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University of Colorado
1.
Hadigol, Mohammad.
Uncertainty Quantification of Coupled Problems with Applications to Lithium-ion Batteries.
Degree: PhD, Aerospace Engineering Sciences, 2016, University of Colorado
URL: https://scholar.colorado.edu/asen_gradetds/137
► This thesis includes three main parts that are concerned with the propagation of uncertainty across high-dimensional coupled problems with applications to Lithium-ion batteries (LIBs).…
(more)
▼ This thesis includes three main parts that are concerned with the propagation of uncertainty across high-dimensional
coupled problems with applications to Lithium-ion batteries (LIBs). In all three parts, spectral methods involving polynomial chaos expansions (PCEs) are employed to quantify the effects of propagating the input uncertainties across the system.
In the first part, a stochastic model reduction approach based on low-rank separated representations is proposed for the partitioned treatment of the uncertainty space in
coupled domain problems. Sequential construction of the sub-
domain solutions with respect to the stochastic dimensionality of each sub-
domain enabled by the classical FETI method drastically reduces the overall computational cost and provides a well suited framework for parallel computing. Two high-dimensional stochastic problems, a 2D elliptic PDE with random diffusion coefficient and a stochastic linear elasticity problem, have been considered to study the performance and accuracy of the proposed stochastic coupling approach.
A sampling-based UQ framework to study the effects of input uncertainties on the performance of LIBs using a full-order physics-based electrochemical model is presented in the second part. Developed based on sparse PCEs, the proposed UQ technique enables one to study the effects of LIB model uncertainties on the cell performance using a fairly small number of battery simulations. An LiC
6/LiCoO
2 cell with 19 random parameters has been considered to study the performance and accuracy of the proposed UQ approach. It was found that the battery discharge rate is a key factor affecting not only the performance variability of the cell, but also the determination of most important random inputs.
The third part provides a comprehensive review of the sampling techniques for the regression-based PCEs. Traditional sampling methods such Monte Carlo, Latin hypercube, quasi-Monte Carlo, optimal design of experiments, Gaussian quadratures as well as more recent techniques such as coherence-optimal and randomized quadratures are discussed. In addition, hybrid sampling methods referred to by the alphabetic coherence-optimal techniques which are a combination of the alphabetic optimality criteria and the coherence-optimal sampling method are proposed. It was observed that the alphabetic-coherence-optimal techniques outperform other sampling methods, specially when high-order PCEs are employed and/or the oversampling ratio is low.
Advisors/Committee Members: Alireza Doostan, Kurt Maute, Carlos Felippa, Se-Hee Lee, Brandon Jones.
Subjects/Keywords: Coupled Domain; High-dimensional; Lithium-ion Battery; Optimal Sampling; Polynomial Chaos Expansion; Uncertainty Quantification; Applied Mathematics; Engineering; Power and Energy
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APA (6th Edition):
Hadigol, M. (2016). Uncertainty Quantification of Coupled Problems with Applications to Lithium-ion Batteries. (Doctoral Dissertation). University of Colorado. Retrieved from https://scholar.colorado.edu/asen_gradetds/137
Chicago Manual of Style (16th Edition):
Hadigol, Mohammad. “Uncertainty Quantification of Coupled Problems with Applications to Lithium-ion Batteries.” 2016. Doctoral Dissertation, University of Colorado. Accessed March 07, 2021.
https://scholar.colorado.edu/asen_gradetds/137.
MLA Handbook (7th Edition):
Hadigol, Mohammad. “Uncertainty Quantification of Coupled Problems with Applications to Lithium-ion Batteries.” 2016. Web. 07 Mar 2021.
Vancouver:
Hadigol M. Uncertainty Quantification of Coupled Problems with Applications to Lithium-ion Batteries. [Internet] [Doctoral dissertation]. University of Colorado; 2016. [cited 2021 Mar 07].
Available from: https://scholar.colorado.edu/asen_gradetds/137.
Council of Science Editors:
Hadigol M. Uncertainty Quantification of Coupled Problems with Applications to Lithium-ion Batteries. [Doctoral Dissertation]. University of Colorado; 2016. Available from: https://scholar.colorado.edu/asen_gradetds/137

Florida International University
2.
Zhi, Xiaoduo.
Transcription-Coupled DNA Supercoiling in Escherichia Coli: Mechanisms and Biological Functions.
Degree: PhD, Chemistry, 2012, Florida International University
URL: https://digitalcommons.fiu.edu/etd/865
;
10.25148/etd.FI13042332
;
FI13042332
► Transcription by RNA polymerase can induce the formation of hypernegatively supercoiled DNA both in vivo and in vitro. This phenomenon has been explained by…
(more)
▼ Transcription by RNA polymerase can induce the formation of hypernegatively supercoiled DNA both
in vivo and
in vitro. This phenomenon has been explained by a “twin-supercoiled-domain” model of transcription where a positively supercoiled
domain is generated ahead of the RNA polymerase and a negatively supercoiled
domain behind it. In
E. coli cells, transcription-induced topological change of chromosomal DNA is expected to actively remodel chromosomal structure and greatly influence DNA transactions such as transcription, DNA replication, and recombination.
In this study, an IPTG-inducible, two-plasmid system was established to study transcription-
coupled DNA supercoiling (TCDS) in
E. coli topA strains. By performing topology assays, biological studies, and RT-PCR experiments, TCDS in
E. coli topA strains was found to be dependent on promoter strength. Expression of a membrane-insertion protein was not needed for strong promoters, although co-transcriptional synthesis of a polypeptide may be required. More importantly, it was demonstrated that the expression of a membrane-insertion
tet gene was not sufficient for the production of hypernegatively supercoiled DNA. These phenomenon can be explained by the “twin-supercoiled-domain” model of transcription where the friction force applied to
E. coli RNA polymerase plays a critical role in the generation of hypernegatively supercoiled DNA.
Additionally, in order to explore whether TCDS is able to greatly influence a
coupled DNA transaction, such as activating a divergently-
coupled promoter, an
in vivo system was set up to study TCDS and its effects on the supercoiling-sensitive
leu-500 promoter. The
leu-500 mutation is a single A-to-G point mutation in the -10 region of the promoter controlling the
leu operon, and the AT to GC mutation is expected to increase the energy barrier for the formation of a functional transcription open complex. Using luciferase assays and RT-PCR experiments, it was demonstrated that transient TCDS, “confined” within promoter regions, is responsible for activation of the
coupled transcription initiation of the
leu-500 promoter. Taken together, these results demonstrate that transcription is a major chromosomal remodeling force in
E. coli cells.
Advisors/Committee Members: Fenfei Leng, Lou W. Kim, Zhongwei Li, Joong-ho Moon, Kathleen Rein.
Subjects/Keywords: Transcription-coupled DNA supercoiling; Promoter strength; E. coli topA strains; Twin-supercoiled-domain model of transcription; Hypernegatively supercoiled DNA; Biochemistry
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Zhi, X. (2012). Transcription-Coupled DNA Supercoiling in Escherichia Coli: Mechanisms and Biological Functions. (Doctoral Dissertation). Florida International University. Retrieved from https://digitalcommons.fiu.edu/etd/865 ; 10.25148/etd.FI13042332 ; FI13042332
Chicago Manual of Style (16th Edition):
Zhi, Xiaoduo. “Transcription-Coupled DNA Supercoiling in Escherichia Coli: Mechanisms and Biological Functions.” 2012. Doctoral Dissertation, Florida International University. Accessed March 07, 2021.
https://digitalcommons.fiu.edu/etd/865 ; 10.25148/etd.FI13042332 ; FI13042332.
MLA Handbook (7th Edition):
Zhi, Xiaoduo. “Transcription-Coupled DNA Supercoiling in Escherichia Coli: Mechanisms and Biological Functions.” 2012. Web. 07 Mar 2021.
Vancouver:
Zhi X. Transcription-Coupled DNA Supercoiling in Escherichia Coli: Mechanisms and Biological Functions. [Internet] [Doctoral dissertation]. Florida International University; 2012. [cited 2021 Mar 07].
Available from: https://digitalcommons.fiu.edu/etd/865 ; 10.25148/etd.FI13042332 ; FI13042332.
Council of Science Editors:
Zhi X. Transcription-Coupled DNA Supercoiling in Escherichia Coli: Mechanisms and Biological Functions. [Doctoral Dissertation]. Florida International University; 2012. Available from: https://digitalcommons.fiu.edu/etd/865 ; 10.25148/etd.FI13042332 ; FI13042332

Delft University of Technology
3.
Clarenburg, Jimmy (author).
Efficient Design of Controlled Offshore Systems: A Holistic Approach.
Degree: 2019, Delft University of Technology
URL: http://resolver.tudelft.nl/uuid:67276027-7862-4a97-b5dc-0679108dee18
► Designing a controlled offshore system is a challenging process, the system dynamics are often nonlinear and subjected to loads that are random in nature. Furthermore,…
(more)
▼ Designing a controlled offshore system is a challenging process, the system dynamics are often nonlinear and subjected to loads that are random in nature. Furthermore, the proper description of the system’s dynamical behaviour involves knowledge pertaining to several fields. Unfortunately, at the design level, the process is often segregated between the different fields which are using highly advanced technology from their own discipline on overly simplified models relating to the other disciplines. This thesis focuses on creating a generic framework enabling appropriate modelling and analysis methods for controlled offshore systems considered as a whole. To create a virtual prototype of the system in a generic and modular way, the modelling is based on the formalism of multibody dynamics coupled to hydrodynamics. Generic methods for the linearisation of the system equations are introduced and implemented to enable analysis in both the time and frequency domains. The short term statistics are also provided in both domains, using spectral analysis in the frequency domain and time traces in the time domain. These different modules can be used to build the complete model, including control and study the system using classical techniques. Lastly, an approach to efficiently compute the workability plots is proposed as they are an important performance indicator of offshore systems. The considerable increase in computational speed gained through this approach opens the door for new types of insights such as parameter optimisation and sensitivity analysis. This holistic view of the system should allow engineers to take the right decision during the early phase of the design process by allowing them to explore different integrated design solutions and understand the influence of design parameters on the system’s workability. The example of a motion compensated gangway is used throughout the thesis to illustrate how the developed framework and methods can be used in practice.
Systems and Control
Advisors/Committee Members: van Wingerden, Jan-Willem (mentor), Delft University of Technology (degree granting institution).
Subjects/Keywords: Controlled Offshore Systems; Workability; Mixed Time-Frequency Domain Approach; Workability Sensitivity; Linearisation of Differential Algebraic Equations; Coupled Multibody and Hydrodynamics
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
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Manager
APA (6th Edition):
Clarenburg, J. (. (2019). Efficient Design of Controlled Offshore Systems: A Holistic Approach. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:67276027-7862-4a97-b5dc-0679108dee18
Chicago Manual of Style (16th Edition):
Clarenburg, Jimmy (author). “Efficient Design of Controlled Offshore Systems: A Holistic Approach.” 2019. Masters Thesis, Delft University of Technology. Accessed March 07, 2021.
http://resolver.tudelft.nl/uuid:67276027-7862-4a97-b5dc-0679108dee18.
MLA Handbook (7th Edition):
Clarenburg, Jimmy (author). “Efficient Design of Controlled Offshore Systems: A Holistic Approach.” 2019. Web. 07 Mar 2021.
Vancouver:
Clarenburg J(. Efficient Design of Controlled Offshore Systems: A Holistic Approach. [Internet] [Masters thesis]. Delft University of Technology; 2019. [cited 2021 Mar 07].
Available from: http://resolver.tudelft.nl/uuid:67276027-7862-4a97-b5dc-0679108dee18.
Council of Science Editors:
Clarenburg J(. Efficient Design of Controlled Offshore Systems: A Holistic Approach. [Masters Thesis]. Delft University of Technology; 2019. Available from: http://resolver.tudelft.nl/uuid:67276027-7862-4a97-b5dc-0679108dee18

University of Western Ontario
4.
Dunn, Henry A.
Regulation of CRFR1 and 5-HT2AR by PDZ Domain-Containing Proteins SAP97 and PSD-95.
