subject:(Clonal Dynamics)

Mississippi State University

1. Parsons, Jennifer L. Bamboo nutritional composition, biomass production, and palatability to giant pandas: disturbance and temporal effects.

Degree: PhD, Animal and Dairy Sciences, 2013, Mississippi State University

URL: http://sun.library.msstate.edu/ETD-db/theses/available/etd-07032013-213343/ ;

► The giant panda (Ailuropoda melanoleuca) subsists on bamboo, but lacks gastrointestinal modifications for fiber digestion. Pandas display dietary selectivity for certain plant parts; however,… (more)

▼ The giant panda (Ailuropoda melanoleuca) subsists on bamboo, but lacks gastrointestinal modifications for fiber digestion. Pandas display dietary selectivity for certain plant parts; however, cues for selection are unknown, and few have examined panda feeding behavior and bamboo nutrient composition simultaneously. Bamboos are clonal plants, with seasonal cycles of nutrient accumulation related to peak photosynthesis and recruitment. These cycles can be destabilized by aboveground disturbance; however, effects of disturbance on nutritional quality and sustainability of bamboo for primary consumers have not been studied. I examined 4 factors that may contribute to bamboo nutritional quality or sustainable harvest: season, ramet maturity and age, and disturbance. I conducted a 3-year study with Phyllostachys aureosulcata (PLLAU), P. glauca (PLLGL), and P. rubromarginata (PLLRU), at the Shelby County AgriCenter, Memphis TN, applying 3 disturbance treatments in a replicated split-plot design: control, 3% and 20% annual removal of biomass. Bamboo was sampled 8 times/year and divided into shoot, leaf, and culm (central stem) for analysis of crude protein (CP), neutral- and acid-detergent fiber (NDF and ADF), ash, lipid, minerals, and acid-insoluble ash (AIA). I quantified bamboo-stand production, maturity, recruitment and mortality. Biomass removed from PLLAU was used in diet-selection trials with 2 giant pandas, observing consumption of plant parts and bamboo from different disturbance treatments, and sampling bamboo for allelochemical and starch analysis. Disturbance effects were evident only for branch and culm dry mass in PLLRU. In Year 2, drought conditions and peak roosting blackbird populations confounded results. Defoliation and guano deposition preceded changes to soil chemistry, bamboo composition, and stand structure; recruitment increased for PLLRU. After accounting for confounding factors, less-mature bamboo had greater concentrations of most nutrients, but less NDF, ADF, and K. Two-year-old ramets had greater CP, NDF, lipid, P, K, S, and Cu, but less Ca and Fe, than 1-year-old ramets. I confirmed seasonal plant-part selection by pandas, but found no correlation between leaf consumption and AIA concentration. Culm starch analyses were insufficient to establish a clear pattern. I recommend further investigation of non-structural carbohydrates in bamboo, and palatability testing of undisturbed versus disturbed bamboo, which I was unable to examine. Advisors/Committee Members: Brian J. Rude (chair), Francisco Vilella (committee member), Stephen Demarais (committee member), Gary N. Ervin (committee member), Brian S. Baldwin (committee member).

Subjects/Keywords: diet selection; harvest pressure; herbivory; conservation; clonal dynamics; Ailuropoda melanoleuca; Phyllostachys

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APA (6^th Edition):

Parsons, J. L. (2013). Bamboo nutritional composition, biomass production, and palatability to giant pandas: disturbance and temporal effects. (Doctoral Dissertation). Mississippi State University. Retrieved from http://sun.library.msstate.edu/ETD-db/theses/available/etd-07032013-213343/ ;

Chicago Manual of Style (16^th Edition):

Parsons, Jennifer L. “Bamboo nutritional composition, biomass production, and palatability to giant pandas: disturbance and temporal effects.” 2013. Doctoral Dissertation, Mississippi State University. Accessed February 28, 2021. http://sun.library.msstate.edu/ETD-db/theses/available/etd-07032013-213343/ ;.

MLA Handbook (7^th Edition):

Parsons, Jennifer L. “Bamboo nutritional composition, biomass production, and palatability to giant pandas: disturbance and temporal effects.” 2013. Web. 28 Feb 2021.

Vancouver:

Parsons JL. Bamboo nutritional composition, biomass production, and palatability to giant pandas: disturbance and temporal effects. [Internet] [Doctoral dissertation]. Mississippi State University; 2013. [cited 2021 Feb 28]. Available from: http://sun.library.msstate.edu/ETD-db/theses/available/etd-07032013-213343/ ;.

Council of Science Editors:

Parsons JL. Bamboo nutritional composition, biomass production, and palatability to giant pandas: disturbance and temporal effects. [Doctoral Dissertation]. Mississippi State University; 2013. Available from: http://sun.library.msstate.edu/ETD-db/theses/available/etd-07032013-213343/ ;

University of Kentucky

2. Stieha, Christopher. THE EFFECTS OF SPATIAL CONFIGURATION OF POPULATIONS ON THE MAINTENANCE OF THE SEXES IN A CLONAL ORGANISM.

