subject:(Classical swine fever virus)

University of Sydney

1. Leslie, Edwina Elizabeth Crompton. Pig movements across eastern Indonesia and associated risk of classical swine fever transmission .

Degree: 2012, University of Sydney

URL: http://hdl.handle.net/2123/9316

► Classical swine fever (CSF), a highly contagious Pestivirus, has caused substantial socioeconomic loss for pig farmers in Indonesia since its introduction to this country in… (more)

▼ Classical swine fever (CSF), a highly contagious Pestivirus, has caused substantial socioeconomic loss for pig farmers in Indonesia since its introduction to this country in the mid 1990s. Live pig movements are believed to have facilitated the introduction of CSF into Nusa Tenggara Timur (NTT) province, in eastern Indonesia. This province has the largest pig population, with approximately 85% of households owning at least one pig and the smallholder sector being the dominant industry. Pigs have high cultural and economic importance—being used as an income source, financial security and playing an important role in traditional and religious ceremonies. The number of reported CSF cases in NTT is still increasing, with newly infected islands as recent as 2011. This study was conducted from 2009 to 2012 that investigated live pig movements and the role of markets and villages in CSF transmission across NTT province. The research aimed to identify areas where mitigation measures could be implemented to assist in the control of CSF to reduce its spread in NTT and reduce the potential risk to Australia. Six phases were incorporated into the study to produce findings that could inform decision making. The first phase of the research was to investigate formal pig movements (farm to market) by conducting a market survey where interviews were conducted at nine live pig markets on West Timor, Flores and Sumba islands during September and November 2009, with 292 pig seller and 281 pig buyer respondents. Information was collected by questionnaire on pig movements, pig management, biosecurity, and knowledge on pig health and CSF. Grower and fattener pigs were most commonly sold at market with high annual demand periods identified from August to October. Understanding of CSF and biosecurity was limited, with 85% of sellers and 83% of buyers stating they had no prior knowledge of CSF. Observations were also conducted at each market site which provided baseline information on live pig markets and confirmed an extreme lack of biosecurity with high risk practices having the potential to influence CSF transmission. To investigate the potential role of informal movements of pigs (farm to farm) in CSF transmission, a survey of smallholder pig farmers was conducted from March to May 2010. Eighteen villages were selected across West Timor, Flores and Sumba, and 289 pig farmers were interviewed. Information was collected by questionnaire on pig movements, pig management, biosecurity, and knowledge on pig health and CSF. Most (73.0%) farmersstated they purchased pigs in order to raise the animal on their farm. Over half of the respondents (65.0%) purchased pigs from another farmer and not through a market, and 35.6% reported purchasing at least one pig within the last year. Pigs were sold or left their herd most commonly during the months of January, August, September and October. Information obtained from the market and farmer surveys enabled a social network analysis (SNA) to be conducted on formal and informal movements using information…

Subjects/Keywords: Classical swine fever (CSF); Indonesia

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APA (6^th Edition):

Leslie, E. E. C. (2012). Pig movements across eastern Indonesia and associated risk of classical swine fever transmission . (Thesis). University of Sydney. Retrieved from http://hdl.handle.net/2123/9316

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Leslie, Edwina Elizabeth Crompton. “Pig movements across eastern Indonesia and associated risk of classical swine fever transmission .” 2012. Thesis, University of Sydney. Accessed March 04, 2021. http://hdl.handle.net/2123/9316.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Leslie, Edwina Elizabeth Crompton. “Pig movements across eastern Indonesia and associated risk of classical swine fever transmission .” 2012. Web. 04 Mar 2021.

Vancouver:

Leslie EEC. Pig movements across eastern Indonesia and associated risk of classical swine fever transmission . [Internet] [Thesis]. University of Sydney; 2012. [cited 2021 Mar 04]. Available from: http://hdl.handle.net/2123/9316.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Leslie EEC. Pig movements across eastern Indonesia and associated risk of classical swine fever transmission . [Thesis]. University of Sydney; 2012. Available from: http://hdl.handle.net/2123/9316

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

2. Popescu, Luca Nicolae. Diagnostic techniques for classical swine fever virus.

Degree: PhD, Department of Diagnostic Medicine/Pathobiology, 2017, Kansas State University

URL: http://hdl.handle.net/2097/38269

► Classical swine fever virus (CSFV) is an enveloped, positive strand RNA virus, and member of the genus Pestivirus. It is a highly infectious and transmissible… (more)

Subjects/Keywords: Classical swine fever virus; Foreign animal disease; Diagnostics; Oral fluids; Monoclonal antibodies

10 more images…

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APA (6^th Edition):

Popescu, L. N. (2017). Diagnostic techniques for classical swine fever virus. (Doctoral Dissertation). Kansas State University. Retrieved from http://hdl.handle.net/2097/38269

Chicago Manual of Style (16^th Edition):

Popescu, Luca Nicolae. “Diagnostic techniques for classical swine fever virus.” 2017. Doctoral Dissertation, Kansas State University. Accessed March 04, 2021. http://hdl.handle.net/2097/38269.

MLA Handbook (7^th Edition):

Popescu, Luca Nicolae. “Diagnostic techniques for classical swine fever virus.” 2017. Web. 04 Mar 2021.

Vancouver:

Popescu LN. Diagnostic techniques for classical swine fever virus. [Internet] [Doctoral dissertation]. Kansas State University; 2017. [cited 2021 Mar 04]. Available from: http://hdl.handle.net/2097/38269.

Council of Science Editors:

Popescu LN. Diagnostic techniques for classical swine fever virus. [Doctoral Dissertation]. Kansas State University; 2017. Available from: http://hdl.handle.net/2097/38269

Freie Universität Berlin

3. Anczikowski, Iris. concluding analysis of CSF-eradication and oral imunisation in 2002 - 2007.

Degree: 2010, Freie Universität Berlin

URL: http://dx.doi.org/10.17169/refubium-6816

► A retrospective analysis of the course and the eradication program of Classical Swine Fever (CSF) in wild boar populations in the state of North Rhine-Westphalia,… (more)

▼ A retrospective analysis of the course and the eradication program of Classical Swine Fever (CSF) in wild boar populations in the state of North Rhine-Westphalia, Germany, between 2002 and 2007 was carried out. Its basis were data from questionnaires, which had to be filled out during the process of oral immunisation (o.i.) and from serological and virological findings derived from an international CSF database of hunted wild boars. Learning from years of experience in the eradication of CSF using o.i. in Baden-Wurttemberg and other federal states, North Rhine-Westphalia incorporated o.i. as a further effective method into the CSF eradication program in addition to hunting and hygiene measures to combat epidemics, based on the eradication program of Rhineland Palatinate before the first CSF-virus (CSFV)-infection had been detected. Using a CSF attenuated live vaccine based on the “China- strain” (C-strain) in maize baits (RIEMSER Schweinepestoralvakzine, RIEMSER Arzneimittel AG, Greifswald, Isle of Riems), oral immunisation was performed as a continuous strategy using three double vaccination periods per year (except 2003). The questionnaire data allowed an evaluation of the eradication procedure of o.i. In combination with the data from the CSF-database it provided the basis of causal research into the re-emergence of CSF in 2005. Between 2002 and 2004, hunters had to fill out questionnaires on the distribution and placement of baits in each case. Questionnaire information was related to the nine concerned CSF-affected hunting communities and used for the assessment of other aspects such as respective soil conditions and meteorological data. Data from the CSF-database referring to serological and virological findings of all wild boars examined could also be classified according to the place where individual boars were killed or found dead and to their age. A descriptive analysis of the CSF-database serological data revealed a significant difference in the seroprevalence rates of different age groups. Piglets had low seroprevalences as opposed to sub-adults and adults. In addition, virusprevalence rates showed even greater differences between piglets and sub-adults as well as adults. The fact that virusprevalence is higher among the youngest age class underlines once again the crucial role of piglets in the perpetuation of a CSF-epidemic. Significant differences between hunting communities of the hot-spot-area (hunting communities with the highest number of positive CSF virus detection) and the other hunting communities were assessed by statistical analysis of serological and virological data. The hot- spot-area consists of the hunting communities of Bad Münstereifel and Euskirchen. The use of a conventional live vaccine did not allow distinguishing between antibodies resulting from field infection and vaccination. For that reason, the influence of o.i. could be evaluated only indirectly. In the near future, this differentiation could be brought about by the use of a DIVA-vaccine (differentiation between infected and… Advisors/Committee Members: w (gender), Univ.-Prof. Dr. Karl-Hans Zessin (firstReferee), Dir. u. Prof. Dr. habil. Volker Kaden (furtherReferee), Univ.-Prof. Dr. Karl Heinz Lahrmann (furtherReferee).

Subjects/Keywords: pigs; wild pigs; swine fever; classical swine fever virus; immunization; vaccination; live vaccines; disease control; Germany; 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Anczikowski, I. (2010). concluding analysis of CSF-eradication and oral imunisation in 2002 - 2007. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-6816

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Anczikowski, Iris. “concluding analysis of CSF-eradication and oral imunisation in 2002 - 2007.” 2010. Thesis, Freie Universität Berlin. Accessed March 04, 2021. http://dx.doi.org/10.17169/refubium-6816.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Anczikowski, Iris. “concluding analysis of CSF-eradication and oral imunisation in 2002 - 2007.” 2010. Web. 04 Mar 2021.

Vancouver:

Anczikowski I. concluding analysis of CSF-eradication and oral imunisation in 2002 - 2007. [Internet] [Thesis]. Freie Universität Berlin; 2010. [cited 2021 Mar 04]. Available from: http://dx.doi.org/10.17169/refubium-6816.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Anczikowski I. concluding analysis of CSF-eradication and oral imunisation in 2002 - 2007. [Thesis]. Freie Universität Berlin; 2010. Available from: http://dx.doi.org/10.17169/refubium-6816

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Michigan State University

4. Dunne, Howard W. A study of an encephalitic strain of hog cholera virus.

Degree: PhD, 1951, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:5200

Subjects/Keywords: Classical swine fever

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Dunne, H. W. (1951). A study of an encephalitic strain of hog cholera virus. (Doctoral Dissertation). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:5200

Chicago Manual of Style (16^th Edition):

Dunne, Howard W. “A study of an encephalitic strain of hog cholera virus.” 1951. Doctoral Dissertation, Michigan State University. Accessed March 04, 2021. http://etd.lib.msu.edu/islandora/object/etd:5200.

MLA Handbook (7^th Edition):

Dunne, Howard W. “A study of an encephalitic strain of hog cholera virus.” 1951. Web. 04 Mar 2021.

Vancouver:

Dunne HW. A study of an encephalitic strain of hog cholera virus. [Internet] [Doctoral dissertation]. Michigan State University; 1951. [cited 2021 Mar 04]. Available from: http://etd.lib.msu.edu/islandora/object/etd:5200.

Council of Science Editors:

Dunne HW. A study of an encephalitic strain of hog cholera virus. [Doctoral Dissertation]. Michigan State University; 1951. Available from: http://etd.lib.msu.edu/islandora/object/etd:5200

Michigan State University

5. Weide, Kenneth D. Clinico-pathologic observations of hog cholera in gnotobiotic pigs.

Degree: PhD, 1962, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:13797

Subjects/Keywords: Classical swine fever

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APA (6^th Edition):

Weide, K. D. (1962). Clinico-pathologic observations of hog cholera in gnotobiotic pigs. (Doctoral Dissertation). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:13797

Chicago Manual of Style (16^th Edition):

Weide, Kenneth D. “Clinico-pathologic observations of hog cholera in gnotobiotic pigs.” 1962. Doctoral Dissertation, Michigan State University. Accessed March 04, 2021. http://etd.lib.msu.edu/islandora/object/etd:13797.

MLA Handbook (7^th Edition):

Weide, Kenneth D. “Clinico-pathologic observations of hog cholera in gnotobiotic pigs.” 1962. Web. 04 Mar 2021.

Vancouver:

Weide KD. Clinico-pathologic observations of hog cholera in gnotobiotic pigs. [Internet] [Doctoral dissertation]. Michigan State University; 1962. [cited 2021 Mar 04]. Available from: http://etd.lib.msu.edu/islandora/object/etd:13797.