Degree: 2014, University of Western Ontario
URL: https://ir.lib.uwo.ca/etd/2585
► Previous studies identified a crosstalk mechanism whereby CRFR1 sensitized 5-HT2AR-mediated signaling via interactions with PDZ domain-containing proteins: a mechanism that may underlie stress-induced anxiety and…
(more)
▼ Previous studies identified a crosstalk mechanism whereby CRFR1 sensitized 5-HT2AR-mediated signaling via interactions with PDZ domain-containing proteins: a mechanism that may underlie stress-induced anxiety and depression. This prompted an investigation into uncovering which PDZ domain-containing proteins could regulate the crosstalk between these two receptors, and how they could be regulated individually. In the current studies, a subset of PDZ domain-containing proteins were identified that may interact with CRFR1 and 5-HT2AR. The focus narrowed to two candidates previously implicated in psychiatric disease: SAP97 and PSD-95. We confirmed SAP97 and PSD-95 as interacting partners of CRFR1 in adult mouse cortex via co-immunoprecipitation. Both proteins exhibited functional regulation of CRFR1 by antagonizing CRFR1 endocytosis in HEK293 cells, measured by flow cytometry. Additionally, PSD-95 suppressed β-arrestin2 recruitment, thereby providing a potential mechanism for antagonizing endocytosis. Although neither SAP97 nor PSD-95 appeared to play a significant role in CRFR1-mediated cAMP signaling, endogenous SAP97 was integral for CRF-mediated ERK1/2 phosphorylation in HEK293 and AtT20 cells. Despite extensive sequence homology between SAP97 and PSD-95, PSD-95 did not appear to play a significant role in CRF-mediated ERK1/2 phosphorylation. Thus, we begin to understand subtle signaling biases between these two proteins. As PSD-95 was already documented to regulate 5-HT2AR, we investigated if SAP97 could play a role in regulating 5-HT2AR function. The interaction between SAP97 and 5-HT2AR was confirmed in adult mouse cortex. As was seen with CRFR1, SAP97 antagonized 5-HT2AR endocytosis. Although SAP97 did not appear to significantly modulate Gs-coupled signaling via CRFR1, the endogenous expression of SAP97 was integral for maximal Gq-coupled signaling via 5-HT2AR. Endogenous SAP97 was also required for ERK1/2 phosphorylation, and this regulatory role appears to be downstream of receptor interactions. Finally, we were unable to prevent the CRFR1-mediated sensitization of 5-HT2AR-mediated signaling by knocking down either SAP97 or PSD-95 using shRNA. Therefore, neither SAP97 nor PSD-95 appear to be exclusively involved in this heterologous crosstalk mechanism. Nevertheless, we have identified SAP97 and PSD-95 as novel regulators of CRFR1 function, and SAP97 as a novel regulator of 5-HT2AR function. These functional interactions may be targeted for the treatment of CRFR1- and 5-HT2AR-mediated mood disorders.
Subjects/Keywords: G protein-coupled receptors; PDZ domain-containing proteins; ERK signalling; receptor endocytosis; ßarrestin recruitment; mental health; Medical Molecular Biology
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Dunn, H. A. (2014). Regulation of CRFR1 and 5-HT2AR by PDZ Domain-Containing Proteins SAP97 and PSD-95. (Thesis). University of Western Ontario. Retrieved from https://ir.lib.uwo.ca/etd/2585
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Dunn, Henry A. “Regulation of CRFR1 and 5-HT2AR by PDZ Domain-Containing Proteins SAP97 and PSD-95.” 2014. Thesis, University of Western Ontario. Accessed March 07, 2021.
https://ir.lib.uwo.ca/etd/2585.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Dunn, Henry A. “Regulation of CRFR1 and 5-HT2AR by PDZ Domain-Containing Proteins SAP97 and PSD-95.” 2014. Web. 07 Mar 2021.
Vancouver:
Dunn HA. Regulation of CRFR1 and 5-HT2AR by PDZ Domain-Containing Proteins SAP97 and PSD-95. [Internet] [Thesis]. University of Western Ontario; 2014. [cited 2021 Mar 07].
Available from: https://ir.lib.uwo.ca/etd/2585.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Dunn HA. Regulation of CRFR1 and 5-HT2AR by PDZ Domain-Containing Proteins SAP97 and PSD-95. [Thesis]. University of Western Ontario; 2014. Available from: https://ir.lib.uwo.ca/etd/2585
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Lund
5.
Monge, Azahar.
Partitioned methods for time-dependent thermal
fluid-structure interaction.
Degree: 2018, University of Lund
URL: https://lup.lub.lu.se/record/a39adf53-8501-4ee1-9a2e-c9a86387be16
;
https://portal.research.lu.se/ws/files/49505455/Azahar_Monge_WEBB.pdf
► The efficient simulation of thermal interaction between fluids and structures is crucial in the design of many industrial products, e.g. turbine blades or rocket nozzles.…
(more)
▼ The efficient simulation of thermal interaction
between fluids and structures is crucial in the design of many
industrial products, e.g. turbine blades or rocket nozzles. The
main goal of this work is to present a high order time adaptive
multirate parallel partitioned coupled method for the efficient
numerical solution of two parabolic problems with strong jumps in
the material coefficients that can be further extended to thermal
fluid-structure interaction simulation. Our starting point was to
analyze the convergence rate of the Dirichlet-Neumann iteration,
which is one of the basic methods for simulating fluid-structure
problems, for the fully discretized unsteady transmission problem.
Specifically, we consider the coupling of two linear heat equations
on two identical non overlapping domains with jumps in the material
coefficients across these as a model for thermal fluid-structure
interaction. We provide an exact formula for the spectral radius of
the iteration matrix in 1D. We then show numerically that the 1D
result estimates the convergence rates of 2D examples and even of
nonlinear thermal fluid-structure interaction test cases with
unstructured grids.However, an important challenge when coupling
two different time-dependent problems is to increase
parallelization in time. We suggest a multirate Neumann-Neumann
waveform relaxation algorithm to solve two heterogeneous coupled
heat equations as an alternative to the Dirichlet-Neumann method.
In order to fix the mismatch produced by the multirate feature at
the space-time interface a linear interpolation is constructed.
Furthermore, we perform a one-dimensional convergence analysis for
the nonmultirate fully discretized heat equations to find the
optimal relaxation parameter in terms of the material coefficients,
the step size and the mesh resolution. This gives a very efficient
method which needs only two iterations. Numerical results confirm
the analysis and show that the 1D nonmultirate optimal relaxation
parameter is a very good estimator for the multirate 1D case and
even for multirate and nonmultirate 2D examples. Finally, we also
include in this work a time adaptive version of the multirate
Neumann-Neumann waveform relaxation method mentioned above.
Building a variable step size multirate scheme allows each of the
subsolvers to freely construct its own time grid independently of
each other. Therefore, the overall coupled method is more efficient
than the previous multirate version.
Subjects/Keywords: Natural Sciences; Engineering and Technology; thermal FSI; Conjugate heat transfer; Domain decomposition; Time adaptivity; Coupled problems; multirate
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Monge, A. (2018). Partitioned methods for time-dependent thermal
fluid-structure interaction. (Doctoral Dissertation). University of Lund. Retrieved from https://lup.lub.lu.se/record/a39adf53-8501-4ee1-9a2e-c9a86387be16 ; https://portal.research.lu.se/ws/files/49505455/Azahar_Monge_WEBB.pdf
Chicago Manual of Style (16th Edition):
Monge, Azahar. “Partitioned methods for time-dependent thermal
fluid-structure interaction.” 2018. Doctoral Dissertation, University of Lund. Accessed March 07, 2021.
https://lup.lub.lu.se/record/a39adf53-8501-4ee1-9a2e-c9a86387be16 ; https://portal.research.lu.se/ws/files/49505455/Azahar_Monge_WEBB.pdf.
MLA Handbook (7th Edition):
Monge, Azahar. “Partitioned methods for time-dependent thermal
fluid-structure interaction.” 2018. Web. 07 Mar 2021.
Vancouver:
Monge A. Partitioned methods for time-dependent thermal
fluid-structure interaction. [Internet] [Doctoral dissertation]. University of Lund; 2018. [cited 2021 Mar 07].
Available from: https://lup.lub.lu.se/record/a39adf53-8501-4ee1-9a2e-c9a86387be16 ; https://portal.research.lu.se/ws/files/49505455/Azahar_Monge_WEBB.pdf.
Council of Science Editors:
Monge A. Partitioned methods for time-dependent thermal
fluid-structure interaction. [Doctoral Dissertation]. University of Lund; 2018. Available from: https://lup.lub.lu.se/record/a39adf53-8501-4ee1-9a2e-c9a86387be16 ; https://portal.research.lu.se/ws/files/49505455/Azahar_Monge_WEBB.pdf

Loughborough University
6.
Matharu, Satpal.
Charge dynamics in coupled semiconductor superlattices.
Degree: PhD, 2015, Loughborough University
URL: http://hdl.handle.net/2134/17158
► In this thesis, we investigate the collective electron dynamics in single and coupled superlattice systems under the influence of a DC electric field. Firstly, we…
(more)
▼ In this thesis, we investigate the collective electron dynamics in single and coupled superlattice systems under the influence of a DC electric field. Firstly, we illustrate that Bloch oscillations suppress electron transport and the resulting charge domains form self-sustained current oscillations. Upon the application of a tilted magnetic field, stochastic web structures are shown to form in the phase space of the electron trajectory. This occurs only when the Bloch and cyclotron frequencies are commensurate allowing the electrons to demonstrate chaotic unbounded trajectories, leading to an increase in transport. The charge domain dynamics also present additional peaks during such resonances. The rapid changes in the dynamical states found is an example of non-KAM chaos. We show then the amplitude and frequency of current oscillations in a single superlattice can be controlled. Secondly, two models are designed to mutually couple two semiconductor superlattices by a common resistive load. We examine the effects of coupling strength and frequency detuning on the collective current dynamics. The devices are considered to be arranged together on a single substrate as well as on individual substrates. Large AC power is witnessed during anti-phase and in-phase synchronization between current oscillations. Finally, two superlattices are coupled through a resonance circuit incorporating single mode resonances from external influences in the circuit. In this system, chaotic current dynamics are induced with regions of chaos separating different regions of synchronization. High frequency oscillations with minimal phase difference cause the largest power generation. In all three coupling models high frequency components are found in the Fourier power spectra. The power generated in the coupled systems is found greater and at times more than double the power generated in the autonomous superlattice. Thus this thesis provides innovative methods of enhancing and controlling powerful high-frequency signals. This effectively gives manipulation over the intensity of the electromagnetic radiation produced by the superlattice.
Subjects/Keywords: 621.3815; Semiconductor; Superlattice; Charge; Dynamics; Bloch; Oscillation; Domain; Coupled; Frequency; Power; Electromagnetic; Magnetic; Field; Autonomous; Fourier; Synchronization; Terahertz; Radiation; Synchronisation
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Matharu, S. (2015). Charge dynamics in coupled semiconductor superlattices. (Doctoral Dissertation). Loughborough University. Retrieved from http://hdl.handle.net/2134/17158
Chicago Manual of Style (16th Edition):
Matharu, Satpal. “Charge dynamics in coupled semiconductor superlattices.” 2015. Doctoral Dissertation, Loughborough University. Accessed March 07, 2021.
http://hdl.handle.net/2134/17158.
MLA Handbook (7th Edition):
Matharu, Satpal. “Charge dynamics in coupled semiconductor superlattices.” 2015. Web. 07 Mar 2021.
Vancouver:
Matharu S. Charge dynamics in coupled semiconductor superlattices. [Internet] [Doctoral dissertation]. Loughborough University; 2015. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/2134/17158.
Council of Science Editors:
Matharu S. Charge dynamics in coupled semiconductor superlattices. [Doctoral Dissertation]. Loughborough University; 2015. Available from: http://hdl.handle.net/2134/17158

University of Manitoba
7.
Bhadra, Sharmistha.
Coupled Resonant Coil Sensors for Remote Passive Monitoring Applications.
Degree: Electrical and Computer Engineering, 2010, University of Manitoba
URL: http://hdl.handle.net/1993/4123
► The thesis describes development and application of coupled resonant coil sensors, which is of growing interest for remote monitoring applications. An interrogation technique, which improves…
(more)
▼ The thesis describes development and application of
coupled resonant coil sensors, which is of growing interest for remote monitoring applications. An interrogation technique, which improves the accuracy and interrogation range of
coupled resonant coil sensors, is introduced. The method uses time-
domain gating to produce measurements that are dominated by the response of the sensor coil and are immune to surrounding object interference. For application in structural health monitoring a low cost embeddable
coupled coil sensor, which is able to monitor the corrosion potential of reinforcement steel is presented. Results of an accelerated corrosion test using the sensor indicate that corrosion potential can be monitored with a resolution less than 10 mV and a sensitivity of 0.76 kHz/mV. The last part describes a
coupled-coil pH sensor based on pH electrode potential measurement. A linear response over a 4 to 10 pH dynamic range and 50 kHz/pH sensitivity are achieved with a 0.1 pH resolution and 30 s response time.
