often the… (more)

Subjects/Keywords: DNP Capstone Project; Poverty and Homelessness; Communication Challenges; Unmet Students’ Needs

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APA (6^th Edition):

Burch, A. M. (2018). Rural School Nursing in Colorado: New Perspectives. (Thesis). Regis University. Retrieved from https://epublications.regis.edu/theses/904

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Burch, Alice M. “Rural School Nursing in Colorado: New Perspectives.” 2018. Thesis, Regis University. Accessed March 08, 2021. https://epublications.regis.edu/theses/904.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Burch, Alice M. “Rural School Nursing in Colorado: New Perspectives.” 2018. Web. 08 Mar 2021.

Vancouver:

Burch AM. Rural School Nursing in Colorado: New Perspectives. [Internet] [Thesis]. Regis University; 2018. [cited 2021 Mar 08]. Available from: https://epublications.regis.edu/theses/904.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Burch AM. Rural School Nursing in Colorado: New Perspectives. [Thesis]. Regis University; 2018. Available from: https://epublications.regis.edu/theses/904

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

21. Bello, Rochelle D. Enhancing Environmental Staff Cleaning Process and Adenosine Triphosphate (ATP).

Degree: 2019, Regis University

URL: https://epublications.regis.edu/theses/939

► Clostridium difficile (C. difficile) has become the most common microbial cause of healthcareassociated infections (HAI) in U.S. hospitals and costs billions of dollars each… (more)

Subjects/Keywords: DNP project; Healthcare-associated infections; Preventing C. difficile

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APA (6^th Edition):

Bello, R. D. (2019). Enhancing Environmental Staff Cleaning Process and Adenosine Triphosphate (ATP). (Thesis). Regis University. Retrieved from https://epublications.regis.edu/theses/939

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Bello, Rochelle D. “Enhancing Environmental Staff Cleaning Process and Adenosine Triphosphate (ATP).” 2019. Thesis, Regis University. Accessed March 08, 2021. https://epublications.regis.edu/theses/939.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Bello, Rochelle D. “Enhancing Environmental Staff Cleaning Process and Adenosine Triphosphate (ATP).” 2019. Web. 08 Mar 2021.

Vancouver:

Bello RD. Enhancing Environmental Staff Cleaning Process and Adenosine Triphosphate (ATP). [Internet] [Thesis]. Regis University; 2019. [cited 2021 Mar 08]. Available from: https://epublications.regis.edu/theses/939.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bello RD. Enhancing Environmental Staff Cleaning Process and Adenosine Triphosphate (ATP). [Thesis]. Regis University; 2019. Available from: https://epublications.regis.edu/theses/939

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

22. Bilbrew, Emerald. Do Nurses Credit magnet Status Forces as a Reason for Increased Job Satisfaction?.

Degree: 2017, Regis University

URL: https://epublications.regis.edu/theses/832

► This study examined the relationship between Magnet status forces and job satisfaction. A survey was administered to compare the job satisfaction factors to Magnet… (more)

Subjects/Keywords: job satisfaction; nurse retention; Magnet status; DNP project; survey opinions

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APA (6^th Edition):

Bilbrew, E. (2017). Do Nurses Credit magnet Status Forces as a Reason for Increased Job Satisfaction?. (Thesis). Regis University. Retrieved from https://epublications.regis.edu/theses/832

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Bilbrew, Emerald. “Do Nurses Credit magnet Status Forces as a Reason for Increased Job Satisfaction?.” 2017. Thesis, Regis University. Accessed March 08, 2021. https://epublications.regis.edu/theses/832.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Bilbrew, Emerald. “Do Nurses Credit magnet Status Forces as a Reason for Increased Job Satisfaction?.” 2017. Web. 08 Mar 2021.