Council of Science Editors:

Weide KD. Clinico-pathologic observations of hog cholera in gnotobiotic pigs. [Doctoral Dissertation]. Michigan State University; 1962. Available from: http://etd.lib.msu.edu/islandora/object/etd:13797

Michigan State University

6. Howey, Erin Brielle. The pathogenesis of African swine fever : further characterization of infection models and tissue dynamics.

Degree: 2016, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:4463

►

Thesis Ph. D. Michigan State University. Pathobiology 2016

"African swine fever virus (ASFV) causes a reportable and often fatal disease of domestic pigs and wild… (more)

▼

Thesis Ph. D. Michigan State University. Pathobiology 2016

"African swine fever virus (ASFV) causes a reportable and often fatal disease of domestic pigs and wild boars. The current absence of effective prophylaxis or countermeasures makes it a significant agricultural and economic hazard within affected and neighboring regions. Despite extensive ASF research, key elements of the virus-host interaction have yet to be fully explained. Contributing to this knowledge gap is the lack of congruence in infection models amongst investigators. An infection/challenge model that closely simulates natural infection while using precise, measurable inoculation methods, and providing reproducible and quantifiable results is imperative for successful ASFV research and countermeasure development. This dissertation first compares the clinical, viral and shedding dynamics of four modes of infection: Intramuscular (IM), Intranasopharyngeal (INP), Intraoropharyngeal (IOP), and Direct contact (DC), which are commonly used in ASFV investigation. This determines if different inoculation routes/dosages alter the pathogenesis of ASFV in swine and which route most closely resembles natural infection. While developing a standard infection model, a secondary aim of the project was to further clarify the events of infection by detailed characterization of the tissues and cells at different stages of disease. This was investigated in a bipartite approach, both in vivo and in vitro, utilizing virologic and molecular detection methods, as well as immunomicroscopic detection and localization of ASFV antigen alongside cellular markers of interest. Comparison of infection routes revealed that INP simulated natural infection while maintaining reproducibility and ease of control of variables. Examination of an extensive array of postmortem tissue samples revealed low and somewhat route-dictated detection of ASFV at previremic stages of infection, and systemic dissemination of the virus once viremia occurred. Microscopic analysis of tissues indicated that infected cells were distributed within interfollicular regions of lymphoid tissue and the interstitium of non-lymphoid tissue. Immunomicroscpic characterization determined that cells in which ASFV antigen was detected were predominately of monophagocytic origin, with high but variable expression of CD172a, CD163 and lower yet noteworthy expression of CD203a and sialoadhesin. This dissertation presents a comprehensive examination of ASF challenge models, necessary for the prospective standardization of live-animal ASF research. Furthermore, the distinctive characterization of ASFV-infected tissue and cells contribute to the growing understanding of the microenvironment required for the disease. Knowing what tissues and cell types are infected by ASFV can contribute to understanding the molecular or immunologic pathways involved, which viral genes/proteins are necessary for cellular infection. Ultimately this can lead to better targeting of prophylaxis or treatments for ASF." – Pages…

Advisors/Committee Members: Kiupel, Matti, Arzt, Jonathan, Bolin, Steven, Maes, Roger, Mullaney, Thomas.

Subjects/Keywords: African swine fever – Pathogenesis; African swine fever virus; Pathology; Veterinary science

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Howey, E. B. (2016). The pathogenesis of African swine fever : further characterization of infection models and tissue dynamics. (Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:4463

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Howey, Erin Brielle. “The pathogenesis of African swine fever : further characterization of infection models and tissue dynamics.” 2016. Thesis, Michigan State University. Accessed March 04, 2021. http://etd.lib.msu.edu/islandora/object/etd:4463.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Howey, Erin Brielle. “The pathogenesis of African swine fever : further characterization of infection models and tissue dynamics.” 2016. Web. 04 Mar 2021.

Vancouver:

Howey EB. The pathogenesis of African swine fever : further characterization of infection models and tissue dynamics. [Internet] [Thesis]. Michigan State University; 2016. [cited 2021 Mar 04]. Available from: http://etd.lib.msu.edu/islandora/object/etd:4463.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Howey EB. The pathogenesis of African swine fever : further characterization of infection models and tissue dynamics. [Thesis]. Michigan State University; 2016. Available from: http://etd.lib.msu.edu/islandora/object/etd:4463

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Freie Universität Berlin

7. Wirtz, Sabine. Approaches towards novel vaccines that enable the differentiation between infected and vaccinated animals.

Degree: 2014, Freie Universität Berlin

URL: http://dx.doi.org/10.17169/refubium-12922

► Classical swine fever is a highly contagious viral disease of swine and wild boar that leads to important economic losses. In Germany the abatement of… (more)

Subjects/Keywords: Pigs; classical swine fever virus; live vaccines; recombination; markers; 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche

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APA (6^th Edition):

Wirtz, S. (2014). Approaches towards novel vaccines that enable the differentiation between infected and vaccinated animals. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-12922

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Wirtz, Sabine. “Approaches towards novel vaccines that enable the differentiation between infected and vaccinated animals.” 2014. Thesis, Freie Universität Berlin. Accessed March 04, 2021. http://dx.doi.org/10.17169/refubium-12922.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Wirtz, Sabine. “Approaches towards novel vaccines that enable the differentiation between infected and vaccinated animals.” 2014. Web. 04 Mar 2021.

Vancouver:

Wirtz S. Approaches towards novel vaccines that enable the differentiation between infected and vaccinated animals. [Internet] [Thesis]. Freie Universität Berlin; 2014. [cited 2021 Mar 04]. Available from: http://dx.doi.org/10.17169/refubium-12922.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Wirtz S. Approaches towards novel vaccines that enable the differentiation between infected and vaccinated animals. [Thesis]. Freie Universität Berlin; 2014. Available from: http://dx.doi.org/10.17169/refubium-12922

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Kansas State University

8. Olcha, Matthew Evan. Evaluation and comparison of African swine fever virus and vaccinia virus cell entry pathways.

Degree: PhD, Department of Diagnostic Medicine/Pathobiology, 2020, Kansas State University

URL: http://hdl.handle.net/2097/40378

► African swine fever virus (ASFV) causes a highly contagious and deadly disease in swine, with severe economic consequences. In the absence of a vaccine, control… (more)

▼ African swine fever virus (ASFV) causes a highly contagious and deadly disease in swine, with severe economic consequences. In the absence of a vaccine, control measures that target ASFV replication steps are being actively pursued. Due to the high risk of ASFV and its foreign animal disease status, in the United States it is regulated as a select agent and requires BSL-3 containment. In addition, virulent strains of ASFV require primary cells for propagation in tissue culture. In the face of these limitations the ability to use less restrictive surrogate viruses is attractive. One such option is Vaccinia virus (VV), a member of family Poxviridae. Though VV has been used in this capacity before, investigation into its use in Vero cells are limited. When examined using Vero cells treated with various chemical inhibitors, VV produced similar results as the Vero cell adapted strain of ASFV, suggesting the two viruses behave similar during cell entry and early infection. VV provides a suitable surrogate virus for ASFV research, as well as a virus that can replicate in both Vero cells and primary swine macrophages, though there are limited studies regarding the latter. Swine macrophages and monocytes are the primary target cells for ASFV infection, though factors responsible for this tropism are unknown. A significant body of work identified CD163 as required for ASFV cell entry; however, macrophages lacking CD163 and CD163 knockout pigs support infection. ASFV also utilizes macropinocytosis, a non-specific cellular uptake pathway, to enter the cell. This may explain why CD163KO pigs can be infected with ASFV. The present data indicates that CD163 is not required for ASFV infection, but does not rule out its involvement entirely. Macropinocytosis inhibitors used in all experiments included EIPA, cytochalasin D, and wortmannin. Inhibitors of clathrin-mediated endocytosis included chlorpromazine and dynasore. ML-7 inhibits myosin light chain kinase and nocodazole inhibits microtubule dynamics. All seven inhibitors reduced the infection rate, consistent with ASFV using both macropinocytosis and clathrin- and dynamin-dependent endocytosis, as well as non-muscle myosin II and microtubules during stages of entry and early infection. However, the inhibitor effects were not significantly different between wildtype and CD163KO macrophages, suggesting that CD163 lacks involvement with ASFV infection. This work provides a framework for VV as an early infection surrogate model in Vero cells, and helps close the door on the CD163 controversy. Advisors/Committee Members: Raymond R. R. Rowland.

Subjects/Keywords: African swine fever; CD163; vaccinia virus; virus cell entry

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Olcha, M. E. (2020). Evaluation and comparison of African swine fever virus and vaccinia virus cell entry pathways. (Doctoral Dissertation). Kansas State University. Retrieved from http://hdl.handle.net/2097/40378

Chicago Manual of Style (16^th Edition):

Olcha, Matthew Evan. “Evaluation and comparison of African swine fever virus and vaccinia virus cell entry pathways.” 2020. Doctoral Dissertation, Kansas State University. Accessed March 04, 2021. http://hdl.handle.net/2097/40378.

MLA Handbook (7^th Edition):

Olcha, Matthew Evan. “Evaluation and comparison of African swine fever virus and vaccinia virus cell entry pathways.” 2020. Web. 04 Mar 2021.

Vancouver:

Olcha ME. Evaluation and comparison of African swine fever virus and vaccinia virus cell entry pathways. [Internet] [Doctoral dissertation]. Kansas State University; 2020. [cited 2021 Mar 04]. Available from: http://hdl.handle.net/2097/40378.

Council of Science Editors:

Olcha ME. Evaluation and comparison of African swine fever virus and vaccinia virus cell entry pathways. [Doctoral Dissertation]. Kansas State University; 2020. Available from: http://hdl.handle.net/2097/40378

Freie Universität Berlin

9. Schulz, Katja. Classical Swine Fever in wild boar: Evaluation of different surveillance strategies in times of disease freedom.

Degree: 2016, Freie Universität Berlin

URL: http://dx.doi.org/10.17169/refubium-4752

► In the present study, a comprehensive evaluation of the currently implemented surveillance system for Classical Swine fever (CSF) in German wild boar was conducted and… (more)

▼ In the present study, a comprehensive evaluation of the currently implemented surveillance system for Classical Swine fever (CSF) in German wild boar was conducted and compared to alternative, risk-based surveillance strategies. Risk-factors for infection of wild boar with the CSF-virus and for detection of wild boar infected with CSF were identified and used to inform and develop alternative surveillance strategies. The currently applied surveillance strategy was defined as the reference strategy. The study area targeted the federal states of Rhineland-Palatinate (RP) and Mecklenburg-Western Pomerania (MV). To assess the performance of the surveillance strategies, sensitivity and timeliness of the strategies were examined utilizing a simulation model, parameterized with real data from RP and MV. These included estimates of population size, data regarding population structure, hunting data and the serological course of CSF-infection in wild boar. The sensitivity was determined by measuring the probability of detection of a CSF-infection within one year. Timeliness was defined as the time between introduction and detection of a CSF-infection. The acceptability of the surveillance strategies was examined using methods of participatory epidemiology. Due to the key role of hunters within the surveillance system for CSF in wild boar, the acceptability of the currently used and the alternative surveillance strategies by hunters was analyzed and compared. The cost-effectiveness of the surveillance strategies was investigated with the help of the simulation model. Age, population density, seasonality and the examination of samples, resulting from passive surveillance were identified as risk-factors. On the basis of these factors, 31 additional surveillance strategies were developed and evaluated against the reference strategy. As it was not possible to investigate all evaluation attributes for each surveillance strategy, the analyses were conducted in different blocks, in which the strategies for the same evaluation attributes were investigated and compared to each other. In three of the four blocks, an age-dependent surveillance strategy showed the best overall result. The strategy, in which sampling took place only within the age class of sub-adults, resulted in the highest level of acceptability by the hunters. In this strategy timeliness was slightly higher than in the currently implemented strategy. However, both cost and detection probability were almost the same. It was shown that risk-based surveillance strategies can provide effective alternatives to conventional surveillance. Advisors/Committee Members: w (gender), Prof. Dr. Franz J. Conraths (firstReferee), Univ.-Prof. Dr. Marcus Doherr (furtherReferee), Prof. Dr. Volker Moennig (furtherReferee).