Degree: 2012, University of Kentucky

URL: https://uknowledge.uky.edu/biology_etds/4

► Despite the two-fold advantage to asexual reproduction and its prevalence in a variety of organisms, sexual reproduction is prevalent across all taxa. The maintenance of… (more)

▼ Despite the two-fold advantage to asexual reproduction and its prevalence in a variety of organisms, sexual reproduction is prevalent across all taxa. The maintenance of two sexes is required to ensure genetic diversity and to prevent “evolutionary dead ends,” especially in clonal organisms. Many mechanisms have been proposed for the maintenance of two sexes, ranging from environmental variation and stochasticity, parasites and predators, and mutation rates. Spatial configuration, the size and location of populations with respect to other populations, can allow two competitors to coexist when one would normally be lost. This is especially important when the two competitors are the two sexes. In the clonal organism Marchantia inflexa, I determined that spatial configuration of populations can directly influence the maintenance of both sexes in a population and in an aggregate of populations (a metapopulation) using a combination of theoretical models and field studies. Based on field studies, population size has a significant influence on whether a subpopulation will contain both sexes, with populations smaller than 1m2 being more likely to contain only one sex while populations greater than 1m2 are more likely to contain both sexes. Based on mathematical models, the spatial arrangement of subpopulations within a metapopulation can greatly influence whether a metapopulation maintains both sexes as well as whether the metapopulation persists once one sex has been lost. Field data suggest that distance to nearest neighbor, a measurement of spatial arrangement, influences the maintenance of the sexes within subpopulations, but could affect maintenance differently depending on the metapopulation identity. In some metapopulations, both sexes are maintained when the nearest neighbor is close, while in other streams, one sex is lost when the nearest neighbor is close. When mathematical models are used to explicitly simulate natural metapopulations, the mathematical model predicts the observed sex ratios in one metapopulation, predicts the observed bias in another metapopulation, and fails to predicted observed values in two other metapopulations. Understanding spatial configuration helps us understand the maintenance and loss of sex, but other factors, such as environmental differences, may be required to accurately predict which sex will be lost.

Subjects/Keywords: clonal organisms; maintenance of the sexes; Marchantia inflexa; metapopulation dynamics; spatial configuration; Biology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Stieha, C. (2012). THE EFFECTS OF SPATIAL CONFIGURATION OF POPULATIONS ON THE MAINTENANCE OF THE SEXES IN A CLONAL ORGANISM. (Doctoral Dissertation). University of Kentucky. Retrieved from https://uknowledge.uky.edu/biology_etds/4

Chicago Manual of Style (16^th Edition):

Stieha, Christopher. “THE EFFECTS OF SPATIAL CONFIGURATION OF POPULATIONS ON THE MAINTENANCE OF THE SEXES IN A CLONAL ORGANISM.” 2012. Doctoral Dissertation, University of Kentucky. Accessed February 28, 2021. https://uknowledge.uky.edu/biology_etds/4.

MLA Handbook (7^th Edition):

Stieha, Christopher. “THE EFFECTS OF SPATIAL CONFIGURATION OF POPULATIONS ON THE MAINTENANCE OF THE SEXES IN A CLONAL ORGANISM.” 2012. Web. 28 Feb 2021.

Vancouver:

Stieha C. THE EFFECTS OF SPATIAL CONFIGURATION OF POPULATIONS ON THE MAINTENANCE OF THE SEXES IN A CLONAL ORGANISM. [Internet] [Doctoral dissertation]. University of Kentucky; 2012. [cited 2021 Feb 28]. Available from: https://uknowledge.uky.edu/biology_etds/4.

Council of Science Editors:

Stieha C. THE EFFECTS OF SPATIAL CONFIGURATION OF POPULATIONS ON THE MAINTENANCE OF THE SEXES IN A CLONAL ORGANISM. [Doctoral Dissertation]. University of Kentucky; 2012. Available from: https://uknowledge.uky.edu/biology_etds/4

University of California – Riverside

3. Turcotte, Martin. Experimental Tests of Rapid Eco-Evolutionary Dynamics in a Plant-Herbivore System.

Degree: Evolution, Ecology and Organismal Biology, 2011, University of California – Riverside

URL: http://www.escholarship.org/uc/item/67z2m77x

► Examples of rapid evolution, occurring within a few dozen generations or less, have recently increased substantially. Evolution on these timescales suggests the possibility that rapid… (more)