Advisors/Committee Members: Bridges, Greg (Electrical and Computer Engineering) (supervisor), Thomson, Douglas (Electrical and Computer Engineering) Svecova, Dagmar (Civil Engineering) (examiningcommittee).
Subjects/Keywords: accelerated corrosion test; corrosion potential; coupled coil; passive; reinforcement steel; resonant frequency; varactor; wireless; quality factor; pH; interrogator; time-domain gating; pH combination electrode; interrogation distance
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Bhadra, S. (2010). Coupled Resonant Coil Sensors for Remote Passive Monitoring Applications. (Masters Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/4123
Chicago Manual of Style (16th Edition):
Bhadra, Sharmistha. “Coupled Resonant Coil Sensors for Remote Passive Monitoring Applications.” 2010. Masters Thesis, University of Manitoba. Accessed March 07, 2021.
http://hdl.handle.net/1993/4123.
MLA Handbook (7th Edition):
Bhadra, Sharmistha. “Coupled Resonant Coil Sensors for Remote Passive Monitoring Applications.” 2010. Web. 07 Mar 2021.
Vancouver:
Bhadra S. Coupled Resonant Coil Sensors for Remote Passive Monitoring Applications. [Internet] [Masters thesis]. University of Manitoba; 2010. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/1993/4123.
Council of Science Editors:
Bhadra S. Coupled Resonant Coil Sensors for Remote Passive Monitoring Applications. [Masters Thesis]. University of Manitoba; 2010. Available from: http://hdl.handle.net/1993/4123

Virginia Tech
8.
Sutton, Daniel.
Improved Reduced Order Modeling Strategies for Coupled and Parametric Systems.
Degree: MS, Mechanical Engineering, 2005, Virginia Tech
URL: http://hdl.handle.net/10919/34639
► This thesis uses Proper Orthogonal Decomposition to model parametric and coupled systems. First, Proper Orthogonal Decomposition and its properties are introduced as well as how…
(more)
▼ This thesis uses Proper Orthogonal Decomposition to model parametric and
coupled systems. First, Proper Orthogonal Decomposition and its properties are introduced as well as how to numerically compute the decomposition. Next, a test case was used to show how well POD can be used to simulate and control a system. Finally, techniques for modeling a parametric system over a given range and a
coupled system split into subdomains were explored, as well as numerical results.
Advisors/Committee Members: Robertshaw, Harry H. (committee member), Borggaard, Jeffrey T. (committeecochair), Inman, Daniel J. (committeecochair).
Subjects/Keywords: Reduced Order Modeling; Coupled Systems; Domain Decomposition; Proper Orthogonal Decomposition; Feedback Control
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Sutton, D. (2005). Improved Reduced Order Modeling Strategies for Coupled and Parametric Systems. (Masters Thesis). Virginia Tech. Retrieved from http://hdl.handle.net/10919/34639
Chicago Manual of Style (16th Edition):
Sutton, Daniel. “Improved Reduced Order Modeling Strategies for Coupled and Parametric Systems.” 2005. Masters Thesis, Virginia Tech. Accessed March 07, 2021.
http://hdl.handle.net/10919/34639.
MLA Handbook (7th Edition):
Sutton, Daniel. “Improved Reduced Order Modeling Strategies for Coupled and Parametric Systems.” 2005. Web. 07 Mar 2021.
Vancouver:
Sutton D. Improved Reduced Order Modeling Strategies for Coupled and Parametric Systems. [Internet] [Masters thesis]. Virginia Tech; 2005. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/10919/34639.
Council of Science Editors:
Sutton D. Improved Reduced Order Modeling Strategies for Coupled and Parametric Systems. [Masters Thesis]. Virginia Tech; 2005. Available from: http://hdl.handle.net/10919/34639
9.
Rampazzo, Fabiano Pinheiro.
Estudo de viabilidade do sistema de ancoragem de uma unidade flutuante de produção e armazenamento \"FPSO\" acoplada a um sistema de completação seca \"TLWP\".
Degree: Mestrado, Engenharia Naval e Oceânica, 2011, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/3/3135/tde-13072011-103539/
;
► A produção de petróleo e gás em campos brasileiros é cada vez mais proveniente de regiões com águas profundas e situadas longe da costa, chegando…
(more)
▼ A produção de petróleo e gás em campos brasileiros é cada vez mais proveniente de regiões com águas profundas e situadas longe da costa, chegando a distâncias de mais de 100 km, como, por exemplo, na Bacia de Campos ou de Santos. Devido à falta de infra-estrutura e às características do petróleo desses campos, a cadeia de abastecimento e o sistema de exportação da produção possuem grande importância para a indústria offshore. Uma maneira usual para a exportação da produção é através de dutos submarinos, onde o óleo e/ou a gás flui das plataformas diretamente para o continente. Com esta infra-estrutura é possível a utilização de sistemas de produção sem capacidade de armazenamento e, conseqüentemente, torna-se desnecessário o uso de navios para o alívio da produção. No entanto, devido à qualidade do óleo e às distâncias entre os poços e a costa em alguns campos brasileiros, a utilização dos oleodutos mostra-se uma solução pouco viável. Por este motivo, é bastante comum o uso de FPSOs ou semi-submersíveis conectadas a sistemas auxiliares, como o FSO (Floating Storage and Offloading). Nas plataformas, outra característica importante e desejada é tornar viável o uso de um sistema de completação seca (árvore de Natal acima da linha dágua) com o objetivo de diminuir, significativamente, os custos operacionais envolvidos. Esse tipo de completação é utilizado, com excelência, por unidade do tipo TLWP ou Spar, devido ao baixo nível dos movimentos e acelerações observadas nestas plataformas. Entretanto, as condições ambientais severas amplificam as dificuldades para encontrar um sistema com grande capacidade de armazenamento e que permita o uso de completação seca. Neste contexto, pesquisadores e engenheiros estão sendo obrigados a desenvolver novos conceitos capazes de atender a essa demanda. Desta forma, uma nova solução, considerando um FPSO e uma TLWP operando a uma curta distância e trabalhando de forma acoplada com a conexão garantida por cabos sintéticos vem sendo estudada. Essencialmente, o grande atrativo deste conceito é o fato de que toda a produção e o armazenamento são concentrados no FPSO e a TLWP é responsável pela perfuração e extração dos hidrocarbonetos através de risers verticais. Assim o sistema trabalhando de forma conjunta possui capacidade de armazenamento e permite o uso da completação seca. Nesta dissertação, foi realizado um estudo sobre a evolução deste novo conceito, dividido em três fases. A primeira focada no dimensionamento do sistema de conexão e ancoragem das unidades e em uma investigação da interação hidrodinâmica entre as unidades de forma a mostrar a viabilidade do sistema. A segunda fase, focada na validação dos resultados por meio da comparação com os testes realizados no modelo em escala do NMRI (National Maritime Research Institute - Japão). Finalmente, a terceira fase, com foco no redimensionamento do sistema de amarração e no sistema de conexão, com base nos resultados obtidos na segunda fase.
The oil and gas production in Brazilian fields are commonly found in deep water and…
Advisors/Committee Members: Nishimoto, Kazuo.
Subjects/Keywords: Análise dinâmica acoplada; Análise no domínio do tempo; Completação seca; Coupled system; Dry tree completion; FPSO-TLWP; FPSO-TLWP; Fully coupled analysis; Numerical Offshore Tank (TPN); Sistema de produção acoplada; Tanque de Provas Numérico (TPN); Time domain simulation
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
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APA (6th Edition):
Rampazzo, F. P. (2011). Estudo de viabilidade do sistema de ancoragem de uma unidade flutuante de produção e armazenamento \"FPSO\" acoplada a um sistema de completação seca \"TLWP\". (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/3/3135/tde-13072011-103539/ ;
Chicago Manual of Style (16th Edition):
Rampazzo, Fabiano Pinheiro. “Estudo de viabilidade do sistema de ancoragem de uma unidade flutuante de produção e armazenamento \"FPSO\" acoplada a um sistema de completação seca \"TLWP\".” 2011. Masters Thesis, University of São Paulo. Accessed March 07, 2021.
http://www.teses.usp.br/teses/disponiveis/3/3135/tde-13072011-103539/ ;.
MLA Handbook (7th Edition):
Rampazzo, Fabiano Pinheiro. “Estudo de viabilidade do sistema de ancoragem de uma unidade flutuante de produção e armazenamento \"FPSO\" acoplada a um sistema de completação seca \"TLWP\".” 2011. Web. 07 Mar 2021.
Vancouver:
Rampazzo FP. Estudo de viabilidade do sistema de ancoragem de uma unidade flutuante de produção e armazenamento \"FPSO\" acoplada a um sistema de completação seca \"TLWP\". [Internet] [Masters thesis]. University of São Paulo; 2011. [cited 2021 Mar 07].
Available from: http://www.teses.usp.br/teses/disponiveis/3/3135/tde-13072011-103539/ ;.
Council of Science Editors:
Rampazzo FP. Estudo de viabilidade do sistema de ancoragem de uma unidade flutuante de produção e armazenamento \"FPSO\" acoplada a um sistema de completação seca \"TLWP\". [Masters Thesis]. University of São Paulo; 2011. Available from: http://www.teses.usp.br/teses/disponiveis/3/3135/tde-13072011-103539/ ;
10.
Li, Ji.
Modèle dans le domaine temporel et la validation expérimentale d’un scanner ultrasonore à ondes de surface sans contact : Time domain model and experimental validation of the non-contact surface wave ultrasonic scanner.
Degree: Docteur es, Micro et Nano Technologies, Acoustique et Télécommunications, 2017, Ecole centrale de Lille
URL: http://www.theses.fr/2017ECLI0026
► Ce travail de recherche propose l’algorithme de calcul pour la modélisation d’un scanner ultrasonore sans contact à ondes de surface. L’approche proposée permet de prendre…
(more)
▼ Ce travail de recherche propose l’algorithme de calcul pour la modélisation d’un scanner ultrasonore sans contact à ondes de surface. L’approche proposée permet de prendre en compte l’ouverture finie du récepteur, l’atténuation d’air et la réponse électrique he de l’ensemble émetteur-récepteur. Le milieu avec l’atténuation (air et milieu testé) est modélisé dans le domaine temporel à l’aide de la fonction de Green causale permettant la caractérisation large bande. Le réponse he est déterminée de manière expérimentale en utilisant la procédure spatialement développée, incluant la déconvolution des effets d’atténuation. Le modèle est implémenté numériquement en utilisant l’approche de la Représentation Discrète et les résultats obtenus sont validés expérimentalement. La technique chirp est utilisée afin d’améliorer le rapport signal/bruit. Il est démontré que lorsque l’atténuation dans l’air, la dimension de récepteur et la réponse he reconstituée avec précision sont correctement pris en compte, la réponse impulsionnelle du système peut être prédite avec l’erreur de 2-5 %. L’introduction de la taille du récepteur est essentielle pour la prédiction dans le champ proche. Le temps de calcul obtenu est considérablement plus court que le temps nécessaire pour les méthodes FEM. A l’aide de ce modèle l’influence des réglages du scanner est étudiée. Les résultats obtenus permettent de formuler des recommandations pour les réglages optimaux
In this research the time-domain model for the prediction of an acoustic field in an air-coupled, non-contact, surface wave scanner is proposed. The model takes into account the finite size of the aperture receiver, attenuation in air, and the electric response he of the emitter-receiver set he. The attenuation is characterized by a causal time-domain Green’s function, allowing the wideband attenuation of a lossy medium (air and solid tested sample) obeying the power law to be modelled. The response he is recovered experimentally using an original especially developed procedure which includes the deconvolution of air absorption effects. The model is implemented numerically using a Discrete Representation approach and validated experimentally. In order to improve the signal to noise ratio the chirp technique is used. It is shown that when the attenuation in air, the receiver size, and the accurately recovered response he, are correctly taken into account, the model allows the system’s impulse response to be very accurately predicted, with errors ranging between 2-5%. Inclusion of the size of the receiver dimension in the model appears to be crucial to the accuracy of the near field predictions. The obtained computation efficiency is much better that efficiency of FEM methods. The influence of typical user defined settings has been investigated. The obtained conclusions will be used as the recommendations for further use
Advisors/Committee Members: Piwakowski, Bogdan (thesis director).