Subjects/Keywords: classical swine fever virus; epidemiology; monitoring; economic evaluation; risk analysis; risk factors; wild boar; timeliness; 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche

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APA (6^th Edition):

Schulz, K. (2016). Classical Swine Fever in wild boar: Evaluation of different surveillance strategies in times of disease freedom. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-4752

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Schulz, Katja. “Classical Swine Fever in wild boar: Evaluation of different surveillance strategies in times of disease freedom.” 2016. Thesis, Freie Universität Berlin. Accessed March 04, 2021. http://dx.doi.org/10.17169/refubium-4752.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Schulz, Katja. “Classical Swine Fever in wild boar: Evaluation of different surveillance strategies in times of disease freedom.” 2016. Web. 04 Mar 2021.

Vancouver:

Schulz K. Classical Swine Fever in wild boar: Evaluation of different surveillance strategies in times of disease freedom. [Internet] [Thesis]. Freie Universität Berlin; 2016. [cited 2021 Mar 04]. Available from: http://dx.doi.org/10.17169/refubium-4752.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Schulz K. Classical Swine Fever in wild boar: Evaluation of different surveillance strategies in times of disease freedom. [Thesis]. Freie Universität Berlin; 2016. Available from: http://dx.doi.org/10.17169/refubium-4752

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Pretoria

10. Gers, Sophette. A histological and immunohistochemical study of the lesions observed in desert warthogs (Phacochoerus africanus) and bushpigs (Potamochoerus porcus) following experimental challenge with CSF virus.

Degree: Paraclinical Sciences, 2011, University of Pretoria

URL: http://hdl.handle.net/2263/31364

► Afrikaans: Wilde Afrika varke, nl. vlakvarke (Phacocoerus africanus) en bosvarke (Potamochoerus larvatus) was eksperimenteel infekteer met europese varkpes virus nadat die siekte in kommersiële mak… (more)

▼ Afrikaans: Wilde Afrika varke, nl. vlakvarke (Phacocoerus africanus) en bosvarke (Potamochoerus larvatus) was eksperimenteel infekteer met europese varkpes virus nadat die siekte in kommersiële mak varke diagnoseer is in 2005 (dit was tipeer as subtipe 2.1). Geen inligiting oor die vatbaarheid of potensiële letsels weens europese varkpes infeksie in hierdie wilde varke was beskikbaar nie. Sewe wilde onvolwasse vlakvarke en ses bosvarke is gevang, na die isolasie eenheid van die Onderstepoort Veterinêre Instituut se oor-grens siekte afdeling geneem en intranasal geïnfekteer met die Suid-Afrikaanse isolaat van 2005. Twee in-kontak kontrole diere van dieselfde spesie is gebruik in elke eksperiment om intra-spesie oordraging vas te stel en twee mak varke om virus lewensvatbaarheid en virulensie te demonstreer. Oorlewende diere is uitgesit na 44 dae. Formalien gefikseerde weefsel monsters is versamel van hulle, sowel as van diere wat uitgesit is tydens die eksperiment. Die vlakvarke was klinies normal regdeur die eksperiment, maar het wel histologiese letsels ontwikkel wat subtiel was en ook nie altyd teenwoordig in alle gevalle nie. Drie vlakvarke, waarvan een ‘n in-kontak dier was, het prominente limfo-plasmasitiese perivaskulêre flensing in hul breine ontwikkel. Subtiele letsels het klein hoeveelhede limfoplasmasitiese infiltrasies in verskeie organe en somtyds perivaskulêre flensing ingesluit. In teenstelling, het die bosvarke uitgesproke kliniese tekens soortgelyk aan Europese varkpes in mak varke, ontwikkel. Vier uit die ses diere, insluitend twee in-kontak diere is dood of uitgesit tydens die eksperiment. Met nadoodse ondersoek is daar intestinale nekrose en ulserasie, purulente rinitis en pneumonie gevind. Diere wat dood is, het limfoïede nekrose en limfoïede uitputting getoon, terwyl die oorlewende bosvarke perivaskulêre flensing met limfo-plasma selle in verskeie organe ontwikkel het. Immunohistochemiese demonstrasie van Europese varkpes virus antigen deur gebruik van ‘n kommersieël beskikbare muis monoklonale teenligaam, WH303, het duidelike wydverspreide kleuring in meeste weefsel van die die vlakvarke, bosvarke en mak varke getoon. ‘n Wye reeks van weefsel en sel tipes het met die teenliggam reageer naamlik: mononukliêre selle (monosietmakrofage en limfo-plasma selle), follikulêre retikulêre selle, epiteel, vaskulêre endoteel, mesoteel, gladde spier selle en fibroblaste. Weefsel wat gemerk is met die teenliggaam het ingesluit: mangels, limfknope, milt, derde ooglid, adrenaal klier, urienblaas, vel, lewer, nier, long, sekere selle in die sentrale senuwee stelsel, soos die koroïed pleksus, verskeie dele van die gastro-intestinale stelsel sowel as klier weefsel soos die pankreas en speekselklier. Die mangels was die mees konsekwent gemerkte weefsel, terwyl geen kleuring gevind is in miosiete van skelet of hartspier nie. Uit hierdie werk kon daar afgelei word dat vlakvarke en bosvarke vatbaar is vir Europese varkpes en dat intra-spesie oordraging plaasvind onder eksperimentele… Advisors/Committee Members: Williams, Mark C. (advisor).

Subjects/Keywords: UCTD; Classical swine fever; Immunoperoxidase; Immunohistochemistry; Intra-species transmission

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Gers, S. (2011). A histological and immunohistochemical study of the lesions observed in desert warthogs (Phacochoerus africanus) and bushpigs (Potamochoerus porcus) following experimental challenge with CSF virus. (Masters Thesis). University of Pretoria. Retrieved from http://hdl.handle.net/2263/31364

Chicago Manual of Style (16^th Edition):

Gers, Sophette. “A histological and immunohistochemical study of the lesions observed in desert warthogs (Phacochoerus africanus) and bushpigs (Potamochoerus porcus) following experimental challenge with CSF virus.” 2011. Masters Thesis, University of Pretoria. Accessed March 04, 2021. http://hdl.handle.net/2263/31364.

MLA Handbook (7^th Edition):

Gers, Sophette. “A histological and immunohistochemical study of the lesions observed in desert warthogs (Phacochoerus africanus) and bushpigs (Potamochoerus porcus) following experimental challenge with CSF virus.” 2011. Web. 04 Mar 2021.

Vancouver:

Gers S. A histological and immunohistochemical study of the lesions observed in desert warthogs (Phacochoerus africanus) and bushpigs (Potamochoerus porcus) following experimental challenge with CSF virus. [Internet] [Masters thesis]. University of Pretoria; 2011. [cited 2021 Mar 04]. Available from: http://hdl.handle.net/2263/31364.

Council of Science Editors:

Gers S. A histological and immunohistochemical study of the lesions observed in desert warthogs (Phacochoerus africanus) and bushpigs (Potamochoerus porcus) following experimental challenge with CSF virus. [Masters Thesis]. University of Pretoria; 2011. Available from: http://hdl.handle.net/2263/31364

Univerzitet u Beogradu

11. Stanojević, Slavoljub G. Евалуација епизоотиолошких метода у поступку одређивања обухвата имунизацијом против класичне куге свиња у Републици Србији.

Degree: Fakultet veterinarske medicine, 2017, Univerzitet u Beogradu

URL: https://fedorabg.bg.ac.rs/fedora/get/o:14482/bdef:Content/get

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Биотехничке науке - Ветеринарство, Епизоотиологија / Agricultural Science - Veterinary, Epizootiology

Класична куга свиња (ККС) је веома контагиозно обољење домаћих и дивљих свиња. Економски посматрано… (more)

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Биотехничке науке - Ветеринарство, Епизоотиологија / Agricultural Science - Veterinary, Epizootiology

Класична куга свиња (ККС) је веома контагиозно обољење домаћих и дивљих свиња. Економски посматрано ККС представља највећу претњу свињарској производњи једне земље. У многим земљама, ККС је успешно искорењена применом опсежних мера контроле присуства вируса ККС у природним резервоарима, биосигурносне заштите, нешкодљивог уништавања оболелих свиња, контроле промета животиња, упоредо са програмом масовне вакцинације. Успешно заустављање циркулације вируса ККС кроз пријемчиву популацију и прекидање ланца инфекције уз примену вакцинације, захтева висок ниво имунизације свиња. Ако се вакцинација спроводи систематски на територији целе земље, долази до значајног смањивања клиничких случајева ККС и до заустављања циркулације вируса. Искуства су показала да је ерадикацију уз примену масовне вакцинације могуће постићи у року од годину дана. Да би се обезбедио одговарајући ниво имунитета стада и избегли нежељени ефекти ниског обухвата вакцинацијом, као што је присуство „маскираних“ случајева ККС, потребно је обезбедити константну вакцинацију свиња на терену. Упоредо са имунопрофиласком неопходно је спроводити и мониторинг вакцинације. Мониторинг вакцинације је заснован на плану узорковања, теренском истраживању и препознавању ризичних фактора који условљавају низак обухват имунизацијом. Циљ испитивања је био да се одреди одговарајући поступак израчунавања величине репрезентативног узорка, односно потребног броја насељених места, породичних фарми, сеоских газдинстава и свиња, код којих треба спровести епизоотиолошко истраживање и испитивање сероконверзије, ради одређивања обухвата вакцинацијом против ККС. У раду је описана студија пресека, примерена екстензивним условима држања свиња и урађен прорачун репрезентативног узорка на нивоу популације свиња у Републици Србији. Такође је извршено истраживање обухвата вакцинацијом против ККС на територији три општине у Републици Србији и испитана ефикасност имунизације.

Advisors/Committee Members: Valčić, Miroslav, 1955-.

Subjects/Keywords: vaccination coverage; classical swine fever; monitoring; sample size

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Stanojević, S. G. (2017). Евалуација епизоотиолошких метода у поступку одређивања обухвата имунизацијом против класичне куге свиња у Републици Србији. (Thesis). Univerzitet u Beogradu. Retrieved from https://fedorabg.bg.ac.rs/fedora/get/o:14482/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Stanojević, Slavoljub G. “Евалуација епизоотиолошких метода у поступку одређивања обухвата имунизацијом против класичне куге свиња у Републици Србији.” 2017. Thesis, Univerzitet u Beogradu. Accessed March 04, 2021. https://fedorabg.bg.ac.rs/fedora/get/o:14482/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Stanojević, Slavoljub G. “Евалуација епизоотиолошких метода у поступку одређивања обухвата имунизацијом против класичне куге свиња у Републици Србији.” 2017. Web. 04 Mar 2021.

Vancouver:

Stanojević SG. Евалуација епизоотиолошких метода у поступку одређивања обухвата имунизацијом против класичне куге свиња у Републици Србији. [Internet] [Thesis]. Univerzitet u Beogradu; 2017. [cited 2021 Mar 04]. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:14482/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Stanojević SG. Евалуација епизоотиолошких метода у поступку одређивања обухвата имунизацијом против класичне куге свиња у Републици Србији. [Thesis]. Univerzitet u Beogradu; 2017. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:14482/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Univerzitet u Beogradu

12. Plavšić, Budimir R., 1970-. Epizootiološki i ekonomski efekti sprovođenja kontinuirane vakcinacije svinja protiv klasične kuge u Republici Srbiji.