▼ Examples of rapid evolution, occurring within a few dozen generations or less, have recently increased substantially. Evolution on these timescales suggests the possibility that rapid evolution could reciprocally interact with short-term ecological dynamics, a process termed `Eco-Evolutionary Dynamics'. My dissertation experimentally tests these interactions in an aphid (Myzus persicae) and an undomesticated mustard host (Hirschfeldia incana). Aphid clonal lineages were collected from a local population, and found to differ by up to 17% in intrinsic growth rate. This variation was used to conduct experimental evolution. Experiment 1 quantified how aphid rapid evolution impacts concurrent aphid population dynamics in the greenhouse. I manipulated the amount of genetic variation in intrinsic growth rate by manipulating the genetic composition of aphid populations, which altered rates of evolution. Significant changes in clonal frequencies (or gene frequencies) occurred within a few weeks. Evolving populations grew significantly faster, up to 34%, and reached higher densities compared to non-evolving control populations. I then tested whether rapid evolution significantly impacts population dynamics in the wild. Evolving populations grew significantly faster, up to 42%, and reached up to 67% higher densities compared to non-evolving controls even in the face of environmental variation. Yet evolution only had this impact in the natural uncaged treatments highlighting that ecological context alters the strength of eco-evolutionary dynamics. Finally, the last experiment tested the full eco-evolutionary dynamic cycle of dual causality between ecological dynamics (density) and evolutionary dynamics in the greenhouse. Initial aphid density altered the rate and outcome of evolution. Density also quantitatively and qualitatively altered how rapid evolution impacts population growth rate sometimes accelerating or decelerating growth. This experiment also revealed that rapid evolution and intraspecific density have similar relative impact sizes on population growth rate. My dissertation experimentally quantified strong reciprocal causal interactions between rapid evolution and population dynamics on short-timescales in both greenhouse and in the field in a plant-herbivore system for the first time. Such interactions strongly countermand the assumption that evolution is too slow to influence population dynamics and suggests that ecological and evolutionary predictions would be improved if these interactions were integrated into predictive models.

Subjects/Keywords: Ecology; Evolution and Development; Entomology; Clonal Selection; Community Genetics; Eco-Evolutionary Dynamics; Experimental Evolution; Population Dynamics; Rapid Evolution

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Turcotte, M. (2011). Experimental Tests of Rapid Eco-Evolutionary Dynamics in a Plant-Herbivore System. (Thesis). University of California – Riverside. Retrieved from http://www.escholarship.org/uc/item/67z2m77x

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Turcotte, Martin. “Experimental Tests of Rapid Eco-Evolutionary Dynamics in a Plant-Herbivore System.” 2011. Thesis, University of California – Riverside. Accessed February 28, 2021. http://www.escholarship.org/uc/item/67z2m77x.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Turcotte, Martin. “Experimental Tests of Rapid Eco-Evolutionary Dynamics in a Plant-Herbivore System.” 2011. Web. 28 Feb 2021.

Vancouver:

Turcotte M. Experimental Tests of Rapid Eco-Evolutionary Dynamics in a Plant-Herbivore System. [Internet] [Thesis]. University of California – Riverside; 2011. [cited 2021 Feb 28]. Available from: http://www.escholarship.org/uc/item/67z2m77x.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Turcotte M. Experimental Tests of Rapid Eco-Evolutionary Dynamics in a Plant-Herbivore System. [Thesis]. University of California – Riverside; 2011. Available from: http://www.escholarship.org/uc/item/67z2m77x

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

UCLA

4. Xu, Song. Mathematical Modeling of Clonal Dynamics in Primate Hematopoiesis.

Degree: Biomathematics, 2018, UCLA

URL: http://www.escholarship.org/uc/item/1w37d37p

► Recent developments in cell labeling techniques allow studying activities of the massive cell population at single-cell or clone-level resolution. The generated data are usually featured… (more)

Subjects/Keywords: Systematic biology; Bioinformatics; Immunology; birth-death-immigration process; clonal dynamics; density dependence; granulopoiesis; hematopoietic stem cell; homopolymer error

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Xu, S. (2018). Mathematical Modeling of Clonal Dynamics in Primate Hematopoiesis. (Thesis). UCLA. Retrieved from http://www.escholarship.org/uc/item/1w37d37p

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Xu, Song. “Mathematical Modeling of Clonal Dynamics in Primate Hematopoiesis.” 2018. Thesis, UCLA. Accessed February 28, 2021. http://www.escholarship.org/uc/item/1w37d37p.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Xu, Song. “Mathematical Modeling of Clonal Dynamics in Primate Hematopoiesis.” 2018. Web. 28 Feb 2021.