Subjects/Keywords: Transducteurs sans contact; Non-contact NDT; Onde de surface; Fonction de Green dans le domaine temporel; Réponse spatiale; Atténuation; Causalité; Dispersion de vitesse; Intégrale de Rayleigh; Méthode de la représentation discrète; Mesures automatiques; Air-coupled transducers; Air coupled NDT; Surface Wave; Time domain Grenn's function; Spatial pulse reponse; Attenuation; Causality; Velocity dispersion; Rayleigh's integral; Discrete representation approach; Automated scanning
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Li, J. (2017). Modèle dans le domaine temporel et la validation expérimentale d’un scanner ultrasonore à ondes de surface sans contact : Time domain model and experimental validation of the non-contact surface wave ultrasonic scanner. (Doctoral Dissertation). Ecole centrale de Lille. Retrieved from http://www.theses.fr/2017ECLI0026
Chicago Manual of Style (16th Edition):
Li, Ji. “Modèle dans le domaine temporel et la validation expérimentale d’un scanner ultrasonore à ondes de surface sans contact : Time domain model and experimental validation of the non-contact surface wave ultrasonic scanner.” 2017. Doctoral Dissertation, Ecole centrale de Lille. Accessed March 07, 2021.
http://www.theses.fr/2017ECLI0026.
MLA Handbook (7th Edition):
Li, Ji. “Modèle dans le domaine temporel et la validation expérimentale d’un scanner ultrasonore à ondes de surface sans contact : Time domain model and experimental validation of the non-contact surface wave ultrasonic scanner.” 2017. Web. 07 Mar 2021.
Vancouver:
Li J. Modèle dans le domaine temporel et la validation expérimentale d’un scanner ultrasonore à ondes de surface sans contact : Time domain model and experimental validation of the non-contact surface wave ultrasonic scanner. [Internet] [Doctoral dissertation]. Ecole centrale de Lille; 2017. [cited 2021 Mar 07].
Available from: http://www.theses.fr/2017ECLI0026.
Council of Science Editors:
Li J. Modèle dans le domaine temporel et la validation expérimentale d’un scanner ultrasonore à ondes de surface sans contact : Time domain model and experimental validation of the non-contact surface wave ultrasonic scanner. [Doctoral Dissertation]. Ecole centrale de Lille; 2017. Available from: http://www.theses.fr/2017ECLI0026

Texas A&M University
11.
Jeong, Jaehoon.
Analytical time domain electromagnetic field propagators and closed-form solutions for transmission lines.
Degree: PhD, Electrical Engineering, 2009, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-1105
► An analytical solution for the coupled telegrapher’s equations in terms of the voltage and current on a homogeneous lossy transmission line and multiconductor transmission line…
(more)
▼ An analytical solution for the
coupled telegrapher’s equations in terms of the
voltage and current on a homogeneous lossy transmission line and multiconductor
transmission line is presented. The resulting telegrapher’s equation solution is obtained
in the form of an exact time
domain propagator operating on the line voltage and current.
It is shown that the analytical equations lead to a stable numerical method that can be
used in the analysis of both homogeneous and inhomogeneous transmission lines. A
numerical dispersion relation is derived proving that this method has no numerical
dispersion down to the two points per wavelength Nyquist limit. Examples are presented
showing that exceptionally accurate results are obtained for lossy single and
multiconductor transmission lines. The method is extended to represent the general
solution to Maxwell’s differential equations in vector matrix form. It is shown that,
given the electromagnetic field and boundary conditions at a given instant in time, the
free space time
domain propagator and corresponding dyadic Green’s functions in 1-, 2-,
and 3-dimensions can be used to calculate the field at all subsequent times.
Advisors/Committee Members: Nevels, Robert D. (advisor), Hemmer, Philip (committee member), Wright, Steven (committee member), Zubairy, Muhammad (committee member).
Subjects/Keywords: Propagator; Time domain analysis; Lossy circuits; Nonuniform transmission line; Coupled transmission lines; Multiconductor transmission lines; Green's function; Maxwell's equations; Path Integral
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Jeong, J. (2009). Analytical time domain electromagnetic field propagators and closed-form solutions for transmission lines. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-1105
Chicago Manual of Style (16th Edition):
Jeong, Jaehoon. “Analytical time domain electromagnetic field propagators and closed-form solutions for transmission lines.” 2009. Doctoral Dissertation, Texas A&M University. Accessed March 07, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-1105.
MLA Handbook (7th Edition):
Jeong, Jaehoon. “Analytical time domain electromagnetic field propagators and closed-form solutions for transmission lines.” 2009. Web. 07 Mar 2021.
Vancouver:
Jeong J. Analytical time domain electromagnetic field propagators and closed-form solutions for transmission lines. [Internet] [Doctoral dissertation]. Texas A&M University; 2009. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1105.
Council of Science Editors:
Jeong J. Analytical time domain electromagnetic field propagators and closed-form solutions for transmission lines. [Doctoral Dissertation]. Texas A&M University; 2009. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1105

Penn State University
12.
Aycock, Kenneth Iven.
Towards Patient-Specific Modeling of Inferior Vena Cava Filter Performance.
Degree: 2016, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/13307kia104
► Inferior vena cava (IVC) filters have been used to mitigate pulmonary embolism (PE) in at-risk patients for nearly half a century. Despite years of innovation,…
(more)
▼ Inferior vena cava (IVC) filters have been used to mitigate pulmonary embolism (PE) in at-risk patients for nearly half a century. Despite years of innovation, IVC filter-related complications remain common, including caval perforation, filter embedment, filter fracture, filter migration, persistence or worsening of deep-vein thrombosis due to IVC thrombosis, and recurrence of PE. In this thesis, a computational workflow is developed and demonstrated for simulating IVC filter placement, hemodynamics, and embolus transport and capture in patient-specific models reconstructed from medical image data.
Patient-specific IVC geometries are first segmented and reconstructed from clinical computed tomography data. Virtual IVC filter placement is then performed using nonlinear finite element analysis with vein-filter contact modeling and nonlinear constitutive models for the vein tissue and nitinol IVC filter. The blood flow and the transport and capture of emboli are simulated using a
coupled computational fluid dynamics / six degree-of-freedom (CFD/6DoF) model that uses an immersed boundary method to resolve the blood flow around the emboli. The embolus-trapping performance of the filter is predicted by systematically varying embolus starting positions, embolus diameters, embolus densities, and IVC orientations in thousands of embolus transport simulations.
Simulations reveal that patient-specific variations in the IVC cross-sectional shape cause a non-uniform distribution of vein–filter contact forces among the filter struts (range of 8-26 mN per strut). Patient-specific anatomical features also generate regions of locally high or low wall shear stress (WSS) and affect secondary flow features such as Dean vortices and flow recirculation regions. Non-Newtonian blood effects are found to be significant in the IVC (e.g., up to a 50% difference in WSS between results obtained using a non-Newtonian model compared with using the Newtonian approximation) due to the predominance of low shear rates. Embolus transport simulations predict that embolus trajectories and capture rates for a given filter are sensitive to the IVC morphology, the embolus-to-blood density ratio, and the direction of the gravitational force (i.e., patient orientation).
With further development and validation, the computational workflow presented herein may be used to guide IVC filter design, to predict the in vivo performance of IVC filters, and to guide the selection and placement of IVC filters on a patient-specific basis. Simulations could also be used to improve preclinical testing standards such that benchtop experiments better mimic the in vivo environment and performance of IVC filters.
Advisors/Committee Members: Keefe B. Manning, Dissertation Advisor/Co-Advisor, Robert L. Campbell, Committee Chair/Co-Chair, Francesco Costanzo, Committee Member, Michael Krane, Committee Member, Donna H. Korzick, Outside Member, Brent A. Craven, Dissertation Advisor/Co-Advisor, Keefe B. Manning, Committee Chair/Co-Chair.
Subjects/Keywords: IVC filter; nitinol; pulmonary embolism; immersed boundary method; six degrees of freedom; inferior vena cava; computational fluid dynamics; finite element analysis; non-Newtonian; hemorheology; hemodynamics; patient-specific; computational modeling; embolus transport; coupled CFD/6-DOF; fictitious domain method
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Aycock, K. I. (2016). Towards Patient-Specific Modeling of Inferior Vena Cava Filter Performance. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/13307kia104
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Aycock, Kenneth Iven. “Towards Patient-Specific Modeling of Inferior Vena Cava Filter Performance.” 2016. Thesis, Penn State University. Accessed March 07, 2021.
https://submit-etda.libraries.psu.edu/catalog/13307kia104.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Aycock, Kenneth Iven. “Towards Patient-Specific Modeling of Inferior Vena Cava Filter Performance.” 2016. Web. 07 Mar 2021.
Vancouver:
Aycock KI. Towards Patient-Specific Modeling of Inferior Vena Cava Filter Performance. [Internet] [Thesis]. Penn State University; 2016. [cited 2021 Mar 07].
Available from: https://submit-etda.libraries.psu.edu/catalog/13307kia104.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Aycock KI. Towards Patient-Specific Modeling of Inferior Vena Cava Filter Performance. [Thesis]. Penn State University; 2016. Available from: https://submit-etda.libraries.psu.edu/catalog/13307kia104
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
13.
Pourheidari, Vahid 1988-.
Cross domain recommender systems using matrix and tensor factorization.
Degree: 2019, University of Saskatchewan
URL: http://hdl.handle.net/10388/11904
► Today, the amount and importance of available data on the internet are growing exponentially. These digital data has become a primary source of information and…
(more)
▼ Today, the amount and importance of available data on the internet are growing exponentially. These digital data has become a primary source of information and the people’s life bonded to them tightly. The data comes in diverse shapes and from various resources and users utilize them in almost all their personal or social activities. However, selecting a desirable option from the huge list of available options can be really frustrating and time-consuming. Recommender systems aim to ease this process by finding the proper items which are more likely to be interested by users. Undoubtedly, there is not even one social media or online service which can continue its’ work properly without using recommender systems. On the other hand, almost all available recommendation techniques suffer from some common issues: the data sparsity, the cold-start, and the new-user problems.
This thesis tackles the mentioned problems using different methods. While, most of the recommender methods rely on using single
domain information, in this thesis, the main focus is on using multi-
domain information to create cross-
domain recommender systems. A cross-
domain recommender system is not only able to handle the cold-start and new-user situations much better, but it also helps to incorporate different features exposed in diverse domains together and capture a better understanding of the users’ preferences which means producing more accurate recommendations.
In this thesis, a pre-clustering stage is proposed to reduce the data sparsity as well. Various cross-
domain knowledge-based recommender systems are suggested to recommend items in two popular social media, the Twitter and LinkedIn, by using different information available in both domains. The state of art techniques in this field, namely matrix factorization and tensor decomposition, are implemented to develop cross-
domain recommender systems. The presented recommender systems based on the
coupled nonnegative matrix factorization and PARAFAC-style tensor decomposition are evaluated using real-world datasets and it is shown that they superior to the baseline matrix factorization collaborative filtering. In addition, network analysis is performed on the extracted data from Twitter and LinkedIn.
Advisors/Committee Members: Deters, Ralph, Vassileva, Julita, Roy, Chanchal, Chen, Li.
Subjects/Keywords: recommender system; cross-domain recommendation; coupled matrix factorization; tensor decomposition; collaborative filtering; hybrid recommender system
…Coupled NMF-based recommender systems to recommend N items; source
domain is the user-skill… …matrix and target domain is the user-account matrix.
Coupled NMF-based recommender systems to… …Cross-domain recommender systems based on the coupled nonnegative matrix
factorization… …cross-domain recommender systems. The coupled matrix factorization-based model
is presented in… …consider user preferences in on domain, the coupled matrix factorization are able to take…
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Pourheidari, V. 1. (2019). Cross domain recommender systems using matrix and tensor factorization. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/11904
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Pourheidari, Vahid 1988-. “Cross domain recommender systems using matrix and tensor factorization.” 2019. Thesis, University of Saskatchewan. Accessed March 07, 2021.
http://hdl.handle.net/10388/11904.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Pourheidari, Vahid 1988-. “Cross domain recommender systems using matrix and tensor factorization.” 2019. Web. 07 Mar 2021.
Vancouver:
Pourheidari V1. Cross domain recommender systems using matrix and tensor factorization. [Internet] [Thesis]. University of Saskatchewan; 2019. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/10388/11904.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Pourheidari V1. Cross domain recommender systems using matrix and tensor factorization. [Thesis]. University of Saskatchewan; 2019. Available from: http://hdl.handle.net/10388/11904
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Indian Institute of Science
14.
Pramanik, Saurav.
Frequency and Time Domain Response Analysis of Transformer Winding for Indirect Measurement of Series Capacitance and Construction of Ladder Network Models.