Degree: Fakultet veterinarske medicine, 2017, Univerzitet u Beogradu

URL: https://fedorabg.bg.ac.rs/fedora/get/o:14495/bdef:Content/get

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Preventivna veterinarska medicina - Mikrobiologija sa imunologijom / Preventive veterinary medicine - Microbiology with immunology

virusnog porekla, čije pojavljivanje ima izuzetno veliki zdravstveni, socijalni i… (more)

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Preventivna veterinarska medicina - Mikrobiologija sa imunologijom / Preventive veterinary medicine - Microbiology with immunology

virusnog porekla, čije pojavljivanje ima izuzetno veliki zdravstveni, socijalni i ekonomski uticaj. U mnogim delovima sveta, veliki napori i sredstva se ulažu u sprečavanje pojavljivanje bolesti i smanjenja ekonomskih troškova izazvanih KKS a sve u cilju njenog potpunog iskorenjivanja. Bolest se pojavljuje u većem broju zemalja Azije, centralne i južne Amerike, delovima Afrike i Evrope. Uspeh u iskorenjivanju postignut je u većem broju država, uključujući Severnu Ameriku, Australaziju i Severnu Evropu, gde se status zemalja slobodnih od KKS održava bez primene vakcinacije. U Zapadnoj Evropi, ostvarena je progresivna eradikacija u toku poslednje dve dekade 20. veka uz zabranu vakcinacije u zemljama članicama EU od 1990. godine. Međutim, periodično je dolazilo do unošenja virusa KKS u populaciju domaćih svinja preko divljih svinja ili uvozom domaćih svinja iz inostranstva. Pojava KKS u zemljama koje ne primenjuju preventivnu vakcinaciju ili su slobodne od bolesti može dovesti do velikih epizootija jer je celokupna populacija domaćih svinja veoma prijemčiva na virus. Zbog toga je kontinuirano vršenje aktivnog i pasivnog nadzora nad KKS od fundamentalnog značaja za sprečavanje pojave i širenja ove zaraze jer doprinosi da se eventualno izbijanje bolesti otkrije na vreme kao i da se brzo uspostave kontrolne mere u cilju sprečavanja daljeg širenja virusa KKS. Za efikasno sprovođenje potpunog iskorenjivanja KKS, pored definisanja principa kontrole KKS, kratkoročnih, srednjoročnih i dugoročnih prioritetnih aktivnosti, obezbeđivanja odgovarajućeg pravnog okvira, dijaloga i podele odgovornosti između najvažnijih institucija, službi i poslovnih subjekata, potrebno je osigurati odgovarajuće finansijske, kadrovske i druge resurse, kao i kontinuiranu edukaciju i jačanje kapaciteta nadležnih službi. U ispitivanjima su opisani epizootiološki i ekonomski aspekti Programa kontrole KKS uz primenu vakcinacije koji se sprovodio od 2006. do 2012. godine, pravni okvir i strateške mere koju državna veterinarska administracija i operativne veterinarske službe sprovode u cilju kontrole i potpunog iskorenjivanja KKS u Srbiji, kao i efekti primene tih mera...

Advisors/Committee Members: Ašanin, Ružica, 1947-.

Subjects/Keywords: classical swine fever; animal health economics; vaccination; epidemiological surveillance; eradication

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Plavšić, Budimir R., 1. (2017). Epizootiološki i ekonomski efekti sprovođenja kontinuirane vakcinacije svinja protiv klasične kuge u Republici Srbiji. (Thesis). Univerzitet u Beogradu. Retrieved from https://fedorabg.bg.ac.rs/fedora/get/o:14495/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Plavšić, Budimir R., 1970-. “Epizootiološki i ekonomski efekti sprovođenja kontinuirane vakcinacije svinja protiv klasične kuge u Republici Srbiji.” 2017. Thesis, Univerzitet u Beogradu. Accessed March 04, 2021. https://fedorabg.bg.ac.rs/fedora/get/o:14495/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Plavšić, Budimir R., 1970-. “Epizootiološki i ekonomski efekti sprovođenja kontinuirane vakcinacije svinja protiv klasične kuge u Republici Srbiji.” 2017. Web. 04 Mar 2021.

Vancouver:

Plavšić, Budimir R. 1. Epizootiološki i ekonomski efekti sprovođenja kontinuirane vakcinacije svinja protiv klasične kuge u Republici Srbiji. [Internet] [Thesis]. Univerzitet u Beogradu; 2017. [cited 2021 Mar 04]. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:14495/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Plavšić, Budimir R. 1. Epizootiološki i ekonomski efekti sprovođenja kontinuirane vakcinacije svinja protiv klasične kuge u Republici Srbiji. [Thesis]. Univerzitet u Beogradu; 2017. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:14495/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Univerzitet u Beogradu

13. Prodanov-Radulović, Jasna, 1972-. Uticaj kolostralnih antitela na stepen imunosti prasadi vakcinisanih protiv klasične kuge svinja.

Degree: Fakultet veterinarske medicine, 2015, Univerzitet u Beogradu

URL: https://fedorabg.bg.ac.rs/fedora/get/o:7114/bdef:Content/get

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Klinička veterina - Zarazne bolesti i epizootiologija / Clinical Veterinary Medicine - Infectious Diseases and Epizootiology

Cilj ispitivanja je bio da se ustanovi da li… (more)

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Klinička veterina - Zarazne bolesti i epizootiologija / Clinical Veterinary Medicine - Infectious Diseases and Epizootiology

Cilj ispitivanja je bio da se ustanovi da li kod prasadi poreklom od vakcinisanih krmača, posle vakcinacije sa atenuisanom i subjediničnom vakcinom, dolazi do interferencije kolostralnog imuniteta sa sintezom sopstvenih antitela i da li postvakcinalni imuni odgovor sprečava pojavu oboljenja, izlučivanje virusa i širenje klasične kuge svinja (KKS). Ogledna ispitivanja su obavljena 60 prasadi, uzrasta 45 dana (18 nevakcinisane prasadi poreklom od nevakcinisanih krmača i 42 nevakcinisana praseta poreklom od krmača vakcinisanih Kina (K)-sojem virusa KKS). Eksperimentalna ispitivanja su podeljena u dve faze: prva faza je obuhvatala ispitivanja sa primenom atenuisane (K-soj) vakcine dok je druga faza obuhvatala primenu subjedinične vakcine. U cilju utvrđivanja prisustva kolostralnih antitela u serumu prasadi, izvršeno je preliminarno uzorkovanje krvi 100 prasadi uzrasta 43 dana. Na osnovu rezultata seroloških ispitivanja (ELISA test), formirane su po tri eksperimentalne grupe, od po sedam jedinki u grupi: pozitivna grupa (utvrđeno prisustvo kolostralnih antitela), negativna grupa (nije utvrđeno prisustvo kolostralnih antitela) i treća grupa prasadi kod kojih su antitela utvrđena na granici detektabilnosti (sumnjiva grupa). U uzrastu 45 dana obavljena je vakcinacija tri grupe prasadi atenuisanom (K-soj) dok su preostale tri grupe prasadi vakcinisane i revakcinisane subjediničnom vakcinom. Četrnaest dana nakon vakcinacije K-sojem odnosno revakcinacije subjediničnom vakcinom izvršena je veštačka infekcija prasadi virulentnim sojem virusa KKS (Beker soj). Jedan dan nakon veštačke infekcije u cilju kontrole izlučivanja virusa u svaku grupu su dodana po 2 neimuna praseta, poreklom od nevakcinisanih krmača. Nakon veštačke infekcije, vršena je kontinuirana klinička opservacija jedinki i od svakog praseta je uzorkovana krv 0, 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26 i 28. dana nakon veštačke infekcije u cilju kontrole prisustva specifičnih antitela protiv virusa II KKS i viremije (ELISA test i RT-PCR)...

Advisors/Committee Members: Valčić, Miroslav, 1955-.

Subjects/Keywords: classical swine fever; colostral antibodies; interference; China-strain; subunit vaccine

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Prodanov-Radulović, Jasna, 1. (2015). Uticaj kolostralnih antitela na stepen imunosti prasadi vakcinisanih protiv klasične kuge svinja. (Thesis). Univerzitet u Beogradu. Retrieved from https://fedorabg.bg.ac.rs/fedora/get/o:7114/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Prodanov-Radulović, Jasna, 1972-. “Uticaj kolostralnih antitela na stepen imunosti prasadi vakcinisanih protiv klasične kuge svinja.” 2015. Thesis, Univerzitet u Beogradu. Accessed March 04, 2021. https://fedorabg.bg.ac.rs/fedora/get/o:7114/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Prodanov-Radulović, Jasna, 1972-. “Uticaj kolostralnih antitela na stepen imunosti prasadi vakcinisanih protiv klasične kuge svinja.” 2015. Web. 04 Mar 2021.

Vancouver:

Prodanov-Radulović, Jasna 1. Uticaj kolostralnih antitela na stepen imunosti prasadi vakcinisanih protiv klasične kuge svinja. [Internet] [Thesis]. Univerzitet u Beogradu; 2015. [cited 2021 Mar 04]. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:7114/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Prodanov-Radulović, Jasna 1. Uticaj kolostralnih antitela na stepen imunosti prasadi vakcinisanih protiv klasične kuge svinja. [Thesis]. Univerzitet u Beogradu; 2015. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:7114/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Iowa State University

14. McDaniel, Harless Alton. Brain lesions and viremia studies in swine infected with a hog cholera virus of low pathogenicity.

Degree: 1966, Iowa State University

URL: https://lib.dr.iastate.edu/rtd/3112

Subjects/Keywords: Classical swine fever; Encephalitis; Pathology

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

McDaniel, H. A. (1966). Brain lesions and viremia studies in swine infected with a hog cholera virus of low pathogenicity. (Thesis). Iowa State University. Retrieved from https://lib.dr.iastate.edu/rtd/3112

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

McDaniel, Harless Alton. “Brain lesions and viremia studies in swine infected with a hog cholera virus of low pathogenicity.” 1966. Thesis, Iowa State University. Accessed March 04, 2021. https://lib.dr.iastate.edu/rtd/3112.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

McDaniel, Harless Alton. “Brain lesions and viremia studies in swine infected with a hog cholera virus of low pathogenicity.” 1966. Web. 04 Mar 2021.

Vancouver:

McDaniel HA. Brain lesions and viremia studies in swine infected with a hog cholera virus of low pathogenicity. [Internet] [Thesis]. Iowa State University; 1966. [cited 2021 Mar 04]. Available from: https://lib.dr.iastate.edu/rtd/3112.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

McDaniel HA. Brain lesions and viremia studies in swine infected with a hog cholera virus of low pathogenicity. [Thesis]. Iowa State University; 1966. Available from: https://lib.dr.iastate.edu/rtd/3112

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Michigan State University

15. Purohit, Mohan Singh, 1924-. Population studies on five genera of intestinal bacteria of swine during normal conditions of health during artificially induced hog cholera.

Degree: PhD, 1953, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:5106

Subjects/Keywords: Classical swine fever; Intestines – Microbiology

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APA (6^th Edition):

Purohit, Mohan Singh, 1. (1953). Population studies on five genera of intestinal bacteria of swine during normal conditions of health during artificially induced hog cholera. (Doctoral Dissertation). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:5106

Chicago Manual of Style (16^th Edition):

Purohit, Mohan Singh, 1924-. “Population studies on five genera of intestinal bacteria of swine during normal conditions of health during artificially induced hog cholera.” 1953. Doctoral Dissertation, Michigan State University. Accessed March 04, 2021. http://etd.lib.msu.edu/islandora/object/etd:5106.

MLA Handbook (7^th Edition):

Purohit, Mohan Singh, 1924-. “Population studies on five genera of intestinal bacteria of swine during normal conditions of health during artificially induced hog cholera.” 1953. Web. 04 Mar 2021.

Vancouver:

Purohit, Mohan Singh 1. Population studies on five genera of intestinal bacteria of swine during normal conditions of health during artificially induced hog cholera. [Internet] [Doctoral dissertation]. Michigan State University; 1953. [cited 2021 Mar 04]. Available from: http://etd.lib.msu.edu/islandora/object/etd:5106.

Council of Science Editors:

Purohit, Mohan Singh 1. Population studies on five genera of intestinal bacteria of swine during normal conditions of health during artificially induced hog cholera. [Doctoral Dissertation]. Michigan State University; 1953. Available from: http://etd.lib.msu.edu/islandora/object/etd:5106

Kansas State University

16. Carlson, Jolene Christine. Dynamics of protection against virulent challenge in swine vaccinated with attenuated African swine fever viruses.

Degree: PhD, Department of Diagnostic Medicine/Pathobiology, 2016, Kansas State University

URL: http://hdl.handle.net/2097/34143

► African swine fever (ASF) is a lethal hemorrhagic disease of swine caused by a double-stranded DNA virus. ASFV is endemic in Sardinia and Saharan Africa… (more)

Subjects/Keywords: African swine fever virus; Interferon gamma; Attenuated virus; Correlates of protection; Vaccination; 9GL

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Carlson, J. C. (2016). Dynamics of protection against virulent challenge in swine vaccinated with attenuated African swine fever viruses. (Doctoral Dissertation). Kansas State University. Retrieved from http://hdl.handle.net/2097/34143

Chicago Manual of Style (16^th Edition):

Carlson, Jolene Christine. “Dynamics of protection against virulent challenge in swine vaccinated with attenuated African swine fever viruses.” 2016. Doctoral Dissertation, Kansas State University. Accessed March 04, 2021. http://hdl.handle.net/2097/34143.