Vancouver:

Xu S. Mathematical Modeling of Clonal Dynamics in Primate Hematopoiesis. [Internet] [Thesis]. UCLA; 2018. [cited 2021 Feb 28]. Available from: http://www.escholarship.org/uc/item/1w37d37p.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Xu S. Mathematical Modeling of Clonal Dynamics in Primate Hematopoiesis. [Thesis]. UCLA; 2018. Available from: http://www.escholarship.org/uc/item/1w37d37p

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

5. Kester, Lennart Anne. Advances in single-cell sequencing technologies and applications in cancer.

Degree: 2018, University Utrecht

URL: http://dspace.library.uu.nl/handle/1874/363201 ; URN:NBN:NL:UI:10-1874-363201 ; urn:isbn:978-94-6299-883-4 ; URN:NBN:NL:UI:10-1874-363201 ; http://dspace.library.uu.nl/handle/1874/363201

► Broadly speaking, this thesis combines two subjects: advances of single cell sequencing technolgies, and the application of single cell sequencing technologies in a cancer setting.… (more)

▼ Broadly speaking, this thesis combines two subjects: advances of single cell sequencing technolgies, and the application of single cell sequencing technologies in a cancer setting. Since the first single cell sequencing technologies were established, the field has been revolutionized, now allowing the processing of thousands of single cells for either the sequencing of RNA, DNA or even epigenetic marks. In this context chapter 2 and chapter 3 describe advances of the sequencing technologies themselves. Over the last few years single cell sequencing techniques are increasingle used to answer biological questions. Chapters 4, 5 and 6 describe projects in which single cell sequencing was used to answer biological questions. Chapter 1 provides an overview of the development of single cell mRNA sequencing and the algorithms that have been developed to perform lineage tracing based on single cell transcriptomics data. It then describes recent advances in genetic lineage tracing and finishes by describing some very recent techniques that allow the combination of transcriptomic based and genetic lineage tracing from the same single cell. This combination has the potential to give a much deeper understanding of both pathologies and developmental systems. Chapter 2 describes an algorithm that can be used to deconvolve technical variability from single cell mRNA sequencing data. It uses the efficiency of detecting exogenous mRNA species to model technical variation and then uses these models to remove the technical variation from the data. Chapter 3 describes a technique through which it is possible to sequence both the mRNA and the genomic DNA from the same single cell. Chapter 4 uses single cell mRNA sequencing to investigate the tumor heterogeneity of breast tumors. Here, we find that within most breast tumors all major molecular subtypes of breast cancers will be present. Treatment decisions are often based on these molecular classification of tumors into subtypes, therefore this knowledge may hold promise to further optimize cancer treatment. Chapter 5 describes the clonal dynamics of a colon carcinoma model system. Here we show that selectional pressure is much higher in early stage colon cancer organoids than in late stage colon cancer organoids. Furthermore, we show that Copy Number Variation profiles are much more heterogeneous in late stage colon cancer organoids. Chapter 6 describes the molecular events leading up to the development of the first hematopoietic stem cells in the mouse embryo. Chapter 7 contains a discussion of the work presented in this thesis. Advisors/Committee Members: van Oudenaarden, Alexander.

Subjects/Keywords: Single-cell mRNA sequencing; Breast cancer; Colon cancer; Cancer heterogeneity; single-cell DNA sequencing; Clonal dynamics

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Kester, L. A. (2018). Advances in single-cell sequencing technologies and applications in cancer. (Doctoral Dissertation). University Utrecht. Retrieved from http://dspace.library.uu.nl/handle/1874/363201 ; URN:NBN:NL:UI:10-1874-363201 ; urn:isbn:978-94-6299-883-4 ; URN:NBN:NL:UI:10-1874-363201 ; http://dspace.library.uu.nl/handle/1874/363201

Chicago Manual of Style (16^th Edition):

Kester, Lennart Anne. “Advances in single-cell sequencing technologies and applications in cancer.” 2018. Doctoral Dissertation, University Utrecht. Accessed February 28, 2021. http://dspace.library.uu.nl/handle/1874/363201 ; URN:NBN:NL:UI:10-1874-363201 ; urn:isbn:978-94-6299-883-4 ; URN:NBN:NL:UI:10-1874-363201 ; http://dspace.library.uu.nl/handle/1874/363201.

MLA Handbook (7^th Edition):

Kester, Lennart Anne. “Advances in single-cell sequencing technologies and applications in cancer.” 2018. Web. 28 Feb 2021.

Vancouver:

Kester LA. Advances in single-cell sequencing technologies and applications in cancer. [Internet] [Doctoral dissertation]. University Utrecht; 2018. [cited 2021 Feb 28]. Available from: http://dspace.library.uu.nl/handle/1874/363201 ; URN:NBN:NL:UI:10-1874-363201 ; urn:isbn:978-94-6299-883-4 ; URN:NBN:NL:UI:10-1874-363201 ; http://dspace.library.uu.nl/handle/1874/363201.