Degree: PhD, Faculty of Engineering, 2018, Indian Institute of Science
URL: http://etd.iisc.ac.in/handle/2005/3086
► This thesis proposes innovative methods to extract information embedded in the frequency and time domain response of the transformer winding, and utilizes them to suggest…
(more)
▼ This thesis proposes innovative methods to extract information embedded in the frequency and time
domain response of the transformer winding, and utilizes them to suggest solutions to a few tasks that have until now been thought difficult, if not impossible, to resolve. Pursuing this philosophy originated from the basic under- standing that the response of any physical system (behaving largely as a linear time invariant system) has embedded information that characterizes it completely. So, the prerequisite is to evolve ways to extract this information from measured responses. Once that is done, a variety of interesting applications can be envisaged. The two applications considered in this thesis are-
•Investigate indirect measurement of the series capacitance of a transformer winding using the measured frequency or time
domain response
•Explore the possibility of increasing the physical resolution of the ladder network used to model a fully interleaved-disk winding
In the former application, since direct measurement of series capacitance is impossible, alternatives based on indirect measurement were also not attempted. Similarly, in the latter application, the upper limit is known to be fixed by the number of distinctly observable peaks in the magnitude frequency response, so the question of increasing this limit was also never explored. Solutions to these tasks are proposed after a systematic analysis of frequency/time
domain responses of a winding, initially modeled as a lumped parameter ladder network, to extract correlations that exist between them and winding parameters, and finally examine how these relations can be exploited together with the measured responses. Each of the five chapters is dedicated to describe the solution to one task. In each chapter, analytical formulation is presented first, followed by experimental results. Good agreement with the predicted results demonstrates its practicability.
In final summary, indirect measurement of the series capacitance of a winding and en- hancing physical resolution of a ladder network model to represent a fully interleaved- disk winding was successfully demonstrated and they are the main contributions of this thesis.
Advisors/Committee Members: Satish, L (advisor).
Subjects/Keywords: Transformer Winding; Ladder Network Models; Series Capacitance; Interleaved-Disk Winding; Electric Machinery - Windings; Frequency/Time Domain Response; Ladder Network; Winding Transformers; Winding Transformer; Coupled Ladder Network; Constructed Ladder Network; Interleaved Winding; Electrical Engineering
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Pramanik, S. (2018). Frequency and Time Domain Response Analysis of Transformer Winding for Indirect Measurement of Series Capacitance and Construction of Ladder Network Models. (Doctoral Dissertation). Indian Institute of Science. Retrieved from http://etd.iisc.ac.in/handle/2005/3086
Chicago Manual of Style (16th Edition):
Pramanik, Saurav. “Frequency and Time Domain Response Analysis of Transformer Winding for Indirect Measurement of Series Capacitance and Construction of Ladder Network Models.” 2018. Doctoral Dissertation, Indian Institute of Science. Accessed March 07, 2021.
http://etd.iisc.ac.in/handle/2005/3086.
MLA Handbook (7th Edition):
Pramanik, Saurav. “Frequency and Time Domain Response Analysis of Transformer Winding for Indirect Measurement of Series Capacitance and Construction of Ladder Network Models.” 2018. Web. 07 Mar 2021.
Vancouver:
Pramanik S. Frequency and Time Domain Response Analysis of Transformer Winding for Indirect Measurement of Series Capacitance and Construction of Ladder Network Models. [Internet] [Doctoral dissertation]. Indian Institute of Science; 2018. [cited 2021 Mar 07].
Available from: http://etd.iisc.ac.in/handle/2005/3086.
Council of Science Editors:
Pramanik S. Frequency and Time Domain Response Analysis of Transformer Winding for Indirect Measurement of Series Capacitance and Construction of Ladder Network Models. [Doctoral Dissertation]. Indian Institute of Science; 2018. Available from: http://etd.iisc.ac.in/handle/2005/3086
15.
Maikisch, Jonathan Stephen.
Compact silicon diffractive sensor: design, fabrication, and functional demonstration.
Degree: PhD, Electrical and Computer Engineering, 2012, Georgia Tech
URL: http://hdl.handle.net/1853/45882
► The primary objective of the presented research is to develop a class of integrated compact silicon diffractive sensors (CSDS) based on in-plane diffraction gratings. This…
(more)
▼ The primary objective of the presented research is to develop a class of integrated compact silicon diffractive sensors (CSDS) based on in-plane diffraction gratings. This class of sensors uses a silicon-on-insulator (SOI) substrate to limit costs, exploit established fabrication processes, enable integration of supporting electronics, and use the well-understood telecommunications wavelength of 1.55µm. Sensing is achieved by combining constant-diffraction-efficiency and highly-angularly-selective in-plane resonance-
domain diffraction gratings. Detection is based on the diffraction efficiency of the highly angularly selective grating. In this research, the design processes for the constant-diffraction-efficiency and the highly angularly selective gratings are detailed. Grating designs are optimized with rigorous
coupled-wave analysis (RCWA) and simulated with finite-difference time-
domain (FDTD) analysis. Fabrication results are presented for the CSDS gratings. An inductively
coupled plasma (ICP) Bosch etch process enables grating fabrication to within one percent of designed values with nearly vertical sidewalls. Experimental results are presented for individual CSDS gratings, the prototype sensor, and a prototype linear sensor array. The results agree well with simulation. The linear sensor array prototype demonstrates the intrinsic splitting mechanism and forms the basis of a 2-D sensor array. Finally, a toluene sensor was functionally demonstrated. The proof-of-concept device includes a polymer immobilization layer and microfluidic delivery of toluene. Toluene concentrations as low as 100ppm are measured, corresponding to a refractive index change of 3x10⁻⁴ RIU.
Advisors/Committee Members: Gaylord, Thomas (Committee Chair), Bakir, Muhannad (Committee Member), Chatterjee, Abhijit (Committee Member), Davis, Donald (Committee Member), First, Phillip (Committee Member).
Subjects/Keywords: Integrated diffraction grating; Finite-difference time-domain simulation; Rigorous coupled-wave analysis; Diffraction gratings; Microelectronics; Microtechnology
…4
Figure 1.2: A waveguide-coupled SPR sensor fabricated in SOI. The refractive
index of… …the exact formulation with rigorous coupled-wave analysis and the
Kogelnik two-wave coupled… …Polarization-controlled monochromatic light is
coupled to the sample by tapered fiber. Diffracted… …light is coupled outof-plane by out-coupling gratings. It is then imaged by a microscope… …left). The transmitted and reflected light are coupled out-of-plane by
the out-coupling…
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
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APA (6th Edition):
Maikisch, J. S. (2012). Compact silicon diffractive sensor: design, fabrication, and functional demonstration. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/45882
Chicago Manual of Style (16th Edition):
Maikisch, Jonathan Stephen. “Compact silicon diffractive sensor: design, fabrication, and functional demonstration.” 2012. Doctoral Dissertation, Georgia Tech. Accessed March 07, 2021.
http://hdl.handle.net/1853/45882.
MLA Handbook (7th Edition):
Maikisch, Jonathan Stephen. “Compact silicon diffractive sensor: design, fabrication, and functional demonstration.” 2012. Web. 07 Mar 2021.
Vancouver:
Maikisch JS. Compact silicon diffractive sensor: design, fabrication, and functional demonstration. [Internet] [Doctoral dissertation]. Georgia Tech; 2012. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/1853/45882.
Council of Science Editors:
Maikisch JS. Compact silicon diffractive sensor: design, fabrication, and functional demonstration. [Doctoral Dissertation]. Georgia Tech; 2012. Available from: http://hdl.handle.net/1853/45882

University of Cambridge
16.
Chitwood, Patrick.
Mechanisms of multipass membrane protein biogenesis.
Degree: PhD, 2020, University of Cambridge
URL: https://doi.org/10.17863/CAM.56368
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.814544
► A crucial aspect of cellular physiology is the ability of a single cell to remain autonomous and concentrate reagents to improve efficiency. Semi-permeable membranes facilitate…
(more)
▼ A crucial aspect of cellular physiology is the ability of a single cell to remain autonomous and concentrate reagents to improve efficiency. Semi-permeable membranes facilitate autonomy via an outer barrier (plasma membrane) and enclose functional hubs (organelles) to efficiently carry out biological processes. However, cells do not live in isolation and must communicate with neighboring cells, uptake and traffic nutrients, and react to a dynamic extracellular environment. All these processes require integral membrane proteins (IMPs), which are embedded within all cellular membranes. Highlighting their importance is a myriad of human diseases observed upon disruption of their biogenesis. This thesis aims to describe our recent contributions to the understanding of how membrane proteins are made at the endoplasmic reticulum (ER), the primary site of IMP biogenesis in the cell. Although IMPs are defined by a single feature, a transmembrane domain (TMD), the ~5000 encoded in the mammalian genome are diverse. While some contain a single TMD, most feature many biophysically unique TMDs. Productive bio- genesis of most “multipass” membrane proteins requires insertion in a defined topology as well as packing of their TMDs into a helical bundle, often through inter- actions between polar residues unstably located in the hydrophobic lipid bilayer. Neither the mechanisms that facilitate accurate topological insertion or the subsequent stabilization of polar TMDs during IMP biogenesis are completely understood. First, we demonstrate the efficient topogenesis of many GPCRs requires the conserved ER membrane protein complex (EMC). This is supported by biochemical reconstitution of β1-adrenergic receptor (β1AR) insertion in-vitro, which placed EMC at an early step during co-translational insertion of the first TMD (TMD1). In the absence of EMC, TMD1 was topologically inverted or failed to insert altogether. EMC and SRP receptor were sufficient for the correct insertion of TMD1, while insertion of the next TMD required Sec61. Finally, EMC necessity could be by- passed by enforcement of TMD1 topology via an N-terminal signal peptide. Following accurate insertion of TMD1, we define the engagement of a newly identified intramembrane chaperone protein complex that we term the PAT complex. The PAT complex is an obligate heterodimer consisting of the highly conserved proteins CCDC47 and Asterix. A diverse set of multipass membrane proteins show impaired biogenesis upon PAT complex depletion, despite correct topological insertion. Bio- chemical analyses demonstrate PAT complex engages nascent TMDs that contain unshielded polar amino acids but disengages upon substrate folding. Thus, EMC cooperates with Sec61 to co-translationally insert TMDs, ensuring accurate membrane protein topogenesis, while the PAT complex acts after insertion to protect transmembrane domains during their assembly.
Subjects/Keywords: Endoplasmic Reticulum; G-Protein Coupled Receptor; GPCR; Membrane; Multipass membrane proteins; Polytopic membrane protein; Chaperone; Intramembrane chaperone; transmembrane domain; TMD; Membrane insertion; cotranslational; ER membrane protein complex; EMC; PAT complex; CCDC47; Asterix; Biochemistry; Translation; Ribosome
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Chitwood, P. (2020). Mechanisms of multipass membrane protein biogenesis. (Doctoral Dissertation). University of Cambridge. Retrieved from https://doi.org/10.17863/CAM.56368 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.814544
Chicago Manual of Style (16th Edition):
Chitwood, Patrick. “Mechanisms of multipass membrane protein biogenesis.” 2020. Doctoral Dissertation, University of Cambridge. Accessed March 07, 2021.
https://doi.org/10.17863/CAM.56368 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.814544.
MLA Handbook (7th Edition):
Chitwood, Patrick. “Mechanisms of multipass membrane protein biogenesis.” 2020. Web. 07 Mar 2021.
Vancouver:
Chitwood P. Mechanisms of multipass membrane protein biogenesis. [Internet] [Doctoral dissertation]. University of Cambridge; 2020. [cited 2021 Mar 07].
Available from: https://doi.org/10.17863/CAM.56368 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.814544.
Council of Science Editors:
Chitwood P. Mechanisms of multipass membrane protein biogenesis. [Doctoral Dissertation]. University of Cambridge; 2020. Available from: https://doi.org/10.17863/CAM.56368 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.814544

University of Cambridge
17.
Chitwood, Patrick.
Mechanisms of multipass membrane protein biogenesis.