MLA Handbook (7^th Edition):

Carlson, Jolene Christine. “Dynamics of protection against virulent challenge in swine vaccinated with attenuated African swine fever viruses.” 2016. Web. 04 Mar 2021.

Vancouver:

Carlson JC. Dynamics of protection against virulent challenge in swine vaccinated with attenuated African swine fever viruses. [Internet] [Doctoral dissertation]. Kansas State University; 2016. [cited 2021 Mar 04]. Available from: http://hdl.handle.net/2097/34143.

Council of Science Editors:

Carlson JC. Dynamics of protection against virulent challenge in swine vaccinated with attenuated African swine fever viruses. [Doctoral Dissertation]. Kansas State University; 2016. Available from: http://hdl.handle.net/2097/34143

Freie Universität Berlin

17. Faust, Anja. A comparative study of vaccination with lyophilised C-strain and chimeric pestiviruses.

Degree: 2008, Freie Universität Berlin

URL: http://dx.doi.org/10.17169/refubium-10484

► This thesis deals with the advancement of oral immunization of wild boar, focussing on the creation of a new bait formulation. The basic objective of… (more)

▼ This thesis deals with the advancement of oral immunization of wild boar, focussing on the creation of a new bait formulation. The basic objective of oral immunization is to enhance herd immunity and to eliminate the CSF pathogen within a short time frame. Higher bait uptake rates in gruntlings would on one hand lead to an increase of the seroprevalence rate in the wild boar population and on the other hand to a reduction of the number of susceptible animals. This would permit an even more effective control of CSF in the wild boar population. The uptake studies performed with domestic pigs and wild boar described in this exposition revealed, that gruntlings below four months of age only played with the baits and showed an incomplete uptake. By four months of age, the animals began to develop an active bait uptake initially showing a preference for the small baits (1.8 cm diameter). By the age of five to six months, the animals began to pick up the spheroidal 3 cm bait. The 3 cm bait was taken as a model for the creation of a new box vaccine container. In order to incorporate a sufficient amount of virus antigen into the bait, the vaccine ( C -strain/CP7_E2alf) was lyophilised and filled into hard gelatine capsules which were then covered with the maize bait masse. Following investigations on the bait uptake, the lyophilised vaccine (we used the conventional C -strain and the chimeric pestivirus CP7_E2alf) was examined for its stability in comparison to the liquid formulation under different environmental conditions. It could be shown, that both vaccines are much more stable in the lyophilised than in the liquid form (p < 0,05). Due to the higher stability of lyophilised vaccine at temperatures over 20°C, the new formulation represents an improvement and is especially suitable for immunization campaigns carried out at higher environmental temperatures (in summer or in warmer regions). In the first part of the animal experiments carried out for the present thesis, the efficacy of the bait formulation containing lyophilised C -strain virus was studied. After administration of the spheroidal vaccine baits to wild boar and domestic pigs followed by an infection with a low dose of CSFV strain Alfort 187 , all vaccinated domestic pigs and wild boar were protected from a CSF infection and we were neither able to isolate challenge virus from BC nor from nasal mucous, eye fluid, saliva or faeces. In a second confirmatory trial, pigs were immunised with lyophilised C -strain and the spheroidal 3 cm bait and were subsequently subjected to a challenge infection with 1,000 TCID50/ml. Again, the animals, which had picked up the bait completely, were protected from a lethal CSFV infection. Neither viremia nor virus shedding could be detected. The pigs developed high neutralising antibody titres. To conclude, the new bait- formulation consisting of: a) a smaller bait (d = 3 cm) b) a hard gelatine capsule with snap-lock and c) lyophilised C -virus is able to protect pigs against a severe CSF infection and simultaneously prevent… Advisors/Committee Members: n (gender), Univ.- Prof. Dr. H. Ludwig (firstReferee), Dir. u. Prof. Dr. V. Kaden (furtherReferee), Prof. Dr. K. H. Lahrmann (furtherReferee).

Subjects/Keywords: classical swine fever virus; wild pigs; swine fever; baits; immunization; oral vaccination; 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Faust, A. (2008). A comparative study of vaccination with lyophilised C-strain and chimeric pestiviruses. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-10484

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Faust, Anja. “A comparative study of vaccination with lyophilised C-strain and chimeric pestiviruses.” 2008. Thesis, Freie Universität Berlin. Accessed March 04, 2021. http://dx.doi.org/10.17169/refubium-10484.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Faust, Anja. “A comparative study of vaccination with lyophilised C-strain and chimeric pestiviruses.” 2008. Web. 04 Mar 2021.

Vancouver:

Faust A. A comparative study of vaccination with lyophilised C-strain and chimeric pestiviruses. [Internet] [Thesis]. Freie Universität Berlin; 2008. [cited 2021 Mar 04]. Available from: http://dx.doi.org/10.17169/refubium-10484.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Faust A. A comparative study of vaccination with lyophilised C-strain and chimeric pestiviruses. [Thesis]. Freie Universität Berlin; 2008. Available from: http://dx.doi.org/10.17169/refubium-10484

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

18. Burton, Mollie K. Identification of cross-reactive epitope regions of bovine viral diarrhea virus and classical swine fever virus glycoproteins.

Degree: MS, Department of Diagnostic Medicine/Pathobiology, 2016, Kansas State University

URL: http://hdl.handle.net/2097/34530

► Pestiviruses such as classical swine fever virus (CSFV) and bovine viral diarrhea virus (BVDV) are some of the most economically important livestock diseases in the… (more)

▼ Pestiviruses such as classical swine fever virus (CSFV) and bovine viral diarrhea virus (BVDV) are some of the most economically important livestock diseases in the world. The antigenic similarities between members of the pestivirus genus allow for both BVDV and CSFV to infect swine. Infections with heterologous pestiviruses in swine can interfere with diagnostic tests for CSFV. The identification of cross-reactive and cross-neutralizing epitopes between CSFV and BVDV for the development of improved diagnostics and vaccines that allow for the differentiation of infected animals from vaccinated animals (DIVAs) are necessary to accurately detect and control CSFV. The overall goal of this research was to identify epitope regions recognized by antibodies that can differentiate between CSFV and BVDV. The approach was to use serum neutralization assays to confirm the presence of neutralizing antibodies to BVDV in swine serum collected from animals immunized with one of three separate Alphavirus vaccine constructs: BVDV-1b, CSFV E2, and CSFV E[superscript]rns. Results showed that animals immunized with the Alphavirus BVDV-1b construct had high neutralizing titers against BVDV-1a and animals immunized with Alphavirus CSFV E2 and E[superscript]rns constructs had low, but detectable, neutralizing activity. Polypeptide fragments of CSFV and BVDV E2 were then expressed in E. coli and purified using affinity chromatography. Serum from a pig immunized with the CSFV E2 Alphavirus construct was tested against two fragments of CSFV E2, 2/4 and 4/4, and four fragments BVDV E2, 1/4, 2/4, 3/4, and 4/4, using western blot analysis. Reactivity to fragments CSFV E2 2/4 and 4/4 and BVDV E2 1/4 and 4/4 was observed. The results of this study identified CSFV amino acid positions 774 through 857 and BVDV amino acid positions 783 through 872 as the regions that contain the epitopes recognized by cross-reactive antibodies between BVDV and CSFV E2. These results provide more specific sequence regions to improve CSFV diagnostic assays and DIVA vaccines. Advisors/Committee Members: Raymond R. R. Rowland.

Subjects/Keywords: Immunology; Pestivirus; Epitope Mapping; Animal Diseases; Classical Swine Fever Virus; Bovine Viral Diarrhea Virus

…Classical Swine Fever Virus and Bovine Viral Diarrhea Virus Introduction Pestiviruses such as… …classical swine fever virus (CSFV) and bovine viral diarrhea virus (BVDV) are… …x29;. Virus Economic Impact CSFV, also known as hog cholera, swine fever, peste du porc… …such as African swine fever virus (ASFV), porcine dermatitis and nephropathy… …Hepacivirus, Pestivirus, and Pegivirus. Species such as yellow fever virus, West Nile virus…

9 more images…

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Burton, M. K. (2016). Identification of cross-reactive epitope regions of bovine viral diarrhea virus and classical swine fever virus glycoproteins. (Masters Thesis). Kansas State University. Retrieved from http://hdl.handle.net/2097/34530

Chicago Manual of Style (16^th Edition):

Burton, Mollie K. “Identification of cross-reactive epitope regions of bovine viral diarrhea virus and classical swine fever virus glycoproteins.” 2016. Masters Thesis, Kansas State University. Accessed March 04, 2021. http://hdl.handle.net/2097/34530.

MLA Handbook (7^th Edition):

Burton, Mollie K. “Identification of cross-reactive epitope regions of bovine viral diarrhea virus and classical swine fever virus glycoproteins.” 2016. Web. 04 Mar 2021.

Vancouver:

Burton MK. Identification of cross-reactive epitope regions of bovine viral diarrhea virus and classical swine fever virus glycoproteins. [Internet] [Masters thesis]. Kansas State University; 2016. [cited 2021 Mar 04]. Available from: http://hdl.handle.net/2097/34530.

Council of Science Editors:

Burton MK. Identification of cross-reactive epitope regions of bovine viral diarrhea virus and classical swine fever virus glycoproteins. [Masters Thesis]. Kansas State University; 2016. Available from: http://hdl.handle.net/2097/34530

19. Marta Maria Nery Farias da Silva. Diagnóstico da peste suína clássica nas regiões norte e nordeste do Brasil no período de 1999 a 2009.

Degree: 2012, Universidade Federal Rural de Pernambuco

URL: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1467

►

O vírus da peste suína clássica causa doença altamente contagiosa em suínos domésticos e selvagens, caracterizada por levar a grandes perdas econômicas, tanto para a… (more)

▼

O vírus da peste suína clássica causa doença altamente contagiosa em suínos domésticos e selvagens, caracterizada por levar a grandes perdas econômicas, tanto para a suinocultura de grande porte como também para os pequenos produtores. A doença pode se apresentar de forma aguda, crônica, tardia, assintomática ou persistente, que dependem da virulência da cepa, idade do animal, estado imunológico, período de gestação. A doença é de notificação obrigatória, e as medidas de controle estão listadas no Programa Nacional de Sanidade Suidea do Ministério da Agricultura, Pecuária e do Abastecimento. Quanto à divisão sanitária atualmente adotada, o Brasil conta com uma zona considerada com livre de peste suína clássica que é constituída pelos principais estados produtores de suínos e pelas fronteiras de expansão da atividade e uma zona não livre, que engloba a maioria dos estados das regiões Norte e Nordeste do Brasil. Fora da área considerada livre focos de peste suína clássica continuam acontecendo de forma esporádica, porém a proposta do Ministério de Agricultura Pecuária e Abastecimento é erradicar a enfermidade em todo o território nacional. O diagnóstico de suspeitas da infecção pode ser feito através do isolamento e identificação viral em cultivos celulares, considerado o teste ouro, por meio das técnicas de imunofluorescência e imunoperoxidase. Foram analisadas por estas técnicas no Laboratório Nacional Agropecuário em Pernambuco amostras de órgãos e sangue de 149 suínos com suspeita de PSC, no período compreendido entre 1999 e 2009, provenientes dos estados do Pará e Amapá da região norte e Maranhão, Ceará, Rio Grande do Norte, Paraíba e Pernambuco da região nordeste. Dos suínos analisados, 51 estavam infectados com o vírus da peste suína clássica. Nos achados clínicos e de necropsia eram predominantes de alterações hemorrágicas, típicas da forma clássica da doença. As criações afetadas eram predominantemente de baixo nível de tecnificação. Os resultados obtidos evidenciaram que a presença de animais positivos é alta, estando o agente presente na maioria dos Estados das regiões Nordeste e Norte, e que a aplicação de medidas preventivas a campo de forma efetiva podem diminuir ou evitar o aparecimento de casos e focos da enfermidade.