Vancouver:

Bilbrew E. Do Nurses Credit magnet Status Forces as a Reason for Increased Job Satisfaction?. [Internet] [Thesis]. Regis University; 2017. [cited 2021 Mar 08]. Available from: https://epublications.regis.edu/theses/832.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bilbrew E. Do Nurses Credit magnet Status Forces as a Reason for Increased Job Satisfaction?. [Thesis]. Regis University; 2017. Available from: https://epublications.regis.edu/theses/832

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

23. Smith, Melissa J. Step Model for Managing Chronic, Non-Malignant Pain in Primary Care.

Degree: 2019, Regis University

URL: https://epublications.regis.edu/theses/921

► Oftentimes, primary care providers lack the knowledge, confidence, and time to monitor chronic pain patients closely resulting in possible inappropriate prescribing of opioids. Purpose:… (more)

Subjects/Keywords: DNP project; step model; chronic pain; primary care; CDC guidelines

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APA (6^th Edition):

Smith, M. J. (2019). Step Model for Managing Chronic, Non-Malignant Pain in Primary Care. (Thesis). Regis University. Retrieved from https://epublications.regis.edu/theses/921

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Smith, Melissa J. “Step Model for Managing Chronic, Non-Malignant Pain in Primary Care.” 2019. Thesis, Regis University. Accessed March 08, 2021. https://epublications.regis.edu/theses/921.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Smith, Melissa J. “Step Model for Managing Chronic, Non-Malignant Pain in Primary Care.” 2019. Web. 08 Mar 2021.

Vancouver:

Smith MJ. Step Model for Managing Chronic, Non-Malignant Pain in Primary Care. [Internet] [Thesis]. Regis University; 2019. [cited 2021 Mar 08]. Available from: https://epublications.regis.edu/theses/921.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Smith MJ. Step Model for Managing Chronic, Non-Malignant Pain in Primary Care. [Thesis]. Regis University; 2019. Available from: https://epublications.regis.edu/theses/921

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

24. Tisdale, Kelly M. Nursing Educators Need Our Help.

Degree: 2018, Regis University

URL: https://epublications.regis.edu/theses/889

► There is a current demand for nurses and nursing faculty. Nursing faculty are necessary in order to meet the need for registered nurses in… (more)

Subjects/Keywords: DNP Capstone Project; Nursing Faculty; Orientation; Faculty Retention

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APA (6^th Edition):

Tisdale, K. M. (2018). Nursing Educators Need Our Help. (Thesis). Regis University. Retrieved from https://epublications.regis.edu/theses/889

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Tisdale, Kelly M. “Nursing Educators Need Our Help.” 2018. Thesis, Regis University. Accessed March 08, 2021. https://epublications.regis.edu/theses/889.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Tisdale, Kelly M. “Nursing Educators Need Our Help.” 2018. Web. 08 Mar 2021.

Vancouver:

Tisdale KM. Nursing Educators Need Our Help. [Internet] [Thesis]. Regis University; 2018. [cited 2021 Mar 08]. Available from: https://epublications.regis.edu/theses/889.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Tisdale KM. Nursing Educators Need Our Help. [Thesis]. Regis University; 2018. Available from: https://epublications.regis.edu/theses/889

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

25. O'Meara, Meghan. Identifying Perceived Barriers to Communication and Coordination of Care of the Liver Transplant Recipient.

Degree: 2018, Regis University

URL: https://epublications.regis.edu/theses/873

► Abstract Communication is essential between and among all members of the health care team to provide coordinated care that is effective, efficient, cost sensitive,… (more)

Subjects/Keywords: DNP project; liver transplant; communication; coordination of care

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APA (6^th Edition):

O'Meara, M. (2018). Identifying Perceived Barriers to Communication and Coordination of Care of the Liver Transplant Recipient. (Thesis). Regis University. Retrieved from https://epublications.regis.edu/theses/873

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

O'Meara, Meghan. “Identifying Perceived Barriers to Communication and Coordination of Care of the Liver Transplant Recipient.” 2018. Thesis, Regis University. Accessed March 08, 2021. https://epublications.regis.edu/theses/873.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

O'Meara, Meghan. “Identifying Perceived Barriers to Communication and Coordination of Care of the Liver Transplant Recipient.” 2018. Web. 08 Mar 2021.