Degree: PhD, 2020, University of Cambridge
URL: https://www.repository.cam.ac.uk/handle/1810/309270
► A crucial aspect of cellular physiology is the ability of a single cell to remain autonomous and concentrate reagents to improve efficiency. Semi-permeable membranes facilitate…
(more)
▼ A crucial aspect of cellular physiology is the ability of a single cell to remain autonomous and concentrate reagents to improve efficiency. Semi-permeable membranes facilitate autonomy via an outer barrier (plasma membrane) and enclose functional hubs (organelles) to efficiently carry out biological processes. However, cells do not live in isolation and must communicate with neighboring cells, uptake and traffic nutrients, and react to a dynamic extracellular environment. All these processes require integral membrane proteins (IMPs), which are embedded within all cellular membranes. Highlighting their importance is a myriad of human diseases observed upon disruption of their biogenesis. This thesis aims to describe our recent contributions to the understanding of how membrane proteins are made at the endoplasmic reticulum (ER), the primary site of IMP biogenesis in the cell. Although IMPs are defined by a single feature, a transmembrane domain (TMD), the ~5000 encoded in the mammalian genome are diverse. While some contain a single TMD, most feature many biophysically unique TMDs. Productive bio- genesis of most “multipass” membrane proteins requires insertion in a defined topology as well as packing of their TMDs into a helical bundle, often through inter- actions between polar residues unstably located in the hydrophobic lipid bilayer. Neither the mechanisms that facilitate accurate topological insertion or the subsequent stabilization of polar TMDs during IMP biogenesis are completely understood. First, we demonstrate the efficient topogenesis of many GPCRs requires the conserved ER membrane protein complex (EMC). This is supported by biochemical reconstitution of β1-adrenergic receptor (β1AR) insertion in-vitro, which placed EMC at an early step during co-translational insertion of the first TMD (TMD1). In the absence of EMC, TMD1 was topologically inverted or failed to insert altogether. EMC and SRP receptor were sufficient for the correct insertion of TMD1, while insertion of the next TMD required Sec61. Finally, EMC necessity could be by- passed by enforcement of TMD1 topology via an N-terminal signal peptide. Following accurate insertion of TMD1, we define the engagement of a newly identified intramembrane chaperone protein complex that we term the PAT complex. The PAT complex is an obligate heterodimer consisting of the highly conserved proteins CCDC47 and Asterix. A diverse set of multipass membrane proteins show impaired biogenesis upon PAT complex depletion, despite correct topological insertion. Bio- chemical analyses demonstrate PAT complex engages nascent TMDs that contain unshielded polar amino acids but disengages upon substrate folding. Thus, EMC cooperates with Sec61 to co-translationally insert TMDs, ensuring accurate membrane protein topogenesis, while the PAT complex acts after insertion to protect transmembrane domains during their assembly.
Subjects/Keywords: Endoplasmic Reticulum; G-Protein Coupled Receptor; GPCR; Membrane; Multipass membrane proteins; Polytopic membrane protein; Chaperone; Intramembrane chaperone; transmembrane domain; TMD; Membrane insertion; cotranslational; ER membrane protein complex; EMC; PAT complex; CCDC47; Asterix; Biochemistry; Translation; Ribosome
Record Details
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Chitwood, P. (2020). Mechanisms of multipass membrane protein biogenesis. (Doctoral Dissertation). University of Cambridge. Retrieved from https://www.repository.cam.ac.uk/handle/1810/309270
Chicago Manual of Style (16th Edition):
Chitwood, Patrick. “Mechanisms of multipass membrane protein biogenesis.” 2020. Doctoral Dissertation, University of Cambridge. Accessed March 07, 2021.
https://www.repository.cam.ac.uk/handle/1810/309270.
MLA Handbook (7th Edition):
Chitwood, Patrick. “Mechanisms of multipass membrane protein biogenesis.” 2020. Web. 07 Mar 2021.
Vancouver:
Chitwood P. Mechanisms of multipass membrane protein biogenesis. [Internet] [Doctoral dissertation]. University of Cambridge; 2020. [cited 2021 Mar 07].
Available from: https://www.repository.cam.ac.uk/handle/1810/309270.
Council of Science Editors:
Chitwood P. Mechanisms of multipass membrane protein biogenesis. [Doctoral Dissertation]. University of Cambridge; 2020. Available from: https://www.repository.cam.ac.uk/handle/1810/309270
18.
Toufayli, Laila.
Stabilisation polynomiale et contrôlabilité exacte des équations des ondes par des contrôles indirects et dynamiques : Polynomial stability and exact controlability of wave equations with indirect and dynamical control.
Degree: Docteur es, Mathématiques, 2013, Université de Strasbourg
URL: http://www.theses.fr/2013STRAD008
► La thèse est portée essentiellement sur la stabilisation et la contrôlabilité de deux équations des ondes moyennant un seul contrôle agissant sur le bord du…
(more)
▼ La thèse est portée essentiellement sur la stabilisation et la contrôlabilité de deux équations des ondes moyennant un seul contrôle agissant sur le bord du domaine. Dans le cas du contrôle dynamique, le contrôle est introduit dans le système par une équation différentielle agissant sur le bord. C'est en effet un système hybride. Le contrôle peut être aussi applique directement sur le bord d'une équation, c'est le cas du contrôle indirecte mais non borne. La nature du système ainsi coupledépend du couplage des équations, et ceci donne divers résultats par la stabilisation (exponentielle et polynomiale) et la contrôlabilité exacte (espace contrôlable). Des nouvelles inégalités d'énergie permettent de mettre en oeuvre la Méthode fréquentielle et la Méthode d'Unicité de Hilbert.
This thesis is concerned with the stabilization and the exact controllability of two wave equations by means of only one control acting on the boundary of the domain. In the case of dynamic control, the control is introduced into the system by differential equation acting on the boundary. It is indeed a hybrid system. The control can be also applied directly on the boundary of one of the equations. In this case, the control is indirect but unbounded. The behavior of the obtained system depends on theways of coupling. Various results are established for the stabilization (exponential or polynomial) and the exact controllability (controllable space of initial data). A new inequality of energy allows to apply the Frequency Method and the Hilbert Uniqueness Method.
Advisors/Committee Members: Rao, Bopeng (thesis director), Wehbe, Ali (thesis director).
Subjects/Keywords: Semi groupes; Équations des ondes; Système d'équations couplées; Contrôle dynamique frontière; Contrôle direct; Méthode de HUM; Méthode des multiplicateurs; Méthode fréquentielle; Stabilité forte; Stabilité uniforme; Stabilité polynomiale; Contrôlabilité exacte; Semi-group; Wave equations; Coupled system; Boundary dynamical control; HUM method; Multiplier method; Frequency domain method; Uniform stability; Polynomial stability; Exact controllability; 515.3; 530.14
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Toufayli, L. (2013). Stabilisation polynomiale et contrôlabilité exacte des équations des ondes par des contrôles indirects et dynamiques : Polynomial stability and exact controlability of wave equations with indirect and dynamical control. (Doctoral Dissertation). Université de Strasbourg. Retrieved from http://www.theses.fr/2013STRAD008
Chicago Manual of Style (16th Edition):
Toufayli, Laila. “Stabilisation polynomiale et contrôlabilité exacte des équations des ondes par des contrôles indirects et dynamiques : Polynomial stability and exact controlability of wave equations with indirect and dynamical control.” 2013. Doctoral Dissertation, Université de Strasbourg. Accessed March 07, 2021.
http://www.theses.fr/2013STRAD008.
MLA Handbook (7th Edition):
Toufayli, Laila. “Stabilisation polynomiale et contrôlabilité exacte des équations des ondes par des contrôles indirects et dynamiques : Polynomial stability and exact controlability of wave equations with indirect and dynamical control.” 2013. Web. 07 Mar 2021.
Vancouver:
Toufayli L. Stabilisation polynomiale et contrôlabilité exacte des équations des ondes par des contrôles indirects et dynamiques : Polynomial stability and exact controlability of wave equations with indirect and dynamical control. [Internet] [Doctoral dissertation]. Université de Strasbourg; 2013. [cited 2021 Mar 07].
Available from: http://www.theses.fr/2013STRAD008.
Council of Science Editors:
Toufayli L. Stabilisation polynomiale et contrôlabilité exacte des équations des ondes par des contrôles indirects et dynamiques : Polynomial stability and exact controlability of wave equations with indirect and dynamical control. [Doctoral Dissertation]. Université de Strasbourg; 2013. Available from: http://www.theses.fr/2013STRAD008

Texas Medical Center
19.
Baameur, Faiza.
IDENTIFICATION OF A CONSERVED CLUSTER IN THE RH DOMAIN OF GRK CRITICAL FOR ACTIVATION BY GPCRs.
Degree: PhD, 2009, Texas Medical Center
URL: https://digitalcommons.library.tmc.edu/utgsbs_dissertations/2
► One of the most critical aspects of G Protein Coupled Receptors (GPCRs) regulation is their rapid and acute desensitization following agonist stimulation. Phosphorylation of…
(more)
▼ One of the most critical aspects of G Protein
Coupled Receptors (GPCRs) regulation is their rapid and acute desensitization following agonist stimulation. Phosphorylation of these receptors by GPCR kinases (GRK) is a major mechanism of desensitization. Considerable evidence from studies of rhodopsin kinase and GRK2 suggests there is an allosteric docking site for the receptor distinct from the GRK catalytic site. While the agonist-activated GPCR appears crucial for GRK activation, the molecular details of this interaction remain unclear. Recent studies suggested an important role for the N- and C-termini and domains in the small lobe of the kinase
domain in allosteric activation; however, neither the mechanism of action of that site nor the RH
domain contributions have been elucidated. To search for the allosteric site, we first indentified evolutionarily conserved sites within the RH and kinase domains presumably deterministic of protein function employing evolutionary trace (ET) methodology and crystal structures of GRK6. Focusing on a conserved cluster centered on helices 3, 9, and 10 in the RH
domain, key residues of GRK5 and 6 were targeted for mutagenesis and functional assays. We found that a number of double mutations within helices 3, 9, and 10 and the N-terminus markedly reduced (50-90%) the constitutive phosphorylation of the β-2 Adrenergic Receptor (β2AR) in intact cells and phosphorylation of light-activated rhodopsin (Rho*) in vitro as compared to wild type (WT) GRK5 or 6. Based on these results, we designed peptide mimetics of GRK5 helix 9 both computationally and through chemical modifications with the goal of both confirming the importance of helix 9 and developing a useful inhibitor to disrupt the GPCR-GRK interaction. Several peptides were found to block Rho* phosphorylation by GRK5 including the native helix 9 sequence, Peptide Builder designed-peptide preserving only the key ET residues, and chemically locked helices. Most peptidomimetics showed inhibition of GRK5 activity greater than 80 % with an IC50 of ~ 30 µM. Alanine scanning of helix 9 has further revealed both essential and non-essential residues for inhibition. Importantly, substitution of Arg 169 by an alanine in the native helix 9-based peptide gave an almost complete inhibition at 30 µM with an IC50 of ~ 10 µM. In summary we report a previously unrecognized crucial role for the RH
domain of GRK5 and 6, and the subsequent identification of a lead peptide inhibitor of protein-protein interaction with potential for specific blockade of GPCR desensitization.
Advisors/Committee Members: Richard B Clark, Carmen W Dessauer, Jeffrey A Frost.
Subjects/Keywords: Beta 2 adrenergic receptor; Rhodopsin; GPCR; G Protein coupled-Receptor Kinase (GRK); Evolutionary Trace; desensitization; RGS homology domain; protein-protein interaction; peptide inhibition; Cell Biology; Pharmacology
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Baameur, F. (2009). IDENTIFICATION OF A CONSERVED CLUSTER IN THE RH DOMAIN OF GRK CRITICAL FOR ACTIVATION BY GPCRs. (Doctoral Dissertation). Texas Medical Center. Retrieved from https://digitalcommons.library.tmc.edu/utgsbs_dissertations/2
Chicago Manual of Style (16th Edition):
Baameur, Faiza. “IDENTIFICATION OF A CONSERVED CLUSTER IN THE RH DOMAIN OF GRK CRITICAL FOR ACTIVATION BY GPCRs.” 2009. Doctoral Dissertation, Texas Medical Center. Accessed March 07, 2021.
https://digitalcommons.library.tmc.edu/utgsbs_dissertations/2.
MLA Handbook (7th Edition):
Baameur, Faiza. “IDENTIFICATION OF A CONSERVED CLUSTER IN THE RH DOMAIN OF GRK CRITICAL FOR ACTIVATION BY GPCRs.” 2009. Web. 07 Mar 2021.
Vancouver:
Baameur F. IDENTIFICATION OF A CONSERVED CLUSTER IN THE RH DOMAIN OF GRK CRITICAL FOR ACTIVATION BY GPCRs. [Internet] [Doctoral dissertation]. Texas Medical Center; 2009. [cited 2021 Mar 07].
Available from: https://digitalcommons.library.tmc.edu/utgsbs_dissertations/2.