The classical swine fever virus causes a highly contagious disease in domestic and wild pigs, characterized by leading to great economic losses, for both large and small farming. The disease may present as acute, chronic, delayed, or persistent asymptomatic, which depend on the virulence of the strain, animal age, immune status, gestation period. The disease is notifiable and control measures are listed in the National Program to Swine Health from Ministry of Agriculture, Livestock and Supply. Brazil has an area considered as free of classical swine fever which is composed of the major part of states and non-free zone, which has the majority of states in the North and Northeast Brazil. Outside the area considered free of classical swine fever outbreaks continue to occur sporadically,…

Advisors/Committee Members: Roberto Soares de Castro.

Subjects/Keywords: Immunofluorescence; Imunofluorescência; Imunoperoxidase; Classical swine fever; Peste suína clássica; MEDICINA VETERINARIA; Immunoperoxidase

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Silva, M. M. N. F. d. (2012). Diagnóstico da peste suína clássica nas regiões norte e nordeste do Brasil no período de 1999 a 2009. (Thesis). Universidade Federal Rural de Pernambuco. Retrieved from http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1467

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Silva, Marta Maria Nery Farias da. “Diagnóstico da peste suína clássica nas regiões norte e nordeste do Brasil no período de 1999 a 2009.” 2012. Thesis, Universidade Federal Rural de Pernambuco. Accessed March 04, 2021. http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1467.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Silva, Marta Maria Nery Farias da. “Diagnóstico da peste suína clássica nas regiões norte e nordeste do Brasil no período de 1999 a 2009.” 2012. Web. 04 Mar 2021.

Vancouver:

Silva MMNFd. Diagnóstico da peste suína clássica nas regiões norte e nordeste do Brasil no período de 1999 a 2009. [Internet] [Thesis]. Universidade Federal Rural de Pernambuco; 2012. [cited 2021 Mar 04]. Available from: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1467.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Silva MMNFd. Diagnóstico da peste suína clássica nas regiões norte e nordeste do Brasil no período de 1999 a 2009. [Thesis]. Universidade Federal Rural de Pernambuco; 2012. Available from: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1467

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

20. Marta Maria Nery Farias da Silva. Diagnóstico da peste suína clássica nas regiões norte e nordeste do Brasil no período de 1999 a 2009.

Degree: 2012, Universidade Federal Rural de Pernambuco

URL: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1467

►

O vírus da peste suína clássica causa doença altamente contagiosa em suínos domésticos e selvagens, caracterizada por levar a grandes perdas econômicas, tanto para a… (more)

▼

O vírus da peste suína clássica causa doença altamente contagiosa em suínos domésticos e selvagens, caracterizada por levar a grandes perdas econômicas, tanto para a suinocultura de grande porte como também para os pequenos produtores. A doença pode se apresentar de forma aguda, crônica, tardia, assintomática ou persistente, que dependem da virulência da cepa, idade do animal, estado imunológico, período de gestação. A doença é de notificação obrigatória, e as medidas de controle estão listadas no Programa Nacional de Sanidade Suidea do Ministério da Agricultura, Pecuária e do Abastecimento. Quanto à divisão sanitária atualmente adotada, o Brasil conta com uma zona considerada com livre de peste suína clássica que é constituída pelos principais estados produtores de suínos e pelas fronteiras de expansão da atividade e uma zona não livre, que engloba a maioria dos estados das regiões Norte e Nordeste do Brasil. Fora da área considerada livre focos de peste suína clássica continuam acontecendo de forma esporádica, porém a proposta do Ministério de Agricultura Pecuária e Abastecimento é erradicar a enfermidade em todo o território nacional. O diagnóstico de suspeitas da infecção pode ser feito através do isolamento e identificação viral em cultivos celulares, considerado o teste ouro, por meio das técnicas de imunofluorescência e imunoperoxidase. Foram analisadas por estas técnicas no Laboratório Nacional Agropecuário em Pernambuco amostras de órgãos e sangue de 149 suínos com suspeita de PSC, no período compreendido entre 1999 e 2009, provenientes dos estados do Pará e Amapá da região norte e Maranhão, Ceará, Rio Grande do Norte, Paraíba e Pernambuco da região nordeste. Dos suínos analisados, 51 estavam infectados com o vírus da peste suína clássica. Nos achados clínicos e de necropsia eram predominantes de alterações hemorrágicas, típicas da forma clássica da doença. As criações afetadas eram predominantemente de baixo nível de tecnificação. Os resultados obtidos evidenciaram que a presença de animais positivos é alta, estando o agente presente na maioria dos Estados das regiões Nordeste e Norte, e que a aplicação de medidas preventivas a campo de forma efetiva podem diminuir ou evitar o aparecimento de casos e focos da enfermidade.

The classical swine fever virus causes a highly contagious disease in domestic and wild pigs, characterized by leading to great economic losses, for both large and small farming. The disease may present as acute, chronic, delayed, or persistent asymptomatic, which depend on the virulence of the strain, animal age, immune status, gestation period. The disease is notifiable and control measures are listed in the National Program to Swine Health from Ministry of Agriculture, Livestock and Supply. Brazil has an area considered as free of classical swine fever which is composed of the major part of states and non-free zone, which has the majority of states in the North and Northeast Brazil. Outside the area considered free of classical swine fever outbreaks continue to occur sporadically,…

Advisors/Committee Members: Roberto Soares de Castro.

Subjects/Keywords: Peste suína clássica; Imunofluorescência; Imunoperoxidase; MEDICINA VETERINARIA; Classical swine fever; Immunofluorescence; Immunoperoxidase

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Silva, M. M. N. F. d. (2012). Diagnóstico da peste suína clássica nas regiões norte e nordeste do Brasil no período de 1999 a 2009. (Thesis). Universidade Federal Rural de Pernambuco. Retrieved from http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1467

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Silva, Marta Maria Nery Farias da. “Diagnóstico da peste suína clássica nas regiões norte e nordeste do Brasil no período de 1999 a 2009.” 2012. Thesis, Universidade Federal Rural de Pernambuco. Accessed March 04, 2021. http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1467.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Silva, Marta Maria Nery Farias da. “Diagnóstico da peste suína clássica nas regiões norte e nordeste do Brasil no período de 1999 a 2009.” 2012. Web. 04 Mar 2021.

Vancouver:

Silva MMNFd. Diagnóstico da peste suína clássica nas regiões norte e nordeste do Brasil no período de 1999 a 2009. [Internet] [Thesis]. Universidade Federal Rural de Pernambuco; 2012. [cited 2021 Mar 04]. Available from: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1467.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Silva MMNFd. Diagnóstico da peste suína clássica nas regiões norte e nordeste do Brasil no período de 1999 a 2009. [Thesis]. Universidade Federal Rural de Pernambuco; 2012. Available from: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=1467

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Iowa State University

21. Cassidy, Delmar Ronald. The hematology of hog cholera.

Degree: 1970, Iowa State University

URL: https://lib.dr.iastate.edu/rtd/4216

Subjects/Keywords: Classical swine fever; Veterinary hematology; Pathology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Cassidy, D. R. (1970). The hematology of hog cholera. (Thesis). Iowa State University. Retrieved from https://lib.dr.iastate.edu/rtd/4216

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Cassidy, Delmar Ronald. “The hematology of hog cholera.” 1970. Thesis, Iowa State University. Accessed March 04, 2021. https://lib.dr.iastate.edu/rtd/4216.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Cassidy, Delmar Ronald. “The hematology of hog cholera.” 1970. Web. 04 Mar 2021.

Vancouver:

Cassidy DR. The hematology of hog cholera. [Internet] [Thesis]. Iowa State University; 1970. [cited 2021 Mar 04]. Available from: https://lib.dr.iastate.edu/rtd/4216.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Cassidy DR. The hematology of hog cholera. [Thesis]. Iowa State University; 1970. Available from: https://lib.dr.iastate.edu/rtd/4216

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Virginia Tech

22. Bell, Wilson B. Modification of the hog cholera virus.

Degree: PhD, Animal Pathology, 1952, Virginia Tech

URL: http://hdl.handle.net/10919/76208

► Rabbit Passage of the Virus The hog cholera virus was carried through six alternate passages from pig to rabbit and then top five serial passages… (more)

Subjects/Keywords: LD5655.V856 1952.B444; Classical swine fever; Swine – Diseases

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Bell, W. B. (1952). Modification of the hog cholera virus. (Doctoral Dissertation). Virginia Tech. Retrieved from http://hdl.handle.net/10919/76208

Chicago Manual of Style (16^th Edition):

Bell, Wilson B. “Modification of the hog cholera virus.” 1952. Doctoral Dissertation, Virginia Tech. Accessed March 04, 2021. http://hdl.handle.net/10919/76208.

MLA Handbook (7^th Edition):

Bell, Wilson B. “Modification of the hog cholera virus.” 1952. Web. 04 Mar 2021.

Vancouver:

Bell WB. Modification of the hog cholera virus. [Internet] [Doctoral dissertation]. Virginia Tech; 1952. [cited 2021 Mar 04]. Available from: http://hdl.handle.net/10919/76208.

Council of Science Editors:

Bell WB. Modification of the hog cholera virus. [Doctoral Dissertation]. Virginia Tech; 1952. Available from: http://hdl.handle.net/10919/76208

Michigan State University

23. Waxler, Glenn Lee. The influence of some nutritional factors on experimental hog-cholera infection.

Degree: MS, 1959, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:13771

Subjects/Keywords: Classical swine fever; Swine – Feeding and feeds

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APA (6^th Edition):

Waxler, G. L. (1959). The influence of some nutritional factors on experimental hog-cholera infection. (Masters Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:13771

Chicago Manual of Style (16^th Edition):

Waxler, Glenn Lee. “The influence of some nutritional factors on experimental hog-cholera infection.” 1959. Masters Thesis, Michigan State University. Accessed March 04, 2021. http://etd.lib.msu.edu/islandora/object/etd:13771.

MLA Handbook (7^th Edition):

Waxler, Glenn Lee. “The influence of some nutritional factors on experimental hog-cholera infection.” 1959. Web. 04 Mar 2021.

Vancouver:

Waxler GL. The influence of some nutritional factors on experimental hog-cholera infection. [Internet] [Masters thesis]. Michigan State University; 1959. [cited 2021 Mar 04]. Available from: http://etd.lib.msu.edu/islandora/object/etd:13771.

Council of Science Editors:

Waxler GL. The influence of some nutritional factors on experimental hog-cholera infection. [Masters Thesis]. Michigan State University; 1959. Available from: http://etd.lib.msu.edu/islandora/object/etd:13771

University of Alberta

24. Reza, Md Salman. Combined Assembly of Metagenomic Libraries from The Faecal Samples of IBD and PSC Patients Allowed The Identification of African Swine Fever Virus-like Sequences.

Degree: MS, Department of Medicine, 2015, University of Alberta

URL: https://era.library.ualberta.ca/files/vt150m842

► Metagenomics is an emerging discipline to explore microbial diversity in clinical samples, independent of the limitations of cell cultures. This method is widely accepted as… (more)

▼ Metagenomics is an emerging discipline to explore microbial diversity in clinical samples, independent of the limitations of cell cultures. This method is widely accepted as a modern technique to detect novel viruses in clinical and environmental samples and has the potential to contribute to the identification of unknown etiological agents causing diseases. This thesis utilizes the combined assembly approach on deep sequencing data in search for novel viral populations in clinical samples of patients diagnosed with inflammatory bowel disease (IBD) and primary sclerosing cholangitis (PSC), which is an extraintestinal manifestation of IBD. In this study, twelve mammalian viral sequences and other plant, bird and insect viral sequences were found. Among the viral sequences, we have detected many sequences of African swine fever like virus (ASFLV) in the IBD and PSC patients after the combined assembly approach but not in the initial metagenomics data sets of the assembly from the individual patient. Interestingly, the ASFLV sequences showed similarity to thirty-nine genes along the ASFV genome, but only 38-62% identity at the amino acid level, suggesting that they are related by distinct sequences. Phylogenetic analyses positioned the ASFLV sequences in a clade different from those clustering ASFV and that was consistent for the topoisomerase, capsid and helicase genes. Furthermore, nested PCR confirmed the presence of ASFLV sequences in one ulcerative colitis and PSC patients for multiple loci including the capsid, helicase and origin binding proteins. Thus, we report for the first time the presence of ASFLV sequences in human clinical samples in North America. This study also investigates the suitability of several viral enrichment methods to isolate viruses from clinical samples before performing metagenomics. The detection of ASFLV sequences was possible only after adopting the combined assembly approach, which enabled the identification of a novel virus sequences and improved the overall identification of viruses in the metagenomic libraries.