Council of Science Editors:

Kester LA. Advances in single-cell sequencing technologies and applications in cancer. [Doctoral Dissertation]. University Utrecht; 2018. Available from: http://dspace.library.uu.nl/handle/1874/363201 ; URN:NBN:NL:UI:10-1874-363201 ; urn:isbn:978-94-6299-883-4 ; URN:NBN:NL:UI:10-1874-363201 ; http://dspace.library.uu.nl/handle/1874/363201

6. Kester, Lennart Anne. Advances in single-cell sequencing technologies and applications in cancer.

Degree: 2018, University Utrecht

URL: https://dspace.library.uu.nl/handle/1874/363201 ; URN:NBN:NL:UI:10-1874-363201 ; urn:isbn:978-94-6299-883-4 ; URN:NBN:NL:UI:10-1874-363201 ; https://dspace.library.uu.nl/handle/1874/363201

► Broadly speaking, this thesis combines two subjects: advances of single cell sequencing technolgies, and the application of single cell sequencing technologies in a cancer setting.… (more)

▼ Broadly speaking, this thesis combines two subjects: advances of single cell sequencing technolgies, and the application of single cell sequencing technologies in a cancer setting. Since the first single cell sequencing technologies were established, the field has been revolutionized, now allowing the processing of thousands of single cells for either the sequencing of RNA, DNA or even epigenetic marks. In this context chapter 2 and chapter 3 describe advances of the sequencing technologies themselves. Over the last few years single cell sequencing techniques are increasingle used to answer biological questions. Chapters 4, 5 and 6 describe projects in which single cell sequencing was used to answer biological questions. Chapter 1 provides an overview of the development of single cell mRNA sequencing and the algorithms that have been developed to perform lineage tracing based on single cell transcriptomics data. It then describes recent advances in genetic lineage tracing and finishes by describing some very recent techniques that allow the combination of transcriptomic based and genetic lineage tracing from the same single cell. This combination has the potential to give a much deeper understanding of both pathologies and developmental systems. Chapter 2 describes an algorithm that can be used to deconvolve technical variability from single cell mRNA sequencing data. It uses the efficiency of detecting exogenous mRNA species to model technical variation and then uses these models to remove the technical variation from the data. Chapter 3 describes a technique through which it is possible to sequence both the mRNA and the genomic DNA from the same single cell. Chapter 4 uses single cell mRNA sequencing to investigate the tumor heterogeneity of breast tumors. Here, we find that within most breast tumors all major molecular subtypes of breast cancers will be present. Treatment decisions are often based on these molecular classification of tumors into subtypes, therefore this knowledge may hold promise to further optimize cancer treatment. Chapter 5 describes the clonal dynamics of a colon carcinoma model system. Here we show that selectional pressure is much higher in early stage colon cancer organoids than in late stage colon cancer organoids. Furthermore, we show that Copy Number Variation profiles are much more heterogeneous in late stage colon cancer organoids. Chapter 6 describes the molecular events leading up to the development of the first hematopoietic stem cells in the mouse embryo. Chapter 7 contains a discussion of the work presented in this thesis. Advisors/Committee Members: van Oudenaarden, Alexander.

Subjects/Keywords: Single-cell mRNA sequencing; Breast cancer; Colon cancer; Cancer heterogeneity; single-cell DNA sequencing; Clonal dynamics

Record Details Similar Records Cite « Share

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Kester, L. A. (2018). Advances in single-cell sequencing technologies and applications in cancer. (Doctoral Dissertation). University Utrecht. Retrieved from https://dspace.library.uu.nl/handle/1874/363201 ; URN:NBN:NL:UI:10-1874-363201 ; urn:isbn:978-94-6299-883-4 ; URN:NBN:NL:UI:10-1874-363201 ; https://dspace.library.uu.nl/handle/1874/363201

Chicago Manual of Style (16^th Edition):

Kester, Lennart Anne. “Advances in single-cell sequencing technologies and applications in cancer.” 2018. Doctoral Dissertation, University Utrecht. Accessed February 28, 2021. https://dspace.library.uu.nl/handle/1874/363201 ; URN:NBN:NL:UI:10-1874-363201 ; urn:isbn:978-94-6299-883-4 ; URN:NBN:NL:UI:10-1874-363201 ; https://dspace.library.uu.nl/handle/1874/363201.

MLA Handbook (7^th Edition):

Kester, Lennart Anne. “Advances in single-cell sequencing technologies and applications in cancer.” 2018. Web. 28 Feb 2021.

Vancouver:

Kester LA. Advances in single-cell sequencing technologies and applications in cancer. [Internet] [Doctoral dissertation]. University Utrecht; 2018. [cited 2021 Feb 28]. Available from: https://dspace.library.uu.nl/handle/1874/363201 ; URN:NBN:NL:UI:10-1874-363201 ; urn:isbn:978-94-6299-883-4 ; URN:NBN:NL:UI:10-1874-363201 ; https://dspace.library.uu.nl/handle/1874/363201.