Vancouver:

O'Meara M. Identifying Perceived Barriers to Communication and Coordination of Care of the Liver Transplant Recipient. [Internet] [Thesis]. Regis University; 2018. [cited 2021 Mar 08]. Available from: https://epublications.regis.edu/theses/873.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

O'Meara M. Identifying Perceived Barriers to Communication and Coordination of Care of the Liver Transplant Recipient. [Thesis]. Regis University; 2018. Available from: https://epublications.regis.edu/theses/873

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

26. Robilotto, Tracey. The Impact of High-Fidelity Simulation Practice on the Perceived Confidence of Experienced ICU Nurses.

Degree: 2019, Regis University

URL: https://epublications.regis.edu/theses/922

► the pre-evaluations however, not all scores improved between the three scenarios. In fact, four of the nine total scores collected remained the same. In… (more)

Subjects/Keywords: Professional Staff Development; Simulation; DNP Project; Nurse Confidence; Self- Perceptions

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APA (6^th Edition):

Robilotto, T. (2019). The Impact of High-Fidelity Simulation Practice on the Perceived Confidence of Experienced ICU Nurses. (Thesis). Regis University. Retrieved from https://epublications.regis.edu/theses/922

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Robilotto, Tracey. “The Impact of High-Fidelity Simulation Practice on the Perceived Confidence of Experienced ICU Nurses.” 2019. Thesis, Regis University. Accessed March 08, 2021. https://epublications.regis.edu/theses/922.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Robilotto, Tracey. “The Impact of High-Fidelity Simulation Practice on the Perceived Confidence of Experienced ICU Nurses.” 2019. Web. 08 Mar 2021.

Vancouver:

Robilotto T. The Impact of High-Fidelity Simulation Practice on the Perceived Confidence of Experienced ICU Nurses. [Internet] [Thesis]. Regis University; 2019. [cited 2021 Mar 08]. Available from: https://epublications.regis.edu/theses/922.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Robilotto T. The Impact of High-Fidelity Simulation Practice on the Perceived Confidence of Experienced ICU Nurses. [Thesis]. Regis University; 2019. Available from: https://epublications.regis.edu/theses/922

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

27. Wolz, Kathleen M. Building Faculty Competence and Self-Efficacy for Using Z Space Virtual Reality (VR) Software in the Classroom.

Degree: 2019, Regis University

URL: https://epublications.regis.edu/theses/920

► The environments of teaching and learning are changing as educational needs and technology advancements evolve. One of the newest technologies gaining momentum in healthcare… (more)

Subjects/Keywords: DNP Capstone Project; Virtual Reality; Technology; Nurse Educators

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APA (6^th Edition):

Wolz, K. M. (2019). Building Faculty Competence and Self-Efficacy for Using Z Space Virtual Reality (VR) Software in the Classroom. (Thesis). Regis University. Retrieved from https://epublications.regis.edu/theses/920

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Wolz, Kathleen M. “Building Faculty Competence and Self-Efficacy for Using Z Space Virtual Reality (VR) Software in the Classroom.” 2019. Thesis, Regis University. Accessed March 08, 2021. https://epublications.regis.edu/theses/920.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Wolz, Kathleen M. “Building Faculty Competence and Self-Efficacy for Using Z Space Virtual Reality (VR) Software in the Classroom.” 2019. Web. 08 Mar 2021.

Vancouver:

Wolz KM. Building Faculty Competence and Self-Efficacy for Using Z Space Virtual Reality (VR) Software in the Classroom. [Internet] [Thesis]. Regis University; 2019. [cited 2021 Mar 08]. Available from: https://epublications.regis.edu/theses/920.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Wolz KM. Building Faculty Competence and Self-Efficacy for Using Z Space Virtual Reality (VR) Software in the Classroom. [Thesis]. Regis University; 2019. Available from: https://epublications.regis.edu/theses/920

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

28. Santiago, Julio. The Impact of an Online Educational Course on Vascular Nurses’ Knowledge, Self-Confidence and Competence.