Council of Science Editors:
Baameur F. IDENTIFICATION OF A CONSERVED CLUSTER IN THE RH DOMAIN OF GRK CRITICAL FOR ACTIVATION BY GPCRs. [Doctoral Dissertation]. Texas Medical Center; 2009. Available from: https://digitalcommons.library.tmc.edu/utgsbs_dissertations/2

University of Waterloo
20.
Mohebbi, Hamid Reza.
Parametric Interaction in Josephson Junction Circuits and Transmission Lines.
Degree: 2011, University of Waterloo
URL: http://hdl.handle.net/10012/5973
► This research investigates the realization of parametric amplification in superconducting circuits and structures where nonlinearity is provided by Josephson junction (JJ) elements. We aim to…
(more)
▼ This research investigates the realization of parametric amplification in superconducting circuits and structures where nonlinearity is provided by Josephson junction (JJ) elements. We aim to develop a systematic analysis over JJ-based devices toward design of novel traveling-wave Josephson parametric amplifiers (TW-JPA). Chapters of this thesis fall into three categories: lumped JPA, superconducting periodic structures and discrete Josephson transmission lines (DJTL).
The unbiased Josephson junction (JJ) is a nonlinear element suitable for parametric amplification through a four-photon process. Two circuit topologies are introduced to capture the unique property of the JJ in order to efficiently mix signal, pump and idler signals for the purpose of signal amplification. Closed-form expressions are derived for gain characteristics, bandwidth determination, noise properties and impedance for this kind of parametric power amplifier. The concept of negative resistance in the gain formulation is observed. A design process is also introduced to find the regimes of operation for gain achievement. Two regimes of operation, oscillation and amplification, are highlighted and distinguished in the result section. Optimization of the circuits to enhance the bandwidth is also carried out.
Moving toward TW-JPA, the second part is devoted to modelling the linear wave propagation in a periodic superconducting structure. We derive closed-form equations for dispersion and s-parameters of infinite and finite periodic structures, respectively. Band gap formation is highlighted and its potential applications in the design of passive filters and resonators are discussed. The superconducting structures are fabricated using YBCO and measured, illustrating a good correlation with the numerical results.
A novel superconducting Transmission Line (TL), which is periodically loaded by Josephson junctions (JJ) and assisted by open stubs, is proposed as a platform to realize a traveling-wave parametric device. Using the TL model, this structure is modeled by a system of nonlinear partial differential equations (PDE) with a driving source and mixed-boundary conditions at the input and output terminals, respectively. This model successfully emulates parametric and nonlinear microwave propagation when long-wave approximation is applicable. The influence of dispersion to sustain three non-degenerate phased-locked waves through the TL is highlighted.
A rigorous and robust Finite Difference Time Domain (FDTD) solver based on the explicit Lax-Wendroff and implicit Crank-Nicolson schemes has been developed to investigate the device responses under various excitations. Linearization of the wave equation, under small-amplitude assumption, dispersion and impedance analysis is performed to explore more aspects of the device for the purpose of efficient design of a traveling-wave parametric amplifier.
Knowing all microwave characteristics and identifying different regimes of operation, which include impedance properties, cut-off propagation, dispersive…
Subjects/Keywords: Parametric Amplifier; Josephson Junction; Superconducting Device; Traveling-wave Josephson Parametric Amplifier; Discrete Josephson Transmission Line; Finite Difference Time Domain; Spectral Methods; Coupled Wave Equations; Periodic Transmission Line; Superconducting Transmission Line; Dispersion Engineering; Shock Wave; Up/Down Conversion; Three-wave Mixing; Resonant Triads; Phase Matching Condition; Ultra-low Noise Amplifier; Floquet Theorem; Perturbation Thechnique; Multiple Scale Method
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mohebbi, H. R. (2011). Parametric Interaction in Josephson Junction Circuits and Transmission Lines. (Thesis). University of Waterloo. Retrieved from http://hdl.handle.net/10012/5973
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Mohebbi, Hamid Reza. “Parametric Interaction in Josephson Junction Circuits and Transmission Lines.” 2011. Thesis, University of Waterloo. Accessed March 07, 2021.
http://hdl.handle.net/10012/5973.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Mohebbi, Hamid Reza. “Parametric Interaction in Josephson Junction Circuits and Transmission Lines.” 2011. Web. 07 Mar 2021.
Vancouver:
Mohebbi HR. Parametric Interaction in Josephson Junction Circuits and Transmission Lines. [Internet] [Thesis]. University of Waterloo; 2011. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/10012/5973.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Mohebbi HR. Parametric Interaction in Josephson Junction Circuits and Transmission Lines. [Thesis]. University of Waterloo; 2011. Available from: http://hdl.handle.net/10012/5973
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Oxford
21.
Favara, David M.
The biology of ELTD1/ADGRL4 : a novel regulator of tumour angiogenesis.
Degree: PhD, 2017, University of Oxford
URL: http://ora.ox.ac.uk/objects/uuid:0d00af0a-bb43-44bc-ba0b-1f8acbe34bc5
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.748691
► Background: Our laboratory identified ELTD1, an orphan GPCR belonging to the adhesion GPCR family (aGPCR), as a novel regulator of angiogenesis and a potential anti-cancer…
(more)
▼ Background: Our laboratory identified ELTD1, an orphan GPCR belonging to the adhesion GPCR family (aGPCR), as a novel regulator of angiogenesis and a potential anti-cancer therapeutic target. ELTD1 is normally expressed in both endothelial cells and vascular smooth muscle cells and expression is significantly increased in the tumour vasculature. The aim of this project was to analyse ELTD1's function in endothelial cells and its role in breast cancer. Method: 62 sequenced vertebrate genomes were interrogated for ELTD1 conservation and domain alterations. A phylogenetic timetree was assembled to establish time estimates for ELTD1's evolution. After ELTD1 silencing, mRNA array profiling was performed on primary human umbilical vein endothelial cells (HUVECs) and validated with qPCR and confocal microscopy. ELTD1's signalling was investigated by applying the aGPCR âStinger/tethered-agonist Hypothesis'. For this, truncated forms of ELTD1 and peptides analogous to the proposed tethered agonist region were designed. FRET-based 2nd messenger (Cisbio IP-1;cAMP) and luciferase-reporter assays (NFAT; NFÎoB; SRE; SRF-RE; CREB) were performed to establish canonical GPCR activation. To further investigate ELTD1's role in endothelial cells, ELTD1 was stably overexpressed in HUVECS. Functional angiogenesis assays and mRNA array profiling were then performed. To investigate ELTD1 in breast cancer, a panel of cell lines representative of all molecular subtypes were screened using qPCR. Furthermore, an exploratory pilot study was performed on matched primary and regional nodal secondary breast cancers (n=43) which were stained for ELTD1 expression. Staining intensity was then scored and compared with relapse free survival and overall survival. Results: ELTD1 arose 435 million years ago (mya) in bony fish and is present in all subsequent vertebrates. ELTD1 has 3 evolutionary variants of which 2 are most common: one variant with 3 EGFs and a variant with 2 EGFs. Additionally, ELTD1 may be ancestral to members of aGPCR family 2. HUVEC mRNA expression profiling after ELTD1 silencing showed upregulation of the mitochondrial citrate transporter SLC25A1, and ACLY which converts cytoplasmic citrate to Acetyl CoA, feeding fatty acid and cholesterol synthesis, and acetylation. A review of lipid droplet (fatty acid and cholesterol) accumulation by confocal microscopy and flow cytometry (FACS) revealed no changes with ELTD1 silencing. Silencing was also shown to affect the Notch pathway (downregulating the Notch ligand JAG1 and target gene HES2; upregulating the Notch ligand DLL4) and inducing KIT, a mediator of haematopoietic (HSC) and endothelial stem cell (ESC) maintenance. Signalling experiments revealed that unlike other aGPCRs, ELTD1 does not couple to any canonical GPCR pathways (Gαi, Gαs, Gαq, Gα12/13). ELTD1 overexpression in HUVECS revealed that ELTD1 induces an endothelial tip cell phenotype by promoting sprouting and capillary formation, inhibiting lumen anastomoses in…
Subjects/Keywords: 616.99; Cancer biology; Cytology; Molecular biology – Research; Breast – Cancer; Computational evolutionary biology; Neovascularization; Cell signalling; Adhesion GPCR receptors; Endothelial biology; EGF, Latrophilin And Seven Transmembrane Domain Containing 1; Transcriptomics; Angiogenesis; Adhesion GPCR signalling; Adhesion G Protein-Coupled Receptor L4; Adhesion GPCR evolution; ELTD1; Breast cancer; Adhesion GPCR receptor; ADGRL4; Endothelial cells
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APA (6th Edition):
Favara, D. M. (2017). The biology of ELTD1/ADGRL4 : a novel regulator of tumour angiogenesis. (Doctoral Dissertation). University of Oxford. Retrieved from http://ora.ox.ac.uk/objects/uuid:0d00af0a-bb43-44bc-ba0b-1f8acbe34bc5 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.748691
Chicago Manual of Style (16th Edition):
Favara, David M. “The biology of ELTD1/ADGRL4 : a novel regulator of tumour angiogenesis.” 2017. Doctoral Dissertation, University of Oxford. Accessed March 07, 2021.
http://ora.ox.ac.uk/objects/uuid:0d00af0a-bb43-44bc-ba0b-1f8acbe34bc5 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.748691.
MLA Handbook (7th Edition):
Favara, David M. “The biology of ELTD1/ADGRL4 : a novel regulator of tumour angiogenesis.” 2017. Web. 07 Mar 2021.
Vancouver:
Favara DM. The biology of ELTD1/ADGRL4 : a novel regulator of tumour angiogenesis. [Internet] [Doctoral dissertation]. University of Oxford; 2017. [cited 2021 Mar 07].
Available from: http://ora.ox.ac.uk/objects/uuid:0d00af0a-bb43-44bc-ba0b-1f8acbe34bc5 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.748691.
Council of Science Editors:
Favara DM. The biology of ELTD1/ADGRL4 : a novel regulator of tumour angiogenesis. [Doctoral Dissertation]. University of Oxford; 2017. Available from: http://ora.ox.ac.uk/objects/uuid:0d00af0a-bb43-44bc-ba0b-1f8acbe34bc5 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.748691
22.
Dunlap, Ralph S.
Effective reuse of coupling technologies for Earth System Models.
Degree: PhD, Computer Science, 2013, Georgia Tech
URL: http://hdl.handle.net/1853/48943
► Designing and implementing coupled Earth System Models (ESMs) is a challenge for climate scientists and software engineers alike. Coupled models incorporate two or more independent…
(more)
▼ Designing and implementing
coupled Earth System Models (ESMs) is a challenge for climate scientists and software engineers alike.
Coupled models incorporate two or more independent numerical models into a single application, allowing for the simulation of complex feedback effects. As ESMs increase in sophistication, incorporating higher fidelity models of geophysical processes, developers are faced with the issue of managing increasing software complexity.
Recently, reusable coupling software has emerged to aid developers in building
coupled models. Effective reuse of coupling infrastructure means increasing the number of coupling functions reused, minimizing code duplication, reducing the development time required to couple models, and enabling flexible composition of coupling infrastructure with existing constituent model implementations. Despite the widespread availability of software packages that provide coupling infrastructure, effective reuse of coupling technologies remains an elusive goal: coupling models is effort-intensive, often requiring weeks or months of developer time to work through implementation details, even when starting from a set of existing software components. Coupling technologies are never used in isolation: they must be integrated with multiple existing constituent models to provide their primary services, such as model-to-model data communication and transformation. Unfortunately, the high level of interdependence between coupling concerns and scientific concerns has resulted in high interdependence between the infrastructure code and the scientific code within a model’s implementation. These dependencies are a source of complexity which tends to reduce reusability of coupling infrastructure.
This dissertation presents mechanisms for increasing modeler productivity based on improving reuse of coupling infrastructure and raising the level of abstraction at which modelers work. This dissertation argues that effective reuse of coupling technologies can be achieved by decomposing existing coupling technologies into a salient set of implementation-independent features required for coupling high-performance models, increasing abstraction levels at which model developers work, and facilitating integration of coupling infrastructure with constituent models via component-based modularization of coupling features. The contributions of this research include:
(1) a comprehensive feature model that identifies the multi-dimensional design space of coupling technologies used in high-performance Earth System Models,
(2) Cupid, a
domain-specific language and compiler for specifying coupling configurations declaratively and generating their implementations automatically, and
(3) Component-based Coupling Operators (CC-Ops), a modular approach to code reuse of coupling infrastructure based on component technologies for high-performance scientific settings.