Council of Science Editors:

Kester LA. Advances in single-cell sequencing technologies and applications in cancer. [Doctoral Dissertation]. University Utrecht; 2018. Available from: https://dspace.library.uu.nl/handle/1874/363201 ; URN:NBN:NL:UI:10-1874-363201 ; urn:isbn:978-94-6299-883-4 ; URN:NBN:NL:UI:10-1874-363201 ; https://dspace.library.uu.nl/handle/1874/363201

University of Illinois – Urbana-Champaign

7. Crawford, John Williams. Intraspecific variation in resource use, dormancy investment, and competitive ability in the facultative parthenogen Daphnia pulicaria.

Degree: PhD, Biology, 2017, University of Illinois – Urbana-Champaign

URL: http://hdl.handle.net/2142/97583

► Ecological studies highlight that many species and most populations maintain high degrees of intraspecific (within species or within population) variation in a wide variety of… (more)

▼ Ecological studies highlight that many species and most populations maintain high degrees of intraspecific (within species or within population) variation in a wide variety of life-history traits. This pattern prompts the question: how important is this variation? This is a question that is especially motivating for evolutionary ecologists as we are interested in how intraspecific variation influences evolutionary dynamics. While the maintenance of intraspecific variation is especially common in species that reproduce sexually, it is also common in clonal (and partially clonal) species. In my dissertation, I use the facultatively parthenogenetic zooplankton Daphnia pulicaria to address several questions related to the breadth and consequences of intraspecific variation. Freshwater zooplankton species are important subjects for ecologists. In particular, crustaceans in the genus Daphnia have been studied due to their importance as keystone species in many freshwater lakes. They provide ecosystem services including moving resources from the primary producers up to higher trophic levels and have served as models for grazers in other systems. Decades of research on Daphnia demonstrate substantial interspecific (between species) and intraspecific (within species) variation in how individuals respond to available food resources. These studies targeted both spatial variation in the quality and quantity of algal resources between neighboring lakes and temporal variation (including changes due to decades of eutrophication). This prior research has shown that there is interspecific variation in the ability of species to capitalize on different resource quantities and qualities. One limitation of prior research in this system is that it has concentrated almost exclusively on interspecific variation in resource acquisition and allocation and has largely ignored intraspecific variation within and among populations. Variation in resource quality in natural systems along with trade-offs between and within populations in response to resources makes the Daphnia-algae system ideal for examining intraspecific variation in key life-history traits. Prior work on Daphnia suggests both an interspecific and intraspecific trade-off in response to resource quality between “powerful” and “efficient” species and individuals. In several studies, Alan Tessier and colleagues found that some Daphnia species were better able to capitalize on rich resources and that these “powerful” individuals maximized their growth on both high-quantity and rich-quality resources but were “sensitive” to the decline in resource quality or quantity. Other “efficient” species were better able to maintain their growth on low quantity or poor-quality resources, and were not sensitive to the decline in resource quantity or quality. Further work by Spencer Hall and colleagues extended this examination to intraspecific variation in individual ability to use resources of different qualities. They found similar variation in terms of powerful and efficient strategies… Advisors/Committee Members: Cáceres, Carla E (advisor), Cáceres, Carla E (Committee Chair), Suarez, Andrew V (committee member), Fuller, Rebecca C (committee member), Heath, Katy D (committee member).

Subjects/Keywords: Intraspecific variation; Power-efficiency trade-off; Juvenile growth rate; Clonal selection; Population dynamics; Sexual reproduction; Dormancy; Cyclic parthenogen; Facultative parthenogen; Fitness-associated sex; Competition; Consumer-resource theory; Daphnia; Daphnia pulicaria; Zooplankton

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Crawford, J. W. (2017). Intraspecific variation in resource use, dormancy investment, and competitive ability in the facultative parthenogen Daphnia pulicaria. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/97583

Chicago Manual of Style (16^th Edition):

Crawford, John Williams. “Intraspecific variation in resource use, dormancy investment, and competitive ability in the facultative parthenogen Daphnia pulicaria.” 2017. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed February 28, 2021. http://hdl.handle.net/2142/97583.

MLA Handbook (7^th Edition):

Crawford, John Williams. “Intraspecific variation in resource use, dormancy investment, and competitive ability in the facultative parthenogen Daphnia pulicaria.” 2017. Web. 28 Feb 2021.

Vancouver:

Crawford JW. Intraspecific variation in resource use, dormancy investment, and competitive ability in the facultative parthenogen Daphnia pulicaria. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2017. [cited 2021 Feb 28]. Available from: http://hdl.handle.net/2142/97583.