Degree: 2019, Regis University

URL: https://epublications.regis.edu/theses/943

► In the United States, approximately 8 to 10% of patients admitted to an acute care facility receive venous access. Nurses that specialize in vascular… (more)

Subjects/Keywords: DNP Project; PICC Insertion; Orientation Process; Standards of Practice

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APA (6^th Edition):

Santiago, J. (2019). The Impact of an Online Educational Course on Vascular Nurses’ Knowledge, Self-Confidence and Competence. (Thesis). Regis University. Retrieved from https://epublications.regis.edu/theses/943

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Santiago, Julio. “The Impact of an Online Educational Course on Vascular Nurses’ Knowledge, Self-Confidence and Competence.” 2019. Thesis, Regis University. Accessed March 08, 2021. https://epublications.regis.edu/theses/943.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Santiago, Julio. “The Impact of an Online Educational Course on Vascular Nurses’ Knowledge, Self-Confidence and Competence.” 2019. Web. 08 Mar 2021.

Vancouver:

Santiago J. The Impact of an Online Educational Course on Vascular Nurses’ Knowledge, Self-Confidence and Competence. [Internet] [Thesis]. Regis University; 2019. [cited 2021 Mar 08]. Available from: https://epublications.regis.edu/theses/943.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Santiago J. The Impact of an Online Educational Course on Vascular Nurses’ Knowledge, Self-Confidence and Competence. [Thesis]. Regis University; 2019. Available from: https://epublications.regis.edu/theses/943

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

29. Rivot, Angélique. Développement de l’IRM du poumon rehaussée par polarisation dynamique nucléaire : vers l’imagerie de la protéolyse : Lung MRI Development enhanced by dynamic nuclear polarization : toward proteolysis imaging.

Degree: Docteur es, Bioimagerie, 2019, Bordeaux

URL: http://www.theses.fr/2019BORD0274

►

Les maladies inflammatoires pulmonaires tels que la mucoviscidose et le BPCO, ont pour point commun un influx important de neutrophiles qui libèrent des protéases, responsables… (more)

▼

Les maladies inflammatoires pulmonaires tels que la mucoviscidose et le BPCO, ont pour point commun un influx important de neutrophiles qui libèrent des protéases, responsables des lésions tissulaires et de la perte progressive de fonction. À ce jour, il n'existe aucune méthode permettant d'évaluer l'activité des protéases dans le poumon in vivo. Une telle méthode permettrait un diagnostic précoce de tout déséquilibre protéase / inhibiteur bien avant la détection des lésions pulmonaires par des méthodes d'imagerie anatomique ainsi que l'évaluation de thérapies avec des inhibiteurs de protéases. L'IRM rehaussée par Polarisation dynamique nucléaire (PDN) est une approche possible pour révéler de telles activités enzymatiques en utilisant des nitroxydes spécifiques. Cependant, l’imagerie du poumon par IRM est encore aujourd’hui exigeante, en raison des propriétés intrinsèques à l'organe. Dans la nécessité d'obtenir du signal dans le poumon en IRM, une séquence radiale est souvent privilégiée. En effet, les trajectoires radiales bénéficient de nombreuses avantages comme leur faible sensibilité aux artefacts de mouvements ainsi que la possibilité de sous-échantillonner les acquisitions. Ainsi, l’objectif de cette thèse est de développer une séquence 3D à Temps d'Echo Ultra court sur un nouveau système IRM bas champ (0.2T) et de la comparer à une séquence robuste utilisant l'écho de spin. Les deux méthodes ont été implémentés au système afin d'obtenir des images en 3D en un temps d’acquisition limité. Après leur évaluation in vitro, leur utilisation in vivo chez la souris donnent accès à la biodistribution de nitroxydes dans le poumon, dont un substrat de l'élastase du neutrophile. L'IRM rehaussée a par ailleurs permis d'évaluer in vitro les activités enzymatiques de protéases à sérine dans le cas de poumons infectés.