The Cupid
domain-specific language is evaluated by specifying a coupling configuration for an example fluid dynamics model and measuring…
Advisors/Committee Members: Rugaber, Spencer (advisor), Mark, Leo (advisor), Bader, David (committee member), Navathe, Shamkant (committee member), Balaji, Venkatramani (committee member).
Subjects/Keywords: Coupled models; Coupling; Earth system model; Software reuse; Component-based software engineering; Domain-specific language; Feature modeling; Earth sciences; Computer simulation; Coupled problems (Complex systems); System analysis; Computer software Reusablility
…for the ESM domain.
Coupled Earth System Models
While we are primarily interested in the… …LIST OF FIGURES
Figure 1: The architecture of a coupled climate model featuring four… …feature analysis, Cupid domain-specific language, and
Component-based coupling operators (… …80
Figure 23: The conceptual architecture of a coupled Earth System Model.
The… …classes in the ESMF domain model .......................................... 88
Figure 26…
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Dunlap, R. S. (2013). Effective reuse of coupling technologies for Earth System Models. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/48943
Chicago Manual of Style (16th Edition):
Dunlap, Ralph S. “Effective reuse of coupling technologies for Earth System Models.” 2013. Doctoral Dissertation, Georgia Tech. Accessed March 07, 2021.
http://hdl.handle.net/1853/48943.
MLA Handbook (7th Edition):
Dunlap, Ralph S. “Effective reuse of coupling technologies for Earth System Models.” 2013. Web. 07 Mar 2021.
Vancouver:
Dunlap RS. Effective reuse of coupling technologies for Earth System Models. [Internet] [Doctoral dissertation]. Georgia Tech; 2013. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/1853/48943.
Council of Science Editors:
Dunlap RS. Effective reuse of coupling technologies for Earth System Models. [Doctoral Dissertation]. Georgia Tech; 2013. Available from: http://hdl.handle.net/1853/48943

Queensland University of Technology
23.
Klenowski, Paul Mark.
Molecular and structural requirements of the ß1L-adrenoceptor.
Degree: 2012, Queensland University of Technology
URL: http://eprints.qut.edu.au/57327/
► Noradrenaline which occurs naturally in the body binds to beta-adrenoceptors on the heart, causing the heart to beat faster and with greater force in response…
(more)
▼ Noradrenaline which occurs naturally in the body binds to beta-adrenoceptors on the heart, causing the heart to beat faster and with greater force in response to increased demand. This enables the heart to provide oxygenated blood to vital organs. Prolonged overstimulation by noradrenaline can be harmful to the heart and lead to the progression of heart disease. In these circumstances beta-adrenoceptors are blocked with drugs called beta-blockers. Beta-blockers block the effects of noradrenaline by binding to the same site on the beta-adrenoceptor. Some beta-blockers such as CGP12177 can also cause increases in heart rate. Therefore it was proposed that CGP12177 could bind in a different place to noradrenaline. The aim of this study was to determine where CGP12177 binds to on the beta-adrenoceptor. The results have revealed a separate binding site named beta-1-low. These results may lead to the development of improved -blockers for the management of heart conditions.
Subjects/Keywords: affinity, agonist, antagonist, ß1l-adrenoceptor, ß1h-adrenoceptor, ß2-adrenoceptor, ß3-adrenoceptor, ß-blocker, (-)-bupranolol, cardiostimulation, cardiovascular, catecholamines, (-)-CGP 12177, (-)-[3h]- CGP 12177, chimera, contractility; crystal structure, cyclic AMP, G-protein coupled receptor, heterologous, human atrial force, human heart failure, (-)-isoprenaline, L-748,337, ligand, low-affinity binding site, L-type Ca2 channel, molecular modelling, non-conventional partial agonists; noradrenaline, pindolol, positive inotropic effect, potency, radioligand binding, recombinant, site-directed mutagenesis, transmembrane domain
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Klenowski, P. M. (2012). Molecular and structural requirements of the ß1L-adrenoceptor. (Thesis). Queensland University of Technology. Retrieved from http://eprints.qut.edu.au/57327/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Klenowski, Paul Mark. “Molecular and structural requirements of the ß1L-adrenoceptor.” 2012. Thesis, Queensland University of Technology. Accessed March 07, 2021.
http://eprints.qut.edu.au/57327/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Klenowski, Paul Mark. “Molecular and structural requirements of the ß1L-adrenoceptor.” 2012. Web. 07 Mar 2021.
Vancouver:
Klenowski PM. Molecular and structural requirements of the ß1L-adrenoceptor. [Internet] [Thesis]. Queensland University of Technology; 2012. [cited 2021 Mar 07].
Available from: http://eprints.qut.edu.au/57327/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Klenowski PM. Molecular and structural requirements of the ß1L-adrenoceptor. [Thesis]. Queensland University of Technology; 2012. Available from: http://eprints.qut.edu.au/57327/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
24.
Ahmed, Aftab.
Metallic nanostructures for enhanced sensing and spectroscopy.
Degree: Dept. of Electrical and Computer Engineering, 2012, University of Victoria
URL: http://hdl.handle.net/1828/4124
► The interaction of light and matter at nanoscale is the subject of study of this dissertation. Particularly, the coupling of light to surface plasmons and…
(more)
▼ The interaction of light and matter at nanoscale is the
subject of study of this dissertation. Particularly, the coupling of light to surface plasmons and their applications in the fields of spectroscopy and sensing is the focus of this work. In terms of spectroscopy, the simple reason of using light to study the chemical structures of different materials is the fact that the energy of light lies in the range of vibrational and electronic transitions of matter. Further, the ability to squeeze light to subwavelength dimensions opens up new possibilities of designing nano-optical devices. In this work we explore surface plasmons for two major applications: (i) Directivity enhanced Raman spectroscopy and (ii) Chemical/biological sensing.
Here a new enhancement phenomenon has been demonstrated experimentally in regards to Raman spectroscopy. Typically, Raman enhancement is considered in terms of local fields only. Here we show the use of directive nanoantennas to provide additional enhancement of two orders of magnitude. The nanoantenna design is optimal in the sense that almost all of the scattered light is
coupled into the numerical aperture of the collecting lens. It is shown that the additional enhancement from directivity pushes the sensitivity to single molecule regime. Further, the out of plane radiation and simplicity of the design makes it an ideal candidate for use with typical commercial microscope setups.
Extra ordinary transmission through nanohole arrays in metallic films is studied for refractive index sensing. Bulk resolution of 6×10-7 is demonstrated by optimizing array dimensions, wavelength of operation, noise reduction and consideration of sensitivity of the detecting CCD camera.
Self-assembled nanostructures are investigated for spectroscopic applications. Time dependent studies of nanorods assembled in end-to-end and side-by-side configurations are conducted. The end-to-end configuration results in higher local field enhancements whereas; the side-by-side configuration shows a reduction in local fields because of the cancellation of radial field components between the neighbouring nanorods. It should be noted that higher fields are desirable for Raman spectroscopy.
Grating structures have been analysed using reduced
coupled mode theory. In most cases, only three lowest order modes prove to be sufficient for accurate description of the system response. Here we present design guidelines for broadband operation and optimization of high quality factor resonators.
Finally the complex reflection coefficient from arbitrary terminated nanorods has been investigated. Phase of reflection plays an important role in the determination of resonance wavelength of nanoantennas. It is shown that the localized surface plasmon resonance of nanoparticles can be considered in terms of propagating surface plasmons along a nanorod of similar geometry where the length of the nanorod approaches zero accompanied with π degrees of phase of reflection.
The contributions made in this work can prove useful in the fields of…
Advisors/Committee Members: Gordon, Reuven (supervisor).
Subjects/Keywords: Nanoantenna; Raman Spectroscopy; Finite Difference Time Domain; Surface Plasmons; Sensing; Coupled Mode Theory; Nanohole Arrays; High Index Contrast Gratings; Self Assembly of Nano Rods
…difference time domain
FIB
Focused ion beam
LSP
Localized surface plasmon
NA
Numerical… …sensor with a resolution of 6×10-7.
This work investigates the method of reduced coupled mode… …analysis of the gratings using rigorous coupled wave analysis
(RCWA).
1.3.2
Antenna… …this work we have employed a commercial FDTD package
from Lumerical Inc.
2.1. Coupled Mode… …contra-directional modes as shown below. The coupled mode
equations governing the mode…
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ahmed, A. (2012). Metallic nanostructures for enhanced sensing and spectroscopy. (Thesis). University of Victoria. Retrieved from http://hdl.handle.net/1828/4124
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Ahmed, Aftab. “Metallic nanostructures for enhanced sensing and spectroscopy.” 2012. Thesis, University of Victoria. Accessed March 07, 2021.
http://hdl.handle.net/1828/4124.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Ahmed, Aftab. “Metallic nanostructures for enhanced sensing and spectroscopy.” 2012. Web. 07 Mar 2021.
Vancouver:
Ahmed A. Metallic nanostructures for enhanced sensing and spectroscopy. [Internet] [Thesis]. University of Victoria; 2012. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/1828/4124.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Ahmed A. Metallic nanostructures for enhanced sensing and spectroscopy. [Thesis]. University of Victoria; 2012. Available from: http://hdl.handle.net/1828/4124
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
25.
Lu, Tianjian.
Multiphysics modeling and simulation for large-scale integrated circuits.
Degree: PhD, Electrical & Computer Engr, 2016, University of Illinois – Urbana-Champaign
URL: http://hdl.handle.net/2142/95323
► This dissertation is a process of seeking solutions to two important and challenging problems related to the design of modern integrated circuits (ICs): the ever…
(more)
▼ This dissertation is a process of seeking solutions to two important and challenging problems related to the design of modern integrated circuits (ICs): the ever increasing couplings among the multiphysics and the large problem size arising from the escalating complexity of the designs. A multiphysics-based computer-aided design methodology is proposed and realized to address multiple aspects of a design simultaneously, which include electromagnetics, heat transfer, fluid dynamics, and structure mechanics. The multiphysics simulation is based on the finite element method for its unmatched capabilities in handling complicate geometries and material properties. The capability of the multiphysics simulation is demonstrated through its applications in a variety of important problems, including the static and dynamic IR-drop analyses of power distribution networks, the thermal-ware high-frequency characterization of through-silicon-via structures, the full-wave electromagnetic analysis of high-power RF/microwave circuits, the modeling and analysis of three-dimensional ICs with integrated microchannel cooling, the characterization of micro- and nanoscale electrical-mechanical systems, and the modeling of decoupling capacitor derating in the power integrity simulations. To perform the large-scale analysis in a highly efficient manner, a
domain decomposition scheme, parallel computing, and an adaptive time-stepping scheme are incorporated into the proposed multiphysics simulation. Significant reduction in computation time is achieved through the two numerical schemes and the parallel computing with multiple processors.
Advisors/Committee Members: Jin, Jian-Ming (advisor), Jin, Jian-Ming (Committee Chair), Schutt-Aine, Jose E. (committee member), Godddard, Lynford L. (committee member), Geubelle, Philippe H. (committee member).
Subjects/Keywords: Multiphysics; Integrated circuits; Electromagnetics; Heat transfer; Conjugate heat transfer; Thermal stress; Electrical-thermal; Microchannel cooling; Coupled electrical-thermal-mechanical; Finite element method; Domain decomposition; Parallel computing
…Domain Decomposition . . . . . . . . . . . . . .
2.2 Parallel Implementation of FETI… …108
108
111
118
129
CHAPTER 8 COUPLED ELECTRICAL-THERMAL-MECHANICAL
SIMULATION FOR THE… …Problem Statement . . . . . . . . . . . . . . . . . . . . . . . . 131
8.2 Coupled Simulation and… …relieve the computation burden of a large-scale analysis, a domain
decomposition scheme… …microwave circuits. Chapter 7 introduces a coupled electricalthermal-fluid simulation in analyzing…
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Lu, T. (2016). Multiphysics modeling and simulation for large-scale integrated circuits. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/95323
Chicago Manual of Style (16th Edition):
Lu, Tianjian. “Multiphysics modeling and simulation for large-scale integrated circuits.” 2016. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed March 07, 2021.
http://hdl.handle.net/2142/95323.
MLA Handbook (7th Edition):
Lu, Tianjian. “Multiphysics modeling and simulation for large-scale integrated circuits.” 2016. Web. 07 Mar 2021.
Vancouver:
Lu T. Multiphysics modeling and simulation for large-scale integrated circuits. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2016. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/2142/95323.
Council of Science Editors:
Lu T. Multiphysics modeling and simulation for large-scale integrated circuits. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2016. Available from: http://hdl.handle.net/2142/95323
.