Council of Science Editors:

Crawford JW. Intraspecific variation in resource use, dormancy investment, and competitive ability in the facultative parthenogen Daphnia pulicaria. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2017. Available from: http://hdl.handle.net/2142/97583

University of South Florida

8. Badgley, Brian D. The Importance of Benthic Habitats as Reservoirs of Persistent Fecal Indicator Bacteria.

Degree: 2009, University of South Florida

URL: https://scholarcommons.usf.edu/etd/3695

► Enterococci are fecal indicator bacteria (FIB) that are used worldwide for water quality assessment. However, evidence of high densities and extended survival of enterococci in… (more)

▼ Enterococci are fecal indicator bacteria (FIB) that are used worldwide for water quality assessment. However, evidence of high densities and extended survival of enterococci in sediments and submerged aquatic vegetation (SAV) has caused uncertainty about their reliability in predicting human health risks from recreational activities in environmental waters. To address the concern that sediments and SAV may harbor large reservoirs of enterococci that can affect water column concentrations, aquatic mesocosms and environmental sampling were employed to investigate patterns of enterococci densities and population structure across the Tampa Bay watershed. In mesocosm experiments and environmental samples, SAV harbored higher densities of enterococci, per mass of substrate, than sediments, and sediments harbored higher densities than water. Population structure assessed by BOX-PCR genotyping was relatively unique in each sample, although slight similarities among samples suggested grouping primarily by location rather than substrate or season. Strain diversity was highly variable, and many samples had low diversity, including nearly monoclonal structure throughout the mesocosm experiments and in several of the environmental samples. Several strains were highly abundant and cosmopolitan (found across sites, seasons, and substrates), and may represent highly naturalized and reproducing indicator bacteria populations that are not directly related to pollution events. When the enterococci densities were viewed from the perspective of the entire aquatic system, SAV-associated enterococci did not comprise a major proportion of the total population, due to the typically large differences in volume of each substrate (SAV vs. sediments vs. water). Instead, the largest proportions of enterococci were typically found in the water or the sediments, depending on the relative volume of substrate or the enterococci density associated with each substrate. Modeling results illustrate that the relative importance of each substrate in terms of FIB populations can shift dramatically over time and space due to changes such as vegetation cover, tidal cycles, and bacteria densities. Furthermore, at several sites within the watershed, estimates of sediment and bacteria resuspension from sediments were very low, suggesting that this process rarely, if ever, significantly affects water column concentrations of enterococci in the watershed.

Subjects/Keywords: Enterococcus; clonal structure; population dynamics; microbial ecology; microbial resuspension; American Studies; Arts and Humanities

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APA (6^th Edition):

Badgley, B. D. (2009). The Importance of Benthic Habitats as Reservoirs of Persistent Fecal Indicator Bacteria. (Thesis). University of South Florida. Retrieved from https://scholarcommons.usf.edu/etd/3695

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Badgley, Brian D. “The Importance of Benthic Habitats as Reservoirs of Persistent Fecal Indicator Bacteria.” 2009. Thesis, University of South Florida. Accessed February 28, 2021. https://scholarcommons.usf.edu/etd/3695.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Badgley, Brian D. “The Importance of Benthic Habitats as Reservoirs of Persistent Fecal Indicator Bacteria.” 2009. Web. 28 Feb 2021.

Vancouver:

Badgley BD. The Importance of Benthic Habitats as Reservoirs of Persistent Fecal Indicator Bacteria. [Internet] [Thesis]. University of South Florida; 2009. [cited 2021 Feb 28]. Available from: https://scholarcommons.usf.edu/etd/3695.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Badgley BD. The Importance of Benthic Habitats as Reservoirs of Persistent Fecal Indicator Bacteria. [Thesis]. University of South Florida; 2009. Available from: https://scholarcommons.usf.edu/etd/3695

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Georgia

9. Straw, William R. 50 years of woody succession at the landscape level.

Degree: 2014, University of Georgia

URL: http://hdl.handle.net/10724/20452

► Woody succession in a 235-hectare oldfield (Field 3-412), in South Carolina, USA, from 1951 through 2001, has been slower and has had different species frequencies… (more)

Subjects/Keywords: Biome; Clonal; Community; Dispersal; Disturbance; Field/Forest Edge; Forest Gap Dynamics; Forest Migration; Hard Mast; Hardwood; Individual; Invasion; Landscape Ecology; Matrix; Oldfield; Patch; Phase; Population; Restoration Ecology; Sere; Soft Mast; So

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Straw, W. R. (2014). 50 years of woody succession at the landscape level. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/20452

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Straw, William R. “50 years of woody succession at the landscape level.” 2014. Thesis, University of Georgia. Accessed February 28, 2021. http://hdl.handle.net/10724/20452.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Straw, William R. “50 years of woody succession at the landscape level.” 2014. Web. 28 Feb 2021.

Vancouver:

Straw WR. 50 years of woody succession at the landscape level. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Feb 28]. Available from: http://hdl.handle.net/10724/20452.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Straw WR. 50 years of woody succession at the landscape level. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/20452

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

10. Youssef, Sarah Hisham Abdelaziz. Somatic Mutation Detection in Leukemia-Derived Circulating DNA: Utility in Monitoring Clonal Dynamics and Disease Response in Pediatric Acute Lymphoblastic Leukemia.