Subjects/Keywords: Combined assembly; Next generation sequencing; Metagenomic libraries; Viral metagenomics; African swine fever virus-like sequences

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APA (6^th Edition):

Reza, M. S. (2015). Combined Assembly of Metagenomic Libraries from The Faecal Samples of IBD and PSC Patients Allowed The Identification of African Swine Fever Virus-like Sequences. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/vt150m842

Chicago Manual of Style (16^th Edition):

Reza, Md Salman. “Combined Assembly of Metagenomic Libraries from The Faecal Samples of IBD and PSC Patients Allowed The Identification of African Swine Fever Virus-like Sequences.” 2015. Masters Thesis, University of Alberta. Accessed March 04, 2021. https://era.library.ualberta.ca/files/vt150m842.

MLA Handbook (7^th Edition):

Reza, Md Salman. “Combined Assembly of Metagenomic Libraries from The Faecal Samples of IBD and PSC Patients Allowed The Identification of African Swine Fever Virus-like Sequences.” 2015. Web. 04 Mar 2021.

Vancouver:

Reza MS. Combined Assembly of Metagenomic Libraries from The Faecal Samples of IBD and PSC Patients Allowed The Identification of African Swine Fever Virus-like Sequences. [Internet] [Masters thesis]. University of Alberta; 2015. [cited 2021 Mar 04]. Available from: https://era.library.ualberta.ca/files/vt150m842.

Council of Science Editors:

Reza MS. Combined Assembly of Metagenomic Libraries from The Faecal Samples of IBD and PSC Patients Allowed The Identification of African Swine Fever Virus-like Sequences. [Masters Thesis]. University of Alberta; 2015. Available from: https://era.library.ualberta.ca/files/vt150m842

Kansas State University

25. Petrovan, Vlad. Antigenic characterization of African swine fever virus (ASFV) p30 and p54 proteins.

Degree: PhD, Department of Diagnostic Medicine/Pathobiology, 2019, Kansas State University

URL: http://hdl.handle.net/2097/39614

► African swine fever (ASF) is a highly contagious and lethal viral disease of swine with significant socio-economic impact in the developed and developing world. In… (more)

▼ African swine fever (ASF) is a highly contagious and lethal viral disease of swine with significant socio-economic impact in the developed and developing world. In the absence of a vaccine, recent outbreaks in Europe and Asia have drawn interest in developing diagnostics tools that are critical for early detection and implementation of strict biosafety measures. African swine fever virus (ASFV) has a complex organization, containing more than 100 proteins, including those with a structural role and enzymes that are packed in the virus core for use in early infection. Among the structural proteins, p30 and p54 are also highly immunogenic, representing serological candidates for conducting ASF detection and surveillance. Production of monoclonal antibodies (mAbs) and recombinant proteins will help characterize the antigenic regions which, in turn, will lead to the development of novel diagnostic tests against this disease. In this study, a panel of mAbs was generated against recombinant p54 and p30. First, we developed a screening methodology for the resulting hybridomas using enzyme linked immunosorbent assay (ELISA) and confirmatory immunofluorescence assay (IFA) on ASFV infected cells. Our results identified five mAbs against p54 and three mAbs against p30 which were positive on both assays. Based on the screening methodology and criteria, we further characterized our mAbs by immunoprecipitation, Western blot analysis, ELISA, and immunohistochemistry (IHC) in a wide variety of tissues collected from ASFV-infected pigs. Second, the epitopes recognized by those mAbs were identified using recombinant polypeptide fragments expressed in bacteria or mammalian cells and oligopeptides. These assays identified several linear epitopes which were also recognized by sera from ASFV-infected pigs. Interestingly, the anti-p30 mAbs also recognized a region that has similar characteristics similar to an intrinsically disordered protein (IDP). Third, we evaluated the efficacy of our generated mAbs in a highly sensitive blocking ELISA, using known positive and negative serum samples. The results presented in this thesis provide valuable tools for improving ASFV diagnostics, surveillance, and vaccine development. Advisors/Committee Members: Raymond R. R. Rowland.

Subjects/Keywords: African swine fever virus; monoclonal antibodies; p54; p30; diagnostic tests; epitope mapping

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Petrovan, V. (2019). Antigenic characterization of African swine fever virus (ASFV) p30 and p54 proteins. (Doctoral Dissertation). Kansas State University. Retrieved from http://hdl.handle.net/2097/39614

Chicago Manual of Style (16^th Edition):

Petrovan, Vlad. “Antigenic characterization of African swine fever virus (ASFV) p30 and p54 proteins.” 2019. Doctoral Dissertation, Kansas State University. Accessed March 04, 2021. http://hdl.handle.net/2097/39614.

MLA Handbook (7^th Edition):

Petrovan, Vlad. “Antigenic characterization of African swine fever virus (ASFV) p30 and p54 proteins.” 2019. Web. 04 Mar 2021.

Vancouver:

Petrovan V. Antigenic characterization of African swine fever virus (ASFV) p30 and p54 proteins. [Internet] [Doctoral dissertation]. Kansas State University; 2019. [cited 2021 Mar 04]. Available from: http://hdl.handle.net/2097/39614.

Council of Science Editors:

Petrovan V. Antigenic characterization of African swine fever virus (ASFV) p30 and p54 proteins. [Doctoral Dissertation]. Kansas State University; 2019. Available from: http://hdl.handle.net/2097/39614

Universiteit Utrecht

26. Klinkenberg, Dieudonné. Mathematical epidemiology and the control of classical swine fever virus.

Degree: 2003, Universiteit Utrecht

URL: http://dspace.library.uu.nl:8080/handle/1874/301

► The thesis describes epidemiological research carried out to improve the control of classical swine fever virus (CSFV) epidemics. First, control measures and strategies are investigated… (more)

▼ The thesis describes epidemiological research carried out to improve the control of classical swine fever virus (CSFV) epidemics. First, control measures and strategies are investigated in order to enable quick and adequate action upon CSFV detection. CSFV transmission experiments are described, as well as a mathematical model of CSFV transmission between herds, both used to assess the effectiveness of the E2 subunit marker vaccines with respect to CSFV transmission. Quantification of the effectiveness was done with the basic reproduction ratio Ri (Rh), defined as the number of animals (herds) that is infected by one typical infectious animal (herd) in a completely susceptible population. The transmission experiments pointed out that Ri decreases to below the threshold value 1 as of three weeks after vaccination until at least six months after vaccination. Already one week after vaccination of a pig herd, virus entry will lead to only minor outbreaks. It appeared that the presence of maternal antibodies at the time of vaccination may reduce the antibody levels at later age, but these lower levels still keep Ri below 1. Because vertical transmission is not completely blocked by the vaccine, persistently infected piglets might be born on vaccinated herds. These herds cannot be clinically detected and might thus be a risk for further virus spread. Detection will be possible if some animals, e.g. the breeding sows, on those herds remain unvaccinated. Whether that would lead to an effective control strategy was tested in a mathematical model of CSFV transmission. The model was based on the Dutch CSFV epidemic of 1997/1998, with a moderately virulent virus strain in a pig dense area with relatively many multiplier herds. The model results point out that an effective control strategy (Rh < 1) requires a complete prohibition of transport of unvaccinated animals. Moreover, in addition to the control measures that are obliged by EU legislation (like the tracing of infectious contacts and hygiene measures), the virus transmission between herds should be halved, e.g. by vaccinating 50% of all pig herds. If all animals but the breeding sows would be vaccinated, the demands for a successful control strategy are well met. In addition to the investigation of control measures and strategies, a tool was tested, which had been developed to analyse the effectiveness of the control strategy in an ongoing epidemic. The tool was designed to use data of an ongoing epidemic for estimation of Rh and the number of infected, yet undetected herds. The only data needed for the calculations are the numbers of detected herds in each week of the epidemic. Unfortunately, the only result the model could generate was whether Rh was smaller or larger than 1. Further mathematical research is needed to understand the shortcomings. Until then, some extra data might be used, e.g. an estimate of the number of infected herds at the day of the first detection, or an estimate of the average time between infection of a herd and detection.

Subjects/Keywords: Diergeneeskunde; classical swine fever virus; infectious disease; subunit vaccine; veterinary epidemiology; mathematical model; transmission experiment; basic reproduction ratio

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Klinkenberg, D. (2003). Mathematical epidemiology and the control of classical swine fever virus. (Doctoral Dissertation). Universiteit Utrecht. Retrieved from http://dspace.library.uu.nl:8080/handle/1874/301

Chicago Manual of Style (16^th Edition):

Klinkenberg, Dieudonné. “Mathematical epidemiology and the control of classical swine fever virus.” 2003. Doctoral Dissertation, Universiteit Utrecht. Accessed March 04, 2021. http://dspace.library.uu.nl:8080/handle/1874/301.

MLA Handbook (7^th Edition):

Klinkenberg, Dieudonné. “Mathematical epidemiology and the control of classical swine fever virus.” 2003. Web. 04 Mar 2021.

Vancouver:

Klinkenberg D. Mathematical epidemiology and the control of classical swine fever virus. [Internet] [Doctoral dissertation]. Universiteit Utrecht; 2003. [cited 2021 Mar 04]. Available from: http://dspace.library.uu.nl:8080/handle/1874/301.

Council of Science Editors:

Klinkenberg D. Mathematical epidemiology and the control of classical swine fever virus. [Doctoral Dissertation]. Universiteit Utrecht; 2003. Available from: http://dspace.library.uu.nl:8080/handle/1874/301

University of Connecticut

27. Wang, Yuxiang. Conferring DIVA Capability to a Commercially-Available CSFV ELISA: A Double-Competition Approach.

Degree: MS, Pathobiology, 2018, University of Connecticut

URL: https://opencommons.uconn.edu/gs_theses/1195

Subjects/Keywords: Classical swine fever virus; competition ELISA; live-attenuated marker vaccine; DIVA test; baculovirus/insect cell system

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Wang, Y. (2018). Conferring DIVA Capability to a Commercially-Available CSFV ELISA: A Double-Competition Approach. (Masters Thesis). University of Connecticut. Retrieved from https://opencommons.uconn.edu/gs_theses/1195

Chicago Manual of Style (16^th Edition):

Wang, Yuxiang. “Conferring DIVA Capability to a Commercially-Available CSFV ELISA: A Double-Competition Approach.” 2018. Masters Thesis, University of Connecticut. Accessed March 04, 2021. https://opencommons.uconn.edu/gs_theses/1195.

MLA Handbook (7^th Edition):

Wang, Yuxiang. “Conferring DIVA Capability to a Commercially-Available CSFV ELISA: A Double-Competition Approach.” 2018. Web. 04 Mar 2021.

Vancouver:

Wang Y. Conferring DIVA Capability to a Commercially-Available CSFV ELISA: A Double-Competition Approach. [Internet] [Masters thesis]. University of Connecticut; 2018. [cited 2021 Mar 04]. Available from: https://opencommons.uconn.edu/gs_theses/1195.