Pulmonary inflammatory diseases such as cystic fibrosis and COPD, have in common a high influx of neutrophils that secrete proteases responsible for tissue injury and the progressive loss of lung function. To date there is no method able to assess lung enzyme activity in vivo. Such a method would allow an early diagnostic of any protease/inhibitor imbalance long before the detection of pulmonary lesions by anatomical imaging methods. Lungs function could thus be preserved with protease inhibitors. MRI enhanced by dynamic nuclear polarization (DNP) is an approach that reveal proteolytic activity through specific nitroxide. However, lung imaging by MRI is demanding, because of intrinsic properties. In order to obtain signal in the lung by MRI, a radial sequence imaging is often favorable. Indeed, radial trajectories benefit from various advantages like their low sensitivity to motion artefacts as well as the opportunity to highly undersample acquisitions. Thus the aim of this thesis was to develop a 3D Ultra Short Echo Time sequence on a new low field MRI system (0.2T). This sequence has been compared to a robust spin echo sequence. Both methods have been implemented in the system to obtain 3D images in a…

Advisors/Committee Members: Thiaudière, Éric (thesis director).

Subjects/Keywords: IRM; PDN; Protéolyse; Poumon; MRI; DNP; Proteolysis; Lung

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Rivot, A. (2019). Développement de l’IRM du poumon rehaussée par polarisation dynamique nucléaire : vers l’imagerie de la protéolyse : Lung MRI Development enhanced by dynamic nuclear polarization : toward proteolysis imaging. (Doctoral Dissertation). Bordeaux. Retrieved from http://www.theses.fr/2019BORD0274

Chicago Manual of Style (16^th Edition):

Rivot, Angélique. “Développement de l’IRM du poumon rehaussée par polarisation dynamique nucléaire : vers l’imagerie de la protéolyse : Lung MRI Development enhanced by dynamic nuclear polarization : toward proteolysis imaging.” 2019. Doctoral Dissertation, Bordeaux. Accessed March 08, 2021. http://www.theses.fr/2019BORD0274.

MLA Handbook (7^th Edition):

Rivot, Angélique. “Développement de l’IRM du poumon rehaussée par polarisation dynamique nucléaire : vers l’imagerie de la protéolyse : Lung MRI Development enhanced by dynamic nuclear polarization : toward proteolysis imaging.” 2019. Web. 08 Mar 2021.

Vancouver:

Rivot A. Développement de l’IRM du poumon rehaussée par polarisation dynamique nucléaire : vers l’imagerie de la protéolyse : Lung MRI Development enhanced by dynamic nuclear polarization : toward proteolysis imaging. [Internet] [Doctoral dissertation]. Bordeaux; 2019. [cited 2021 Mar 08]. Available from: http://www.theses.fr/2019BORD0274.

Council of Science Editors:

Rivot A. Développement de l’IRM du poumon rehaussée par polarisation dynamique nucléaire : vers l’imagerie de la protéolyse : Lung MRI Development enhanced by dynamic nuclear polarization : toward proteolysis imaging. [Doctoral Dissertation]. Bordeaux; 2019. Available from: http://www.theses.fr/2019BORD0274

Rutgers University

30. Elliott, Elaine. Childhood obesity: health and wellness promotion in the pre school population using parents and teachers as role models for healthy living.

Degree: Obesity in children – Prevention – Study and teaching, 2019, Rutgers University

URL: https://rucore.libraries.rutgers.edu/rutgers-lib/61278/

Subjects/Keywords: Post-Master's DNP Practice

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APA (6^th Edition):

Elliott, E. (2019). Childhood obesity: health and wellness promotion in the pre school population using parents and teachers as role models for healthy living. (Thesis). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/61278/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Elliott, Elaine. “Childhood obesity: health and wellness promotion in the pre school population using parents and teachers as role models for healthy living.” 2019. Thesis, Rutgers University. Accessed March 08, 2021. https://rucore.libraries.rutgers.edu/rutgers-lib/61278/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Elliott, Elaine. “Childhood obesity: health and wellness promotion in the pre school population using parents and teachers as role models for healthy living.” 2019. Web. 08 Mar 2021.

Vancouver:

Elliott E. Childhood obesity: health and wellness promotion in the pre school population using parents and teachers as role models for healthy living. [Internet] [Thesis]. Rutgers University; 2019. [cited 2021 Mar 08]. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/61278/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Elliott E. Childhood obesity: health and wellness promotion in the pre school population using parents and teachers as role models for healthy living. [Thesis]. Rutgers University; 2019. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/61278/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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Open Access Theses and Dissertations