Degree: MS, Pharmaceutical Sciences, 2018, University of Tennessee Health Science Center

URL: https://dc.uthsc.edu/dissertations/458

► Despite the improved outcome associated with current treatment strategies ofpediatric acute lymphoblastic leukemia (ALL), relapse still represents a major challenge. Pediatric ALL demonstrates branched… (more)

Subjects/Keywords: Acute Lymphoblastic Leukemia; Circulating-tumor DNA (Ct-DNA); Clonal Dynamics; Leukemia-derived Circulating DNA; Pediatrics; Somatic Mutations; Medical Genetics; Medical Molecular Biology; Medical Sciences; Medicine and Health Sciences; Pharmacy and Pharmaceutical Sciences

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Youssef, S. H. A. (2018). Somatic Mutation Detection in Leukemia-Derived Circulating DNA: Utility in Monitoring Clonal Dynamics and Disease Response in Pediatric Acute Lymphoblastic Leukemia. (Thesis). University of Tennessee Health Science Center. Retrieved from https://dc.uthsc.edu/dissertations/458

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Youssef, Sarah Hisham Abdelaziz. “Somatic Mutation Detection in Leukemia-Derived Circulating DNA: Utility in Monitoring Clonal Dynamics and Disease Response in Pediatric Acute Lymphoblastic Leukemia.” 2018. Thesis, University of Tennessee Health Science Center. Accessed February 28, 2021. https://dc.uthsc.edu/dissertations/458.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Youssef, Sarah Hisham Abdelaziz. “Somatic Mutation Detection in Leukemia-Derived Circulating DNA: Utility in Monitoring Clonal Dynamics and Disease Response in Pediatric Acute Lymphoblastic Leukemia.” 2018. Web. 28 Feb 2021.

Vancouver:

Youssef SHA. Somatic Mutation Detection in Leukemia-Derived Circulating DNA: Utility in Monitoring Clonal Dynamics and Disease Response in Pediatric Acute Lymphoblastic Leukemia. [Internet] [Thesis]. University of Tennessee Health Science Center; 2018. [cited 2021 Feb 28]. Available from: https://dc.uthsc.edu/dissertations/458.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Youssef SHA. Somatic Mutation Detection in Leukemia-Derived Circulating DNA: Utility in Monitoring Clonal Dynamics and Disease Response in Pediatric Acute Lymphoblastic Leukemia. [Thesis]. University of Tennessee Health Science Center; 2018. Available from: https://dc.uthsc.edu/dissertations/458

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

11. Spinella, Jean-François. Paysage génomique de la leucémie aiguë lymphoblastique de l’enfant.

Degree: 2017, Université de Montréal

URL: http://hdl.handle.net/1866/18534

Subjects/Keywords: leucémie aiguë lymphoblastique de l'enfant; génomique; drivers; mutations rares et récurrentes; mutations somatiques; séquençage de nouvelle génération; algorithme d’apprentissage; rechute; architecture et dynamique clonales; susceptibilité génétique; Childhood acute lymphoblastic leukemia; Genomic; Rare or recurrent driver mutations; Somatic mutations; Next-generation sequencing; Machine learning; Relapse; Clonal architecture and dynamics; Genetic susceptibility; Biology - Molecular / Biologie - Biologie moléculaire (UMI : 0307)

…233 5.5.2. Early and late cALL relapses show different clonal dynamics… …cALL relapses show different clonal dynamics .............................. 252 Figure 3. A… …261 S6 Fig. Early and late cALL relapses show different clonal dynamics (WGS)… …186 4.8.3. Clonal architecture of childhood T-ALL… …225 CHAPITRE 5 - ARTICLE V - Mutational dynamics of early and late relapsed childhood B…

11 more images…

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Spinella, J. (2017). Paysage génomique de la leucémie aiguë lymphoblastique de l’enfant. (Thesis). Université de Montréal. Retrieved from http://hdl.handle.net/1866/18534

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Spinella, Jean-François. “Paysage génomique de la leucémie aiguë lymphoblastique de l’enfant.” 2017. Thesis, Université de Montréal. Accessed February 28, 2021. http://hdl.handle.net/1866/18534.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Spinella, Jean-François. “Paysage génomique de la leucémie aiguë lymphoblastique de l’enfant.” 2017. Web. 28 Feb 2021.

Vancouver:

Spinella J. Paysage génomique de la leucémie aiguë lymphoblastique de l’enfant. [Internet] [Thesis]. Université de Montréal; 2017. [cited 2021 Feb 28]. Available from: http://hdl.handle.net/1866/18534.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Spinella J. Paysage génomique de la leucémie aiguë lymphoblastique de l’enfant. [Thesis]. Université de Montréal; 2017. Available from: http://hdl.handle.net/1866/18534

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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Open Access Theses and Dissertations