Council of Science Editors:

Wang Y. Conferring DIVA Capability to a Commercially-Available CSFV ELISA: A Double-Competition Approach. [Masters Thesis]. University of Connecticut; 2018. Available from: https://opencommons.uconn.edu/gs_theses/1195

Freie Universität Berlin

28. Tischer, Annika. Characterization of virulence of CSFV isolates originating from wild boar.

Degree: 2007, Freie Universität Berlin

URL: http://dx.doi.org/10.17169/refubium-9116

► The purpose of this study was to characterize the virulence of 3 CSFV field isolates obtained from wild boar in the 1990 s using in… (more)

▼ The purpose of this study was to characterize the virulence of 3 CSFV field isolates obtained from wild boar in the 1990 s using in vivo and in vitro methods. The isolates belong to genotypes 2.3 Rostock (2 isolates from Mecklenburg-Western Pomerania) and 2.3 Guestrow (1 isolate from Brandenburg). A special focus of this work was to validate in vitro methods for their suitability to characterize the virulence of different CSFV strains. Infection experiments with each CSFV isolate were carried out using both, domestic pigs and wild boars, to elucidate the influence of host factors and species on clinical outcome and etiopathology. A virulence score for the respective CSFV isolate was calculated for every single animal as well as for the particular species of swine due to clinical course and severity of the virus infection. Independently of the applied CSFV isolate all infected domestic pigs showed a subacute etiopathology and a lethal outcome of the disease. All 3 tested CSFV field isolates proved to be highly virulent for the infected domestic pigs. In contrast wild boars partially showed a less homogenous clinical outcome. Especially in one of the wild boars the disease took a chronic course with viraemia and virus shedding during the entire experiment. Due to the more variable etiopathology the examined CSFV isolates were classified as moderately virulent for wild boars. Potential reasons for the differences in virulence scores of the tested virus isolates observed between individual wild boars and in comparison with domestic pigs are elucidated. Furthermore, the relevance of chronic CSFV infections in wild boars for the epidemiology of CSF is discussed. Taken together the results emphasize the impact of host factors for the outcome of a CSFV infection. Experiments for the in vitro characterization of CSFV additionally included several older isolates of genotype 1.1 representing different virulence scores as well as another field isolate from wild boar belonging to genotype 2.3. The latter proved to be low virulent in experimentally infected wild boars. One-step growth curves revealed a distinct correlation between in vitro multiplication and genotype of the tested CSFV isolates. On the other hand the analysed parameters showed no association to virulence of the respective viruses. Furthermore, glycoprotein E2 expression also appeared to depend on the genotype of the respective CSFV, but not on its virulence. Advisors/Committee Members: n (gender), Univ.-Prof. Dr. D. Ebner (firstReferee), Dir. u. Prof. Dr. V. Kaden (furtherReferee), PD Dr. E. Uecker (furtherReferee).

Subjects/Keywords: Classical swine fever virus; wild boar; viral replication; virulence; 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche

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APA (6^th Edition):

Tischer, A. (2007). Characterization of virulence of CSFV isolates originating from wild boar. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-9116

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Tischer, Annika. “Characterization of virulence of CSFV isolates originating from wild boar.” 2007. Thesis, Freie Universität Berlin. Accessed March 04, 2021. http://dx.doi.org/10.17169/refubium-9116.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Tischer, Annika. “Characterization of virulence of CSFV isolates originating from wild boar.” 2007. Web. 04 Mar 2021.

Vancouver:

Tischer A. Characterization of virulence of CSFV isolates originating from wild boar. [Internet] [Thesis]. Freie Universität Berlin; 2007. [cited 2021 Mar 04]. Available from: http://dx.doi.org/10.17169/refubium-9116.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Tischer A. Characterization of virulence of CSFV isolates originating from wild boar. [Thesis]. Freie Universität Berlin; 2007. Available from: http://dx.doi.org/10.17169/refubium-9116

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

29. Klinkenberg, Dieudonné. Mathematical epidemiology and the control of classical swine fever virus.

Degree: 2003, University Utrecht

URL: https://dspace.library.uu.nl/handle/1874/301 ; URN:NBN:NL:UI:10-1874-301 ; 1874/301 ; URN:NBN:NL:UI:10-1874-301 ; https://dspace.library.uu.nl/handle/1874/301

► The thesis describes epidemiological research carried out to improve the control of classical swine fever virus (CSFV) epidemics. First, control measures and strategies are investigated… (more)

▼ The thesis describes epidemiological research carried out to improve the control of classical swine fever virus (CSFV) epidemics. First, control measures and strategies are investigated in order to enable quick and adequate action upon CSFV detection. CSFV transmission experiments are described, as well as a mathematical model of CSFV transmission between herds, both used to assess the effectiveness of the E2 subunit marker vaccines with respect to CSFV transmission. Quantification of the effectiveness was done with the basic reproduction ratio Ri (Rh), defined as the number of animals (herds) that is infected by one typical infectious animal (herd) in a completely susceptible population. The transmission experiments pointed out that Ri decreases to below the threshold value 1 as of three weeks after vaccination until at least six months after vaccination. Already one week after vaccination of a pig herd, virus entry will lead to only minor outbreaks. It appeared that the presence of maternal antibodies at the time of vaccination may reduce the antibody levels at later age, but these lower levels still keep Ri below 1. Because vertical transmission is not completely blocked by the vaccine, persistently infected piglets might be born on vaccinated herds. These herds cannot be clinically detected and might thus be a risk for further virus spread. Detection will be possible if some animals, e.g. the breeding sows, on those herds remain unvaccinated. Whether that would lead to an effective control strategy was tested in a mathematical model of CSFV transmission. The model was based on the Dutch CSFV epidemic of 1997/1998, with a moderately virulent virus strain in a pig dense area with relatively many multiplier herds. The model results point out that an effective control strategy (Rh < 1) requires a complete prohibition of transport of unvaccinated animals. Moreover, in addition to the control measures that are obliged by EU legislation (like the tracing of infectious contacts and hygiene measures), the virus transmission between herds should be halved, e.g. by vaccinating 50% of all pig herds. If all animals but the breeding sows would be vaccinated, the demands for a successful control strategy are well met. In addition to the investigation of control measures and strategies, a tool was tested, which had been developed to analyse the effectiveness of the control strategy in an ongoing epidemic. The tool was designed to use data of an ongoing epidemic for estimation of Rh and the number of infected, yet undetected herds. The only data needed for the calculations are the numbers of detected herds in each week of the epidemic. Unfortunately, the only result the model could generate was whether Rh was smaller or larger than 1. Further mathematical research is needed to understand the shortcomings. Until then, some extra data might be used, e.g. an estimate of the number of infected herds at the day of the first detection, or an estimate of the average time between infection of a herd and detection.

Subjects/Keywords: classical swine fever virus; infectious disease; subunit vaccine; veterinary epidemiology; mathematical model; transmission experiment; basic reproduction ratio

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Klinkenberg, D. (2003). Mathematical epidemiology and the control of classical swine fever virus. (Doctoral Dissertation). University Utrecht. Retrieved from https://dspace.library.uu.nl/handle/1874/301 ; URN:NBN:NL:UI:10-1874-301 ; 1874/301 ; URN:NBN:NL:UI:10-1874-301 ; https://dspace.library.uu.nl/handle/1874/301

Chicago Manual of Style (16^th Edition):

Klinkenberg, Dieudonné. “Mathematical epidemiology and the control of classical swine fever virus.” 2003. Doctoral Dissertation, University Utrecht. Accessed March 04, 2021. https://dspace.library.uu.nl/handle/1874/301 ; URN:NBN:NL:UI:10-1874-301 ; 1874/301 ; URN:NBN:NL:UI:10-1874-301 ; https://dspace.library.uu.nl/handle/1874/301.

MLA Handbook (7^th Edition):

Klinkenberg, Dieudonné. “Mathematical epidemiology and the control of classical swine fever virus.” 2003. Web. 04 Mar 2021.

Vancouver:

Klinkenberg D. Mathematical epidemiology and the control of classical swine fever virus. [Internet] [Doctoral dissertation]. University Utrecht; 2003. [cited 2021 Mar 04]. Available from: https://dspace.library.uu.nl/handle/1874/301 ; URN:NBN:NL:UI:10-1874-301 ; 1874/301 ; URN:NBN:NL:UI:10-1874-301 ; https://dspace.library.uu.nl/handle/1874/301.

Council of Science Editors:

Klinkenberg D. Mathematical epidemiology and the control of classical swine fever virus. [Doctoral Dissertation]. University Utrecht; 2003. Available from: https://dspace.library.uu.nl/handle/1874/301 ; URN:NBN:NL:UI:10-1874-301 ; 1874/301 ; URN:NBN:NL:UI:10-1874-301 ; https://dspace.library.uu.nl/handle/1874/301

30. Vos, de, C.J. Risk analysis of classical swine fever introduction.

Degree: 2005, Ponsen & Looijen BV

URL: http://library.wur.nl/WebQuery/wurpubs/340844 ; urn:nbn:nl:ui:32-340844 ; urn:nbn:nl:ui:32-340844 ; http://library.wur.nl/WebQuery/wurpubs/340844

► Keywords:Classical swine fever; Cost-effectiveness; European Union; Pathway diagram; Prevention; Risk analysis; Scenario tree model; Sensitivity analysis; The Netherlands; Virus introduction<o:p></o:p>The research described in this… (more)

▼ Keywords:Classical swine fever; Cost-effectiveness; European Union; Pathway diagram; Prevention; Risk analysis; Scenario tree model; Sensitivity analysis; The Netherlands; Virus introduction<o:p></o:p>The research described in this thesis aimed to support decision-making on preventing classical swine fever virus (CSFV) introduction into disease-free regions of the European Union (EU). A risk analysis of CSFV introduction was performed. The main objective was to provide quantitative insight into the major risk factors contributing to the probability of CSFV introduction (P _CSFV ). First, a pathway diagram was constructed presenting an overview of all factors that might possibly contribute to the P _CSFV . Then, based on this pathway diagram, a scenario tree model was developed to calculate the annual P _CSFV into member states of the EU. The main aim of this model was to analyse quantitatively those pathways that contribute most to the annual P _CSFV, and the origin of these pathways. Pathways included in the model were import of pigs and pork products, returning livestock trucks, and contacts with wild boar. All (old) 15 EU member states were included as possible sources of CSFV introduction. Because the model contained many uncertain input parameters, an extensive sensitivity analysis was performed to indicate which of these parameters most influenced model results. The results indicated that only four out of 257 uncertain input parameters changed the ranking of risk factors, viz. the expected number of classical swine fever epidemics in Germany, Belgium, and the United Kingdom, and the probability that CSFV survives in an empty livestock truck travelling over a distance of 0-900 km. Model calculations based on the situation as at 2003 showed that returning livestock trucks contributed most to the annual P _CSFV into the Netherlands with 50%. The most likely sources of CSFV introduction were Germany, Belgium and Spain. Finally, a cost-effectiveness analysis was performed for six measures aimed at preventing CSFV introduction into the Netherlands. Results showed that using separate livestock trucks for national and international transport was most cost-effective, especially when a worst-case scenario was assumed (i.e. for 0.95 percentile values of the annual P CSFV Advisors/Committee Members: Wageningen University, Ruud Huirne, Helmut Saatkamp.

Subjects/Keywords: classical swine fever virus; varkenspest; risicoschatting; cost effective analysis; ziektepreventie; risicofactoren; nederland; europese unie; Agrarische bedrijfsvoering; Infectieziekten; classical swine fever virus; swine fever; risk assessment; cost effectiveness analysis; disease prevention; risk factors; netherlands; european union; Farm Management; Infectious Diseases

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APA (6^th Edition):

Vos, de, C. J. (2005). Risk analysis of classical swine fever introduction. (Doctoral Dissertation). Ponsen & Looijen BV. Retrieved from http://library.wur.nl/WebQuery/wurpubs/340844 ; urn:nbn:nl:ui:32-340844 ; urn:nbn:nl:ui:32-340844 ; http://library.wur.nl/WebQuery/wurpubs/340844

Chicago Manual of Style (16^th Edition):

Vos, de, C J. “Risk analysis of classical swine fever introduction.” 2005. Doctoral Dissertation, Ponsen & Looijen BV. Accessed March 04, 2021. http://library.wur.nl/WebQuery/wurpubs/340844 ; urn:nbn:nl:ui:32-340844 ; urn:nbn:nl:ui:32-340844 ; http://library.wur.nl/WebQuery/wurpubs/340844.

MLA Handbook (7^th Edition):

Vos, de, C J. “Risk analysis of classical swine fever introduction.” 2005. Web. 04 Mar 2021.

Vancouver:

Vos, de CJ. Risk analysis of classical swine fever introduction. [Internet] [Doctoral dissertation]. Ponsen & Looijen BV; 2005. [cited 2021 Mar 04]. Available from: http://library.wur.nl/WebQuery/wurpubs/340844 ; urn:nbn:nl:ui:32-340844 ; urn:nbn:nl:ui:32-340844 ; http://library.wur.nl/WebQuery/wurpubs/340844.

Council of Science Editors:

Vos, de CJ. Risk analysis of classical swine fever introduction. [Doctoral Dissertation]. Ponsen & Looijen BV; 2005. Available from: http://library.wur.nl/WebQuery/wurpubs/340844 ; urn:nbn:nl:ui:32-340844 ; urn:nbn:nl:ui:32-340844 ; http://library.wur.nl/WebQuery/wurpubs/340844

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